Primary Site >> Colorectal Cancer

Gene >> TK1

Journal: Anticancer Res. 2000 Nov-Dec;20(6C):4815-20.
Title: A new cell proliferating marker: cytosolic thymidine kinase as compared to proliferating cell nuclear antigen in patients with colorectal carcinoma.
Author: Wu, J|Mao, Y|He, L|Wang, N|Wu, C|He, Q|Skog, S
PMID: 11205225
Journal: Int J Biol Markers. 2003 Jan-Mar;18(1):1-6.
Title: Mutation analysis in the coding sequence of thymidine kinase 1 in breast and colorectal cancer.
Author: Gilles, S I|Romain, S|Casellas, P|Ouafik, L'H|Fina, F|Combes, T|Vuaroquaux, V|Seitz, J F|Bonnier, P|Galiegue, S|Carayon, P|Martin, P M
PMID: 12699056
Journal: Clin Cancer Res. 2005 Apr 1;11(7):2612-9.
Title: Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer.
Author: Kidd, Elizabeth A|Yu, Jinsheng|Li, Xia|Shannon, William D|Watson, Mark A|McLeod, Howard L
PMID: 15814641
Journal: Int J Oncol. 2006 Feb;28(2):361-7.
Title: Potent anti-tumor and prolonged survival effects of E. coli-derived non-glycosylated kringle domain of tissue-type plasminogen activator.
Author: Kang, Byoung-Hak|Shim, Byoung-Shik|Lee, Soo Young|Lee, Suk-Keun|Hong, Yong-Kil|Joe, Young Ae
PMID: 16391790
Journal: Cancer Res. 2006 Aug 1;66(15):7621-9.
Title: In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.
Author: Leyton, Julius|Alao, John P|Da Costa, Marco|Stavropoulou, Alexandra V|Latigo, John R|Perumal, Meg|Pillai, Radhakrishna|He, Qimin|Atadja, Peter|Lam, Eric W-F|Workman, Paul|Vigushin, David M|Aboagye, Eric O
PMID: 16885362
Journal: Mol Cancer Ther. 2008 Sep;7(9):3112-21.
Title: Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901.
Author: Leyton, Julius|Smith, Graham|Lees, Mark|Perumal, Meg|Nguyen, Quang-de|Aigbirhio, Franklin I|Golovko, Oksana|He, Quimin|Workman, Paul|Aboagye, Eric O
PMID: 18790789
Journal: Mol Med Rep. 2009 Nov-Dec;2(6):923-9.
Title: Thymidine kinase 1 expression in atypical ductal hyperplasia significantly differs from usual ductal hyperplasia and ductal carcinoma in situ: A useful tool in tumor therapy management.
Author: Guan, Hong|Sun, Yanhua|Zan, Qin|Xu, Meiquan|Li, Yuan|Zhou, Ji|He, Ellen|Eriksson, Staffan|Wen, Wen|Skog, Sven
PMID: 21475922
Journal: Cancer Chemother Pharmacol. 2011 Aug;68(2):389-98.
Title: The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models.
Author: Na, Young-Soon|Jung, Kyung-Ah|Kim, Seung-Mi|Hong, Yong Sang|Ryu, Min-Hee|Jang, Se Jin|Moon, Dae Hyuk|Cho, Dong-Hyung|Kim, Jin Cheon|Lee, Jung Shin|Kim, Tae Won
PMID: 21046105
Journal: Anticancer Res. 2011 Jun;31(6):2135-9.
Title: Quantitative analysis of thymidine kinase 1 and 5'(3')-deoxyribonucleotidase mRNA expression: the role of fluorothymidine uptake.
Author: Lee, Seung Jin|Lee, Haeng Jung|Moon, Dae Hyuk
PMID: 21737633
Journal: Exp Ther Med. 2012 Feb;3(2):331-335.
Title: Elevated thymidine kinase 1 in serum following neoadjuvant chemotherapy predicts poor outcome for patients with locally advanced breast cancer.
Author: Huang, Zhi-Heng|Tian, Xing-Song|Li, Rong|Wang, Xian-Ming|Wen, Wen|Guan, Hong|Yang, Ya-Jie
PMID: 22969891
Journal: J Clin Lab Anal. 2013 May;27(3):220-6.
Title: Serum thymidine kinase 1 activity in solid tumor (breast and colorectal cancer) patients treated with adjuvant chemotherapy.
Author: Bolayirli, M|Papila, C|Korkmaz, G G|Papila, B|Aydogan, F|Karatas, A|Uzun, H
PMID: 23686779
Journal: PLoS One. 2013 Jun 10;8(6):e64961.
Title: Combined 5-FU and ChoKalpha inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts.
Author: de la Cueva, Ana|Ramirez de Molina, Ana|Alvarez-Ayerza, Nestor|Ramos, Ma Angeles|Cebrian, Arancha|Del Pulgar, Teresa Gomez|Lacal, Juan Carlos
PMID: 23762272
Journal: Pharmacol Res. 2013 Jun;72:61-8.
Title: Antitumor effect of 5-fluorouracil is enhanced by rosemary extract in both drug sensitive and resistant colon cancer cells.
Author: Gonzalez-Vallinas, Margarita|Molina, Susana|Vicente, Gonzalo|de la Cueva, Ana|Vargas, Teodoro|Santoyo, Susana|Garcia-Risco, Monica R|Fornari, Tiziana|Reglero, Guillermo|Ramirez de Molina, Ana
PMID: 23557932
Journal: Surg Endosc. 2014 Oct;28(10):2863-70.
Title: Effects of CO(2) pneumoperitoneum on the expression of thymidine kinase 1 and Ki67 in colorectal carcinoma cells.
Author: Yang, Chun-Kang|Guan, Shen|Ying, Min-Gang
PMID: 24853840
Journal: PLoS One. 2014 Jul 8;9(7):e101366.
Title: Phosphorylation status of thymidine kinase 1 following antiproliferative drug treatment mediates 3'-deoxy-3'-[18F]-fluorothymidine cellular retention.
Author: Sala, Roberta|Nguyen, Quang-De|Patel, Chirag B K|Mann, David|Steinke, Joachim H G|Vilar, Ramon|Aboagye, Eric O
PMID: 25003822
Journal: Eur Radiol. 2014 Dec;24(12):3199-209.
Title: Correlations of (18)F-fluorothymidine uptake with pathological tumour size, Ki-67 and thymidine kinase 1 expressions in primary and metastatic lymph node colorectal cancer foci.
Author: Nakajo, Masatoyo|Nakajo, Masayuki|Kajiya, Yoriko|Goto, Yuko|Jinguji, Megumi|Tanaka, Sadao|Fukukura, Yoshihiko|Tani, Atsushi|Higashi, Michiyo
PMID: 25120206
Journal: Cancer Chemother Pharmacol. 2015 May;75(5):1005-13.
Title: Positron emission tomography imaging of human colon cancer xenografts in mice with [18F]fluorothymidine after TAS-102 treatment.
Author: Lee, Haeng Jung|Oh, Seung Jun|Lee, Eun Jung|Chung, Jin Hwa|Kim, Yeseulmi|Ryu, Jin-Sook|Kim, Seog Young|Lee, Seung Jin|Moon, Dae Hyuk|Kim, Tae Won
PMID: 25776904
Journal: Int J Oncol. 2015;46(6):2327-34.
Title: Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA.
Author: Sakamoto, Kazuki|Yokogawa, Tatsushi|Ueno, Hiroyuki|Oguchi, Kei|Kazuno, Hiromi|Ishida, Keiji|Tanaka, Nozomu|Osada, Akiko|Yamada, Yukari|Okabe, Hiroyuki|Matsuo, Kenichi
PMID: 25901475
Journal: J Cancer. 2018 Jan 1;9(3):494-501.
Title: Clinical significance and diagnostic capacity of serum TK1, CEA, CA 19-9 and CA 72-4 levels in gastric and colorectal cancer patients.
Author: Ning, Shufang|Wei, Wene|Li, Jilin|Hou, Bingbing|Zhong, Jianhong|Xie, Yuxuan|Liu, Haizhou|Mo, Xianwei|Chen, Jiansi|Zhang, Litu
PMID: 29483954
Journal: Mol Cancer Res. 2018 Jun 4. pii: 1541-7786.MCR-17-0686.
Title: Thymidine Kinase 1 Loss Confers Trifluridine Resistance without Affecting 5-Fluorouracil Metabolism and Cytotoxicity.
Author: Edahiro, Keitaro|Iimori, Makoto|Kobunai, Takashi|Morikawa-Ichinose, Tomomi|Miura, Daisuke|Kataoka, Yuki|Niimi, Shinichiro|Wakasa, Takeshi|Saeki, Hiroshi|Oki, Eiji|Kitao, Hiroyuki|Maehara, Yoshihiko
PMID: 29866926
Journal: Cancer Cell Int. 2018 Sep 10;18:135.
Title: Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies.
Author: Weagel, Evita G|Burrup, Weston|Kovtun, Roman|Velazquez, Edwin J|Felsted, Abigail M|Townsend, Michelle H|Ence, Zachary E|Suh, Erica|Piccolo, Stephen R|Weber, K Scott|Robison, Richard A|O'Neill, Kim L
PMID: 30214377
Journal: Biotech Histochem. 2018 Oct 15:1-5.
Title: Thymidine kinase-1/CD31 double immunostaining for identifying activated tumor vessels.
Author: Okamura, S|Osaki, T|Nishimura, K|Ohsaki, H|Shintani, M|Matsuoka, H|Maeda, K|Shiogama, K|Itoh, T|Kamoshida, S
PMID: 30317880