Primary Site >> Colorectal Cancer

Gene >> TCF4

Journal: Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):303-6.
Title: [beta-catenin overexpression in metastasized colorectal carcinoma--an important mechanism in progression of the disease?].
Author: Mann, B|Gratchev, A|Riede, E|Schmidt-Wolf, I|Trojanek, B|Moyer, P|Hanski, C|Buhr, H J
PMID: 14518265
Journal: Biochem Biophys Res Commun. 1999 Mar 24;256(3):584-90.
Title: Identification of Tcf4 residues involved in high-affinity beta-catenin binding.
Author: Omer, C A|Miller, P J|Diehl, R E|Kral, A M
PMID: 10080941
Journal: Genes Chromosomes Cancer. 2000 Sep;29(1):33-9.
Title: Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation.
Author: Planck, M|Wenngren, E|Borg, A|Olsson, H|Nilbert, M
PMID: 10918391
Journal: Cancer Res. 2000 Sep 1;60(17):4761-6.
Title: Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis.
Author: Yamada, T|Takaoka, A S|Naishiro, Y|Hayashi, R|Maruyama, K|Maesawa, C|Ochiai, A|Hirohashi, S
PMID: 10987283
Journal: Verh Dtsch Ges Pathol. 2000;84:175-81.
Title: [beta-Catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma].
Author: Brabletz, T|Jung, A|Dag, S|Reu, S|Kirchner, T
PMID: 11217438
Journal: Cancer Res. 2001 Feb 1;61(3):854-8.
Title: A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics.
Author: Wakita, K|Tetsu, O|McCormick, F
PMID: 11221869
Journal: J Virol. 2001 Mar;75(6):2857-65.
Title: Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway.
Author: Brunori, M|Malerba, M|Kashiwazaki, H|Iggo, R
PMID: 11222711
Journal: Cancer Res. 2001 Mar 15;61(6):2751-8.
Title: Restoration of epithelial cell polarity in a colorectal cancer cell line by suppression of beta-catenin/T-cell factor 4-mediated gene transactivation.
Author: Naishiro, Y|Yamada, T|Takaoka, A S|Hayashi, R|Hasegawa, F|Imai, K|Hirohashi, S
PMID: 11289158
Journal: Nat Genet. 2001 May;28(1):53-7.
Title: Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer.
Author: Hovanes, K|Li, T W|Munguia, J E|Truong, T|Milovanovic, T|Lawrence Marsh, J|Holcombe, R F|Waterman, M L
PMID: 11326276
Journal: J Cell Biol. 2001 Jul 23;154(2):369-87.
Title: Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.
Author: Palmer, H G|Gonzalez-Sancho, J M|Espada, J|Berciano, M T|Puig, I|Baulida, J|Quintanilla, M|Cano, A|de Herreros, A G|Lafarga, M|Munoz, A
PMID: 11470825
Journal: J Biol Chem. 2001 Nov 30;276(48):45113-9. Epub 2001 Sep 25.
Title: Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma.
Author: Rockman, S P|Currie, S A|Ciavarella, M|Vincan, E|Dow, C|Thomas, R J|Phillips, W A
PMID: 11572874
Journal: Nat Struct Biol. 2001 Dec;8(12):1048-52.
Title: Tcf4 can specifically recognize beta-catenin using alternative conformations.
Author: Graham, T A|Ferkey, D M|Mao, F|Kimelman, D|Xu, W
PMID: 11713475
Journal: Int J Cancer. 2002 Jan 1;97(1):42-51.
Title: Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate.
Author: Bordonaro, Michael|Lazarova, Darina L|Augenlicht, Leonard H|Sartorelli, Alan C
PMID: 11774242
Journal: Am J Pathol. 2002 Apr;160(4):1229-38.
Title: Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas.
Author: Zhai, Yali|Wu, Rong|Schwartz, Donald R|Darrah, Danielle|Reed, Heather|Kolligs, Frank T|Nieman, Marvin T|Fearon, Eric R|Cho, Kathleen R
PMID: 11943708
Journal: Cell Mol Biol Lett. 2002;7(1):92-5.
Title: Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.
Author: Potocnik, Uros|Ravnik-Glavac, Metka|Glavac, Damjan
PMID: 11980438
Journal: Cancer Genet Cytogenet. 2002 Apr 1;134(1):46-54.
Title: Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer.
Author: Planck, Maria|Halvarsson, Britta|Palsson, Eva|Hallen, Magnus|Ekelund, Mats|Palsson, Birger|Baldetorp, Bo|Nilbert, Mef
PMID: 11996796
Journal: FEBS Lett. 2002 May 8;518(1-3):83-7.
Title: Stimulation of Cdx1 by oncogenic beta-catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein.
Author: Domon-Dell, Claire|Freund, Jean-Noel
PMID: 11997022
Journal: Cancer Res. 2002 Oct 15;62(20):5651-6.
Title: Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Author: Takahashi, Meiko|Fujita, Manabu|Furukawa, Yoichi|Hamamoto, Ryuji|Shimokawa, Takashi|Miwa, Nobutomo|Ogawa, Michio|Nakamura, Yusuke
PMID: 12384519
Journal: J Nutr. 2002 Dec;132(12):3804S-3808S.
Title: Short chain fatty acids and colon cancer.
Author: Augenlicht, Leonard H|Mariadason, John M|Wilson, Andrew|Arango, Diego|Yang, WanCai|Heerdt, Barbara G|Velcich, Anna
PMID: 12468628
Journal: Digestion. 2002;66(3):131-44.
Title: Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.
Author: Kolligs, Frank T|Bommer, Guido|Goke, Burkhard
PMID: 12481159
Journal: Mol Cancer Ther. 2003 Jan;2(1):113-21.
Title: Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy.
Author: Kirmizis, Antonis|Bartley, Stephanie M|Farnham, Peggy J
PMID: 12533679
Journal: Mamm Genome. 2003 Feb;14(2):119-29.
Title: Exclusion of Madh2, Madh4, and Madh7 as candidates for the modifier of Min 2 (Mom2) locus.
Author: Silverman, Karen A|Koratkar, Revati A|Siracusa, Linda D|Buchberg, Arthur M
PMID: 12584607
Journal: J Biol Chem. 2003 May 30;278(22):20259-67. Epub 2003 Mar 21.
Title: The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway.
Author: Ghiselli, Giancarlo|Coffee, Nefeteria|Munnery, Christine E|Koratkar, Revati|Siracusa, Linda D
PMID: 12651860
Journal: EMBO Rep. 2003 Jun;4(6):609-15.
Title: Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector.
Author: van de Wetering, Marc|Oving, Irma|Muncan, Vanesa|Pon Fong, Menno Tjon|Brantjes, Helen|van Leenen, Dik|Holstege, Frank C P|Brummelkamp, Thijn R|Agami, Reuven|Clevers, Hans
PMID: 12776180
Journal: Dev Biol. 2003 Jul 15;259(2):258-71.
Title: Wnt signaling during development of the gastrointestinal tract.
Author: Theodosiou, Nicole A|Tabin, Clifford J
PMID: 12871700
Journal: Int J Cancer. 2003 Nov 1;107(2):229-37.
Title: Overexpression of the beta-catenin binding domain of cadherin selectively kills colorectal cancer cells.
Author: Pierce, Michael|Wang, Chunwei|Stump, Mark|Kamb, Alexander
PMID: 12949799
Journal: Cancer Res. 2003 Oct 1;63(19):6116-20.
Title: Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Author: Shimokawa, Takashi|Furukawa, Yoichi|Sakai, Michihiro|Li, Meihua|Miwa, Nobutomo|Lin, Yu-Min|Nakamura, Yusuke
PMID: 14559787
Journal: Cancer Res. 2003 Dec 15;63(24):8726-34.
Title: TIP49 regulates beta-catenin-mediated neoplastic transformation and T-cell factor target gene induction via effects on chromatin remodeling.
Author: Feng, Ying|Lee, Nana|Fearon, Eric R
PMID: 14695187
Journal: Cancer Cell. 2004 Jan;5(1):5-6.
Title: Wnt breakers in colon cancer.
Author: Clevers, Hans
PMID: 14749120
Journal: Nat Genet. 2004 Mar;36(3):277-82. Epub 2004 Feb 8.
Title: Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation.
Author: van den Brink, Gijs R|Bleuming, Sylvia A|Hardwick, James C H|Schepman, Berber L|Offerhaus, G Johan|Keller, Josbert J|Nielsen, Corinne|Gaffield, William|van Deventer, Sander J H|Roberts, Drucilla J|Peppelenbosch, Maikel P
PMID: 14770182
Journal: J Nutr. 2004 May;134(5):1157-61.
Title: Dietary soy sphingolipids suppress tumorigenesis and gene expression in 1,2-dimethylhydrazine-treated CF1 mice and ApcMin/+ mice.
Author: Symolon, Holly|Schmelz, Eva M|Dillehay, Dirck L|Merrill, Alfred H Jr
PMID: 15113963
Journal: Int J Cancer. 2004 Jul 1;110(4):523-31.
Title: Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate.
Author: Lazarova, Darina L|Bordonaro, Michael|Carbone, Rocco|Sartorelli, Alan C
PMID: 15122584
Journal: Nucleic Acids Res. 2004 May 11;32(8):2660-74.
Title: Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells.
Author: Bordonaro, Michael|Lazarova, Darina L|Sartorelli, Alan C
PMID: 15141037
Journal: Ai Zheng. 2004 Jul;23(7):737-41.
Title: [Indomethacin induces apoptosis through inhibition of survivin regulated by beta-catenin/TCF4 in human colorectal cancer cells].
Author: Zhu, Hong-Xia|Zhang, Guo|Wang, Yi-Hua|Zhou, Cui-Qi|Bai, Jin-Feng|Xu, Ning-Zhi
PMID: 15248904
Journal: Oncogene. 2005 Jan 20;24(4):597-604.
Title: beta-Catenin activates the growth factor endothelin-1 in colon cancer cells.
Author: Kim, Tae Hoon|Xiong, Hui|Zhang, Zhuohua|Ren, Bing
PMID: 15558022
Journal: Oncogene. 2005 Feb 3;24(6):1098-103.
Title: The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer.
Author: Gonzalez-Sancho, Jose Manuel|Aguilera, Oscar|Garcia, Jose Miguel|Pendas-Franco, Natalia|Pena, Cristina|Cal, Santiago|Garcia de Herreros, Antonio|Bonilla, Felix|Munoz, Alberto
PMID: 15592505
Journal: Cancer Res. 2005 Jan 15;65(2):493-8.
Title: Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3).
Author: Chakrabarty, Subhas|Wang, Hongmei|Canaff, Lucie|Hendy, Geoffrey N|Appelman, Henry|Varani, James
PMID: 15695391
Journal: Development. 2005 Mar;132(6):1443-51.
Title: Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.
Author: Andreu, Pauline|Colnot, Sabine|Godard, Cecile|Gad, Sophie|Chafey, Philippe|Niwa-Kawakita, Michiko|Laurent-Puig, Pierre|Kahn, Axel|Robine, Sylvie|Perret, Christine|Romagnolo, Beatrice
PMID: 15716339
Journal: Nat Cell Biol. 2005 Apr;7(4):381-6.
Title: Wnt signalling induces maturation of Paneth cells in intestinal crypts.
Author: van Es, Johan H|Jay, Philippe|Gregorieff, Alex|van Gijn, Marielle E|Jonkheer, Suzanne|Hatzis, Pantelis|Thiele, Andrea|van den Born, Maaike|Begthel, Harry|Brabletz, Thomas|Taketo, Makoto M|Clevers, Hans
PMID: 15778706
Journal: Biochem J. 2005 Sep 1;390(Pt 2):493-9.
Title: The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway.
Author: Ghiselli, Giancarlo|Agrawal, Amit
PMID: 15853773
Journal: Biochim Biophys Acta. 2005 Jun 15;1735(1):30-40. Epub 2005 Feb 16.
Title: Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: effects on proliferation, differentiation, and gene expression.
Author: Lampen, A|Leifheit, M|Voss, J|Nau, H
PMID: 15935729
Journal: Am J Pathol. 2005 Jul;167(1):233-42.
Title: The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis.
Author: Brouland, Jean-Philippe|Gelebart, Pascal|Kovacs, Tunde|Enouf, Jocelyne|Grossmann, Johannes|Papp, Bela
PMID: 15972967
Journal: Nature. 2005 Jun 23;435(7045):1126-30.
Title: EphB receptor activity suppresses colorectal cancer progression.
Author: Batlle, Eduard|Bacani, Julinor|Begthel, Harry|Jonkheer, Suzanne|Gregorieff, Alexander|van de Born, Maaike|Malats, Nuria|Sancho, Elena|Boon, Elles|Pawson, Tony|Gallinger, Steven|Pals, Steven|Clevers, Hans
PMID: 15973414
Journal: Carcinogenesis. 2006 Mar;27(3):454-64. Epub 2005 Nov 4.
Title: Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours.
Author: Guo, Dong Li|Zhang, Ji|Yuen, Siu Tsan|Tsui, Wai Yin|Chan, Annie S Y|Ho, Coral|Ji, Jiafu|Leung, Suet Yi|Chen, Xin
PMID: 16272170
Journal: Oncogene. 2006 May 18;25(21):3065-70.
Title: Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis.
Author: Giles, R H|Lolkema, M P|Snijckers, C M|Belderbos, M|van der Groep, P|Mans, D A|van Beest, M|van Noort, M|Goldschmeding, R|van Diest, P J|Clevers, H|Voest, E E
PMID: 16407833
Journal: Dis Colon Rectum. 2006 Mar;49(3):399-406.
Title: Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer.
Author: Yamaguchi, Tatsuro|Iijima, Takeru|Mori, Takeo|Takahashi, Keiichi|Matsumoto, Hiroshi|Miyamoto, Hidenori|Hishima, Tsunekazu|Miyaki, Michiko
PMID: 16421660
Journal: J Cell Sci. 2006 Mar 1;119(Pt 5):819-27. Epub 2006 Feb 14.
Title: APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
Author: Park, Ki-Sook|Jeon, Soung Hoo|Kim, Sung-Eun|Bahk, Young-Yil|Holmen, Sheri L|Williams, Bart O|Chung, Kwang-Chul|Surh, Young-Joon|Choi, Kang-Yell
PMID: 16478791
Journal: Cancer Res. 2006 Feb 15;66(4):2279-86.
Title: SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling.
Author: Coluccia, Addolorata Maria Luce|Benati, Daniela|Dekhil, Hafedh|De Filippo, Annamaria|Lan, Cathy|Gambacorti-Passerini, Carlo
PMID: 16489032
Journal: J Biol Chem. 2006 Jun 2;281(22):15405-11. Epub 2006 Mar 28.
Title: Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells.
Author: Tzeng, Shu-Ling|Cheng, Yu-Wen|Li, Ching-Hao|Lin, Young-Sun|Hsu, Hey-Chi|Kang, Jaw-Jou
PMID: 16569639
Journal: Cancer Res. 2006 Aug 1;66(15):7571-7.
Title: Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.
Author: Shelton, Dawne N|Sandoval, Imelda T|Eisinger, Annie|Chidester, Stephanie|Ratnayake, Anokha|Ireland, Chris M|Jones, David A
PMID: 16885356
Journal: Mol Cell Biol. 2006 Nov;26(22):8418-26. Epub 2006 Sep 5.
Title: Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.
Author: Muncan, Vanesa|Sansom, Owen J|Tertoolen, Leon|Phesse, Toby J|Begthel, Harry|Sancho, Elena|Cole, Alicia M|Gregorieff, Alex|de Alboran, Ignacio Moreno|Clevers, Hans|Clarke, Alan R
PMID: 16954380
Journal: Oncogene. 2006 Dec 4;25(57):7531-7.
Title: Colorectal cancer and genetic alterations in the Wnt pathway.
Author: Segditsas, S|Tomlinson, I
PMID: 17143297
Journal: J Biol Chem. 2007 Jan 12;282(2):871-8. Epub 2006 Nov 22.
Title: An antisense transcript induced by Wnt/beta-catenin signaling decreases E2F4.
Author: Yochum, Gregory S|Cleland, Ryan|McWeeney, Shannon|Goodman, Richard H
PMID: 17121828
Journal: Gastroenterology. 2007 Feb;132(2):628-32. Epub 2006 Aug 18.
Title: The Intestinal Wnt/TCF Signature.
Author: Van der Flier, Laurens G|Sabates-Bellver, Jacob|Oving, Irma|Haegebarth, Andrea|De Palo, Mariagrazia|Anti, Marcello|Van Gijn, Marielle E|Suijkerbuijk, Saskia|Van de Wetering, Marc|Marra, Giancarlo|Clevers, Hans
PMID: 17320548
Journal: Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3324-9. Epub 2007 Feb 21.
Title: Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells.
Author: Yochum, Gregory S|McWeeney, Shannon|Rajaraman, Veena|Cleland, Ryan|Peters, Sandra|Goodman, Richard H
PMID: 17360646
Journal: EMBO J. 2007 May 2;26(9):2284-94. Epub 2007 Apr 5.
Title: CBP/p300 are bimodal regulators of Wnt signaling.
Author: Li, Jiong|Sutter, Chris|Parker, David S|Blauwkamp, Timothy|Fang, Ming|Cadigan, Ken M
PMID: 17410209
Journal: J Mol Signal. 2007 Jul 16;2:6.
Title: Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling.
Author: Schepeler, Troels|Mansilla, Francisco|Christensen, Lise L|Orntoft, Torben F|Andersen, Claus L
PMID: 17634137
Journal: Nat Genet. 2007 Nov;39(11):1376-83. Epub 2007 Sep 30.
Title: EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.
Author: Cortina, Carme|Palomo-Ponce, Sergio|Iglesias, Mar|Fernandez-Masip, Juan Luis|Vivancos, Ana|Whissell, Gavin|Huma, Mireia|Peiro, Nerea|Gallego, Lourdes|Jonkheer, Suzanne|Davy, Alice|Lloreta, Josep|Sancho, Elena|Batlle, Eduard
PMID: 17906625
Journal: Mol Cell Biol. 2008 Apr;28(8):2732-44.
Title: Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.
Author: Hatzis, Pantelis|van der Flier, Laurens G|van Driel, Marc A|Guryev, Victor|Nielsen, Fiona|Denissov, Sergei|Nijman, Isaac J|Koster, Jan|Santo, Evan E|Welboren, Willem|Versteeg, Rogier|Cuppen, Edwin|van de Wetering, Marc|Clevers, Hans|Stunnenberg, Hendrik G
PMID: 18268006
Journal: Biol Pharm Bull. 2008 May;31(5):916-20.
Title: Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism.
Author: Yamakawa, Satoshi|Demizu, Aya|Kawaratani, Yasuyuki|Nagaoka, Yasuo|Terada, Yuji|Maruyama, Sakiko|Uesato, Shinichi
PMID: 18451518
Journal: Pediatr Blood Cancer. 2008 Sep;51(3):349-55.
Title: Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival.
Author: Chen, Kevin|Fallen, Shannon|Abaan, Hatice Ozel|Hayran, Mutlu|Gonzalez, Corina|Wodajo, Felasfa|MacDonald, Tobey|Toretsky, Jeffrey A|Uren, Aykut
PMID: 18465804
Journal: Biochim Biophys Acta. 2008 Dec;1782(12):800-8.
Title: The ubiquitin-proteasome system in colorectal cancer.
Author: Voutsadakis, Ioannis A
PMID: 18619533
Journal: Cancer Cell. 2008 Sep 9;14(3):226-37.
Title: RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.
Author: Ito, Kosei|Lim, Anthony Chee-Beng|Salto-Tellez, Manuel|Motoda, Lena|Osato, Motomi|Chuang, Linda Shyue Huey|Lee, Cecilia Wei Lin|Voon, Dominic Chih-Cheng|Koo, Jason Kin Wai|Wang, Huajing|Fukamachi, Hiroshi|Ito, Yoshiaki
PMID: 18772112
Journal: Mol Cell Biol. 2008 Dec;28(24):7368-79.
Title: A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression.
Author: Yochum, Gregory S|Cleland, Ryan|Goodman, Richard H
PMID: 18852287
Journal: Exp Cell Res. 2008 Dec 10;314(20):3712-23.
Title: KLF4 regulation in intestinal epithelial cell maturation.
Author: Flandez, M|Guilmeau, S|Blache, P|Augenlicht, L H
PMID: 18977346
Journal: BMC Cancer. 2008 Nov 8;8:328.
Title: Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors.
Author: Takeda, Kayoko|Kinoshita, Ichiro|Shimizu, Yasushi|Ohba, Yusuke|Itoh, Tomoo|Matsuno, Yoshihiro|Shichinohe, Toshiaki|Dosaka-Akita, Hirotoshi
PMID: 18992165
Journal: J Pharmacol Sci. 2008 Dec;108(4):535-44. Epub 2008 Dec 10.
Title: Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine.
Author: Fujisawa, Toshio|Sugiyama, Michiko|Tomimoto, Ayako|Wada, Koichiro|Endo, Hiroki|Takahashi, Hirokazu|Yoneda, Kyoko|Yoneda, Masato|Inamori, Masahiko|Saito, Satoru|Terauchi, Yasuo|Kadowaki, Takashi|Tsuchiya, Naoto|Nakagama, Hitoshi|Nakajima, Atsushi
PMID: 19075513
Journal: Gastroenterology. 2009 Jan;136(1):196-205.e2.
Title: p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors.
Author: Wassermann, Stella|Scheel, Silvio K|Hiendlmeyer, Elke|Palmqvist, Richard|Horst, David|Hlubek, Falk|Haynl, Angela|Kriegl, Lydia|Reu, Simone|Merkel, Susanne|Brabletz, Thomas|Kirchner, Thomas|Jung, Andreas
PMID: 18951899
Journal: Gene. 2009 Mar 1;432(1-2):112-7.
Title: The Bcl-w promoter is activated by beta-catenin/TCF4 in human colorectal carcinoma cells.
Author: Lapham, Abigail|Adams, Jemimah E|Paterson, Alex|Lee, Melanie|Brimmell, Matthew|Packham, Graham
PMID: 19124064
Journal: Cancer Res. 2009 Feb 15;69(4):1343-9.
Title: Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity.
Author: Song, Shumei|Mazurek, Nachman|Liu, Chunming|Sun, Yunjie|Ding, Qing Qing|Liu, Kaifeng|Hung, Mien-Chie|Bresalier, Robert S
PMID: 19190323
Journal: Gastroenterology. 2009 Aug;137(2):639-48, 648.e1-9.
Title: ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition.
Author: Herbst, Andreas|Bommer, Guido T|Kriegl, Lydia|Jung, Andreas|Behrens, Andrea|Csanadi, Endy|Gerhard, Markus|Bolz, Christian|Riesenberg, Rainer|Zimmermann, Wolfgang|Dietmaier, Wolfgang|Wolf, Isabella|Brabletz, Thomas|Goke, Burkhard|Kolligs, Frank T
PMID: 19394332
Journal: Int J Colorectal Dis. 2009 Aug;24(8):875-84.
Title: Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer.
Author: Fang, Y J|Lu, Z H|Wang, G Q|Pan, Z Z|Zhou, Z W|Yun, J P|Zhang, M F|Wan, D S
PMID: 19421758
Journal: Nat Genet. 2009 Aug;41(8):885-90.
Title: The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.
Author: Tuupanen, Sari|Turunen, Mikko|Lehtonen, Rainer|Hallikas, Outi|Vanharanta, Sakari|Kivioja, Teemu|Bjorklund, Mikael|Wei, Gonghong|Yan, Jian|Niittymaki, Iina|Mecklin, Jukka-Pekka|Jarvinen, Heikki|Ristimaki, Ari|Di-Bernardo, Mariachiara|East, Phil|Carvajal-Ca
PMID: 19561604
Journal: Hum Mol Genet. 2009 Oct 1;18(19):3696-707.
Title: Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.
Author: Goncalves, Vania|Matos, Paulo|Jordan, Peter
PMID: 19602482
Journal: J Pathol. 2009 Sep;219(1):103-13.
Title: c-Rel is a transcriptional repressor of EPHB2 in colorectal cancer.
Author: Fu, Tao|Li, Peng|Wang, Hanzhi|He, Yujun|Luo, Donglin|Zhang, Anping|Tong, Weidong|Zhang, Lianyang|Liu, Baohua|Hu, Chuanmin
PMID: 19621336
Journal: Biochem Biophys Res Commun. 2009 Oct 2;387(4):736-40.
Title: The transcription factor ITF-2A induces cell cycle arrest via p21(Cip1).
Author: Herbst, Andreas|Helferich, Simone|Behrens, Andrea|Goke, Burkhard|Kolligs, Frank T
PMID: 19635457
Journal: Cancer Microenviron. 2009 Sep 25;2(1):69-80.
Title: The NF-kappaB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1beta.
Author: Kaler, Pawan|Godasi, Bramara N|Augenlicht, Leonard|Klampfer, Lidija
PMID: 19779850
Journal: EMBO J. 2009 Nov 4;28(21):3329-40.
Title: The kinase TNIK is an essential activator of Wnt target genes.
Author: Mahmoudi, Tokameh|Li, Vivian S W|Ng, Ser Sue|Taouatas, Nadia|Vries, Robert G J|Mohammed, Shabaz|Heck, Albert J|Clevers, Hans
PMID: 19816403
Journal: Oncogene. 2010 Jan 7;29(1):128-38.
Title: Downregulation of E-cadherin is an essential event in activating beta-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells.
Author: Wang, Q|Sun, Z-X|Allgayer, H|Yang, H-S
PMID: 19784072
Journal: Mol Cell Biol. 2010 Jan;30(2):372-81.
Title: KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin.
Author: Evans, Paul M|Chen, Xi|Zhang, Wen|Liu, Chunming
PMID: 19901072
Journal: Chem Commun (Camb). 2010 Jun 21;46(23):4021-42.
Title: Total synthesis of (+)-A83586C, (+)-kettapeptin and (+)-azinothricin: powerful new inhibitors of beta-catenin/TCF4- and E2F-mediated gene transcription.
Author: Hale, Karl J|Manaviazar, Soraya|George, Jonathan
PMID: 20405066
Journal: Int J Oncol. 2010 Jun;36(6):1573-80.
Title: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells.
Author: Wang, Xize|Chen, Wei|Singh, Navneet|Promkan, Multira|Liu, Guangming
PMID: 20428782
Journal: Mol Cancer. 2010 May 11;9:104.
Title: The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors.
Author: Sturgill, Thomas W|Stoddard, Paul B|Cohn, Steven M|Mayo, Marty W
PMID: 20459822
Journal: Nucleic Acids Res. 2010 Sep;38(17):5735-45.
Title: Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq.
Author: Bottomly, Daniel|Kyler, Sydney L|McWeeney, Shannon K|Yochum, Gregory S
PMID: 20460455
Journal: Cancer Res. 2010 Jun 15;70(12):5024-33.
Title: Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth.
Author: Shitashige, Miki|Satow, Reiko|Jigami, Takafumi|Aoki, Kazunori|Honda, Kazufumi|Shibata, Tatsuhiro|Ono, Masaya|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 20530691
Journal: Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15157-62.
Title: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Author: Verzi, Michael P|Hatzis, Pantelis|Sulahian, Rita|Philips, Juliet|Schuijers, Jurian|Shin, Hyunjin|Freed, Ellen|Lynch, John P|Dang, Duyen T|Brown, Myles|Clevers, Hans|Liu, X Shirley|Shivdasani, Ramesh A
PMID: 20696899
Journal: Acta Biochim Biophys Sin (Shanghai). 2010 Jul;42(7):450-6.
Title: NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer.
Author: Guo, Qin|Shen, Shourong|Liao, Mantian|Lian, Ping|Wang, Xiaoyan
PMID: 20705583
Journal: Cancer Res. 2010 Sep 15;70(18):7253-63.
Title: Colorectal tumors are effectively eradicated by combined inhibition of {beta}-catenin, KRAS, and the oncogenic transcription factor ITF2.
Author: Mologni, Luca|Dekhil, Hafedh|Ceccon, Monica|Purgante, Stefania|Lan, Cathy|Cleris, Loredana|Magistroni, Vera|Formelli, Franca|Gambacorti-Passerini, Carlo B
PMID: 20823162
Journal: J Transl Med. 2010 Nov 22;8:123.
Title: LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer.
Author: Kriegl, Lydia|Horst, David|Reiche, Jana A|Engel, Jutta|Kirchner, Thomas|Jung, Andreas
PMID: 21092222
Journal: PLoS Biol. 2010 Nov 16;8(11):e1000539.
Title: The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis.
Author: Mahmoudi, Tokameh|Boj, Sylvia F|Hatzis, Pantelis|Li, Vivian S W|Taouatas, Nadia|Vries, Robert G J|Teunissen, Hans|Begthel, Harry|Korving, Jeroen|Mohammed, Shabaz|Heck, Albert J R|Clevers, Hans
PMID: 21103407
Journal: Mol Cell Proteomics. 2011 Jan;10(1):M110.002998.
Title: Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway.
Author: Thorsen, Kasper|Mansilla, Francisco|Schepeler, Troels|Oster, Bodil|Rasmussen, Mads H|Dyrskjot, Lars|Karni, Rotem|Akerman, Martin|Krainer, Adrian R|Laurberg, Soren|Andersen, Claus L|Orntoft, Torben F
PMID: 20938052
Journal: Cell Res. 2011 May;21(5):730-40.
Title: A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis.
Author: Wang, Wei|Liu, Haiyang|Wang, Sheng|Hao, Xiaojiang|Li, Lin
PMID: 21321609
Journal: Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4914-9.
Title: T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis.
Author: Angus-Hill, Melinda L|Elbert, Kathryn M|Hidalgo, Julio|Capecchi, Mario R
PMID: 21383188
Journal: Physiol Genomics. 2011 May 1;43(10):640-54.
Title: Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet.
Author: Shah, Manasvi S|Schwartz, Scott L|Zhao, Chen|Davidson, Laurie A|Zhou, Beiyan|Lupton, Joanne R|Ivanov, Ivan|Chapkin, Robert S
PMID: 21406606
Journal: Pathology. 2011 Apr;43(3):220-7.
Title: A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors.
Author: Ernst, Aurelie|Aigner, Maximilian|Nakata, Susumu|Engel, Felix|Schlotter, Magdalena|Kloor, Matthias|Brand, Karsten|Schmitt, Steffen|Steinert, Gunnar|Rahbari, Nuh|Koch, Moritz|Radlwimmer, Bernhard|Weitz, Jurgen|Lichter, Peter
PMID: 21436631
Journal: J Biol Chem. 2011 May 27;286(21):19170-7.
Title: Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4).
Author: Togi, Sumihito|Ikeda, Osamu|Kamitani, Shinya|Nakasuji, Misa|Sekine, Yuichi|Muromoto, Ryuta|Nanbo, Asuka|Oritani, Kenji|Kawai, Taro|Akira, Shizuo|Matsuda, Tadashi
PMID: 21454679
Journal: Exp Cell Res. 2011 Jun 10;317(10):1368-81.
Title: The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways.
Author: Bordonaro, Michael|Tewari, Shruti|Atamna, Wafa|Lazarova, Darina L
PMID: 21473864
Journal: PLoS One. 2011 Apr 20;6(4):e18966.
Title: Multiple Wnt/ss-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops.
Author: Yochum, Gregory S
PMID: 21533051
Journal: BMC Cancer. 2011 Jun 13;11:238.
Title: COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status.
Author: Asting, Annika Gustafsson|Caren, Helena|Andersson, Marianne|Lonnroth, Christina|Lagerstedt, Kristina|Lundholm, Kent
PMID: 21668942
Journal: Nat Genet. 2011 Sep 4;43(10):964-8.
Title: Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
Author: Bass, Adam J|Lawrence, Michael S|Brace, Lear E|Ramos, Alex H|Drier, Yotam|Cibulskis, Kristian|Sougnez, Carrie|Voet, Douglas|Saksena, Gordon|Sivachenko, Andrey|Jing, Rui|Parkin, Melissa|Pugh, Trevor|Verhaak, Roel G|Stransky, Nicolas|Boutin, Adam T|Barretin
PMID: 21892161
Journal: Carcinogenesis. 2011 Dec;32(12):1824-31.
Title: Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.
Author: Kendziorra, Emil|Ahlborn, Kerstin|Spitzner, Melanie|Rave-Frank, Margret|Emons, Georg|Gaedcke, Jochen|Kramer, Frank|Wolff, Hendrik A|Becker, Heinz|Beissbarth, Tim|Ebner, Reinhard|Ghadimi, B Michael|Pukrop, Tobias|Ried, Thomas|Grade, Marian
PMID: 21983179
Journal: Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19204-9.
Title: beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.
Author: Sanchez-Tillo, Ester|de Barrios, Oriol|Siles, Laura|Cuatrecasas, Miriam|Castells, Antoni|Postigo, Antonio
PMID: 22080605
Journal: Gut. 2012 May;61(5):714-24.
Title: The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling.
Author: Chen, Hang-Zi|Liu, Qing-Feng|Li, Li|Wang, Wei-Jia|Yao, Lu-Ming|Yang, Meng|Liu, Bo|Chen, Wei|Zhan, Yan-Yan|Zhang, Ming-Qing|Cai, Jian-Chun|Zheng, Zhong-hui|Lin, Sheng-Cai|Li, Bo-An|Wu, Qiao
PMID: 21873734
Journal: Int J Oncol. 2012 Feb;40(2):519-26.
Title: Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer.
Author: Lan, Fengming|Yue, Xiao|Han, Lei|Shi, Zhendong|Yang, Yang|Pu, Peiyu|Yao, Zhi|Kang, Chunsheng
PMID: 21956205
Journal: Oncogene. 2012 May 31;31(22):2750-60.
Title: Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes.
Author: Schepeler, T|Holm, A|Halvey, P|Nordentoft, I|Lamy, P|Riising, E M|Christensen, L L|Thorsen, K|Liebler, D C|Helin, K|Orntoft, T F|Andersen, C L
PMID: 21963845
Journal: Gut. 2012 Sep;61(9):1306-14.
Title: beta-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.
Author: Smartt, Helena J M|Greenhough, Alexander|Ordonez-Moran, Paloma|Talero, Elena|Cherry, Catherine A|Wallam, Catherine A|Parry, Lee|Al Kharusi, Manal|Roberts, Heather R|Mariadason, John M|Clarke, Alan R|Huelsken, Joerg|Williams, Ann C|Paraskeva, Chris
PMID: 22082586
Journal: Cancer Lett. 2012 Apr 1;317(1):65-71.
Title: P-21 activated kinase 1 knockdown inhibits beta-catenin signalling and blocks colorectal cancer growth.
Author: He, Hong|Huynh, Nhi|Liu, Kevin H|Malcontenti-Wilson, Cathy|Zhu, Jin|Christophi, Christopher|Shulkes, Arthur|Baldwin, Graham S
PMID: 22100495
Journal: Mol Endocrinol. 2012 Jan;26(1):37-51.
Title: VDR/RXR and TCF4/beta-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression.
Author: Meyer, Mark B|Goetsch, Paul D|Pike, J Wesley
PMID: 22108803
Journal: Biochemistry. 2012 Jan 17;51(2):724-31.
Title: Structure-based discovery of a novel inhibitor targeting the beta-catenin/Tcf4 interaction.
Author: Tian, Wang|Han, Xiaofeng|Yan, Maocai|Xu, Yan|Duggineni, Srinivas|Lin, Nan|Luo, Guifen|Li, Yan Michael|Han, Xiaobing|Huang, Ziwei|An, Jing
PMID: 22224445
Journal: J Med Chem. 2012 Feb 9;55(3):1346-59.
Title: Design, synthesis, and biological evaluation of new diaminoquinazolines as beta-catenin/Tcf4 pathway inhibitors.
Author: Mao, Yongjun|Lin, Nan|Tian, Wang|Han, Xiaofeng|Han, Xiaobing|Huang, Ziwei|An, Jing
PMID: 22229647
Journal: J Biol Chem. 2012 Apr 6;287(15):11730-9.
Title: Wnt/beta-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells.
Author: Konsavage, Wesley M Jr|Kyler, Sydney L|Rennoll, Sherri A|Jin, Ge|Yochum, Gregory S
PMID: 22337891
Journal: Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41.
Title: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.
Author: Yeh, Chi-Tai|Rao, Yerra Koteswara|Ye, Min|Wu, Wen-Shi|Chang, Tung-Chen|Wang, Liang-Shun|Wu, Chih-Hsiung|Wu, Alexander T H|Tzeng, Yew-Min
PMID: 22465936
Journal: PLoS One. 2012;7(5):e37013.
Title: MENA is a transcriptional target of the Wnt/beta-catenin pathway.
Author: Najafov, Ayaz|Seker, Tuncay|Even, Ipek|Hoxhaj, Gerta|Selvi, Osman|Ozel, Duygu Esen|Koman, Ahmet|Birgul-Iyison, Necla
PMID: 22615875
Journal: EMBO J. 2012 Jun 13;31(12):2685-96.
Title: Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins.
Author: Schuijers, Jurian|Clevers, Hans
PMID: 22617424
Journal: Biochem Pharmacol. 2012 Nov 1;84(9):1143-53.
Title: The beta-catenin/TCF complex as a novel target of resveratrol in the Wnt/beta-catenin signaling pathway.
Author: Chen, Hui-Jye|Hsu, Le-Shiang|Shia, Yu-Ting|Lin, Meng-Wei|Lin, Chung-Ming
PMID: 22935447
Journal: PLoS One. 2012;7(9):e45462.
Title: Activating mutations in beta-catenin in colon cancer cells alter their interaction with macrophages; the role of snail.
Author: Kaler, Pawan|Augenlicht, Leonard|Klampfer, Lidija
PMID: 23029025
Journal: PLoS One. 2012;7(12):e51205.
Title: Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.
Author: Barrett, Caitlyn W|Smith, J Joshua|Lu, Lauren C|Markham, Nicholas|Stengel, Kristy R|Short, Sarah P|Zhang, Baolin|Hunt, Aubrey A|Fingleton, Barbara M|Carnahan, Robert H|Engel, Michael E|Chen, Xi|Beauchamp, R Daniel|Wilson, Keith T|Hiebert, Scott W|Reynolds
PMID: 23251453
Journal: Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.
Title: Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Author: Ho, Koc-Kan|Parnell, K Mark|Yuan, Yi|Xu, Yong|Kultgen, Steven G|Hamblin, Steven|Hendrickson, Thomas F|Luo, Bai|Foulks, Jason M|McCullar, Michael V|Kanner, Steven B
PMID: 23232060
Journal: Clin Cancer Res. 2013 Mar 1;19(5):1071-82.
Title: ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1.
Author: Sanchez-Tillo, Ester|de Barrios, Oriol|Siles, Laura|Amendola, Pier G|Darling, Douglas S|Cuatrecasas, Miriam|Castells, Antoni|Postigo, Antonio
PMID: 23340304
Journal: J Cancer. 2013;4(2):96-103.
Title: Crosstalk between Wnt Signaling and RNA Processing in Colorectal Cancer.
Author: Bordonaro, Michael
PMID: 23386908
Journal: Dig Dis Sci. 2013 Sep;58(9):2507-17.
Title: Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis.
Author: Sadik, Nermin Abdel Hamid|Shaker, Olfat Gamil
PMID: 23722564
Journal: PLoS One. 2013 Jul 2;8(7):e68525.
Title: Henryin, an ent-kaurane diterpenoid, inhibits Wnt signaling through interference with beta-catenin/TCF4 interaction in colorectal cancer cells.
Author: Li, Xingyao|Pu, Jianxin|Jiang, Shiyou|Su, Jia|Kong, Lingmei|Mao, Bingyu|Sun, Handong|Li, Yan
PMID: 23844215
Journal: Int J Med Sci. 2013 Nov 25;10(13):1888-98.
Title: Modulation of beta-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways.
Author: Zhang, Wenwen|Zhang, Hongyu|Wang, Ning|Zhao, Chen|Zhang, Hongmei|Deng, Fang|Wu, Ningning|He, Yunfeng|Chen, Xian|Zhang, Junhui|Wen, Sheng|Liao, Zhan|Zhang, Qian|Zhang, Zhonglin|Liu, Wei|Yan, Zhengjian|Luu, Hue H|Haydon, Rex C|Zhou, Lan|He, Tong-Chuan
PMID: 24324366
Journal: Ann Surg Oncol. 2014 Dec;21 Suppl 4:S515-21.
Title: Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer.
Author: Sugimachi, Keishi|Niida, Atsushi|Yamamoto, Ken|Shimamura, Teppei|Imoto, Seiya|Iinuma, Hisae|Shinden, Yoshiaki|Eguchi, Hidetoshi|Sudo, Tomoya|Watanabe, Masahiko|Tanaka, Junichi|Kudo, Shinei|Hase, Kazuo|Kusunoki, Masato|Yamada, Kazutaka|Shimada, Yasuhiro|Su
PMID: 24390711
Journal: EMBO J. 2014 Jan 13;33(2):146-56.
Title: Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.
Author: Schuijers, Jurian|Mokry, Michal|Hatzis, Pantelis|Cuppen, Edwin|Clevers, Hans
PMID: 24413017
Journal: PLoS One. 2014 Jan 22;9(1):e86582.
Title: Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.
Author: Takahashi, Norihiko|Yamaguchi, Kiyoshi|Ikenoue, Tsuneo|Fujii, Tomoaki|Furukawa, Yoichi
PMID: 24466159
Journal: Int J Oncol. 2014 Apr;44(4):1341-8.
Title: Stimulation of beta-catenin and colon cancer cell growth by the KDM4B histone demethylase.
Author: Berry, William L|Kim, Tae-Dong|Janknecht, Ralf
PMID: 24481461
Journal: J Biol Chem. 2014 Mar 28;289(13):8881-90.
Title: Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer.
Author: Xu, Xuehe|Yu, Tianxin|Shi, Jiandang|Chen, Xi|Zhang, Wen|Lin, Ting|Liu, Zhihong|Wang, Yadong|Zeng, Zheng|Wang, Chi|Li, Mingsong|Liu, Chunming
PMID: 24532795
Journal: Nat Cell Biol. 2014 Mar;16(3):268-80.
Title: MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells.
Author: Hwang, Wei-Lun|Jiang, Jeng-Kae|Yang, Shung-Haur|Huang, Tse-Shun|Lan, Hsin-Yi|Teng, Hao-Wei|Yang, Chih-Yung|Tsai, Ya-Ping|Lin, Chi-Hung|Wang, Hsei-Wei|Yang, Muh-Hwa
PMID: 24561623
Journal: Pathol Oncol Res. 2014 Oct;20(4):847-51.
Title: HMGA1 interacts with beta-catenin to positively regulate Wnt/beta-catenin signaling in colorectal cancer cells.
Author: Xing, Junjie|Cao, Guangwen|Fu, Chuangang
PMID: 24696416
Journal: BMC Res Notes. 2014 Apr 9;7:226.
Title: Butyrate induced changes in Wnt-signaling specific gene expression in colorectal cancer cells.
Author: Lazarova, Darina L|Chiaro, Christopher|Bordonaro, Michael
PMID: 24716727
Journal: Int J Oncol. 2014 Jun;44(6):2077-84.
Title: HIF-1alpha activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.
Author: Nishimoto, Arata|Kugimiya, Naruji|Hosoyama, Tohru|Enoki, Tadahiko|Li, Tao-Sheng|Hamano, Kimikazu
PMID: 24718784
Journal: Gastroenterology. 2014 Aug;147(2):430-442.e8.
Title: ITF2 prevents activation of the beta-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.
Author: Shin, Hyun-Woo|Choi, Hyunsung|So, Daeho|Kim, Young-Im|Cho, Kumsun|Chung, Hee-Joon|Lee, Kyoung-Hwa|Chun, Yang-Sook|Cho, Chung-Hyun|Kang, Gyeong Hoon|Kim, Woo Ho|Park, Jong-Wan
PMID: 24846398
Journal: Anticancer Drugs. 2014 Sep;25(8):908-16.
Title: TCF4 silencing sensitizes the colon cancer cell line to oxaliplatin as a common chemotherapeutic drug.
Author: Gheidari, Fatemeh|Bakhshandeh, Behnaz|Teimoori-Toolabi, Ladan|Mehrtash, Amirhosein|Ghadir, Mahdis|Zeinali, Sirous
PMID: 24869759
Journal: Nat Cell Biol. 2014 Jul;16(7):695-707.
Title: The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.
Author: Whissell, Gavin|Montagni, Elisa|Martinelli, Paola|Hernando-Momblona, Xavier|Sevillano, Marta|Jung, Peter|Cortina, Carme|Calon, Alexandre|Abuli, Anna|Castells, Antoni|Castellvi-Bel, Sergi|Nacht, Ana Silvina|Sancho, Elena|Stephan-Otto Attolini, Camille|Vice
PMID: 24952462
Journal: Tumour Biol. 2014 Oct;35(10):10319-24.
Title: Oncogenicity of LHX4 in colorectal cancer through Wnt/beta-catenin/TCF4 cascade.
Author: Cha, Nier|Liu, Wei|Yang, Na|Xie, Shengzhi|Gao, Yanwei|Chen, Xia|Wang, Xiaoli|Ren, Jun
PMID: 25034524
Journal: FEBS Lett. 2014 Nov 28;588(23):4334-41.
Title: TRIB2 inhibits Wnt/beta-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, beta-TrCP, COP1 and Smurf1, in liver cancer cells.
Author: Xu, Shanshan|Tong, Minghong|Huang, Jingqin|Zhang, Yue|Qiao, Yongxia|Weng, Wenhao|Liu, Weiwei|Wang, Jiayi|Sun, Fenyong
PMID: 25311538
Journal: Int J Exp Pathol. 2014 Dec;95(6):392-400.
Title: STAT3 paradoxically stimulates beta-catenin expression but inhibits beta-catenin function.
Author: Ibrahem, Salih|Al-Ghamdi, Saleh|Baloch, Kanwal|Muhammad, Belal|Fadhil, Wakkas|Jackson, Darryl|Nateri, Abdolrahman S|Ilyas, Mohammad
PMID: 25348333
Journal: Int J Clin Exp Med. 2014 Nov 15;7(11):4253-9. eCollection 2014.
Title: Genome-wide ChIP-seq analysis of TCF4 binding regions in colorectal cancer cells.
Author: Chen, Chen|Lu, Yachun|Liu, Jie|Li, Lisha|Zhao, Na|Lin, Biaoyang
PMID: 25550940
Journal: Mol Carcinog. 2015 Sep;54(9):789-799.
Title: Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.
Author: Koneczny, Inga|Schulenburg, Axel|Hudec, Xenia|Knofler, Martin|Holzmann, Klaus|Piazza, Gary|Reynolds, Robert|Valent, Peter|Marian, Brigitte
PMID: 24619956
Journal: Mol Cell Biochem. 2015 Jan;399(1-2):1-5.
Title: Lhx3 is required to maintain cancer cell development of high-grade oligodendroglioma.
Author: Liu, Hongliang|Liu, Wei|Zhu, Bin|Xu, Qiang|Ni, Xiaowei|Yu, Ji
PMID: 25399296
Journal: Oncogene. 2015 Sep 17;34(38):4914-27.
Title: Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer.
Author: Lemieux, E|Cagnol, S|Beaudry, K|Carrier, J|Rivard, N
PMID: 25500543
Journal: Carcinogenesis. 2015 Mar;36(3):318-26.
Title: A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/beta-catenin signaling.
Author: Ye, Qi|Yao, Guangmin|Zhang, Mengke|Guo, Guoli|Hu, Yufeng|Jiang, Jue|Cheng, Ling|Shi, Jianguo|Li, Hua|Zhang, Yonghui|Liu, Hudan
PMID: 25600769
Journal: Cell Cycle. 2015;14(3):323-32.
Title: A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells.
Author: Shah, Meera|Rennoll, Sherri A|Raup-Konsavage, Wesley M|Yochum, Gregory S
PMID: 25659031
Journal: Cell Signal. 2015 May;27(5):961-8.
Title: Kruppel-like factor 5 incorporates into the beta-catenin/TCF complex in response to LPA in colon cancer cells.
Author: Guo, Leilei|He, Peijian|No, Yi Ran|Yun, C Chris
PMID: 25683913
Journal: Biochem Biophys Res Commun. 2015 May 29;461(2):249-53.
Title: Inactivation of Itf2 promotes intestinal tumorigenesis in Apc(Min/+) mice.
Author: Grill, Jessica I|Herbst, Andreas|Brandl, Lydia|Kong, Lixia|Schneider, Marlon R|Kirchner, Thomas|Wolf, Eckhard|Kolligs, Frank T
PMID: 25869068
Journal: Oncogenesis. 2015 Jun 15;4:e157.
Title: An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/beta-catenin-elicited promotion of the cancer stem cell phenotype.
Author: Su, Y-J|Chang, Y-W|Lin, W-H|Liang, C-L|Lee, J-L
PMID: 26075748
Journal: Oncotarget. 2015 Sep 29;6(29):28312-26.
Title: Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer.
Author: Heerma van Voss, Marise R|Vesuna, Farhad|Trumpi, Kari|Brilliant, Justin|Berlinicke, Cynthia|de Leng, Wendy|Kranenburg, Onno|Offerhaus, G Johan|Burger, Horst|van der Wall, Elsken|van Diest, Paul J|Raman, Venu
PMID: 26311743
Journal: Oncogene. 2015 Nov 12;34(46):5760-70.
Title: ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression.
Author: Sanchez-Tillo, E|de Barrios, O|Valls, E|Darling, D S|Castells, A|Postigo, A
PMID: 26387539
Journal: Asian Pac J Cancer Prev. 2015;16(15):6549-56.
Title: Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways.
Author: Wee, Lee Heng|Morad, Noor Azian|Aan, Goon Jo|Makpol, Suzana|Wan Ngah, Wan Zurinah|Mohd Yusof, Yasmin Anum
PMID: 26434873
Journal: Sci Rep. 2015 Oct 8;5:14983.
Title: Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications.
Author: O'Connell, Malaney R|Sarkar, Shubhashish|Luthra, Gurinder K|Okugawa, Yoshinaga|Toiyama, Yuji|Gajjar, Aakash H|Qiu, Suimin|Goel, Ajay|Singh, Pomila
PMID: 26447334
Journal: Biochem Biophys Res Commun. 2015 Nov 27;467(4):629-37.
Title: Rock2 stabilizes beta-catenin to promote tumor invasion and metastasis in colorectal cancer.
Author: Qiu, Yumin|Yuan, Rongfa|Zhang, Shouhua|Chen, Leifeng|Huang, Da|Hao, Haibin|Shao, Jianghua
PMID: 26505794
Journal: Mol Carcinog. 2016 May;55(5):411-9.
Title: LoVo colon cancer cells resistant to oxaliplatin overexpress c-MET and VEGFR-1 and respond to VEGF with dephosphorylation of c-MET.
Author: Mezquita, Belen|Pineda, Estela|Mezquita, Jovita|Mezquita, Pau|Pau, Montserrat|Codony-Servat, Jordi|Martinez-Balibrea, Eva|Mora, Conchi|Maurel, Joan|Mezquita, Cristobal
PMID: 25647613
Journal: J Steroid Biochem Mol Biol. 2016 Jan;155(Pt B):224-30.
Title: Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells.
Author: Groschel, Charlotte|Aggarwal, Abhishek|Tennakoon, Samawansha|Hobaus, Julia|Prinz-Wohlgenannt, Maximilian|Marian, Brigitte|Heffeter, Petra|Berger, Walter|Kallay, Eniko
PMID: 25777538
Journal: Gut. 2016 Oct;65(10):1690-701.
Title: New Wnt/beta-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Author: Qi, Jingjing|Yu, Yong|Akilli Ozturk, Ozlem|Holland, Jane D|Besser, Daniel|Fritzmann, Johannes|Wulf-Goldenberg, Annika|Eckert, Klaus|Fichtner, Iduna|Birchmeier, Walter
PMID: 26156959
Journal: Oncogene. 2016 Mar 31;35(13):1679-91.
Title: Wnt/beta-catenin signaling regulated SATB1 promotes colorectal cancer tumorigenesis and progression.
Author: Mir, R|Pradhan, S J|Patil, P|Mulherkar, R|Galande, S
PMID: 26165840
Journal: Gastroenterology. 2016 Mar;150(3):659-671.e16.
Title: OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.
Author: Ye, Guo-Dong|Sun, Guang-Bin|Jiao, Peng|Chen, Chen|Liu, Qing-Feng|Huang, Xiao-Li|Zhang, Rui|Cai, Wang-Yu|Li, Sheng-Nan|Wu, Jia-Fa|Liu, Yun-Jia|Wu, Rong-Si|Xie, Yuan-Yuan|Chan, Err-Cheng|Liou, Yih-Cherng|Li, Bo-An
PMID: 26619963
Journal: Cancer Res. 2016 Feb 15;76(4):891-901.
Title: A Small-Molecule Antagonist of the beta-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis.
Author: Fang, Liang|Zhu, Qionghua|Neuenschwander, Martin|Specker, Edgar|Wulf-Goldenberg, Annika|Weis, William I|von Kries, Jens P|Birchmeier, Walter
PMID: 26645562
Journal: BMC Cancer. 2016 Feb 17;16:113.
Title: Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients.
Author: Savio, Andrea J|Daftary, Darshana|Dicks, Elizabeth|Buchanan, Daniel D|Parfrey, Patrick S|Young, Joanne P|Weisenberger, Daniel|Green, Roger C|Gallinger, Steven|McLaughlin, John R|Knight, Julia A|Bapat, Bharati
PMID: 26884349
Journal: Oncogene. 2016 Sep 22;35(38):4990-9.
Title: Topoisomerase IIalpha mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.
Author: Zhou, Q|Abraham, A D|Li, L|Babalmorad, A|Bagby, S|Arcaroli, J J|Hansen, R J|Valeriote, F A|Gustafson, D L|Schaack, J|Messersmith, W A|LaBarbera, D V
PMID: 26947016
Journal: Cancer Cell Int. 2016 Mar 24;16:22.
Title: Time course analysis based on gene expression profile and identification of target molecules for colorectal cancer.
Author: Chen, Guoting|Han, Ning|Li, Guofeng|Li, Xin|Li, Guang|Li, Zengchun|Li, Qinchuan
PMID: 27013928
Journal: Biomol Ther (Seoul). 2016 Jul 1;24(4):380-6.
Title: Inhibition of Wnt Signaling by Silymarin in Human Colorectal Cancer Cells.
Author: Eo, Hyun Ji|Park, Gwang Hun|Jeong, Jin Boo
PMID: 27068260
Journal: Cell Rep. 2016 Jun 21;15(12):2588-96.
Title: A Positive Regulatory Loop between a Wnt-Regulated Non-coding RNA and ASCL2 Controls Intestinal Stem Cell Fate.
Author: Giakountis, Antonis|Moulos, Panagiotis|Zarkou, Vasiliki|Oikonomou, Christina|Harokopos, Vaggelis|Hatzigeorgiou, Artemis G|Reczko, Martin|Hatzis, Pantelis
PMID: 27292638
Journal: Cancer Res. 2016 Oct 1;76(19):5615-5627.
Title: RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells.
Author: Di Cecilia, Serena|Zhang, Fan|Sancho, Ana|Li, SiDe|Aguilo, Francesca|Sun, Yifei|Rengasamy, Madhumitha|Zhang, Weijia|Del Vecchio, Luigi|Salvatore, Francesco|Walsh, Martin J
PMID: 27520449
Journal: Mol Carcinog. 2017 Nov;56(11):2372-2381.
Title: Differential expression of LEF1/TCFs family members in colonic carcinogenesis.
Author: Han, Wenxiao|He, Longmei|Cao, Bangrong|Zhao, Xinhua|Zhang, Kaitai|Li, Yan|Beck, Paul|Zhou, Zhixiang|Tian, Yantao|Cheng, Shujun|Wang, Hongying
PMID: 27433921
Journal: Cancer Res. 2017 Jan 1;77(1):142-152.
Title: Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells.
Author: Kang, Dong Woo|Lee, Shin Wha|Hwang, Won Chan|Lee, Bo Hui|Choi, Yong-Seok|Suh, Young-Ah|Choi, Kang-Yell|Min, Do Sik
PMID: 27793841
Journal: Oncotarget. 2017 Feb 7;8(6):9783-9793.
Title: Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells.
Author: Dai, Yuedi|Wang, Meixing|Wu, Haixia|Xiao, Mi|Liu, Houbao|Zhang, Dexiang
PMID: 28039460
Journal: Nat Commun. 2017 Jan 4;8:14058.
Title: VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer.
Author: Jiao, Shi|Li, Chuanchuan|Hao, Qian|Miao, Haofei|Zhang, Lei|Li, Lin|Zhou, Zhaocai
PMID: 28051067
Journal: Mol Cancer. 2017 Jan 13;16(1):9.
Title: The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/beta-catenin signaling.
Author: Han, Peng|Li, Jing-Wen|Zhang, Bo-Miao|Lv, Jia-Chen|Li, Yong-Min|Gu, Xin-Yue|Yu, Zhi-Wei|Jia, Yun-He|Bai, Xue-Feng|Li, Li|Liu, Yan-Long|Cui, Bin-Bin
PMID: 28086904
Journal: Mol Cancer. 2017 Jan 31;16(1):20.
Title: Up-regulated NRIP2 in colorectal cancer initiating cells modulates the Wnt pathway by targeting RORbeta.
Author: Wen, Zhenzhen|Pan, Tianhui|Yang, Saisai|Liu, Jingwen|Tao, Haiying|Zhao, Yiming|Xu, Dingting|Shao, Wei|Wu, Jia|Liu, Xiyong|Wang, Yongjiang|Mao, Jianshan|Zhu, Yongliang
PMID: 28137278
Journal: Oncol Rep. 2017 Apr;37(4):2398-2404.
Title: USP39 promotes colorectal cancer growth and metastasis through the Wnt/beta-catenin pathway.
Author: Yuan, Xianwen|Sun, Xitai|Shi, Xiaolei|Wang, Hao|Wu, Guoyi|Jiang, Chunping|Yu, Decai|Zhang, Weiwei|Xue, Bin|Ding, Yitao
PMID: 28259917
Journal: Cell Rep. 2017 Apr 25;19(4):760-773.
Title: Environmental Enrichment Induces Pericyte and IgA-Dependent Wound Repair and Lifespan Extension in a Colon Tumor Model.
Author: Bice, Benjamin D|Stephens, Megan R|Georges, Stephanie J|Venancio, Ashlee R|Bermant, Peter C|Warncke, Annika V|Affolter, Kajsa E|Hidalgo, Julio R|Angus-Hill, Melinda L
PMID: 28445727
Journal: Exp Biol Med (Maywood). 2017 Jun;242(11):1185-1197.
Title: Discovery of small molecule inhibitors of the Wnt/beta-catenin signaling pathway by targeting beta-catenin/Tcf4 interactions.
Author: Yan, Maocai|Li, Guanqun|An, Jing
PMID: 28474989
Journal: Clin Cancer Res. 2017 Sep 1;23(17):5267-5280.
Title: Targeting the Wnt Pathway and Cancer Stem Cells with Anti-progastrin Humanized Antibodies as a Potential Treatment for K-RAS-Mutated Colorectal Cancer.
Author: Prieur, Alexandre|Cappellini, Monica|Habif, Guillaume|Lefranc, Marie-Paule|Mazard, Thibault|Morency, Eric|Pascussi, Jean-Marc|Flaceliere, Maud|Cahuzac, Nathalie|Vire, Berengere|Dubuc, Benjamin|Durochat, Amandine|Liaud, Pierre|Ollier, Jeremy|Pfeiffer, Caro
PMID: 28600477
Journal: BMC Complement Altern Med. 2017 Sep 5;17(1):445.
Title: Anticancer activity of calyx of Diospyros kaki Thunb. through downregulation of cyclin D1 via inducing proteasomal degradation and transcriptional inhibition in human colorectal cancer cells.
Author: Park, Su Bin|Park, Gwang Hun|Song, Hun Min|Son, Ho-Jun|Um, Yurry|Kim, Hyun-Seok|Jeong, Jin Boo
PMID: 28870200
Journal: Cancer Res. 2017 Dec 1;77(23):6562-6575.
Title: DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer.
Author: Huang, Shuo|Fantini, Damiano|Merrill, Bradley J|Bagchi, Srilata|Guzman, Grace|Raychaudhuri, Pradip
PMID: 29021137
Journal: Front Pharmacol. 2017 Nov 24;8:877.
Title: Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/beta-Catenin Pathways via miR-130a.
Author: Dou, Huiqiang|Shen, Renhui|Tao, Jianxin|Huang, Longchang|Shi, Haoze|Chen, Hang|Wang, Yixin|Wang, Tong
PMID: 29225578
Journal: Oncotarget. 2017 Nov 1;8(60):102176-102190.
Title: Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis.
Author: Wang, Xingmin|Yang, Yonghong|Huycke, Mark M
PMID: 29254234
Journal: Oncotarget. 2017 Dec 4;8(67):111715-111727.
Title: Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/beta-catenin signaling pathway.
Author: Zhu, Yuping|Li, Bo|Liu, Zhuo|Jiang, Lai|Wang, Gang|Lv, Min|Li, Dechuan
PMID: 29340086
Journal: J Cell Biochem. 2018 Feb;119(2):2022-2035.
Title: microRNA-145 downregulates SIP1-expression but differentially regulates proliferation, migration, invasion and Wnt signaling in SW480 and SW620 cells.
Author: Sathyanarayanan, Anusha|Chandrasekaran, Karthik Subramanian|Karunagaran, Devarajan
PMID: 28833449
Journal: Int J Cancer. 2018 Jan 15;142(2):308-321.
Title: Tumor-suppressive miR-145 co-repressed by TCF4-beta-catenin and PRC2 complexes forms double-negative regulation loops with its negative regulators in colorectal cancer.
Author: Wang, Wei|Xiao, Xin|Chen, Xu|Huo, Yi|Xi, Wen-Jin|Lin, Zhi-Feng|Zhang, Dan|Li, Yu-Fang|Yang, Fan|Wen, Wei-Hong|Yang, An-Gang|Wang, Tao
PMID: 28921929
Journal: J Proteome Res. 2018 Jan 5;17(1):252-264.
Title: Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer.
Author: Torres, Sofia|Garcia-Palmero, Irene|Marin-Vicente, Consuelo|Bartolome, Ruben A|Calvino, Eva|Fernandez-Acenero, Maria Jesus|Casal, J Ignacio
PMID: 29131639
Journal: Am J Chin Med. 2018;46(1):191-207.
Title: Vitex rotundifolia Fruit Suppresses the Proliferation of Human Colorectal Cancer Cells through Down-regulation of Cyclin D1 and CDK4 via Proteasomal-Dependent Degradation and Transcriptional Inhibition.
Author: Song, Hun Min|Park, Gwang Hun|Park, Su Bin|Kim, Hyun-Seok|Son, Ho-Jun|Um, Yurry|Jeong, Jin Boo
PMID: 29298515
Journal: Oncol Res. 2018 Jan 4.
Title: Emodin inhibits colon cancer cell invasion and migration by suppressing epithelialmesenchymal transition via the Wnt/beta-catenin pathway.
Author: Gu, Juan|Cui, Chang-Fu|Yang, Li|Wang, Ling|Jiang, Xue-Hua
PMID: 29301594
Journal: Sci Rep. 2018 Jan 12;8(1):671.
Title: Beta-catenin cleavage enhances transcriptional activation.
Author: Goretsky, Tatiana|Bradford, Emily M|Ye, Qing|Lamping, Olivia F|Vanagunas, Tomas|Moyer, Mary Pat|Keller, Patrick C|Sinh, Preetika|Llovet, Josep M|Gao, Tianyan|She, Qing-Bai|Li, Linheng|Barrett, Terrence A
PMID: 29330435
Journal: Cancer Res. 2018 Apr 15;78(8):1958-1971.
Title: RNF6 Promotes Colorectal Cancer by Activating the Wnt/beta-Catenin Pathway via Ubiquitination of TLE3.
Author: Liu, Lei|Zhang, Yanquan|Wong, Chi Chun|Zhang, Jingwan|Dong, Yujuan|Li, Xiangchun|Kang, Wei|Chan, Francis K L|Sung, Joseph J Y|Yu, Jun
PMID: 29374067
Journal: J Biomol Struct Dyn. 2018 Mar 12:1-15.
Title: Molecular dynamics of interaction of Sesamin and related compounds with the cancer marker beta-catenin: an in silico study.
Author: Cavuturu, Bindu Madhuri|Bhandare, Vishwambar Vishnu|Ramaswamy, Amutha|Arumugam, Neelakantan
PMID: 29455637
Journal: PLoS One. 2018 Feb 20;13(2):e0192958.
Title: Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence.
Author: Marcuello, Maria|Mayol, Xavier|Felipe-Fumero, Eloisa|Costa, Jaume|Lopez-Hierro, Laia|Salvans, Silvia|Alonso, Sandra|Pascual, Marta|Grande, Luis|Pera, Miguel
PMID: 29462209
Journal: Oncogene. 2018 Jun;37(24):3301-3316.
Title: beta-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy.
Author: Saponaro, Concetta|Sergio, Sara|Coluccia, Antonio|De Luca, Maria|La Regina, Giuseppe|Mologni, Luca|Famiglini, Valeria|Naccarato, Valentina|Bonetti, Daniela|Gautier, Candice|Gianni, Stefano|Vergara, Daniele|Salzet, Michel|Fournier, Isabelle|Bucci, Cecilia|
PMID: 29551770
Journal: BMC Complement Altern Med. 2018 Jan 25;18(1):28.
Title: Cytotoxic activity of the twigs of Cinnamomum cassia through the suppression of cell proliferation and the induction of apoptosis in human colorectal cancer cells.
Author: Park, Gwang Hun|Song, Hun Min|Park, Su Bin|Son, Ho-Jun|Um, Yurry|Kim, Hyun-Seok|Jeong, Jin Boo
PMID: 29554905
Journal: Oncol Lett. 2018 Jun;15(6):8744-8748.
Title: miR-137 suppresses proliferation, migration and invasion of colon cancer cell lines by targeting TCF4.
Author: Bi, Wei-Ping|Xia, Min|Wang, Xin-Jian
PMID: 29805612
Journal: PLoS One. 2018 Jul 2;13(7):e0194160.
Title: The stress response gene ATF3 is a direct target of the Wnt/beta-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells.
Author: Inoue, Makoto|Uchida, Yohei|Edagawa, Makoto|Hirata, Manabu|Mitamura, Jun|Miyamoto, Daiki|Taketani, Kenji|Sekine, Shigeki|Kawauchi, Junya|Kitajima, Shigetaka
PMID: 29966001
Journal: PLoS One. 2018 Jul 5;13(7):e0200215.
Title: The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2.
Author: Davidsen, Johanne|Larsen, Sylvester|Coskun, Mehmet|Gogenur, Ismail|Dahlgaard, Katja|Bennett, Eric Paul|Troelsen, Jesper Thorvald
PMID: 29975781
Journal: Stem Cell Reports. 2018 Aug 14;11(2):410-424.
Title: The Zinc Finger Transcription Factor PLAGL2 Enhances Stem Cell Fate and Activates Expression of ASCL2 in Intestinal Epithelial Cells.
Author: Strubberg, Ashlee M|Veronese Paniagua, Daniel A|Zhao, Tingting|Dublin, Leeran|Pritchard, Thomas|Bayguinov, Peter O|Fitzpatrick, James A J|Madison, Blair B
PMID: 30017821
Journal: Mol Cancer Res. 2018 Aug 2. pii: 1541-7786.MCR-18-0115.
Title: miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.
Author: Prossomariti, Anna|Piazzi, Giulia|D'Angelo, Leonarda|Miccoli, Sara|Turchetti, Daniela|Alquati, Chiara|Montagna, Claudio|Bazzoli, Franco|Ricciardiello, Luigi
PMID: 30072583
Journal: Mol Cancer Res. 2018 Aug 10. pii: 1541-7786.MCR-18-0262.
Title: FLYWCH1, a Novel Suppressor of Nuclear beta-Catenin, Regulates Migration and Morphology in Colorectal Cancer.
Author: Muhammad, Belal A|Almozyan, Sheema|Babaei-Jadidi, Roya|Onyido, Emenike K|Saadeddin, Anas|Kashfi, Seyed Hossein|Spencer-Dene, Bradley|Ilyas, Mohammad|Lourdusamy, Anbarasu|Behrens, Axel|Nateri, Abdolrahman S
PMID: 30097457
Journal: Exp Mol Med. 2018 Aug 14;50(8):101.
Title: Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells.
Author: He, Lingfeng|Zhu, Hong|Zhou, Shiying|Wu, Ting|Wu, Huan|Yang, Huan|Mao, Huiwen|SekharKathera, Chandra|Janardhan, Avilala|Edick, Ashlin M|Zhang, Anna|Hu, Zhigang|Pan, Feiyan|Guo, Zhigang
PMID: 30111797
Journal: Int J Mol Sci. 2018 Aug 16;19(8). pii: ijms19082427.
Title: Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1.
Author: Hsu, Ya-Ling|Chen, Yi-Jen|Chang, Wei-An|Jian, Shu-Fang|Fan, Hsiao-Li|Wang, Jaw-Yuan|Kuo, Po-Lin
PMID: 30115896
Journal: J Agric Food Chem. 2018 Sep 19;66(37):9635-9644.
Title: Cell Motility Facilitated by Mono(2-ethylhexyl) Phthalate via Activation of the AKT-beta-Catenin-IL-8 Axis in Colorectal Cancer.
Author: Luo, Chi-Wen|Hsiao, I-Ling|Wang, Jaw-Yuan|Wu, Chun-Chieh|Hung, Wen-Chun|Lin, Yu-Han|Chen, Tzu-Yi|Hsu, Yin-Chou|Cheng, Tian-Lu|Pan, Mei-Ren
PMID: 30188700
Journal: J Exp Clin Cancer Res. 2018 Sep 25;37(1):238.
Title: MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/beta-catenin positive feedback loop.
Author: Li, Tingting|Jian, Xiangyu|He, Han|Lai, Qiuhua|Li, Xianzheng|Deng, Danling|Liu, Tengfei|Zhu, Jiehong|Jiao, Hongli|Ye, Yaping|Wang, Shuyang|Yang, Minhui|Zheng, Lin|Zhou, Weijie|Ding, Yanqing
PMID: 30253791
Journal: Oncotarget. 2018 Sep 21;9(74):33982-33994.
Title: Sulforaphane inhibits growth and blocks Wnt/beta-catenin signaling of colorectal cancer cells.
Author: Bernkopf, Dominic B|Daum, Gabriele|Bruckner, Martina|Behrens, Jurgen
PMID: 30338040
Journal: Gastroenterology. 2018 Oct 23. pii: S0016-5085(18)35163-1.
Title: TRIB3 Interacts with Beta-catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
Author: Hua, Fang|Shang, Shuang|Yang, Yu-Wei|Zhang, Hai-Zeng|Xu, Tian-Lei|Yu, Jiao-Jiao|Zhou, Dan-Dan|Cui, Bing|Li, Ke|Lv, Xiao-Xi|Zhang, Xiao-Wei|Liu, Shan-Shan|Yu, Jin-Mei|Wang, Feng|Zhang, Cheng|Huang, Bo|Hu, Zhuo-Wei
PMID: 30365932
Journal: Carcinogenesis. 2018 Oct 31. pii: 5149556.
Title: Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells.
Author: Neumeyer, Victoria|Grandl, Martina|Dietl, Alisa|Brutau-Abia, Anna|Allgauer, Michael|Kalali, Behnam|Zhang, Yang|Pan, Kai-Feng|Steiger, Katja|Vieth, Michael|Anton, Martina|Mejias-Luque, Raquel|Gerhard, Markus
PMID: 30380024