Primary Site >> Colorectal Cancer

Gene >> TLR8

Journal: Mol Cancer Ther. 2010 Jun;9(6):1788-97.
Title: Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8.
Author: Wang, Daqing|Precopio, Melissa|Lan, Tao|Yu, Dong|Tang, Jimmy X|Kandimalla, Ekambar R|Agrawal, Sudhir
PMID: 20515950
Journal: Eur J Cancer. 2010 Oct;46(15):2849-57.
Title: Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression.
Author: Grimm, Martin|Kim, Mia|Rosenwald, Andreas|Heemann, Uwe|Germer, Christoph-Thomas|Waaga-Gasser, Ana Maria|Gasser, Martin
PMID: 20728343
Journal: Int J Mol Sci. 2014 Dec 24;16(1):159-77.
Title: Upregulation of TLRs and IL-6 as a marker in human colorectal cancer.
Author: Lu, Chien-Chang|Kuo, Hsing-Chun|Wang, Feng-Sheng|Jou, Ming-Huey|Lee, Ko-Chao|Chuang, Jiin-Haur
PMID: 25547486
Journal: Immunopharmacol Immunotoxicol. 2017 Aug;39(4):199-210.
Title: The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation.
Author: Blom, Kristin|Senkowski, Wojciech|Jarvius, Malin|Berglund, Malin|Rubin, Jenny|Lenhammar, Lena|Parrow, Vendela|Andersson, Claes|Loskog, Angelica|Fryknas, Marten|Nygren, Peter|Larsson, Rolf
PMID: 28472897