Primary Site >> Liver Cancer
Gene >> TLR3
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Ref: Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. PMID: 15737993 |
Ref: TLR3 signaling in a hepatoma cell line is skewed towards apoptosis. PMID: 17243100 |
Ref: Cell culture-produced hepatitis C virus impairs plasmacytoid dendritic cell function. PMID: 18064579 Ref: Dual topology of functional Toll-like receptor 3 expression in human hepatocellular carcinoma: differential signaling mechanisms of TLR3-induced NF-kappaB activation and apoptosis. PMID: 18949355 |
Ref: Small interfering RNAs induce target-independent inhibition of tumor growth and vasculature remodeling in a mouse model of hepatocellular carcinoma. PMID: 20971743 |
Ref: Combination of Poly I:C and arsenic trioxide triggers apoptosis synergistically via activation of TLR3 and mitochondrial pathways in hepatocellular carcinoma cells. PMID: 21418039 |
Ref: Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates. PMID: 22030901 Ref: Double-stranded RNA-induced TLR3 activation inhibits angiogenesis and triggers apoptosis of human hepatocellular carcinoma cells. PMID: 22075935 Ref: Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients. PMID: 23197495 Ref: Guardian and selective killer: the versatile functions of TLR3 in hepatocellular carcinoma. PMID: 23197496 |
Ref: Toll-like receptor 3 genetic variants and susceptibility to hepatocellular carcinoma and HBV-related hepatocellular carcinoma. PMID: 23404408 Ref: The expression and function of Toll-like receptors 3 and 9 in human colon carcinoma. PMID: 23467704 Ref: Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes. PMID: 23770038 Ref: Inhibitory effect of dsRNA TLR3 agonist in a rat hepatocellular carcinoma model. PMID: 23970360 Ref: A synthetic dsRNA, as a TLR3 pathwaysynergist, combined with sorafenib suppresses HCC in vitro and in vivo. PMID: 24195809 |
Ref: Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. PMID: 25049387 |