Primary Site >> Colorectal Cancer
Gene >> TEK
| 1. | |||||||||||
| Journal: | Oncology (Williston Park). 2002 Apr;16(4 Suppl 3):31-5. | ||||||||||
| Title: | Angiopoietins and their role in colon cancer angiogenesis. | ||||||||||
| Author: | Ellis, Lee M|Ahmad, Syed|Fan, Fan|Liu, Wenbiao|Jung, Young Do|Stoeltzing, Oliver|Reinmuth, Niels|Parikh, Alexander A | ||||||||||
| PMID: | 12014866 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2003 Jun 15;63(12):3370-7. | ||||||||||
| Title: | Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors. | ||||||||||
| Author: | Stoeltzing, Oliver|Ahmad, Syed A|Liu, Wenbiao|McCarty, Marya F|Wey, Jane S|Parikh, Alexander A|Fan, Fan|Reinmuth, Niels|Kawaguchi, Michiya|Bucana, Corazon D|Ellis, Lee M | ||||||||||
| PMID: | 12810673 | ||||||||||
| 3. | |||||||||||
| Journal: | Hepatology. 2004 Feb;39(2):528-39. | ||||||||||
| Title: | Hepatic expression of ANG2 RNA in metastatic colorectal cancer. | ||||||||||
| Author: | Ogawa, Minoru|Yamamoto, Hirofumi|Nagano, Hiroaki|Miyake, Yasuhiro|Sugita, Yurika|Hata, Taishi|Kim, Byung-No|Ngan, Chew Yee|Damdinsuren, Bazarragchaa|Ikenaga, Masakazu|Ikeda, Masataka|Ohue, Masayuki|Nakamori, Shoji|Sekimoto, Mitsugu|Sakon, Masato|Matsuura, | ||||||||||
| PMID: | 14768007 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2004 Jul;53(7):600-8. | ||||||||||
| Title: | Angiopoietin decoy secreted at tumor site impairs tumor growth and metastases by inducing local inflammation and altering neoangiogenesis. | ||||||||||
| Author: | Melani, Cecilia|Stoppacciaro, Antonella|Foroni, Chiara|Felicetti, Federica|Care, Alessandra|Colombo, Mario P | ||||||||||
| PMID: | 14985859 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Res. 2005 Feb 1;65(3):957-66. | ||||||||||
| Title: | Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451. | ||||||||||
| Author: | Roberts, W Gregory|Whalen, Pamela M|Soderstrom, Erik|Moraski, Garrett|Lyssikatos, Joseph P|Wang, Huifen-F|Cooper, Beth|Baker, Deborah A|Savage, Douglas|Dalvie, Deepak|Atherton, James A|Ralston, Sherry|Szewc, Ruby|Kath, John C|Lin, Jing|Soderstrom, Cathy|T | ||||||||||
| PMID: | 15705896 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2005 Feb 1;65(3):972-81. | ||||||||||
| Title: | Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody. | ||||||||||
| Author: | Popkov, Mikhail|Jendreyko, Nina|McGavern, Dorian B|Rader, Christoph|Barbas, Carlos F 3rd | ||||||||||
| PMID: | 15705898 | ||||||||||
| 7. | |||||||||||
| Journal: | Am J Pathol. 2005 Dec;167(6):1753-62. | ||||||||||
| Title: | Heterogeneity of Tie2 expression in tumor microcirculation: influence of cancer type, implantation site, and response to therapy. | ||||||||||
| Author: | Fathers, Kelly E|Stone, Courtney M|Minhas, Kanwal|Marriott, Jason J A|Greenwood, Janice D|Dumont, Daniel J|Coomber, Brenda L | ||||||||||
| PMID: | 16314485 | ||||||||||
| 8. | |||||||||||
| Journal: | Stem Cells. 2006 Dec;24(12):2733-43. | ||||||||||
| Title: | Endothelial differentiation potential of human monocyte-derived multipotential cells. | ||||||||||
| Author: | Kuwana, Masataka|Okazaki, Yuka|Kodama, Hiroaki|Satoh, Takashi|Kawakami, Yutaka|Ikeda, Yasuo | ||||||||||
| PMID: | 16888284 | ||||||||||
| 9. | |||||||||||
| Journal: | J Surg Res. 2006 Mar;131(1):97-104. Epub 2005 Oct 20. | ||||||||||
| Title: | A comparison of antiangiogenic therapies for the prevention of liver metastases. | ||||||||||
| Author: | Mi, Jing|Sarraf-Yazdi, Shiva|Zhang, Xiuwu|Cao, Yiting|Dewhirst, Mark W|Kontos, Christopher D|Li, Chuan-Yuan|Clary, Bryan M | ||||||||||
| PMID: | 16242720 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Cancer. 2006 Feb 1;118(3):755-64. | ||||||||||
| Title: | Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy. | ||||||||||
| Author: | Zaman, Khalil|Driscoll, Robert|Hahn, Diane|Werffeli, Patricia|Goodman, Simon L|Bauer, Jean|Leyvraz, Serge|Lejeune, Ferdy|Stupp, Roger|Ruegg, Curzio | ||||||||||
| PMID: | 16114015 | ||||||||||
| 11. | |||||||||||
| Journal: | J Surg Res. 2008 May 1;146(1):16-23. Epub 2007 Oct 22. | ||||||||||
| Title: | Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer. | ||||||||||
| Author: | Sarraf-Yazdi, Shiva|Mi, Jing|Moeller, Benjamin J|Niu, Xilin|White, Rebekah R|Kontos, Christopher D|Sullenger, Bruce A|Dewhirst, Mark W|Clary, Bryan M | ||||||||||
| PMID: | 17950331 | ||||||||||
| 12. | |||||||||||
| Journal: | Eur J Cancer. 2008 Aug;44(12):1761-9. | ||||||||||
| Title: | Expression profiling of angiogenic genes for the characterisation of colorectal carcinoma. | ||||||||||
| Author: | Carrer, Alessandro|Zacchigna, Serena|Balani, Alessandro|Pistan, Valentina|Adami, Adelino|Porcelli, Fabio|Scaramucci, Monica|Roseano, Mauro|Turoldo, Angelo|Prati, Maria Cristina|Dell'Omodarme, Matteo|de Manzini, Nicolo'|Giacca, Mauro | ||||||||||
| PMID: | 18656346 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Sci. 2008 Dec;99(12):2373-9. | ||||||||||
| Title: | Angiopoietin-1 alters tumor growth by stabilizing blood vessels or by promoting angiogenesis. | ||||||||||
| Author: | Satoh, Naoyuki|Yamada, Yoshihiro|Kinugasa, Yumi|Takakura, Nobuyuki | ||||||||||
| PMID: | 19018775 | ||||||||||
| 14. | |||||||||||
| Journal: | Pol Merkur Lekarski. 2009 Dec;27(162):466-9. | ||||||||||
| Title: | [Assessment of the selected, late phase of angiogenesis factors' concentration in colorectal cancer patients]. | ||||||||||
| Author: | Wieloch, Maria|Swiatkowska, Magdalena|Libiszewski, Michal|Hedayati, Masoud|Drozda, Rafal|Kolomecki, Krzysztof | ||||||||||
| PMID: | 20120708 | ||||||||||
| 15. | |||||||||||
| Journal: | Surg Endosc. 2010 Oct;24(10):2581-7. | ||||||||||
| Title: | Minimally invasive colorectal resection for cancer is associated with a short-lived decrease in soluble Tie-2 receptor levels, which may transiently inhibit VEGF-mediated angiogenesis (via altered blood levels of free Ang-1 and Ang-2). | ||||||||||
| Author: | Shantha Kumara, H M C|Grieco, Michael J|Yan, Xiaohong|Kalady, Matthew F|DiMaggio, Vincent|Kim, Donald G|Hyman, Neil|Feingold, Daniel L|Whelan, Richard L | ||||||||||
| PMID: | 20354881 | ||||||||||
| 16. | |||||||||||
| Journal: | Nan Fang Yi Ke Da Xue Xue Bao. 2012 Nov;32(11):1658-62. | ||||||||||
| Title: | [Role of Ang-2, Tie-2 and VEGFR-2 in angiogenesis in colorectal carcinoma and their prognostic value]. | ||||||||||
| Author: | Liu, Xinlan|Li, Yigong|Wei, Jianmin|Zhao, Yanjiao | ||||||||||
| PMID: | 23174599 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2012;7(9):e44450. | ||||||||||
| Title: | Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer. | ||||||||||
| Author: | Schauer, Dominic|Starlinger, Patrick|Reiter, Christian|Jahn, Nikolaus|Zajc, Philipp|Buchberger, Elisabeth|Bachleitner-Hofmann, Thomas|Bergmann, Michael|Stift, Anton|Gruenberger, Thomas|Brostjan, Christine | ||||||||||
| PMID: | 22973451 | ||||||||||
| 18. | |||||||||||
| Journal: | Eur Cytokine Netw. 2012 Jun;23(2):68-71. | ||||||||||
| Title: | Plasma concentrations of angiopoietin-1, angiopoietin-2 and Tie-2 in colon cancer. | ||||||||||
| Author: | Engin, Huseyin|Ustundag, Yucel|Tekin, Ishak Ozel|Gokmen, Ayla|Ertop, Sehmuz|Ilikhan, Sevil Uygun | ||||||||||
| PMID: | 22728324 | ||||||||||
| 19. | |||||||||||
| Journal: | Expert Opin Investig Drugs. 2012 Jun;21(6):879-89. | ||||||||||
| Title: | Regorafenib for cancer. | ||||||||||
| Author: | Strumberg, Dirk|Schultheis, Beate | ||||||||||
| PMID: | 22577890 | ||||||||||
| 20. | |||||||||||
| Journal: | Eur J Pharmacol. 2012 Feb 29;677(1-3):22-30. | ||||||||||
| Title: | The anti-angiogenic and anti-tumor activity of synthetic phenylpropenone derivatives is mediated through the inhibition of receptor tyrosine kinases. | ||||||||||
| Author: | Lee, Jong-Suk|Kang, Youra|Kim, Jong Tae|Thapa, Dinesh|Lee, Eung-Seok|Kim, Jung-Ae | ||||||||||
| PMID: | 22200628 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Invest. 2012 Mar;30(3):225-30. | ||||||||||
| Title: | Analysis of Tie2-expressing monocytes (TEM) in patients with colorectal cancer. | ||||||||||
| Author: | Goede, Valentin|Coutelle, Oliver|Shimabukuro-Vornhagen, Alexander|Holtick, Udo|Neuneier, Janina|Koslowsky, Thomas C|Weihrauch, Martin R|von Bergwelt-Baildon, Michael|Hacker, Ulrich T | ||||||||||
| PMID: | 22171993 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Cancer. 2012 Jul 15;131(2):298-309. | ||||||||||
| Title: | Recombinant canstatin inhibits angiopoietin-1-induced angiogenesis and lymphangiogenesis. | ||||||||||
| Author: | Hwang-Bo, Jeon|Yoo, Ki Hyun|Park, Jong-Hwa|Jeong, Han-Sin|Chung, In Sik | ||||||||||
| PMID: | 21823121 | ||||||||||
| 23. | |||||||||||
| Journal: | Clin Cancer Res. 2012 May 1;18(9):2658-67. | ||||||||||
| Title: | A phase I dose-escalation study of regorafenib (BAY 73-4506), an inhibitor of oncogenic, angiogenic, and stromal kinases, in patients with advanced solid tumors. | ||||||||||
| Author: | Mross, Klaus|Frost, Annette|Steinbild, Simone|Hedbom, Susanne|Buchert, Martin|Fasol, Ulrike|Unger, Clemens|Kratzschmar, Jorn|Heinig, Roland|Boix, Oliver|Christensen, Olaf | ||||||||||
| PMID: | 22421192 | ||||||||||
| 24. | |||||||||||
| Journal: | Br J Cancer. 2013 Feb 19;108(3):503-11. | ||||||||||
| Title: | A randomised, double-blind, placebo-controlled phase 2 study of trebananib (AMG 386) in combination with FOLFIRI in patients with previously treated metastatic colorectal carcinoma. | ||||||||||
| Author: | Peeters, M|Strickland, A H|Lichinitser, M|Suresh, A V S|Manikhas, G|Shapiro, J|Rogowski, W|Huang, X|Wu, B|Warner, D|Jain, R|Tebbutt, N C | ||||||||||
| PMID: | 23361051 | ||||||||||
| 25. | |||||||||||
| Journal: | BioDrugs. 2013 Jun;27(3):213-24. | ||||||||||
| Title: | Regorafenib for gastrointestinal malignancies : from preclinical data to clinical results of a novel multi-target inhibitor. | ||||||||||
| Author: | Aprile, Giuseppe|Macerelli, Marianna|Giuliani, Francesco | ||||||||||
| PMID: | 23435872 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Manag Res. 2013 Apr 12;5:49-55. | ||||||||||
| Title: | Critical appraisal of the use of regorafenib in the management of colorectal cancer. | ||||||||||
| Author: | Festino, Lucia|Fabozzi, Alessio|Manzo, Anna|Gambardella, Valentina|Martinelli, Erika|Troiani, Teresa|De Vita, Ferdinando|Orditura, Michele|Ciardiello, Fortunato|Morgillo, Floriana | ||||||||||
| PMID: | 23610528 | ||||||||||
| 27. | |||||||||||
| Journal: | Nan Fang Yi Ke Da Xue Xue Bao. 2013 Aug;33(8):1236-9. | ||||||||||
| Title: | [Expression of angiopoietin-2 and vascular endothelial growth factor in human colon cancer]. | ||||||||||
| Author: | Wang, Ruihua|Xie, Jianguo|Chen, Hua|Ren, Tingting|Zhang, Yicui | ||||||||||
| PMID: | 23996775 | ||||||||||
| 28. | |||||||||||
| Journal: | Br J Cancer. 2013 Nov 26;109(11):2765-73. | ||||||||||
| Title: | Prognostic/predictive value of 207 serum factors in colorectal cancer treated with cediranib and/or chemotherapy. | ||||||||||
| Author: | Spencer, S K M|Pommier, A J C|Morgan, S R|Barry, S T|Robertson, J D|Hoff, P M|Jurgensmeier, J M | ||||||||||
| PMID: | 24149180 | ||||||||||
| 29. | |||||||||||
| Journal: | Phytother Res. 2014 Feb;28(2):219-23. | ||||||||||
| Title: | Impact of Phytolacca americana extracts on gene expression of colon cancer cells. | ||||||||||
| Author: | Maness, L|Goktepe, I|Chen, H|Ahmedna, M|Sang, S | ||||||||||
| PMID: | 23553997 | ||||||||||
| 30. | |||||||||||
| Journal: | Lab Invest. 2014 Nov;94(11):1296-308. | ||||||||||
| Title: | Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method. | ||||||||||
| Author: | Payton, Marc|Jun, Toni|Wayne, William|Yu, Dongyin|Manoukian, Raffi|Chung, Grace|Zhang, Nancy|Sun, Ji-Rong|Kaplan-Lefko, Paula|Scully, Sheila|Van, Gwyneth|Radinsky, Robert|Kendall, Richard|Oliner, Jonathan|Coxon, Angela | ||||||||||
| PMID: | 25243900 | ||||||||||
| 31. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2014;15(20):8651-6. | ||||||||||
| Title: | Expression of Ang-2/Tie-2 and PI3K/AKT in colorectal cancer. | ||||||||||
| Author: | Zhang, Ji-Hong|Wang, Li-Hua|Li, Xiang-Jun|Wang, Ai-Ping|Reng, Li-Qun|Xia, Feng-Guo|Yang, Zhi-Ping|Jiang, Jing|Wang, Xiao-Dan|Wen, Chun-Yang | ||||||||||
| PMID: | 25374184 | ||||||||||
| 32. | |||||||||||
| Journal: | World J Gastroenterol. 2015 Mar 7;21(9):2645-50. | ||||||||||
| Title: | Angiopoietin and vascular endothelial growth factor expression in colorectal disease models. | ||||||||||
| Author: | Liu, Wei-Xin|Gu, Shou-Zhi|Zhang, Shen|Ren, Yi|Sang, Li-Xuan|Dai, Cong | ||||||||||
| PMID: | 25759532 | ||||||||||
| 33. | |||||||||||
| Journal: | PLoS One. 2015 Jul 31;10(7):e0134406. | ||||||||||
| Title: | Differential Gene Expression in Colon Tissue Associated With Diet, Lifestyle, and Related Oxidative Stress. | ||||||||||
| Author: | Slattery, Martha L|Pellatt, Daniel F|Mullany, Lila E|Wolff, Roger K | ||||||||||
| PMID: | 26230583 | ||||||||||
| 34. | |||||||||||
| Journal: | J Cell Physiol. 2016 May;231(5):1097-105. | ||||||||||
| Title: | Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells. | ||||||||||
| Author: | Mirone, Giovanna|Perna, Stefania|Shukla, Arvind|Marfe, Gabriella | ||||||||||
| PMID: | 26419617 | ||||||||||
| 35. | |||||||||||
| Journal: | EMBO Mol Med. 2016 Feb 1;8(2):155-70. | ||||||||||
| Title: | IFNalpha gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. | ||||||||||
| Author: | Catarinella, Mario|Monestiroli, Andrea|Escobar, Giulia|Fiocchi, Amleto|Tran, Ngoc Lan|Aiolfi, Roberto|Marra, Paolo|Esposito, Antonio|Cipriani, Federica|Aldrighetti, Luca|Iannacone, Matteo|Naldini, Luigi|Guidotti, Luca G|Sitia, Giovanni | ||||||||||
| PMID: | 26769348 | ||||||||||
| 36. | |||||||||||
| Journal: | Cancer Sci. 2016 May;107(5):601-8. | ||||||||||
| Title: | Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma. | ||||||||||
| Author: | Takigawa, Hidehiko|Kitadai, Yasuhiko|Shinagawa, Kei|Yuge, Ryo|Higashi, Yukihito|Tanaka, Shinji|Yasui, Wataru|Chayama, Kazuaki | ||||||||||
| PMID: | 26865419 | ||||||||||
| 37. | |||||||||||
| Journal: | ChemMedChem. 2016 Aug 5;11(15):1587-95. | ||||||||||
| Title: | Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative Activity. | ||||||||||
| Author: | El-Damasy, Ashraf Kareem|Cho, Nam-Chul|Nam, Ghilsoo|Pae, Ae Nim|Keum, Gyochang | ||||||||||
| PMID: | 27405013 | ||||||||||
| 38. | |||||||||||
| Journal: | Oncoimmunology. 2016 Mar 22;5(6):e1160185. | ||||||||||
| Title: | Chemotherapy of colorectal liver metastases induces a rapid rise in intermediate blood monocytes which predicts treatment response. | ||||||||||
| Author: | Schauer, Dominic|Starlinger, Patrick|Alidzanovic, Lejla|Zajc, Philipp|Maier, Thomas|Feldman, Alexandra|Padickakudy, Robin|Buchberger, Elisabeth|Elleder, Vanessa|Spittler, Andreas|Stift, Judith|Pop, Lorand|Gruenberger, Birgit|Gruenberger, Thomas|Brostjan, | ||||||||||
| PMID: | 27471631 | ||||||||||
| 39. | |||||||||||
| Journal: | Oncol Lett. 2016 Oct;12(4):2828-2834. | ||||||||||
| Title: | 4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl inhibits angiogenesis by suppressing VEGFR2 and Tie2 phosphorylation. | ||||||||||
| Author: | Liu, Yuanyuan|Gao, Jing|Huang, Shuangsheng|Hu, Lamei|Wang, Zhiqiang|Wang, Zheyuan|Chen, Xiao|Zhang, Xiaoyu|Li, Wenguang | ||||||||||
| PMID: | 27698866 | ||||||||||
| 40. | |||||||||||
| Journal: | BMC Complement Altern Med. 2016 Nov 18;16(1):473. | ||||||||||
| Title: | Evaluation of anti-tumorigenic activity of BP3B against colon cancer with patient-derived tumor xenograft model. | ||||||||||
| Author: | Kim, Hye-Youn|Kim, Jinhee|Ha Thi, Huyen Trang|Bang, Ok-Sun|Lee, Won-Suk|Hong, Suntaek | ||||||||||
| PMID: | 27863496 | ||||||||||
| 41. | |||||||||||
| Journal: | Ann Coloproctol. 2017 Feb;33(1):9-15. | ||||||||||
| Title: | Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer. | ||||||||||
| Author: | Hong, Sunghoon|Jung, Hae Il|Ahn, Tae Sung|Kim, Han-Jo|Lee, Kyu-Taek|Baek, Moo-Jun|Bae, Sang-Byung | ||||||||||
| PMID: | 28289658 | ||||||||||
| 42. | |||||||||||
| Journal: | Cancer Med. 2017 Jun;6(6):1378-1388. | ||||||||||
| Title: | Elevated expression of Tie1 is accompanied by acquisition of cancer stemness properties in colorectal cancer. | ||||||||||
| Author: | Torigata, Miku|Yamakawa, Daishi|Takakura, Nobuyuki | ||||||||||
| PMID: | 28464467 | ||||||||||
| 43. | |||||||||||
| Journal: | J Agric Food Chem. 2017 Sep 27;65(38):8348-8355. | ||||||||||
| Title: | Using Ultra-Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry-Based Chemometrics for the Identification of Anti-angiogenic Biflavonoids from Edible Garcinia Species. | ||||||||||
| Author: | Li, Ping|Yue, Grace Gar-Lee|Kwok, Hin-Fai|Long, Chun-Lin|Lau, Clara Bik-San|Kennelly, Edward J | ||||||||||
| PMID: | 28926234 | ||||||||||
| 44. | |||||||||||
| Journal: | Clin Cancer Res. 2018 Apr 1;24(7):1536-1545. | ||||||||||
| Title: | First-in-Human Phase I Study of Single-agent Vanucizumab, A First-in-Class Bispecific Anti-Angiopoietin-2/Anti-VEGF-A Antibody, in Adult Patients with Advanced Solid Tumors. | ||||||||||
| Author: | Hidalgo, Manuel|Martinez-Garcia, Maria|Le Tourneau, Christophe|Massard, Christophe|Garralda, Elena|Boni, Valentina|Taus, Alvaro|Albanell, Joan|Sablin, Marie-Paule|Alt, Marie|Bahleda, Ratislav|Varga, Andrea|Boetsch, Christophe|Franjkovic, Izolda|Heil, Flor | ||||||||||
| PMID: | 29217526 | ||||||||||