Primary Site >> Pancreatic Cancer

Gene >> TNF

Journal: Gan To Kagaku Ryoho. 1985 Nov;12(11):2185-9.
Title: [Antitumor effect of the tumor necrosis factor against various types of human cancer cells].
Author: Watanabe, N|Niitsu, Y|Neda, H|Sone, H|Yamauchi, N|Umetsu, T|Urushizaki, I
PMID: 4062318
Journal: Pancreas. 1988;3(2):180-8.
Title: Antiproliferative effects exerted by recombinant human tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on human pancreatic tumor cell lines.
Author: Schmiegel, W H|Caesar, J|Kalthoff, H|Greten, H|Schreiber, H W|Thiele, H G
PMID: 3131759
Journal: Nihon Sanka Fujinka Gakkai Zasshi. 1989 Jun;41(6):653-9.
Title: [Low sensitivity of choriocarcinoma cell lines to tumor necrosis factor (TNF)-alpha].
Author: Kameda, T|Negoro, T|Samejima, Y|Takahashi, S|Koyama, M|Matsuzaki, N|Saji, F|Tanizawa, O
PMID: 2504846
Journal: Gan To Kagaku Ryoho. 1989 Aug;16(8 Pt 2):2769-73.
Title: [Clinical efficacy of intratumoral administration of BRM in advanced cancer and their mechanism of actions].
Author: Kuninobu, H|Toge, T|Takayama, T|Baba, N|Kegoya, Y|Yanagawa, E
PMID: 2782888
Journal: Pancreas. 1990 May;5(3):267-77.
Title: Binding and biological effects of tumor necrosis factor and gamma interferon in human pancreatic carcinoma cells.
Author: Raitano, A B|Scuderi, P|Korc, M
PMID: 2111548
Journal: J Interferon Res. 1991 Feb;11(1):61-7.
Title: Upregulation of interferon-gamma binding by tumor necrosis factor and lymphotoxin: disparate potencies of the cytokines and modulation of their effects by phorbol ester.
Author: Raitano, A B|Scuderi, P|Korc, M
PMID: 1903142
Journal: Oncogene. 1991 Jun;6(6):1015-21.
Title: Modulation of platelet-derived growth factor A- and B-chain/c-sis mRNA by tumor necrosis factor and other agents in adenocarcinoma cells.
Author: Kalthoff, H|Roeder, C|Humburg, I|Thiele, H G|Greten, H|Schmiegel, W
PMID: 1906154
Journal: Nihon Geka Gakkai Zasshi. 1992 Jul;93(7):771.
Title: [Effect of lipid A on the production of tumor necrosis factor (TNF) and antitumor activity against pancreatic cancer cells: preliminary report].
Author: Yokomatsu, H|Satake, K
PMID: 1508144
Journal: Invest New Drugs. 1992 Apr;10(1):17-22.
Title: Activity of a recombinant transforming growth factor-alpha-Pseudomonas exotoxin hybrid protein against primary human tumor colony-forming units.
Author: Von Hoff, D D|Marshall, M H|Heimbrook, D C|Stirdivant, S M|Ahern, J D|Herbert, W K|Maigetter, R Z|Oliff, A
PMID: 1607249
Journal: Int J Cancer. 1993 Jul 30;54(6):972-7.
Title: Importance of E-selectin (ELAM-1) and sialyl Lewis(a) in the adhesion of pancreatic carcinoma cells to activated endothelium.
Author: Iwai, K|Ishikura, H|Kaji, M|Sugiura, H|Ishizu, A|Takahashi, C|Kato, H|Tanabe, T|Yoshiki, T
PMID: 7687590
Journal: Int J Cancer. 1993 Jan 21;53(2):328-33.
Title: De novo expression of intercellular adhesion molecule 1 (ICAM-1, CD54) in pancreas cancer.
Author: Schwaeble, W|Kerlin, M|Meyer zum Buschenfelde, K H|Dippold, W
PMID: 8093883
Journal: Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):8972-6.
Title: Inverse regulation of human ERBB2 and epidermal growth factor receptors by tumor necrosis factor alpha.
Author: Kalthoff, H|Roeder, C|Gieseking, J|Humburg, I|Schmiegel, W
PMID: 8105469
Journal: Anticancer Res. 1993 Sep-Oct;13(5A):1501-5.
Title: Anti-proliferative effect of combined tumour necrosis factor-alpha and interferon-alpha on human pancreatic cancer in vitro and in vivo.
Author: Watanabe, T|Fuchimoto, S|Iwagaki, H|Nonaka, Y|Nezu, M|Nishina, T|Marutaka, M|Susaki, K|Naomoto, Y|Shiki, S
PMID: 8239528
Journal: Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):863-7.
Title: Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells.
Author: Schmiegel, W|Roeder, C|Schmielau, J|Rodeck, U|Kalthoff, H
PMID: 8430098
Journal: Biotherapy. 1993;6(1):33-9.
Title: The expression and biological activity of IL-2 receptor on a human pancreas cancer cell line.
Author: Kawami, H|Yoshida, K|Yamaguchi, Y|Saeki, T|Toge, T
PMID: 8507543
Journal: Int J Cancer. 1994 Jan 15;56(2):269-74.
Title: The MHC class-II and CD44 molecules are involved in the induction of tumour necrosis factor (TNF) gene expression by human monocytes stimulated with tumour cells.
Author: Zembala, M|Siedlar, M|Ruggiero, I|Wieckiewicz, J|Mytar, B|Mattei, M|Colizzi, V
PMID: 7508890
Journal: Ann Surg. 1994 Apr;219(4):325-31.
Title: Cytokines, the acute-phase response, and resting energy expenditure in cachectic patients with pancreatic cancer.
Author: Falconer, J S|Fearon, K C|Plester, C E|Ross, J A|Carter, D C
PMID: 7512810
Journal: Hokkaido Igaku Zasshi. 1994 Jul;69(4):767-79.
Title: [Molecular mechanism in hematogenous metastasis of pancreas carcinoma--possible implication of tumor-derived cytokine in a cell-to-cell interaction of pancreas carcinoma and vascular endothelial cells].
Author: Kaji, M
PMID: 7525435
Journal: Pathol Int. 1994 Sep;44(9):688-96.
Title: Lymphokine-activated killer cytotoxicity against pancreas adenocarcinoma cell lines and vascular endothelial cells.
Author: Sugiura, H|Ishikura, H|Omi, M|Kaji, M|Iwai, K|Kishimoto, T|Takahashi, T|Kimura, C|Kato, H|Yoshiki, T
PMID: 7804431
Journal: Anticancer Res. 1994 Nov-Dec;14(6B):2739-42.
Title: Response of adenosquamous carcinoma of the pancreas to interferon-alpha, tumor necrosis factor-alpha and 5-fluorouracil combined treatment.
Author: Tanaka, N|Ohoida, J|Matuno, T|Gouchim, A|Iwagaki, H|Moreira, L F|Orita, K
PMID: 7872711
Journal: Oncology. 1994 Jul-Aug;51(4):360-5.
Title: Recombinant human tumor necrosis factor causes regression in patients with advanced malignancies.
Author: Watanabe, N|Yamauchi, N|Maeda, M|Neda, H|Tsuji, Y|Okamoto, T|Tsuji, N|Akiyama, S|Sasaki, H|Niitsu, Y
PMID: 8208522
Journal: Int J Cancer. 1995 Mar 3;60(5):712-7.
Title: E-selectin expression induced by pancreas-carcinoma-derived interleukin-1 alpha results in enhanced adhesion of pancreas-carcinoma cells to endothelial cells.
Author: Kaji, M|Ishikura, H|Kishimoto, T|Omi, M|Ishizu, A|Kimura, C|Takahashi, T|Kato, H|Yoshiki, T
PMID: 7532161
Journal: Jpn J Cancer Res. 1995 Jan;86(1):72-80.
Title: Characterization of a novel human tumor necrosis factor-alpha mutant with increased cytotoxic activity.
Author: Masegi, T|Kato, A|Kitai, K|Fukuoka, M|Ogawa, H|Ichikawa, Y|Nakamura, S|Watanabe, N|Niitsu, Y
PMID: 7737913
Journal: Cancer Immunol Immunother. 1995 Feb;40(2):95-102.
Title: Characterization of tumor-necrosis-factor-gene-transduced tumor-infiltrating lymphocytes from ascitic fluid of cancer patients: analysis of cytolytic activity, growth rate, adhesion molecule expression and cytokine production.
Author: Itoh, Y|Koshita, Y|Takahashi, M|Watanabe, N|Kohgo, Y|Niitsu, Y
PMID: 7882388
Journal: J Mol Med (Berl). 1995 Aug;73(8):409-16.
Title: Tumor-associated lymphocytes (TAL) are competent to produce higher levels of cytokines in neoplastic pleural and peritoneal effusions than those found in sera and are able to release into culture higher levels of IL-2 and IL-6 than those released by PBMC.
Author: Mantovani, G|Maccio, A|Versace, R|Pisano, M|Lai, P|Esu, S|Ghiani, M|Dessi, D|Turnu, E|Santona, M C
PMID: 8528743
Journal: Pancreas. 1996 Apr;12(3):260-6.
Title: Effects of a new synthetic lipid A on endogenous tumor necrosis factor production and antitumor activity against human pancreatic cancer cells.
Author: Satake, K|Yokomatsu, H|Hiura, A
PMID: 8830332
Journal: Hum Gene Ther. 1996 Oct 1;7(15):1895-905.
Title: Augmented antitumor effects of killer cells induced by tumor necrosis factor gene-transduced autologous tumor cells from gastrointestinal cancer patients.
Author: Sato, Y|Koshita, Y|Hirayama, M|Matuyama, T|Wakimoto, H|Hamada, H|Nitsu, Y
PMID: 8894681
Journal: Pancreas. 1996 Nov;13(4):395-400.
Title: Endogenous tumor necrosis factor inhibits the cytotoxicity of exogenous tumor necrosis factor and adriamycin in pancreatic carcinoma cells.
Author: Watanabe, N|Tsuji, N|Tsuji, Y|Sasaki, H|Okamoto, T|Akiyama, S|Kobayashi, D|Sato, T|Yamauchi, N|Niitsu, Y
PMID: 8899800
Journal: Ann Surg Oncol. 1996 Nov;3(6):564-9.
Title: Differentiation of pancreatic ductal carcinoma cells associated with selective expression of protein kinase C isoforms.
Author: Franz, M G|Norman, J G|Fabri, P J|Gower, W R Jr
PMID: 8915489
Journal: Thyroid. 1996 Dec;6(6):601-6.
Title: Elevated serum interleukin-6 and decreased thyroid hormone levels in postoperative patients and effects of IL-6 on thyroid cell function in vitro.
Author: Murai, H|Murakami, S|Ishida, K|Sugawara, M
PMID: 9001195
Journal: Kobe J Med Sci. 1996 Aug;42(4):219-31.
Title: Synthetic lipid A produces antitumor effect in a hamster pancreatic carcinoma model through production of tumor necrosis factor from activated macrophages.
Author: Morita, S|Yamamoto, M|Kamigaki, T|Saitoh, Y
PMID: 9023454
Journal: J Clin Oncol. 1997 May;15(5):1994-2007.
Title: Superantigen-based immunotherapy: a phase I trial of PNU-214565, a monoclonal antibody-staphylococcal enterotoxin A recombinant fusion protein, in advanced pancreatic and colorectal cancer.
Author: Giantonio, B J|Alpaugh, R K|Schultz, J|McAleer, C|Newton, D W|Shannon, B|Guedez, Y|Kotb, M|Vitek, L|Persson, R|Gunnarsson, P O|Kalland, T|Dohlsten, M|Persson, B|Weiner, L M
PMID: 9164211
Journal: Dig Dis Sci. 1997 Jun;42(6):1290-4.
Title: Biliary interleukin-6 and tumor necrosis factor-alpha in patients undergoing endoscopic retrograde cholangiopancreatography.
Author: Rosen, H R|Winkle, P J|Kendall, B J|Diehl, D L
PMID: 9201097
Journal: Nihon Geka Gakkai Zasshi. 1997 Jul;98(7):639-45.
Title: [Newly-developing therapies of pancreatic cancer--immunotherapy, gene therapy, differentiation therapy, endocrine therapy and others].
Author: Nio, Y|Tamura, K
PMID: 9276872
Journal: Chemotherapy. 1997 Nov-Dec;43(6):406-14.
Title: Endogenous tumor necrosis factor functions as a resistant factor against hyperthermic cytotoxicity in pancreatic carcinoma cells via enhancement of the heart shock element-binding activity of heart shock factor 1.
Author: Watanabe, N|Tsuji, N|Kobayashi, D|Yamauchi, N|Akiyama, S|Sasaki, H|Sato, T|Okamoto, T|Niitsu, Y
PMID: 9395854
Journal: Oncol Res. 1997;9(11-12):623-7.
Title: TNF-alpha induction of A1 expression in human cancer cells.
Author: Pang, X P|Hershman, J M|Karsan, A
PMID: 9563010
Journal: Zhonghua Bing Li Xue Za Zhi. 1997 Oct;26(5):281-4.
Title: [The inhibitory effect of combined treatment of TNF alpha and antisense oligodeoxynucleotides on the growth of human pancreatic carcinoma cell line cells].
Author: Zhang, L|Guo, H|Liu, T
PMID: 10374336
Journal: Oncol Rep. 1997 Sep-Oct;4(5):921-6.
Title: Experimental study of the effect of IL-6 on cancer cachexia.
Author: Ikeda, T|Nishiguchi, Y|Chung, Y|Yamada, N|Sowa, M
PMID: 21590167
Journal: Cancer Res. 1998 Feb 15;58(4):732-6.
Title: Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes.
Author: Brossart, P|Stuhler, G|Flad, T|Stevanovic, S|Rammensee, H G|Kanz, L|Brugger, W
PMID: 9485028
Journal: Ann Surg. 1998 Feb;227(2):249-54.
Title: Albumin synthesis rates are not decreased in hypoalbuminemic cachectic cancer patients with an ongoing acute-phase protein response.
Author: Fearon, K C|Falconer, J S|Slater, C|McMillan, D C|Ross, J A|Preston, T
PMID: 9488524
Journal: Cancer Res. 1998 Apr 15;58(8):1677-83.
Title: An apoptosis-inducing gene therapy for pancreatic cancer with a combination of 55-kDa tumor necrosis factor (TNF) receptor gene transfection and mutein TNF administration.
Author: Sato, T|Yamauchi, N|Sasaki, H|Takahashi, M|Okamoto, T|Sakamaki, S|Watanabe, N|Niitsu, Y
PMID: 9563482
Journal: FEBS Lett. 1998 Oct 2;436(2):139-43.
Title: The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFkappaB.
Author: Schafer, H|Diebel, J|Arlt, A|Trauzold, A|Schmidt, W E
PMID: 9781666
Journal: Arch Biochem Biophys. 1999 Feb 15;362(2):217-24.
Title: Inhibitory effects of streptozotocin, tumor necrosis factor-alpha, and interleukin-1beta on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase.
Author: Park, C|Kim, J R|Shim, J K|Kang, B S|Park, Y G|Nam, K S|Lee, Y C|Kim, C H
PMID: 9989930
Journal: J Surg Res. 1999 May 1;83(1):56-61.
Title: Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells.
Author: McDade, T P|Perugini, R A|Vittimberga, F J Jr|Carrigan, R C|Callery, M P
PMID: 10210643
Journal: Int J Pancreatol. 1999 Feb;25(1):31-7.
Title: Neopterin serum levels in pancreatic adenocarcinoma.
Author: Manes, G|Spada, O A|Rabitti, P G|Feola, B|Misso, S|Minerva, A|Uomo, G
PMID: 10211419
Journal: Pancreas. 1999 May;18(4):378-84.
Title: Human PACAP response gene 1 (p22/PRG1): proliferation-associated expression in pancreatic carcinoma cells.
Author: Schafer, H|Lettau, P|Trauzold, A|Banasch, M|Schmidt, W E
PMID: 10231843
Journal: Ann N Y Acad Sci. 1999 Jun 30;880:83-93.
Title: Hollow-spheres: a new model for analyses of differentiation of pancreatic duct epithelial cells.
Author: Lehnert, L|Trost, H|Schmiegel, W|Roder, C|Kalthoff, H
PMID: 10415853
Journal: Ann N Y Acad Sci. 1999 Jun 30;880:110-21.
Title: Growth factors and cytokines in pancreatic carcinogenesis.
Author: Friess, H|Guo, X Z|Nan, B C|Kleeff, J|Buchler, M W
PMID: 10415856
Journal: Surgery. 1999 Aug;126(2):371-7.
Title: Ubiquitin-proteasome inhibition enhances apoptosis of human pancreatic cancer cells.
Author: McDade, T P|Perugini, R A|Vittimberga, F J Jr|Callery, M P
PMID: 10455908
Journal: Clin Exp Immunol. 1999 Sep;117(3):425-9.
Title: Two polymorphisms of the tumour necrosis factor gene do not influence survival in pancreatic cancer.
Author: Barber, M D|Powell, J J|Lynch, S F|Gough, N J|Fearon, K C|Ross, J A
PMID: 10469042
Journal: Langenbecks Arch Surg. 1999 Oct;384(5):473-8.
Title: Tumor size and lymph-node status in pancreatic carcinoma - is there a correlation to the preoperative immune function?
Author: Wenger, F A|Jacobi, C A|Zieren, J|Docke, W|Volk, H D|Muller, J M
PMID: 10552294
Journal: Scand J Gastroenterol. 2000 Jan;35(1):90-5.
Title: C-met protooncogene expression and its regulation by cytokines in the regenerating pancreas and in pancreatic cancer cells.
Author: Otte, J M|Kiehne, K|Schmitz, F|Folsch, U R|Herzig, K H
PMID: 10672841
Journal: Pancreas. 2000 Mar;20(2):138-45.
Title: Transforming growth factor-beta1 acts as a potent inhibitor of complement C3 biosynthesis in human pancreatic cancer cell lines.
Author: Andoh, A|Shimada, M|Takaya, H|Hata, K|Fujiyama, Y|Bamba, T
PMID: 10707928
Journal: Int J Cancer. 2000 May 1;86(3):399-407.
Title: Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells.
Author: Kleeff, J|Kornmann, M|Sawhney, H|Korc, M
PMID: 10760829
Journal: Biochem Biophys Res Commun. 2000 May 10;271(2):409-13.
Title: Enhanced expression of Silencer of death domains (SODD/BAG-4) in pancreatic cancer.
Author: Ozawa, F|Friess, H|Zimmermann, A|Kleeff, J|Buchler, M W
PMID: 10799310
Journal: Pancreas. 2000 Jul;21(1):32-40.
Title: The expression of chemokine genes correlates with nuclear factor-kappaB activation in human pancreatic cancer cell lines.
Author: Takaya, H|Andoh, A|Shimada, M|Hata, K|Fujiyama, Y|Bamba, T
PMID: 10881930
Journal: J Biol Regul Homeost Agents. 2000 Jul-Sep;14(3):204-8.
Title: Dynamics of diurnal changes in serum concentration of TNF-alpha soluble receptors in gastrointestinal cancer patients.
Author: Muc-Wierzgon, M|Baranowski, M M|Madej, K|Wierzgon, J|Kokot, T|Brodziak, A
PMID: 11037054
Journal: Oncol Rep. 2001 Jan-Feb;8(1):207-12.
Title: Dynamics of circadian fluctuations in serum concentration of cortisol and TNF-alpha soluble receptors in gastrointestinal cancer patients.
Author: Zubelewicz-Szkodzinska, B|Muc-Wierzgon, M|Wierzgon, J|Brodziak, A
PMID: 11115600
Journal: Tissue Antigens. 2001 Jan;57(1):39-45.
Title: Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines.
Author: Seliger, B|Schreiber, K|Delp, K|Meissner, M|Hammers, S|Reichert, T|Pawlischko, K|Tampe, R|Huber, C
PMID: 11169257
Journal: Front Biosci. 2001 Feb 1;6:D164-74.
Title: Loss of skeletal muscle in cancer: biochemical mechanisms.
Author: Tisdale, M J
PMID: 11171557
Journal: Anticancer Res. 2001 Mar-Apr;21(2B):1355-8.
Title: Serum levels of tumor necrosis factor-alpha and nutritional status in pancreatic cancer patients.
Author: Karayiannakis, A J|Syrigos, K N|Polychronidis, A|Pitiakoudis, M|Bounovas, A|Simopoulos, K
PMID: 11396212
Journal: FEBS Lett. 2001 Aug 17;503(2-3):151-7.
Title: The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines.
Author: Liao, Q|Ozawa, F|Friess, H|Zimmermann, A|Takayama, S|Reed, J C|Kleeff, J|Buchler, M W
PMID: 11513873
Journal: Jpn J Cancer Res. 2001 Sep;92(9):983-8.
Title: Augmented adriamycin sensitivity in cells transduced with an antisense tumor necrosis factor gene is mediated by caspase-3 downstream from reactive oxygen species.
Author: Sasaki, M|Kobayashi, D|Watanabe, N
PMID: 11572767
Journal: Dig Dis Sci. 2001 Dec;46(12):2768-72.
Title: Antioxidants inhibit cytokine production and suppress NF-kappaB activation in CAPAN-1 and CAPAN-2 cell lines.
Author: Blanchard, J A 2nd|Barve, S|Joshi-Barve, S|Talwalker, R|Gates, L K Jr
PMID: 11768272
Journal: J Gastrointest Surg. 2001 Nov-Dec;5(6):603-12; discussion 612-3.
Title: PI-3' kinase and NF-kappaB cross-signaling in human pancreatic cancer cells.
Author: Shah, S A|Potter, M W|Hedeshian, M H|Kim, R D|Chari, R S|Callery, M P
PMID: 12086898
Journal: Pancreas. 2002 Mar;24(2):161-8.
Title: The role of oxygen-derived free radicals and nitric oxide in cytokine-induced antiproliferation of pancreatic cancer cells.
Author: Thomas, William J|Thomas, Deborah L|Knezetic, Joseph A|Adrian, Thomas E
PMID: 11854621
Journal: Surg Endosc. 2002 Nov;16(11):1620-6.
Title: Laparoscopic gatrojejunostomy for palliation of gastric outlet obstruction in unresectable gastric cancer.
Author: Choi, Y-B
PMID: 12073005
Journal: Cancer Immunol Immunother. 2002 Oct;51(8):440-8.
Title: Large-scale expansion of CD3(+)CD56(+) lymphocytes capable of lysing autologous tumor cells with cytokine-rich supernatants.
Author: Gritzapis, A D|Dimitroulopoulos, D|Paraskevas, E|Baxevanis, C N|Papamichail, M
PMID: 12202905
Journal: Int J Oncol. 2002 Oct;21(4):881-6.
Title: Cytokine regulation of constitutive production of interleukin-8 and -6 by human pancreatic cancer cell lines and serum cytokine concentrations in patients with pancreatic cancer.
Author: Wigmore, S J|Fearon, K C H|Sangster, K|Maingay, J P|Garden, O J|Ross, J A
PMID: 12239630
Journal: Pancreatology. 2002;2(5):491-4.
Title: Resection of pancreatic cancer normalizes the preoperative increase of tumor necrosis factor alpha gene expression.
Author: Ariapart, Parisa|Bergstedt-Lindqvist, Susanne|van Harmelen, Vanessa|Permert, Johan|Wang, Feng|Lundkvist, Inger
PMID: 12378118
Journal: Anticancer Res. 2002 Nov-Dec;22(6C):4059-63.
Title: Endogenous tumor necrosis factor promotes resistance to cellular stresses by inducing the metallothionein-1A gene.
Author: Hadama, Tohru|Kinoshita, Moritoshi|Kobayashi, Daisuke|Tsuji, Naoki|Watanabe, Naoki
PMID: 12553033
Journal: Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):155-60.
Title: Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis.
Author: Guillermet, Julie|Saint-Laurent, Nathalie|Rochaix, Philippe|Cuvillier, Olivier|Levade, Thierry|Schally, Andrew V|Pradayrol, Lucien|Buscail, Louis|Susini, Christiane|Bousquet, Corinne
PMID: 12490654
Journal: Med Sci Monit. 2003 Jan;9(1):BR43-6.
Title: Experimental studies of serum cytokine concentration following pancreatic electrolytic ablation.
Author: Morrison, Charles P|Teague, Benjamin D|Court, Fiona G|Wemyss-Holden, Simon A|Metcalfe, Mathew S|Dennison, Ashley R|Maddern, Guy J
PMID: 12552236
Journal: Cytokine. 2003 Jan 21;21(2):98-104.
Title: Site-dependent angiogenic cytokine production in human tumor xenografts.
Author: Keyes, Kristan A|Mann, Larry|Teicher, Beverly|Alvarez, Enrique
PMID: 12670449
Journal: Int J Cancer. 2003 Jul 1;105(4):454-8.
Title: Leucine-zipper protein, LDOC1, inhibits NF-kappaB activation and sensitizes pancreatic cancer cells to apoptosis.
Author: Nagasaki, Koichi|Schem, Christian|von Kaisenberg, Constantin|Biallek, Marco|Rosel, Frank|Jonat, Walter|Maass, Nicolai
PMID: 12712434
Journal: J Exp Clin Cancer Res. 2003 Jun;22(2):171-8.
Title: Circadian fluctuations of melatonin, tumor necrosis factor-alpha and its soluble receptors in the circulation of patients with advanced gastrointestinal cancer.
Author: Muc-Wierzgon, M|Nowakowska-Zajdel, E|Zubelewicz, B|Wierzgon, J|Kokot, T|Klakla, K|Szkilnik, R|Wiczkowski, A
PMID: 12866566
Journal: Anticancer Res. 2003 May-Jun;23(3B):2267-73.
Title: Diverse responses between human pancreatic cancer cell lines to native alpha 1-antitrypsin and its C-terminal fragment.
Author: Zelvyte, Inga|Ohlsson, Bodil|Axelson, Jan|Janciauskiene, Sabina
PMID: 12894502
Journal: Eur J Gastroenterol Hepatol. 2003 Nov;15(11):1223-7.
Title: Analysis of tumour necrosis factor alpha and interleukin 10 promotor variants in patients with chronic pancreatitis.
Author: Beranek, Helen|Teich, Niels|Witt, Heiko|Schulz, Hans-Ulrich|Mossner, Joachim|Keim, Volker
PMID: 14560157
Journal: J Surg Res. 2004 Jan;116(1):121-3.
Title: The lack of a systemic inflammatory response syndrome supports the safety of pancreatic electrolysis: experimental studies.
Author: Teague, Benjamin D|Morrison, Charles P|Court, Fiona G|Nguyen, Trung|Wemyss-Holden, Simon A|Dennison, Ashley R|Maddern, Guy J
PMID: 14732357
Journal: Int J Radiat Oncol Biol Phys. 2004 Feb 1;58(2):580-8.
Title: A bispecific antibody to enhance radiotherapy by tumor necrosis factor-alpha in human CEA-expressing digestive tumors.
Author: Azria, David|Larbouret, Christel|Garambois, Veronique|Gourgou, Sophie|Martineau, Pierre|Robert, Bruno|Dubois, Jean-Bernard|Pelegrin, Andre
PMID: 14751531
Journal: Cancer Immun. 2004 Aug 25;4:8.
Title: Prevention and reversal of tumor cell-induced monocyte deactivation by cytokines, purified protein derivative (PPD), and anti-IL-10 antibody.
Author: Baj-Krzyworzeka, Monika|Baran, Jaroslaw|Szatanek, Rafal|Stankiewicz, Danuta|Siedlar, Maciej|Zembala, Marek
PMID: 15327279
Journal: Gan To Kagaku Ryoho. 2004 Sep;31(9):1407-10.
Title: [A case report of metastatic pancreatic cancer that responded remarkably to the combination of thalidomide, celecoxib and irinotecan].
Author: Hada, Masato|Mizutari, Kazuhiro
PMID: 15446566
Journal: Life Sci. 2004 Oct 29;75(24):2853-66.
Title: Protective effects of SP600125 a new inhibitor of c-jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK1/2) in an experimental model of cerulein-induced pancreatitis.
Author: Minutoli, Letteria|Altavilla, Domenica|Marini, Herbert|Passaniti, Maria|Bitto, Alessandra|Seminara, Paolo|Venuti, Francesco S|Famulari, Ciro|Macri, Antonio|Versaci, Antonino|Squadrito, Francesco
PMID: 15454338
Journal: Gan To Kagaku Ryoho. 2004 Oct;31(11):1649-51.
Title: [The repetitive immune cell transfer therapy combining non-myelosuppressive chemotherapy for patients with advanced and refractory cancer].
Author: Toh, Uhi|Fujii, Teruhiko|Tayama, Kousuke|Yanaga, Hiroshi|Yokoyama, Goro|Yamaguchi, Miki|Horiuchi, Hiroyuki|Sasatomi, Teruo|Takamori, Shinzo|Shirouzu, Kazuo|Seki, Naoko|Yamana, Hideaki
PMID: 15553672
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2004 Nov;35(6):839-42.
Title: [Study on acute pancreatitis-associated lung injury induced by L-arginine in mice].
Author: Zhao, Qiu-ling|Huang, Cheng-yu|Huang, Ying|Wang, Jun-fang|Liu, Jing
PMID: 15573769
Journal: Int J Cancer. 2005 Feb 10;113(4):649-53.
Title: Combined therapy of experimental pancreatic cancer with CYP2B1 producing cells: low-dose ifosfamide and local tumor irradiation.
Author: Ryschich, Eduard|Jesnowski, Ralf|Ringel, Jorg|Harms, Walter|Fabian, Oliver V|Saller, Robert|Schrewe, Michael|Engel, Alexander|Schmidt, Jan|Lohr, Matthias
PMID: 15455374
Journal: Gut. 2005 Apr;54(4):540-5.
Title: Thalidomide in the treatment of cancer cachexia: a randomised placebo controlled trial.
Author: Gordon, J N|Trebble, T M|Ellis, R D|Duncan, H D|Johns, T|Goggin, P M
PMID: 15753541
Journal: Cancer Res. 2005 Mar 15;65(6):2344-52.
Title: Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro.
Author: Bai, Jirong|Sui, Jianhua|Demirjian, Aram|Vollmer, Charles M Jr|Marasco, Wayne|Callery, Mark P
PMID: 15781649
Journal: Int J Oncol. 2005 Nov;27(5):1247-55.
Title: Enhancement of the caspase-independent apoptotic sensitivity of pancreatic cancer cells by DHMEQ, an NF-kappaB inhibitor.
Author: Matsumoto, Gaku|Muta, Mariko|Umezawa, Kazuo|Suzuki, Tomoyoshi|Misumi, Keizo|Tsuruta, Koji|Okamoto, Atsutake|Toi, Masakazu
PMID: 16211219
Journal: J Clin Oncol. 2005 Dec 1;23(34):8679-87.
Title: Phase I study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: expression analysis of genes related to outcome.
Author: Saif, M Wasif|Eloubeidi, Mohammaed A|Russo, Suzanne|Steg, Adam|Thornton, Jennifer|Fiveash, John|Carpenter, Mark|Blanquicett, Carmello|Diasio, Robert B|Johnson, Martin R
PMID: 16314628
Journal: Rev Diabet Stud. 2005 Fall;2(3):146-56.
Title: Insulinotropic and anti-inflammatory effects of rosiglitazone in experimental autoimmune diabetes.
Author: Awara, Wageh M|el-Sisi, Alaa E|el-Refaei, Mohamed|el-Naa, Mona M|el-Desoky, Karima
PMID: 17491689
Journal: Eur J Pharmacol. 2006 Feb 17;532(1-2):187-93.
Title: Beneficial effect of resveratrol on cholecystokinin-induced experimental pancreatitis.
Author: Szabolcs, Annamaria|Varga, Ilona S|Varga, Csaba|Berko, Aniko|Kaszaki, Jozsef|Letoha, Tamas|Tiszlavicz, Laszlo|Sari, Reka|Lonovics, Janos|Takacs, Tamas
PMID: 16499907
Journal: Cancer Chemother Pharmacol. 2006 Dec;58(6):771-5.
Title: Radiation recall phenomenon secondary to capecitabine: possible role of thymidine phosphorylase.
Author: Saif, Muhammad Wasif|Black, Glenda|Johnson, Martin|Russo, Suzanne|Diasio, Robert
PMID: 16552574
Journal: Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):726-31.
Title: Inflammation, genetic polymorphisms in proinflammatory genes TNF-A, RANTES, and CCR5, and risk of pancreatic adenocarcinoma.
Author: Duell, Eric J|Casella, Daniel P|Burk, Robert D|Kelsey, Karl T|Holly, Elizabeth A
PMID: 16614115
Journal: Pancreas. 2006 May;32(4):396-402.
Title: The expression of adhesion molecules and the influence of inflammatory cytokines on the adhesion of human pancreatic carcinoma cells to mesothelial monolayers.
Author: van Grevenstein, Wilhelmina M U|Hofland, Leo J|Jeekel, Johannes|van Eijck, Casper H J
PMID: 16670622
Journal: Pancreas. 2006 Jul;33(1):31-7.
Title: Clinical monitoring of innate cellular immunity of monocytes/macrophages by tumor necrosis factor alpha productivity in whole blood stimulated by lipopolysaccharide in patients with pancreatic cancer.
Author: Terakawa, Naoyoshi|Satoi, Sohei|Takai, Soichiro|Yanagimoto, Hiroaki|Takahashi, Kanji|Komiyama, Yutaka|A-Hon, Kwon|Kamiyama, Yasuo|Takahashi, Hakuo
PMID: 16804410
Journal: Cancer Res. 2006 Sep 15;66(18):9045-53.
Title: Aberrant expression of a disintegrin and metalloproteinase 17/tumor necrosis factor-alpha converting enzyme increases the malignant potential in human pancreatic ductal adenocarcinoma.
Author: Ringel, Jorg|Jesnowski, Ralf|Moniaux, Nicolas|Luttges, Jutta|Ringel, Jens|Choudhury, Amit|Batra, Surinder K|Kloppel, Gunter|Lohr, Matthias
PMID: 16982746
Journal: J Immunother. 2007 Jan;30(1):108-15.
Title: Impact of interferon-alpha in combined chemoradioimmunotherapy for pancreatic adenocarcinoma (CapRI): first data from the immunomonitoring.
Author: Schmidt, Jan|Jager, Dirk|Hoffmann, Kartin|Buchler, Markus W|Marten, Angela
PMID: 17198089
Journal: Langenbecks Arch Surg. 2007 May;392(3):353-8.
Title: Systemic immune dysfunction in pancreatic cancer patients.
Author: Poch, Bertram|Lotspeich, Errki|Ramadani, Marco|Gansauge, Susanne|Beger, Hans G|Gansauge, Frank
PMID: 17235586
Journal: J Surg Res. 2007 May 1;139(1):106-12.
Title: G2/M cell-cycle arrest and apoptosis by n-3 fatty acids in a pancreatic cancer model.
Author: Dekoj, Thomas|Lee, Sang|Desai, Sagun|Trevino, Jose|Babcock, Tricia A|Helton, W Scott|Espat, N Joseph
PMID: 17291531
Journal: J Gastroenterol Hepatol. 2007 Mar;22(3):371-6.
Title: Effects of thalidomide in experimental models of post-endoscopic retrograde cholangiopancreatography pancreatitis.
Author: Xiong, Guang-Su|Wu, Shu-Ming|Wang, Zhen-Hua|Mo, Jian-Zhong|Xiao, Shu-Dong
PMID: 17295769
Journal: Int J Oncol. 2007 Apr;30(4):977-83.
Title: Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression.
Author: Kamohara, Hidenobu|Ogawa, Michio|Ishiko, Takatoshi|Sakamoto, Kiyoshi|Baba, Hideo
PMID: 17332938
Journal: Dig Dis Sci. 2007 Oct;52(10):2646-52. Epub 2007 Mar 15.
Title: Synthetic serine protease inhibitor, gabexate mesilate, prevents nuclear factor-kappaB activation and increases TNF-alpha-mediated apoptosis in human pancreatic cancer cells.
Author: Takahashi, Hiroki|Funahashi, Hitoshi|Sawai, Hirozumi|Matsuo, Yoichi|Yamamoto, Minoru|Okada, Yuji|Takeyama, Hiromitsu|Manabe, Tadao
PMID: 17357832
Journal: Int J Oncol. 2007 Sep;31(3):627-32.
Title: Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-alpha and leukemia inhibitory factor in pancreatic carcinoma cells: Impact of CXCL-8 as an autocrine growth factor.
Author: Kamohara, Hidenobu|Takahashi, Masashi|Ishiko, Takatoshi|Ogawa, Michio|Baba, Hideo
PMID: 17671691
Journal: Cancer J. 2007 Jul-Aug;13(4):247-56.
Title: Phase II study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: up-regulation of thymidine phosphorylase.
Author: Saif, Muhammad Wasif|Black, Glenda|Roy, Shalija|Bell, Diana|Russo, Suzanne|Eloubeidi, Mohamed A|Steg, Adam|Johnson, Martin R|Zelterman, Daniel|Diasio, Robert B
PMID: 17762760
Journal: Biochem Pharmacol. 2008 Feb 15;75(4):836-46.
Title: The immunocytokine scFv23/TNF targeting HER-2/neu induces synergistic cytotoxic effects with 5-fluorouracil in TNF-resistant pancreatic cancer cell lines.
Author: Lyu, Mi-Ae|Kurzrock, Razelle|Rosenblum, Michael G
PMID: 18082672
Journal: Cancer Res. 2008 Mar 1;68(5):1443-50.
Title: Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis.
Author: Egberts, Jan-Hendrik|Cloosters, Vera|Noack, Andreas|Schniewind, Bodo|Thon, Lutz|Klose, Stefanie|Kettler, Bastian|von Forstner, Corinna|Kneitz, Christian|Tepel, Jurgen|Adam, Dieter|Wajant, Harald|Kalthoff, Holger|Trauzold, Anna
PMID: 18316608
Journal: Anticancer Res. 2008 Jan-Feb;28(1B):379-87.
Title: Adoptive immunotherapy for pancreatic cancer using MUC1 peptide-pulsed dendritic cells and activated T lymphocytes.
Author: Kondo, Hiroshi|Hazama, Shoichi|Kawaoka, Toru|Yoshino, Shigefumi|Yoshida, Shin|Tokuno, Kazuhisa|Takashima, Motonari|Ueno, Tomio|Hinoda, Yuji|Oka, Masaaki
PMID: 18383873
Journal: Biomed Res. 2008 Apr;29(2):99-103.
Title: Period is involved in the proliferation of human pancreatic MIA-PaCa2 cancer cells by TNF-alpha.
Author: Suzuki, Takahiro|Sato, Fuyuki|Kondo, Jun|Liu, Yang|Kusumi, Tomomi|Fujimoto, Katsumi|Kato, Yukio|Sato, Tatsusuke|Kijima, Hiroshi
PMID: 18480551
Journal: Int J Mol Med. 2008 Nov;22(5):645-9.
Title: Claudin-1 expression is induced by tumor necrosis factor-alpha in human pancreatic cancer cells.
Author: Kondo, Jun|Sato, Fuyuki|Kusumi, Tomomi|Liu, Yang|Motonari, Ohashi|Sato, Tatsusuke|Kijima, Hiroshi
PMID: 18949385
Journal: Z Gastroenterol. 2008 Dec;46(12):1384-92.
Title: [Molecular mechanisms and its clinical impact in cancer cachexia].
Author: Bachmann, J|Friess, H|Martignoni, M E
PMID: 19053008
Journal: FASEB J. 2009 Jan;23(1):21-33.
Title: Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo.
Author: Kasperczyk, Hubert|Baumann, Bernd|Debatin, Klaus-Michael|Fulda, Simone
PMID: 18772349
Journal: Cancer Gene Ther. 2009 Apr;16(4):373-81.
Title: Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
Author: Mauceri, H J|Beckett, M A|Liang, H|Sutton, H G|Pitroda, S|Galka, E|Efimova, E|Darga, T|Khodarev, N N|King, C R|Posner, M C|Hellman, S|Kufe, D W|Weichselbaum, R R
PMID: 18974777
Journal: Int J Oncol. 2009 May;34(5):1341-52.
Title: AMT: preclinical pharmacology studies.
Author: Niazi, Faiz|Drevs, Joachim|Diergarten, Klaus|Dorn, Annette|Maier, Armin|Fiebig, Heinz Herbert|Bruyns, Eddy|Scheele, Jurgen
PMID: 19360346
Journal: J Biol Chem. 2009 Jun 26;284(26):17868-76.
Title: Interleukin-32 expression in the pancreas.
Author: Nishida, Atsushi|Andoh, Akira|Inatomi, Osamu|Fujiyama, Yoshihide
PMID: 19386602
Journal: Int J Cancer. 2009 Aug 15;125(4):942-51.
Title: Targeting AKT with the proapoptotic peptide, TAT-CTMP: a novel strategy for the treatment of human pancreatic adenocarcinoma.
Author: Simon, Peter O Jr|McDunn, Jonathan E|Kashiwagi, Hiroyuki|Chang, Katherine|Goedegebuure, Peter S|Hotchkiss, Richard S|Hawkins, William G
PMID: 19405118
Journal: BMC Cancer. 2009 Apr 30;9:132.
Title: Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy.
Author: Mamaghani, Shadi|Patel, Satish|Hedley, David W
PMID: 19405981
Journal: Cancer Gene Ther. 2009 Aug;16(8):609-19.
Title: Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.
Author: Weichselbaum, R R|Kufe, D
PMID: 19444302
Journal: Cancer Gene Ther. 2009 Nov;16(11):841-7.
Title: Combination of human tumor necrosis factor-alpha (hTNF-alpha) gene delivery with gemcitabine is effective in models of pancreatic cancer.
Author: Murugesan, S R|King, C R|Osborn, R|Fairweather, W R|O'Reilly, E M|Thornton, M O|Wei, L L
PMID: 19444305
Journal: Biochem Biophys Res Commun. 2009 Sep 11;387(1):139-42.
Title: CMTM5 induces apoptosis of pancreatic cancer cells and has synergistic effects with TNF-alpha.
Author: Guo, Xiaohuan|Li, Ting|Wang, Yu|Shao, Luning|Zhang, Yingmei|Ma, Dalong|Han, Wenling
PMID: 19577543
Journal: JOP. 2009 Sep 4;10(5):535-8.
Title: Surgical resection after TNFerade therapy for locally advanced pancreatic cancer.
Author: Chadha, Manpreet K|Litwin, Alan|Levea, Charles|Iyer, Renuka|Yang, Gary|Javle, Milind|Gibbs, John F
PMID: 19734632
Journal: HPB (Oxford). 2009 Aug;11(5):373-81.
Title: Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells.
Author: Chehl, Navdeep|Chipitsyna, Galina|Gong, Qiaoke|Yeo, Charles J|Arafat, Hwyda A
PMID: 19768141
Journal: Eur J Cell Biol. 2009 Dec;88(12):743-52.
Title: Blood monocytes stimulate migration of human pancreatic carcinoma cells in vitro: the role of tumour necrosis factor - alpha.
Author: Baran, Bartlomiej|Bechyne, Iga|Siedlar, Maciej|Szpak, Katarzyna|Mytar, Bozenna|Sroka, Jolanta|Laczna, Eliza|Madeja, Zbigniew|Zembala, Marek|Czyz, Jaroslaw
PMID: 19782426
Journal: Nutr Cancer. 2009;61(5):687-95.
Title: Effects of conjugated linoleic acid on myogenic and inflammatory responses in a human primary muscle and tumor coculture model.
Author: Larsen, Amy E|Crowe, Timothy C
PMID: 19838943
Journal: J Cell Mol Med. 2009 Sep;13(9B):4023-33.
Title: Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma.
Author: Salnikov, Alexei V|Groth, Ariane|Apel, Anja|Kallifatidis, Georgios|Beckermann, Benjamin M|Khamidjanov, Akmal|Ryschich, Eduard|Buchler, Markus W|Herr, Ingrid|Moldenhauer, Gerhard
PMID: 20196789
Journal: Cytokine. 2010 Jan;49(1):15-23.
Title: Effects of carbon monoxide releasing molecule-liberated CO on severe acute pancreatitis in rats.
Author: Chen, Ping|Sun, Bei|Chen, Hua|Wang, Gang|Pan, Shangha|Kong, Rui|Bai, Xuewei|Wang, Shuangjia
PMID: 19900821
Journal: Lab Invest. 2010 Mar;90(3):426-35.
Title: Potential carcinogenic effects of cigarette smoke and Swedish moist snuff on pancreas: a study using a transgenic mouse model of chronic pancreatitis.
Author: Song, Zhigang|Bhagat, Govind|Quante, Michael|Baik, Gwang Ho|Marrache, Frederic|Tu, Shui Ping|Zhao, Chun-Mei|Chen, Duan|Dannenberg, Andrew J|Wang, Timothy C
PMID: 20065943
Journal: Mol Ther. 2010 May;18(5):912-20.
Title: Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-beta-dependent activation of antigen-specific CD8+ T cells.
Author: Meng, Yuru|Mauceri, Helena J|Khodarev, Nikolai N|Darga, Thomas E|Pitroda, Sean P|Beckett, Michael A|Kufe, Donald W|Weichselbaum, Ralph R
PMID: 20197756
Journal: Cancer Sci. 2010 May;101(5):1226-33.
Title: Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis.
Author: Li, Wei|Xie, Li|Chen, Zheng|Zhu, Yi|Sun, Yujie|Miao, Yi|Xu, Zekuan|Han, Xiao
PMID: 20331621
Journal: Cancer Lett. 2010 Sep 28;295(2):214-28.
Title: NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells.
Author: Maier, Harald J|Schmidt-Strassburger, Uta|Huber, Margit A|Wiedemann, Eva M|Beug, Hartmut|Wirth, Thomas
PMID: 20350779
Journal: Life Sci. 2010 Jul 3;87(1-2):64-8.
Title: Protective effect of cyclosporin A on brain injury in rats with acute necrotic pancreatitis.
Author: Qian, Nian-Song|Xu, Xiao-Ping|Chen, Yong|Dou, Ke-Feng|Wang, Ya-Yun|Yang, Yan-Ling
PMID: 20561905
Journal: IDrugs. 2010 Jul;13(7):424-6.
Title: Digestive Disease Week 2010. Turning Science into Medicine--part 2.
Author: Hodgkinson, Lisa
PMID: 20582861
Journal: Zhong Xi Yi Jie He Xue Bao. 2010 Jul;8(7):655-61.
Title: Effects of Qingyi Huaji decoction on serum levels of interleukin-6, interleukin-8 and tumor necrosis factor-alpha in nude mice bearing pancreatic tumors.
Author: Ouyang, Hua-Qiang|Liu, Lu-Ming|Chen, Zhen|Luo, Jian-Min|Yu, Er-Xin
PMID: 20619142
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Oct;299(4):G821-32.
Title: Nuclear expression of interleukin-33 in pancreatic stellate cells.
Author: Masamune, Atsushi|Watanabe, Takashi|Kikuta, Kazuhiro|Satoh, Kennichi|Kanno, Atsushi|Shimosegawa, Tooru
PMID: 20689058
Journal: PLoS One. 2010 Aug 19;5(8):e12243.
Title: Examination of apoptosis signaling in pancreatic cancer by computational signal transduction analysis.
Author: Ruckert, Felix|Dawelbait, Gihan|Winter, Christof|Hartmann, Arndt|Denz, Axel|Ammerpohl, Ole|Schroeder, Michael|Schackert, Hans Konrad|Sipos, Bence|Kloppel, Gunter|Kalthoff, Holger|Saeger, Hans-Detlev|Pilarsky, Christian|Grutzmann, Robert
PMID: 20808857
Journal: Anticancer Res. 2010 Dec;30(12):5257-61.
Title: Association between EGF, TGF-{beta}1, TNF-{alpha} gene polymorphisms and cancer of the pancreatic head.
Author: Wu, Guo-Yang|Lu, Qingjun|Hasenberg, Till|Niedergethmann, Marco|Post, Stefan|Sturm, Jorg W|Keese, Michael
PMID: 21187523
Journal: Cancer Lett. 2011 May 28;304(2):117-27.
Title: PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKalpha and sustained activation of the NF-kappaB pathway.
Author: Li, Wei|Chen, Zheng|Zong, Yang|Gong, Feiran|Zhu, Yi|Zhu, Yunxia|Lv, Jinghuan|Zhang, Jingjing|Xie, Li|Sun, Yujie|Miao, Yi|Tao, Min|Han, Xiao|Xu, Zekuan
PMID: 21376459
Journal: Arch Physiol Biochem. 2011 May;117(2):78-87.
Title: Altered expression of genes in adipose tissues associated with reduced fat mass in patients with pancreatic cancer.
Author: Haugen, F|Labori, K J|Noreng, H J|Buanes, T|Iversen, P O|Drevon, C A
PMID: 21457003
Journal: Cancer Lett. 2011 Jul 1;306(1):92-8.
Title: Combination treatment using adenovirus vector-mediated tumor necrosis factor-alpha gene transfer and a NF-kappaB inhibitor for pancreatic cancer in mice.
Author: Furukawa, Kenei|Ohashi, Toya|Haruki, Koichiro|Fujiwara, Yuki|Iida, Tomonori|Shiba, Hiroaki|Uwagawa, Tadashi|Kobayashi, Hiroshi|Yanaga, Katsuhiko
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Journal: Cancer Immunol Immunother. 2011 Aug;60(8):1097-107.
Title: Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study.
Author: Bauer, Christian|Dauer, Marc|Saraj, Samira|Schnurr, Maximilian|Bauernfeind, Franz|Sterzik, Alexander|Junkmann, Jana|Jakl, Veronika|Kiefl, Rosemarie|Oduncu, Fuat|Emmerich, Bertold|Mayr, Doris|Mussack, Thomas|Bruns, Christiane|Ruttinger, Dominik|Conrad, Cla
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Journal: Gastroenterol Res Pract. 2011;2011:214269.
Title: Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer.
Author: Bu, Xianmin|Zhao, Chenghai|Dai, Xianwei
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Journal: Mol Cancer. 2011 Aug 31;10:106.
Title: Mesothelin confers pancreatic cancer cell resistance to TNF-alpha-induced apoptosis through Akt/PI3K/NF-kappaB activation and IL-6/Mcl-1 overexpression.
Author: Bharadwaj, Uddalak|Marin-Muller, Christian|Li, Min|Chen, Changyi|Yao, Qizhi
PMID: 21880146
Journal: Folia Histochem Cytobiol. 2011;49(3):512-20.
Title: Induction of monocyte antitumor response by human cancer cells transduced with TNF-GFP fusion gene: possible implications for immunotherapy of cancer.
Author: Wieckiewicz, Jerzy|Mytar, Bozenna|Szatanek, Rafal|Weglarczyk, Kazimierz|Baran, Jaroslaw
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Journal: J Clin Invest. 2011 Dec;121(12):4685-99.
Title: Crosstalk between the canonical NF-kappaB and Notch signaling pathways inhibits Ppargamma expression and promotes pancreatic cancer progression in mice.
Author: Maniati, Eleni|Bossard, Maud|Cook, Natalie|Candido, Juliana B|Emami-Shahri, Nia|Nedospasov, Sergei A|Balkwill, Frances R|Tuveson, David A|Hagemann, Thorsten
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Journal: Antioxid Redox Signal. 2012 Mar 1;16(5):413-27.
Title: Zyflamend sensitizes tumor cells to TRAIL-induced apoptosis through up-regulation of death receptors and down-regulation of survival proteins: role of ROS-dependent CCAAT/enhancer-binding protein-homologous protein pathway.
Author: Kim, Ji Hye|Park, Byoungduck|Gupta, Subash C|Kannappan, Ramaswamy|Sung, Bokyung|Aggarwal, Bharat B
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Journal: J Gastrointest Surg. 2012 Mar;16(3):460-8.
Title: Accumulation of pro-cancer cytokines in the plasma fraction of stored packed red cells.
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Journal: Gastrointest Endosc. 2012 Feb;75(2):332-8.
Title: EUS or percutaneously guided intratumoral TNFerade biologic with 5-fluorouracil and radiotherapy for first-line treatment of locally advanced pancreatic cancer: a phase I/II study.
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Journal: Oncol Rep. 2012 May;27(5):1497-503.
Title: Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells.
Author: Liu, Lihua|Meng, Jun|Zhang, Cong|Duan, Yuqing|Zhao, Lianmei|Wang, Shijie|Shan, Baoen
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Journal: Biotechnol Lett. 2012 Jul;34(7):1235-41.
Title: Changes in the expression of serum markers CA242, CA199, CA125, CEA, TNF-alpha and TSGF after cryosurgery in pancreatic cancer patients.
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Journal: Zhonghua Yi Xue Za Zhi. 2012 Apr 10;92(14):993-8.
Title: [Protective effects and possible mechanism of lipoxin A(4) analogue in rats with acute pancreatitis].
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Journal: JOP. 2012 Jul 10;13(4):354-7.
Title: New tools and novel approaches in treating locally advanced pancreatic adenocarcinoma.
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Journal: J Transl Med. 2012 Sep 11;10:189.
Title: Effect of high-dose intravenous vitamin C on inflammation in cancer patients.
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Journal: Life Sci. 2012 Oct 29;91(17-18):866-71.
Title: Protective effects of alpha-pinene in mice with cerulein-induced acute pancreatitis.
Author: Bae, Gi-Sang|Park, Kyoung-Chel|Choi, Sun Bok|Jo, Il-Joo|Choi, Mee-Ok|Hong, Seung-Heon|Song, Kyung|Song, Ho-Joon|Park, Sung-Joo
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Journal: Cancer Genomics Proteomics. 2012 Sep-Oct;9(5):287-95.
Title: Single nucleotide polymorphisms of genes for EGF, TGF-beta and TNF-alpha in patients with pancreatic carcinoma.
Author: Zhang, Lei|Wu, Guoyang|Herrle, Florian|Niedergethmann, Marco|Keese, Michael
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Journal: Gut Pathog. 2012 Sep 24;4(1):10.
Title: In vitro cytokine profiles and viability of different human cells treated with whole cell lysate of Mycobacterium avium subsp. paratuberculosis.
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Journal: J Biol Chem. 2012 Nov 30;287(49):40924-37.
Title: The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.
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Journal: Anticancer Res. 2012 Nov;32(11):4813-21.
Title: Desensitization of NFkappaB for overcoming chemoresistance of pancreatic cancer cells to TNF-alpha or paclitaxel.
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Journal: Anticancer Agents Med Chem. 2013 Feb;13(2):276-80.
Title: The role of mesothelin in tumor progression and targeted therapy.
Author: Tang, Zhewei|Qian, Min|Ho, Mitchell
PMID: 22721387
Journal: J Infect Chemother. 2013 Feb;19(1):166-70.
Title: Detection of Legionella pneumophila serogroup 1 in blood cultures from a patient treated with tumor necrosis factor-alpha inhibitor.
Author: Kaku, Norihito|Yanagihara, Katsunori|Morinaga, Yoshitomo|Sato, Tsuyoshi|Nakashima, Munetoshi|Sakai, Takahiro|Tominaga, Hiroo|Wakigawa, Fumiko|Nagashima, Seiji|Fukuda, Minoru|Hashiguchi, Kohji|Kohno, Shigeru
PMID: 22911089
Journal: J Am Coll Surg. 2013 Feb;216(2):320-32.e3.
Title: Inhibition of nuclear factor kappa-B enhances the antitumor effect of combination treatment with tumor necrosis factor-alpha gene therapy and gemcitabine for pancreatic cancer in mice.
Author: Fujiwara, Yuki|Shiba, Hiroaki|Iwase, Ryota|Haruki, Koichiro|Furukawa, Kenei|Uwagawa, Tadashi|Misawa, Takeyuki|Ohashi, Toya|Yanaga, Katsuhiko
PMID: 23219147
Journal: J Transl Med. 2013 Feb 9;11:35.
Title: Microenvironment generated during EGFR targeted killing of pancreatic tumor cells by ATC inhibits myeloid-derived suppressor cells through COX2 and PGE2 dependent pathway.
Author: Thakur, Archana|Schalk, Dana|Tomaszewski, Elyse|Kondadasula, Sri Vidya|Yano, Hiroshi|Sarkar, Fazlul H|Lum, Lawrence G
PMID: 23394575
Journal: Pancreas. 2013 Jul;42(5):813-8.
Title: Disrupting cytokine signaling in pancreatic cancer: a phase I/II study of etanercept in combination with gemcitabine in patients with advanced disease.
Author: Wu, Christina|Fernandez, Soledad A|Criswell, Tamara|Chidiac, Tarek A|Guttridge, Denis|Villalona-Calero, Miguel|Bekaii-Saab, Tanios S
PMID: 23429495
Journal: Clin Cancer Res. 2013 Apr 15;19(8):2025-35.
Title: Targeting the NF-kappaB and mTOR pathways with a quinoxaline urea analog that inhibits IKKbeta for pancreas cancer therapy.
Author: Radhakrishnan, Prakash|Bryant, Vashti C|Blowers, Elizabeth C|Rajule, Rajkumar N|Gautam, Nagsen|Anwar, Muhammad M|Mohr, Ashley M|Grandgenett, Paul M|Bunt, Stephanie K|Arnst, Jamie L|Lele, Subodh M|Alnouti, Yazen|Hollingsworth, Michael A|Natarajan, Amarnath
PMID: 23444213
Journal: Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):855-61.
Title: Inflammatory plasma markers and pancreatic cancer risk: a prospective study of five U.S. cohorts.
Author: Bao, Ying|Giovannucci, Edward L|Kraft, Peter|Qian, Zhi Rong|Wu, Chen|Ogino, Shuji|Gaziano, J Michael|Stampfer, Meir J|Ma, Jing|Buring, Julie E|Sesso, Howard D|Lee, I-Min|Rifai, Nader|Pollak, Michael N|Jiao, Li|Lessin, Lawrence|Cochrane, Barbara B|Manson,
PMID: 23462920
Journal: BMC Cancer. 2013 Apr 17;13:194.
Title: Dimethylaminoparthenolide and gemcitabine: a survival study using a genetically engineered mouse model of pancreatic cancer.
Author: Yip-Schneider, Michele T|Wu, Huangbing|Stantz, Keith|Agaram, Narasimhan|Crooks, Peter A|Schmidt, C Max
PMID: 23590467
Journal: Int J Mol Med. 2013 Jul;32(1):85-92.
Title: Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl1 and TCTP and increases that of TNF-alpha and Bax in BxPC3 pancreatic carcinoma cells.
Author: Chien, Su-Yu|Kuo, Shou-Jen|Chen, Dar-Ren|Su, Chin-Cheng
PMID: 23652631
Journal: PPAR Res. 2013;2013:121956.
Title: Role of Peroxisome Proliferator-Activated Receptor beta/delta and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells.
Author: Coleman, Jeffrey D|Thompson, Jerry T|Smith, Russell W 3rd|Prokopczyk, Bogdan|Vanden Heuvel, John P
PMID: 23737761
Journal: J Cell Biol. 2013 Aug 5;202(3):563-77.
Title: Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-kappaB and MMPs.
Author: Liou, Geou-Yarh|Doppler, Heike|Necela, Brian|Krishna, Murli|Crawford, Howard C|Raimondo, Massimo|Storz, Peter
PMID: 23918941
Journal: PLoS One. 2013 Aug 6;8(8):e71367.
Title: Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer.
Author: Koizumi, Mitsuhito|Hiasa, Yoichi|Kumagi, Teru|Yamanishi, Hirofumi|Azemoto, Nobuaki|Kobata, Tetsuji|Matsuura, Bunzo|Abe, Masanori|Onji, Morikazu
PMID: 23940742
Journal: J Biol Chem. 2013 Nov 8;288(45):32517-27.
Title: Proteome variations in pancreatic stellate cells upon stimulation with proinflammatory factors.
Author: Marzoq, Aseel J|Giese, Nathalia|Hoheisel, Jorg D|Alhamdani, Mohamed Saiel Saeed
PMID: 24089530
Journal: PLoS One. 2013 Sep 30;8(9):e75737.
Title: Tumor necrosis factor induces tumor promoting and anti-tumoral effects on pancreatic cancer via TNFR1.
Author: Chopra, Martin|Lang, Isabell|Salzmann, Steffen|Pachel, Christina|Kraus, Sabrina|Bauerlein, Carina A|Brede, Christian|Garrote, Ana-Laura Jordan|Mattenheimer, Katharina|Ritz, Miriam|Schwinn, Stefanie|Graf, Carolin|Schafer, Viktoria|Frantz, Stefan|Einsele, H
PMID: 24098720
Journal: PLoS One. 2013 Oct 11;8(10):e77126.
Title: Digitoflavone inhibits IkappaBalpha kinase and enhances apoptosis induced by TNFalpha through downregulation of expression of nuclear factor kappaB-regulated gene products in human pancreatic cancer cells.
Author: Cai, Xueting|Lu, Wuguang|Yang, Yang|Yang, Jie|Ye, Juan|Gu, Zhenhua|Hu, Chunping|Wang, Xiaoning|Cao, Peng
PMID: 24146961
Journal: Tissue Barriers. 2013 Oct 1;1(4):e25231.
Title: Novel mechanism of cytokine-induced disruption of epithelial barriers: Janus kinase and protein kinase D-dependent downregulation of junction protein expression.
Author: Naydenov, Nayden G|Baranwal, Somesh|Khan, Shadab|Feygin, Alex|Gupta, Pooja|Ivanov, Andrei I
PMID: 24665409
Journal: Psychooncology. 2014 Mar;23(3):339-45.
Title: Depression, cytokines, and pancreatic cancer.
Author: Breitbart, William|Rosenfeld, Barry|Tobias, Kristen|Pessin, Hayley|Ku, Geoffrey Y|Yuan, Jianda|Wolchok, Jedd
PMID: 24136882
Journal: Toxicol Lett. 2014 Jan 3;224(1):157-64.
Title: Apigenin potentiates the growth inhibitory effects by IKK-beta-mediated NF-kappaB activation in pancreatic cancer cells.
Author: Wu, Ding-Guo|Yu, Peng|Li, Jian-Wei|Jiang, Peng|Sun, Jing|Wang, Huai-Zhi|Zhang, Lei-Da|Wen, Ming-Bo|Bie, Ping
PMID: 24148603
Journal: J Gastrointest Cancer. 2014 Mar;45(1):1-11.
Title: Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?
Author: O'Sullivan, Katie E|Reynolds, John V|O'Hanlon, Ciara|O'Sullivan, Jacintha N|Lysaght, Joanne
PMID: 24163144
Journal: Cancer Sci. 2014 Feb;105(2):159-67.
Title: Suppression of Tregs by anti-glucocorticoid induced TNF receptor antibody enhances the antitumor immunity of interferon-alpha gene therapy for pancreatic cancer.
Author: Aida, Kouichirou|Miyakawa, Reina|Suzuki, Koji|Narumi, Kenta|Udagawa, Takeshi|Yamamoto, Yuki|Chikaraishi, Tatsuya|Yoshida, Teruhiko|Aoki, Kazunori
PMID: 24289533
Journal: J Proteome Res. 2014 Mar 7;13(3):1293-306.
Title: Quantitative glycoproteomics analysis reveals changes in N-glycosylation level associated with pancreatic ductal adenocarcinoma.
Author: Pan, Sheng|Chen, Ru|Tamura, Yasuko|Crispin, David A|Lai, Lisa A|May, Damon H|McIntosh, Martin W|Goodlett, David R|Brentnall, Teresa A
PMID: 24471499
Journal: Mol Cancer Res. 2014 May;12(5):670-80.
Title: The multifunctional growth factor midkine promotes proliferation and migration in pancreatic cancer.
Author: Rawnaq, Tamina|Dietrich, Luisa|Wolters-Eisfeld, Gerrit|Uzunoglu, Faik G|Vashist, Yogesh K|Bachmann, Kai|Simon, Ronald|Izbicki, Jakob R|Bockhorn, Maximilian|Gungor, Cenap
PMID: 24567526
Journal: PLoS One. 2014 Mar 20;9(3):e90052.
Title: Contribution of environment and genetics to pancreatic cancer susceptibility.
Author: Hocevar, Barbara A|Kamendulis, Lisa M|Pu, Xinzhu|Perkins, Susan M|Wang, Zheng-Yu|Johnston, Erica L|DeWitt, John M|Li, Lang|Loehrer, Patrick J|Klaunig, James E|Chiorean, E Gabriela
PMID: 24651674
Journal: Front Immunol. 2014 Jun 19;5:269.
Title: Induction of Split Anergy Conditions Natural Killer Cells to Promote Differentiation of Stem Cells through Cell-Cell Contact and Secreted Factors.
Author: Tseng, Han-Ching|Bui, Vickie|Man, Yan-Gao|Cacalano, Nicholas|Jewett, Anahid
PMID: 24995006
Journal: Mol Pharm. 2014 Sep 2;11(9):3112-22.
Title: Targeted nanogel conjugate for improved stability and cellular permeability of curcumin: synthesis, pharmacokinetics, and tumor growth inhibition.
Author: Wei, Xin|Senanayake, Thulani H|Bohling, Anna|Vinogradov, Serguei V
PMID: 25072100
Journal: Med Oncol. 2014 Oct;31(10):241.
Title: Genetic polymorphisms of inflammatory response gene TNF-alpha and its influence on sporadic pancreatic neuroendocrine tumors predisposition risk.
Author: Karakaxas, Dimitrios|Gazouli, Maria|Coker, Ahmet|Agalianos, Christos|Papanikolaou, Ioannis S|Patapis, Pavlos|Liakakos, Theodoros|Dervenis, Christos
PMID: 25213764
Journal: BMC Cancer. 2014 Oct 2;14:738.
Title: Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction.
Author: Peng, Yun-Peng|Zhang, Jing-Jing|Liang, Wen-biao|Tu, Min|Lu, Zi-Peng|Wei, Ji-Shu|Jiang, Kui-Rong|Gao, Wen-Tao|Wu, Jun-Li|Xu, Ze-Kuan|Miao, Yi|Zhu, Yi
PMID: 25274283
Journal: Cell Immunol. 2014 Nov-Dec;292(1-2):65-9.
Title: Pancreatic cancer derived exosomes regulate the expression of TLR4 in dendritic cells via miR-203.
Author: Zhou, Min|Chen, Jionghuang|Zhou, Liangjing|Chen, Wenchao|Ding, Guoping|Cao, Liping
PMID: 25290620
Journal: Gastroenterol Hepatol. 2014 Sep;37 Suppl 3:107-12.
Title: [Pancreas and biliary tract: recent developments].
Author: de-Madaria, Enrique
PMID: 25294273
Journal: Med Sci Monit. 2014 Nov 19;20:2351-7.
Title: Serum adiponectin relates to shortened overall survival in men with squamous cell esophageal cancer treated with preoperative concurrent chemoradiotherapy: a pilot study.
Author: Zemanova, Milada|Stankova, Barbora|Usiakova, Zuzana|Tvrzicka, Eva|Pazdro, Alexandr|Petruzelka, Lubos|Zeman, Miroslav
PMID: 25408239
Journal: PLoS One. 2014 Nov 20;9(11):e113259.
Title: Metabolomics evaluation of serum markers for cachexia and their intra-day variation in patients with advanced pancreatic cancer.
Author: Fujiwara, Yutaka|Kobayashi, Takashi|Chayahara, Naoko|Imamura, Yoshinori|Toyoda, Masanori|Kiyota, Naomi|Mukohara, Toru|Nishiumi, Shin|Azuma, Takeshi|Yoshida, Masaru|Minami, Hironobu
PMID: 25411961
Journal: Nutr Res. 2014 Dec;34(12):1066-74.
Title: Epigallocatechin gallate prevents inflammation by reducing macrophage infiltration and inhibiting tumor necrosis factor-alpha signaling in the pancreas of rats on a high-fat diet.
Author: Cao, Yanli|Bao, Suqing|Yang, Wanli|Zhang, Jin|Li, Lin|Shan, Zhongyan|Teng, Weiping
PMID: 25453543
Journal: Dig Dis Sci. 2015 Apr;60(4):1067-80.
Title: Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer.
Author: Mu, Gang-Gang|Zhang, Ling-Li|Li, Hong-Yan|Liao, Yan|Yu, Hong-Gang
PMID: 25344906
Journal: Cancer Discov. 2015 Jan;5(1):52-63.
Title: Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions.
Author: Liou, Geou-Yarh|Doppler, Heike|Necela, Brian|Edenfield, Brandy|Zhang, Lizhi|Dawson, David W|Storz, Peter
PMID: 25361845
Journal: Anticancer Agents Med Chem. 2015;15(8):1066-77.
Title: 5-Lipoxygenase and cyclooxygenase inhibitory dammarane triterpenoid 1 from Borassus flabellifer seed coat inhibits tumor necrosis factor-alpha secretion in LPSInduced THP-1 human monocytes and induces apoptosis in MIA PaCa-2 pancreatic cancer cells.
Author: Yarla, Nagendra Sastry|Azad, Rajaram|Basha, Mahaboob|Rajack, Abdul|Kaladhar, D S V G K|Allam, Bharat Kumar|Pragada, Rajeswara Rao|Singh, Krishna Nand|K, Sunanda Kumari|Pallu, Reddanna|Parimi, Umadevi|Bishayee, Anupam|Duddukuri, Govinda Rao
PMID: 25642980
Journal: Med Hypotheses. 2015 Mar;84(3):231-7.
Title: Measuring sickness behavior in the context of pancreatic cancer.
Author: Tobias, Kristen|Rosenfeld, Barry|Pessin, Hayley|Breitbart, William
PMID: 25659492
Journal: Int J Mol Med. 2015 Jun;35(6):1773-8.
Title: Suppressive effects of exogenous regucalcin on the proliferation of human pancreatic cancer MIA PaCa-2 cells in vitro.
Author: Yamaguchi, Masayoshi|Murata, Tomiyasu
PMID: 25847529
Journal: Tumour Biol. 2015 Sep;36(10):7557-68.
Title: Orthotopic inflammation-related pancreatic carcinogenesis in a wild-type mouse induced by combined application of caerulein and dimethylbenzanthracene.
Author: Liang, Chen|Wang, Zhen|Wu, Li|Wang, Chen|Yu, Bao-Hua|Yao, Xiu-Zhong|Wang, Xiao-Lin|Li, Ying-Yi
PMID: 25916208
Journal: Oncoimmunology. 2015 Jan 22;4(4):e1000083.
Title: CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4(+) T cells in pancreatic cancer development.
Author: Goebel, Lisa|Grage-Griebenow, Evelin|Gorys, Artur|Helm, Ole|Genrich, Geeske|Lenk, Lennart|Wesch, Daniela|Ungefroren, Hendrik|Freitag-Wolf, Sandra|Sipos, Bence|Rocken, Christoph|Schafer, Heiner|Sebens, Susanne
PMID: 26137395
Journal: Eur J Med Chem. 2015 Sep 18;102:530-9.
Title: Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.
Author: Sociali, Giovanna|Galeno, Lauretta|Parenti, Marco Daniele|Grozio, Alessia|Bauer, Inga|Passalacqua, Mario|Boero, Silvia|Donadini, Alessandra|Millo, Enrico|Bellotti, Marta|Sturla, Laura|Damonte, Patrizia|Puddu, Alessandra|Ferroni, Claudia|Varchi, Greta|Fran
PMID: 26310895
Journal: Oncotarget. 2015 Sep 29;6(29):26895-908.
Title: A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
Author: Moon, Jai-Hee|Shin, Jae-Sik|Hong, Seung-Woo|Jung, Soo-A|Hwang, Ih-Yeon|Kim, Jeong Hee|Choi, Eun Kyoung|Ha, Seung-Hee|Kim, Jin-Sun|Kim, Kyoung-Mok|Hong, Dae-Won|Kim, Daejin|Kim, Yeong Seok|Kim, Jeong Eun|Kim, Kyu-Pyo|Hong, Yong Sang|Choi, Eun Kyung|Lee, Ju
PMID: 26314849
Journal: Biomol Ther (Seoul). 2015 Sep;23(5):428-33.
Title: Acetylshikonin Inhibits Human Pancreatic PANC-1 Cancer Cell Proliferation by Suppressing the NF-kappaB Activity.
Author: Cho, Seok-Cheol|Choi, Bu Young
PMID: 26336582
Journal: Eur J Surg Oncol. 2015 Nov;41(11):1508-14.
Title: Prognostic nutritional index predicts survival and correlates with systemic inflammatory response in advanced pancreatic cancer.
Author: Geng, Y|Qi, Q|Sun, M|Chen, H|Wang, P|Chen, Z
PMID: 26343824
Journal: Nat Med. 2015 Nov;21(11):1337-43.
Title: Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.
Author: Alam, Muhammad S|Gaida, Matthias M|Bergmann, Frank|Lasitschka, Felix|Giese, Thomas|Giese, Nathalia A|Hackert, Thilo|Hinz, Ulf|Hussain, S Perwez|Kozlov, Serguei V|Ashwell, Jonathan D
PMID: 26479921
Journal: Front Immunol. 2015 Dec 2;6:576.
Title: Augmented IFN-gamma and TNF-alpha Induced by Probiotic Bacteria in NK Cells Mediate Differentiation of Stem-Like Tumors Leading to Inhibition of Tumor Growth and Reduction in Inflammatory Cytokine Release; Regulation by IL-10.
Author: Bui, Vickie T|Tseng, Han-Ching|Kozlowska, Anna|Maung, Phyu Ou|Kaur, Kawaljit|Topchyan, Paytsar|Jewett, Anahid
PMID: 26697005
Journal: Int J Cancer. 2016 Mar 1;138(5):1118-28.
Title: Chronic inflammation and risk of colorectal and other obesity-related cancers: The health, aging and body composition study.
Author: Izano, Monika|Wei, Esther K|Tai, Caroline|Swede, Helen|Gregorich, Steven|Harris, Tamara B|Klepin, Heidi|Satterfield, Suzanne|Murphy, Rachel|Newman, Anne B|Rubin, Susan M|Braithwaite, Dejana
PMID: 26413860
Journal: Dig Dis Sci. 2016 Apr;61(4):1121-9.
Title: Subclinical Inflammation and Endothelial Dysfunction in Patients with Chronic Pancreatitis and Newly Diagnosed Pancreatic Cancer.
Author: Gasiorowska, A|Talar-Wojnarowska, R|Kaczka, A|Borkowska, A|Czupryniak, L|Malecka-Panas, E
PMID: 26597191
Journal: J Immunother. 2016 Feb-Mar;39(2):81-9.
Title: Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer.
Author: Meng, Qingda|Liu, Zhenjiang|Rangelova, Elena|Poiret, Thomas|Ambati, Aditya|Rane, Lalit|Xie, Shanshan|Verbeke, Caroline|Dodoo, Ernest|Del Chiaro, Marco|Lohr, Matthias|Segersvard, Ralf|Maeurer, Markus J
PMID: 26849077
Journal: Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2466-71.
Title: AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas.
Author: Smith, Tracey L|Yuan, Ziqiang|Cardo-Vila, Marina|Sanchez Claros, Carmen|Adem, Asha|Cui, Min-Hui|Branch, Craig A|Gelovani, Juri G|Libutti, Steven K|Sidman, Richard L|Pasqualini, Renata|Arap, Wadih
PMID: 26884209
Journal: Oncol Lett. 2016 Mar;11(3):1835-1840.
Title: Expression of tumor necrosis factor-alpha-induced protein 8 in stage III gastric cancer and the correlation with DcR3 and ERK1/2.
Author: Hu, Ruyi|Liu, Wenming|Qiu, Xingfeng|Lin, Zhenghe|Xie, Yan|Hong, Xingya|Paerhati, Reyila|Qi, Zhongquan|Zhuang, Guohong|Liu, Zhongchen
PMID: 26998086
Journal: Int J Mol Sci. 2016 Mar 30;17(4):474.
Title: Thymoquinone Modulates Blood Coagulation in Vitro via Its Effects on Inflammatory and Coagulation Pathways.
Author: Muralidharan-Chari, Vandhana|Kim, Jaehan|Abuawad, Ahlam|Naeem, Mubeena|Cui, Huadong|Mousa, Shaker A
PMID: 27043539
Journal: J Nutr Biochem. 2016 May;31:77-87.
Title: Small molecule tolfenamic acid and dietary spice curcumin treatment enhances antiproliferative effect in pancreatic cancer cells via suppressing Sp1, disrupting NF-kB translocation to nucleus and cell cycle phase distribution.
Author: Basha, Riyaz|Connelly, Sarah F|Sankpal, Umesh T|Nagaraju, Ganji Purnachandra|Patel, Hassaan|Vishwanatha, Jamboor K|Shelake, Sagar|Tabor-Simecka, Leslie|Shoji, Mamoru|Simecka, Jerry W|El-Rayes, Bassel
PMID: 27133426
Journal: Int J Radiat Biol. 2016 Aug;92(8):427-33.
Title: Irradiated human endothelial progenitor cells induce bystander killing in human non-small cell lung and pancreatic cancer cells.
Author: Turchan, William T|Shapiro, Ronald H|Sevigny, Garrett V|Chin-Sinex, Helen|Pruden, Benjamin|Mendonca, Marc S
PMID: 27258472
Journal: Cancer Lett. 2016 Sep 28;380(1):31-8.
Title: Smac mimetic triggers necroptosis in pancreatic carcinoma cells when caspase activation is blocked.
Author: Hannes, Sabine|Abhari, Behnaz Ahangarian|Fulda, Simone
PMID: 27267809
Journal: Mol Med Rep. 2016 Oct;14(4):3627-33.
Title: Activated leukocyte cell adhesion molecule regulates the interaction between pancreatic cancer cells and stellate cells.
Author: Zhang, Wei-Wei|Zhan, Shu-Hui|Geng, Chang-Xin|Sun, Xin|Erkan, Mert|Kleeff, Jorg|Xie, Xiang-Jun
PMID: 27573419
Journal: Oncotarget. 2016 Dec 6;7(49):81110-81122.
Title: Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma.
Author: Zhao, Xianda|Fan, Wei|Xu, Zhigao|Chen, Honglei|He, Yuyu|Yang, Gui|Yang, Gang|Hu, Hanning|Tang, Shihui|Wang, Ping|Zhang, Zheng|Xu, Peipei|Yu, Mingxia
PMID: 27835602
Journal: Crit Rev Oncol Hematol. 2016 Dec;108:146-153.
Title: Hyperglycemia, tumorigenesis, and chronic inflammation.
Author: Chang, Shu-Chun|Yang, Wei-Chung Vivian
PMID: 27931833
Journal: Cancer Res. 2017 Feb 1;77(3):719-731.
Title: Targeting Tumor-Associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors.
Author: Miao, Lei|Liu, Qi|Lin, C Michael|Luo, Cong|Wang, Yuhua|Liu, Lina|Yin, Weiyan|Hu, Shihao|Kim, William Y|Huang, Leaf
PMID: 27864344
Journal: Support Care Cancer. 2017 Jun;25(6):1809-1817.
Title: A predictive model of inflammatory markers and patient-reported symptoms for cachexia in newly diagnosed pancreatic cancer patients.
Author: Fogelman, David R|Morris, J|Xiao, L|Hassan, M|Vadhan, S|Overman, M|Javle, S|Shroff, R|Varadhachary, G|Wolff, R|Vence, L|Maitra, A|Cleeland, C|Wang, X S
PMID: 28111717
Journal: World J Gastroenterol. 2017 Feb 7;23(5):817-829.
Title: Dendritic cells engineered to secrete anti-DcR3 antibody augment cytotoxic T lymphocyte response against pancreatic cancer in vitro.
Author: Chen, Jiang|Guo, Xiao-Zhong|Li, Hong-Yu|Zhao, Jia-Jun|Xu, Wen-Da
PMID: 28223726
Journal: Oncol Lett. 2017 Mar;13(3):1939-1943.
Title: Effect of cigarette smoke exposure and mutant Kras overexpression on pancreatic cell proliferation.
Author: Glauert, Howard P|Elliott, R Scott|Han, Sung Gu|Athey, Mark|Lee, Eun Y|Gairola, C Gary
PMID: 28454347
Journal: J Biol Chem. 2017 Jun 23;292(25):10390-10397.
Title: The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis-inducing ligand.
Author: Yang, Shan-Zhong|Xu, Fei|Zhou, Tong|Zhao, Xinyang|McDonald, Jay M|Chen, Yabing
PMID: 28476883
Journal: BMC Musculoskelet Disord. 2017 May 8;18(1):182.
Title: Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ss or TNF-alpha.
Author: Gruber, Helen E|Ingram, Jane A|Hoelscher, Gretchen L|Marrero, Emilio|Hanley, Edward N Jr
PMID: 28482827
Journal: Biochem Biophys Res Commun. 2017 Jun 24;488(2):425-431.
Title: miR-142-5p regulates tumor cell PD-L1 expression and enhances anti-tumor immunity.
Author: Jia, Long|Xi, Qing|Wang, Huafeng|Zhang, Zimu|Liu, Hongkun|Cheng, Yingnan|Guo, Xiangdong|Zhang, Jieyou|Zhang, Qi|Zhang, Lijuan|Xue, Zhenyi|Li, Yan|Da, Yurong|Zhao, Peng|Zhang, Rongxin
PMID: 28511795
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2017 Oct;390(10):1061-1071.
Title: Anticancer activity of salicin and fenofibrate.
Author: Sabaa, Marwa|ELFayoumi, Hassan M|Elshazly, Shimaa|Youns, Mahmoud|Barakat, Waleed
PMID: 28733879
Journal: J Clin Invest. 2017 Oct 2;127(10):3796-3809.
Title: NF-kappaB regulates GDF-15 to suppress macrophage surveillance during early tumor development.
Author: Ratnam, Nivedita M|Peterson, Jennifer M|Talbert, Erin E|Ladner, Katherine J|Rajasekera, Priyani V|Schmidt, Carl R|Dillhoff, Mary E|Swanson, Benjamin J|Haverick, Ericka|Kladney, Raleigh D|Williams, Terence M|Leone, Gustavo W|Wang, David J|Guttridge, Denis
PMID: 28891811
Journal: Bioorg Med Chem. 2017 Oct 15;25(20):5849-5858.
Title: SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.
Author: Damonte, Patrizia|Sociali, Giovanna|Parenti, Marco Daniele|Soncini, Debora|Bauer, Inga|Boero, Silvia|Grozio, Alessia|Holtey, Maria von|Piacente, Francesco|Becherini, Pamela|Sanguineti, Roberta|Salis, Annalisa|Damonte, Gianluca|Cea, Michele|Murone, Maximil
PMID: 28958848
Journal: Exp Cell Res. 2017 Dec 1;361(1):39-45.
Title: CXCR5(+) CD8(+) T cells potently infiltrate pancreatic tumors and present high functionality.
Author: Bai, Minghui|Zheng, Youwei|Liu, Haichao|Su, Baowei|Zhan, Yong|He, Hua
PMID: 28965867
Journal: Pancreatology. 2017 Nov - Dec;17(6):962-966.
Title: Immunomodulation after radiofrequency ablation of locally advanced pancreatic cancer by monitoring the immune response in 10 patients.
Author: Giardino, Alessandro|Innamorati, Giulio|Ugel, Stefano|Perbellini, Omar|Girelli, Roberto|Frigerio, Isabella|Regi, Paolo|Scopelliti, Filippo|Butturini, Giovanni|Paiella, Salvatore|Bacchion, Matilde|Bassi, Claudio
PMID: 29037917
Journal: Oncotarget. 2017 Aug 17;8(42):72315-72323.
Title: Postoperative course and prognostic value of circulating angiogenic cytokines after pancreatic cancer resection.
Author: Yang, Cui|Bork, Ulrich|Scholch, Sebastian|Kulu, Yakup|Kaderali, Lars|Bolstorff, Uta L|Kahlert, Christoph|Weitz, Jurgen|Rahbari, Nuh N|Reissfelder, Christoph
PMID: 29069789
Journal: Biomed Res Int. 2017;2017:2979307.
Title: The Diagnostic Roles of Cytokines in Hepatobiliary Cancers.
Author: Koca, Yavuz Savas|Bulbul, Mahmut|Barut, Ibrahim
PMID: 29410961
Journal: FASEB J. 2018 Mar;32(3):1170-1183.
Title: GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells.
Author: Wiley, Shu Z|Sriram, Krishna|Liang, Wenjing|Chang, Sarah E|French, Randall|McCann, Thalia|Sicklick, Jason|Nishihara, Hiroshi|Lowy, Andrew M|Insel, Paul A
PMID: 29092903
Journal: Cancer Biol Ther. 2018 Apr 3;19(4):296-305.
Title: The predictive value and role of stromal tumor-infiltrating lymphocytes in pancreatic ductal adenocarcinoma (PDAC).
Author: Lianyuan, Tao|Dianrong, Xiu|Chunhui, Yuan|Zhaolai, Ma|Bin, Jiang
PMID: 29313457
Journal: BMC Cancer. 2018 Apr 2;18(1):360.
Title: The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells.
Author: Wang, Feng|Liu, Hongyi|Hu, Lijuan|Liu, Yunfei|Duan, Yijie|Cui, Rui|Tian, Wencong
PMID: 29609556
Journal: JCI Insight. 2018 Apr 5;3(7). pii: 99573.
Title: Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses.
Author: Watanabe, Keisuke|Luo, Yanping|Da, Tong|Guedan, Sonia|Ruella, Marco|Scholler, John|Keith, Brian|Young, Regina M|Engels, Boris|Sorsa, Suvi|Siurala, Mikko|Havunen, Riikka|Tahtinen, Siri|Hemminki, Akseli|June, Carl H
PMID: 29618658
Journal: Bull Exp Biol Med. 2018 Jun;165(2):259-263.
Title: Transforming Growth Factor-beta and Tumor Necrosis Factor-alpha Reduce the Sensitivity of MiaPaCa2 Pancreatic Cancer Cells to Lysis by NK Cells.
Author: Ostapchuk, E O|Kali, A|Belyaev, N N
PMID: 29926278
Journal: J Clin Med. 2018 Jul 13;7(7). pii: jcm7070175.
Title: Differential Roles of Tumor Necrosis Factor Ligand Superfamily Members as Biomarkers in Pancreatic Cancer.
Author: Pombeiro, Ines|Loosen, Sven H|Roy, Sanchari|Schueller, Florian|Niewenhuisen, Lukas|Luedde, Mark|Vucur, Mihael|Tacke, Frank|Binnebosel, Marcel|Schoening, Wenzel|Trautwein, Christian|Luedde, Tom|Neumann, Ulf Peter|Roderburg, Christoph
PMID: 30011858
Journal: Front Immunol. 2018 Aug 15;9:1844.
Title: Human Surfactant Protein D Suppresses Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells by Downregulating TGF-beta.
Author: Kaur, Anuvinder|Riaz, Muhammad Suleman|Singh, Shiv K|Kishore, Uday
PMID: 30158928
Journal: Oncotarget. 2018 Aug 3;9(60):31771-31786.
Title: Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells.
Author: Knaack, Hendrike|Lenk, Lennart|Philipp, Lisa-Marie|Miarka, Lauritz|Rahn, Sascha|Viol, Fabrice|Hauser, Charlotte|Egberts, Jan-Hendrik|Gundlach, Jan-Paul|Will, Olga|Tiwari, Sanjay|Mikulits, Wolfgang|Schumacher, Udo|Hengstler, Jan G|Sebens, Susanne
PMID: 30167093
Journal: Cancer Immunol Immunother. 2018 Aug 22. pii: 10.1007/s00262-018-2235-8.
Title: Anergic natural killer cells educated by tumor cells are associated with a poor prognosis in patients with advanced pancreatic ductal adenocarcinoma.
Author: Yang, Chao|Cheng, He|Zhang, Yiyin|Fan, Kun|Luo, Guopei|Fan, Zhiyao|Huang, Qiuyi|Lu, Yu|Jin, Kaizhou|Wang, Zhengshi|Yu, Xianjun|Liu, Chen
PMID: 30167864
Journal: Cancer Discov. 2018 Sep 5. pii: 2159-8290.CD-18-0046.
Title: Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness.
Author: Renz, Bernhard W|Tanaka, Takayuki|Sunagawa, Masaki|Takahashi, Ryota|Jiang, Zhengyu|Macchini, Marina|Dantes, Zahra|Valenti, Giovanni|White, Ruth A|Middelhoff, Moritz A|Ilmer, Matthias|Oberstein, Paul E|Angele, Martin K|Deng, Huan|Hayakawa, Yoku|Westphalen,
PMID: 30185628