Primary Site >> Pancreatic Cancer
Gene >> TLR4
| 1. | |||||||||||
| Journal: | J Surg Oncol. 2009 Dec 15;100(8):725-31. | ||||||||||
| Title: | Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway. | ||||||||||
| Author: | Ikebe, Mio|Kitaura, Yoshiki|Nakamura, Masafumi|Tanaka, Haruo|Yamasaki, Akio|Nagai, Shuntaro|Wada, Junji|Yanai, Kosuke|Koga, Kenichiro|Sato, Norihiro|Kubo, Makoto|Tanaka, Masao|Onishi, Hideya|Katano, Mitsuo | ||||||||||
| PMID: | 19722233 | ||||||||||
| 2. | |||||||||||
| Journal: | Pancreatology. 2010;10(2-3):114-8. | ||||||||||
| Title: | Primers on molecular pathways: lipopolysaccharide signaling - potential role in pancreatitis and pancreatic cancer. | ||||||||||
| Author: | Del Pozo, Jose L | ||||||||||
| PMID: | 20460943 | ||||||||||
| 3. | |||||||||||
| Journal: | World J Gastroenterol. 2010 Jun 21;16(23):2881-8. | ||||||||||
| Title: | Expression and significance of TLR4 and HIF-1alpha in pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Zhang, Jian-Jun|Wu, He-Shui|Wang, Lin|Tian, Yuan|Zhang, Jing-Hui|Wu, Hai-Long | ||||||||||
| PMID: | 20556833 | ||||||||||
| 4. | |||||||||||
| Journal: | IDrugs. 2010 Jul;13(7):424-6. | ||||||||||
| Title: | Digestive Disease Week 2010. Turning Science into Medicine--part 2. | ||||||||||
| Author: | Hodgkinson, Lisa | ||||||||||
| PMID: | 20582861 | ||||||||||
| 5. | |||||||||||
| Journal: | Rare Tumors. 2010 Sep 30;2(3):e52. | ||||||||||
| Title: | Pancreatic Cancer: a rare tumor with a devastating health toll. | ||||||||||
| Author: | Fleshman, Julie | ||||||||||
| PMID: | 21139967 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer. 2012 Feb 15;118(4):1119-29. | ||||||||||
| Title: | Cost-effectiveness of modern radiotherapy techniques in locally advanced pancreatic cancer. | ||||||||||
| Author: | Murphy, James D|Chang, Daniel T|Abelson, Jon|Daly, Megan E|Yeung, Heidi N|Nelson, Lorene M|Koong, Albert C | ||||||||||
| PMID: | 21773972 | ||||||||||
| 7. | |||||||||||
| Journal: | Pancreatology. 2012 Mar-Apr;12(2):170-8. | ||||||||||
| Title: | Hypoxia-inducible factor-1 up-regulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions. | ||||||||||
| Author: | Fan, Ping|Zhang, Jian-Jun|Wang, Bo|Wu, Han-Qing|Zhou, Si-Xing|Wang, Chun-You|Zhang, Jing-Hui|Tian, Yuan|Wu, He-Shui | ||||||||||
| PMID: | 22487528 | ||||||||||
| 8. | |||||||||||
| Journal: | J Exp Med. 2012 Aug 27;209(9):1671-87. | ||||||||||
| Title: | MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. | ||||||||||
| Author: | Ochi, Atsuo|Nguyen, Andrew H|Bedrosian, Andrea S|Mushlin, Harry M|Zarbakhsh, Saman|Barilla, Rocky|Zambirinis, Constantinos P|Fallon, Nina C|Rehman, Adeel|Pylayeva-Gupta, Yuliya|Badar, Sana|Hajdu, Cristina H|Frey, Alan B|Bar-Sagi, Dafna|Miller, George | ||||||||||
| PMID: | 22908323 | ||||||||||
| 9. | |||||||||||
| Journal: | Pancreatology. 2012 Nov-Dec;12(6):467-74. | ||||||||||
| Title: | Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells. | ||||||||||
| Author: | Rosendahl, Ann H|Sun, Chen|Wu, DeQuan|Andersson, Roland | ||||||||||
| PMID: | 23217280 | ||||||||||
| 10. | |||||||||||
| Journal: | J Immunol. 2013 Feb 15;190(4):1859-72. | ||||||||||
| Title: | Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-gamma and lipopolysaccharide in human pancreatic cancer cell lines. | ||||||||||
| Author: | Wu, Yongzhong|Lu, Jiamo|Antony, Smitha|Juhasz, Agnes|Liu, Han|Jiang, Guojian|Meitzler, Jennifer L|Hollingshead, Melinda|Haines, Diana C|Butcher, Donna|Roy, Krishnendu|Doroshow, James H | ||||||||||
| PMID: | 23296709 | ||||||||||
| 11. | |||||||||||
| Journal: | Lab Invest. 2013 Jul;93(7):844-54. | ||||||||||
| Title: | M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway. | ||||||||||
| Author: | Liu, Chao-Ying|Xu, Juan-Ying|Shi, Xiao-Yan|Huang, Wei|Ruan, Ting-Yan|Xie, Ping|Ding, Jun-Li | ||||||||||
| PMID: | 23752129 | ||||||||||
| 12. | |||||||||||
| Journal: | Multidiscip Respir Med. 2013 Oct 5;8(1):65. | ||||||||||
| Title: | CD24+/CD38- as new prognostic marker for non-small cell lung cancer. | ||||||||||
| Author: | Karimi-Busheri, Feridoun|Rasouli-Nia, Aghdass|Zadorozhny, Victoria|Fakhrai, Habib | ||||||||||
| PMID: | 24094028 | ||||||||||
| 13. | |||||||||||
| Journal: | Onco Targets Ther. 2013 Nov 5;6:1573-87. | ||||||||||
| Title: | Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers. | ||||||||||
| Author: | Mai, Chun Wai|Kang, Yew Beng|Pichika, Mallikarjuna Rao | ||||||||||
| PMID: | 24235843 | ||||||||||
| 14. | |||||||||||
| Journal: | Nutr Res. 2014 Dec;34(12):1066-74. | ||||||||||
| Title: | Epigallocatechin gallate prevents inflammation by reducing macrophage infiltration and inhibiting tumor necrosis factor-alpha signaling in the pancreas of rats on a high-fat diet. | ||||||||||
| Author: | Cao, Yanli|Bao, Suqing|Yang, Wanli|Zhang, Jin|Li, Lin|Shan, Zhongyan|Teng, Weiping | ||||||||||
| PMID: | 25453543 | ||||||||||
| 15. | |||||||||||
| Journal: | Cent Eur J Immunol. 2014;39(4):498-507. | ||||||||||
| Title: | Gene expression disorders of innate antibacterial signaling pathway in pancreatic cancer patients: implications for leukocyte dysfunction and tumor progression. | ||||||||||
| Author: | Slotwinski, Robert|Dabrowska, Aleksandra|Lech, Gustaw|Slodkowski, Maciej|Slotwinska, Sylwia M | ||||||||||
| PMID: | 26155170 | ||||||||||
| 16. | |||||||||||
| Journal: | Cell Immunol. 2014 Nov-Dec;292(1-2):65-9. | ||||||||||
| Title: | Pancreatic cancer derived exosomes regulate the expression of TLR4 in dendritic cells via miR-203. | ||||||||||
| Author: | Zhou, Min|Chen, Jionghuang|Zhou, Liangjing|Chen, Wenchao|Ding, Guoping|Cao, Liping | ||||||||||
| PMID: | 25290620 | ||||||||||
| 17. | |||||||||||
| Journal: | Dig Dis Sci. 2014 Jul;59(7):1452-60. | ||||||||||
| Title: | LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4. | ||||||||||
| Author: | Liu, Jianhui|Xu, Dong|Wang, Qingguang|Zheng, Datong|Jiang, Xiuqin|Xu, Lijian | ||||||||||
| PMID: | 24532253 | ||||||||||
| 18. | |||||||||||
| Journal: | AAPS J. 2014 Mar;16(2):246-57. | ||||||||||
| Title: | Antitumor activity of gemcitabine can be potentiated in pancreatic cancer through modulation of TLR4/NF-kappaB signaling by 6-shogaol. | ||||||||||
| Author: | Zhou, Ling|Qi, Lianwen|Jiang, Lifeng|Zhou, Ping|Ma, Jiang|Xu, Xiaojun|Li, Ping | ||||||||||
| PMID: | 24424498 | ||||||||||
| 19. | |||||||||||
| Journal: | World J Gastroenterol. 2014 May 21;20(19):5808-17. | ||||||||||
| Title: | Intervention on toll-like receptors in pancreatic cancer. | ||||||||||
| Author: | Vaz, Juan|Andersson, Roland | ||||||||||
| PMID: | 24914341 | ||||||||||
| 20. | |||||||||||
| Journal: | Free Radic Res. 2015;49(11):1371-83. | ||||||||||
| Title: | Inflammation-induced ROS generation causes pancreatic cell death through modulation of Nrf2/NF-kappaB and SAPK/JNK pathway. | ||||||||||
| Author: | Choudhury, S|Ghosh, S|Gupta, P|Mukherjee, S|Chattopadhyay, S | ||||||||||
| PMID: | 26189548 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 29;6(29):27751-62. | ||||||||||
| Title: | Pancreatic adenocarcinoma upregulated factor serves as adjuvant by activating dendritic cells through stimulation of TLR4. | ||||||||||
| Author: | Kang, Tae Heung|Kim, Young Seob|Kim, Seokho|Yang, Benjamin|Lee, Je-Jung|Lee, Hyun-Ju|Lee, Jaemin|Jung, In Duk|Han, Hee Dong|Lee, Seung-Hyun|Koh, Sang Seok|Wu, T-C|Park, Yeong-Min | ||||||||||
| PMID: | 26336989 | ||||||||||
| 22. | |||||||||||
| Journal: | J Exp Med. 2015 Nov 16;212(12):1988. | ||||||||||
| Title: | Pancreatic cancer takes its Toll. | ||||||||||
| Author: | Mazur, Pawel K|Sage, Julien | ||||||||||
| PMID: | 26573583 | ||||||||||
| 23. | |||||||||||
| Journal: | Int J Mol Sci. 2016 Dec 8;17(12). pii: ijms17122060. | ||||||||||
| Title: | Toll Like Receptor 2, 4, and 9 Signaling Promotes Autoregulative Tumor Cell Growth and VEGF/PDGF Expression in Human Pancreatic Cancer. | ||||||||||
| Author: | Grimmig, Tanja|Moench, Romana|Kreckel, Jennifer|Haack, Stephanie|Rueckert, Felix|Rehder, Roberta|Tripathi, Sudipta|Ribas, Carmen|Chandraker, Anil|Germer, Christoph T|Gasser, Martin|Waaga-Gasser, Ana Maria | ||||||||||
| PMID: | 27941651 | ||||||||||
| 24. | |||||||||||
| Journal: | Cent Eur J Immunol. 2016;41(4):404-418. | ||||||||||
| Title: | Dysregulation of signaling pathways associated with innate antibacterial immunity in patients with pancreatic cancer. | ||||||||||
| Author: | Slotwinski, Robert|Slotwinska, Sylwia Malgorzata | ||||||||||
| PMID: | 28450804 | ||||||||||
| 25. | |||||||||||
| Journal: | Sci Rep. 2016 Aug 11;6:31490. | ||||||||||
| Title: | CD14/TLR4 priming potentially recalibrates and exerts anti-tumor efficacy in tumor associated macrophages in a mouse model of pancreatic carcinoma. | ||||||||||
| Author: | Prakash, Hridayesh|Nadella, Vinod|Singh, Sandhya|Schmitz-Winnenthal, Hubertus | ||||||||||
| PMID: | 27511884 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 9;7(32):51840-51853. | ||||||||||
| Title: | Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer. | ||||||||||
| Author: | Song, Jinhoi|Lee, Jaemin|Kim, Jinsil|Jo, Seongyea|Kim, Yeon Jeong|Baek, Ji Eun|Kwon, Eun-Soo|Lee, Kwang-Pyo|Yang, Siyoung|Kwon, Ki-Sun|Kim, Dong-Uk|Kang, Tae Heung|Park, Yun-Yong|Chang, Suhwan|Cho, Hee Jun|Kim, Song Cheol|Koh, Sang Seok|Kim, Seokho | ||||||||||
| PMID: | 27322081 | ||||||||||
| 27. | |||||||||||
| Journal: | Sci Rep. 2016 Jun 8;6:27528. | ||||||||||
| Title: | Soluble B7-H3 promotes the invasion and metastasis of pancreatic carcinoma cells through the TLR4/NF-kappaB pathway. | ||||||||||
| Author: | Xie, Chao|Liu, Danqing|Chen, Qijun|Yang, Chong|Wang, Bo|Wu, Heshui | ||||||||||
| PMID: | 27273624 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Immunol Res. 2017 Mar;5(3):182-190. | ||||||||||
| Title: | Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer. | ||||||||||
| Author: | Cullis, Jane|Siolas, Despina|Avanzi, Antonina|Barui, Sugata|Maitra, Anirban|Bar-Sagi, Dafna | ||||||||||
| PMID: | 28108630 | ||||||||||
| 29. | |||||||||||
| Journal: | Virchows Arch. 2017 Apr;470(4):401-410. | ||||||||||
| Title: | High toll-like receptor (TLR) 9 expression is associated with better prognosis in surgically treated pancreatic cancer patients. | ||||||||||
| Author: | Leppanen, Joni|Helminen, Olli|Huhta, Heikki|Kauppila, Joonas H|Isohookana, Joel|Haapasaari, Kirsi-Maria|Lehenkari, Petri|Saarnio, Juha|Karttunen, Tuomo J | ||||||||||
| PMID: | 28191612 | ||||||||||
| 30. | |||||||||||
| Journal: | J Cancer. 2018 Jan 5;9(3):614-628. | ||||||||||
| Title: | The role of cancer-associated fibroblast MRC-5 in pancreatic cancer. | ||||||||||
| Author: | Ding, Song-Ming|Lu, Ai-Li|Zhang, Wu|Zhou, Lin|Xie, Hai-Yang|Zheng, Shu-Sen|Li, Qi-Yong | ||||||||||
| PMID: | 29483967 | ||||||||||
| 31. | |||||||||||
| Journal: | Sci Rep. 2018 Aug 15;8(1):12161. | ||||||||||
| Title: | Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer. | ||||||||||
| Author: | Choi, Chel Hun|Kang, Tae Heung|Song, Joon Seon|Kim, Young Seob|Chung, Eun Joo|Ylaya, Kris|Kim, Seokho|Koh, Sang Seok|Chung, Joon-Yong|Kim, Jae-Hoon|Hewitt, Stephen M | ||||||||||
| PMID: | 30111860 | ||||||||||
| 32. | |||||||||||
| Journal: | Tumour Biol. 2018 Sep;40(9):1010428318801188. | ||||||||||
| Title: | Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer. | ||||||||||
| Author: | Lanki, Mira A|Seppanen, Hanna E|Mustonen, Harri K|Bockelman, Camilla|Juuti, Anne T|Hagstrom, Jaana K|Haglund, Caj H | ||||||||||
| PMID: | 30246618 | ||||||||||
| 33. | |||||||||||
| Journal: | J Cell Physiol. 2018 Oct 14. | ||||||||||
| Title: | Resistin effects on pancreatic cancer progression and chemoresistance are mediated through its receptors CAP1 and TLR4. | ||||||||||
| Author: | Zhang, Min|Yan, Li|Wang, Gui-Jie|Jin, Ronghui | ||||||||||
| PMID: | 30317640 | ||||||||||
| 34. | |||||||||||
| Journal: | APMIS. 2018 Nov;126(11):852-863. | ||||||||||
| Title: | Toll-like receptors 2, 4 and 9 and hypoxia markers HIF-1alpha and CAIX in pancreatic intraepithelial neoplasia. | ||||||||||
| Author: | Leppanen, Joni|Helminen, Olli|Huhta, Heikki|Kauppila, Joonas H|Isohookana, Joel|Haapasaari, Kirsi-Maria|Karihtala, Peeter|Parkkila, Seppo|Saarnio, Juha|Lehenkari, Petri P|Karttunen, Tuomo J | ||||||||||
| PMID: | 30357962 | ||||||||||