Primary Site >> Biliary tract Cancer

Gene >> TIMP2

Journal: World J Gastroenterol. 2002 Dec;8(6):1138-43.
Title: Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance.
Author: Fan, Yue-Zu|Zhang, Jing-Tao|Yang, Hu-Chuan|Yang, Yao-Qin
PMID: 12439941
Journal: Am J Gastroenterol. 2004 Jan;99(1):68-75.
Title: Expression of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in intraductal and nonintraductal growth type of cholangiocarcinoma.
Author: Jo Chae, Kwang|Rha, Sun Young|Oh, Bong-Kyeong|Koo, Ja Seung|Kim, Young Joo|Choi, Jinsub|Park, Chanil|Park, Young Nyun
PMID: 14687144
Journal: Zhonghua Zhong Liu Za Zhi. 2004 May;26(5):271-4.
Title: [The in vitro effect of norcantharidin on proliferation and invasion of human gallbladder carcinoma GBC-SD cells and its mechanism].
Author: Fan, Yue-zu|Fu, Jin-ye|Zhao, Ze-ming|Chen, Chun-qiu
PMID: 15312360
Journal: Hepatobiliary Pancreat Dis Int. 2004 Nov;3(4):599-602.
Title: The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study.
Author: Xiao, Mei|Zhou, Nin-Xing|Huang, Zhi-Qiang|Lu, Ya-Li|Chen, Ling-Hong|Wang, Dian-Jun|Chang, Wei-Lin
PMID: 15567754
Journal: J Hepatobiliary Pancreat Surg. 2004;11(6):409-16.
Title: Immunohistochemical study of characteristics of bile duct dysplasia evaluated on the basis of expression of metastasis/invasion-related factors and p53.
Author: Chiba, Hideo|Nagai, Hideo|Ohdaira, Takeshi|Yasuda, Yoshikazu|Saito, Ken
PMID: 15619017
Journal: J Exp Clin Cancer Res. 2004 Dec;23(4):599-606.
Title: A MEK inhibitor (U0126) markedly inhibits direct liver invasion of orthotopically inoculated human gallbladder cancer cells in nude mice.
Author: Horiuchi, H|Kawamata, H|Furihata, T|Omotehara, F|Hori, H|Shinagawa, Y|Ohkura, Y|Tachibana, M|Yamazaki, T|Ajiki, T|Kuroda, Y|Fujimori, T
PMID: 15743030
Journal: World J Gastroenterol. 2005 Apr 28;11(16):2431-7.
Title: Effect of norcantharidin on proliferation and invasion of human gallbladder carcinoma GBC-SD cells.
Author: Fan, Yue-Zu|Fu, Jin-Ye|Zhao, Ze-Ming|Chen, Cun-Qiu
PMID: 15832413
Journal: Zhonghua Yi Xue Za Zhi. 2006 Mar 14;86(10):693-9.
Title: [Effects of norcantharidin on angiogenesis of human gallbladder carcinoma and its anti-angiogenic mechanisms].
Author: Fan, Yue-zu|Chen, Chun-qiu|Zhao, Ze-ming|Sun, Wei
PMID: 16681930
Journal: Zhonghua Wai Ke Za Zhi. 2006 May 1;44(9):618-22.
Title: [Anti-tumor mechanism of norcantharidin for the implanted tumors of human gallbladder carcinoma in nude mice in vivo].
Author: Fan, Yue-zu|Zhao, Ze-ming|Fu, Jin-ye|Chen, Chun-qiu
PMID: 16784656
Journal: Int J Cancer. 2012 Aug 15;131(4):E416-24.
Title: Plasma hydroxyproline, MMP-7 and collagen I as novel predictive risk markers of hepatobiliary disease-associated cholangiocarcinoma.
Author: Prakobwong, Suksanti|Charoensuk, Lakhanawan|Hiraku, Yusuke|Pinlaor, Porntip|Pairojkul, Chawalit|Mairiang, Eimorn|Sithithaworn, Paiboon|Yongvanit, Puangrat|Khuntikeo, Narong|Pinlaor, Somchai
PMID: 21935919
Journal: Int J Oncol. 2012 May;40(5):1501-14.
Title: Norcantharidin: a potential antiangiogenic agent for gallbladder cancers in vitro and in vivo.
Author: Zhang, Jing-Tao|Fan, Yue-Zu|Chen, Chun-Qiu|Zhao, Zhe-Ming|Sun, Wei
PMID: 22200632
Journal: Int J Oncol. 2013 Jun;42(6):2103-15.
Title: Contribution of the PI3K/MMPs/Ln-5gamma2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.
Author: Lu, Xin-Sui|Sun, Wei|Ge, Chun-Yan|Zhang, Wen-Zhong|Fan, Yue-Zu
PMID: 23588386
Journal: BMC Cancer. 2014 Mar 15;14:193.
Title: Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5gamma2 signaling pathway.
Author: Zhang, Jing-Tao|Sun, Wei|Zhang, Wen-Zhong|Ge, Chun-Yan|Liu, Zhong-Yan|Zhao, Ze-Ming|Lu, Xing-Sui|Fan, Yue-Zu
PMID: 24628713
Journal: Int J Oncol. 2015 Feb;46(2):627-40.
Title: Norcantharidin enhances TIMP2 antivasculogenic mimicry activity for human gallbladder cancers through downregulating MMP2 and MT1MMP.
Author: Zhu, Wei|Sun, Wei|Zhang, Jing-Tao|Liu, Zhong-Yan|Li, Xin-Ping|Fan, Yue-Zu
PMID: 25405519