Primary Site >> Stomach Cancer

Gene >> TFF1

Journal: FEBS Lett. 1990 Feb 26;261(2):283-6.
Title: Expression of the pS2 gene in human gastric cancer cells derived from poorly differentiated adenocarcinoma.
Author: Takahashi, H|Kida, N|Fujii, R|Tanaka, K|Ohta, M|Mori, K|Hayashi, K
PMID: 2311759
Journal: J Pathol. 1993 Dec;171(4):263-9.
Title: pS2 protein in gastric carcinoma and normal gastric mucosa: association with clincopathological parameters and patient survival.
Author: Muller, W|Borchard, F
PMID: 8158455
Journal: Int J Cancer. 1994 Jan 2;56(1):52-5.
Title: Expression pattern of breast-cancer-associated protein pS2/BCEI in colorectal tumors.
Author: Welter, C|Theisinger, B|Rio, M C|Seitz, G|Schuder, G|Blin, N
PMID: 7505265
Journal: Eur J Cancer. 1996 Aug;32A(9):1585-90.
Title: pS2 protein expression in gastric carcinoma. An immunohistochemical and immunoradiometric study.
Author: Machado, J C|Carneiro, F|Ribeiro, P|Blin, N|Sobrinho-Simoes, M
PMID: 8911122
Journal: Nihon Shokakibyo Gakkai Zasshi. 1996 Oct;93(10):707-16.
Title: [Expression of trefoil group antigen pS2 in human gastric cancer].
Author: Oguri, T|Onda, M|Tokunaga, A|Asano, G
PMID: 8921704
Journal: Eur J Hum Genet. 1996;4(6):308-15.
Title: Human trefoil peptides: genomic structure in 21q22.3 and coordinated expression.
Author: Gott, P|Beck, S|Machado, J C|Carneiro, F|Schmitt, H|Blin, N
PMID: 9043862
Journal: FEBS Lett. 1997 May 19;408(2):121-3.
Title: Rolling in the clover: trefoil factor family (TFF)-domain peptides, cell migration and cancer.
Author: Wright, N A|Hoffmann, W|Otto, W R|Rio, M C|Thim, L
PMID: 9187350
Journal: Jpn J Cancer Res. 1998 Mar;89(3):278-82.
Title: Loss of pS2 protein expression is an early event of intestinal-type gastric cancer.
Author: Wu, M S|Shun, C T|Wang, H P|Lee, W J|Wang, T H|Lin, J T
PMID: 9600121
Journal: FEBS Lett. 1998 Nov 13;439(1-2):180-4.
Title: Osmotic changes and ethanol modify TFF gene expression in gastrointestinal cell lines.
Author: Ludeking, A|Fegert, P|Blin, N|Gott, P
PMID: 9849902
Journal: J Pathol. 1999 Jul;188(3):312-7.
Title: The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS.
Author: Calnan, D P|Westley, B R|May, F E|Floyd, D N|Marchbank, T|Playford, R J
PMID: 10419601
Journal: J Pathol. 2000 Mar;190(4):437-43.
Title: Gastric carcinoma exhibits distinct types of cell differentiation: an immunohistochemical study of trefoil peptides (TFF1 and TFF2) and mucins (MUC1, MUC2, MUC5AC, and MUC6).
Author: Machado, J C|Nogueira, A M|Carneiro, F|Reis, C A|Sobrinho-Simoes, M
PMID: 10699992
Journal: Cancer Lett. 2000 Feb 28;149(1-2):125-34.
Title: DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis.
Author: Fujimoto, J|Yasui, W|Tahara, H|Tahara, E|Kudo, Y|Yokozaki, H|Tahara, E
PMID: 10737716
Journal: J Gastroenterol. 2000;35 Suppl 12:111-5.
Title: Genetic and epigenetic alterations in multistep carcinogenesis of the stomach.
Author: Yasui, W|Yokozaki, H|Fujimoto, J|Naka, K|Kuniyasu, H|Tahara, E
PMID: 10779229
Journal: Cancer Lett. 2000 Oct 16;159(1):15-21.
Title: Mapping of a new target region of allelic loss at 21q22 in primary gastric cancers.
Author: Park, W S|Oh, R R|Park, J Y|Yoo, N J|Lee, S H|Shin, M S|Kim, S Y|Kim, Y S|Lee, J H|Kim, H S|An, W G|Lee, J Y
PMID: 10974401
Journal: Gastroenterology. 2000 Sep;119(3):691-8.
Title: Somatic mutations of the trefoil factor family 1 gene in gastric cancer.
Author: Park, W S|Oh, R R|Park, J Y|Lee, J H|Shin, M S|Kim, H S|Lee, H K|Kim, Y S|Kim, S Y|Lee, S H|Yoo, N J|Lee, J Y
PMID: 10982763
Journal: FEBS Lett. 2001 Jan 19;488(3):206-10.
Title: Aspirin promotes TFF2 gene activation in human gastric cancer cell lines.
Author: Azarschab, P|Al-Azzeh, E|Kornberger, W|Gott, P
PMID: 11163773
Journal: Int J Biol Markers. 2001 Jan-Mar;16(1):37-44.
Title: Prognostic significance of cytosolic pS2 protein content in gastric cancer.
Author: Suarez, C|Vizoso, F|Rodriguez, J C|Garcia, I|Raigoso, P|Allende, M T|Garcia-Muniz, J L|Garcia-Moran, M
PMID: 11288953
Journal: Lab Invest. 2001 Mar;81(3):397-408.
Title: Augmented intestinal trefoil factor (TFF3) and loss of pS2 (TFF1) expression precedes metaplastic differentiation of gastric epithelium.
Author: Taupin, D|Pedersen, J|Familari, M|Cook, G|Yeomans, N|Giraud, A S
PMID: 11310832
Journal: Int J Oncol. 2001 Nov;19(5):997-1001.
Title: Expression of WNT10A in human cancer.
Author: Kirikoshi, H|Inoue, S|Sekihara, H|Katoh, M
PMID: 11605000
Journal: J Cell Biol. 2002 May 27;157(5):761-70. Epub 2002 May 28.
Title: The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis.
Author: Bossenmeyer-Pourie, Carine|Kannan, Rama|Ribieras, Stephane|Wendling, Corinne|Stoll, Isabelle|Thim, Lars|Tomasetto, Catherine|Rio, Marie-Christine
PMID: 12034770
Journal: Int J Oncol. 2002 Sep;21(3):655-9.
Title: Expression of TFF1, TFF2 and TFF3 in gastric cancer.
Author: Kirikoshi, Hiroyuki|Katoh, Masaru
PMID: 12168114
Journal: J Pathol. 2002 Aug;197(5):582-8.
Title: Expression of trefoil peptides (TFF1, TFF2, and TFF3) in gastric carcinomas, intestinal metaplasia, and non-neoplastic gastric tissues.
Author: Leung, Wai K|Yu, Jun|Chan, Francis K L|To, Ka F|Chan, Michael W Y|Ebert, M P A|Ng, Enders K W|Chung, S C Sydney|Malfertheiner, Peter|Sung, Joseph J Y
PMID: 12210076
Journal: Mol Med. 2002 May;8(5):273-82.
Title: Trefoil factor 1 (TFF1/pS2) deficiency activates the unfolded protein response.
Author: Torres, Luis-Fernando|Karam, Sherif M|Wendling, Corinne|Chenard, Marie-Pierre|Kershenobich, David|Tomasetto, Catherine|Rio, Marie-Christine
PMID: 12359958
Journal: Lab Invest. 2002 Oct;82(10):1319-26.
Title: Loss of heterozygosity and promoter methylation, but not mutation, may underlie loss of TFF1 in gastric carcinoma.
Author: Carvalho, Ralph|Kayademir, Tuncay|Soares, Paula|Canedo, Paulo|Sousa, Sonia|Oliveira, Carla|Leistenschneider, Peter|Seruca, Raquel|Gott, Peter|Blin, Nikolaus|Carneiro, Fatima|Machado, Jose Carlos
PMID: 12379766
Journal: Mol Cancer Ther. 2002 Apr;1(6):405-15.
Title: Coordinate late expression of trefoil peptide genes (pS2/TFF1 and ITF/TFF3) in human breast, colon, and gastric tumor cells exposed to X-rays.
Author: Balcer-Kubiczek, Elizabeth K|Harrison, George H|Xu, Jing-Fan|Gutierrez, Peter L
PMID: 12477053
Journal: Magn Reson Med. 2003 Jun;49(6):1033-6.
Title: Magnetic resonance imaging of gastric cancer in Tff1 knock-out mice.
Author: Berr, Stuart S|Roche, James K|El-Rifai, Wa'el|Smith, Michael F Jr|Powell, Steven M
PMID: 12768581
Journal: Int J Mol Med. 2003 Jul;12(1):3-9.
Title: Trefoil factors and human gastric cancer (review).
Author: Katoh, Masaru
PMID: 12792801
Journal: Gastroenterology. 2003 Aug;125(2):510-21.
Title: Transcriptional regulation of the human trefoil factor, TFF1, by gastrin.
Author: Khan, Zara E|Wang, Timothy C|Cui, Guanglin|Chi, Alfred L|Dimaline, Rod
PMID: 12891554
Journal: Lab Invest. 2003 Oct;83(10):1403-13.
Title: Aberrant expression of trefoil factor family 1 in biliary epithelium in hepatolithiasis and cholangiocarcinoma.
Author: Sasaki, Motoko|Tsuneyama, Koichi|Nakanuma, Yasuni
PMID: 14563942
Journal: Cancer. 2003 Nov 15;98(10):2184-91.
Title: Decreased abundance of trefoil factor 1 transcript in the majority of gastric carcinomas.
Author: Beckler, Andrew D|Roche, James K|Harper, Jeffrey C|Petroni, Gina|Frierson, Henry F Jr|Moskaluk, Christopher A|El-Rifai, Wa'el|Powell, Steven M
PMID: 14601088
Journal: Gastroenterology. 2004 Jan;126(1):196-207.
Title: Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.
Author: Judd, Louise M|Alderman, Barbara M|Howlett, Meegan|Shulkes, Arthur|Dow, Chris|Moverley, Jill|Grail, Diane|Jenkins, Brendan J|Ernst, Matthias|Giraud, Andrew S
PMID: 14699500
Journal: Biochem Biophys Res Commun. 2004 Jan 23;313(4):931-7.
Title: Highly specific marker genes for detecting minimal gastric cancer cells in cytology negative peritoneal washings.
Author: Mori, Kazuhiko|Aoyagi, Kazuhiko|Ueda, Tetsuya|Danjoh, Inaho|Tsubosa, Yasuhiro|Yanagihara, Kazuyoshi|Matsuno, Yoshihiro|Sasako, Mitsuru|Sakamoto, Hiromi|Mafune, Ken ichi|Kaminishi, Michio|Yoshida, Teruhiko|Terada, Masaaki|Sasaki, Hiroki
PMID: 14706632
Journal: Zhonghua Nei Ke Za Zhi. 2004 Mar;43(3):195-7.
Title: [The expression of trefoil factor 1 and trefoil factor 2 in gastric cancer and precancer].
Author: Shi, Shu-qing|Cai, Jian-ting
PMID: 15059374
Journal: Virchows Arch. 2004 Jun;444(6):536-41. Epub 2004 Apr 8.
Title: Differentiation pathways in duodenal and ampullary carcinomas: a comparative study on mucin and trefoil peptide expression, including gastric and colon carcinomas.
Author: Gurbuz, Yesim|Kloppel, Gunter
PMID: 15071739
Journal: Eur J Gastroenterol Hepatol. 2004 Jan;16(1):63-7.
Title: Promoter selection for the cytosine deaminase suicide gene constructs in gastric cancer.
Author: Aberle, Susanne|Schug, Nicola|Mathlouthi, Rabea|Seitz, Gerhard|Kupper, Jan-Heiner|Schroder, Kristina|Blin, Nikolaus
PMID: 15095854
Journal: Aliment Pharmacol Ther. 2004 Jul;20 Suppl 1:17-24.
Title: Sex differences in mucosal response to Helicobacter pylori infection in the stomach and variations in interleukin-8, COX-2 and trefoil factor family 1 gene expression.
Author: Kato, S|Matsukura, N|Togashi, A|Masuda, G|Matsuda, N|Yamada, N|Naito, Z|Matsuhisa, T|Tajiri, T
PMID: 15298601
Journal: Aliment Pharmacol Ther. 2004 Jul;20 Suppl 1:171-6.
Title: Indometacin up-regulates TFF2 expression in gastric epithelial cells.
Author: Koitabashi, A|Shimada, T|Fujii, Y|Hashimoto, T|Hosaka, K|Tabei, K|Namatame, T|Yoneda, M|Hiraishi, H|Terano, A
PMID: 15298624
Journal: Carcinogenesis. 2005 Jun;26(6):1129-37. Epub 2005 Mar 10.
Title: Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer.
Author: Kang, Weiqun|Nielsen, Ole|Fenger, Claus|Leslie, Graham|Holmskov, Uffe|Reid, Kenneth B M
PMID: 15760920
Journal: World J Gastroenterol. 2005 May 7;11(17):2674-7.
Title: Relationship between trefoil factor 1 expression and gastric mucosa injuries and gastric cancer.
Author: Ren, Jian-Lin|Luo, Jin-Yan|Lu, Ya-Pi|Wang, Lin|Shi, Hua-Xiu
PMID: 15849833
Journal: Biochemistry. 2005 Jun 7;44(22):7967-75.
Title: Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C.
Author: Westley, Bruce R|Griffin, S Michael|May, Felicity E B
PMID: 15924415
Journal: J Gastroenterol Hepatol. 2005 Aug;20(8):1266-78.
Title: Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors.
Author: Judd, Louise M|Andringa, Anastasia|Rubio, Carlos A|Spicer, Zachary|Shull, Gary E|Miller, Marian L
PMID: 16048577
Journal: Am J Pathol. 2005 Aug;167(2):577-84.
Title: Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis.
Author: Johnson, Adam H|Frierson, Henry F|Zaika, Alexander|Powell, Steven M|Roche, James|Crowe, Sheila|Moskaluk, Christopher A|El-Rifai, Wa'el
PMID: 16049341
Journal: Di Yi Jun Yi Da Xue Xue Bao. 2005 Sep;25(9):1178-80.
Title: [Association of trefoil factor 1 expression with gastric mucosa injuries and gastric cancer].
Author: Ren, Jian-lin|Luo, Jin-yan|Lu, Ya-pi|Wang, Lin|Chen, Jian-min|Shi, Hua-xiu|Pan, Jin-shui
PMID: 16174594
Journal: Bull Cancer. 2005 Sep;92(9):773-81.
Title: [Trefoil factor 1 (pS2/TFF1), a peptide with numerous functions].
Author: Mathelin, Carole|Tomasetto, Catherine|Rio, Marie-Christine
PMID: 16203267
Journal: World J Gastroenterol. 2005 Dec 21;11(47):7405-12.
Title: Gene expression profiling of gastric cancer by microarray combined with laser capture microdissection.
Author: Wu, Ming-Shiang|Lin, Yi-Shing|Chang, Yu-Ting|Shun, Chia-Tung|Lin, Ming-Tsan|Lin, Jaw-Town
PMID: 16437709
Journal: Oncogene. 2006 Jan 26;25(4):643-9.
Title: Overexpression of CEBPbeta correlates with decreased TFF1 in gastric cancer.
Author: Sankpal, N V|Moskaluk, C A|Hampton, G M|Powell, S M
PMID: 16247479
Journal: Cancer Res. 2006 Feb 1;66(3):1346-53.
Title: Cofactor of BRCA1: a novel transcription factor regulator in upper gastrointestinal adenocarcinomas.
Author: McChesney, Patricia A|Aiyar, Sarah E|Lee, Ok-Jae|Zaika, Alexander|Moskaluk, Christopher|Li, Rong|El-Rifai, Wa'el
PMID: 16452188
Journal: Mod Pathol. 2006 Apr;19(4):564-72.
Title: Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers.
Author: Milne, Anya N A|Carvalho, Ralph|Morsink, Folkert M|Musler, Alex R|de Leng, Wendy W J|Ristimaki, Ari|Offerhaus, G Johan A
PMID: 16474375
Journal: Gastroenterology. 2006 May;130(6):1696-706.
Title: Trefoil factor family-1 mutations enhance gastric cancer cell invasion through distinct signaling pathways.
Author: Yio, Xianyang|Diamond, Matthew|Zhang, Jie-Yu|Weinstein, Harel|Wang, Lu-Hai|Werther, Lawrence|Itzkowitz, Steven
PMID: 16697734
Journal: World J Gastroenterol. 2006 May 21;12(19):3119-22.
Title: Expression of trefoil factors 1 and 2 in precancerous condition and gastric cancer.
Author: Shi, Shu-Qing|Cai, Jian-Ting|Yang, Jian-Ming
PMID: 16718800
Journal: Oncol Rep. 2006 Aug;16(2):411-6.
Title: Detection of lymph node micrometastasis in pN0 early gastric cancer: efficacy of duplex RT-PCR with MUC2 and TFF1 in mucosal cancer.
Author: Sonoda, Hiromichi|Yamamoto, Kazuo|Kushima, Ryoji|Yamamoto, Hiroshi|Naitoh, Hiroyuki|Okabe, Hidetoshi|Tani, Tohru
PMID: 16820924
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2006 Aug;26(8):1234-6.
Title: [Molecular forms of TFF1 in normal gastric mucosa and its relationship with canceration].
Author: Ren, Jian-lin|Luo, Jin-yan|Lu, Ya-pi|Wang, Lin|Chen, Jian-min|Liu, Ming|Shi, Hua-xiu
PMID: 16939928
Journal: World J Gastroenterol. 2006 Dec 7;12(45):7361-4.
Title: Molecular forms of trefoil factor 1 in normal gastric mucosa and its expression in normal and abnormal gastric tissues.
Author: Ren, Jian-Lin|Luo, Jin-Yan|Lu, Ya-Pi|Wang, Lin|Shi, Hua-Xiu
PMID: 17143957
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G1-5. Epub 2006 Aug 24.
Title: Differentiation of the Gastric Mucosa IV. Role of trefoil peptides and IL-6 cytokine family signaling in gastric homeostasis.
Author: Giraud, A S|Jackson, C|Menheniott, T R|Judd, L M
PMID: 16935852
Journal: Ann Surg Oncol. 2007 May;14(5):1694-702. Epub 2007 Feb 9.
Title: Detection of minimal gastric cancer cells in peritoneal washings by focused microarray analysis with multiple markers: clinical implications.
Author: Mori, Kazuhiko|Suzuki, Tomohiro|Uozaki, Hiroshi|Nakanishi, Hayao|Ueda, Tetsuya|Matsuno, Yoshihiro|Kodera, Yasuhiro|Sakamoto, Hiromi|Yamamoto, Nobuko|Sasako, Mitsuru|Kaminishi, Michio|Sasaki, Hiroki
PMID: 17294072
Journal: Hum Pathol. 2007 Jun;38(6):903-13. Epub 2007 Mar 21.
Title: Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis.
Author: Milne, Anya N A|Sitarz, Robert|Carvalho, Ralph|Polak, Mirjam M|Ligtenberg, Marjolijn|Pauwels, Patrick|Offerhaus, G Johan A|Weterman, Marian A J
PMID: 17376510
Journal: J Gastroenterol Hepatol. 2007 Jun;22(6):936-42.
Title: Up-regulation of TFF1 (pS2) expression by TNF-alpha in gastric epithelial cells.
Author: Koike, Takero|Shimada, Tadahito|Fujii, Yoichiro|Chen, Guozhong|Tabei, Kyoko|Namatame, Takashi|Yamagata, Michiko|Tajima, Akihiro|Yoneda, Masashi|Terano, Akira|Hiraishi, Hideyuki
PMID: 17565651
Journal: Clin Cancer Res. 2008 Jul 1;14(13):4161-7.
Title: Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: influence of tumor histology and relationship to prognosis.
Author: Moss, Steven F|Lee, Jin-Woo|Sabo, Edmond|Rubin, Anna K|Rommel, John|Westley, Bruce R|May, Felicity E B|Gao, John|Meitner, Patricia A|Tavares, Rose|Resnick, Murray B
PMID: 18593995
Journal: Biochem Biophys Res Commun. 2008 Nov 21;376(3):573-7.
Title: Induction of follistatin precedes gastric transformation in gastrin deficient mice.
Author: Kang, Weiqun|Saqui-Salces, Milena|Zavros, Yana|Merchant, Juanita L
PMID: 18804092
Journal: Scand J Gastroenterol. 2008 Jan;43(1):25-33.
Title: Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in human gastric carcinoma cells.
Author: Matsuda, Kazuyuki|Yamauchi, Kazuyoshi|Matsumoto, Takehisa|Sano, Kenji|Yamaoka, Yoshio|Ota, Hiroyoshi
PMID: 18938748
Journal: Int J Biochem Cell Biol. 2009 Mar;41(3):632-40.
Title: The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer.
Author: May, Felicity E B|Griffin, S Michael|Westley, Bruce R
PMID: 18722547
Journal: Hum Pathol. 2009 Mar;40(3):314-22.
Title: Comparative analysis of protein expressions in primary and metastatic gastric carcinomas.
Author: Kim, Ji Hun|Kim, Min A|Lee, Hye Seung|Kim, Woo Ho
PMID: 18835621
Journal: Differentiation. 2009 Apr;77(4):412-23.
Title: Eupatilin exhibits a novel anti-tumor activity through the induction of cell cycle arrest and differentiation of gastric carcinoma AGS cells.
Author: Choi, Eun-Ju|Oh, Hyun-Mee|Wee, Hyun|Choi, Chang-Soo|Choi, Suck-Chei|Kim, Ki-Hoon|Han, Weon-Cheol|Oh, Tae-Young|Kim, Sang-Hyun|Jun, Chang-Duk
PMID: 19281788
Journal: Biochim Biophys Acta. 2009 Nov;1793(11):1623-33.
Title: Cytokine signalling via gp130 in gastric cancer.
Author: Howlett, M|Menheniott, T R|Judd, L M|Giraud, A S
PMID: 19665497
Journal: Front Biosci (Landmark Ed). 2010 Jan 1;15:595-603.
Title: Mouse models demonstrating the role of stem/progenitor cells in gastric carcinogenesis.
Author: Karam, Sherif M
PMID: 20036835
Journal: Lab Invest. 2010 Aug;90(8):1132-9.
Title: C/EBP alpha expression is associated with homeostasis of the gastric epithelium and with gastric carcinogenesis.
Author: Regalo, Goncalo|Resende, Carlos|Wen, Xiaogang|Gomes, Barbara|Duraes, Cecilia|Seruca, Raquel|Carneiro, Fatima|Machado, Jose C
PMID: 20386538
Journal: Gastroenterology. 2010 Dec;139(6):2005-17.
Title: Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.
Author: Peterson, Anthony J|Menheniott, Trevelyan R|O'Connor, Louise|Walduck, Anna K|Fox, James G|Kawakami, Kazuyuki|Minamoto, Toshinari|Ong, Eng Kok|Wang, Timothy C|Judd, Louise M|Giraud, Andrew S
PMID: 20801119
Journal: Infect Agent Cancer. 2010 Dec 31;5:27.
Title: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells.
Author: Ryan, Julie L|Jones, Richard J|Kenney, Shannon C|Rivenbark, Ashley G|Tang, Weihua|Knight, Elizabeth Rw|Coleman, William B|Gulley, Margaret L
PMID: 21194482
Journal: Gastroenterology. 2011 Mar;140(3):879-91.
Title: Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing.
Author: Tomita, Hiroyuki|Takaishi, Shigeo|Menheniott, Trevelyan R|Yang, Xiangdong|Shibata, Wataru|Jin, Guangchun|Betz, Kelly S|Kawakami, Kazuyuki|Minamoto, Toshinari|Tomasetto, Catherine|Rio, Marie-Christine|Lerkowit, Nataporn|Varro, Andrea|Giraud, Andrew S|Wang,
PMID: 21111741
Journal: Exp Mol Pathol. 2011 Apr;90(2):201-9.
Title: Gene expression changes in patient-matched gastric normal mucosa, adenomas, and carcinomas.
Author: Kim, Hyunki|Eun, Jung Woo|Lee, Hanna|Nam, Suk Woo|Rhee, Hwanseok|Koh, Kwi Hye|Kim, Hoguen
PMID: 21185829
Journal: J Gastroenterol. 2011 Jun;46(6):736-45.
Title: The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.
Author: Kaise, Mitsuru|Miwa, Jun|Tashiro, Jun|Ohmoto, Yasukazu|Morimoto, Shingo|Kato, Masayuki|Urashima, Mitsuyoshi|Ikegami, Masahiro|Tajiri, Hisao
PMID: 21455714
Journal: J Clin Invest. 2011 May;121(5):1753-67.
Title: Loss of TFF1 is associated with activation of NF-kappaB-mediated inflammation and gastric neoplasia in mice and humans.
Author: Soutto, Mohammed|Belkhiri, Abbes|Piazuelo, M Blanca|Schneider, Barbara G|Peng, Dunfa|Jiang, Aixiang|Washington, M Kay|Kokoye, Yasin|Crowe, Sheila E|Zaika, Alexander|Correa, Pelayo|Peek, Richard M Jr|El-Rifai, Wael
PMID: 21490402
Journal: Gastroenterology. 2011 Sep;141(3):837-845.e1-7.
Title: Tests for serum levels of trefoil factor family proteins can improve gastric cancer screening.
Author: Aikou, Susumu|Ohmoto, Yasukazu|Gunji, Toshiaki|Matsuhashi, Nobuyuki|Ohtsu, Hiroshi|Miura, Hirona|Kubota, Kensuke|Yamagata, Yukinori|Seto, Yasuyuki|Nakajima, Atsushi|Goldenring, James R|Kaminishi, Michio|Nomura, Sachiyo
PMID: 21699780
Journal: Helicobacter. 2011 Sep;16 Suppl 1:38-44.
Title: Gastric cancer: basic aspects.
Author: Resende, Carlos|Thiel, Alexandra|Machado, Jose C|Ristimaki, Ari
PMID: 21896084
Journal: Mol Cell Biochem. 2012 Jan;359(1-2):369-74.
Title: Gastrointestinal tract specific gene GDDR inhibits the progression of gastric cancer in a TFF1 dependent manner.
Author: Chu, Guanghui|Qi, Shengbin|Yang, Guodong|Dou, Kefeng|Du, Jianjun|Lu, Zifan
PMID: 21870107
Journal: Int J Cancer. 2012 Sep 1;131(5):1032-41.
Title: Inhibition of cyclooxygenase-2 causes regression of gastric adenomas in trefoil factor 1 deficient mice.
Author: Thiel, Alexandra|Narko, Kirsi|Heinonen, Mira|Hemmes, Annabrita|Tomasetto, Catherine|Rio, Marie-Christine|Haglund, Caj|Makela, Tomi P|Ristimaki, Ari
PMID: 22034055
Journal: Gene. 2012 Jan 15;492(1):100-3.
Title: Polymorphism of estrogen response element in TFF1 gene promoter is associated with an increased susceptibility to gastric cancer.
Author: Moghanibashi, Mehdi|Mohamadynejad, Parisa|Rasekhi, Maryam|Ghaderi, Abbas|Mohammadianpanah, Mohammad
PMID: 22093877
Journal: Jpn J Clin Oncol. 2012 Feb;42(2):148-52.
Title: Analysis for the combination expression of CK20, FABP1 and MUC2 is sensitive for the prediction of peritoneal recurrence in gastric cancer.
Author: Satoh, Yumiko|Mori, Kazuhiko|Kitano, Kentaro|Kitayama, Joji|Yokota, Hiromitsu|Sasaki, Hiroki|Uozaki, Hiroshi|Fukayama, Masashi|Seto, Yasuhiro|Nagawa, Hirokazu|Yatomi, Yutaka|Takai, Daiya
PMID: 22172348
Journal: Bosn J Basic Med Sci. 2012 May;12(2):74-81.
Title: TFF1 inhibits proliferation and induces apoptosis of gastric cancer cells in vitro.
Author: Ge, Yanli|Zhang, Junjie|Cao, Jianchun|Wu, Qiong|Sun, Longe|Guo, Likun|Wang, Zhirong
PMID: 22642590
Journal: Oncol Rep. 2012 Oct;28(4):1257-62.
Title: Role of trefoil factor 1 in gastric cancer and relationship between trefoil factor 1 and gastrokine 1.
Author: Mao, Wei|Chen, Jie|Peng, Tie-Li|Yin, Xiao-Fei|Chen, Lian-Zhou|Chen, Min-Hu
PMID: 22842654
Journal: Zhonghua Yi Xue Za Zhi. 2012 Jun 12;92(22):1540-3.
Title: [Expression and significance of trefoil factor 1 protein and serum pepsinogen in benign and malignant gastric ulcers].
Author: Yang, Jun|Li, Chao-xi|Dai, Yi-yang|Peng, Fang|Weng, Xiu-mei|Ji, Mu-xi
PMID: 22944057
Journal: Gastric Cancer. 2013 Jul;16(3):329-37.
Title: Influence of Helicobacter pylori status and eradication on the serum levels of trefoil factors and pepsinogen test: serum trefoil factor 3 is a stable biomarker.
Author: Kaise, Mitsuru|Miwa, Jun|Fujimoto, Ai|Tashiro, Jun|Tagami, Daisuke|Sano, Hiromi|Ohmoto, Yasukazu
PMID: 22907485
Journal: Genes Chromosomes Cancer. 2013 Mar;52(3):237-49.
Title: A set of specific miRNAs is connected with murine and human gastric cancer.
Author: Shah, Aftab Ali|Leidinger, Petra|Backes, Christina|Keller, Andreas|Karpinski, Pawel|Sasiadek, Maria M|Blin, Nikolaus|Meese, Eckart
PMID: 23124995
Journal: Int J Oncol. 2013 Mar;42(3):894-902.
Title: Loss of trefoil factor 1 is regulated by DNA methylation and is an independent predictive factor for poor survival in advanced gastric cancer.
Author: Tanaka, Tomokazu|Nakamura, Jun|Kitajima, Yoshihiko|Kai, Keita|Miyake, Shuusuke|Hiraki, Masatsugu|Ide, Takao|Koga, Yasuo|Noshiro, Hirokazu
PMID: 23291975
Journal: Int J Med Sci. 2013;10(2):133-40.
Title: Reduced expression of TFF1 and increased expression of TFF3 in gastric cancer: correlation with clinicopathological parameters and prognosis.
Author: Im, Soyoung|Yoo, Changyoung|Jung, Ji-Han|Choi, Hyun Joo|Yoo, Jinyoung|Kang, Chang Suk
PMID: 23329884
Journal: Virchows Arch. 2013 Oct;463(4):497-507.
Title: Activation of the NF-kB pathway downregulates TFF-1 in gastric carcinogenesis.
Author: Cobler, Lara|Mejias-Luque, Raquel|Garrido, Marta|Pera, Manuel|Badia-Garrido, Enric|de Bolos, Carme
PMID: 23942618
Journal: Gastroenterology. 2013 Dec;145(6):1312-22.e1-8.
Title: Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia.
Author: Katsha, Ahmed|Soutto, Mohammed|Sehdev, Vikas|Peng, Dunfa|Washington, M Kay|Piazuelo, M Blanca|Tantawy, Mohammed N|Manning, H Charles|Lu, Pengcheng|Shyr, Yu|Ecsedy, Jeffrey|Belkhiri, Abbes|El-Rifai, Wael
PMID: 23993973
Journal: J Surg Oncol. 2013 Nov;108(6):409-13.
Title: COX-2, TFF1, and Src define better prognosis in young patients with gastric cancer.
Author: Schildberg, Claus|Abbas, M|Merkel, S|Agaimy, A|Dimmler, A|Schlabrakowski, A|Croner, R|Leupolt, J|Hohenberger, W|Allgayer, H
PMID: 24037722
Journal: Cancers (Basel). 2013 Jan 24;5(1):92-130.
Title: Mouse models of gastric cancer.
Author: Hayakawa, Yoku|Fox, James G|Gonda, Tamas|Worthley, Daniel L|Muthupalani, Sureshkumar|Wang, Timothy C
PMID: 24216700
Journal: PLoS One. 2013 Nov 13;8(11):e79455.
Title: Copper promotes TFF1-mediated Helicobacter pylori colonization.
Author: Montefusco, Sandro|Esposito, Roberta|D'Andrea, Luca|Monti, Maria Chiara|Dunne, Ciara|Dolan, Brendan|Tosco, Alessandra|Marzullo, Liberato|Clyne, Marguerite
PMID: 24236136
Journal: Tumori. 2013 Nov-Dec;99(6):702-7.
Title: Trefoil factor 1 gene alternations and expression in colorectal carcinomas.
Author: Huang, You-Guang|Li, Yun-Feng|Pan, Bao-Long|Wang, Li-Ping|Zhang, Yong|Lee, Wen-Hui|Zhang, Yun
PMID: 24503794
Journal: Mol Med Rep. 2014 Jan;9(1):109-17.
Title: DNA methylation of trefoil factor 1 (TFF1) is associated with the tumorigenesis of gastric carcinoma.
Author: Feng, Guoxun|Zhang, Yan|Yuan, Huisheng|Bai, Rixing|Zheng, Jianwei|Zhang, Jinqian|Song, Maomin
PMID: 24190027
Journal: Tumour Biol. 2014 May;35(5):4199-207.
Title: Gastrokine-2 is downregulated in gastric cancer and its restoration suppresses gastric tumorigenesis and cancer metastasis.
Author: Dai, Jin|Zhang, Ning|Wang, Jinhui|Chen, Minhu|Chen, Jie
PMID: 24408014
Journal: Cancer Lett. 2014 May 28;347(1):98-104.
Title: miRNA423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 in gastric cancer cells.
Author: Liu, Jingjing|Wang, Xu|Yang, Xiaoning|Liu, Yunpeng|Shi, Ying|Ren, Jianlin|Guleng, Bayasi
PMID: 24486742
Journal: Cancer Prev Res (Phila). 2014 Jun;7(6):585-95.
Title: Slow overmethylation of housekeeping genes in the body mucosa is associated with the risk for gastric cancer.
Author: Oh, Jung-Hwan|Rhyu, Mun-Gan|Jung, Sung-Hoon|Choi, Sang-Wook|Kim, Suk-Il|Hong, Seung-Jin
PMID: 24654229
Journal: BMC Gastroenterol. 2014 Apr 11;14:74.
Title: Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China.
Author: Huang, Zhigang|Zhang, Xie|Lu, Hongna|Wu, Lina|Wang, Danping|Zhang, Qiubo|Ding, Huaxin
PMID: 24720760
Journal: Dig Dis Sci. 2014 Jul;59(7):1428-35.
Title: Piezo1 is as a novel trefoil factor family 1 binding protein that promotes gastric cancer cell mobility in vitro.
Author: Yang, Xiao-Ning|Lu, Ya-Pi|Liu, Jing-Jing|Huang, Jian-Kun|Liu, Yun-Peng|Xiao, Chuan-Xing|Jazag, Amarsanaa|Ren, Jian-Lin|Guleng, Bayasi
PMID: 24798994
Journal: Oncotarget. 2014 Jul 30;5(14):5663-73.
Title: TFF1 activates p53 through down-regulation of miR-504 in gastric cancer.
Author: Soutto, Mohammed|Chen, Zheng|Saleh, Mohamed A|Katsha, Ahmed|Zhu, Shoumin|Zaika, Alexander|Belkhiri, Abbes|El-Rifai, Wael
PMID: 25015107
Journal: Gut. 2015 Jul;64(7):1028-39.
Title: Activation of beta-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis.
Author: Soutto, Mohammed|Peng, DunFa|Katsha, Ahmed|Chen, Zheng|Piazuelo, Maria Blanca|Washington, Mary Kay|Belkhiri, Abbes|Correa, Pelayo|El-Rifai, Wael
PMID: 25107557
Journal: Biochim Biophys Acta. 2015 May;1852(5):970-9.
Title: miR218-5p regulates the proliferation of gastric cancer cells by targeting TFF1 in an Erk1/2-dependent manner.
Author: Shi, Ying|Chen, Guo-Bin|Huang, Qing-Wen|Chen, Xu|Liu, Jing-Jing|Xu, Wei|Huang, Xiao-Xiao|Liu, Yun-Peng|Xiao, Chuan-Xing|Wu, Deng-Chyang|Guleng, Bayasi|Ren, Jian-Lin
PMID: 25652124
Journal: Oncotarget. 2015 Jul 20;6(20):17911-22.
Title: Loss of TFF1 promotes Helicobacter pylori-induced beta-catenin activation and gastric tumorigenesis.
Author: Soutto, Mohammed|Romero-Gallo, Judith|Krishna, Uma|Piazuelo, M Blanca|Washington, M Kay|Belkhiri, Abbes|Peek, Richard M Jr|El-Rifai, Wael
PMID: 25980439
Journal: J Korean Med Sci. 2015 Aug;30(8):1035-41.
Title: Association between Promoter Polymorphisms of TFF1, TFF2, and TFF3 and the Risk of Gastric and Diffuse Gastric Cancers in a Korean Population.
Author: Jin, Eun-Heui|Lee, Sang-Il|Kim, JaeWoo|Seo, Eun Young|Lee, Su Yel|Hur, Gang Min|Shin, Sanghee|Hong, Jang Hee
PMID: 26240479
Journal: Clin Chim Acta. 2015 Oct 23;450:127-34.
Title: Trefoil factors: Gastrointestinal-specific proteins associated with gastric cancer.
Author: Xiao, Ping|Ling, Hui|Lan, Gang|Liu, Jiao|Hu, Haobin|Yang, Ruirui
PMID: 26265233
Journal: Cancer. 2015 Dec 15;121(24):4348-58.
Title: Trefoil factor 1 expression suppresses Helicobacter pylori-induced inflammation in gastric carcinogenesis.
Author: Soutto, Mohammed|Chen, Zheng|Katsha, Ahmed M|Romero-Gallo, Judith|Krishna, Uma S|Piazuelo, M Blanca|Washington, M Kay|Peek, Richard M Jr|Belkhiri, Abbes|El-Rifai, Wael M
PMID: 26372254
Journal: Oncotarget. 2015 Nov 3;6(34):35579-88.
Title: Wnt/beta-catenin, an oncogenic pathway targeted by H. pylori in gastric carcinogenesis.
Author: Song, Xiaowen|Xin, Na|Wang, Wei|Zhao, Chenghai
PMID: 26417932
Journal: Int J Clin Exp Pathol. 2015 Sep 1;8(9):10412-9. eCollection 2015.
Title: Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/beta-catenin signaling.
Author: Zhao, Shan|Ma, Yumei|Huang, Xianghua
PMID: 26617749
Journal: Cancer Res. 2016 Apr 15;76(8):2277-87.
Title: Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.
Author: Thiem, Stefan|Eissmann, Moritz F|Elzer, Joachim|Jonas, Anna|Putoczki, Tracy L|Poh, Ashleigh|Nguyen, Paul|Preaudet, Adele|Flanagan, Dustin|Vincan, Elizabeth|Waring, Paul|Buchert, Michael|Jarnicki, Andrew|Ernst, Matthias
PMID: 26837764
Journal: J Mol Med (Berl). 2016 Dec;94(12):1385-1395.
Title: C/EBPbeta regulates homeostatic and oncogenic gastric cell proliferation.
Author: Regalo, Goncalo|Forster, Susann|Resende, Carlos|Bauer, Bianca|Fleige, Barbara|Kemmner, Wolfgang|Schlag, Peter M|Meyer, Thomas F|Machado, Jose C|Leutz, Achim
PMID: 27522676
Journal: Int J Mol Sci. 2016 Sep 2;17(9). pii: ijms17091467.
Title: Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer.
Author: Wu, Cheng-Shyong|Wei, Kuo-Liang|Chou, Jian-Liang|Lu, Chung-Kuang|Hsieh, Ching-Chuan|Lin, Jora M J|Deng, Yi-Fang|Hsu, Wan-Ting|Wang, Hui-Min David|Leung, Chung-Hang|Ma, Dik-Lung|Li, Chin|Chan, Michael W Y
PMID: 27598141
Journal: Gastric Cancer. 2017 Sep;20(5):772-783.
Title: Heterodimeric interaction between GKN2 and TFF1 entails synergistic antiproliferative and pro-apoptotic effects on gastric cancer cells.
Author: Kim, Olga|Yoon, Jung Hwan|Choi, Won Suk|Ashktorab, Hassan|Smoot, Duane T|Nam, Suk Woo|Lee, Jung Young|Park, Won Sang
PMID: 28150071
Journal: Genes Chromosomes Cancer. 2017 Jul;56(7):535-547.
Title: Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia.
Author: Chen, Zheng|Soutto, Mohammed|Rahman, Bushra|Fazili, Muhammad W|Peng, DunFa|Blanca Piazuelo, Maria|Chen, Heidi|Kay Washington, M|Shyr, Yu|El-Rifai, Wael
PMID: 28281307
Journal: Front Med (Lausanne). 2017 May 2;4:47.
Title: Genetic Alterations in Gastric Cancer Associated with Helicobacter pylori Infection.
Author: Rivas-Ortiz, Claudia I|Lopez-Vidal, Yolanda|Arredondo-Hernandez, Luis Jose Rene|Castillo-Rojas, Gonzalo
PMID: 28512631
Journal: Pathol Int. 2017 Aug;67(8):398-403.
Title: Differences between gastric signet-ring cell carcinoma and poorly differentiated adenocarcinoma: A comparison of histopathologic features determined by mucin core protein and trefoil factor family peptide immunohistochemistry.
Author: Fujimoto, Ai|Ishikawa, Yukio|Ishii, Toshiharu|Yamada, Akihiro|Igarashi, Yoshinori|Ohmoto, Yasukazu|Kaise, Mitsuru
PMID: 28691258
Journal: J Cancer. 2017 Jul 22;8(13):2424-2435.
Title: Loss of Tff1 Promotes Pro-Inflammatory Phenotype with Increase in the Levels of RORgammat+ T Lymphocytes and Il-17 in Mouse Gastric Neoplasia.
Author: Soutto, Mohammed|Saleh, Mohamed|Arredouani, Mohamed S|Piazuelo, Blanca|Belkhiri, Abbes|El-Rifai, Wael
PMID: 28900479
Journal: Mol Carcinog. 2018 Jul 23.
Title: TFF1 antagonizes TIMP-1 mediated proliferative functions in gastric cancer.
Author: Omar, Omar M|Soutto, Mohammed|Bhat, Nadeem S|Bhat, Ajaz A|Lu, Heng|Chen, Zheng|El-Rifai, Wael
PMID: 28977972
Journal: Mol Cancer Res. 2018 Apr;16(4):696-706.
Title: Methylation of the HOXA10 Promoter Directs miR-196b-5p-Dependent Cell Proliferation and Invasion of Gastric Cancer Cells.
Author: Shao, Linlin|Chen, Zheng|Peng, Dunfa|Soutto, Mohammed|Zhu, Shoumin|Bates, Andreia|Zhang, Shutian|El-Rifai, Wael
PMID: 29453320
Journal: Mol Carcinog. 2018 Jul 23.
Title: TFF1 antagonizes TIMP-1 mediated proliferative functions in gastric cancer.
Author: Omar, Omar M|Soutto, Mohammed|Bhat, Nadeem S|Bhat, Ajaz A|Lu, Heng|Chen, Zheng|El-Rifai, Wael
PMID: 30035371
Journal: Dig Dis Sci. 2018 Aug 6. pii: 10.1007/s10620-018-5223-0.
Title: Effect of Helicobacter pylori Infection on GATA-5 and TFF1 Regulation, Comparison Between Pediatric and Adult Patients.
Author: Alvarez, Marisa Claudia|Fernandes, Julien|Michel, Valerie|Touati, Eliette|Ribeiro, Marcelo Lima
PMID: 30083861
Journal: J Pathol. 2018 Aug 31.
Title: Three types of metaplasia models through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium.
Author: Kinoshita, Hiroto|Hayakawa, Yoku|Konishi, Mitsuru|Hata, Masahiro|Tsuboi, Mayo|Hayata, Yuki|Hikiba, Yohko|Ihara, Sozaburo|Nakagawa, Hayato|Ikenoue, Tsuneo|Ushiku, Tetsuo|Fukayama, Masashi|Hirata, Yoshihiro|Koike, Kazuhiko
PMID: 30168144