Primary Site >> Colorectal Cancer
Gene >> TEK
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Ref: Angiopoietins and their role in colon cancer angiogenesis. PMID: 12014866 |
Ref: Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors. PMID: 12810673 |
Ref: Hepatic expression of ANG2 RNA in metastatic colorectal cancer. PMID: 14768007 Ref: Angiopoietin decoy secreted at tumor site impairs tumor growth and metastases by inducing local inflammation and altering neoangiogenesis. PMID: 14985859 |
Ref: Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451. PMID: 15705896 Ref: Targeting tumor angiogenesis with adenovirus-delivered anti-Tie-2 intrabody. PMID: 15705898 Ref: Heterogeneity of Tie2 expression in tumor microcirculation: influence of cancer type, implantation site, and response to therapy. PMID: 16314485 |
Ref: Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy. PMID: 16114015 Ref: A comparison of antiangiogenic therapies for the prevention of liver metastases. PMID: 16242720 Ref: Endothelial differentiation potential of human monocyte-derived multipotential cells. PMID: 16888284 |
Ref: Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer. PMID: 17950331 Ref: Expression profiling of angiogenic genes for the characterisation of colorectal carcinoma. PMID: 18656346 Ref: Angiopoietin-1 alters tumor growth by stabilizing blood vessels or by promoting angiogenesis. PMID: 19018775 |
Ref: [Assessment of the selected, late phase of angiogenesis factors' concentration in colorectal cancer patients]. PMID: 20120708 |
Ref: Minimally invasive colorectal resection for cancer is associated with a short-lived decrease in soluble Tie-2 receptor levels, which may transiently inhibit VEGF-mediated angiogenesis (via altered blood levels of free Ang-1 and Ang-2). PMID: 20354881 |
Ref: Recombinant canstatin inhibits angiopoietin-1-induced angiogenesis and lymphangiogenesis. PMID: 21823121 Ref: Analysis of Tie2-expressing monocytes (TEM) in patients with colorectal cancer. PMID: 22171993 Ref: The anti-angiogenic and anti-tumor activity of synthetic phenylpropenone derivatives is mediated through the inhibition of receptor tyrosine kinases. PMID: 22200628 Ref: A phase I dose-escalation study of regorafenib (BAY 73-4506), an inhibitor of oncogenic, angiogenic, and stromal kinases, in patients with advanced solid tumors. PMID: 22421192 Ref: Regorafenib for cancer. PMID: 22577890 Ref: Plasma concentrations of angiopoietin-1, angiopoietin-2 and Tie-2 in colon cancer. PMID: 22728324 Ref: Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer. PMID: 22973451 Ref: [Role of Ang-2, Tie-2 and VEGFR-2 in angiogenesis in colorectal carcinoma and their prognostic value]. PMID: 23174599 |
Ref: A randomised, double-blind, placebo-controlled phase 2 study of trebananib (AMG 386) in combination with FOLFIRI in patients with previously treated metastatic colorectal carcinoma. PMID: 23361051 Ref: Regorafenib for gastrointestinal malignancies : from preclinical data to clinical results of a novel multi-target inhibitor. PMID: 23435872 Ref: Critical appraisal of the use of regorafenib in the management of colorectal cancer. PMID: 23610528 Ref: [Expression of angiopoietin-2 and vascular endothelial growth factor in human colon cancer]. PMID: 23996775 Ref: Prognostic/predictive value of 207 serum factors in colorectal cancer treated with cediranib and/or chemotherapy. PMID: 24149180 |
Ref: Impact of Phytolacca americana extracts on gene expression of colon cancer cells. PMID: 23553997 Ref: Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method. PMID: 25243900 Ref: Expression of Ang-2/Tie-2 and PI3K/AKT in colorectal cancer. PMID: 25374184 |
Ref: Angiopoietin and vascular endothelial growth factor expression in colorectal disease models. PMID: 25759532 Ref: Differential Gene Expression in Colon Tissue Associated With Diet, Lifestyle, and Related Oxidative Stress. PMID: 26230583 |
Ref: Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells. PMID: 26419617 Ref: IFNalpha gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. PMID: 26769348 Ref: Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma. PMID: 26865419 Ref: Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative Activity. PMID: 27405013 Ref: Chemotherapy of colorectal liver metastases induces a rapid rise in intermediate blood monocytes which predicts treatment response. PMID: 27471631 Ref: 4-isothiocyanate-2, 2, 6, 6-tetramethyl piperidinooxyl inhibits angiogenesis by suppressing VEGFR2 and Tie2 phosphorylation. PMID: 27698866 Ref: Evaluation of anti-tumorigenic activity of BP3B against colon cancer with patient-derived tumor xenograft model. PMID: 27863496 |
Ref: Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer. PMID: 28289658 Ref: Elevated expression of Tie1 is accompanied by acquisition of cancer stemness properties in colorectal cancer. PMID: 28464467 Ref: Using Ultra-Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry-Based Chemometrics for the Identification of Anti-angiogenic Biflavonoids from Edible Garcinia Species. PMID: 28926234 |
Ref: First-in-Human Phase I Study of Single-agent Vanucizumab, A First-in-Class Bispecific Anti-Angiopoietin-2/Anti-VEGF-A Antibody, in Adult Patients with Advanced Solid Tumors. PMID: 29217526 |