Primary Site >> Colorectal Cancer
Gene >> TDP1
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Ref: Irinotecan pharmacogenetics: influence of pharmacodynamic genes. PMID: 18347181 Ref: Impact of delphinidin on the maintenance of DNA integrity in human colon carcinoma cells. PMID: 18778064 |
Ref: DNA repair and resistance to topoisomerase I inhibitors: mechanisms, biomarkers and therapeutic targets. PMID: 22788763 |
Ref: Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan. PMID: 25522766 |
Ref: Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. PMID: 28180300 |
Ref: Synthesis, anti-cancer screening and tyrosyl-DNA phosphodiesterase 1 (Tdp1) inhibition activity of novel piperidinyl sulfamides. PMID: 29037996 |