Primary Site >> Colorectal Cancer

Gene >> TERT

1.
Journal: J Med Chem. 1994 May 27;37(11):1616-24.
Title: Synthesis and antitumor activities of novel 6-5 fused ring heterocycle antifolates: N-[4-[omega-(2-amino-4-substituted-6,7-dihydrocyclopenta [d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic acids.
Author: Kotake, Y|Iijima, A|Yoshimatsu, K|Tamai, N|Ozawa, Y|Koyanagi, N|Kitoh, K|Nomura, H
PMID: 8201595
2.
Journal: Biochem Pharmacol. 1995 Mar 1;49(5):669-75.
Title: Phenolic antioxidant-induced overexpression of class-3 aldehyde dehydrogenase and oxazaphosphorine-specific resistance.
Author: Sreerama, L|Rekha, G K|Sladek, N E
PMID: 7887982
3.
Journal: Drug Metab Dispos. 1996 Jun;24(6):655-8.
Title: Isolation, purification and biological activity of major docetaxel metabolites from human feces.
Author: Sparreboom, A|Van Tellingen, O|Scherrenburg, E J|Boesen, J J|Huizing, M T|Nooijen, W J|Versluis, C|Beijnen, J H
PMID: 8781781
4.
Journal: Oncogene. 1999 Feb 25;18(8):1561-7.
Title: Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections.
Author: Tahara, H|Yasui, W|Tahara, E|Fujimoto, J|Ito, K|Tamai, K|Nakayama, J|Ishikawa, F|Tahara, E|Ide, T
PMID: 10102626
5.
Journal: Zhonghua Bing Li Xue Za Zhi. 2000 Feb;29(1):16-9.
Title: [Expression of telomerase genes in human tumors].
Author: Yuan, X|Zhang, B|Ying, J|Jin, Y|Hou, L
PMID: 11866885
6.
Journal: Cell Growth Differ. 2001 Feb;12(2):119-27.
Title: Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells.
Author: Yang, H|Kyo, S|Takatura, M|Sun, L
PMID: 11243466
7.
Journal: Am J Gastroenterol. 2001 Jun;96(6):1895-900.
Title: Quantitative analysis of hTERT mRNA expression in colorectal cancer.
Author: Niiyama, H|Mizumoto, K|Sato, N|Nagai, E|Mibu, R|Fukui, T|Kinoshita, M|Tanaka, M
PMID: 11419845
8.
Journal: Oncogene. 2001 May 3;20(20):2600-5.
Title: Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas.
Author: Szutorisz, H|Palmqvist, R|Roos, G|Stenling, R|Schorderet, D F|Reddel, R|Lingner, J|Nabholz, M
PMID: 11420670
9.
Journal: Eur J Med Chem. 2001 Apr;36(4):321-32.
Title: Pyrazolopyrimidines: synthesis, effect on histamine release from rat peritoneal mast cells and cytotoxic activity.
Author: Quintela, J M|Peinador, C|Moreira, M J|Alfonso, A|Botana, L M|Riguera, R
PMID: 11461757
10.
Journal: BMC Cancer. 2001;1:10. Epub 2001 Aug 1.
Title: Long-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: an in vitro study.
Author: Kuranaga, N|Shinomiya, N|Mochizuki, H
PMID: 11518543
11.
Journal: Tumour Biol. 2001 Nov-Dec;22(6):374-82.
Title: Telomerase activity and expression of telomerase RNA component and catalytic subunits in precancerous and cancerous colorectal lesions.
Author: Naito, Y|Takagi, T|Handa, O|Ishikawa, T|Matsumoto, N|Yoshida, N|Kato, H|Ando, T|Takemura, T|Itani, K|Hisatomi, H|Tsuchihashi, Y|Yoshikawa, T
PMID: 11786731
12.
Journal: Oncogene. 2002 Jan 21;21(4):643-9.
Title: Clinical utility of telomerase in cancer.
Author: Hiyama, Eiso|Hiyama, Keiko
PMID: 11850791
13.
Journal: Jpn J Clin Oncol. 2002 Jan;32(1):3-8.
Title: Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP.
Author: Nomoto, Kiyoaki|Maekawa, Masato|Sugano, Kokichi|Ushiama, Mineko|Fukayama, Noriko|Fujita, Shin|Kakizoe, Tadao
PMID: 11932355
14.
Journal: Int J Mol Med. 2002 Aug;10(2):205-10.
Title: Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer.
Author: Kanamaru, Taichi|Tanaka, Ken-Ichi|Kotani, Joji|Ueno, Kimihiko|Yamamoto, Masahiro|Idei, Yuka|Hisatomi, Hisashi|Takeyama, Yoshifumi
PMID: 12119560
15.
Journal: Int J Oncol. 2002 Sep;21(3):493-7.
Title: Evaluation of telomerase mRNA (hTERT) in colon cancer.
Author: Boldrini, L|Faviana, P|Gisfredi, S|Zucconi, Y|Di Quirico, D|Donati, V|Berti, P|Spisni, R|Galleri, D|Materazzi, G|Basolo, F|Miccoli, P|Pingitore, R|Fontanini, G
PMID: 12168091
16.
Journal: Int J Oncol. 2002 Sep;21(3):661-6.
Title: Cancer-specific killing by the CD suicide gene using the human telomerase reverse transcriptase promoter.
Author: Liu, Jing|Zou, Wei-Guo|Lang, Ming-Fei|Luo, Jia|Sun, Lan-Ying|Wang, Xiao-Ning|Qian, Qi-Jun|Liu, Xin-Yuan
PMID: 12168115
17.
Journal: Hum Pathol. 2002 Jul;33(7):693-6.
Title: Immunohistochemical detection of telomerase reverse transcriptase in colorectal adenocarcinoma and benign colonic mucosa.
Author: Wei, Randy|Younes, Mamoun
PMID: 12196919
18.
Journal: Cancer. 2002 Nov 15;95(10):2103-11.
Title: Prognostic potential of the telomerase subunit human telomerase reverse transcriptase in tumor tissue and nontumorous mucosa from patients with colorectal carcinoma.
Author: Gertler, Ralf|Rosenberg, Robert|Stricker, Dominik|Werner, Martin|Lassmann, Silke|Ulm, Kurt|Nekarda, Hjalmar|Siewert, Joerg-Ruediger
PMID: 12412163
19.
Journal: Eur J Gastroenterol Hepatol. 2003 Jan;15(1):75-80.
Title: Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients.
Author: Nowak, Jerzy|Januszkiewicz, Danuta|Lewandowski, Krzysztof|Nowicka-Kujawska, Karina|Pernak, Monika|Rembowska, Jolanta|Nowak, Tomasz|Wysocki, Jacek
PMID: 12544698
20.
Journal: Recent Results Cancer Res. 2003;162:177-81.
Title: Telomere length and hTERT expression in patients with colorectal carcinoma.
Author: Rosenberg, Robert|Gertler, Ralf|Stricker, Dominik|Lassmann, Silke|Werner, Martin|Nekarda, Hjalmar|Siewert, Joerg Ruediger
PMID: 12790332
21.
Journal: Anticancer Res. 2003 Mar-Apr;23(2B):1605-12.
Title: Changes in telomerase activity, expression and splicing in response to differentiation of normal and carcinoma colon cells.
Author: Fajkus, Jiri|Borsky, Marek|Kunicka, Zuzana|Kovarikova, Martina|Dvorakova, Dana|Hofmanova, Jirina|Kozubik, Alois
PMID: 12820429
22.
Journal: World J Gastroenterol. 2003 Sep;9(9):1981-4.
Title: Telomerase activity and cell apoptosis in colon cancer cell by human telomerase reverse transcriptase gene antisense oligodeoxynucleotide.
Author: Jiang, Ying-An|Luo, He-Sheng|Zhang, You-Yuan|Fan, Li-Fang|Jiang, Chong-Qing|Chen, Wei-Jin
PMID: 12970889
23.
Journal: Anticancer Res. 2003 Nov-Dec;23(6C):4821-9.
Title: Development of a highly sensitive RT-PCR luminometric hybridization assay for human telomerase reverse-transcriptase beta-plus transcript.
Author: Angelopoulou, Katerina|Spiropoulou, Tonia|Stathopoulou, Aliki|Dimitroulopoulos, Dimitris|Malamos, Nikos|Georgoulias, Vassilis|Paraskevas, Emanouil|Lianidou, Evi S
PMID: 14981931
24.
Journal: Oncol Rep. 2004 Jan;11(1):127-31.
Title: Differential alternative splicing expressions of telomerase reverse transcriptase in gastrointestinal cell lines.
Author: Nagao, Kumi|Katsumata, Kenji|Aizawa, Yoshio|Saito, Noboru|Hirata, Hiroyuki|Sasaki, Hiroshi|Yamamoto, Shigeki|Hikiji, Kazumasa|Koiwa, Tsukasa|Hisatomi, Hisashi
PMID: 14654914
25.
Journal: Oncol Rep. 2004 Feb;11(2):395-400.
Title: Regulation of telomerase and its hTERT messenger in colorectal cancer.
Author: Boldrini, Laura|Faviana, Pinuccia|Gisfredi, Silvia|Donati, Valentina|Zucconi, Ylenia|Ursino, Silvia|Simi, Paolo|Baldinotti, Fulvia|Berti, Piero|Galleri, Davide|Materazzi, Gabriele|Basolo, Fulvio|Miccoli, Paolo|Pingitore, Raffaele|Fontanini, Gabriella
PMID: 14719074
26.
Journal: J Clin Oncol. 2004 May 15;22(10):1807-14.
Title: Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma.
Author: Gertler, Ralf|Rosenberg, Robert|Stricker, Dominik|Friederichs, Jan|Hoos, Axel|Werner, Martin|Ulm, Kurt|Holzmann, Bernhard|Nekarda, Hjalmar|Siewert, Joerg-Ruediger
PMID: 15143073
27.
Journal: Clin Cancer Res. 2004 May 15;10(10):3535-41.
Title: Suppressing orthotopic pancreatic tumor growth with a fiber-modified adenovector expressing the TRAIL gene from the human telomerase reverse transcriptase promoter.
Author: Jacob, Dietmar|Davis, John|Zhu, Hongbo|Zhang, Lidong|Teraishi, Fuminori|Wu, Shuhong|Marini, Frank C 3rd|Fang, Bingliang
PMID: 15161713
28.
Journal: Neoplasma. 2004;51(2):90-6.
Title: Telomerase as a diagnostic and predictive marker in colorectal carcinoma.
Author: Malaska, J|Kunicka, Z|Borsky, M|Sklenickova, M|Novotna, M|Fajkusova, L|Zaloudik, J|Fajkus, J
PMID: 15190417
29.
Journal: Toxicol Pathol. 2004 Mar-Apr;32(2):250-7.
Title: Modifying effects of 1'-acetoxychavicol acetate (ACA) and the novel synthetic retinoids Re-80, Am-580 and Am-55P in a two-stage carcinogenesis model in female rats.
Author: Orita, Shinichiro|Hirose, Masao|Takahashi, Satoru|Imaida, Katsumi|Ito, Nobuyuki|Shudo, Koichi|Ohigashi, Hajime|Murakami, Akira|Shirai, Tomoyuki
PMID: 15200164
30.
Journal: Colorectal Dis. 2004 Jul;6(4):236-42.
Title: Real time quantification in plasma of human telomerase reverse transcriptase (hTERT) mRNA in patients with colorectal cancer.
Author: Lledo, S M|Garcia-Granero, E|Dasi, F|Ripoli, R|Garcia, S A|Cervantes, A|Alino, S F
PMID: 15206965
31.
Journal: Biol Chem. 2004 Jun;385(6):449-64.
Title: Colon cancer: genomics and apoptotic events.
Author: Rupnarain, Charleen|Dlamini, Zodwa|Naicker, Sarala|Bhoola, Kanti
PMID: 15255176
32.
Journal: Invest New Drugs. 2004 Nov;22(4):369-78.
Title: Antineoplastic potency of arylchloroethylurea derivatives in murine colon carcinoma.
Author: Miot-Noirault, Elisabeth|Legault, Jean|Cachin, Florent|Mounetou, Emmanuelle|Degoul, Francoise|Gaudreault, Rene C|Moins, Nicole|Madelmont, Jean Claude
PMID: 15292707
33.
Journal: Oncol Rep. 2004 Oct;12(4):871-6.
Title: Cytotoxic T-cell immunity against telomerase reverse transcriptase in colorectal cancer patients.
Author: Titu, Liviu V|Loveday, Ruth L|Madden, Leigh A|Cawkwell, Lynn|Monson, John R|Greenman, John
PMID: 15375515
34.
Journal: Int J Oncol. 2004 Oct;25(4):1049-56.
Title: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR.
Author: Solmi, Rossella|De Sanctis, Paola|Zucchini, Cinzia|Ugolini, Giampaolo|Rosati, Giancarlo|Del Governatore, Marco|Coppola, Domenico|Yeatman, Thymothy J|Lenzi, Luca|Caira, Antonello|Zanotti, Simone|Taffurelli, Mario|Carinci, Paolo|Valvassori, Luisa|Strippoli,
PMID: 15375555
35.
Journal: Dig Dis Sci. 2004 Sep;49(9):1504-12.
Title: Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation.
Author: Nakamura, Atsuo|Suda, Takeshi|Honma, Terasu|Takahashi, Toru|Igarashi, Masato|Waguri, Nobuo|Kawai, Hirokazu|Mita, Yusaku|Aoyagi, Yutaka
PMID: 15481329
36.
Journal: Anticancer Res. 2004 Sep-Oct;24(5A):3075-9.
Title: Gene therapy in colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter.
Author: Jacob, Dietmar|Bahra, Marcus|Schumacher, Guido|Neuhaus, Peter|Fang, Bingliang
PMID: 15517918
37.
Journal: Ai Zheng. 2004 Nov;23(11 Suppl):1502-7.
Title: [Clinical significance of human telomerase reverse transcriptase in patients with colon cancer].
Author: Li, Li-Ren|Wan, De-Sen|Pan, Zhi-Zhong|Hardingham, Jenny|Rieger, Nick|Hewett, Peter|Zhou, Zhi-Wei|Chen, Gong
PMID: 15566667
38.
Journal: Z Gastroenterol. 2004 Dec;42(12):1363-70.
Title: [Adenoviral vector expressing the TRAIL gene driven by the hTERT promoter].
Author: Jacob, D|Davis, J|Schumacher, G|Bahra, M|Neuhaus, P|Fang, B
PMID: 15592959
39.
Journal: Oncogene. 2005 Feb 17;24(8):1320-7.
Title: hTERT antagonizes p53-induced apoptosis independently of telomerase activity.
Author: Rahman, Rubaiyat|Latonen, Leena|Wiman, Klas G
PMID: 15608686
40.
Journal: Chin J Dig Dis. 2005;6(1):15-20.
Title: Experimental study of the killing effects of oxymatrine on human colon cancer cell line SW1116.
Author: Zou, Jian|Ran, Zhi Hua|Xu, Qi|Xiao, Shu Dong
PMID: 15667553
41.
Journal: World J Gastroenterol. 2005 Feb 14;11(6):785-90.
Title: Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line.
Author: Fu, Xiao-Hua|Zhang, Jian-Song|Zhang, Na|Zhang, Yang-De
PMID: 15682468
42.
Journal: Cancer Res. 2005 Mar 15;65(6):2321-9.
Title: Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells.
Author: Dalerba, Piero|Guiducci, Cristiana|Poliani, Pietro Luigi|Cifola, Ingrid|Parenza, Mariella|Frattini, Milo|Gallino, Gianfrancesco|Carnevali, Ileana|Di Giulio, Ilvia|Andreola, Salvatore|Lombardo, Claudia|Rivoltini, Licia|Schweighoffer, Tamas|Belli, Filiberto
PMID: 15781646
43.
Journal: Exp Cell Res. 2005 May 1;305(2):300-11.
Title: Survivin enhances telomerase activity via up-regulation of specificity protein 1- and c-Myc-mediated human telomerase reverse transcriptase gene transcription.
Author: Endoh, Teruo|Tsuji, Naoki|Asanuma, Koichi|Yagihashi, Atsuhito|Watanabe, Naoki
PMID: 15817155
44.
Journal: Int J Cancer. 2005 Sep 1;116(3):395-400.
Title: hTERT gene copy number is not associated with hTERT RNA expression or telomerase activity in colorectal cancer.
Author: Palmqvist, Richard|Zhang, Anju|Xu, Dawei|Golovleva, Irina|Norrback, Karl-Fredrik|Gruber, Astrid|Oberg, Ake|Stenling, Roger|Roos, Goran
PMID: 15818616
45.
Journal: Hepatogastroenterology. 2005 Jul-Aug;52(64):985-9.
Title: Expression pattern of telomerase reverse transcriptase in rectal carcinoma predicts tumor radiosensitivity, local recurrence and disease-free survival.
Author: Komuro, Yasuhiro|Watanabe, Toshiaki|Tsurita, Giichiro|Muto, Tetsuichiro|Nagawa, Hirokazu
PMID: 16001613
46.
Journal: Org Lett. 2005 Jul 21;7(15):3155-7.
Title: 1-Deoxy-5-hydroxysphingolipids as new anticancer principles: an efficient procedure for stereoselective syntheses of 2-amino-3,5-diols.
Author: Wiseman, John M|McDonald, Frank E|Liotta, Dennis C
PMID: 16018609
47.
Journal: J Gastroenterol Hepatol. 2005 Oct;20(10):1578-83.
Title: Clinical usefulness of telomerase for the detection of colon cancer in ulcerative colitis patients.
Author: Myung, Seung-Jae|Yang, Suk-Kyun|Chang, Hye-Sook|Byeon, Jeong-Sik|Kim, Kyu-Jong|Hong, Seong Soo|Jeong, Jin-Yong|Lee, Sun-Mi|Hong, Weon-Seon|Kim, Jin-Ho|Min, Young Il
PMID: 16174077
48.
Journal: Cancer Biol Ther. 2005 Oct;4(10):1098-103. Epub 2005 Oct 13.
Title: Intensive inhibition of hTERT expression by a ribozyme induces rapid apoptosis of cancer cells through a telomere length-independent pathway.
Author: Hao, Zhi-Ming|Luo, Jin-Yan|Cheng, Jin|Li, Lei|He, Daling|Wang, Quan-Ying|Yang, Guang-Xiao
PMID: 16205109
49.
Journal: Cancer. 2006 Mar 15;106(6):1243-9.
Title: Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma.
Author: He, Hua|Xia, Harry Hua-Xiang|Wang, Ji De|Gu, Qing|Lin, Marie C M|Zou, Bing|Lam, Shiu Kum|Chan, Annie O O|Yuen, Man Fung|Kung, Hsiang Fu|Wong, Benjamin Chun-Yu
PMID: 16444744
50.
Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 Jan;35(1):45-9.
Title: [Activity of the TNF-related apoptosis-inducing ligand gene expressed from the hTERT promoter on colon cancer cell line HT-29].
Author: Chen, Bin|He, Chao|Lao, Wei-feng|Huang, Xue-feng|Fang, Bing-liang
PMID: 16470920
51.
Journal: World J Gastroenterol. 2006 Jan 21;12(3):465-7.
Title: Telomerase activity and human telomerase reverse transcriptase expression in colorectal carcinoma.
Author: Liu, Jian-Lun|Ge, Lian-Ying|Zhang, Gui-Nian
PMID: 16489651
52.
Journal: Oncogene. 2006 Jul 27;25(32):4413-20.
Title: Telomere dysfunction and loss of p53 cooperate in defective mitotic segregation of chromosomes in cancer cells.
Author: Pantic, M|Zimmermann, S|El Daly, H|Opitz, O G|Popp, S|Boukamp, P|Martens, U M
PMID: 16547498
53.
Journal: Hepatogastroenterology. 2006 Mar-Apr;53(68):188-91.
Title: Telomerase subunit immunoreactivity and recurrence in colorectal cancer.
Author: Ohnishi, Tatsuya|Watanabe, Toshiaki|Nozawa, Hiroaki|Nagawa, Hirokazu
PMID: 16608021
54.
Journal: Oncogene. 2006 Aug 3;25(33):4505-14. Epub 2006 Apr 17.
Title: hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.
Author: Massard, C|Zermati, Y|Pauleau, A-L|Larochette, N|Metivier, D|Sabatier, L|Kroemer, G|Soria, J-C
PMID: 16619047
55.
Journal: World J Surg. 2006 Jun;30(6):1007-13.
Title: Molecular detection of circulating tumor cells in the peripheral blood of patients with colorectal cancer using RT-PCR: significance of the prediction of postoperative metastasis.
Author: Wang, Jaw-Yuan|Wu, Chan-Han|Lu, Chien-Yu|Hsieh, Jan-Sing|Wu, Deng-Chyang|Huang, Sung-Yu|Lin, Shiu-Ru
PMID: 16736329
56.
Journal: Int J Hyperthermia. 2006 Jun;22(4):301-18.
Title: Influence of neoadjuvant radiochemotherapy combined with hyperthermia on the quality of life in rectum cancer patients.
Author: Schulze, T|Wust, P|Gellermann, J|Hildebrandt, B|Riess, H|Felix, R|Rau, B
PMID: 16754351
57.
Journal: Orv Hetil. 2006 Sep 24;147(38):1835-41.
Title: [Insulin-like growth factor receptor, hepatocyte-derived growth factor receptor and telomerase expression in ulcerative colitis].
Author: Sipos, Ferenc|Molnar, Bela|Zagoni, Tamas|Miheller, Pal|Tulassay, Zsolt
PMID: 17066600
58.
Journal: J Mol Med (Berl). 2006 Dec;84(12):1077-86. Epub 2006 Nov 1.
Title: Suppression of colorectal tumor growth by regulated survivin targeting.
Author: Li, Binghua|Fan, Junkai|Liu, Xinran|Qi, Rong|Bo, Linan|Gu, Jinfa|Qian, Cheng|Liu, Xinyuan
PMID: 17077982
59.
Journal: Cancer Res. 2007 Jan 1;67(1):194-201.
Title: hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site.
Author: Zinn, Rebekah L|Pruitt, Kevin|Eguchi, Sayaka|Baylin, Stephen B|Herman, James G
PMID: 17210699
60.
Journal: Biochem Pharmacol. 2007 Jun 1;73(11):1703-14. Epub 2007 Feb 1.
Title: Down-regulation of human telomerase reverse transcriptase through specific activation of RNAi pathway quickly results in cancer cell growth impairment.
Author: Gandellini, Paolo|Folini, Marco|Bandiera, Roberto|De Cesare, Michelandrea|Binda, Mara|Veronese, Silvio|Daidone, Maria Grazia|Zunino, Franco|Zaffaroni, Nadia
PMID: 17321502
61.
Journal: Gastroenterology. 2007 Mar;132(3):1066-76. Epub 2006 Dec 3.
Title: Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis.
Author: Wang, Jide|Yang, Yi|Xia, Harry H X|Gu, Qing|Lin, Marie C M|Jiang, Bo|Peng, Ying|Li, Guoqing|An, Xiaomeng|Zhang, Yali|Zhuang, Zehao|Zhang, Zhenshu|Kung, Hsiang Fu|Wong, Benjamin C Y
PMID: 17383428
62.
Journal: Clin Cancer Res. 2007 Apr 15;13(8):2406-13.
Title: Multiple molecular markers as predictors of colorectal cancer in patients with normal perioperative serum carcinoembryonic antigen levels.
Author: Wang, Jaw-Yuan|Lin, Shiu-Ru|Wu, Deng-Chyang|Lu, Chien-Yu|Yu, Fang-Jung|Hsieh, Jan-Sing|Cheng, Tian-Lu|Koay, Lok-Beng|Uen, Yih-Huei
PMID: 17406027
63.
Journal: Cancer Immunol Immunother. 2007 Nov;56(11):1755-63. Epub 2007 Apr 27.
Title: Identification of a new hTERT-derived HLA-A*0201 restricted, naturally processed CTL epitope.
Author: Thorn, Mette|Wang, Mingjun|Kloverpris, Henrik|Schmidt, Esben G W|Fomsgaard, Anders|Wenandy, Lynn|Berntsen, Annika|Brunak, Soren|Buus, Soren|Claesson, Mogens H
PMID: 17464507
64.
Journal: Cancer Res. 2007 May 15;67(10):4949-55.
Title: Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2.
Author: Schepelmann, Silke|Ogilvie, Lesley M|Hedley, Douglas|Friedlos, Frank|Martin, Janet|Scanlon, Ian|Chen, Ping|Marais, Richard|Springer, Caroline J
PMID: 17510425
65.
Journal: Cell Oncol. 2007;29(4):301-13.
Title: Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients.
Author: Soreide, Kjetil|Buter, Tirza C E|Janssen, Emiel A|Gudlaugsson, Einar|Skaland, Ivar|Korner, Hartwig|Baak, Jan P A
PMID: 17641414
66.
Journal: Biochem Biophys Res Commun. 2007 Sep 28;361(3):615-20.
Title: Site-specific methylation of CpG nucleotides in the hTERT promoter region can control the expression of hTERT during malignant progression of colorectal carcinoma.
Author: Choi, Jee-Hye|Park, Soo Hyun|Park, Jina|Park, Borae G|Cha, Seong-Jae|Kong, Kwang-Hoon|Lee, Kwang-Ho|Park, Ae Ja
PMID: 17673177
67.
Journal: Pathology. 2008 Jan;40(1):25-30.
Title: Real-time PCR quantification of human telomerase reverse transcriptase (hTERT) in colorectal cancer.
Author: Saleh, Said|Lam, Alfred King-Yin|Ho, Yik-Hong
PMID: 18038311
68.
Journal: Cancer Biol Ther. 2008 Feb;7(2):228-36. Epub 2007 Nov 3.
Title: hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells.
Author: Shen, Ying|Zhang, Yong-Wei|Zhang, Zhi-Xiang|Miao, Ze-Hong|Ding, Jian
PMID: 18059183
69.
Journal: J Nutr Biochem. 2008 Sep;19(9):587-93. Epub 2007 Dec 3.
Title: Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon.
Author: Waldecker, Markus|Kautenburger, Tanja|Daumann, Heike|Busch, Cordula|Schrenk, Dieter
PMID: 18061431
70.
Journal: Clin Cancer Res. 2008 Jan 1;14(1):281-90.
Title: Antitumor effects of systemically delivered adenovirus harboring trans-splicing ribozyme in intrahepatic colon cancer mouse model.
Author: Jeong, Jin-Sook|Lee, Seong-Wook|Hong, Seung-Hee|Lee, Yoon-Jong|Jung, Haeng-Im|Cho, Kyung-Sook|Seo, Hye-Hyun|Lee, Sang-Jin|Park, Sohee|Song, Min-Sun|Kim, Chang-Min|Kim, In-Hoo
PMID: 18172280
71.
Journal: Int J Colorectal Dis. 2008 Apr;23(4):389-400.
Title: Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.
Author: Soreide, Kjetil|Gudlaugsson, Einar|Skaland, Ivar|Janssen, Emiel A M|Van Diermen, Bianca|Korner, Hartwig|Baak, Jan P A
PMID: 18189140
72.
Journal: BMC Genomics. 2008 Jan 31;9:59.
Title: A novel method to quantify local CpG methylation density by regional methylation elongation assay on microarray.
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Title: hTERT expression in colorectal adenocarcinoma: correlations with p21, p53 expressions and clinicopathological features.
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Journal: Acta Pharmacol Sin. 2008 May;29(5):606-13.
Title: Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro.
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Journal: J Exp Clin Cancer Res. 2008 Aug 12;27:27.
Title: siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells.
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Journal: Scand J Gastroenterol. 2008 Mar;43(3):289-98.
Title: Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis.
Author: Sipos, Ferenc|Galamb, Orsolya|Herszenyi, Laszlo|Molnar, Bela|Solymosi, Norbert|Zagoni, Tamas|Berczi, Lajos|Tulassay, Zsolt
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Journal: Clin Cancer Res. 2008 Nov 15;14(22):7444-51.
Title: Relationship between tumor and plasma levels of hTERT mRNA in patients with colorectal cancer: implications for monitoring of neoplastic disease.
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Journal: Cancer Res. 2008 Dec 1;68(23):9865-74.
Title: Preventive vaccination with telomerase controls tumor growth in genetically engineered and carcinogen-induced mouse models of cancer.
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Title: Telomerase activity of blood samples and recurrence of colorectal cancer.
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Journal: Nucleosides Nucleotides Nucleic Acids. 2009;28(1):1-11.
Title: Downregulation of human telomerase reverse transcriptase through anti-C-myc siRNA in human colon cancer Colo 320 cells.
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Journal: Int J Oncol. 2009 Apr;34(4):1061-8.
Title: Interaction between survivin and aurora-B kinase plays an important role in survivin-mediated up-regulation of human telomerase reverse transcriptase expression.
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Title: Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells.
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Title: Suppression of cancer growth in mice by adeno-associated virus vector-mediated IFN-beta expression driven by hTERT promoter.
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Title: Retraction: siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells.
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Journal: Clin Cancer Res. 2009 Sep 1;15(17):5528-33.
Title: Tissue biomarker development in a multicentre trial context: a feasibility study on the PETACC3 stage II and III colon cancer adjuvant treatment trial.
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Title: [Effects of matrine on proliferation and telomerase activity of colon cancer SW1116 cells].
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Journal: Clin Cancer Res. 2009 Nov 15;15(22):6810-9.
Title: Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase.
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Title: [Expression of TEIF protein in colorectal tumors and its correlation with centrosome abnormality].
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Journal: Anticancer Res. 2009 Nov;29(11):4381-7.
Title: Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer.
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Journal: J Nutr Biochem. 2010 Sep;21(9):818-26.
Title: 4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.
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Title: Targeted antitumor effect induced by hTERT promoter mediated ODC antisense adenovirus.
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Title: Anti-cancer activity of nitrones in the Apc(Min/+) model of colorectal cancer.
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Title: PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells.
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Title: TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116.
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Journal: Inflamm Bowel Dis. 2010 Jul;16(7):1127-37.
Title: Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia.
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Title: Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models.
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Journal: Arch Neurol. 2010 Mar;67(3):275-8.
Title: New insights into susceptibility to glioma.
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Journal: Gastroenterol Hepatol. 2010 Apr;33(4):288-96.
Title: Telomerase mRNA expression and immunohistochemical detection as a biomarker of malignant transformation in patients with inflammatory bowel disease.
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Title: New orally bioavailable 2-aminobenzamide-type histone deacetylase inhibitor possessing a (2-hydroxyethyl)(4-(thiophen-2-yl)benzyl)amino group.
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Title: Molecular basis of the interaction of novel tributyltin(IV) 2/4-[(E)-2-(aryl)-1-diazenyl]benzoates endowed with an improved cytotoxic profile: synthesis, structure, biological efficacy and QSAR studies.
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Journal: Cancer Epidemiol Biomarkers Prev. 2010 Jul;19(7):1862-5.
Title: No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk.
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Title: Human telomerase reverse transcriptase expression in colorectal tumors: correlations with immunohistochemical expression and clinicopathologic features.
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Journal: Mol Biol Rep. 2011 Aug;38(6):3679-88.
Title: Cytotoxicity and genotoxicity of capecitabine in head and neck cancer and normal cells.
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Title: A broad spectrum anticancer nucleoside with selective toxicity against human colon cells in vitro.
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Title: Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: prognostic significance of detection for early relapse.
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Title: MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer.
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Title: DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.
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Title: Anti-cancer activity of nitrones and observations on mechanism of action.
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Title: The prognostic value of hTERT expression levels in advanced-stage colorectal cancer patients: a comparison between tissue and serum expression.
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Title: Telomerase-driven expression of the sodium iodide symporter (NIS) for in vivo radioiodide treatment of cancer: a new broad-spectrum NIS-mediated antitumor approach.
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Title: RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.
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Title: Novel positron emission tomography tracer distinguishes normal from cancerous cells.
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Title: Largazole and analogues with modified metal-binding motifs targeting histone deacetylases: synthesis and biological evaluation.
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Title: hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells.
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Title: Meta-analysis of new genome-wide association studies of colorectal cancer risk.
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Title: Telomere-specific reverse transcriptase (hTERT) and cell-free RNA in plasma as predictors of pathologic tumor response in rectal cancer patients receiving neoadjuvant chemoradiotherapy.
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Title: Telomerase expression as a predictive marker of radiotherapy response in rectal cancer.
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Title: Association of genetic variants of human telomerase with colorectal polyps and colorectal cancer risk.
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Title: The TERT variant rs2736100 is associated with colorectal cancer risk.
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Journal: Cell Cycle. 2012 Sep 1;11(17):3331-8.
Title: Human telomerase reverse transcriptase (hTERT) is a target gene of beta-catenin in human colorectal tumors.
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Title: The relative roles of charge and a recognition peptide in luminal targeting of colorectal cancer by fluorescent polyacrylamide.
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Title: Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study.
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Title: Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase beta.
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Title: Tetraphenylporphyrin tethered chitosan based carriers for photochemical transfection.
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Title: Effects of ginger supplementation on cell-cycle biomarkers in the normal-appearing colonic mucosa of patients at increased risk for colorectal cancer: results from a pilot, randomized, and controlled trial.
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Title: Telomerase is an independent prognostic marker of overall survival in patients with colorectal cancer.
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Title: Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells.
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Title: Overexpression of hTERT in potentially malignant colorectal laterally spreading tumors.
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Title: Synthesis, properties, and antitumor effects of a new mixed phosphine gold(I) compound in human colon cancer cells.
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Title: Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer.
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Title: Silencing of the hTERT gene by shRNA inhibits colon cancer SW480 cell growth in vitro and in vivo.
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Title: HCT116 colonospheres shows elevated expression of hTERT and beta-catenin protein - a short report.
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Title: Screening and preliminary validation of miRNAs with the regulation of hTERT in colorectal cancer.
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Title: Association between the TERT Genetic Polymorphism rs2853676 and Cancer Risk: Meta-Analysis of 76,108 Cases and 134,215 Controls.
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Title: Decreased expression of PinX1 protein predicts poor prognosis of colorectal cancer patients receiving 5-FU adjuvant chemotherapy.
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Title: Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells.
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Title: Telomerase Reverse Transcriptase (TERT) Gene Variations and Susceptibility of Colorectal Cancer.
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Title: A biotherapy based on PSCs-in-3D spheroid-ameliorated biologics depletes in vivo cancer-sustaining stem cells.
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Title: An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer.
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Title: Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway.
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Title: Clinical Relevance of Telomere Status and Telomerase Activity in Colorectal Cancer.
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Title: Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer.
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Title: Trifluoroselenomethionine: A New Unnatural Amino Acid.
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Title: [Apoptotic endonuclease EndoG induces alternative splicing of telomerase catalytic subunit hTERT and death of tumor cells].
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Title: Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients.
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Title: Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps.
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Title: Comparative profiling between primary colorectal carcinomas and metastases identifies heterogeneity on drug resistance.
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Title: Telomere Length, TERT, and miRNA Expression.
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Title: Bufalin Inhibits hTERT Expression and Colorectal Cancer Cell Growth by Targeting CPSF4.
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Title: Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.
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Title: Endosome Targeting meso-Tetraphenylchlorin-Chitosan Nanoconjugates for Photochemical Internalization.
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Title: CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.
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Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
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Title: Differences in telomerase activity and the effects of AZT in aneuploid and euploid cells in colon cancer.
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Title: Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo.
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Title: Proinflammatory Cytokines IL-6 and TNF-alpha Increased Telomerase Activity through NF-kappaB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells.
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Title: Hsa_circ_0020397 regulates colorectal cancer cell viability, apoptosis and invasion by promoting the expression of the miR-138 targets TERT and PD-L1.
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Title: Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashion.
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Title: Keratin 23 promotes telomerase reverse transcriptase expression and human colorectal cancer growth.
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Journal: Oncologist. 2017 Oct;22(10):1178-1188.
Title: TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker.
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Title: Changes in telomerase activity due to alternative splicing of human telomerase reverse transcriptase in colorectal cancer.
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Title: Relationship between the TERT, TNIP1 and OBFC1 genetic polymorphisms and susceptibility to colorectal cancer in Chinese Han population.
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Journal: Int J Oncol. 2017 Dec;51(6):1821-1830.
Title: GSK-3beta inhibitor 6-bromo-indirubin-3'-oxime promotes both adhesive activity and drug resistance in colorectal cancer cells.
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Journal: Nutr Cancer. 2017 Nov-Dec;69(8):1290-1299.
Title: Co-Delivery of Curcumin and Chrysin by Polymeric Nanoparticles Inhibit Synergistically Growth and hTERT Gene Expression in Human Colorectal Cancer Cells.
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Title: TERT rs2736098 (Ex2-659G>A) polymorphism and cancer susceptibility: evidence from a comprehensive meta-analysis.
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Title: Study of the role of telomerase in colorectal cancer: preliminary report and literature review.
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Journal: Curr Cancer Drug Targets. 2018;18(1):97-106.
Title: Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation.
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Title: Synergistic Effect of Free and Nano-encapsulated Chrysin-Curcumin on Inhibition of hTERT Gene Expression in SW480 Colorectal Cancer Cell Line.
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Title: Correction: Synergistic Effect of Free and Nano-encapsulated Chrysin-Curcumin on Inhibition of hTERT Gene Expression in SW480 Colorectal Cancer Cell Line.
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Journal: Br J Cancer. 2018 Mar 20;118(6):878-886.
Title: The predictive and prognostic potential of plasma telomerase reverse transcriptase (TERT) RNA in rectal cancer patients.
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Journal: Inflamm Bowel Dis. 2018 Feb 15;24(3):593-600.
Title: Nondysplastic Ulcerative Colitis Has High Levels of the Homologous Recombination Repair Protein NUCKS1 and Low Levels of the DNA Damage Marker Gamma-H2AX.
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Title: Absence of TERT promoter mutations in colorectal precursor lesions and cancer.
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Journal: Biomed Pharmacother. 2018 May;101:414-421.
Title: A silyl andrographolide analogue suppresses Wnt/beta-catenin signaling pathway in colon cancer.
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Journal: Oncotarget. 2018 Mar 30;9(24):16974-16987.
Title: Blood free-circulating DNA testing by highly sensitive methylation assay to diagnose colorectal neoplasias.
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Title: Author Correction: The predictive and prognostic potential of plasma telomerase reverse transcriptase (TERT) RNA in rectal cancer patients.
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Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
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Title: The expression of telomere-related proteins and DNA damage response and their association with telomere length in colorectal cancer in Saudi patients.
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Title: Apoptosis Induction and Antimigratory Activity of Andrographolide Analog (3A.1)-Incorporated Self-Assembled Nanoparticles in Cancer Cells.
Author: Kansom, Teeratas|Sajomsang, Warayuth|Saeeng, Rungnapha|Charoensuksai, Purin|Opanasopit, Praneet|Tonglairoum, Prasopchai
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Journal: Oncotarget. 2018 Aug 31;9(68):32943-32957.
Title: Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells.
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Title: Synthesis and biological evaluation of novel 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives as tubulin polymerization inhibitors.
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Title: Blackberry Extract Inhibits Telomerase Activity in Human Colorectal Cancer Cells.
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