Primary Site >> Colorectal Cancer
Gene >> TCF4
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Ref: [beta-catenin overexpression in metastasized colorectal carcinoma--an important mechanism in progression of the disease?]. PMID: 14518265 |
Ref: Identification of Tcf4 residues involved in high-affinity beta-catenin binding. PMID: 10080941 |
Ref: Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation. PMID: 10918391 Ref: Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis. PMID: 10987283 Ref: [beta-Catenin induces invasive growth by activating matrix metalloproteinases in colorectal carcinoma]. PMID: 11217438 |
Ref: A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics. PMID: 11221869 Ref: Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway. PMID: 11222711 Ref: Restoration of epithelial cell polarity in a colorectal cancer cell line by suppression of beta-catenin/T-cell factor 4-mediated gene transactivation. PMID: 11289158 Ref: Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. PMID: 11326276 Ref: Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. PMID: 11470825 Ref: Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma. PMID: 11572874 Ref: Tcf4 can specifically recognize beta-catenin using alternative conformations. PMID: 11713475 |
Ref: Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. PMID: 11774242 Ref: Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. PMID: 11943708 Ref: Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability. PMID: 11980438 Ref: Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer. PMID: 11996796 Ref: Stimulation of Cdx1 by oncogenic beta-catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein. PMID: 11997022 Ref: Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. PMID: 12384519 Ref: Short chain fatty acids and colon cancer. PMID: 12468628 Ref: Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. PMID: 12481159 |
Ref: Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy. PMID: 12533679 Ref: Exclusion of Madh2, Madh4, and Madh7 as candidates for the modifier of Min 2 (Mom2) locus. PMID: 12584607 Ref: The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway. PMID: 12651860 Ref: Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. PMID: 12776180 Ref: Wnt signaling during development of the gastrointestinal tract. PMID: 12871700 Ref: Overexpression of the beta-catenin binding domain of cadherin selectively kills colorectal cancer cells. PMID: 12949799 Ref: Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex. PMID: 14559787 Ref: TIP49 regulates beta-catenin-mediated neoplastic transformation and T-cell factor target gene induction via effects on chromatin remodeling. PMID: 14695187 |
Ref: Wnt breakers in colon cancer. PMID: 14749120 Ref: Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation. PMID: 14770182 Ref: Dietary soy sphingolipids suppress tumorigenesis and gene expression in 1,2-dimethylhydrazine-treated CF1 mice and ApcMin/+ mice. PMID: 15113963 Ref: Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate. PMID: 15122584 Ref: Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells. PMID: 15141037 Ref: [Indomethacin induces apoptosis through inhibition of survivin regulated by beta-catenin/TCF4 in human colorectal cancer cells]. PMID: 15248904 |
Ref: beta-Catenin activates the growth factor endothelin-1 in colon cancer cells. PMID: 15558022 Ref: The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. PMID: 15592505 Ref: Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3). PMID: 15695391 Ref: Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine. PMID: 15716339 Ref: Wnt signalling induces maturation of Paneth cells in intestinal crypts. PMID: 15778706 Ref: The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway. PMID: 15853773 Ref: Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: effects on proliferation, differentiation, and gene expression. PMID: 15935729 Ref: The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesis. PMID: 15972967 Ref: EphB receptor activity suppresses colorectal cancer progression. PMID: 15973414 |
Ref: Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours. PMID: 16272170 Ref: Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis. PMID: 16407833 Ref: Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer. PMID: 16421660 Ref: APC inhibits ERK pathway activation and cellular proliferation induced by RAS. PMID: 16478791 Ref: SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling. PMID: 16489032 Ref: Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells. PMID: 16569639 Ref: Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development. PMID: 16885356 Ref: Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc. PMID: 16954380 Ref: Colorectal cancer and genetic alterations in the Wnt pathway. PMID: 17143297 |
Ref: An antisense transcript induced by Wnt/beta-catenin signaling decreases E2F4. PMID: 17121828 Ref: The Intestinal Wnt/TCF Signature. PMID: 17320548 Ref: Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells. PMID: 17360646 Ref: CBP/p300 are bimodal regulators of Wnt signaling. PMID: 17410209 Ref: Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling. PMID: 17634137 Ref: EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells. PMID: 17906625 |
Ref: Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. PMID: 18268006 Ref: Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. PMID: 18451518 Ref: Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival. PMID: 18465804 Ref: The ubiquitin-proteasome system in colorectal cancer. PMID: 18619533 Ref: RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis. PMID: 18772112 Ref: A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. PMID: 18852287 Ref: KLF4 regulation in intestinal epithelial cell maturation. PMID: 18977346 Ref: Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors. PMID: 18992165 Ref: Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine. PMID: 19075513 |
Ref: p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors. PMID: 18951899 Ref: The Bcl-w promoter is activated by beta-catenin/TCF4 in human colorectal carcinoma cells. PMID: 19124064 Ref: Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. PMID: 19190323 Ref: ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition. PMID: 19394332 Ref: Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer. PMID: 19421758 Ref: The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. PMID: 19561604 Ref: Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. PMID: 19602482 Ref: c-Rel is a transcriptional repressor of EPHB2 in colorectal cancer. PMID: 19621336 Ref: The transcription factor ITF-2A induces cell cycle arrest via p21(Cip1). PMID: 19635457 Ref: The NF-kappaB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1beta. PMID: 19779850 Ref: The kinase TNIK is an essential activator of Wnt target genes. PMID: 19816403 |
Ref: Downregulation of E-cadherin is an essential event in activating beta-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells. PMID: 19784072 Ref: KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin. PMID: 19901072 Ref: Total synthesis of (+)-A83586C, (+)-kettapeptin and (+)-azinothricin: powerful new inhibitors of beta-catenin/TCF4- and E2F-mediated gene transcription. PMID: 20405066 Ref: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells. PMID: 20428782 Ref: The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors. PMID: 20459822 Ref: Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq. PMID: 20460455 Ref: Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth. PMID: 20530691 Ref: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. PMID: 20696899 Ref: NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer. PMID: 20705583 Ref: Colorectal tumors are effectively eradicated by combined inhibition of {beta}-catenin, KRAS, and the oncogenic transcription factor ITF2. PMID: 20823162 Ref: LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer. PMID: 21092222 Ref: The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis. PMID: 21103407 |
Ref: Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway. PMID: 20938052 Ref: A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis. PMID: 21321609 Ref: T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. PMID: 21383188 Ref: Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet. PMID: 21406606 Ref: A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors. PMID: 21436631 Ref: Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4). PMID: 21454679 Ref: The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways. PMID: 21473864 Ref: Multiple Wnt/ss-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops. PMID: 21533051 Ref: COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status. PMID: 21668942 Ref: Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. PMID: 21892161 Ref: Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy. PMID: 21983179 Ref: beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. PMID: 22080605 |
Ref: The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling. PMID: 21873734 Ref: Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer. PMID: 21956205 Ref: Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes. PMID: 21963845 Ref: beta-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells. PMID: 22082586 Ref: P-21 activated kinase 1 knockdown inhibits beta-catenin signalling and blocks colorectal cancer growth. PMID: 22100495 Ref: VDR/RXR and TCF4/beta-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression. PMID: 22108803 Ref: Structure-based discovery of a novel inhibitor targeting the beta-catenin/Tcf4 interaction. PMID: 22224445 Ref: Design, synthesis, and biological evaluation of new diaminoquinazolines as beta-catenin/Tcf4 pathway inhibitors. PMID: 22229647 Ref: Wnt/beta-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells. PMID: 22337891 Ref: Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging. PMID: 22465936 Ref: MENA is a transcriptional target of the Wnt/beta-catenin pathway. PMID: 22615875 Ref: Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins. PMID: 22617424 Ref: The beta-catenin/TCF complex as a novel target of resveratrol in the Wnt/beta-catenin signaling pathway. PMID: 22935447 Ref: Activating mutations in beta-catenin in colon cancer cells alter their interaction with macrophages; the role of snail. PMID: 23029025 Ref: Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. PMID: 23251453 |
Ref: Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. PMID: 23232060 Ref: ZEB1 Promotes invasiveness of colorectal carcinoma cells through the opposing regulation of uPA and PAI-1. PMID: 23340304 Ref: Crosstalk between Wnt Signaling and RNA Processing in Colorectal Cancer. PMID: 23386908 Ref: Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis. PMID: 23722564 Ref: Henryin, an ent-kaurane diterpenoid, inhibits Wnt signaling through interference with beta-catenin/TCF4 interaction in colorectal cancer cells. PMID: 23844215 Ref: Modulation of beta-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. PMID: 24324366 |
Ref: Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer. PMID: 24390711 Ref: Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. PMID: 24413017 Ref: Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene. PMID: 24466159 Ref: Stimulation of beta-catenin and colon cancer cell growth by the KDM4B histone demethylase. PMID: 24481461 Ref: Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer. PMID: 24532795 Ref: MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. PMID: 24561623 Ref: HMGA1 interacts with beta-catenin to positively regulate Wnt/beta-catenin signaling in colorectal cancer cells. PMID: 24696416 Ref: Butyrate induced changes in Wnt-signaling specific gene expression in colorectal cancer cells. PMID: 24716727 Ref: HIF-1alpha activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells. PMID: 24718784 Ref: ITF2 prevents activation of the beta-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression. PMID: 24846398 Ref: TCF4 silencing sensitizes the colon cancer cell line to oxaliplatin as a common chemotherapeutic drug. PMID: 24869759 Ref: The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression. PMID: 24952462 Ref: Oncogenicity of LHX4 in colorectal cancer through Wnt/beta-catenin/TCF4 cascade. PMID: 25034524 Ref: TRIB2 inhibits Wnt/beta-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, beta-TrCP, COP1 and Smurf1, in liver cancer cells. PMID: 25311538 Ref: STAT3 paradoxically stimulates beta-catenin expression but inhibits beta-catenin function. PMID: 25348333 Ref: Genome-wide ChIP-seq analysis of TCF4 binding regions in colorectal cancer cells. PMID: 25550940 |
Ref: Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells. PMID: 24619956 Ref: Lhx3 is required to maintain cancer cell development of high-grade oligodendroglioma. PMID: 25399296 Ref: Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer. PMID: 25500543 Ref: A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/beta-catenin signaling. PMID: 25600769 Ref: A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells. PMID: 25659031 Ref: Kruppel-like factor 5 incorporates into the beta-catenin/TCF complex in response to LPA in colon cancer cells. PMID: 25683913 Ref: Inactivation of Itf2 promotes intestinal tumorigenesis in Apc(Min/+) mice. PMID: 25869068 Ref: An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/beta-catenin-elicited promotion of the cancer stem cell phenotype. PMID: 26075748 Ref: Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer. PMID: 26311743 Ref: ZEB1 and TCF4 reciprocally modulate their transcriptional activities to regulate Wnt target gene expression. PMID: 26387539 Ref: Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways. PMID: 26434873 Ref: Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications. PMID: 26447334 Ref: Rock2 stabilizes beta-catenin to promote tumor invasion and metastasis in colorectal cancer. PMID: 26505794 |
Ref: LoVo colon cancer cells resistant to oxaliplatin overexpress c-MET and VEGFR-1 and respond to VEGF with dephosphorylation of c-MET. PMID: 25647613 Ref: Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells. PMID: 25777538 Ref: New Wnt/beta-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals. PMID: 26156959 Ref: Wnt/beta-catenin signaling regulated SATB1 promotes colorectal cancer tumorigenesis and progression. PMID: 26165840 Ref: OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors. PMID: 26619963 Ref: A Small-Molecule Antagonist of the beta-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. PMID: 26645562 Ref: Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients. PMID: 26884349 Ref: Topoisomerase IIalpha mediates TCF-dependent epithelial-mesenchymal transition in colon cancer. PMID: 26947016 Ref: Time course analysis based on gene expression profile and identification of target molecules for colorectal cancer. PMID: 27013928 Ref: Inhibition of Wnt Signaling by Silymarin in Human Colorectal Cancer Cells. PMID: 27068260 Ref: A Positive Regulatory Loop between a Wnt-Regulated Non-coding RNA and ASCL2 Controls Intestinal Stem Cell Fate. PMID: 27292638 Ref: RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells. PMID: 27520449 |
Ref: Differential expression of LEF1/TCFs family members in colonic carcinogenesis. PMID: 27433921 Ref: Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells. PMID: 27793841 Ref: Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells. PMID: 28039460 Ref: VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer. PMID: 28051067 Ref: The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/beta-catenin signaling. PMID: 28086904 Ref: Up-regulated NRIP2 in colorectal cancer initiating cells modulates the Wnt pathway by targeting RORbeta. PMID: 28137278 Ref: USP39 promotes colorectal cancer growth and metastasis through the Wnt/beta-catenin pathway. PMID: 28259917 Ref: Environmental Enrichment Induces Pericyte and IgA-Dependent Wound Repair and Lifespan Extension in a Colon Tumor Model. PMID: 28445727 Ref: Discovery of small molecule inhibitors of the Wnt/beta-catenin signaling pathway by targeting beta-catenin/Tcf4 interactions. PMID: 28474989 Ref: Targeting the Wnt Pathway and Cancer Stem Cells with Anti-progastrin Humanized Antibodies as a Potential Treatment for K-RAS-Mutated Colorectal Cancer. PMID: 28600477 Ref: Anticancer activity of calyx of Diospyros kaki Thunb. through downregulation of cyclin D1 via inducing proteasomal degradation and transcriptional inhibition in human colorectal cancer cells. PMID: 28870200 Ref: DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer. PMID: 29021137 Ref: Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/beta-Catenin Pathways via miR-130a. PMID: 29225578 Ref: Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis. PMID: 29254234 Ref: Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/beta-catenin signaling pathway. PMID: 29340086 |
Ref: microRNA-145 downregulates SIP1-expression but differentially regulates proliferation, migration, invasion and Wnt signaling in SW480 and SW620 cells. PMID: 28833449 Ref: Tumor-suppressive miR-145 co-repressed by TCF4-beta-catenin and PRC2 complexes forms double-negative regulation loops with its negative regulators in colorectal cancer. PMID: 28921929 Ref: Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer. PMID: 29131639 Ref: Vitex rotundifolia Fruit Suppresses the Proliferation of Human Colorectal Cancer Cells through Down-regulation of Cyclin D1 and CDK4 via Proteasomal-Dependent Degradation and Transcriptional Inhibition. PMID: 29298515 Ref: Emodin inhibits colon cancer cell invasion and migration by suppressing epithelialmesenchymal transition via the Wnt/beta-catenin pathway. PMID: 29301594 Ref: Beta-catenin cleavage enhances transcriptional activation. PMID: 29330435 Ref: RNF6 Promotes Colorectal Cancer by Activating the Wnt/beta-Catenin Pathway via Ubiquitination of TLE3. PMID: 29374067 Ref: Molecular dynamics of interaction of Sesamin and related compounds with the cancer marker beta-catenin: an in silico study. PMID: 29455637 Ref: Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence. PMID: 29462209 Ref: beta-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy. PMID: 29551770 Ref: Cytotoxic activity of the twigs of Cinnamomum cassia through the suppression of cell proliferation and the induction of apoptosis in human colorectal cancer cells. PMID: 29554905 Ref: miR-137 suppresses proliferation, migration and invasion of colon cancer cell lines by targeting TCF4. PMID: 29805612 Ref: The stress response gene ATF3 is a direct target of the Wnt/beta-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells. PMID: 29966001 Ref: The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2. PMID: 29975781 Ref: The Zinc Finger Transcription Factor PLAGL2 Enhances Stem Cell Fate and Activates Expression of ASCL2 in Intestinal Epithelial Cells. PMID: 30017821 Ref: miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4. PMID: 30072583 Ref: FLYWCH1, a Novel Suppressor of Nuclear beta-Catenin, Regulates Migration and Morphology in Colorectal Cancer. PMID: 30097457 Ref: Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells. PMID: 30111797 Ref: Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1. PMID: 30115896 Ref: Cell Motility Facilitated by Mono(2-ethylhexyl) Phthalate via Activation of the AKT-beta-Catenin-IL-8 Axis in Colorectal Cancer. PMID: 30188700 Ref: MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/beta-catenin positive feedback loop. PMID: 30253791 Ref: Sulforaphane inhibits growth and blocks Wnt/beta-catenin signaling of colorectal cancer cells. PMID: 30338040 Ref: TRIB3 Interacts with Beta-catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis. PMID: 30365932 Ref: Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells. PMID: 30380024 |