Primary Site >> Colorectal Cancer
Gene >> TK1
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Ref: A new cell proliferating marker: cytosolic thymidine kinase as compared to proliferating cell nuclear antigen in patients with colorectal carcinoma. PMID: 11205225 |
Ref: Mutation analysis in the coding sequence of thymidine kinase 1 in breast and colorectal cancer. PMID: 12699056 |
Ref: Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer. PMID: 15814641 |
Ref: Potent anti-tumor and prolonged survival effects of E. coli-derived non-glycosylated kringle domain of tissue-type plasminogen activator. PMID: 16391790 Ref: In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography. PMID: 16885362 |
Ref: Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901. PMID: 18790789 |
Ref: Thymidine kinase 1 expression in atypical ductal hyperplasia significantly differs from usual ductal hyperplasia and ductal carcinoma in situ: A useful tool in tumor therapy management. PMID: 21475922 |
Ref: The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models. PMID: 21046105 Ref: Quantitative analysis of thymidine kinase 1 and 5'(3')-deoxyribonucleotidase mRNA expression: the role of fluorothymidine uptake. PMID: 21737633 |
Ref: Elevated thymidine kinase 1 in serum following neoadjuvant chemotherapy predicts poor outcome for patients with locally advanced breast cancer. PMID: 22969891 |
Ref: Antitumor effect of 5-fluorouracil is enhanced by rosemary extract in both drug sensitive and resistant colon cancer cells. PMID: 23557932 Ref: Serum thymidine kinase 1 activity in solid tumor (breast and colorectal cancer) patients treated with adjuvant chemotherapy. PMID: 23686779 Ref: Combined 5-FU and ChoKalpha inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts. PMID: 23762272 |
Ref: Effects of CO(2) pneumoperitoneum on the expression of thymidine kinase 1 and Ki67 in colorectal carcinoma cells. PMID: 24853840 Ref: Phosphorylation status of thymidine kinase 1 following antiproliferative drug treatment mediates 3'-deoxy-3'-[18F]-fluorothymidine cellular retention. PMID: 25003822 Ref: Correlations of (18)F-fluorothymidine uptake with pathological tumour size, Ki-67 and thymidine kinase 1 expressions in primary and metastatic lymph node colorectal cancer foci. PMID: 25120206 |
Ref: Positron emission tomography imaging of human colon cancer xenografts in mice with [18F]fluorothymidine after TAS-102 treatment. PMID: 25776904 Ref: Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA. PMID: 25901475 |
Ref: Clinical significance and diagnostic capacity of serum TK1, CEA, CA 19-9 and CA 72-4 levels in gastric and colorectal cancer patients. PMID: 29483954 Ref: Thymidine Kinase 1 Loss Confers Trifluridine Resistance without Affecting 5-Fluorouracil Metabolism and Cytotoxicity. PMID: 29866926 Ref: Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies. PMID: 30214377 Ref: Thymidine kinase-1/CD31 double immunostaining for identifying activated tumor vessels. PMID: 30317880 |