Primary Site >> Colorectal Cancer

Gene >> TDP1

Journal: Clin Cancer Res. 2008 Mar 15;14(6):1788-96.
Title: Irinotecan pharmacogenetics: influence of pharmacodynamic genes.
Author: Hoskins, Janelle M|Marcuello, Eugenio|Altes, Albert|Marsh, Sharon|Maxwell, Taylor|Van Booven, Derek J|Pare, Laia|Culverhouse, Robert|McLeod, Howard L|Baiget, Montserrat
PMID: 18347181
Journal: J Agric Food Chem. 2008 Oct 8;56(19):8891-6.
Title: Impact of delphinidin on the maintenance of DNA integrity in human colon carcinoma cells.
Author: Fritz, Jessica|Roth, Matthias|Holbach, Peter|Esselen, Melanie|Marko, Doris
PMID: 18778064
Journal: Curr Med Chem. 2012;19(23):3874-85.
Title: DNA repair and resistance to topoisomerase I inhibitors: mechanisms, biomarkers and therapeutic targets.
Author: Alagoz, M|Gilbert, D C|El-Khamisy, S|Chalmers, A J
PMID: 22788763
Journal: Mol Cancer Ther. 2015 Feb;14(2):575-85.
Title: Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan.
Author: Meisenberg, Cornelia|Gilbert, Duncan C|Chalmers, Anthony|Haley, Vikki|Gollins, Simon|Ward, Simon E|El-Khamisy, Sherif F
PMID: 25522766
Journal: Nucleic Acids Res. 2017 Feb 17;45(3):1159-1176.
Title: Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan.
Author: Meisenberg, Cornelia|Ashour, Mohamed E|El-Shafie, Lamia|Liao, Chunyan|Hodgson, Adam|Pilborough, Alice|Khurram, Syed A|Downs, Jessica A|Ward, Simon E|El-Khamisy, Sherif F
PMID: 28180300
Journal: Eur J Pharm Sci. 2018 Jan 1;111:337-348.
Title: Synthesis, anti-cancer screening and tyrosyl-DNA phosphodiesterase 1 (Tdp1) inhibition activity of novel piperidinyl sulfamides.
Author: Jun, Jung Ho|Kumar, Vineet|Dexheimer, Thomas S|Wedlich, Iwona|Nicklaus, Marc C|Pommier, Yves|Malhotra, Sanjay V
PMID: 29037996