Primary Site >> Colorectal Cancer

Gene >> TCF7L2

Journal: Science. 1997 Mar 21;275(5307):1787-90.
Title: Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.
Author: Morin, P J|Sparks, A B|Korinek, V|Barker, N|Clevers, H|Vogelstein, B|Kinzler, K W
PMID: 9065402
Journal: Science. 1998 Sep 4;281(5382):1509-12.
Title: Identification of c-MYC as a target of the APC pathway.
Author: He, T C|Sparks, A B|Rago, C|Hermeking, H|Zawel, L|da Costa, L T|Morin, P J|Vogelstein, B|Kinzler, K W
PMID: 9727977
Journal: Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):303-6.
Title: [beta-catenin overexpression in metastasized colorectal carcinoma--an important mechanism in progression of the disease?].
Author: Mann, B|Gratchev, A|Riede, E|Schmidt-Wolf, I|Trojanek, B|Moyer, P|Hanski, C|Buhr, H J
PMID: 14518265
Journal: Biochem Biophys Res Commun. 1999 Mar 24;256(3):584-90.
Title: Identification of Tcf4 residues involved in high-affinity beta-catenin binding.
Author: Omer, C A|Miller, P J|Diehl, R E|Kral, A M
PMID: 10080941
Journal: Genes Chromosomes Cancer. 2000 Sep;29(1):33-9.
Title: Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation.
Author: Planck, M|Wenngren, E|Borg, A|Olsson, H|Nilbert, M
PMID: 10918391
Journal: Cancer Res. 2000 Sep 1;60(17):4761-6.
Title: Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis.
Author: Yamada, T|Takaoka, A S|Naishiro, Y|Hayashi, R|Maruyama, K|Maesawa, C|Ochiai, A|Hirohashi, S
PMID: 10987283
Journal: Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12103-8.
Title: Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.
Author: Playford, M P|Bicknell, D|Bodmer, W F|Macaulay, V M
PMID: 11035789
Journal: Verh Dtsch Ges Pathol. 2000;84:175-81.
Title: [beta-Catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma].
Author: Brabletz, T|Jung, A|Dag, S|Reu, S|Kirchner, T
PMID: 11217438
Journal: Cancer Res. 2001 Feb 1;61(3):854-8.
Title: A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics.
Author: Wakita, K|Tetsu, O|McCormick, F
PMID: 11221869
Journal: J Virol. 2001 Mar;75(6):2857-65.
Title: Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway.
Author: Brunori, M|Malerba, M|Kashiwazaki, H|Iggo, R
PMID: 11222711
Journal: Cancer Res. 2001 Mar 15;61(6):2751-8.
Title: Restoration of epithelial cell polarity in a colorectal cancer cell line by suppression of beta-catenin/T-cell factor 4-mediated gene transactivation.
Author: Naishiro, Y|Yamada, T|Takaoka, A S|Hayashi, R|Hasegawa, F|Imai, K|Hirohashi, S
PMID: 11289158
Journal: Nat Genet. 2001 May;28(1):53-7.
Title: Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer.
Author: Hovanes, K|Li, T W|Munguia, J E|Truong, T|Milovanovic, T|Lawrence Marsh, J|Holcombe, R F|Waterman, M L
PMID: 11326276
Journal: J Biol Chem. 2001 Nov 30;276(48):45113-9. Epub 2001 Sep 25.
Title: Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma.
Author: Rockman, S P|Currie, S A|Ciavarella, M|Vincan, E|Dow, C|Thomas, R J|Phillips, W A
PMID: 11572874
Journal: Nat Struct Biol. 2001 Dec;8(12):1048-52.
Title: Tcf4 can specifically recognize beta-catenin using alternative conformations.
Author: Graham, T A|Ferkey, D M|Mao, F|Kimelman, D|Xu, W
PMID: 11713475
Journal: Oncol Res. 2001;12(11-12):469-76.
Title: Involvement of claudin-1 in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers.
Author: Miwa, N|Furuse, M|Tsukita, S|Niikawa, N|Nakamura, Y|Furukawa, Y
PMID: 11939410
Journal: Genes Chromosomes Cancer. 2002 Jan;33(1):73-81.
Title: Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability.
Author: Shimizu, Yosuke|Ikeda, Satoshi|Fujimori, Masahiko|Kodama, Shinya|Nakahara, Masahiro|Okajima, Masazumi|Asahara, Toshimasa
PMID: 11746989
Journal: Int J Cancer. 2002 Jan 1;97(1):42-51.
Title: Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate.
Author: Bordonaro, Michael|Lazarova, Darina L|Augenlicht, Leonard H|Sartorelli, Alan C
PMID: 11774242
Journal: Cell Mol Biol Lett. 2002;7(1):92-5.
Title: Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.
Author: Potocnik, Uros|Ravnik-Glavac, Metka|Glavac, Damjan
PMID: 11980438
Journal: Cancer Genet Cytogenet. 2002 Apr 1;134(1):46-54.
Title: Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer.
Author: Planck, Maria|Halvarsson, Britta|Palsson, Eva|Hallen, Magnus|Ekelund, Mats|Palsson, Birger|Baldetorp, Bo|Nilbert, Mef
PMID: 11996796
Journal: FEBS Lett. 2002 May 8;518(1-3):83-7.
Title: Stimulation of Cdx1 by oncogenic beta-catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein.
Author: Domon-Dell, Claire|Freund, Jean-Noel
PMID: 11997022
Journal: Cancer Res. 2002 Oct 15;62(20):5651-6.
Title: Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Author: Takahashi, Meiko|Fujita, Manabu|Furukawa, Yoichi|Hamamoto, Ryuji|Shimokawa, Takashi|Miwa, Nobutomo|Ogawa, Michio|Nakamura, Yusuke
PMID: 12384519
Journal: Oncogene. 2002 Nov 28;21(54):8340-6.
Title: The suppression of colon cancer cell growth in nude mice by targeting beta-catenin/TCF pathway.
Author: Kwong, Ka Yin|Zou, Yiyu|Day, Chi-Ping|Hung, Mien-Chie
PMID: 12447697
Journal: J Nutr. 2002 Dec;132(12):3804S-3808S.
Title: Short chain fatty acids and colon cancer.
Author: Augenlicht, Leonard H|Mariadason, John M|Wilson, Andrew|Arango, Diego|Yang, WanCai|Heerdt, Barbara G|Velcich, Anna
PMID: 12468628
Journal: Mol Cancer Ther. 2003 Jan;2(1):113-21.
Title: Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy.
Author: Kirmizis, Antonis|Bartley, Stephanie M|Farnham, Peggy J
PMID: 12533679
Journal: Cancer Res. 2003 Feb 1;63(3):728-34.
Title: Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways.
Author: Araki, Yuzuru|Okamura, Shu|Hussain, S Perwez|Nagashima, Makoto|He, Peijun|Shiseki, Masayuki|Miura, Koh|Harris, Curtis C
PMID: 12566320
Journal: Mamm Genome. 2003 Feb;14(2):119-29.
Title: Exclusion of Madh2, Madh4, and Madh7 as candidates for the modifier of Min 2 (Mom2) locus.
Author: Silverman, Karen A|Koratkar, Revati A|Siracusa, Linda D|Buchberg, Arthur M
PMID: 12584607
Journal: Comp Hepatol. 2003 Jan 31;2(1):3.
Title: Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease.
Author: Boitier, Eric|Gautier, Jean-Charles|Roberts, Ruth
PMID: 12622871
Journal: J Biol Chem. 2003 May 30;278(22):20259-67. Epub 2003 Mar 21.
Title: The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway.
Author: Ghiselli, Giancarlo|Coffee, Nefeteria|Munnery, Christine E|Koratkar, Revati|Siracusa, Linda D
PMID: 12651860
Journal: J Biol Chem. 2003 Jul 18;278(29):26511-6. Epub 2003 Apr 30.
Title: Synergistic cooperation between the beta-catenin signaling pathway and steroidogenic factor 1 in the activation of the Mullerian inhibiting substance type II receptor.
Author: Hossain, Anwar|Saunders, Grady F
PMID: 12724325
Journal: EMBO Rep. 2003 Jun;4(6):609-15.
Title: Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector.
Author: van de Wetering, Marc|Oving, Irma|Muncan, Vanesa|Pon Fong, Menno Tjon|Brantjes, Helen|van Leenen, Dik|Holstege, Frank C P|Brummelkamp, Thijn R|Agami, Reuven|Clevers, Hans
PMID: 12776180
Journal: Dev Biol. 2003 Jul 15;259(2):258-71.
Title: Wnt signaling during development of the gastrointestinal tract.
Author: Theodosiou, Nicole A|Tabin, Clifford J
PMID: 12871700
Journal: Int J Cancer. 2003 Nov 1;107(2):229-37.
Title: Overexpression of the beta-catenin binding domain of cadherin selectively kills colorectal cancer cells.
Author: Pierce, Michael|Wang, Chunwei|Stump, Mark|Kamb, Alexander
PMID: 12949799
Journal: Cancer Res. 2003 Oct 1;63(19):6116-20.
Title: Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Author: Shimokawa, Takashi|Furukawa, Yoichi|Sakai, Michihiro|Li, Meihua|Miwa, Nobutomo|Lin, Yu-Min|Nakamura, Yusuke
PMID: 14559787
Journal: Cancer Cell. 2004 Jan;5(1):5-6.
Title: Wnt breakers in colon cancer.
Author: Clevers, Hans
PMID: 14749120
Journal: Nat Genet. 2004 Mar;36(3):277-82. Epub 2004 Feb 8.
Title: Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation.
Author: van den Brink, Gijs R|Bleuming, Sylvia A|Hardwick, James C H|Schepman, Berber L|Offerhaus, G Johan|Keller, Josbert J|Nielsen, Corinne|Gaffield, William|van Deventer, Sander J H|Roberts, Drucilla J|Peppelenbosch, Maikel P
PMID: 14770182
Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Mar;33(2):108-14.
Title: [Alterations of p53 gene and microsatellite instability in ulcerative colitis and ulcerative colitis-associated colorectal cancer].
Author: Li, Jun|Lai, Mao-de|Huang, Qiong
PMID: 15067728
Journal: Nucleic Acids Res. 2004 May 11;32(8):2660-74.
Title: Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells.
Author: Bordonaro, Michael|Lazarova, Darina L|Sartorelli, Alan C
PMID: 15141037
Journal: Ai Zheng. 2004 Jul;23(7):737-41.
Title: [Indomethacin induces apoptosis through inhibition of survivin regulated by beta-catenin/TCF4 in human colorectal cancer cells].
Author: Zhu, Hong-Xia|Zhang, Guo|Wang, Yi-Hua|Zhou, Cui-Qi|Bai, Jin-Feng|Xu, Ning-Zhi
PMID: 15248904
Journal: Oncogene. 2005 Jan 20;24(4):597-604.
Title: beta-Catenin activates the growth factor endothelin-1 in colon cancer cells.
Author: Kim, Tae Hoon|Xiong, Hui|Zhang, Zhuohua|Ren, Bing
PMID: 15558022
Journal: Oncogene. 2005 Feb 3;24(6):1098-103.
Title: The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer.
Author: Gonzalez-Sancho, Jose Manuel|Aguilera, Oscar|Garcia, Jose Miguel|Pendas-Franco, Natalia|Pena, Cristina|Cal, Santiago|Garcia de Herreros, Antonio|Bonilla, Felix|Munoz, Alberto
PMID: 15592505
Journal: Chin Med J (Engl). 2005 Jan 20;118(2):136-40.
Title: Expression of T cell factor-4 in non-small-cell lung cancer.
Author: Li, Chun-yan|Wang, Yan|Cui, Ze-shi|Wang, En-hua
PMID: 15667799
Journal: Cancer Res. 2005 Jan 15;65(2):493-8.
Title: Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3).
Author: Chakrabarty, Subhas|Wang, Hongmei|Canaff, Lucie|Hendy, Geoffrey N|Appelman, Henry|Varani, James
PMID: 15695391
Journal: Am J Pathol. 2005 Apr;166(4):1239-46.
Title: Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice.
Author: Yang, Wancai|Velcich, Anna|Lozonschi, Ioana|Liang, Jiao|Nicholas, Courtney|Zhuang, Min|Bancroft, Laura|Augenlicht, Leonard H
PMID: 15793302
Journal: Biochem J. 2005 Sep 1;390(Pt 2):493-9.
Title: The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway.
Author: Ghiselli, Giancarlo|Agrawal, Amit
PMID: 15853773
Journal: J Biol Chem. 2005 Jul 15;280(28):26565-72. Epub 2005 May 17.
Title: Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer.
Author: Shao, Jinyi|Jung, Chaeyong|Liu, Chunming|Sheng, Hongmiao
PMID: 15899904
Journal: Br J Cancer. 2005 Jun 20;92(12):2233-9.
Title: HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation.
Author: Jung, C|Kim, R-S|Zhang, H|Lee, S-J|Sheng, H|Loehrer, P J|Gardner, T A|Jeng, M-H|Kao, C
PMID: 15928669
Journal: Biochim Biophys Acta. 2005 Jun 15;1735(1):30-40. Epub 2005 Feb 16.
Title: Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: effects on proliferation, differentiation, and gene expression.
Author: Lampen, A|Leifheit, M|Voss, J|Nau, H
PMID: 15935729
Journal: Gastroenterology. 2005 Jun;128(7):1907-18.
Title: Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta.
Author: Li, Jingnan|Mizukami, Yusuke|Zhang, Xiaobo|Jo, Won-Seok|Chung, Daniel C
PMID: 15940626
Journal: Gastroenterology. 2005 Jun;128(7):1919-36.
Title: Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex.
Author: Idogawa, Masashi|Yamada, Tesshi|Honda, Kazufumi|Sato, Satoshi|Imai, Kohzoh|Hirohashi, Setsuo
PMID: 15940627
Journal: Am J Pathol. 2005 Jul;167(1):233-42.
Title: The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis.
Author: Brouland, Jean-Philippe|Gelebart, Pascal|Kovacs, Tunde|Enouf, Jocelyne|Grossmann, Johannes|Papp, Bela
PMID: 15972967
Journal: Nature. 2005 Jun 23;435(7045):1126-30.
Title: EphB receptor activity suppresses colorectal cancer progression.
Author: Batlle, Eduard|Bacani, Julinor|Begthel, Harry|Jonkheer, Suzanne|Gregorieff, Alexander|van de Born, Maaike|Malats, Nuria|Sancho, Elena|Boon, Elles|Pawson, Tony|Gallinger, Steven|Pals, Steven|Clevers, Hans
PMID: 15973414
Journal: Cancer Lett. 2006 Feb 20;233(1):165-71.
Title: Genetic and cellular characterizations of human TCF4 with microsatellite instability in colon cancer and leukemia cell lines.
Author: Chang, Huoy-Rou|Cheng, Tian-Lu|Liu, Tsan-Zon|Hu, Han-Shu|Hsu, Li-Sung|Tseng, Wei-Chang|Chen, Ching-Hsein|Tsao, Der-An
PMID: 15905022
Journal: Dis Colon Rectum. 2006 Mar;49(3):399-406.
Title: Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer.
Author: Yamaguchi, Tatsuro|Iijima, Takeru|Mori, Takeo|Takahashi, Keiichi|Matsumoto, Hiroshi|Miyamoto, Hidenori|Hishima, Tsunekazu|Miyaki, Michiko
PMID: 16421660
Journal: J Cell Sci. 2006 Mar 1;119(Pt 5):819-27. Epub 2006 Feb 14.
Title: APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
Author: Park, Ki-Sook|Jeon, Soung Hoo|Kim, Sung-Eun|Bahk, Young-Yil|Holmen, Sheri L|Williams, Bart O|Chung, Kwang-Chul|Surh, Young-Joon|Choi, Kang-Yell
PMID: 16478791
Journal: Cancer Res. 2006 Feb 15;66(4):2279-86.
Title: SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling.
Author: Coluccia, Addolorata Maria Luce|Benati, Daniela|Dekhil, Hafedh|De Filippo, Annamaria|Lan, Cathy|Gambacorti-Passerini, Carlo
PMID: 16489032
Journal: J Biol Chem. 2006 Jun 2;281(22):15405-11. Epub 2006 Mar 28.
Title: Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells.
Author: Tzeng, Shu-Ling|Cheng, Yu-Wen|Li, Ching-Hao|Lin, Young-Sun|Hsu, Hey-Chi|Kang, Jaw-Jou
PMID: 16569639
Journal: Cancer Res. 2006 Aug 1;66(15):7571-7.
Title: Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.
Author: Shelton, Dawne N|Sandoval, Imelda T|Eisinger, Annie|Chidester, Stephanie|Ratnayake, Anokha|Ireland, Chris M|Jones, David A
PMID: 16885356
Journal: Mol Cell Biol. 2006 Nov;26(22):8418-26. Epub 2006 Sep 5.
Title: Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.
Author: Muncan, Vanesa|Sansom, Owen J|Tertoolen, Leon|Phesse, Toby J|Begthel, Harry|Sancho, Elena|Cole, Alicia M|Gregorieff, Alex|de Alboran, Ignacio Moreno|Clevers, Hans|Clarke, Alan R
PMID: 16954380
Journal: Oncogene. 2006 Dec 4;25(57):7531-7.
Title: Colorectal cancer and genetic alterations in the Wnt pathway.
Author: Segditsas, S|Tomlinson, I
PMID: 17143297
Journal: J Biol Chem. 2007 Jan 12;282(2):871-8. Epub 2006 Nov 22.
Title: An antisense transcript induced by Wnt/beta-catenin signaling decreases E2F4.
Author: Yochum, Gregory S|Cleland, Ryan|McWeeney, Shannon|Goodman, Richard H
PMID: 17121828
Journal: Gastroenterology. 2007 Feb;132(2):628-32. Epub 2006 Aug 18.
Title: The Intestinal Wnt/TCF Signature.
Author: Van der Flier, Laurens G|Sabates-Bellver, Jacob|Oving, Irma|Haegebarth, Andrea|De Palo, Mariagrazia|Anti, Marcello|Van Gijn, Marielle E|Suijkerbuijk, Saskia|Van de Wetering, Marc|Marra, Giancarlo|Clevers, Hans
PMID: 17320548
Journal: Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3324-9. Epub 2007 Feb 21.
Title: Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells.
Author: Yochum, Gregory S|McWeeney, Shannon|Rajaraman, Veena|Cleland, Ryan|Peters, Sandra|Goodman, Richard H
PMID: 17360646
Journal: Gastroenterology. 2007 Mar;132(3):1039-54. Epub 2007 Jan 5.
Title: Involvement of splicing factor-1 in beta-catenin/T-cell factor-4-mediated gene transactivation and pre-mRNA splicing.
Author: Shitashige, Miki|Naishiro, Yasuyoshi|Idogawa, Masashi|Honda, Kazufumi|Ono, Masaya|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 17383426
Journal: EMBO J. 2007 May 2;26(9):2284-94. Epub 2007 Apr 5.
Title: CBP/p300 are bimodal regulators of Wnt signaling.
Author: Li, Jiong|Sutter, Chris|Parker, David S|Blauwkamp, Timothy|Fang, Ming|Cadigan, Ken M
PMID: 17410209
Journal: J Mol Signal. 2007 Jul 16;2:6.
Title: Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling.
Author: Schepeler, Troels|Mansilla, Francisco|Christensen, Lise L|Orntoft, Torben F|Andersen, Claus L
PMID: 17634137
Journal: Nat Genet. 2007 Nov;39(11):1376-83. Epub 2007 Sep 30.
Title: EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.
Author: Cortina, Carme|Palomo-Ponce, Sergio|Iglesias, Mar|Fernandez-Masip, Juan Luis|Vivancos, Ana|Whissell, Gavin|Huma, Mireia|Peiro, Nerea|Gallego, Lourdes|Jonkheer, Suzanne|Davy, Alice|Lloreta, Josep|Sancho, Elena|Batlle, Eduard
PMID: 17906625
Journal: Oncogene. 2008 Mar 6;27(11):1527-35. Epub 2007 Sep 10.
Title: Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both beta-catenin/Tcf and AP-1-dependent transcription in colon carcinoma cells.
Author: Wang, Q|Sun, Z|Yang, H-S
PMID: 17828298
Journal: Mol Cell Biol. 2008 Apr;28(8):2732-44.
Title: Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.
Author: Hatzis, Pantelis|van der Flier, Laurens G|van Driel, Marc A|Guryev, Victor|Nielsen, Fiona|Denissov, Sergei|Nijman, Isaac J|Koster, Jan|Santo, Evan E|Welboren, Willem|Versteeg, Rogier|Cuppen, Edwin|van de Wetering, Marc|Clevers, Hans|Stunnenberg, Hendrik G
PMID: 18268006
Journal: Diabetes Care. 2008 May;31(5):905-9.
Title: Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study.
Author: Folsom, Aaron R|Pankow, James S|Peacock, James M|Bielinski, Suzette J|Heiss, Gerardo|Boerwinkle, Eric
PMID: 18268068
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Apr;17(4):978-82.
Title: Transcription factor 7-like 2 polymorphism and colon cancer.
Author: Slattery, Martha L|Folsom, Aaron R|Wolff, Roger|Herrick, Jenifer|Caan, Bette J|Potter, John D
PMID: 18398040
Journal: Gastroenterology. 2008 Jun;134(7):1961-71, 1971.e1-4.
Title: Regulation of Wnt signaling by the nuclear pore complex.
Author: Shitashige, Miki|Satow, Reiko|Honda, Kazufumi|Ono, Masaya|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 18439914
Journal: Cancer Causes Control. 2008 Nov;19(9):975-80.
Title: Association of the TCF7L2 polymorphism with colorectal cancer and adenoma risk.
Author: Hazra, Aditi|Fuchs, Charles S|Chan, Andrew T|Giovannucci, Edward L|Hunter, David J
PMID: 18478343
Journal: Biochim Biophys Acta. 2008 Dec;1782(12):800-8.
Title: The ubiquitin-proteasome system in colorectal cancer.
Author: Voutsadakis, Ioannis A
PMID: 18619533
Journal: Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9697-702.
Title: A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer.
Author: Tang, Wei|Dodge, Michael|Gundapaneni, Deepika|Michnoff, Carolyn|Roth, Michael|Lum, Lawrence
PMID: 18621708
Journal: Mol Cell Biol. 2008 Dec;28(24):7368-79.
Title: A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression.
Author: Yochum, Gregory S|Cleland, Ryan|Goodman, Richard H
PMID: 18852287
Journal: Exp Cell Res. 2008 Dec 10;314(20):3712-23.
Title: KLF4 regulation in intestinal epithelial cell maturation.
Author: Flandez, M|Guilmeau, S|Blache, P|Augenlicht, L H
PMID: 18977346
Journal: Biochem Biophys Res Commun. 2008 Dec 26;377(4):1185-90.
Title: Celecoxib-induced degradation of T-cell factors-1 and -4 in human colon cancer cells.
Author: Takahashi-Yanaga, Fumi|Yoshihara, Tatsuya|Jingushi, Kentaro|Miwa, Yoshikazu|Morimoto, Sachio|Hirata, Masato|Sasaguri, Toshiyuki
PMID: 18983819
Journal: BMC Cancer. 2008 Nov 8;8:328.
Title: Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors.
Author: Takeda, Kayoko|Kinoshita, Ichiro|Shimizu, Yasushi|Ohba, Yusuke|Itoh, Tomoo|Matsuno, Yoshihiro|Shichinohe, Toshiaki|Dosaka-Akita, Hirotoshi
PMID: 18992165
Journal: J Pharmacol Sci. 2008 Dec;108(4):535-44. Epub 2008 Dec 10.
Title: Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine.
Author: Fujisawa, Toshio|Sugiyama, Michiko|Tomimoto, Ayako|Wada, Koichiro|Endo, Hiroki|Takahashi, Hirokazu|Yoneda, Kyoko|Yoneda, Masato|Inamori, Masahiko|Saito, Satoru|Terauchi, Yasuo|Kadowaki, Takashi|Tsuchiya, Naoto|Nakagama, Hitoshi|Nakajima, Atsushi
PMID: 19075513
Journal: Gastroenterology. 2009 Jan;136(1):196-205.e2.
Title: p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors.
Author: Wassermann, Stella|Scheel, Silvio K|Hiendlmeyer, Elke|Palmqvist, Richard|Horst, David|Hlubek, Falk|Haynl, Angela|Kriegl, Lydia|Reu, Simone|Merkel, Susanne|Brabletz, Thomas|Kirchner, Thomas|Jung, Andreas
PMID: 18951899
Journal: Mutat Res. 2009 Jan 15;660(1-2):12-21.
Title: Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.
Author: Slattery, Martha L|Wolff, Roger K|Curtin, Karen|Fitzpatrick, Frank|Herrick, Jennifer|Potter, John D|Caan, Bette J|Samowitz, Wade S
PMID: 18992263
Journal: Carcinogenesis. 2009 Feb;30(2):300-7.
Title: A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways.
Author: Suh, Yewseok|Afaq, Farrukh|Johnson, Jeremy J|Mukhtar, Hasan
PMID: 19037088
Journal: Gene. 2009 Mar 1;432(1-2):112-7.
Title: The Bcl-w promoter is activated by beta-catenin/TCF4 in human colorectal carcinoma cells.
Author: Lapham, Abigail|Adams, Jemimah E|Paterson, Alex|Lee, Melanie|Brimmell, Matthew|Packham, Graham
PMID: 19124064
Journal: Cancer Res. 2009 Feb 15;69(4):1343-9.
Title: Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity.
Author: Song, Shumei|Mazurek, Nachman|Liu, Chunming|Sun, Yunjie|Ding, Qing Qing|Liu, Kaifeng|Hung, Mien-Chie|Bresalier, Robert S
PMID: 19190323
Journal: Int J Colorectal Dis. 2009 Aug;24(8):875-84.
Title: Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer.
Author: Fang, Y J|Lu, Z H|Wang, G Q|Pan, Z Z|Zhou, Z W|Yun, J P|Zhang, M F|Wan, D S
PMID: 19421758
Journal: J Biol Chem. 2009 Jul 17;284(29):19613-22.
Title: MAD2B, a novel TCF4-binding protein, modulates TCF4-mediated epithelial-mesenchymal transdifferentiation.
Author: Hong, Chun-Fu|Chou, Yu-Ting|Lin, Young-Sun|Wu, Cheng-Wen
PMID: 19443654
Journal: Nat Genet. 2009 Aug;41(8):885-90.
Title: The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.
Author: Tuupanen, Sari|Turunen, Mikko|Lehtonen, Rainer|Hallikas, Outi|Vanharanta, Sakari|Kivioja, Teemu|Bjorklund, Mikael|Wei, Gonghong|Yan, Jian|Niittymaki, Iina|Mecklin, Jukka-Pekka|Jarvinen, Heikki|Ristimaki, Ari|Di-Bernardo, Mariachiara|East, Phil|Carvajal-Ca
PMID: 19561604
Journal: Nat Genet. 2009 Aug;41(8):882-4.
Title: The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Author: Pomerantz, Mark M|Ahmadiyeh, Nasim|Jia, Li|Herman, Paula|Verzi, Michael P|Doddapaneni, Harshavardhan|Beckwith, Christine A|Chan, Jennifer A|Hills, Adam|Davis, Matt|Yao, Keluo|Kehoe, Sarah M|Lenz, Heinz-Josef|Haiman, Christopher A|Yan, Chunli|Henderson, Br
PMID: 19561607
Journal: Hum Mol Genet. 2009 Oct 1;18(19):3696-707.
Title: Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.
Author: Goncalves, Vania|Matos, Paulo|Jordan, Peter
PMID: 19602482
Journal: J Pathol. 2009 Sep;219(1):103-13.
Title: c-Rel is a transcriptional repressor of EPHB2 in colorectal cancer.
Author: Fu, Tao|Li, Peng|Wang, Hanzhi|He, Yujun|Luo, Donglin|Zhang, Anping|Tong, Weidong|Zhang, Lianyang|Liu, Baohua|Hu, Chuanmin
PMID: 19621336
Journal: Cancer Causes Control. 2009 Nov;20(9):1739-51.
Title: Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer.
Author: Tsilidis, Konstantinos K|Helzlsouer, Kathy J|Smith, Michael W|Grinberg, Victoriya|Hoffman-Bolton, Judith|Clipp, Sandra L|Visvanathan, Kala|Platz, Elizabeth A
PMID: 19760027
Journal: EMBO J. 2009 Nov 4;28(21):3329-40.
Title: The kinase TNIK is an essential activator of Wnt target genes.
Author: Mahmoudi, Tokameh|Li, Vivian S W|Ng, Ser Sue|Taouatas, Nadia|Vries, Robert G J|Mohammed, Shabaz|Heck, Albert J|Clevers, Hans
PMID: 19816403
Journal: PLoS One. 2009 Nov 17;4(11):e7872.
Title: Control of TCF-4 expression by VDR and vitamin D in the mouse mammary gland and colorectal cancer cell lines.
Author: Beildeck, Marcy E|Islam, Md|Shah, Salimuddin|Welsh, Joellen|Byers, Stephen W
PMID: 19924301
Journal: Oncogene. 2010 Jan 7;29(1):128-38.
Title: Downregulation of E-cadherin is an essential event in activating beta-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells.
Author: Wang, Q|Sun, Z-X|Allgayer, H|Yang, H-S
PMID: 19784072
Journal: Curr Opin Gastroenterol. 2010 Jan;26(1):47-52.
Title: Recent insights into the pathogenesis of colorectal cancer.
Author: Goel, Ajay|Boland, Clement Richard
PMID: 19786869
Journal: Mol Cell Biol. 2010 Jan;30(2):372-81.
Title: KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin.
Author: Evans, Paul M|Chen, Xi|Zhang, Wen|Liu, Chunming
PMID: 19901072
Journal: Chem Commun (Camb). 2010 Jun 21;46(23):4021-42.
Title: Total synthesis of (+)-A83586C, (+)-kettapeptin and (+)-azinothricin: powerful new inhibitors of beta-catenin/TCF4- and E2F-mediated gene transcription.
Author: Hale, Karl J|Manaviazar, Soraya|George, Jonathan
PMID: 20405066
Journal: Int J Oncol. 2010 Jun;36(6):1573-80.
Title: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells.
Author: Wang, Xize|Chen, Wei|Singh, Navneet|Promkan, Multira|Liu, Guangming
PMID: 20428782
Journal: Neoplasia. 2010 May;12(5):415-24.
Title: Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
Author: Kaur, Manjinder|Velmurugan, Balaiya|Tyagi, Alpna|Agarwal, Chapla|Singh, Rana P|Agarwal, Rajesh
PMID: 20454513
Journal: Mol Cancer. 2010 May 11;9:104.
Title: The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors.
Author: Sturgill, Thomas W|Stoddard, Paul B|Cohn, Steven M|Mayo, Marty W
PMID: 20459822
Journal: Nucleic Acids Res. 2010 Sep;38(17):5735-45.
Title: Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq.
Author: Bottomly, Daniel|Kyler, Sydney L|McWeeney, Shannon K|Yochum, Gregory S
PMID: 20460455
Journal: Cancer Res. 2010 Jun 15;70(12):5024-33.
Title: Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth.
Author: Shitashige, Miki|Satow, Reiko|Jigami, Takafumi|Aoki, Kazunori|Honda, Kazufumi|Shibata, Tatsuhiro|Ono, Masaya|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 20530691
Journal: J Biol Chem. 2010 Aug 20;285(34):26289-94.
Title: Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation.
Author: Satow, Reiko|Shitashige, Miki|Jigami, Takafumi|Honda, Kazufumi|Ono, Masaya|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 20566648
Journal: Diabetologia. 2010 Nov;53(11):2340-6.
Title: Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo.
Author: Zhao, J|Schug, J|Li, M|Kaestner, K H|Grant, S F A
PMID: 20640398
Journal: Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15157-62.
Title: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Author: Verzi, Michael P|Hatzis, Pantelis|Sulahian, Rita|Philips, Juliet|Schuijers, Jurian|Shin, Hyunjin|Freed, Ellen|Lynch, John P|Dang, Duyen T|Brown, Myles|Clevers, Hans|Liu, X Shirley|Shivdasani, Ramesh A
PMID: 20696899
Journal: Acta Biochim Biophys Sin (Shanghai). 2010 Jul;42(7):450-6.
Title: NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer.
Author: Guo, Qin|Shen, Shourong|Liao, Mantian|Lian, Ping|Wang, Xiaoyan
PMID: 20705583
Journal: PLoS One. 2010 Aug 12;5(8):e12109.
Title: Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells.
Author: Kang, Dong Woo|Min, Do Sik
PMID: 20711340
Journal: J Transl Med. 2010 Nov 22;8:123.
Title: LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer.
Author: Kriegl, Lydia|Horst, David|Reiche, Jana A|Engel, Jutta|Kirchner, Thomas|Jung, Andreas
PMID: 21092222
Journal: PLoS Biol. 2010 Nov 16;8(11):e1000539.
Title: The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis.
Author: Mahmoudi, Tokameh|Boj, Sylvia F|Hatzis, Pantelis|Li, Vivian S W|Taouatas, Nadia|Vries, Robert G J|Teunissen, Hans|Begthel, Harry|Korving, Jeroen|Mohammed, Shabaz|Heck, Albert J R|Clevers, Hans
PMID: 21103407
Journal: Int J Cancer. 2011 Mar 15;128(6):1280-92.
Title: beta-Catenin and NF-kappaB cooperate to regulate the uPA/uPAR system in cancer cells.
Author: Moreau, Marie|Mourah, Samia|Dosquet, Christine
PMID: 20473943
Journal: Mol Cell Proteomics. 2011 Jan;10(1):M110.002998.
Title: Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway.
Author: Thorsen, Kasper|Mansilla, Francisco|Schepeler, Troels|Oster, Bodil|Rasmussen, Mads H|Dyrskjot, Lars|Karni, Rotem|Akerman, Martin|Krainer, Adrian R|Laurberg, Soren|Andersen, Claus L|Orntoft, Torben F
PMID: 20938052
Journal: Cell Res. 2011 May;21(5):730-40.
Title: A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis.
Author: Wang, Wei|Liu, Haiyang|Wang, Sheng|Hao, Xiaojiang|Li, Lin
PMID: 21321609
Journal: Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4914-9.
Title: T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis.
Author: Angus-Hill, Melinda L|Elbert, Kathryn M|Hidalgo, Julio|Capecchi, Mario R
PMID: 21383188
Journal: Physiol Genomics. 2011 May 1;43(10):640-54.
Title: Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet.
Author: Shah, Manasvi S|Schwartz, Scott L|Zhao, Chen|Davidson, Laurie A|Zhou, Beiyan|Lupton, Joanne R|Ivanov, Ivan|Chapkin, Robert S
PMID: 21406606
Journal: Pathology. 2011 Apr;43(3):220-7.
Title: A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors.
Author: Ernst, Aurelie|Aigner, Maximilian|Nakata, Susumu|Engel, Felix|Schlotter, Magdalena|Kloor, Matthias|Brand, Karsten|Schmitt, Steffen|Steinert, Gunnar|Rahbari, Nuh|Koch, Moritz|Radlwimmer, Bernhard|Weitz, Jurgen|Lichter, Peter
PMID: 21436631
Journal: J Biol Chem. 2011 May 27;286(21):19170-7.
Title: Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4).
Author: Togi, Sumihito|Ikeda, Osamu|Kamitani, Shinya|Nakasuji, Misa|Sekine, Yuichi|Muromoto, Ryuta|Nanbo, Asuka|Oritani, Kenji|Kawai, Taro|Akira, Shizuo|Matsuda, Tadashi
PMID: 21454679
Journal: Exp Cell Res. 2011 Jun 10;317(10):1368-81.
Title: The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways.
Author: Bordonaro, Michael|Tewari, Shruti|Atamna, Wafa|Lazarova, Darina L
PMID: 21473864
Journal: BMC Cancer. 2011 Jun 13;11:238.
Title: COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status.
Author: Asting, Annika Gustafsson|Caren, Helena|Andersson, Marianne|Lonnroth, Christina|Lagerstedt, Kristina|Lundholm, Kent
PMID: 21668942
Journal: Nat Genet. 2011 Sep 4;43(10):964-8.
Title: Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
Author: Bass, Adam J|Lawrence, Michael S|Brace, Lear E|Ramos, Alex H|Drier, Yotam|Cibulskis, Kristian|Sougnez, Carrie|Voet, Douglas|Saksena, Gordon|Sivachenko, Andrey|Jing, Rui|Parkin, Melissa|Pugh, Trevor|Verhaak, Roel G|Stransky, Nicolas|Boutin, Adam T|Barretin
PMID: 21892161
Journal: Carcinogenesis. 2011 Dec;32(12):1824-31.
Title: Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.
Author: Kendziorra, Emil|Ahlborn, Kerstin|Spitzner, Melanie|Rave-Frank, Margret|Emons, Georg|Gaedcke, Jochen|Kramer, Frank|Wolff, Hendrik A|Becker, Heinz|Beissbarth, Tim|Ebner, Reinhard|Ghadimi, B Michael|Pukrop, Tobias|Ried, Thomas|Grade, Marian
PMID: 21983179
Journal: Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19204-9.
Title: beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.
Author: Sanchez-Tillo, Ester|de Barrios, Oriol|Siles, Laura|Cuatrecasas, Miriam|Castells, Antoni|Postigo, Antonio
PMID: 22080605
Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Dec;33(6):654-8.
Title: [Effects of sodium selenite on the expressions of beta-catenin and its target cyclin D1 in colorectal cancer cells HCT 116 and SW480].
Author: Luo, Hui|Yang, Yang|Xu, Cai-Min
PMID: 22509550
Journal: Gut. 2012 May;61(5):714-24.
Title: The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling.
Author: Chen, Hang-Zi|Liu, Qing-Feng|Li, Li|Wang, Wei-Jia|Yao, Lu-Ming|Yang, Meng|Liu, Bo|Chen, Wei|Zhan, Yan-Yan|Zhang, Ming-Qing|Cai, Jian-Chun|Zheng, Zhong-hui|Lin, Sheng-Cai|Li, Bo-An|Wu, Qiao
PMID: 21873734
Journal: Int J Oncol. 2012 Feb;40(2):519-26.
Title: Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer.
Author: Lan, Fengming|Yue, Xiao|Han, Lei|Shi, Zhendong|Yang, Yang|Pu, Peiyu|Yao, Zhi|Kang, Chunsheng
PMID: 21956205
Journal: Oncogene. 2012 May 31;31(22):2750-60.
Title: Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes.
Author: Schepeler, T|Holm, A|Halvey, P|Nordentoft, I|Lamy, P|Riising, E M|Christensen, L L|Thorsen, K|Liebler, D C|Helin, K|Orntoft, T F|Andersen, C L
PMID: 21963845
Journal: Biochem Pharmacol. 2012 Jan 1;83(1):47-56.
Title: DIF-1 inhibits the Wnt/beta-catenin signaling pathway by inhibiting TCF7L2 expression in colon cancer cell lines.
Author: Jingushi, Kentaro|Takahashi-Yanaga, Fumi|Yoshihara, Tatsuya|Shiraishi, Fumie|Watanabe, Yutaka|Hirata, Masato|Morimoto, Sachio|Sasaguri, Toshiyuki
PMID: 22005519
Journal: Gut. 2012 Sep;61(9):1306-14.
Title: beta-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.
Author: Smartt, Helena J M|Greenhough, Alexander|Ordonez-Moran, Paloma|Talero, Elena|Cherry, Catherine A|Wallam, Catherine A|Parry, Lee|Al Kharusi, Manal|Roberts, Heather R|Mariadason, John M|Clarke, Alan R|Huelsken, Joerg|Williams, Ann C|Paraskeva, Chris
PMID: 22082586
Journal: Cancer Lett. 2012 Apr 1;317(1):65-71.
Title: P-21 activated kinase 1 knockdown inhibits beta-catenin signalling and blocks colorectal cancer growth.
Author: He, Hong|Huynh, Nhi|Liu, Kevin H|Malcontenti-Wilson, Cathy|Zhu, Jin|Christophi, Christopher|Shulkes, Arthur|Baldwin, Graham S
PMID: 22100495
Journal: Mol Endocrinol. 2012 Jan;26(1):37-51.
Title: VDR/RXR and TCF4/beta-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression.
Author: Meyer, Mark B|Goetsch, Paul D|Pike, J Wesley
PMID: 22108803
Journal: Gastroenterology. 2012 Mar;142(3):572-81.
Title: beta-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.
Author: Satow, Reiko|Shitashige, Miki|Jigami, Takafumi|Fukami, Kiyoko|Honda, Kazufumi|Kitabayashi, Issay|Yamada, Tesshi
PMID: 22155184
Journal: Biochemistry. 2012 Jan 17;51(2):724-31.
Title: Structure-based discovery of a novel inhibitor targeting the beta-catenin/Tcf4 interaction.
Author: Tian, Wang|Han, Xiaofeng|Yan, Maocai|Xu, Yan|Duggineni, Srinivas|Lin, Nan|Luo, Guifen|Li, Yan Michael|Han, Xiaobing|Huang, Ziwei|An, Jing
PMID: 22224445
Journal: J Med Chem. 2012 Feb 9;55(3):1346-59.
Title: Design, synthesis, and biological evaluation of new diaminoquinazolines as beta-catenin/Tcf4 pathway inhibitors.
Author: Mao, Yongjun|Lin, Nan|Tian, Wang|Han, Xiaofeng|Han, Xiaobing|Huang, Ziwei|An, Jing
PMID: 22229647
Journal: J Clin Endocrinol Metab. 2012 May;97(5):E845-51.
Title: Effect of type 2 diabetes predisposing genetic variants on colorectal cancer risk.
Author: Sainz, Juan|Rudolph, Anja|Hoffmeister, Michael|Frank, Bernd|Brenner, Hermann|Chang-Claude, Jenny|Hemminki, Kari|Forsti, Asta
PMID: 22419714
Journal: Cancer Genet. 2012 Jan-Feb;205(1-2):25-33.
Title: Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583.
Author: Tuupanen, Sari|Yan, Jian|Turunen, Mikko|Gylfe, Alexandra E|Kaasinen, Eevi|Li, Li|Eng, Charis|Culver, Daniel A|Kalady, Matthew F|Pennison, Michael J|Pasche, Boris|Manne, Upender|de la Chapelle, Albert|Hampel, Heather|Henderson, Brian E|Le Marchand, Loic|Ha
PMID: 22429595
Journal: Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41.
Title: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.
Author: Yeh, Chi-Tai|Rao, Yerra Koteswara|Ye, Min|Wu, Wen-Shi|Chang, Tung-Chen|Wang, Liang-Shun|Wu, Chih-Hsiung|Wu, Alexander T H|Tzeng, Yew-Min
PMID: 22465936
Journal: Cold Spring Harb Perspect Biol. 2012 Apr 1;4(4):a007989.
Title: Wnt signaling, stem cells, and cancer of the gastrointestinal tract.
Author: Schepers, Arnout|Clevers, Hans
PMID: 22474007
Journal: EMBO J. 2012 Jun 13;31(12):2685-96.
Title: Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins.
Author: Schuijers, Jurian|Clevers, Hans
PMID: 22617424
Journal: Cancer Res. 2012 Jul 15;72(14):3607-17.
Title: Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism.
Author: Lee, Su Yeon|Jeon, Hyun Min|Ju, Min Kyung|Kim, Cho Hee|Yoon, Gyesoon|Han, Song Iy|Park, Hye Gyeong|Kang, Ho Sung
PMID: 22637725
Journal: Stem Cells. 2012 Oct;30(10):2076-87.
Title: Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms.
Author: Ibrahim, Elsayed E|Babaei-Jadidi, Roya|Saadeddin, Anas|Spencer-Dene, Bradley|Hossaini, Sina|Abuzinadah, Mohammed|Li, Ningning|Fadhil, Wakkas|Ilyas, Mohammad|Bonnet, Dominique|Nateri, Abdolrahman S
PMID: 22851508
Journal: Nature. 2012 Aug 30;488(7413):660-4.
Title: Recurrent R-spondin fusions in colon cancer.
Author: Seshagiri, Somasekar|Stawiski, Eric W|Durinck, Steffen|Modrusan, Zora|Storm, Elaine E|Conboy, Caitlin B|Chaudhuri, Subhra|Guan, Yinghui|Janakiraman, Vasantharajan|Jaiswal, Bijay S|Guillory, Joseph|Ha, Connie|Dijkgraaf, Gerrit J P|Stinson, Jeremy|Gnad, Flo
PMID: 22895193
Journal: Biochem Pharmacol. 2012 Nov 1;84(9):1143-53.
Title: The beta-catenin/TCF complex as a novel target of resveratrol in the Wnt/beta-catenin signaling pathway.
Author: Chen, Hui-Jye|Hsu, Le-Shiang|Shia, Yu-Ting|Lin, Meng-Wei|Lin, Chung-Ming
PMID: 22935447
Journal: PLoS One. 2012;7(9):e45462.
Title: Activating mutations in beta-catenin in colon cancer cells alter their interaction with macrophages; the role of snail.
Author: Kaler, Pawan|Augenlicht, Leonard|Klampfer, Lidija
PMID: 23029025
Journal: PLoS One. 2012;7(12):e51205.
Title: Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.
Author: Barrett, Caitlyn W|Smith, J Joshua|Lu, Lauren C|Markham, Nicholas|Stengel, Kristy R|Short, Sarah P|Zhang, Baolin|Hunt, Aubrey A|Fingleton, Barbara M|Carnahan, Robert H|Engel, Michael E|Chen, Xi|Beauchamp, R Daniel|Wilson, Keith T|Hiebert, Scott W|Reynolds
PMID: 23251453
Journal: Nutr Metab Cardiovasc Dis. 2013 Jun;23(6):550-6.
Title: Functional analysis of TCF7L2 genetic variants associated with type 2 diabetes.
Author: Pang, D X|Smith, A J P|Humphries, S E
PMID: 22402060
Journal: Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.
Title: Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Author: Ho, Koc-Kan|Parnell, K Mark|Yuan, Yi|Xu, Yong|Kultgen, Steven G|Hamblin, Steven|Hendrickson, Thomas F|Luo, Bai|Foulks, Jason M|McCullar, Michael V|Kanner, Steven B
PMID: 23232060
Journal: Cancer Res. 2013 Mar 15;73(6):2003-13.
Title: Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/beta-catenin pathway in colorectal cancer.
Author: Camps, Jordi|Pitt, Jason J|Emons, Georg|Hummon, Amanda B|Case, Chanelle M|Grade, Marian|Jones, Tamara L|Nguyen, Quang T|Ghadimi, B Michael|Beissbarth, Tim|Difilippantonio, Michael J|Caplen, Natasha J|Ried, Thomas
PMID: 23319804
Journal: Clin Cancer Res. 2013 Mar 1;19(5):1071-82.
Title: ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.
Author: Sanchez-Tillo, Ester|de Barrios, Oriol|Siles, Laura|Amendola, Pier G|Darling, Douglas S|Cuatrecasas, Miriam|Castells, Antoni|Postigo, Antonio
PMID: 23340304
Journal: J Cancer. 2013;4(2):96-103.
Title: Crosstalk between Wnt Signaling and RNA Processing in Colorectal Cancer.
Author: Bordonaro, Michael
PMID: 23386908
Journal: J Vis Exp. 2013 Apr 19;(74).
Title: Generation of high quality chromatin immunoprecipitation DNA template for high-throughput sequencing (ChIP-seq).
Author: Deliard, Sandra|Zhao, Jianhua|Xia, Qianghua|Grant, Struan F A
PMID: 23629434
Journal: Dig Dis Sci. 2013 Sep;58(9):2507-17.
Title: Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis.
Author: Sadik, Nermin Abdel Hamid|Shaker, Olfat Gamil
PMID: 23722564
Journal: Genome Res. 2013 Sep;23(9):1446-61.
Title: CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer.
Author: Ling, Hui|Spizzo, Riccardo|Atlasi, Yaser|Nicoloso, Milena|Shimizu, Masayoshi|Redis, Roxana S|Nishida, Naohiro|Gafa, Roberta|Song, Jian|Guo, Zhiyi|Ivan, Cristina|Barbarotto, Elisa|De Vries, Ingrid|Zhang, Xinna|Ferracin, Manuela|Churchman, Mike|van Galen, J
PMID: 23796952
Journal: Carcinogenesis. 2013 Dec;34(12):2861-9.
Title: GPR48, a poor prognostic factor, promotes tumor metastasis and activates beta-catenin/TCF signaling in colorectal cancer.
Author: Wu, Jinhua|Xie, Na|Xie, Ke|Zeng, Jun|Cheng, Lin|Lei, Yunlong|Liu, Yuan|Song, Linhong|Dong, Dandan|Chen, Yi|Zeng, Rui|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 23803691
Journal: PLoS One. 2013 Jul 2;8(7):e68525.
Title: Henryin, an ent-kaurane diterpenoid, inhibits Wnt signaling through interference with beta-catenin/TCF4 interaction in colorectal cancer cells.
Author: Li, Xingyao|Pu, Jianxin|Jiang, Shiyou|Su, Jia|Kong, Lingmei|Mao, Bingyu|Sun, Handong|Li, Yan
PMID: 23844215
Journal: PLoS One. 2013 Aug 9;8(8):e71730.
Title: Association between TCF7L2 gene polymorphism and cancer risk: a meta-analysis.
Author: Chen, Jingxiang|Yuan, Tao|Liu, Menggang|Chen, Ping
PMID: 23951231
Journal: J Natl Cancer Inst. 2013 Dec 18;105(24):1852-61.
Title: Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations.
Author: Nan, Hongmei|Morikawa, Teppei|Suuriniemi, Miia|Imamura, Yu|Werner, Lillian|Kuchiba, Aya|Yamauchi, Mai|Hunter, David J|Kraft, Peter|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji|Freedman, Matthew L|Chan, Andrew T
PMID: 24317174
Journal: Int J Med Sci. 2013 Nov 25;10(13):1888-98.
Title: Modulation of beta-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways.
Author: Zhang, Wenwen|Zhang, Hongyu|Wang, Ning|Zhao, Chen|Zhang, Hongmei|Deng, Fang|Wu, Ningning|He, Yunfeng|Chen, Xian|Zhang, Junhui|Wen, Sheng|Liao, Zhan|Zhang, Qian|Zhang, Zhonglin|Liu, Wei|Yan, Zhengjian|Luu, Hue H|Haydon, Rex C|Zhou, Lan|He, Tong-Chuan
PMID: 24324366
Journal: Genet Mol Res. 2013 Dec 4;12(4):6268-74.
Title: Colorectal cancer susceptibility variants alter risk of breast cancer in a Chinese Han population.
Author: Wei, W|Jiang, M|Luo, L|Li, Z|Wang, P|Dong, W Q
PMID: 24338422
Journal: Pharmacogenomics J. 2014 Apr;14(2):142-50.
Title: Association of common gene variants in the WNT/beta-catenin pathway with colon cancer recurrence.
Author: Paez, D|Gerger, A|Zhang, W|Yang, D|Labonte, M J|Benhanim, L|Kahn, M|Lenz, F|Lenz, C|Ning, Y|Wakatsuki, T|Loupakis, F|Lenz, H-J
PMID: 23817222
Journal: Oncogene. 2014 Aug 7;33(32):4156-63.
Title: EIF3i promotes colon oncogenesis by regulating COX-2 protein synthesis and beta-catenin activation.
Author: Qi, J|Dong, Z|Liu, J|Zhang, J-T
PMID: 24056964
Journal: Carcinogenesis. 2014 May;35(5):1092-9.
Title: Regulation of TRAIL receptor expression by beta-catenin in colorectal tumours.
Author: Jalving, M|Heijink, D M|Koornstra, J J|Boersma-van Ek, W|Zwart, N|Wesseling, J|Sluiter, W J|de Vries, E G E|Kleibeuker, J H|de Jong, S
PMID: 24379239
Journal: Int J Mol Med. 2014 Mar;33(3):581-8.
Title: Revealing the molecular mechanism of colorectal cancer by establishing LGALS3-related protein-protein interaction network and identifying signaling pathways.
Author: Han, Lu|Wu, Zhixiong|Zhao, Qicheng
PMID: 24398765
Journal: EMBO J. 2014 Jan 13;33(2):146-56.
Title: Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.
Author: Schuijers, Jurian|Mokry, Michal|Hatzis, Pantelis|Cuppen, Edwin|Clevers, Hans
PMID: 24413017
Journal: PLoS One. 2014 Jan 22;9(1):e86582.
Title: Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.
Author: Takahashi, Norihiko|Yamaguchi, Kiyoshi|Ikenoue, Tsuneo|Fujii, Tomoaki|Furukawa, Yoichi
PMID: 24466159
Journal: Clin Cancer Res. 2014 Mar 15;20(6):1687-97.
Title: A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.
Author: Szkandera, Joanna|Pichler, Martin|Absenger, Gudrun|Stotz, Michael|Weissmueller, Melanie|Samonigg, Hellmut|Asslaber, Martin|Lax, Sigurd|Leitner, Gerhard|Winder, Thomas|Renner, Wilfried|Gerger, Armin
PMID: 24470513
Journal: Int J Oncol. 2014 Apr;44(4):1341-8.
Title: Stimulation of beta-catenin and colon cancer cell growth by the KDM4B histone demethylase.
Author: Berry, William L|Kim, Tae-Dong|Janknecht, Ralf
PMID: 24481461
Journal: J Biol Chem. 2014 Mar 28;289(13):8881-90.
Title: Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer.
Author: Xu, Xuehe|Yu, Tianxin|Shi, Jiandang|Chen, Xi|Zhang, Wen|Lin, Ting|Liu, Zhihong|Wang, Yadong|Zeng, Zheng|Wang, Chi|Li, Mingsong|Liu, Chunming
PMID: 24532795
Journal: PLoS One. 2014 Mar 7;9(3):e91264.
Title: High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: novel fusion partner and splice variants.
Author: Nome, Torfinn|Hoff, Andreas M|Bakken, Anne Cathrine|Rognum, Torleiv O|Nesbakken, Arild|Skotheim, Rolf I
PMID: 24608966
Journal: Biochem Pharmacol. 2014 Jun 1;89(3):340-8.
Title: DIF-1 inhibits tumor growth in vivo reducing phosphorylation of GSK-3beta and expressions of cyclin D1 and TCF7L2 in cancer model mice.
Author: Takahashi-Yanaga, Fumi|Yoshihara, Tatsuya|Jingushi, Kentaro|Igawa, Kazuhiro|Tomooka, Katsuhiko|Watanabe, Yutaka|Morimoto, Sachio|Nakatsu, Yoshimichi|Tsuzuki, Teruhisa|Nakabeppu, Yusaku|Sasaguri, Toshiyuki
PMID: 24670930
Journal: BMC Res Notes. 2014 Apr 9;7:226.
Title: Butyrate induced changes in Wnt-signaling specific gene expression in colorectal cancer cells.
Author: Lazarova, Darina L|Chiaro, Christopher|Bordonaro, Michael
PMID: 24716727
Journal: J Nat Prod. 2014 May 23;77(5):1130-4.
Title: Plumbagin downregulates Wnt signaling independent of p53 in human colorectal cancer cells.
Author: Raghu, Dinesh|Karunagaran, Devarajan
PMID: 24828199
Journal: Nat Genet. 2014 Jun;46(6):533-42.
Title: Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Author: Zhang, Ben|Jia, Wei-Hua|Matsuda, Koichi|Kweon, Sun-Seog|Matsuo, Keitaro|Xiang, Yong-Bing|Shin, Aesun|Jee, Sun Ha|Kim, Dong-Hyun|Cai, Qiuyin|Long, Jirong|Shi, Jiajun|Wen, Wanqing|Yang, Gong|Zhang, Yanfeng|Li, Chun|Li, Bingshan|Guo, Yan|Ren, Zefang|Ji, Bu-T
PMID: 24836286
Journal: Gastroenterology. 2014 Aug;147(2):430-442.e8.
Title: ITF2 prevents activation of the beta-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.
Author: Shin, Hyun-Woo|Choi, Hyunsung|So, Daeho|Kim, Young-Im|Cho, Kumsun|Chung, Hee-Joon|Lee, Kyoung-Hwa|Chun, Yang-Sook|Cho, Chung-Hyun|Kang, Gyeong Hoon|Kim, Woo Ho|Park, Jong-Wan
PMID: 24846398
Journal: Anticancer Drugs. 2014 Sep;25(8):908-16.
Title: TCF4 silencing sensitizes the colon cancer cell line to oxaliplatin as a common chemotherapeutic drug.
Author: Gheidari, Fatemeh|Bakhshandeh, Behnaz|Teimoori-Toolabi, Ladan|Mehrtash, Amirhosein|Ghadir, Mahdis|Zeinali, Sirous
PMID: 24869759
Journal: J Cell Biochem. 2014 Nov;115(11):1974-84.
Title: MiR-29b downregulates canonical Wnt signaling by suppressing coactivators of beta-catenin in human colorectal cancer cells.
Author: Subramanian, Maitreyi|Rao, Srinivasa R|Thacker, Pooja|Chatterjee, Suvro|Karunagaran, Devarajan
PMID: 24913975
Journal: BMC Med Genomics. 2014 Jun 18;7:36.
Title: Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer.
Author: Shanmugam, Vijayalakshmi|Ramanathan, Ramesh K|Lavender, Nicole A|Sinari, Shripad|Chadha, Manpreet|Liang, Winnie S|Kurdoglu, Ahmet|Izatt, Tyler|Christoforides, Alexis|Benson, Hollie|Phillips, Lori|Baker, Angela|Murray, Christopher|Hostetter, Galen|Von Hoff
PMID: 24943349
Journal: Tumour Biol. 2014 Oct;35(10):10319-24.
Title: Oncogenicity of LHX4 in colorectal cancer through Wnt/beta-catenin/TCF4 cascade.
Author: Cha, Nier|Liu, Wei|Yang, Na|Xie, Shengzhi|Gao, Yanwei|Chen, Xia|Wang, Xiaoli|Ren, Jun
PMID: 25034524
Journal: Int J Oncol. 2014 Oct;45(4):1715-23.
Title: Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells.
Author: Gotze, Silke|Coersmeyer, Monique|Muller, Oliver|Sievers, Sonja
PMID: 25050608
Journal: Cell Rep. 2014 Aug 21;8(4):983-90.
Title: A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.
Author: Lewis, Annabelle|Freeman-Mills, Luke|de la Calle-Mustienes, Elisa|Giraldez-Perez, Rosa Maria|Davis, Hayley|Jaeger, Emma|Becker, Martin|Hubner, Nina C|Nguyen, Luan N|Zeron-Medina, Jorge|Bond, Gareth|Stunnenberg, Hendrik G|Carvajal, Jaime J|Gomez-Skarmeta,
PMID: 25131200
Journal: Eur J Pharmacol. 2014 Nov 5;742:55-64.
Title: Emodin suppresses Wnt signaling in human colorectal cancer cells SW480 and SW620.
Author: Pooja, Thacker|Karunagaran, Devarajan
PMID: 25205133
Journal: BMJ Open Diabetes Res Care. 2014 Dec 1;2(1):e000052.
Title: Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data.
Author: Johnson, Matthew E|Zhao, Jianhua|Schug, Jonathan|Deliard, Sandra|Xia, Qianghua|Guy, Vanessa C|Sainz, Jesus|Kaestner, Klaus H|Wells, Andrew D|Grant, Struan F A
PMID: 25469308
Journal: Mol Carcinog. 2015 Sep;54(9):789-799.
Title: Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.
Author: Koneczny, Inga|Schulenburg, Axel|Hudec, Xenia|Knofler, Martin|Holzmann, Klaus|Piazza, Gary|Reynolds, Robert|Valent, Peter|Marian, Brigitte
PMID: 24619956
Journal: Mol Oncol. 2015 Feb;9(2):335-54.
Title: SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer.
Author: Ronsch, Kerstin|Jagle, Sabine|Rose, Katja|Seidl, Maximilian|Baumgartner, Francis|Freihen, Vivien|Yousaf, Afsheen|Metzger, Eric|Lassmann, Silke|Schule, Roland|Zeiser, Robert|Michoel, Tom|Hecht, Andreas
PMID: 25277775
Journal: Mol Cell Biochem. 2015 Jan;399(1-2):1-5.
Title: Lhx3 is required to maintain cancer cell development of high-grade oligodendroglioma.
Author: Liu, Hongliang|Liu, Wei|Zhu, Bin|Xu, Qiang|Ni, Xiaowei|Yu, Ji
PMID: 25399296
Journal: Oncogene. 2015 Sep 17;34(38):4914-27.
Title: Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer.
Author: Lemieux, E|Cagnol, S|Beaudry, K|Carrier, J|Rivard, N
PMID: 25500543
Journal: PLoS One. 2015 Jan 24;10(1):e0116753.
Title: A pathway-centric survey of somatic mutations in Chinese patients with colorectal carcinomas.
Author: Ling, Chao|Wang, Lin|Wang, Zheng|Xu, Luming|Sun, Lifang|Yang, Hui|Li, Wei-Dong|Wang, Kai
PMID: 25617745
Journal: Cell Cycle. 2015;14(3):323-32.
Title: A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells.
Author: Shah, Meera|Rennoll, Sherri A|Raup-Konsavage, Wesley M|Yochum, Gregory S
PMID: 25659031
Journal: Cell Signal. 2015 May;27(5):961-8.
Title: Kruppel-like factor 5 incorporates into the beta-catenin/TCF complex in response to LPA in colon cancer cells.
Author: Guo, Leilei|He, Peijian|No, Yi Ran|Yun, C Chris
PMID: 25683913
Journal: BMC Med Genet. 2015 Mar 24;16:18.
Title: Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.
Author: Thomas, Sushma S|Makar, Karen W|Li, Lin|Zheng, Yingye|Yang, Peiying|Levy, Lisa|Rudolph, Rebecca Yvonne|Lampe, Paul D|Yan, Min|Markowitz, Sanford D|Bigler, Jeannette|Lampe, Johanna W|Potter, John D
PMID: 25927723
Journal: Int J Mol Sci. 2015 May 7;16(5):10411-25.
Title: TCF4 Is a Molecular Target of Resveratrol in the Prevention of Colorectal Cancer.
Author: Jeong, Jin Boo|Lee, Jihye|Lee, Seong-Ho
PMID: 25961950
Journal: Cancer Res. 2015 Sep 1;75(17):3446-55.
Title: Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy.
Author: Maby, Pauline|Tougeron, David|Hamieh, Mohamad|Mlecnik, Bernhard|Kora, Hafid|Bindea, Gabriela|Angell, Helen K|Fredriksen, Tessa|Elie, Nicolas|Fauquembergue, Emilie|Drouet, Aurelie|Leprince, Jerome|Benichou, Jacques|Mauillon, Jacques|Le Pessot, Florence|Ses
PMID: 26060019
Journal: Oncogenesis. 2015 Jun 15;4:e157.
Title: An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/beta-catenin-elicited promotion of the cancer stem cell phenotype.
Author: Su, Y-J|Chang, Y-W|Lin, W-H|Liang, C-L|Lee, J-L
PMID: 26075748
Journal: Mol Cell Biol. 2015 Oct;35(20):3471-90.
Title: Differential Effects of Hepatocyte Nuclear Factor 4alpha Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.
Author: Vuong, Linh M|Chellappa, Karthikeyani|Dhahbi, Joseph M|Deans, Jonathan R|Fang, Bin|Bolotin, Eugene|Titova, Nina V|Hoverter, Nate P|Spindler, Stephen R|Waterman, Marian L|Sladek, Frances M
PMID: 26240283
Journal: Carcinogenesis. 2015 Oct;36(10):1103-10.
Title: Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer.
Author: Torabi, Keyvan|Miro, Rosa|Fernandez-Jimenez, Nora|Quintanilla, Isabel|Ramos, Laia|Prat, Esther|del Rey, Javier|Pujol, Nuria|Killian, J Keith|Meltzer, Paul S|Fernandez, Pedro Luis|Ried, Thomas|Lozano, Juan Jose|Camps, Jordi|Ponsa, Immaculada
PMID: 26243311
Journal: Oncotarget. 2015 Sep 29;6(29):28312-26.
Title: Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer.
Author: Heerma van Voss, Marise R|Vesuna, Farhad|Trumpi, Kari|Brilliant, Justin|Berlinicke, Cynthia|de Leng, Wendy|Kranenburg, Onno|Offerhaus, G Johan|Burger, Horst|van der Wall, Elsken|van Diest, Paul J|Raman, Venu
PMID: 26311743
Journal: Sci Signal. 2015 Sep 8;8(393):ra90.
Title: The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated beta-catenin by sequestering TCF4 to the nuclear membrane.
Author: Loregger, Anke|Grandl, Martina|Mejias-Luque, Raquel|Allgauer, Michael|Degenhart, Kathrin|Haselmann, Verena|Oikonomou, Christina|Hatzis, Pantelis|Janssen, Klaus-Peter|Nitsche, Ulrich|Gradl, Dietmar|van den Broek, Olaf|Destree, Olivier|Ulm, Kurt|Neumaier, M
PMID: 26350900
Journal: Oncogene. 2015 Nov 12;34(46):5760-70.
Title: ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression.
Author: Sanchez-Tillo, E|de Barrios, O|Valls, E|Darling, D S|Castells, A|Postigo, A
PMID: 26387539
Journal: Asian Pac J Cancer Prev. 2015;16(15):6549-56.
Title: Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways.
Author: Wee, Lee Heng|Morad, Noor Azian|Aan, Goon Jo|Makpol, Suzana|Wan Ngah, Wan Zurinah|Mohd Yusof, Yasmin Anum
PMID: 26434873
Journal: Sci Rep. 2015 Oct 8;5:14983.
Title: Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications.
Author: O'Connell, Malaney R|Sarkar, Shubhashish|Luthra, Gurinder K|Okugawa, Yoshinaga|Toiyama, Yuji|Gajjar, Aakash H|Qiu, Suimin|Goel, Ajay|Singh, Pomila
PMID: 26447334
Journal: Oncotarget. 2015 Nov 3;6(34):36587-602.
Title: Novel RNA variants in colorectal cancers.
Author: Hoff, Andreas M|Johannessen, Bjarne|Alagaratnam, Sharmini|Zhao, Sen|Nome, Torfinn|Lovf, Marthe|Bakken, Anne C|Hektoen, Merete|Sveen, Anita|Lothe, Ragnhild A|Skotheim, Rolf I
PMID: 26474385
Journal: Biochem Biophys Res Commun. 2015 Nov 27;467(4):629-37.
Title: Rock2 stabilizes beta-catenin to promote tumor invasion and metastasis in colorectal cancer.
Author: Qiu, Yumin|Yuan, Rongfa|Zhang, Shouhua|Chen, Leifeng|Huang, Da|Hao, Haibin|Shao, Jianghua
PMID: 26505794
Journal: Pharmacol Ther. 2015 Dec;156:1-9.
Title: Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer.
Author: Masuda, Mari|Sawa, Masaaki|Yamada, Tesshi
PMID: 26542362
Journal: Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Aug;32(4):854-61.
Title: [T Cell Factor 4, beta-catenin and SFRP1 Expression of Wnt Signaling Pathway in Colorectal Carcinoma and the Prognosis].
Author: Ou, Yurong|Jing, Guiying|Liu, Juan|Gao, Shan|Cheng, Zenong|Dong, Xiuqin
PMID: 26710459
Journal: J Steroid Biochem Mol Biol. 2016 Jan;155(Pt B):224-30.
Title: Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells.
Author: Groschel, Charlotte|Aggarwal, Abhishek|Tennakoon, Samawansha|Hobaus, Julia|Prinz-Wohlgenannt, Maximilian|Marian, Brigitte|Heffeter, Petra|Berger, Walter|Kallay, Eniko
PMID: 25777538
Journal: Gut. 2016 Oct;65(10):1690-701.
Title: New Wnt/beta-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Author: Qi, Jingjing|Yu, Yong|Akilli Ozturk, Ozlem|Holland, Jane D|Besser, Daniel|Fritzmann, Johannes|Wulf-Goldenberg, Annika|Eckert, Klaus|Fichtner, Iduna|Birchmeier, Walter
PMID: 26156959
Journal: Oncogene. 2016 Mar 31;35(13):1679-91.
Title: Wnt/beta-catenin signaling regulated SATB1 promotes colorectal cancer tumorigenesis and progression.
Author: Mir, R|Pradhan, S J|Patil, P|Mulherkar, R|Galande, S
PMID: 26165840
Journal: Gastroenterology. 2016 Mar;150(3):659-671.e16.
Title: OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.
Author: Ye, Guo-Dong|Sun, Guang-Bin|Jiao, Peng|Chen, Chen|Liu, Qing-Feng|Huang, Xiao-Li|Zhang, Rui|Cai, Wang-Yu|Li, Sheng-Nan|Wu, Jia-Fa|Liu, Yun-Jia|Wu, Rong-Si|Xie, Yuan-Yuan|Chan, Err-Cheng|Liou, Yih-Cherng|Li, Bo-An
PMID: 26619963
Journal: Oncogene. 2016 Sep 22;35(38):4990-9.
Title: Topoisomerase IIalpha mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.
Author: Zhou, Q|Abraham, A D|Li, L|Babalmorad, A|Bagby, S|Arcaroli, J J|Hansen, R J|Valeriote, F A|Gustafson, D L|Schaack, J|Messersmith, W A|LaBarbera, D V
PMID: 26947016
Journal: Cancer Cell Int. 2016 Mar 24;16:22.
Title: Time course analysis based on gene expression profile and identification of target molecules for colorectal cancer.
Author: Chen, Guoting|Han, Ning|Li, Guofeng|Li, Xin|Li, Guang|Li, Zengchun|Li, Qinchuan
PMID: 27013928
Journal: Cancer Prev Res (Phila). 2016 Jun;9(6):417-27.
Title: Genomic Landscape of Colorectal Mucosa and Adenomas.
Author: Borras, Ester|San Lucas, F Anthony|Chang, Kyle|Zhou, Ruoji|Masand, Gita|Fowler, Jerry|Mork, Maureen E|You, Y Nancy|Taggart, Melissa W|McAllister, Florencia|Jones, David A|Davies, Gareth E|Edelmann, Winfried|Ehli, Erik A|Lynch, Patrick M|Hawk, Ernest T|Cap
PMID: 27221540
Journal: Cell Rep. 2016 Jun 21;15(12):2588-96.
Title: A Positive Regulatory Loop between a Wnt-Regulated Non-coding RNA and ASCL2 Controls Intestinal Stem Cell Fate.
Author: Giakountis, Antonis|Moulos, Panagiotis|Zarkou, Vasiliki|Oikonomou, Christina|Harokopos, Vaggelis|Hatzigeorgiou, Artemis G|Reczko, Martin|Hatzis, Pantelis
PMID: 27292638
Journal: Nat Biotechnol. 2016 Aug;34(8):845-51.
Title: A recellularized human colon model identifies cancer driver genes.
Author: Chen, Huanhuan Joyce|Wei, Zhubo|Sun, Jian|Bhattacharya, Asmita|Savage, David J|Serda, Rita|Mackeyev, Yuri|Curley, Steven A|Bu, Pengcheng|Wang, Lihua|Chen, Shuibing|Cohen-Gould, Leona|Huang, Emina|Shen, Xiling|Lipkin, Steven M|Copeland, Neal G|Jenkins, Nan
PMID: 27398792
Journal: Biochim Biophys Acta. 2016 Nov;1859(11):1353-1367.
Title: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing.
Author: Schnappauf, Oskar|Beyes, Sven|Dertmann, Annika|Freihen, Vivien|Frey, Patrick|Jagle, Sabine|Rose, Katja|Michoel, Tom|Grosschedl, Rudolf|Hecht, Andreas
PMID: 27504909
Journal: Cancers (Basel). 2016 Aug 3;8(8). pii: cancers8080074.
Title: The Role of the C-Clamp in Wnt-Related Colorectal Cancers.
Author: Ravindranath, Aditi J|Cadigan, Ken M
PMID: 27527215
Journal: Cancer Sci. 2016 Dec;107(12):1776-1784.
Title: Wnt-beta-catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer.
Author: Kobayashi, Minoru|Funayama, Ryo|Ohnuma, Shinobu|Unno, Michiaki|Nakayama, Keiko
PMID: 27709738
Journal: Cell Mol Biol (Noisy-le-grand). 2016 Sep 30;62(11):13-20.
Title: TCF7L2 and CCND1 polymorphisms and its association with colorectal cancer in Mexican patients.
Author: Rosales-Reynoso, M A|Arredondo-Valdez, A R|Juarez-Vazquez, C I|Wence-Chavez, L I|Barros-Nunez, P|Gallegos-Arreola, M P|Flores-Martinez, S E|Moran-Moguel, M C|Sanchez-Corona, J
PMID: 27755946
Journal: Cancer Epidemiol. 2016 Dec;45:108-111.
Title: Association between the TCF7L2 polymorphism and colorectal cancer does not differ by diabetes and obesity statuses.
Author: Shim, Hyun-Jeong|Lee, Ran|Shin, Min-Ho|Kim, Hee-Nam|Kweon, Sun-Seog
PMID: 27792933
Journal: Mol Carcinog. 2017 Nov;56(11):2372-2381.
Title: Differential expression of LEF1/TCFs family members in colonic carcinogenesis.
Author: Han, Wenxiao|He, Longmei|Cao, Bangrong|Zhao, Xinhua|Zhang, Kaitai|Li, Yan|Beck, Paul|Zhou, Zhixiang|Tian, Yantao|Cheng, Shujun|Wang, Hongying
PMID: 27433921
Journal: Cancer Res. 2017 Jan 1;77(1):142-152.
Title: Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells.
Author: Kang, Dong Woo|Lee, Shin Wha|Hwang, Won Chan|Lee, Bo Hui|Choi, Yong-Seok|Suh, Young-Ah|Choi, Kang-Yell|Min, Do Sik
PMID: 27793841
Journal: Oncotarget. 2017 Jan 31;8(5):7852-7866.
Title: Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.
Author: Ashktorab, Hassan|Mokarram, Pooneh|Azimi, Hamed|Olumi, Hasti|Varma, Sudhir|Nickerson, Michael L|Brim, Hassan
PMID: 28002797
Journal: Oncotarget. 2017 Mar 14;8(11):18456-18485.
Title: 2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications.
Author: Gonzalez, Nieves|Prieto, Isabel|Del Puerto-Nevado, Laura|Portal-Nunez, Sergio|Ardura, Juan Antonio|Corton, Marta|Fernandez-Fernandez, Beatriz|Aguilera, Oscar|Gomez-Guerrero, Carmen|Mas, Sebastian|Moreno, Juan Antonio|Ruiz-Ortega, Marta|Sanz, Ana Belen|San
PMID: 28060743
Journal: Cancer Sci. 2017 Apr;108(4):612-619.
Title: Identification of FERM domain-containing protein 5 as a novel target of beta-catenin/TCF7L2 complex.
Author: Zhu, Chi|Yamaguchi, Kiyoshi|Ohsugi, Tomoyuki|Terakado, Yumi|Noguchi, Rei|Ikenoue, Tsuneo|Furukawa, Yoichi
PMID: 28117551
Journal: Mol Cancer. 2017 Jan 31;16(1):20.
Title: Up-regulated NRIP2 in colorectal cancer initiating cells modulates the Wnt pathway by targeting RORbeta.
Author: Wen, Zhenzhen|Pan, Tianhui|Yang, Saisai|Liu, Jingwen|Tao, Haiying|Zhao, Yiming|Xu, Dingting|Shao, Wei|Wu, Jia|Liu, Xiyong|Wang, Yongjiang|Mao, Jianshan|Zhu, Yongliang
PMID: 28137278
Journal: Trials. 2017 Feb 1;18(1):50.
Title: ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial.
Author: Drew, David A|Chin, Samantha M|Gilpin, Katherine K|Parziale, Melanie|Pond, Emily|Schuck, Madeline M|Stewart, Kathleen|Flagg, Meaghan|Rawlings, Crystal A|Backman, Vadim|Carolan, Peter J|Chung, Daniel C|Colizzo, Francis P 3rd|Freedman, Matthew|Gala, Manish|
PMID: 28143522
Journal: Oncol Rep. 2017 Apr;37(4):2398-2404.
Title: USP39 promotes colorectal cancer growth and metastasis through the Wnt/beta-catenin pathway.
Author: Yuan, Xianwen|Sun, Xitai|Shi, Xiaolei|Wang, Hao|Wu, Guoyi|Jiang, Chunping|Yu, Decai|Zhang, Weiwei|Xue, Bin|Ding, Yitao
PMID: 28259917
Journal: Chromosoma. 2017 Oct;126(5):655-667.
Title: Transcription-dependent radial distribution of TCF7L2 regulated genes in chromosome territories.
Author: Torabi, Keyvan|Wangsa, Darawalee|Ponsa, Immaculada|Brown, Markus|Bosch, Anna|Vila-Casadesus, Maria|Karpova, Tatiana S|Calvo, Maria|Castells, Antoni|Miro, Rosa|Ried, Thomas|Camps, Jordi
PMID: 28343235
Journal: Acta Sci Pol Technol Aliment. 2017 Jan-Mar;16(1):83-91.
Title: The genetic basis of obesity complications.
Author: Skrypnik, Katarzyna|Suliburska, Joanna|Skrypnik, Damian|Pilarski, Lukasz|Regula, Julita|Bogdanski, Pawel
PMID: 28362475
Journal: Biochem Biophys Res Commun. 2017 Jun 3;487(3):716-722.
Title: TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells.
Author: Eshelman, Melanie A|Shah, Meera|Raup-Konsavage, Wesley M|Rennoll, Sherri A|Yochum, Gregory S
PMID: 28450117
Journal: Cell Physiol Biochem. 2017;41(6):2489-2502.
Title: The Long Non-Coding RNA CRNDE Promotes Colorectal Carcinoma Progression by Competitively Binding miR-217 with TCF7L2 and Enhancing the Wnt/beta-Catenin Signaling Pathway.
Author: Yu, Bo|Ye, Xuan|Du, Qiong|Zhu, Bin|Zhai, Qing|Li, Xin-Xiang
PMID: 28472810
Journal: Mol Cancer Res. 2017 Nov;15(11):1481-1490.
Title: Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/beta-catenin Signaling.
Author: Emons, Georg|Spitzner, Melanie|Reineke, Sebastian|Moller, Janneke|Auslander, Noam|Kramer, Frank|Hu, Yue|Beissbarth, Tim|Wolff, Hendrik A|Rave-Frank, Margret|Hessmann, Elisabeth|Gaedcke, Jochen|Ghadimi, B Michael|Johnsen, Steven A|Ried, Thomas|Grade, Maria
PMID: 28811361
Journal: BMC Complement Altern Med. 2017 Sep 5;17(1):445.
Title: Anticancer activity of calyx of Diospyros kaki Thunb. through downregulation of cyclin D1 via inducing proteasomal degradation and transcriptional inhibition in human colorectal cancer cells.
Author: Park, Su Bin|Park, Gwang Hun|Song, Hun Min|Son, Ho-Jun|Um, Yurry|Kim, Hyun-Seok|Jeong, Jin Boo
PMID: 28870200
Journal: EBioMedicine. 2017 Nov;25:22-31.
Title: A Small Molecule Inhibitor of the beta-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo.
Author: Shin, Seung Ho|Lim, Do Young|Reddy, Kanamata|Malakhova, Margarita|Liu, Fangfang|Wang, Ting|Song, Mengqiu|Chen, Hanyong|Bae, Ki Beom|Ryu, Joohyun|Liu, Kangdong|Lee, Mee-Hyun|Bode, Ann M|Dong, Zigang
PMID: 29033371
Journal: Oncotarget. 2017 Aug 5;8(41):70854-70864.
Title: Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway.
Author: Li, Fei-Feng|Zhao, Zhi-Xun|Yan, Peng|Wang, Song|Liu, Zheng|Zhang, Qiong|Zhang, Xiao-Ning|Sun, Chang-Hao|Wang, Xi-Shan|Wang, Gui-Yu|Liu, Shu-Lin
PMID: 29050326
Journal: Sci Rep. 2017 Nov 8;7(1):15044.
Title: Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Significance.
Author: Coggins, Nicole B|Stultz, Jacob|O'Geen, Henriette|Carvajal-Carmona, Luis G|Segal, David J
PMID: 29118424
Journal: J BUON. 2017 Sep-Oct;22(5):1107-1114.
Title: Gene expression profiling demonstrates WNT/beta-catenin pathway genes alteration in Mexican patients with colorectal cancer and diabetes mellitus.
Author: Ivonne Wence-Chavez, Laura|Palomares-Chacon, Ulises|Pablo Flores-Gutierrez, Juan|Felipe Jave-Suarez, Luis|Del Carmen Aguilar-Lemarroy, Adriana|Barros-Nunez, Patricio|Esperanza Flores-Martinez, Silvia|Sanchez-Corona, Jose|Alejandra Rosales-Reynoso, Monica
PMID: 29135090
Journal: Front Pharmacol. 2017 Nov 24;8:877.
Title: Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/beta-Catenin Pathways via miR-130a.
Author: Dou, Huiqiang|Shen, Renhui|Tao, Jianxin|Huang, Longchang|Shi, Haoze|Chen, Hang|Wang, Yixin|Wang, Tong
PMID: 29225578
Journal: Oncotarget. 2017 Oct 26;8(59):100176-100186.
Title: Decreased expression of interferon-induced protein 2 (IFIT2) by Wnt/beta-catenin signaling confers anti-apoptotic properties to colorectal cancer cells.
Author: Ohsugi, Tomoyuki|Yamaguchi, Kiyoshi|Zhu, Chi|Ikenoue, Tsuneo|Furukawa, Yoichi
PMID: 29245969
Journal: Oncotarget. 2017 Nov 1;8(60):102176-102190.
Title: Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis.
Author: Wang, Xingmin|Yang, Yonghong|Huycke, Mark M
PMID: 29254234
Journal: Int J Cancer. 2018 Feb 1;142(3):498-513.
Title: Cumulative evidence for relationships between multiple variants in the VTI1A and TCF7L2 genes and cancer incidence.
Author: Zhang, Min|Tang, Mingshuang|Fang, Yanfei|Cui, Huijie|Chen, Siyu|Li, Junlong|Xiong, Hongyan|Lu, Jiachun|Gu, Dongqing|Zhang, Ben
PMID: 28949031
Journal: J Proteome Res. 2018 Jan 5;17(1):252-264.
Title: Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer.
Author: Torres, Sofia|Garcia-Palmero, Irene|Marin-Vicente, Consuelo|Bartolome, Ruben A|Calvino, Eva|Fernandez-Acenero, Maria Jesus|Casal, J Ignacio
PMID: 29131639
Journal: Am J Chin Med. 2018;46(1):191-207.
Title: Vitex rotundifolia Fruit Suppresses the Proliferation of Human Colorectal Cancer Cells through Down-regulation of Cyclin D1 and CDK4 via Proteasomal-Dependent Degradation and Transcriptional Inhibition.
Author: Song, Hun Min|Park, Gwang Hun|Park, Su Bin|Kim, Hyun-Seok|Son, Ho-Jun|Um, Yurry|Jeong, Jin Boo
PMID: 29298515
Journal: Genome Med. 2018 Jan 4;10(1):2.
Title: Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.
Author: Kundu, Snehangshu|Ali, Muhammad Akhtar|Handin, Niklas|Padhan, Narendra|Larsson, Jimmy|Karoutsou, Maria|Ban, Kenneth|Wisniewski, Jacek R|Artursson, Per|He, Liqun|Hellstrom, Mats|Sjoblom, Tobias
PMID: 29301589
Journal: Sci Rep. 2018 Jan 12;8(1):671.
Title: Beta-catenin cleavage enhances transcriptional activation.
Author: Goretsky, Tatiana|Bradford, Emily M|Ye, Qing|Lamping, Olivia F|Vanagunas, Tomas|Moyer, Mary Pat|Keller, Patrick C|Sinh, Preetika|Llovet, Josep M|Gao, Tianyan|She, Qing-Bai|Li, Linheng|Barrett, Terrence A
PMID: 29330435
Journal: Cancer Res. 2018 Apr 15;78(8):1958-1971.
Title: RNF6 Promotes Colorectal Cancer by Activating the Wnt/beta-Catenin Pathway via Ubiquitination of TLE3.
Author: Liu, Lei|Zhang, Yanquan|Wong, Chi Chun|Zhang, Jingwan|Dong, Yujuan|Li, Xiangchun|Kang, Wei|Chan, Francis K L|Sung, Joseph J Y|Yu, Jun
PMID: 29374067
Journal: J Biomol Struct Dyn. 2018 Mar 12:1-15.
Title: Molecular dynamics of interaction of Sesamin and related compounds with the cancer marker beta-catenin: an in silico study.
Author: Cavuturu, Bindu Madhuri|Bhandare, Vishwambar Vishnu|Ramaswamy, Amutha|Arumugam, Neelakantan
PMID: 29455637
Journal: PLoS One. 2018 Feb 20;13(2):e0192958.
Title: Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence.
Author: Marcuello, Maria|Mayol, Xavier|Felipe-Fumero, Eloisa|Costa, Jaume|Lopez-Hierro, Laia|Salvans, Silvia|Alonso, Sandra|Pascual, Marta|Grande, Luis|Pera, Miguel
PMID: 29462209
Journal: United European Gastroenterol J. 2018 Mar;6(2):290-299.
Title: Genetic Biopsy for Prediction of Surveillance Intervals after Endoscopic Resection of Colonic Polyps: Results of the GENESIS Study.
Author: Berger, Andreas W|Raedler, Katja|Langner, Cord|Ludwig, Leopold|Dikopoulos, Nektarios|Becker, Karl F|Slotta-Huspenina, Julia|Quante, Michael|Schwerdel, Daniel|Perkhofer, Lukas|Kleger, Alexander|Zizer, Eugen|Oswald, Franz|Seufferlein, Thomas|Meining, Alexan
PMID: 29511559
Journal: Oncogene. 2018 Jun;37(24):3301-3316.
Title: beta-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy.
Author: Saponaro, Concetta|Sergio, Sara|Coluccia, Antonio|De Luca, Maria|La Regina, Giuseppe|Mologni, Luca|Famiglini, Valeria|Naccarato, Valentina|Bonetti, Daniela|Gautier, Candice|Gianni, Stefano|Vergara, Daniele|Salzet, Michel|Fournier, Isabelle|Bucci, Cecilia|
PMID: 29551770
Journal: BMC Complement Altern Med. 2018 Jan 25;18(1):28.
Title: Cytotoxic activity of the twigs of Cinnamomum cassia through the suppression of cell proliferation and the induction of apoptosis in human colorectal cancer cells.
Author: Park, Gwang Hun|Song, Hun Min|Park, Su Bin|Son, Ho-Jun|Um, Yurry|Kim, Hyun-Seok|Jeong, Jin Boo
PMID: 29554905
Journal: Mol Carcinog. 2018 Oct;57(10):1278-1288.
Title: Polymorphisms in genes related to inflammation and obesity and colorectal adenoma risk.
Author: Huang, Brian Z|Tsilidis, Konstantinos K|Smith, Michael W|Hoffman-Bolton, Judith|Visvanathan, Kala|Platz, Elizabeth A|Joshu, Corinne E
PMID: 29802748
Journal: PLoS One. 2018 Jul 5;13(7):e0200215.
Title: The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2.
Author: Davidsen, Johanne|Larsen, Sylvester|Coskun, Mehmet|Gogenur, Ismail|Dahlgaard, Katja|Bennett, Eric Paul|Troelsen, Jesper Thorvald
PMID: 29975781
Journal: Stem Cell Reports. 2018 Aug 14;11(2):410-424.
Title: The Zinc Finger Transcription Factor PLAGL2 Enhances Stem Cell Fate and Activates Expression of ASCL2 in Intestinal Epithelial Cells.
Author: Strubberg, Ashlee M|Veronese Paniagua, Daniel A|Zhao, Tingting|Dublin, Leeran|Pritchard, Thomas|Bayguinov, Peter O|Fitzpatrick, James A J|Madison, Blair B
PMID: 30017821
Journal: Cancer Res. 2018 Sep 1;78(17):5164-5172.
Title: A Rare Missense Variant in TCF7L2 Associates with Colorectal Cancer Risk by Interacting with a GWAS-Identified Regulatory Variant in the MYC Enhancer.
Author: Chang, Jiang|Tian, Jianbo|Yang, Yang|Zhong, Rong|Li, Jiaoyuan|Zhai, Kan|Ke, Juntao|Lou, Jiao|Chen, Wei|Zhu, Beibei|Shen, Na|Zhang, Yi|Gong, Yajie|Zhu, Ying|Zou, Danyi|Peng, Xiating|Huang, Kun|Miao, Xiaoping
PMID: 30026326
Journal: Oncogenesis. 2018 Jul 22;7(7):55.
Title: Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer.
Author: De Nicola, Francesca|Goeman, Frauke|Pallocca, Matteo|Sperati, Francesca|Pizzuti, Laura|Melucci, Elisa|Casini, Beatrice|Amoreo, Carla Azzurra|Gallo, Enzo|Diodoro, Maria Grazia|Buglioni, Simonetta|Mazzotta, Marco|Vici, Patrizia|Sergi, Domenico|Di Lauro, Lui
PMID: 30032163
Journal: Int J Mol Sci. 2018 Aug 16;19(8). pii: ijms19082427.
Title: Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1.
Author: Hsu, Ya-Ling|Chen, Yi-Jen|Chang, Wei-An|Jian, Shu-Fang|Fan, Hsiao-Li|Wang, Jaw-Yuan|Kuo, Po-Lin
PMID: 30115896
Journal: Oncotarget. 2018 Jul 27;9(58):31214-31230.
Title: Chromatin-associated APC regulates gene expression in collaboration with canonical WNT signaling and AP-1.
Author: Hankey, William|Chen, Zhong|Bergman, Maxwell J|Fernandez, Max O|Hancioglu, Baris|Lan, Xun|Jegga, Anil G|Zhang, Jie|Jin, Victor X|Aronow, Bruce J|Wang, Qianben|Groden, Joanna
PMID: 30131849
Journal: J Exp Clin Cancer Res. 2018 Sep 25;37(1):238.
Title: MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/beta-catenin positive feedback loop.
Author: Li, Tingting|Jian, Xiangyu|He, Han|Lai, Qiuhua|Li, Xianzheng|Deng, Danling|Liu, Tengfei|Zhu, Jiehong|Jiao, Hongli|Ye, Yaping|Wang, Shuyang|Yang, Minhui|Zheng, Lin|Zhou, Weijie|Ding, Yanqing
PMID: 30253791
Journal: Genes Chromosomes Cancer. 2018 Oct 22.
Title: Colorectal cancer susceptibility loci and influence on survival.
Author: Song, Nan|Kim, Kyeezu|Shin, Aesun|Park, Ji Won|Chang, Hee Jin|Shi, Jiajun|Cai, Qiuyin|Kim, Dae Yong|Zheng, Wei|Oh, Jae Hwan
PMID: 30350386
Journal: Carcinogenesis. 2018 Oct 31. pii: 5149556.
Title: Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells.
Author: Neumeyer, Victoria|Grandl, Martina|Dietl, Alisa|Brutau-Abia, Anna|Allgauer, Michael|Kalali, Behnam|Zhang, Yang|Pan, Kai-Feng|Steiger, Katja|Vieth, Michael|Anton, Martina|Mejias-Luque, Raquel|Gerhard, Markus
PMID: 30380024