Primary Site >> Liver Cancer

Gene >> TLR3

Journal: J Biol Chem. 2005 Apr 29;280(17):16739-47.
Title: Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes.
Author: Li, Kui|Chen, Zihong|Kato, Nobuyuki|Gale, Michael Jr|Lemon, Stanley M
PMID: 15737993
Journal: J Cell Biochem. 2007 Apr 1;100(5):1301-12.
Title: TLR3 signaling in a hepatoma cell line is skewed towards apoptosis.
Author: Khvalevsky, Elina|Rivkin, Ludmila|Rachmilewitz, Jacob|Galun, Eithan|Giladi, Hilla
PMID: 17243100
Journal: Hepatology. 2008 Feb;47(2):385-95.
Title: Cell culture-produced hepatitis C virus impairs plasmacytoid dendritic cell function.
Author: Shiina, Masaaki|Rehermann, Barbara
PMID: 18064579
Journal: Int J Oncol. 2008 Nov;33(5):929-36.
Title: Dual topology of functional Toll-like receptor 3 expression in human hepatocellular carcinoma: differential signaling mechanisms of TLR3-induced NF-kappaB activation and apoptosis.
Author: Yoneda, Kentaro|Sugimoto, Kazushi|Shiraki, Katsuya|Tanaka, Junichiro|Beppu, Tetsuya|Fuke, Hiroyuki|Yamamoto, Norihiko|Masuya, Masahiro|Horie, Ryo|Uchida, Kazuhiko|Takei, Yoshiyuki
PMID: 18949355
Journal: Am J Pathol. 2010 Dec;177(6):3192-201.
Title: Small interfering RNAs induce target-independent inhibition of tumor growth and vasculature remodeling in a mouse model of hepatocellular carcinoma.
Author: Berge, Mathieu|Bonnin, Philippe|Sulpice, Eric|Vilar, Jose|Allanic, David|Silvestre, Jean-Sebastien|Levy, Bernard I|Tucker, Gordon C|Tobelem, Gerard|Merkulova-Rainon, Tatyana
PMID: 20971743
Journal: Cell Biol Int. 2011 Aug;35(8):803-10.
Title: Combination of Poly I:C and arsenic trioxide triggers apoptosis synergistically via activation of TLR3 and mitochondrial pathways in hepatocellular carcinoma cells.
Author: Shen, Peng|Jiang, Tingwang|Lu, Huiqi|Han, Huanxing|Luo, Rongcheng
PMID: 21418039
Journal: Hepatology. 2012 Mar;55(3):666-75.
Title: Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates.
Author: Li, Kui|Li, Nan L|Wei, Dahai|Pfeffer, Susan R|Fan, Meiyun|Pfeffer, Lawrence M
PMID: 22030901
Journal: Oncol Rep. 2012 Feb;27(2):396-402.
Title: Double-stranded RNA-induced TLR3 activation inhibits angiogenesis and triggers apoptosis of human hepatocellular carcinoma cells.
Author: Guo, Zhongying|Chen, Li|Zhu, Yuanyuan|Zhang, Yixin|He, Song|Qin, Jin|Tang, Xiaojun|Zhou, Jiaming|Wei, Yingze
PMID: 22075935
Journal: J Natl Cancer Inst. 2012 Dec 5;104(23):1796-807.
Title: Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients.
Author: Chew, Valerie|Tow, Charlene|Huang, Caleb|Bard-Chapeau, Emilie|Copeland, Neal G|Jenkins, Nancy A|Weber, Achim|Lim, Kiat Hon|Toh, Han Chong|Heikenwalder, Mathias|Ng, Irene Oi-Lin|Nardin, Alessandra|Abastado, Jean-Pierre
PMID: 23197495
Journal: J Natl Cancer Inst. 2012 Dec 5;104(23):1780-2.
Title: Guardian and selective killer: the versatile functions of TLR3 in hepatocellular carcinoma.
Author: Liu, Chen
PMID: 23197496
Journal: Tumour Biol. 2013 Jun;34(3):1589-94.
Title: Toll-like receptor 3 genetic variants and susceptibility to hepatocellular carcinoma and HBV-related hepatocellular carcinoma.
Author: Li, Guanggang|Zheng, Zhendong
PMID: 23404408
Journal: Oncol Rep. 2013 May;29(5):1737-43.
Title: The expression and function of Toll-like receptors 3 and 9 in human colon carcinoma.
Author: Nojiri, Keiichiro|Sugimoto, Kazushi|Shiraki, Katsuya|Tameda, Masahiko|Inagaki, Yuuji|Kusagawa, Satoko|Ogura, Suguru|Tanaka, Junichiro|Yoneda, Misao|Yamamoto, Norihiko|Okano, Hiroshi|Takei, Yoshiyuki|Ito, Masaaki|Kasai, Chika|Inoue, Hidekazu|Takase, Koujir
PMID: 23467704
Journal: J Hepatol. 2013 Oct;59(4):701-8.
Title: Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes.
Author: Brownell, Jessica|Wagoner, Jessica|Lovelace, Erica S|Thirstrup, Derek|Mohar, Isaac|Smith, Wesley|Giugliano, Silvia|Li, Kui|Crispe, I Nicholas|Rosen, Hugo R|Polyak, Stephen J
PMID: 23770038
Journal: Mol Med Rep. 2013 Oct;8(4):1037-42.
Title: Inhibitory effect of dsRNA TLR3 agonist in a rat hepatocellular carcinoma model.
Author: Xu, Yu-Yin|Chen, Li|Zhou, Jia-Ming|Wu, Yuan-Yuan|Zhu, Yuan-Yuan
PMID: 23970360
Journal: BMC Cancer. 2013 Nov 6;13:527.
Title: A synthetic dsRNA, as a TLR3 pathwaysynergist, combined with sorafenib suppresses HCC in vitro and in vivo.
Author: Xu, Yu-Yin|Chen, Li|Wang, Gui-Lan|Zhou, Jia-Ming|Zhang, Yi-Xin|Wei, Yin-Ze|Zhu, Yuan-Yuan|Qin, Jing
PMID: 24195809
Journal: Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11455-60.
Title: Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice.
Author: Hartwell, Hadley J|Petrosky, Keiko Y|Fox, James G|Horseman, Nelson D|Rogers, Arlin B
PMID: 25049387