Primary Site >> Pancreatic Cancer
Gene >> TGFBR2
| 1. | |||||||||||
| Journal: | Cancer Res. 1993 Jun 15;53(12):2704-7. | ||||||||||
| Title: | Enhanced expression of the type II transforming growth factor beta receptor in human pancreatic cancer cells without alteration of type III receptor expression. | ||||||||||
| Author: | Friess, H|Yamanaka, Y|Buchler, M|Berger, H G|Kobrin, M S|Baldwin, R L|Korc, M | ||||||||||
| PMID: | 8389240 | ||||||||||
| 2. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 1996 Oct;17(2):88-93. | ||||||||||
| Title: | Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: identification of a I-cM region of common allelic loss. | ||||||||||
| Author: | Kimura, M|Abe, T|Sunamura, M|Matsuno, S|Horii, A | ||||||||||
| PMID: | 8913725 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 1997 Sep 15;57(18):3929-34. | ||||||||||
| Title: | Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. | ||||||||||
| Author: | Grau, A M|Zhang, L|Wang, W|Ruan, S|Evans, D B|Abbruzzese, J L|Zhang, W|Chiao, P J | ||||||||||
| PMID: | 9307274 | ||||||||||
| 4. | |||||||||||
| Journal: | Dig Dis Sci. 1997 Oct;42(10):2054-63. | ||||||||||
| Title: | Presence of two signaling TGF-beta receptors in human pancreatic cancer correlates with advanced tumor stage. | ||||||||||
| Author: | Lu, Z|Friess, H|Graber, H U|Guo, X|Schilling, M|Zimmermann, A|Korc, M|Buchler, M W | ||||||||||
| PMID: | 9365135 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 1998 Mar 27;273(13):7495-500. | ||||||||||
| Title: | Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells. | ||||||||||
| Author: | Kleeff, J|Korc, M | ||||||||||
| PMID: | 9516449 | ||||||||||
| 6. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 1998 Jun;22(2):138-44. | ||||||||||
| Title: | Novel mutations in the polyadenine tract of the transforming growth factor beta type II receptor gene are found in a subpopulation of human pancreatic adenocarcinomas. | ||||||||||
| Author: | Venkatasubbarao, K|Ahmed, M M|Swiderski, C|Harp, C|Lee, E Y|McGrath, P|Mohiuddin, M|Strodel, W|Freeman, J W | ||||||||||
| PMID: | 9598801 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Cancer. 1998 Oct 5;78(2):255-60. | ||||||||||
| Title: | Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer. | ||||||||||
| Author: | Wagner, M|Kleeff, J|Lopez, M E|Bockman, I|Massaque, J|Korc, M | ||||||||||
| PMID: | 9754660 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Res. 1998 Dec 1;58(23):5329-32. | ||||||||||
| Title: | Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas. | ||||||||||
| Author: | Goggins, M|Shekher, M|Turnacioglu, K|Yeo, C J|Hruban, R H|Kern, S E | ||||||||||
| PMID: | 9850059 | ||||||||||
| 9. | |||||||||||
| Journal: | Pancreas. 1999 Nov;19(4):370-6. | ||||||||||
| Title: | Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer. | ||||||||||
| Author: | Wagner, M|Kleeff, J|Friess, H|Buchler, M W|Korc, M | ||||||||||
| PMID: | 10547197 | ||||||||||
| 10. | |||||||||||
| Journal: | Dig Dis Sci. 1999 Sep;44(9):1793-802. | ||||||||||
| Title: | Overexpression of Smad2 and colocalization with TGF-beta1 in human pancreatic cancer. | ||||||||||
| Author: | Kleeff, J|Friess, H|Simon, P|Susmallian, S|Buchler, P|Zimmermann, A|Buchler, M W|Korc, M | ||||||||||
| PMID: | 10505717 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncogene. 1999 Sep 23;18(39):5363-72. | ||||||||||
| Title: | The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. | ||||||||||
| Author: | Kleeff, J|Ishiwata, T|Maruyama, H|Friess, H|Truong, P|Buchler, M W|Falb, D|Korc, M | ||||||||||
| PMID: | 10498890 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncogene. 2000 Nov 16;19(48):5525-33. | ||||||||||
| Title: | Inhibition of farnesyltransferase increases TGFbeta type II receptor expression and enhances the responsiveness of human cancer cells to TGFbeta. | ||||||||||
| Author: | Adnane, J|Bizouarn, F A|Chen, Z|Ohkanda, J|Hamilton, A D|Munoz-Antonia, T|Sebti, S M | ||||||||||
| PMID: | 11114730 | ||||||||||
| 13. | |||||||||||
| Journal: | Curr Opin Gastroenterol. 2000 Sep;16(5):419-25. | ||||||||||
| Title: | Molecular genetics of ductal pancreatic neoplasia. | ||||||||||
| Author: | Su, G H|Kern, S E | ||||||||||
| PMID: | 17031113 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Res. 2001 Apr 1;61(7):3139-44. | ||||||||||
| Title: | Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability. | ||||||||||
| Author: | Yamamoto, H|Itoh, F|Nakamura, H|Fukushima, H|Sasaki, S|Perucho, M|Imai, K | ||||||||||
| PMID: | 11306499 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Oncol. 2001 Jul;19(1):71-81. | ||||||||||
| Title: | Altered expression of TGFB receptors and mitogenic effects of TGFB in pancreatic carcinomas. | ||||||||||
| Author: | Jonson, T|Albrechtsson, E|Axelson, J|Heidenblad, M|Gorunova, L|Johansson, B|Hoglund, M | ||||||||||
| PMID: | 11408925 | ||||||||||
| 16. | |||||||||||
| Journal: | Clin Cancer Res. 2001 Sep;7(9):2931-40. | ||||||||||
| Title: | Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation. | ||||||||||
| Author: | Rowland-Goldsmith, M A|Maruyama, H|Kusama, T|Ralli, S|Korc, M | ||||||||||
| PMID: | 11555612 | ||||||||||
| 17. | |||||||||||
| Journal: | Zhonghua Bing Li Xue Za Zhi. 2001 Dec;30(6):439-42. | ||||||||||
| Title: | [Detection of the expression of Smad4, transforming growth factor beta(1) and beta receptor II proteins in paraffin-embedded human pancreatic cancer tissues]. | ||||||||||
| Author: | Gu, L|Chen, J|Liu, T|Li, L|Lu, Z|Luo, Y | ||||||||||
| PMID: | 11866987 | ||||||||||
| 18. | |||||||||||
| Journal: | Cell Tissue Res. 2002 May;308(2):205-14. Epub 2002 Apr 11. | ||||||||||
| Title: | Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene. | ||||||||||
| Author: | Ku, Ja-Lok|Yoon, Kyong-Ah|Kim, Woo-Ho|Jang, Young|Suh, Kyung-Suk|Kim, Sun-Whe|Park, Yong-Hyun|Park, Jae-Gahb | ||||||||||
| PMID: | 12037578 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2002 Nov 7;21(51):7883-90. | ||||||||||
| Title: | Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2. | ||||||||||
| Author: | Alcock, Rachael A|Dey, Swatee|Chendil, Damodaran|Inayat, Mohammed S|Mohiuddin, Mohammed|Hartman, George|Chatfield, Lee K|Gallicchio, Vincent S|Ahmed, Mansoor M | ||||||||||
| PMID: | 12420225 | ||||||||||
| 20. | |||||||||||
| Journal: | J Cell Physiol. 2003 Jan;194(1):88-99. | ||||||||||
| Title: | Rap1 reverses transcriptional repression of TGF-beta type II receptor by a mechanism involving AP-1 in the human pancreatic cancer cell line, UK Pan-1. | ||||||||||
| Author: | Fralix, Kimberly D|Zhao, Shujie|Venkatasubbarao, Kolaparthi|Freeman, James W | ||||||||||
| PMID: | 12447993 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2003 May 15;63(10):2624-30. | ||||||||||
| Title: | Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells. | ||||||||||
| Author: | Zhao, Shujie|Venkatasubbarao, Kolaparthi|Li, Senlin|Freeman, James W | ||||||||||
| PMID: | 12750289 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Res. 2003 Mar 1;63(5):994-9. | ||||||||||
| Title: | Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. | ||||||||||
| Author: | Hempen, Paula M|Zhang, Lin|Bansal, Ravi K|Iacobuzio-Donahue, Christine A|Murphy, Kathleen M|Maitra, Anirban|Vogelstein, Bert|Whitehead, Robert H|Markowitz, Sanford D|Willson, James K V|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E | ||||||||||
| PMID: | 12615714 | ||||||||||
| 23. | |||||||||||
| Journal: | J Biol Chem. 2005 Mar 18;280(11):10047-54. Epub 2005 Jan 12. | ||||||||||
| Title: | Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex. | ||||||||||
| Author: | Huang, Weiqi|Zhao, Shujie|Ammanamanchi, Sudhakar|Brattain, Michael|Venkatasubbarao, Kolaparthi|Freeman, James W | ||||||||||
| PMID: | 15647279 | ||||||||||
| 24. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2257-61. Epub 2006 Feb 3. | ||||||||||
| Title: | A microRNA expression signature of human solid tumors defines cancer gene targets. | ||||||||||
| Author: | Volinia, Stefano|Calin, George A|Liu, Chang-Gong|Ambs, Stefan|Cimmino, Amelia|Petrocca, Fabio|Visone, Rosa|Iorio, Marilena|Roldo, Claudia|Ferracin, Manuela|Prueitt, Robyn L|Yanaihara, Nozumu|Lanza, Giovanni|Scarpa, Aldo|Vecchione, Andrea|Negrini, Massimo| | ||||||||||
| PMID: | 16461460 | ||||||||||
| 25. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2010 Aug 5;29:104. | ||||||||||
| Title: | PKCalpha-induced drug resistance in pancreatic cancer cells is associated with transforming growth factor-beta1. | ||||||||||
| Author: | Chen, Ying|Yu, Guanzhen|Yu, Danghui|Zhu, Minghua | ||||||||||
| PMID: | 20684793 | ||||||||||
| 26. | |||||||||||
| Journal: | Genome Res. 2012 Feb;22(2):208-19. | ||||||||||
| Title: | Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. | ||||||||||
| Author: | Wang, Linghua|Tsutsumi, Shuichi|Kawaguchi, Tokuichi|Nagasaki, Koichi|Tatsuno, Kenji|Yamamoto, Shogo|Sang, Fei|Sonoda, Kohtaro|Sugawara, Minoru|Saiura, Akio|Hirono, Seiko|Yamaue, Hiroki|Miki, Yoshio|Isomura, Minoru|Totoki, Yasushi|Nagae, Genta|Isagawa, Tak | ||||||||||
| PMID: | 22156295 | ||||||||||
| 27. | |||||||||||
| Journal: | Carcinogenesis. 2012 Jul;33(7):1384-90. | ||||||||||
| Title: | Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer. | ||||||||||
| Author: | Li, Donghui|Duell, Eric J|Yu, Kai|Risch, Harvey A|Olson, Sara H|Kooperberg, Charles|Wolpin, Brian M|Jiao, Li|Dong, Xiaoqun|Wheeler, Bill|Arslan, Alan A|Bueno-de-Mesquita, H Bas|Fuchs, Charles S|Gallinger, Steven|Gross, Myron|Hartge, Patricia|Hoover, Rober | ||||||||||
| PMID: | 22523087 | ||||||||||
| 28. | |||||||||||
| Journal: | PLoS One. 2012;7(6):e39684. | ||||||||||
| Title: | Concomitant targeting of EGF receptor, TGF-beta and SRC points to a novel therapeutic approach in pancreatic cancer. | ||||||||||
| Author: | Deharvengt, Sophie|Marmarelis, Melina|Korc, Murray | ||||||||||
| PMID: | 22761868 | ||||||||||
| 29. | |||||||||||
| Journal: | Nature. 2012 Nov 15;491(7424):399-405. | ||||||||||
| Title: | Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. | ||||||||||
| Author: | Biankin, Andrew V|Waddell, Nicola|Kassahn, Karin S|Gingras, Marie-Claude|Muthuswamy, Lakshmi B|Johns, Amber L|Miller, David K|Wilson, Peter J|Patch, Ann-Marie|Wu, Jianmin|Chang, David K|Cowley, Mark J|Gardiner, Brooke B|Song, Sarah|Harliwong, Ivon|Idrisog | ||||||||||
| PMID: | 23103869 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Res. 2013 Apr 1;73(7):2221-34. | ||||||||||
| Title: | Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. | ||||||||||
| Author: | Miyabayashi, Koji|Ijichi, Hideaki|Mohri, Dai|Tada, Motohisa|Yamamoto, Keisuke|Asaoka, Yoshinari|Ikenoue, Tsuneo|Tateishi, Keisuke|Nakai, Yousuke|Isayama, Hiroyuki|Morishita, Yasuyuki|Omata, Masao|Moses, Harold L|Koike, Kazuhiko | ||||||||||
| PMID: | 23378339 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Sci. 2013 Mar;104(3):337-44. | ||||||||||
| Title: | Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer. | ||||||||||
| Author: | Takahashi, Ryota|Hirata, Yoshihiro|Sakitani, Kosuke|Nakata, Wachiko|Kinoshita, Hiroto|Hayakawa, Yoku|Nakagawa, Hayato|Sakamoto, Kei|Hikiba, Yohko|Ijichi, Hideaki|Moses, Harold L|Maeda, Shin|Koike, Kazuhiko | ||||||||||
| PMID: | 23237571 | ||||||||||
| 32. | |||||||||||
| Journal: | Int J Biol Markers. 2015 May 26;30(2):e226-33. | ||||||||||
| Title: | Identification of biomarkers for the prognosis of pancreatic ductal adenocarcinoma with miRNA microarray data. | ||||||||||
| Author: | Wang, Song|Zhao, Yanxun|Li, Dongsheng|Zhu, Liangchen|Shen, Zugang | ||||||||||
| PMID: | 25791160 | ||||||||||
| 33. | |||||||||||
| Journal: | Gastroenterology. 2015 Dec;149(7):1932-1943.e9. | ||||||||||
| Title: | Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer. | ||||||||||
| Author: | Nagathihalli, Nagaraj S|Castellanos, Jason A|Shi, Chanjuan|Beesetty, Yugandhar|Reyzer, Michelle L|Caprioli, Richard|Chen, Xi|Walsh, Alex J|Skala, Melissa C|Moses, Harold L|Merchant, Nipun B | ||||||||||
| PMID: | 26255562 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncogene. 2016 May 12;35(19):2485-95. | ||||||||||
| Title: | Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer. | ||||||||||
| Author: | Zhang, S|Chung, W-C|Xu, K | ||||||||||
| PMID: | 26279302 | ||||||||||
| 35. | |||||||||||
| Journal: | Clin Cancer Res. 2017 Mar 15;23(6):1607-1620. | ||||||||||
| Title: | Mutant p53 Together with TGFbeta Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer. | ||||||||||
| Author: | Zhong, Yi|Macgregor-Das, Anne|Saunders, Tyler|Whittle, Martin C|Makohon-Moore, Alvin|Kohutek, Zachary A|Poling, Justin|Herbst, Brian T|Javier, Breanna M|Cope, Leslie|Leach, Steven D|Hingorani, Sunil R|Iacobuzio-Donahue, Christine A | ||||||||||
| PMID: | 27637888 | ||||||||||
| 36. | |||||||||||
| Journal: | Mol Cancer Res. 2017 Aug;15(8):1029-1039. | ||||||||||
| Title: | miR-202 Diminishes TGFbeta Receptors and Attenuates TGFbeta1-Induced EMT in Pancreatic Cancer. | ||||||||||
| Author: | Mody, Hardik R|Hung, Sau Wai|Pathak, Rakesh K|Griffin, Jazmine|Cruz-Monserrate, Zobeida|Govindarajan, Rajgopal | ||||||||||
| PMID: | 28373289 | ||||||||||
| 37. | |||||||||||
| Journal: | J Assoc Genet Technol. 2017;43(3):113-127. | ||||||||||
| Title: | Elucidation of Novel Chromosomal Abnormalities in Pancreatic Cancer: Conventional and Molecular Cytogenetic Characterization of 16 Pancreatic Cell Lines. | ||||||||||
| Author: | Shabsovich, David|Tirado, Carlos A | ||||||||||
| PMID: | 28809762 | ||||||||||
| 38. | |||||||||||
| Journal: | Int J Oncol. 2018 Mar;52(3):892-900. | ||||||||||
| Title: | Endoglin (CD105) and SMAD4 regulate spheroid formation and the suppression of the invasive ability of human pancreatic cancer cells. | ||||||||||
| Author: | Kokaji, Eri|Shimomura, Akiko|Minamisaka, Takashi|Nakajima, Takahiko|Miwa, Shigeharu|Hatta, Hideki|Nishida, Takeshi|Kiya, Chieko|Imura, Johji | ||||||||||
| PMID: | 29393426 | ||||||||||
| 39. | |||||||||||
| Journal: | Cell Death Dis. 2018 Jun 13;9(6):706. | ||||||||||
| Title: | Linc00462 promotes pancreatic cancer invasiveness through the miR-665/TGFBR1-TGFBR2/SMAD2/3 pathway. | ||||||||||
| Author: | Zhou, Bin|Guo, Weidong|Sun, Chuandong|Zhang, Bingyuan|Zheng, Fang | ||||||||||
| PMID: | 29899418 | ||||||||||