Primary Site >> Liver Cancer

Gene >> TERT

Journal: Gan. 1982 Aug;73(4):642-8.
Title: Antitumor effect and structure-activity relationship of asterriquinone analogs.
Author: Shimizu, S|Yamamoto, Y|Inagaki, J|Koshimura, S
PMID: 7152200
Journal: Crit Rev Toxicol. 1985;15(2):109-50.
Title: Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants.
Author: Ito, N|Fukushima, S|Tsuda, H
PMID: 3899519
Journal: Environ Health Perspect. 1994 Jan;102 Suppl 1:255-64.
Title: Dose-response relationship in multistage carcinogenesis: promoters.
Author: Kitchin, K T|Brown, J L|Setzer, R W
PMID: 8187717
Journal: Cancer Res. 1996 Apr 15;56(8):1786-93.
Title: Mechanism of oxidative DNA damage induced by delta-aminolevulinic acid in the presence of copper ion.
Author: Hiraku, Y|Kawanishi, S
PMID: 8620494
Journal: Nat Genet. 1998 Jan;18(1):65-8.
Title: Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas.
Author: Nakayama, J|Tahara, H|Tahara, E|Saito, M|Ito, K|Nakamura, H|Nakanishi, T|Tahara, E|Ide, T|Ishikawa, F
PMID: 9425903
Journal: J Biol Chem. 2000 Nov 24;275(47):36671-5.
Title: NF-kappa B regulates transcription of the mouse telomerase catalytic subunit.
Author: Yin, L|Hubbard, A K|Giardina, C
PMID: 10970902
Journal: Zhonghua Gan Zang Bing Za Zhi. 2002 Apr;10(2):97-9.
Title: [Reversing malignant phenotypes of liver cancer cell lines with antisense gene to human telomerase reverse transcriptase].
Author: Yang, Shiming|Fang, Dianchun|Liu, Aimin|Yang, Jinliang|Luo, Yuanhui|Lu, Rong|Liu, Weiwen
PMID: 11983122
Journal: Gene Ther. 2003 Aug;10(15):1241-7.
Title: Telomerase-dependent oncolytic adenovirus for cancer treatment.
Author: Huang, T-G|Savontaus, M J|Shinozaki, K|Sauter, B V|Woo, S L C
PMID: 12858189
Journal: J Med Chem. 2003 Jul 31;46(16):3502-7.
Title: Monofunctional platinum complexes showing potent cytotoxicity against human liver carcinoma cell line BEL-7402.
Author: Zhang, Junyong|Wang, Xiaoyong|Tu, Chao|Lin, Jun|Ding, Jian|Lin, Liping|Wang, Zheming|He, Cheng|Yan, Chunhua|You, Xiaozeng|Guo, Zijian
PMID: 12877588
Journal: Cell Signal. 2004 Oct;16(10):1141-51.
Title: Protein kinase A inhibits lysophosphatidic acid induction of serum response factor via alterations in the actin cytoskeleton.
Author: Nguyen, Giang Huong|French, Robert|Radhakrishna, Harish
PMID: 15240009
Journal: Zhonghua Gan Zang Bing Za Zhi. 2004 Aug;12(8):500.
Title: [Expression and clinical significance of telomerase hTRT in primary hepatocellular carcinoma].
Author: Zhou, Yong-jian|Zhang, Xiang-fu|Lu, Hui-shan|Huang, Chang-ming|Yang, Fa-duan|Wang, Chuan
PMID: 15329219
Journal: Hepatogastroenterology. 2005 Sep-Oct;52(65):1325-8.
Title: Preoperative human-telomerase reverse transcriptase mRNA in peripheral blood and tumor recurrence in living-related liver transplantation for hepatocellular carcinoma.
Author: Sato, Yoshinobu|Yamamoto, Satoshi|Oya, Hiroshi|Nakatsuka, Hideki|Kobayashi, Takashi|Takeishi, Toshiyuki|Hirano, Kenichiro|Hara, Yoshiaki|Watanabe, Takaoki|Waguri, Nobuo|Suda, Takeshi|Ichida, Takafumi|Aoyagi, Yutaka|Hatakeyama, Katsuyoshi
PMID: 16201066
Journal: Int J Oncol. 2006 Mar;28(3):715-22.
Title: In vitro RNA interference against beta-catenin inhibits the proliferation of pediatric hepatic tumors.
Author: Sangkhathat, Surasak|Kusafuka, Takeshi|Miao, Jiangyong|Yoneda, Akihiro|Nara, Keigo|Yamamoto, Seiji|Kaneda, Yasafumi|Fukuzawa, Masahiro
PMID: 16465377
Journal: Mol Ther. 2006 May;13(5):918-27.
Title: Immune gene-viral therapy with triplex efficacy mediated by oncolytic adenovirus carrying an interferon-gamma gene yields efficient antitumor activity in immunodeficient and immunocompetent mice.
Author: Su, Changqing|Peng, Linhui|Sham, Jonathan|Wang, Xinghua|Zhang, Qi|Chua, Daniel|Liu, Chen|Cui, Zhenfu|Xue, Huibin|Wu, Hongping|Yang, Qin|Zhang, Baihe|Liu, Xinyuan|Wu, Mengchao|Qian, Qijun
PMID: 16497559
Journal: Zhonghua Gan Zang Bing Za Zhi. 2006 Apr;14(4):272-6.
Title: [A preliminary study on anti-liver cancer immunity of the virus-like particulate peptide-nucleic acid vaccine].
Author: Guo, Hong|Hao, Jia|Wu, Chao|Fang, Dian-chun
PMID: 16635296
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2006 Jun;26(6):821-3.
Title: [Expressions of h-TERT, c-myc, PCNA and cell apoptosis in liver carcinogenesis].
Author: Fu, Xiao-mei|Yang, Qing-xu|Shao, Chun-kui|Feng, Zhi-ying
PMID: 16793609
Journal: Gastroenterology. 2006 Dec;131(6):1758-67.
Title: A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.
Author: Llovet, Josep M|Chen, Yingbei|Wurmbach, Elisa|Roayaie, Sasan|Fiel, M Isabel|Schwartz, Myron|Thung, Swan N|Khitrov, Gregory|Zhang, Weijia|Villanueva, Augusto|Battiston, Carlo|Mazzaferro, Vincenzo|Bruix, Jordi|Waxman, Samuel|Friedman, Scott L
PMID: 17087938
Journal: Transplant Proc. 2006 Dec;38(10):3636-9.
Title: Comparison between human-telomerase reverse transcriptase mRNA and alpha-fetoprotein mRNA as a predictive value for recurrence of hepatocellular carcinoma in living donor liver transplantation.
Author: Oya, H|Sato, Y|Yamamoto, S|Nakatsuka, H|Kobayashi, T|Hara, Y|Waguri, N|Suda, T|Aoyagi, Y|Hatakeyama, K
PMID: 17175353
Journal: Cancer Biol Ther. 2007 Nov;6(11):1726-32. Epub 2007 Aug 1.
Title: The oncolytic adenovirus targeting to TERT and RB pathway induced specific and potent anti-tumor efficacy in vitro and in vivo for hepatocellular carcinoma.
Author: Zhang, Wei|Cai, Rong|Luo, Jingjing|Wang, Yingxin|Cui, Qiang|Wei, Xubin|Zhang, Hongfeng|Qian, Cheng
PMID: 18281783
Journal: Eur J Med Chem. 2008 Jul;43(7):1499-505.
Title: Syntheses and cytotoxicities of the analogues of the taxoid brevifoliol.
Author: Chattopadhyay, Sunil K|Tripathi, Sarita|Darokar, Mahendra P|Faridi, Uzma|Sisodia, Brijesh|Negi, Shubhra|Kotesh Kumar, J|Khanuja, Suman P S
PMID: 17950495
Journal: Clin Cancer Res. 2009 Nov 15;15(22):6810-9.
Title: Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.
Author: Mai, Wei|Kawakami, Kazuyuki|Shakoori, Abbas|Kyo, Satoru|Miyashita, Katsuyoshi|Yokoi, Kenji|Jin, Mingji|Shimasaki, Takeo|Motoo, Yoshiharu|Minamoto, Toshinari
PMID: 19903789
Journal: Free Radic Res. 2010 Jan;44(1):108-17.
Title: Anti-cancer activity of nitrones in the Apc(Min/+) model of colorectal cancer.
Author: Floyd, Robert A|Towner, Rheal A|Wu, Dee|Abbott, Andrew|Cranford, Rebecca|Branch, Dan|Guo, Wei-Xing|Foster, Steven B|Jones, Inna|Alam, Rajib|Moore, Danny|Allen, Toby|Huycke, Mark
PMID: 19886748
Journal: Neoplasma. 2010;57(3):222-7.
Title: Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesis.
Author: Chen, Y|Kong, Q
PMID: 20353272
Journal: Oncol Rep. 2010 Oct;24(4):1093-9.
Title: beta-catenin siRNA regulation of apoptosis- and angiogenesis-related gene expression in hepatocellular carcinoma cells: potential uses for gene therapy.
Author: Wang, Xin-Hong|Sun, Xun|Meng, Xiang-Wei|Lv, Zhi-Wu|Du, Ya-Ju|Zhu, Yan|Chen, Jing|Kong, De-Xia|Jin, Shi-Zhu
PMID: 20811694
Journal: Zhonghua Gan Zang Bing Za Zhi. 2010 Sep;18(9):672-5.
Title: [The role and significance of Wnt/beta-catenin signaling pathway regulating the signaling molecules in hepatocellular carcinoma].
Author: Wang, Xin-hong|Sun, Xun|Meng, Xiang-wei|Lu, Zhi-wu|Liu, Min-na|Pei, Feng-hua
PMID: 20943078
Journal: J Gastroenterol Hepatol. 2011 Jan;26 Suppl 1:144-52.
Title: Hepatitis B virus x protein in the pathogenesis of hepatitis B virus-induced hepatocellular carcinoma.
Author: Kew, Michael C
PMID: 21199526
Journal: Eur J Pharm Sci. 2011 Mar 18;42(4):387-91.
Title: Combinational RNAi gene therapy of hepatocellular carcinoma by targeting human EGFR and TERT.
Author: Hu, Yurong|Shen, Yingying|Ji, Baofang|Wang, Lei|Zhang, Zhenzhong|Zhang, Yun
PMID: 21238587
Journal: Neoplasma. 2011;58(2):158-71.
Title: Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy.
Author: Wang, X H|Liu, B R|Qu, B|Xing, H|Gao, S L|Yin, J M|Wang, X F|Cheng, Y Q
PMID: 21275467
Journal: Cancer Res. 2011 Jun 15;71(12):4138-49.
Title: Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth.
Author: Chen, Juan|Zhang, Bin|Wong, Nathalie|Lo, Anthony W I|To, Ka-Fai|Chan, Anthony W H|Ng, Margaret H L|Ho, Cecilia Y S|Cheng, Suk-Hang|Lai, Paul B S|Yu, Jun|Ng, Ho-Keung|Ling, Ming-Tat|Huang, Ai-Long|Cai, Xue-Fei|Ko, Ben C B
PMID: 21527554
Journal: Mol Ther. 2011 Aug;19(8):1521-8.
Title: Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways.
Author: Chen, Lizao|Zheng, Jianming|Zhang, Yan|Yang, Luxi|Wang, Jiaqi|Ni, Jian|Cui, Daxiang|Yu, Chaoqin|Cai, Zailong
PMID: 21610700
Journal: Zhonghua Yu Fang Yi Xue Za Zhi. 2011 Jul;45(7):593-6.
Title: [The relationship between gene polymorphism of telomerase reverse transcriptase and susceptibility to hepatocellular carcinoma].
Author: Ding, Chen-Yue|Hu, Ling-Min|Hu, Zhi-Bin|Shen, Hong-Bing
PMID: 22041560
Journal: Nat Genet. 2012 May 27;44(7):765-9.
Title: Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma.
Author: Sung, Wing-Kin|Zheng, Hancheng|Li, Shuyu|Chen, Ronghua|Liu, Xiao|Li, Yingrui|Lee, Nikki P|Lee, Wah H|Ariyaratne, Pramila N|Tennakoon, Chandana|Mulawadi, Fabianus H|Wong, Kwong F|Liu, Angela M|Poon, Ronnie T|Fan, Sheung Tat|Chan, Kwong L|Gong, Zhuolin|Hu,
PMID: 22634754
Journal: Nat Genet. 2012 May 27;44(7):760-4.
Title: Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.
Author: Fujimoto, Akihiro|Totoki, Yasushi|Abe, Tetsuo|Boroevich, Keith A|Hosoda, Fumie|Nguyen, Ha Hai|Aoki, Masayuki|Hosono, Naoya|Kubo, Michiaki|Miya, Fuyuki|Arai, Yasuhito|Takahashi, Hiroyuki|Shirakihara, Takuya|Nagasaki, Masao|Shibuya, Tetsuo|Nakano, Kaoru|Wat
PMID: 22634756
Journal: Chem Biol Interact. 2012 Jul 30;199(1):38-48.
Title: Anticancer effect of tert-butyl-2(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxy l-2)-pyrrolidine-1-carboxylic ester on human hepatoma HepG2 cell line.
Author: Guo, Juan|Zhang, Yanjun|Zhang, Jie|Liang, Jun|Zeng, Lihua|Guo, Guozhen
PMID: 22704995
Journal: PLoS One. 2012;7(8):e43147.
Title: Dyskerin overexpression in human hepatocellular carcinoma is associated with advanced clinical stage and poor patient prognosis.
Author: Liu, Bei|Zhang, Jinglei|Huang, Chen|Liu, Hui
PMID: 22912812
Journal: Int J Cancer. 2013 Mar 15;132(6):1451-62.
Title: Telomerase-specific oncolytic adenoviral therapy for orthotopic hepatocellular carcinoma in HBx transgenic mice.
Author: Lin, Wei-Hsiang|Yeh, Shiou-Hwei|Yang, Wan-Jen|Yeh, Kun-Huei|Fujiwara, Toshiyoshi|Nii, Aisuke|Chang, Stanley Shi-Chung|Chen, Pei-Jer
PMID: 22886913
Journal: Genes Chromosomes Cancer. 2013 Mar;52(3):225-36.
Title: The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling.
Author: Zheng, Xin|Gai, Xiaohong|Han, Shaoshan|Moser, Catherine D|Hu, Chunling|Shire, Abdirashid M|Floyd, Robert A|Roberts, Lewis R
PMID: 23109092
Journal: Carcinogenesis. 2013 Apr;34(4):787-98.
Title: Deep sequencing of the hepatitis B virus in hepatocellular carcinoma patients reveals enriched integration events, structural alterations and sequence variations.
Author: Toh, Soo Ting|Jin, Yu|Liu, Lizhen|Wang, Jingbo|Babrzadeh, Farbod|Gharizadeh, Baback|Ronaghi, Mostafa|Toh, Han Chong|Chow, Pierce Kah-Hoe|Chung, Alexander Y-F|Ooi, London L-P-J|Lee, Caroline G-L
PMID: 23276797
Journal: Science. 2013 Feb 22;339(6122):957-9.
Title: Highly recurrent TERT promoter mutations in human melanoma.
Author: Huang, Franklin W|Hodis, Eran|Xu, Mary Jue|Kryukov, Gregory V|Chin, Lynda|Garraway, Levi A
PMID: 23348506
Journal: Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6021-6.
Title: TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Author: Killela, Patrick J|Reitman, Zachary J|Jiao, Yuchen|Bettegowda, Chetan|Agrawal, Nishant|Diaz, Luis A Jr|Friedman, Allan H|Friedman, Henry|Gallia, Gary L|Giovanella, Beppino C|Grollman, Arthur P|He, Tong-Chuan|He, Yiping|Hruban, Ralph H|Jallo, George I|Mand
PMID: 23530248
Journal: J Hepatol. 2013 Oct;59(4):746-52.
Title: Telomere length, TERT and shelterin complex proteins in hepatocellular carcinomas expressing "stemness"-related markers.
Author: Kim, Haeryoung|Yoo, Jeong Eun|Cho, Jai Young|Oh, Bong-Kyeong|Yoon, Yoo-Seok|Han, Ho-Seong|Lee, Hye Seung|Jang, Ja June|Jeong, Sook Hyang|Kim, Jin Wook|Park, Young Nyun
PMID: 23685049
Journal: Genomics. 2013 Oct;102(4):338-44.
Title: HIVID: an efficient method to detect HBV integration using low coverage sequencing.
Author: Li, Weiyang|Zeng, Xi|Lee, Nikki P|Liu, Xiao|Chen, Shengpei|Guo, Bing|Yi, Shang|Zhuang, Xuehan|Chen, Fang|Wang, Guan|Poon, Ronnie T|Fan, Sheung Tat|Mao, Mao|Li, Yingrui|Li, Songgang|Wang, Jun|Jianwang|Xu, Xun|Jiang, Hui|Zhang, Xiuqing
PMID: 23867110
Journal: Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17426-31.
Title: TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism.
Author: Rachakonda, P Sivaramakrishna|Hosen, Ismail|de Verdier, Petra J|Fallah, Mahdi|Heidenreich, Barbara|Ryk, Charlotta|Wiklund, N Peter|Steineck, Gunnar|Schadendorf, Dirk|Hemminki, Kari|Kumar, Rajiv
PMID: 24101484
Journal: PLoS One. 2014 Jan 8;9(1):e84931.
Title: Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells.
Author: Zhang, Bin|Chen, Juan|Cheng, Alfred S L|Ko, Ben C B
PMID: 24416313
Journal: Biochem Biophys Res Commun. 2014 May 2;447(2):358-63.
Title: Positive association of long telomeres with the invasive capacity of hepatocellular carcinoma cells.
Author: Ko, Eunkyong|Jung, Guhung
PMID: 24732358
Journal: Cancer Cell. 2014 Apr 14;25(4):428-41.
Title: Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation.
Author: Pilati, Camilla|Letouze, Eric|Nault, Jean-Charles|Imbeaud, Sandrine|Boulai, Anais|Calderaro, Julien|Poussin, Karine|Franconi, Andrea|Couchy, Gabrielle|Morcrette, Guillaume|Mallet, Maxime|Taouji, Said|Balabaud, Charles|Terris, Benoit|Canal, Frederic|Paradi
PMID: 24735922
Journal: J Hepatol. 2014 Sep;61(3):685-7.
Title: TERT promoter mutations: gatekeeper and driver of hepatocellular carcinoma.
Author: Pinyol, Roser|Tovar, Victoria|Llovet, Josep M
PMID: 24859456
Journal: Int J Surg. 2014;12(7):659-65.
Title: TERT promoter mutation in resectable hepatocellular carcinomas: a strong association with hepatitis C infection and absence of hepatitis B infection.
Author: Chen, Yu-Ling|Jeng, Yung-Ming|Chang, Chih-Ning|Lee, Hsin-Jung|Hsu, Hey-Chi|Lai, Po-Lin|Yuan, Ray-Hwang
PMID: 24866078
Journal: Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2014 Mar;30(2):171-3.
Title: [Expressions of TERT during the development of rat liver cancer under the interventions of oxymatrine and selenium enriched yeast].
Author: Liu, Dan-Dan|Zhi, Li-Juan|Ma, Ming-Xia|Qiao, Dan|Wang, Mei-Juan|Li, An-Qi|Liu, Gu-Ting|Zhang, Yi-Qing|Zhang, Hong-Xu
PMID: 25016875
Journal: Arab J Gastroenterol. 2014 Jun;15(2):68-71.
Title: Human telomerase reverse transcriptase messenger RNA (TERT mRNA) as a tumour marker for early detection of hepatocellular carcinoma.
Author: El-Mazny, Ahmed|Sayed, Mohamed|Sharaf, Sahar
PMID: 25097049
Journal: Hepatology. 2014 Dec;60(6):1983-92.
Title: Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis.
Author: Nault, Jean Charles|Calderaro, Julien|Di Tommaso, Luca|Balabaud, Charles|Zafrani, Elie Serge|Bioulac-Sage, Paulette|Roncalli, Massimo|Zucman-Rossi, Jessica
PMID: 25123086
Journal: J Hepatol. 2014 Dec;61(6):1312-20.
Title: The genomic landscape of hepatoblastoma and their progenies with HCC-like features.
Author: Eichenmuller, Melanie|Trippel, Franziska|Kreuder, Michaela|Beck, Alexander|Schwarzmayr, Thomas|Haberle, Beate|Cairo, Stefano|Leuschner, Ivo|von Schweinitz, Dietrich|Strom, Tim M|Kappler, Roland
PMID: 25135868
Journal: Genome Biol. 2014 Aug 26;15(8):436.
Title: Diverse modes of genomic alteration in hepatocellular carcinoma.
Author: Jhunjhunwala, Suchit|Jiang, Zhaoshi|Stawiski, Eric W|Gnad, Florian|Liu, Jinfeng|Mayba, Oleg|Du, Pan|Diao, Jingyu|Johnson, Stephanie|Wong, Kwong-Fai|Gao, Zhibo|Li, Yingrui|Wu, Thomas D|Kapadia, Sharookh B|Modrusan, Zora|French, Dorothy M|Luk, John M|Seshag
PMID: 25159915
Journal: PLoS One. 2014 Sep 17;9(9):e107149.
Title: Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression.
Author: Nair, Sandhya V G|Ziaullah|Rupasinghe, H P Vasantha
PMID: 25229655
Journal: Virchows Arch. 2014 Dec;465(6):673-7.
Title: Frequency of TERT promoter mutations in primary tumors of the liver.
Author: Quaas, Alexander|Oldopp, Theresa|Tharun, Lars|Klingenfeld, Catina|Krech, Till|Sauter, Guido|Grob, Tobias J
PMID: 25267585
Journal: Asian Pac J Cancer Prev. 2014;15(19):8197-201.
Title: Polymorphisms of TERT and CLPTM1L and the risk of hepatocellular carcinoma in Chinese males.
Author: Su, Ling-Yan|Li, Xue-Lian|Shen, Li|Zhang, Yue|Zhao, Meng-Meng|Yin, Zhi-Hua|Su, Hong-Ying|Zhou, Bao-Sen
PMID: 25339005
Journal: Nat Genet. 2014 Dec;46(12):1267-73.
Title: Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.
Author: Totoki, Yasushi|Tatsuno, Kenji|Covington, Kyle R|Ueda, Hiroki|Creighton, Chad J|Kato, Mamoru|Tsuji, Shingo|Donehower, Lawrence A|Slagle, Betty L|Nakamura, Hiromi|Yamamoto, Shogo|Shinbrot, Eve|Hama, Natsuko|Lehmkuhl, Megan|Hosoda, Fumie|Arai, Yasuhito|Walk
PMID: 25362482
Journal: PLoS One. 2014 Dec 19;9(12):e114263.
Title: Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers.
Author: Shiraishi, Yuichi|Fujimoto, Akihiro|Furuta, Mayuko|Tanaka, Hiroko|Chiba, Ken-ichi|Boroevich, Keith A|Abe, Tetsuo|Kawakami, Yoshiiku|Ueno, Masaki|Gotoh, Kunihito|Ariizumi, Shun-ichi|Shibuya, Tetsuo|Nakano, Kaoru|Sasaki, Aya|Maejima, Kazuhiro|Kitada, Rina|H
PMID: 25526364
Journal: Hepatology. 2015 Jan;61(1):315-25.
Title: Cooperation of C/EBP family proteins and chromatin remodeling proteins is essential for termination of liver regeneration.
Author: Jin, Jingling|Hong, Il-Hwa|Lewis, Kyle|Iakova, Polina|Breaux, Meghan|Jiang, Yanjun|Sullivan, Emily|Jawanmardi, Nicole|Timchenko, Lubov|Timchenko, Nikolai A
PMID: 25043739
Journal: J Hepatol. 2015 Feb;62(2):498-9.
Title: Reply to: "TERT promoter mutation during development of hepatoblastoma to hepatocellular carcinoma".
Author: Kappler, Roland|Leuschner, Ivo|von Schweinitz, Dietrich
PMID: 25450207
Journal: J Hepatol. 2015 Feb;62(2):497.
Title: TERT promoter mutation during development of hepatoblastoma to hepatocellular carcinoma.
Author: Dong, Rui|Zheng, Shan|Dong, Kuiran
PMID: 25450209
Journal: World J Gastroenterol. 2015 Jan 7;21(1):311-7.
Title: Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations.
Author: Cevik, Dilek|Yildiz, Gokhan|Ozturk, Mehmet
PMID: 25574106
Journal: Nucl Med Biol. 2015 Apr;42(4):413-9.
Title: Automated synthesis and PET evaluation of both enantiomers of [(1)(8)F]FMISO.
Author: Revunov, Evgeny|Jorgensen, Jesper T|Jensen, Andreas Ingemann|Hansen, Anders E|Severin, Gregory W|Kjaer, Andreas|Zhuravlev, Fedor
PMID: 25595134
Journal: Nat Commun. 2015 Jan 30;6:6120.
Title: Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity.
Author: Fujimoto, Akihiro|Furuta, Mayuko|Shiraishi, Yuichi|Gotoh, Kunihito|Kawakami, Yoshiiku|Arihiro, Koji|Nakamura, Toru|Ueno, Masaki|Ariizumi, Shun-ichi|Nguyen, Ha Hai|Shigemizu, Daichi|Abe, Tetsuo|Boroevich, Keith A|Nakano, Kaoru|Sasaki, Aya|Kitada, Rina|Maej
PMID: 25636086
Journal: Clin Res Hepatol Gastroenterol. 2015 Oct;39(5):600-9.
Title: Promoter hypermethylation of TERT is associated with hepatocellular carcinoma in the Han Chinese population.
Author: Zhang, Hong|Weng, Xiaoling|Ye, Junyi|He, Lin|Zhou, Daizhan|Liu, Yun
PMID: 25683523
Journal: Nat Genet. 2015 May;47(5):505-511.
Title: Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.
Author: Schulze, Kornelius|Imbeaud, Sandrine|Letouze, Eric|Alexandrov, Ludmil B|Calderaro, Julien|Rebouissou, Sandra|Couchy, Gabrielle|Meiller, Clement|Shinde, Jayendra|Soysouvanh, Frederic|Calatayud, Anna-Line|Pinyol, Roser|Pelletier, Laura|Balabaud, Charles|Lau
PMID: 25822088
Journal: Eur J Cancer. 2015 May;51(8):969-76.
Title: Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
Author: Huang, Dong-Sheng|Wang, Zhaohui|He, Xu-Jun|Diplas, Bill H|Yang, Rui|Killela, Patrick J|Meng, Qun|Ye, Zai-Yuan|Wang, Wei|Jiang, Xiao-Ting|Xu, Li|He, Xiang-Lei|Zhao, Zhong-Sheng|Xu, Wen-Juan|Wang, Hui-Ju|Ma, Ying-Yu|Xia, Ying-Jie|Li, Li|Zhang, Ru-Xuan|Jin,
PMID: 25843513
Journal: Cancer Immunol Immunother. 2015 Oct;64(10):1305-14.
Title: Novel metronomic chemotherapy and cancer vaccine combinatorial strategy for hepatocellular carcinoma in a mouse model.
Author: Tagliamonte, Maria|Petrizzo, Annacarmen|Napolitano, Maria|Luciano, Antonio|Arra, Claudio|Maiolino, Piera|Izzo, Francesco|Tornesello, Maria Lina|Aurisicchio, Luigi|Ciliberto, Gennaro|Buonaguro, Franco M|Buonaguro, Luigi
PMID: 25944003
Journal: Int J Clin Exp Pathol. 2015 Feb 1;8(2):1427-34. eCollection 2015.
Title: Role of ursolic acid chalcone, a synthetic analogue of ursolic acid, in inhibiting the properties of CD133(+) sphere-forming cells in liver stem cells.
Author: Lin, Rui-Xin|Gong, Lu-Lu|Fan, Li-Mei|Zhao, Zhong-Kai|Yang, Shu-Li
PMID: 25973027
Journal: Pathobiology. 2015;82(2):53-7.
Title: Frequency of TERT Promoter Mutations in Prostate Cancer.
Author: Stoehr, Robert|Taubert, Helge|Zinnall, Ulrike|Giedl, Johannes|Gaisa, Nadine T|Burger, Maximilian|Ruemmele, Petra|Hurst, Carolyn D|Knowles, Margaret A|Wullich, Bernd|Hartmann, Arndt
PMID: 25997473
Journal: Gastroenterology. 2015 Oct;149(5):1226-1239.e4.
Title: Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.
Author: Zucman-Rossi, Jessica|Villanueva, Augusto|Nault, Jean-Charles|Llovet, Josep M
PMID: 26099527
Journal: Clin Res Hepatol Gastroenterol. 2015 Sep;39 Suppl 1:S80-5.
Title: New molecular therapies for hepatocellular carcinoma.
Author: Torrecilla, S|Llovet, J M
PMID: 26206572
Journal: Cancer Genet. 2015 Oct;208(10):482-91.
Title: Comparative transcriptome analysis reveals that the extracellular matrix receptor interaction contributes to the venous metastases of hepatocellular carcinoma.
Author: Zhang, Hong|Ye, Junyi|Weng, Xiaoling|Liu, Fatao|He, Lin|Zhou, Daizhan|Liu, Yun
PMID: 26271415
Journal: Nat Genet. 2015 Oct;47(10):1187-93.
Title: Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas.
Author: Nault, Jean-Charles|Datta, Shalini|Imbeaud, Sandrine|Franconi, Andrea|Mallet, Maxime|Couchy, Gabrielle|Letouze, Eric|Pilati, Camilla|Verret, Benjamin|Blanc, Jean-Frederic|Balabaud, Charles|Calderaro, Julien|Laurent, Alexis|Letexier, Melanie|Bioulac-Sage,
PMID: 26301494
Journal: Chem Biol Interact. 2015 Dec 5;242:107-22.
Title: Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells.
Author: Bhullar, Khushwant S|Jha, Amitabh|Rupasinghe, H P Vasantha
PMID: 26409325
Journal: Oncotarget. 2015 Dec 1;6(38):40775-98.
Title: CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc.
Author: Pu, Hu|Zheng, Qidi|Li, Haiyan|Wu, Mengying|An, Jiahui|Gui, Xin|Li, Tianming|Lu, Dongdong
PMID: 26513297
Journal: J Biol Inorg Chem. 2015 Dec;20(8):1287-98.
Title: SOD mimetic activity and antiproliferative properties of a novel tetra nuclear copper (II) complex.
Author: Weintraub, Sagiv|Moskovitz, Yoni|Fleker, Ohad|Levy, Ariel R|Meir, Aviv|Ruthstein, Sharon|Benisvy, Laurent|Gruzman, Arie
PMID: 26547749
Journal: Semin Liver Dis. 2015 Nov;35(4):444-9.
Title: Hepatocellular Carcinoma Arising in an HNF-1alpha-Mutated Adenoma in a 23-Year-Old Woman with Maturity-Onset Diabetes of the Young: A Case Report.
Author: Stueck, Ashley E|Qu, Zhenhong|Huang, Mary Ann Y|Camprecios, Genis|Ferrell, Linda D|Thung, Swan N
PMID: 26676820
Journal: Clin Res Hepatol Gastroenterol. 2016 Feb;40(1):9-14.
Title: TERT promoter mutations in primary liver tumors.
Author: Nault, Jean-Charles|Zucman-Rossi, Jessica
PMID: 26336998
Journal: Transl Res. 2016 Feb;168:122-133.
Title: Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus-related liver carcinogenesis.
Author: Piciocchi, Marika|Cardin, Romilda|Cillo, Umberto|Vitale, Alessandro|Cappon, Andrea|Mescoli, Claudia|Guido, Maria|Rugge, Massimo|Burra, Patrizia|Floreani, Annarosa|Farinati, Fabio
PMID: 26408804
Journal: Tumour Biol. 2016 Mar;37(3):3675-81.
Title: TGF-beta1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells.
Author: Wang, Xin-Hong|Liu, Ming-Na|Sun, Xun|Xu, Chun-Huan|Liu, Jing|Chen, Jing|Xu, Rui-Ling|Li, Bao-Xin
PMID: 26462837
Journal: J Gastroenterol. 2016 May;51(5):473-86.
Title: Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.
Author: Kawai-Kitahata, Fukiko|Asahina, Yasuhiro|Tanaka, Shinji|Kakinuma, Sei|Murakawa, Miyako|Nitta, Sayuri|Watanabe, Takako|Otani, Satoshi|Taniguchi, Miki|Goto, Fumio|Nagata, Hiroko|Kaneko, Shun|Tasaka-Fujita, Megumi|Nishimura-Sakurai, Yuki|Azuma, Seishin|Itsui
PMID: 26553052
Journal: Oncotarget. 2016 Jan 5;7(1):684-99.
Title: The TERT promoter SNP rs2853669 decreases E2F1 transcription factor binding and increases mortality and recurrence risks in liver cancer.
Author: Ko, Eunkyong|Seo, Hyun-Wook|Jung, Eun Sun|Kim, Baek-hui|Jung, Guhung
PMID: 26575952
Journal: Int J Biochem Cell Biol. 2016 Feb;71:1-11.
Title: MiR-103 regulates hepatocellular carcinoma growth by targeting AKAP12.
Author: Xia, Wei|Ni, Jing|Zhuang, Juhua|Qian, Leixing|Wang, Peng|Wang, Jiening
PMID: 26646106
Journal: Oncotarget. 2016 May 3;7(18):25087-102.
Title: Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections.
Author: Tornesello, Maria Lina|Buonaguro, Luigi|Izzo, Francesco|Buonaguro, Franco M
PMID: 26943571
Journal: Hum Pathol. 2016 Jul;53:153-8.
Title: Multiple beta-catenin mutations in hepatocellular lesions arising in Abernethy malformation.
Author: Sorkin, Tracy|Strautnieks, Sandra|Foskett, Pierre|Peddu, Praveen|Thompson, Richard J|Heaton, Nigel|Quaglia, Alberto
PMID: 27038679
Journal: Oncotarget. 2016 May 10;7(19):27838-47.
Title: Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma.
Author: Yang, Xunjun|Guo, Xiuchan|Chen, Yao|Chen, Guorong|Ma, Yin|Huang, Kate|Zhang, Yuning|Zhao, Qiongya|Winkler, Cheryl A|An, Ping|Lyu, Jianxin
PMID: 27056898
Journal: Eur J Pharm Sci. 2016 Jun 10;88:274-81.
Title: Novel fluorinated docetaxel analog for anti-hepatoma: Molecular docking and biological evaluation.
Author: Hao, Yun-Peng|Liu, Zheng-Yu|Xie, Cheng|Zhou, Lu|Sun, Xun
PMID: 27058438
Journal: Nat Genet. 2016 May;48(5):500-9.
Title: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.
Author: Fujimoto, Akihiro|Furuta, Mayuko|Totoki, Yasushi|Tsunoda, Tatsuhiko|Kato, Mamoru|Shiraishi, Yuichi|Tanaka, Hiroko|Taniguchi, Hiroaki|Kawakami, Yoshiiku|Ueno, Masaki|Gotoh, Kunihito|Ariizumi, Shun-Ichi|Wardell, Christopher P|Hayami, Shinya|Nakamura, Toru|A
PMID: 27064257
Journal: Oncotarget. 2016 Oct 11;7(41):66525-66539.
Title: Double mutant P53 (N340Q/L344R) promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDR.
Author: Wu, Mengying|An, Jiahui|Zheng, Qidi|Xin, Xiaoru|Lin, Zhuojia|Li, Xiaonan|Li, Haiyan|Lu, Dongdong
PMID: 27167190
Journal: Oncotarget. 2016 Jun 28;7(26):40481-40490.
Title: Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing.
Author: Liao, Wenjun|Yang, Huayu|Xu, Haifeng|Wang, Yanan|Ge, Penglei|Ren, Jinjun|Xu, Wei|Lu, Xin|Sang, Xinting|Zhong, Shouxian|Zhang, Hongbing|Mao, Yilei
PMID: 27248174
Journal: J BUON. 2016 Mar-Apr;21(2):491-7.
Title: New evidence of TERT rs2736098 polymorphism and cancer risk: an updated meta-analysis.
Author: Li, Tong|Xian, Yun|Tian, Tian|Zhuang, Xun|Chu, Minjie
PMID: 27273963
Journal: Oncotarget. 2016 Aug 23;7(34):54253-54262.
Title: Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma.
Author: Pezzuto, Francesca|Izzo, Francesco|Buonaguro, Luigi|Annunziata, Clorinda|Tatangelo, Fabiana|Botti, Gerardo|Buonaguro, Franco M|Tornesello, Maria Lina
PMID: 27276713
Journal: Mol Cell Oncol. 2016 Jan 19;3(2):e1095271.
Title: Adeno-associated virus type 2 as an oncogenic virus in human hepatocellular carcinoma.
Author: Nault, Jean-Charles|Datta, Shalini|Imbeaud, Sandrine|Franconi, Andrea|Zucman-Rossi, Jessica
PMID: 27308626
Journal: Oncotarget. 2016 Aug 2;7(31):50131-50149.
Title: Inflammatory related gene IKKalpha, IKKbeta, IKKgamma cooperates to determine liver cancer stem cells progression by altering telomere via heterochromatin protein 1-HOTAIR axis.
Author: An, Jiahui|Wu, Mengying|Xin, Xiaoru|Lin, Zhuojia|Li, Xiaonan|Zheng, Qidi|Gui, Xin|Li, Tianming|Pu, Hu|Li, Haiyan|Lu, Dongdong
PMID: 27367027
Journal: Biomed Res Int. 2016;2016:6186281.
Title: Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks.
Author: Lin, Shengda|Yin, Yi A|Jiang, Xiaoqian|Sahni, Nidhi|Yi, Song
PMID: 27403431
Journal: Int J Cancer. 2016 Dec 1;139(11):2512-8.
Title: TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma.
Author: Ki Kim, Soo|Ueda, Yoshihide|Hatano, Etsuro|Kakiuchi, Nobuyuki|Takeda, Haruhiko|Goto, Tomoyuki|Shimizu, Takahiro|Yoshida, Kenichi|Ikura, Yoshihiro|Shiraishi, Yuichi|Chiba, Kenichi|Tanaka, Hiroko|Miyano, Satoru|Uemoto, Shinji|Chiba, Tsutomu|Ogawa, Seishi|Ma
PMID: 27511114
Journal: J Gastrointest Oncol. 2016 Aug;7(4):570-9.
Title: A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma.
Author: Mok, Shaffer R S|Mohan, Sachin|Grewal, Navjot|Elfant, Adam B|Judge, Thomas A
PMID: 27563447
Journal: J Clin Invest. 2016 Oct 3;126(10):4045-4060.
Title: Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression.
Author: Khattar, Ekta|Kumar, Pavanish|Liu, Chia Yi|Akincilar, Semih Can|Raju, Anandhkumar|Lakshmanan, Manikandan|Maury, Julien Jean Pierre|Qiang, Yu|Li, Shang|Tan, Ern Yu|Hui, Kam M|Shi, Ming|Loh, Yuin Han|Tergaonkar, Vinay
PMID: 27643433
Journal: Oncotarget. 2016 Oct 25;7(43):69267-69275.
Title: Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma.
Author: Lee, Seung Eun|Chang, Seong-Hwan|Kim, Wook Youn|Lim, So Dug|Kim, Wan Seop|Hwang, Tea Sook|Han, Hye Seung
PMID: 27661004
Journal: J Cancer. 2016 Sep 13;7(13):1907-1914.
Title: Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity.
Author: Huang, Ao|Zhang, Xin|Zhou, Shao-Lai|Cao, Ya|Huang, Xiao-Wu|Fan, Jia|Yang, Xin-Rong|Zhou, Jian
PMID: 27698932
Journal: Zhonghua Gan Zang Bing Za Zhi. 2016 Jul 20;24(7):555-560.
Title: [Studies on telomerase reverse transcriptase components and liver cancer].
Author: Cai, J J|Guo, X L
PMID: 27784441
Journal: PLoS One. 2016 Nov 2;11(11):e0165457.
Title: Integrated Multiple "-omics" Data Reveal Subtypes of Hepatocellular Carcinoma.
Author: Liu, Gang|Dong, Chuanpeng|Liu, Lei
PMID: 27806083
Journal: J Phys Chem A. 2016 Dec 15;120(49):9829-9840.
Title: Envisaging Structural Insight of a Terminally Protected Proline Dipeptide by Raman Spectroscopy and Density Functional Theory Analyses.
Author: Das, Supriya|Pal, Uttam|Chatterjee, Moumita|Pramanik, Sumit Kumar|Banerji, Biswadip|Maiti, Nakul C
PMID: 27973793
Journal: Histopathology. 2017 Feb;70(3):423-434.
Title: Mutational landscape of combined hepatocellular carcinoma and cholangiocarcinoma, and its clinicopathological significance.
Author: Sasaki, Motoko|Sato, Yasunori|Nakanuma, Yasuni
PMID: 27634656
Journal: Gastroenterology. 2017 Mar;152(4):880-894.e6.
Title: Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.
Author: Nault, Jean-Charles|Couchy, Gabrielle|Balabaud, Charles|Morcrette, Guillaume|Caruso, Stefano|Blanc, Jean-Frederic|Bacq, Yannick|Calderaro, Julien|Paradis, Valerie|Ramos, Jeanne|Scoazec, Jean-Yves|Gnemmi, Viviane|Sturm, Nathalie|Guettier, Catherine|Fabre,
PMID: 27939373
Journal: Hum Pathol. 2017 Apr;62:122-125.
Title: Malignant transformation of a beta-catenin inflammatory adenoma due to an S45 beta-catenin-activating mutation present 12 years before.
Author: Sempoux, Christine|Bisig, Bettina|Couchy, Gabrielle|Balabaud, Charles|Zucman-Rossi, Jessica|Bioulac-Sage, Paulette
PMID: 27984126
Journal: Medicine (Baltimore). 2017 Feb;96(5):e5766.
Title: Clinicopathological characteristics of TERT promoter mutation and telomere length in hepatocellular carcinoma.
Author: Lee, Hye Won|Park, Tae In|Jang, Se Young|Park, Soo Young|Park, Won-Jin|Jung, Soo-Jung|Lee, Jae-Ho
PMID: 28151853
Journal: J Mol Med (Berl). 2017 Jun;95(6):629-639.
Title: HCV core inhibits hepatocellular carcinoma cell replicative senescence through downregulating microRNA-138 expression.
Author: Shiu, Tzu-Yue|Shih, Yu-Lueng|Feng, An-Chieh|Lin, Hsuan-Hwai|Huang, Shih-Ming|Huang, Tien-Yu|Hsieh, Chung-Bao|Chang, Wei-Kuo|Hsieh, Tsai-Yuan
PMID: 28258280
Journal: J Egypt Natl Canc Inst. 2017 Mar;29(1):19-24.
Title: Gene expression profiling of circulating CD133(+) cells of hepatocellular carcinoma patients associated with HCV infection.
Author: Zekri, Abdel-Rahman N|El-Sisi, Enas R|Abdallah, Zeinab F|Ismail, Alaa|Barakat Barakat, Ahmed
PMID: 28258914
Journal: Liver Int. 2017 Nov;37(11):1591-1601.
Title: Constitutional and functional genetics of human alcohol-related hepatocellular carcinoma.
Author: Nahon, Pierre|Nault, Jean-Charles
PMID: 28296015
Journal: Cancer Res. 2017 May 1;77(9):2255-2265.
Title: Genomic and Epigenomic Heterogeneity of Hepatocellular Carcinoma.
Author: Lin, De-Chen|Mayakonda, Anand|Dinh, Huy Q|Huang, Pinbo|Lin, Lehang|Liu, Xiaoping|Ding, Ling-Wen|Wang, Jie|Berman, Benjamin P|Song, Er-Wei|Yin, Dong|Koeffler, H Phillip
PMID: 28302680
Journal: Mutat Res. 2017 Jan - Mar;771:15-31.
Title: TERT promoter mutations in telomere biology.
Author: Heidenreich, Barbara|Kumar, Rajiv
PMID: 28342451
Journal: BMC Bioinformatics. 2017 Mar 14;18(Suppl 3):71.
Title: BATVI: Fast, sensitive and accurate detection of virus integrations.
Author: Tennakoon, Chandana|Sung, Wing Kin
PMID: 28361674
Journal: Oncol Rep. 2017 May;37(5):3037-3045.
Title: Recombinant adenovirus of SEA and CD80 genes driven by MMRE and mouse TERT promoter induce effective antitumor immune responses against different types of tumor cells in vitro and in vivo.
Author: Si, Shao-Yan|Liu, Jun-Li|Liu, Jun-Lian|Xu, Bing-Xin|Li, Jian-Zhong|Qin, Ya-Ya|Song, Shu-Jun
PMID: 28393253
Journal: Oncotarget. 2017 Apr 18;8(16):26288-26297.
Title: Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma.
Author: Huang, Wan|Zhou, Weiping|Li, Can|Yang, Yuan|Shang, Yu-Kui|Chen, Changsheng|Zhang, Jing|Yao, Rui|Wang, Pei|Wen, Wen|Liu, Han-Qiang|Wang, Ling|Li, Xia|Bian, Huijie|Chen, Zhi-Nan
PMID: 28460432
Journal: Infect Agent Cancer. 2017 May 19;12:27.
Title: Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma.
Author: Pezzuto, Francesca|Buonaguro, Luigi|Buonaguro, Franco M|Tornesello, Maria Lina
PMID: 28529542
Journal: J Hepatol. 2017 Oct;67(4):727-738.
Title: Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.
Author: Calderaro, Julien|Couchy, Gabrielle|Imbeaud, Sandrine|Amaddeo, Giuliana|Letouze, Eric|Blanc, Jean-Frederic|Laurent, Christophe|Hajji, Yacine|Azoulay, Daniel|Bioulac-Sage, Paulette|Nault, Jean-Charles|Zucman-Rossi, Jessica
PMID: 28532995
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: Cell. 2017 Jun 15;169(7):1327-1341.e23.
Title: Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.
Author:
PMID: 28622513
Journal: PLoS One. 2017 Aug 16;12(8):e0183287.
Title: Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma.
Author: Donaires, Flavia S|Scatena, Natalia F|Alves-Paiva, Raquel M|Podlevsky, Joshua D|Logeswaran, Dhenugen|Santana, Barbara A|Teixeira, Andreza C|Chen, Julian J-L|Calado, Rodrigo T|Martinelli, Ana L C
PMID: 28813500
Journal: Rapid Commun Mass Spectrom. 2017 Nov 15;31(21):1851-1858.
Title: Quantification of six potential unspecific human biomarkers of 1-vinyl-2-pyrrolidone exposure in Sprague-Dawley rat urine using gas chromatography coupled with triple mass spectrometry.
Author: Bertram, J|Schettgen, T|Kraus, T
PMID: 28841759
Journal: J Hepatol. 2017 Dec;67(6):1222-1231.
Title: Trunk mutational events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma.
Author: Torrecilla, Sara|Sia, Daniela|Harrington, Andrew N|Zhang, Zhongyang|Cabellos, Laia|Cornella, Helena|Moeini, Agrin|Camprecios, Genis|Leow, Wei-Qiang|Fiel, Maria Isabel|Hao, Ke|Bassaganyas, Laia|Mahajan, Milind|Thung, Swan N|Villanueva, Augusto|Florman, San
PMID: 28843658
Journal: Mol Cancer. 2017 Aug 30;16(1):149.
Title: The biology of Hepatocellular carcinoma: implications for genomic and immune therapies.
Author: Khemlina, Galina|Ikeda, Sadakatsu|Kurzrock, Razelle
PMID: 28854942
Journal: Sci Rep. 2017 Sep 25;7(1):12258.
Title: Clinical importance of TERT overexpression in hepatocellular carcinoma treated with curative surgical resection in HBV endemic area.
Author: Yu, Jeong Il|Choi, Changhoon|Ha, Sang Yun|Park, Cheol-Keun|Kang, So Young|Joh, Jae-Won|Paik, Seung Woon|Kim, Seonwoo|Kim, Minji|Jung, Sang Hoon|Park, Hee Chul
PMID: 28947783
Journal: Oncotarget. 2017 Jun 29;8(38):63620-63634.
Title: A validated, transitional and translational porcine model of hepatocellular carcinoma.
Author: Schachtschneider, Kyle M|Schwind, Regina M|Darfour-Oduro, Kwame A|De, Arun K|Rund, Lauretta A|Singh, Kuldeep|Principe, Daniel R|Guzman, Grace|Ray, Charles E Jr|Ozer, Howard|Gaba, Ron C|Schook, Lawrence B
PMID: 28969016
Journal: Onco Targets Ther. 2017 Oct 3;10:4853-4858.
Title: TERT-CLPTM1 locus polymorphism (rs401681) is associated with the prognosis of hepatocellular carcinoma.
Author: Lee, Hye Won|Park, Won-Jin|Heo, Yu-Ran|Park, Tae In|Park, Soo Young|Lee, Jae-Ho
PMID: 29042796
Journal: Hum Pathol. 2018 Feb;72:127-134.
Title: Distinction of intrahepatic metastasis from multicentric carcinogenesis in multifocal hepatocellular carcinoma using molecular alterations.
Author: Chianchiano, Peter|Pezhouh, Maryam Kherad|Kim, Amy|Luchini, Claudio|Cameron, Andrew|Weiss, Matthew J|He, Jin|Voltaggio, Lysandra|Oshima, Kiyoko|Anders, Robert A|Wood, Laura D
PMID: 29180252
Journal: NPJ Genom Med. 2018 Jan 11;3:1.
Title: Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival.
Author: Hornshoj, Henrik|Nielsen, Morten Muhlig|Sinnott-Armstrong, Nicholas A|Switnicki, Michal P|Juul, Malene|Madsen, Tobias|Sallari, Richard|Kellis, Manolis|Orntoft, Torben|Hobolth, Asger|Pedersen, Jakob Skou
PMID: 29354286
Journal: Future Oncol. 2018 Mar;14(6):553-566.
Title: Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma.
Author: DeLeon, Thomas T|Ahn, Daniel H|Bogenberger, James M|Anastasiadis, Panos Z|Arora, Mansi|Ramanathan, Ramesh K|Aqel, Bashar A|Vasmatzis, George|Truty, Mark J|Oklu, Rahmi|Bekaii-Saab, Tanios S|Borad, Mitesh J
PMID: 29460642
Journal: Theranostics. 2018 Feb 12;8(6):1740-1751.
Title: Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features.
Author: Li, Xiangchun|Xu, Weiqi|Kang, Wei|Wong, Sunny H|Wang, Mengyao|Zhou, Yong|Fang, Xiaodong|Zhang, Xiuqing|Yang, Huanming|Wong, Chi H|To, Ka F|Chan, Stephen L|Chan, Matthew T V|Sung, Joseph J Y|Wu, William K K|Yu, Jun
PMID: 29556353
Journal: Cancer Sci. 2018 May;109(5):1282-1291.
Title: Molecular genomic landscapes of hepatobiliary cancer.
Author: Shibata, Tatsuhiro|Arai, Yasuhito|Totoki, Yasushi
PMID: 29573058
Journal: J Cell Mol Med. 2018 Jun;22(6):3246-3258.
Title: Inflammatory factor receptor Toll-like receptor 4 controls telomeres through heterochromatin protein 1 isoforms in liver cancer stem cell.
Author: Zheng, Qidi|Xu, Jie|Lin, Zhuojia|Lu, Yanan|Xin, Xiaoru|Li, Xiaonan|Yang, Yuxin|Meng, Qiuyu|Wang, Chen|Xiong, Wujun|Lu, Dongdong
PMID: 29602239
Journal: Oncogene. 2018 Jul;37(27):3740-3752.
Title: A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.
Author: Labgaa, Ismail|Villacorta-Martin, Carlos|D'Avola, Delia|Craig, Amanda J|von Felden, Johann|Martins-Filho, Sebastiao N|Sia, Daniela|Stueck, Ashley|Ward, Stephen C|Fiel, M Isabel|Mahajan, Milind|Tabrizian, Parissa|Thung, Swan N|Ang, Celina|Friedman, Scott L
PMID: 29628508
Journal: IUBMB Life. 2018 Jul;70(7):642-648.
Title: Telomerase reverse transcriptase suppression inhibits cell proliferation and promotes cell apoptosis in hepatocellular cancer.
Author: Shen, Yanfeng|Xi, Feng|Li, Haibin|Luo, Yin|Chen, Cheng|Wang, Lei
PMID: 29707886
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: Histopathology. 2018 Oct;73(4):601-611.
Title: Phenotypic and molecular changes in nodule-in-nodule hepatocellular carcinoma with pathogenetic implications.
Author: Rudini, Noemi|Novello, Chiara|Destro, Annarita|Riboldi, Elena|Donadon, Matteo|Vigano, Luca|Morenghi, Emanuela|Roncalli, Massimo|Di Tommaso, Luca
PMID: 29791027
Journal: Oncotarget. 2018 May 18;9(38):25075-25088.
Title: Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers.
Author: Furuta, Mayuko|Tanaka, Hiroko|Shiraishi, Yuichi|Unida, Takuro|Imamura, Michio|Fujimoto, Akihiro|Fujita, Masahi|Sasaki-Oku, Aya|Maejima, Kazuhiro|Nakano, Kaoru|Kawakami, Yoshiiku|Arihiro, Koji|Aikata, Hiroshi|Ueno, Masaki|Hayami, Shinya|Ariizumi, Shun-Ichi
PMID: 29861854
Journal: Acta Crystallogr C Struct Chem. 2018 Jun 1;74(Pt 6):659-665.
Title: Novel asymmetric 3,5-bis(arylidene)piperidin-4-one derivatives: synthesis, crystal structures and cytotoxicity.
Author: Yao, Binrong|Li, Ning|Wang, Chunhua|Hou, Guige|Meng, Qingguo|Yan, Ke
PMID: 29870000
Journal: Hepatol Commun. 2018 Apr 27;2(6):718-731.
Title: Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors.
Author: Jiao, Jingjing|Watt, Gordon P|Stevenson, Heather L|Calderone, Tiffany L|Fisher-Hoch, Susan P|Ye, Yuanqing|Wu, Xifeng|Vierling, John M|Beretta, Laura
PMID: 29881823
Journal: Sensors (Basel). 2018 Jun 26;18(7). pii: s18072042.
Title: Coumarin Probe for Selective Detection of Fluoride Ions in Aqueous Solution and Its Bioimaging in Live Cells.
Author: Chansaenpak, Kantapat|Kamkaew, Anyanee|Weeranantanapan, Oratai|Suttisintong, Khomson|Tumcharern, Gamolwan
PMID: 29949921
Journal: Clin Cancer Res. 2018 Jun 27. pii: 1078-0432.CCR-17-3588.
Title: Phase II Studies with Refametinib or Refametinib plus Sorafenib in Patients with RAS-Mutated Hepatocellular Carcinoma.
Author: Lim, Ho Yeong|Merle, Philippe|Weiss, Karl Heinz|Yau, Thomas|Ross, Paul|Mazzaferro, Vincenzo|Blanc, Jean-Frederic|Ma, Yuk Ting|Yen, Chia Jui|Kocsis, Judit|Choo, Su Pin|Sukeepaisarnjaroen, Wattana|Gerolami, Rene|Dufour, Jean-Francois|Gane, Edward J|Ryoo, Ba
PMID: 29950351
Journal: Int J Cancer. 2018 Jul 10.
Title: Suppression of PROX1-mediated TERT expression in hepatitis B viral hepatocellular carcinoma.
Author: Kim, Young-Joo|Yoo, Jeong Eun|Jeon, Youngsic|Chong, Jae Uk|Choi, Gi Hong|Song, Dae-Geun|Jung, Sang Hoon|Oh, Bong-Kyeong|Park, Young Nyun
PMID: 29987895
Journal: Cancer Lett. 2018 Oct 10;434:33-41.
Title: Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma.
Author: Yu, Jingya|Yuan, Xiaotian|Sjoholm, Louise|Liu, Tiantian|Kong, Feng|Ekstrom, Tomas J|Bjorkholm, Magnus|Xu, Dawei
PMID: 30017965
Journal: Hepatology. 2018 Aug 2.
Title: Androgen Receptor Enhances Hepatic TERT Transcription after Hepatitis B Virus Integration or Point Mutation in Promoter Region.
Author: Li, Chiao-Ling|Li, Chen-Yu|Lin, You-Yu|Ho, Ming-Chih|Chen, Ding-Shinn|Yeh, Shiou-Hwei|Chen, Pei-Jer
PMID: 30070724
Journal: Front Genet. 2018 Jul 19;9:261.
Title: Host and Viral Genetic Variation in HBV-Related Hepatocellular Carcinoma.
Author: An, Ping|Xu, Jinghang|Yu, Yanyan|Winkler, Cheryl A
PMID: 30073017
Journal: Biol Rev Camb Philos Soc. 2018 Aug 13.
Title: Comprehensive review of Hepatitis B Virus-associated hepatocellular carcinoma research through text mining and big data analytics.
Author: Lee, Wai Yeow|Bachtiar, Maulana|Choo, Cheryl C S|Lee, Caroline G
PMID: 30105774
Journal: J Mol Diagn. 2018 Aug 22. pii: S1525-1578(18)30025-4.
Title: Diagnostic Targeted Sequencing Panel for Hepatocellular Carcinoma Genomic Screening.
Author: Paradiso, Viola|Garofoli, Andrea|Tosti, Nadia|Lanzafame, Manuela|Perrina, Valeria|Quagliata, Luca|Matter, Matthias S|Wieland, Stefan|Heim, Markus H|Piscuoglio, Salvatore|Ng, Charlotte K Y|Terracciano, Luigi M
PMID: 30142445
Journal: Int J Cancer. 2018 Sep 24.
Title: Analysis of The Cancer Genome Atlas data to determine the correlation between PROX1 and TERT in hepatocellular carcinoma.
Author: Lee, Jae-Ho
PMID: 30246869
Journal: Cancers (Basel). 2018 Sep 29;10(10). pii: cancers10100367.
Title: Molecular Scoring of Hepatocellular Carcinoma for Predicting Metastatic Recurrence and Requirements of Systemic Chemotherapy.
Author: Nishida, Naoshi|Nishimura, Takafumi|Kaido, Toshimi|Minaga, Kosuke|Yamao, Kentaro|Kamata, Ken|Takenaka, Mamoru|Ida, Hiroshi|Hagiwara, Satoru|Minami, Yasunori|Sakurai, Toshiharu|Watanabe, Tomohiro|Kudo, Masatoshi
PMID: 30274313