Primary Site >> Pancreatic Cancer
Gene >> TLR4
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Ref: Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway. PMID: 19722233 |
Ref: Primers on molecular pathways: lipopolysaccharide signaling - potential role in pancreatitis and pancreatic cancer. PMID: 20460943 Ref: Expression and significance of TLR4 and HIF-1alpha in pancreatic ductal adenocarcinoma. PMID: 20556833 Ref: Digestive Disease Week 2010. Turning Science into Medicine--part 2. PMID: 20582861 Ref: Pancreatic Cancer: a rare tumor with a devastating health toll. PMID: 21139967 |
Ref: Cost-effectiveness of modern radiotherapy techniques in locally advanced pancreatic cancer. PMID: 21773972 Ref: Hypoxia-inducible factor-1 up-regulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions. PMID: 22487528 Ref: MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. PMID: 22908323 Ref: Polysaccharide-K (PSK) increases p21(WAF/Cip1) and promotes apoptosis in pancreatic cancer cells. PMID: 23217280 |
Ref: Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-gamma and lipopolysaccharide in human pancreatic cancer cell lines. PMID: 23296709 Ref: M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway. PMID: 23752129 Ref: CD24+/CD38- as new prognostic marker for non-small cell lung cancer. PMID: 24094028 Ref: Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers. PMID: 24235843 |
Ref: Antitumor activity of gemcitabine can be potentiated in pancreatic cancer through modulation of TLR4/NF-kappaB signaling by 6-shogaol. PMID: 24424498 Ref: LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4. PMID: 24532253 Ref: Intervention on toll-like receptors in pancreatic cancer. PMID: 24914341 Ref: Pancreatic cancer derived exosomes regulate the expression of TLR4 in dendritic cells via miR-203. PMID: 25290620 Ref: Epigallocatechin gallate prevents inflammation by reducing macrophage infiltration and inhibiting tumor necrosis factor-alpha signaling in the pancreas of rats on a high-fat diet. PMID: 25453543 Ref: Gene expression disorders of innate antibacterial signaling pathway in pancreatic cancer patients: implications for leukocyte dysfunction and tumor progression. PMID: 26155170 |
Ref: Inflammation-induced ROS generation causes pancreatic cell death through modulation of Nrf2/NF-kappaB and SAPK/JNK pathway. PMID: 26189548 Ref: Pancreatic adenocarcinoma upregulated factor serves as adjuvant by activating dendritic cells through stimulation of TLR4. PMID: 26336989 Ref: Pancreatic cancer takes its Toll. PMID: 26573583 |
Ref: Soluble B7-H3 promotes the invasion and metastasis of pancreatic carcinoma cells through the TLR4/NF-kappaB pathway. PMID: 27273624 Ref: Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer. PMID: 27322081 Ref: CD14/TLR4 priming potentially recalibrates and exerts anti-tumor efficacy in tumor associated macrophages in a mouse model of pancreatic carcinoma. PMID: 27511884 Ref: Toll Like Receptor 2, 4, and 9 Signaling Promotes Autoregulative Tumor Cell Growth and VEGF/PDGF Expression in Human Pancreatic Cancer. PMID: 27941651 Ref: Dysregulation of signaling pathways associated with innate antibacterial immunity in patients with pancreatic cancer. PMID: 28450804 |
Ref: Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer. PMID: 28108630 Ref: High toll-like receptor (TLR) 9 expression is associated with better prognosis in surgically treated pancreatic cancer patients. PMID: 28191612 |
Ref: The role of cancer-associated fibroblast MRC-5 in pancreatic cancer. PMID: 29483967 Ref: Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer. PMID: 30111860 Ref: Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer. PMID: 30246618 Ref: Resistin effects on pancreatic cancer progression and chemoresistance are mediated through its receptors CAP1 and TLR4. PMID: 30317640 Ref: Toll-like receptors 2, 4 and 9 and hypoxia markers HIF-1alpha and CAIX in pancreatic intraepithelial neoplasia. PMID: 30357962 |