Primary Site >> Colorectal Cancer

Gene >> TLR8

  • 2010
  • 2014
  • 2017
Ref: Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8.
PMID: 20515950
Ref: Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression.
PMID: 20728343
Ref: Upregulation of TLRs and IL-6 as a marker in human colorectal cancer.
PMID: 25547486
Ref: The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation.
PMID: 28472897