Primary Site >> Liver Cancer

Gene >> TBC1D9

Journal: Mol Cell Biol. 1990 Nov;10(11):5728-35.
Title: Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas.
Author: Teeter, L D|Becker, F F|Chisari, F V|Li, D J|Kuo, M T
PMID: 2122232
Journal: J Cell Sci. 1991 Mar;98 ( Pt 3):317-22.
Title: Human hepatocellular carcinoma cell lines exhibit multidrug resistance unrelated to MRD1 gene expression.
Author: Shen, D W|Lu, Y G|Chin, K V|Pastan, I|Gottesman, M M
PMID: 1676033
Journal: Cell Growth Differ. 1992 Aug;3(8):531-40.
Title: Activation of multidrug resistance (P-glycoprotein) mdr3/mdr1a gene during the development of hepatocellular carcinoma in hepatitis B virus transgenic mice.
Author: Kuo, M T|Zhao, J Y|Teeter, L D|Ikeguchi, M|Chisari, F V
PMID: 1356418
Journal: J Surg Oncol. 1993 Jan;52(1):21-5.
Title: P-glycoprotein expression in hepatocellular carcinoma.
Author: Isshiki, K|Nakao, A|Ito, M|Hamaguchi, M|Takagi, H
PMID: 8095077
Journal: J Hepatol. 1993 Jun;18(2):168-72.
Title: MDR1 (multidrug resistance) gene expression in human primary liver cancer and cirrhosis.
Author: Chenivesse, X|Franco, D|Brechot, C
PMID: 8409332
Journal: Int J Oncol. 1993 Jun;2(6):1013-5.
Title: Effects of hyperthermia on multidrug-resistant human hepatocellular-carcinoma.
Author: Hata, Y|Takada, N|Sasaki, F|Ishimura, H|Wakisaka, Y|Hamada, H|Namieno, T|Takahashi, H|Une, Y|Uchino, J
PMID: 21573662
Journal: Eur J Biochem. 1994 Jan 15;219(1-2):521-8.
Title: Constitutive expression of functional P-glycoprotein in rat hepatoma cells.
Author: Fardel, O|Loyer, P|Lecureur, V|Glaise, D|Guillouzo, A
PMID: 7905826
Journal: J Natl Cancer Inst. 1994 May 4;86(9):700-5.
Title: MDR1 gene expression: its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines.
Author: Park, J G|Lee, S K|Hong, I G|Kim, H S|Lim, K H|Choe, K J|Kim, W H|Kim, Y I|Tsuruo, T|Gottesman, M M
PMID: 7908989
Journal: Cancer Metastasis Rev. 1994 Jun;13(2):209-22.
Title: Modulation of tumor cell response to chemotherapy by the organ environment.
Author: Fidler, I J|Wilmanns, C|Staroselsky, A|Radinsky, R|Dong, Z|Fan, D
PMID: 7923551
Journal: J Pharmacol Exp Ther. 1995 Nov;275(2):1011-8.
Title: Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.
Author: Schuetz, E G|Furuya, K N|Schuetz, J D
PMID: 7473127
Journal: FEBS Lett. 1995 Jul 17;368(2):373-6.
Title: Cell-specific effects of RAS oncogene and protein kinase C agonist TPA on P-glycoprotein function.
Author: Stromskaya, T P|Grigorian, I A|Ossovskaya, V S|Rybalkina, E Y|Chumakov, P M|Kopnin, B P
PMID: 7628641
Journal: Br J Cancer. 1995 Apr;71(4):676-83.
Title: Characterisation of high-level cisplatin-resistant cell lines established from a human hepatoma cell line and human KB adenocarcinoma cells: cross-resistance and protein changes.
Author: Shen, D W|Akiyama, S|Schoenlein, P|Pastan, I|Gottesman, M M
PMID: 7710928
Journal: Hepatology. 1996 Apr;23(4):662-8.
Title: Overexpression of a p-glycoprotein in hepatocellular carcinomas from woodchuck hepatitis virus-infected woodchucks (Marmota monax).
Author: Dunn, S E|Hughes, C S|LeBlanc, G A|Cullen, J M
PMID: 8666315
Journal: Biochem Pharmacol. 1996 Jul 12;52(1):127-31.
Title: Expression of the low-density lipoprotein receptor, HMG-CoA reductase, and multidrug resistance (Mdr1) genes in colorectal carcinomas.
Author: Vitols, S|Gunven, P|Gruber, A|Larsson, O
PMID: 8678896
Journal: J Clin Pathol. 1996 Jun;49(6):470-3.
Title: Expression of P-glycoprotein in hepatocellular carcinoma: a potential marker of prognosis.
Author: Soini, Y|Virkajarvi, N|Raunio, H|Paakko, P
PMID: 8763260
Journal: Cancer Res. 1997 Sep 1;57(17):3708-16.
Title: Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis.
Author: Furuya, K N|Bradley, G|Sun, D|Schuetz, E G|Schuetz, J D
PMID: 9288777
Journal: Hepatology. 1997 Nov;26(5):1195-202.
Title: Effect of a xanthine analog on human hepatocellular carcinoma cells (Alexander) in culture and in xenografts in SCID mice.
Author: Marucci, L|Varticovski, L|Arias, I M
PMID: 9362362
Journal: J Hepatol. 1998 Dec;29(6):872-8.
Title: Transactivation of the human MDR1 gene by hepatitis B virus X gene product.
Author: Doong, S L|Lin, M H|Tsai, M M|Li, T R|Chuang, S E|Cheng, A L
PMID: 9875632
Journal: Int J Oncol. 1999 Sep;15(3):559-63.
Title: Overexpression of multidrug resistance genes MDR1 and cMOAT in human hepatocellular carcinoma and hepatoblastoma cell lines.
Author: Minemura, M|Tanimura, H|Tabor, E
PMID: 10427140
Journal: Life Sci. 2000 Sep 15;67(17):2117-24.
Title: Inhibition of P-glycoprotein expression and reversal of drug resistance of human hepatoma HepG2 cells by multidrug resistance gene (mdr1) antisense RNA.
Author: Chan, J Y|Chu, A C|Fung, K P
PMID: 11057761
Journal: Mol Carcinog. 2000 Oct;29(2):103-11.
Title: Elevated expression of hepatic proliferative markers during early hepatocarcinogenesis in hepatitis-B virus transgenic mice lacking mdr1a-encoded P-glycoprotein.
Author: Bao, J J|Lee, B P|Stephens, L C|Sahin, A A|Van, N T|Johnston, D A|Ou, C N|Kuo, M T
PMID: 11074607
Journal: World J Gastroenterol. 2002 Aug;8(4):644-9.
Title: Subcellular daunorubicin distribution and its relation to multidrug resistance phenotype in drug-resistant cell line SMMC-7721/R.
Author: Yang, Jia-Yin|Luo, Hua-You|Lin, Qi-Yuan|Liu, Zi-Ming|Yan, Lu-Nan|Lin, Ping|Zhang, Jie|Lei, Shong
PMID: 12174371
Journal: Hepatology. 2002 Oct;36(4 Pt 1):874-84.
Title: Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MDR1 ribozymes.
Author: Huesker, Matthes|Folmer, Yvonne|Schneider, Michaela|Fulda, Christine|Blum, Hubert E|Hafkemeyer, Peter
PMID: 12297834
Journal: Mol Med. 2002 Jun;8(6):318-25.
Title: Gene expression of ABC proteins in hepatocellular carcinoma, perineoplastic tissue, and liver diseases.
Author: Bonin, Serena|Pascolo, Lorella|Croce, Lory S|Stanta, Giorgio|Tiribelli, Claudio
PMID: 12428063
Journal: Mol Pharmacol. 2003 Mar;63(3):742-50.
Title: Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors.
Author: Briz, Oscar|Macias, Rocio I R|Vallejo, Marta|Silva, Augusto|Serrano, Maria Angeles|Marin, Jose J G
PMID: 12606785
Journal: Zhonghua Zhong Liu Za Zhi. 2003 Jan;25(1):17-20.
Title: [Selective myelo-protection by MDR1 and MnSOD genes regulated by a specific promoter].
Author: Liang, Li-bo|Ma, Ye-wei|Zhou, Xiao-shan|Yang, Jun|Li, Yan-chun|Wang, Zheng|Zhou, Lan-ping|Zhang, Yang-pei|Zhao, Qing-zheng
PMID: 12678980
Journal: Carcinogenesis. 2003 Dec;24(12):1977-84.
Title: Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats.
Author: Kankesan, Janarthanan|Yusuf, Aroon|Laconi, Ezio|Vanama, Ramesh|Bradley, Grace|Thiessen, Jake J|Ling, Victor|Rao, Prema M|Rajalakshmi, Srinivasan|Sarma, Dittakavi S R
PMID: 12970066
Journal: Zhonghua Wai Ke Za Zhi. 2003 Sep;41(9):676-8.
Title: [To set up a mdrl multidrug resistant model of orthotopic transplantation of liver carcinoma in nude mice].
Author: Han, Yu|Chen, Xiao-ping
PMID: 14680568
Journal: Ai Zheng. 2004 Apr;23(4):401-5.
Title: [MDR-reversing effect of two components of catechin on human hepatocellular carcinoma BEL-7404/Adr in vitro].
Author: Liang, Gang|Zhang, Su|Huang, Zhi-Ming|Tang, An-Zhou
PMID: 15087027
Journal: Chemotherapy. 2004 Jun;50(3):119-26.
Title: Hypoxia-inducible factor 1alpha- mediated resistance to phenolic anticancer.
Author: Hyun, Ju-Yeon|Chun, Yang-Sook|Kim, Tae-You|Kim, Hye-Lim|Kim, Myung-Suk|Park, Jong-Wan
PMID: 15272226
Journal: World J Gastroenterol. 2004 Nov 1;10(21):3107-11.
Title: Nude mice model of human hepatocellular carcinoma via orthotopic implantation of histologically intact tissue.
Author: Gao, Yong-Shun|Chen, Xiao-Ping|Li, Kai-Yan|Wu, Zai-De
PMID: 15457553
Journal: Int J Oncol. 2004 Nov;25(5):1357-64.
Title: Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes.
Author: Hu, Ying|Pang, Elizabeth|Lai, Paul B-S|Squire, Jeremy A|MacGregor, Pascale F|Beheshti, Ben|Albert, Monique|Leung, Thomas W-T|Wong, Nathalie
PMID: 15492826
Journal: Zhongguo Zhong Yao Za Zhi. 2004 Oct;29(10):970-3.
Title: [Study on ligustrazine in reversing multidrug resistance of HepG2/ADM cell in vitro].
Author: Mei, Ying|Shi, Yu-jun|Zuo, Guo-qing|Gong, Jian-ping|Liu, Chang-an|Li, Xu-hong|Ren, Meng-jun
PMID: 15631086
Journal: Lab Invest. 2005 May;85(5):664-74.
Title: Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells.
Author: Pang, Elizabeth|Hu, Ying|Chan, Kathy Y-Y|Lai, Paul B-S|Squire, Jeremy A|Macgregor, Pascale F|Beheshti, Ben|Albert, Monique|Leung, Thomas W-T|Wong, Nathalie
PMID: 15765123
Journal: J Hepatol. 2005 May;42(5):736-43.
Title: Increase of doxorubicin sensitivity by doxorubicin-loading into nanoparticles for hepatocellular carcinoma cells in vitro and in vivo.
Author: Barraud, Luc|Merle, Philippe|Soma, Emilienne|Lefrancois, Lydie|Guerret, Sylviane|Chevallier, Michele|Dubernet, Catherine|Couvreur, Patrick|Trepo, Christian|Vitvitski, Ludmila
PMID: 15826724
Journal: Zhonghua Wai Ke Za Zhi. 2005 Mar 1;43(5):277-81.
Title: [Hypoxia-inducible factor-1 alpha dependent expression and significance of the related multidrug resistance genes induced by hypoxia in human hepatocarcinoma cell].
Author: Zhu, Hong|Chen, Xiao-ping|Luo, Shun-feng|Guan, Jian|Zhang, Wan-guang|Zhang, Bi-xiang|Wang, Hai-ping
PMID: 15842930
Journal: World J Gastroenterol. 2005 Jun 14;11(22):3339-45.
Title: CIK cells from patients with HCC possess strong cytotoxicity to multidrug-resistant cell line Bel-7402/R.
Author: Zhang, You-Shun|Yuan, Fang-Jun|Jia, Guo-Feng|Zhang, Ji-Fa|Hu, Li-Yi|Huang, Ling|Wang, Ju|Dai, Zong-Qing
PMID: 15948236
Journal: Zhonghua Wai Ke Za Zhi. 2005 Oct 1;43(19):1248-53.
Title: [Synergistic effect of bromocriptine combining tumor necrosis factor-alpha on reversing multidrug resistance in a nude mouse model of liver neoplasm].
Author: Ding, Lei|Chen, Xiao-ping|Zhang, Zhi-wei|Wang, Hai|Cao, Bin|Wang, Zhi-hui|Li, Chun-lei
PMID: 16271222
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2005 Nov;36(6):765-9.
Title: [Construction of recombinant adeno-associated virus vectors carrying double gene of antisense multidrug resistance-associated protein and antisense multidrug resistance].
Author: Zhang, Ming-Man|Li, De-Hua|Yan, Lu-Ian|Gou, Xing-Hua|Zhao, Yong-Heng|Su, Zhi|Huang, Ying-Chun|Han, Lei|Zhao, Lan-Ying|Hu, Hai-Yang
PMID: 16334547
Journal: J Exp Clin Cancer Res. 2005 Dec;24(4):565-74.
Title: Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells.
Author: Zhu, H|Chen, X P|Luo, S F|Guan, J|Zhang, W G|Zhang, B X
PMID: 16471319
Journal: Pharmacogenet Genomics. 2006 Jun;16(6):415-27.
Title: Increased CYP3A4 copy number in TONG/HCC cells but not in DNA from other humans.
Author: Lamba, Jatinder K|Chen, Xin|Lan, Lu-Bin|Kim, Jin Woo|Wei Wang, Xin|Relling, Mary V|Kazuto, Yasuda|Watkins, Paul B|Strom, Stephen|Sun, Daxi|Schuetz, John D|Schuetz, Erin G
PMID: 16708050
Journal: Zhonghua Gan Zang Bing Za Zhi. 2006 May;14(5):341-5.
Title: [Reversion of multidrug resistance of hepatocellular carcinoma by antisense oligonucleotides and ultrasonic microbubble intensifier transfection combined with ultrasound irradiation].
Author: Jiang, Ming-dong|Peng, Zhi-ping|Li, Shao-lin|Wang, Zhi-gang|Ran, Hai-tao|Huo, Sai-hu|Yin, Xiao-ling
PMID: 16732907
Journal: Hepatobiliary Pancreat Dis Int. 2006 Nov;5(4):552-9.
Title: Effects of multidrug resistance, antisense RNA on the chemosensitivity of hepatocellular carcinoma cells.
Author: Li, Bo|Ye, Tian|Zhao, Lei|Li, De-Hua|Gou, Xing-Hua|Zhao, Lan-Ying|Han, Lei|Chen, Lin|Yan, Lu-Nan|Gong, Jian-Ping
PMID: 17085341
Journal: Yao Xue Xue Bao. 2006 Dec;41(12):1146-51.
Title: [Chemosensitivity of mdr1 gene overexpressed multidrug resistant cancer cells to lidamycin].
Author: Shi, Yi-Kang|Wu, Shu-Ying|Huang, Yun-Hong|Zhen, Yong-Su
PMID: 17290610
Journal: Zhonghua Wai Ke Za Zhi. 2006 Dec 1;44(23):1644-7.
Title: [Study on sensitivity to chemotherapy by combination therapy with tumor necrosis factor-alpha and bromocriptine in the multidrug resistant subcell line of HepG2].
Author: Ding, Lei|Chen, Xiao-ping|Zhang, Zhi-wei|Jing, Kai|Cao, Bin|Zhu, Peng|Li, Jie|Zhang, De-yong
PMID: 17359700
Journal: Zhonghua Gan Zang Bing Za Zhi. 2007 Mar;15(3):199-203.
Title: [Reversal of adriamycin resistance of hepatocellular carcinoma by targeting it with recombined adenovirus carrying antisense multidrug resistance gene 1 RNA].
Author: Mei, Ying|Shi, Yu-jun|Ding, Xiong|Wu, Chuan-xin|Jian, Hua-gang|Gong, Jian-ping|Liu, Chang-an
PMID: 17407711
Journal: Mol Cancer. 2007 May 9;6:32.
Title: N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma.
Author: Kudo, Takeaki|Nakagawa, Hiroaki|Takahashi, Masato|Hamaguchi, Jun|Kamiyama, Naoya|Yokoo, Hideki|Nakanishi, Kazuaki|Nakagawa, Takahito|Kamiyama, Toshiya|Deguchi, Kisaburo|Nishimura, Shin-Ichiro|Todo, Satoru
PMID: 17488527
Journal: Cancer Res. 2007 May 15;67(10):4915-23.
Title: P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines.
Author: Fantappie, Ornella|Solazzo, Michela|Lasagna, Nadia|Platini, Francesca|Tessitore, Luciana|Mazzanti, Roberto
PMID: 17510421
Journal: Chin Med J (Engl). 2007 Apr 20;120(8):703-7.
Title: Establishment of hepatocellular carcinoma multidrug resistant monoclone cell line HepG2/mdr1.
Author: Chen, Yong-Bing|Yan, Mao-Lin|Gong, Jian-Ping|Xia, Ren-Pin|Liu, Li-Xin|Li, Ning|Lu, Shi-Chun|Zhang, Jing-Guang|Zeng, Dao-Bing|Xie, Jian-Guo|Yang, Jia-Yin|Yan, Lu-Nan
PMID: 17517188
Journal: Cancer Gene Ther. 2007 Nov;14(11):875-84.
Title: Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs.
Author: Folmer, Y|Schneider, M|Blum, H E|Hafkemeyer, P
PMID: 17704753
Journal: Zhonghua Wai Ke Za Zhi. 2007 Jul 1;45(13):917-20.
Title: [The role of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance of hepatocellular carcinoma].
Author: Zhu, Hong|Chen, Xiao-Ping|Luo, Shun-Feng|Guan, Jian|Zhang, Wan-Guang|Zhang, Bi-Xiang|Mao, Cai-Ping
PMID: 17953842
Journal: Int J Oncol. 2007 Dec;31(6):1465-72.
Title: The combination of glycyrrhizin and lamivudine can reverse the cisplatin resistance in hepatocellular carcinoma cells through inhibition of multidrug resistance-associated proteins.
Author: Wakamatsu, Takahiro|Nakahashi, Yoshitsugu|Hachimine, Daisaku|Seki, Toshihito|Okazaki, Kazuichi
PMID: 17982673
Journal: Cancer Lett. 2008 Sep 28;269(1):101-10.
Title: Reversal effect of tyroservatide (YSV) tripeptide on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FU.
Author: Shi, Lin-Xi|Ma, Rui|Lu, Rong|Xu, Qiong|Zhu, Zhi-Feng|Wang, Li|Zhou, Chun-Lei|Li, Xiao-Lei|Zhang, Hua-Li|Yao, Zhi
PMID: 18538471
Journal: Cancer Lett. 2008 Dec 8;272(1):102-9.
Title: Cantharidin reverses multidrug resistance of human hepatoma HepG2/ADM cells via down-regulation of P-glycoprotein expression.
Author: Zheng, Li Hua|Bao, Yong Li|Wu, Yin|Yu, Chun Lei|Meng, Xiangying|Li, Yu Xin
PMID: 18703276
Journal: Bioconjug Chem. 2008 Oct;19(10):2008-22.
Title: 64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics.
Author: Yang, Chang-Tong|Kim, Young-Seung|Wang, Jianjun|Wang, Lijun|Shi, Jiyun|Li, Zi-Bo|Chen, Xiaoyuan|Fan, Ming|Li, Jian-Jian|Liu, Shuang
PMID: 18763821
Journal: Ai Zheng. 2008 Oct;27(10):1056-64.
Title: [Impact of epigallocatechin gallate on gene expression profiles of human hepatocellular carcinoma cell lines BEL7404/ADM and BEL7402/5-FU].
Author: Tang, Hai-Hua|Zhou, Ming|Liang, Gang
PMID: 18851785
Journal: Liver Int. 2008 Dec;28(10):1370-80.
Title: Expression of multidrug resistance-associated protein 1 in hepatocellular carcinoma is associated with a more aggressive tumour phenotype and may reflect a progenitor cell origin.
Author: Vander Borght, Sara|Komuta, Mina|Libbrecht, Louis|Katoonizadeh, Aezam|Aerts, Raymond|Dymarkowski, Steven|Verslype, Chris|Nevens, Frederik|Roskams, Tania
PMID: 19055643
Journal: Cancer Invest. 2008 Dec;26(10):977-83.
Title: Expression of CD147 mediates tumor cells invasion and multidrug resistance in hepatocellular carcinoma.
Author: Jia, Li|Xu, Henggui|Zhao, Yongfu|Jiang, Lili|Yu, Jingda|Zhang, Jianing
PMID: 19093255
Journal: Clin Chim Acta. 2009 May;403(1-2):142-4.
Title: The effects of splicing variant of PXR PAR-2 on CYP3A4 and MDR1 mRNA expressions.
Author: Liu, Yan|Ji, Wei|Yin, You|Fan, Lan|Zhang, Jian|Yun, Huang|Wang, Nianci|Li, Qing|Wei, Zhang|Ouyang, Dongshen|Zhou, Hong-Hao
PMID: 19232333
Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009 Apr;25(4):344-7.
Title: [Reversion of drug-resistant hepatocellular carcinoma cell line BEL-7402/FU by sorafenib].
Author: Wei, Li|Su, Ning|Zheng, Da-yong|Cao, Meng-ran|Li, Ai-min|Yan, Xiao|Lu, Cheng-wei|Luo, Rong-cheng
PMID: 19351508
Journal: Biochem Pharmacol. 2009 Jul 1;78(1):21-32.
Title: Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line.
Author: Mazzanti, Roberto|Platini, Francesca|Bottini, Consuelo|Fantappie, Ornella|Solazzo, Michela|Tessitore, Luciana
PMID: 19447220
Journal: Cancer Chemother Pharmacol. 2010 Apr;65(5):903-11.
Title: Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line.
Author: Roy, Karnati R|Reddy, Gorla V|Maitreyi, Leela|Agarwal, Smita|Achari, Chandrani|Vali, Shireen|Reddanna, Pallu
PMID: 19685055
Journal: Liver Int. 2010 Apr;30(4):585-92.
Title: Synergism of hydroxyapatite nanoparticles and recombinant mutant human tumour necrosis factor-alpha in chemotherapy of multidrug-resistant hepatocellular carcinoma.
Author: Li, Gaopeng|Dong, Shengli|Qu, Junyuan|Sun, Zhengang|Huang, Zhiyong|Ye, Lu|Liang, Huifang|Ai, Xi|Zhang, Wanguang|Chen, Xiaoping
PMID: 19780956
Journal: Chin J Cancer. 2010 Feb;29(2):167-71.
Title: Establishment of a cisplatin-induced multidrug resistance cell line SK-Hep1/DDP.
Author: Zhou, Yuan|Ling, Xian-Long
PMID: 20109345
Journal: World J Gastroenterol. 2010 May 14;16(18):2291-7.
Title: Establishment of a human hepatoma multidrug resistant cell line in vitro.
Author: Zhou, Yuan|Ling, Xian-Long|Li, Shi-Wei|Li, Xin-Qiang|Yan, Bin
PMID: 20458768
Journal: Int J Biol Sci. 2010 Dec 6;6(7):773-83.
Title: Modulation of mitochondrial permeability transition pore affects multidrug resistance in human hepatocellular carcinoma cells.
Author: Ling, Xianlong|Zhou, Yuan|Li, Shi-Wei|Yan, Bin|Wen, Lei
PMID: 21152118
Journal: Apoptosis. 2011 May;16(5):524-35.
Title: P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells.
Author: Tsang, Tsun Yee|Tang, Wan Yee|Chan, Judy Yuet Wa|Co, Ngai Na|Au Yeung, Chi Lam|Yau, Pak Lun|Kong, Siu Kai|Fung, Kwok Pui|Kwok, Tim Tak
PMID: 21336967
Journal: PLoS One. 2011;6(11):e27362.
Title: The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma.
Author: Geng, Wei|Ng, Kevin T P|Sun, Chris K W|Yau, Wing Lung|Liu, Xiao Bing|Cheng, Qiao|Poon, Ronnie T P|Lo, Chung Mau|Man, Kwan|Fan, Sheung Tat
PMID: 22096562
Journal: Zhonghua Gan Zang Bing Za Zhi. 2011 Oct;19(10):755-8.
Title: [Expressions and significance of COX-2 and P-gp in human hepatocellular carcinoma tissues].
Author: Li, Bo|Liu, Yong|Su, Song|Zhang, Meng-yu|Yuan, Qing|Chen, Chuan|Xia, Xian-ming|Liu, Chang-an|Gong, Jian-ping
PMID: 22409848
Journal: Xenobiotica. 2012 Jun;42(6):562-70.
Title: Reversal of P-glycoprotein-mediated multidrug resistance in human hepatoma cells by hedyotiscone A, a compound isolated from Hedyotis corymbosa.
Author: Yue, Grace Gar-Lee|Kin-Ming Lee, Julia|Cheng, Ling|Chung-Lap Chan, Ben|Jiang, Lei|Fung, Kwok-Pui|Leung, Ping-Chung|Bik-San Lau, Clara
PMID: 22352391
Journal: Chin Med J (Engl). 2012 Mar;125(6):1095-103.
Title: Effect of environmental factors on chemoresistance of HepG2 cells by regulating hypoxia-inducible factor-1alpha.
Author: Zhu, Hong|Luo, Shun-feng|Wang, Ji|Li, Xin|Wang, Hui|Pu, Wang-yang|Zhang, Hong|Zhuang, Zhi-xiang
PMID: 22613537
Journal: BMC Complement Altern Med. 2012 Jul 11;12:94.
Title: Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro.
Author: Tian, Qing E|De Li, Huan|Yan, Miao|Cai, Hua-Lin|Tan, Qin-You|Zhang, Wen-Yuan
PMID: 22784390
Journal: Bioorg Med Chem Lett. 2012 Nov 1;22(21):6577-9.
Title: Downregulation of mdr1 and abcg2 genes is a mechanism of inhibition of efflux pumps mediated by polymeric amphiphiles.
Author: Cuestas, Maria L|Castillo, Amalia I|Sosnik, Alejandro|Mathet, Veronica L
PMID: 23031592
Journal: Ann Hepatol. 2012 Nov-Dec;11(6):899-906.
Title: Evaluation of the C3435T polymorphism in the MDR1 gene in patients with hepatocellular carcinoma.
Author: Baldissera, Vanessa Dido|de Mattos, Angelo Alves|Coral, Gabriela Perdomo|de Araujo, Fernanda Branco|Marroni, Claudio Augusto|de Mello Brandao, Ajacio Bandeira|Ott Fontes, Paulo Roberto|Schmidt Cerski, Carlos Thadeu|Hartmann, Antonio Atalibio|Kretzmann Fil
PMID: 23109454
Journal: Asian Pac J Cancer Prev. 2012;13(11):5451-4.
Title: Association of MDR1 gene polymorphisms with susceptibility to hepatocellular carcinoma in the Chinese population.
Author: Ren, Yong-Qiang|Han, Ju-Qiang|Cao, Jian-Biao|Li, Shao-Xiang|Fan, Gong-Ren
PMID: 23317199
Journal: Anat Rec (Hoboken). 2013 Jan;296(1):56-63.
Title: TFPI-2 downregulates multidrug resistance protein in 5-FU-resistant human hepatocellular carcinoma BEL-7402/5-FU cells.
Author: Lu, Fei|Hou, Yong-Qiang|Song, Ying|Yuan, Zheng-Jiang
PMID: 23125179
Journal: Biomarkers. 2013 May;18(3):236-41.
Title: Association analysis between MDR1 gene polymorphisms and risk of hepatocellular carcinoma in Chinese population.
Author: Yang, Daokun|Zhou, Fujun|Wang, Xinwei|Gao, Haili|Li, Guangyan|Xue, Minghui
PMID: 23488625
Journal: Life Sci. 2013 May 20;92(17-19):896-902.
Title: Silencing the EZH2 gene by RNA interference reverses the drug resistance of human hepatic multidrug-resistant cancer cells to 5-Fu.
Author: Zhang, Yi|Liu, Guangpu|Lin, Changwei|Liao, Guoqing|Tang, Bo
PMID: 23562851
Journal: Virol J. 2013 May 29;10:168.
Title: Interferon-alpha sensitizes HBx-expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx-mediated NF-kappaB activation.
Author: Liu, Yanning|Lou, Guohua|Wu, Wei|Shi, Yu|Zheng, Min|Chen, Zhi
PMID: 23718853
Journal: Cell Signal. 2013 Dec;25(12):2693-701.
Title: MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/beta-catenin pathway in hepatocellular carcinoma cells.
Author: Chen, Zhaolin|Ma, Taotao|Huang, Cheng|Zhang, Lei|Lv, Xiongwen|Xu, Tao|Hu, Tingting|Li, Jun
PMID: 24018051
Journal: Mol Med Rep. 2013 Dec;8(6):1883-7.
Title: Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and Pglycoprotein expression.
Author: Sun, Li|Chen, Weigang|Qu, Lili|Wu, Jie|Si, Jin
PMID: 24145579
Journal: Pathol Oncol Res. 2014 Jul;20(3):541-8.
Title: Reversing multidrug-resistant by RNA interference through silencing MDR1 gene in human hepatocellular carcinoma cells subline Bel-7402/ADM.
Author: Sheng, Long|Xiong, Maoming|Li, Cong|Meng, Xiangling
PMID: 24327315
Journal: Int J Oncol. 2014 Jun;44(6):2034-40.
Title: Knockdown of NANOG enhances chemosensitivity of liver cancer cells to doxorubicin by reducing MDR1 expression.
Author: Zhou, Jia-Jia|Deng, Xiao-Geng|He, Xiao-Yu|Zhou, Yu|Yu, Min|Gao, Wen-Chao|Zeng, Bing|Zhou, Quan-Bo|Li, Zhi-Hua|Chen, Ru-Fu
PMID: 24647772
Journal: Mol Pharm. 2014 Jun 2;11(6):1856-68.
Title: The expression of genes involved in hepatocellular carcinoma chemoresistance is affected by mitochondrial genome depletion.
Author: Gonzalez-Sanchez, Ester|Marin, Jose J G|Perez, Maria J
PMID: 24824514
Journal: Cell Biosci. 2014 Aug 26;4:49.
Title: Peptidylarginine deiminase IV promotes the development of chemoresistance through inducing autophagy in hepatocellular carcinoma.
Author: Fan, Tingting|Zhang, Changsong|Zong, Ming|Zhao, Qiudong|Yang, Xue|Hao, Chong|Zhang, Hui|Yu, Shanshan|Guo, Jinhu|Gong, Ruhan|Fan, Shasha|Wei, Lixin|Fan, Lieying
PMID: 25922661
Journal: Eur J Med Chem. 2015 Jan 7;89:851-62.
Title: Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents.
Author: Bandyopadhyay, Debasish|Sanchez, Jorge L|Guerrero, Adrian M|Chang, Fang-Mei|Granados, Jose C|Short, John D|Banik, Bimal K
PMID: 25462285
Journal: Oncotarget. 2015 Jan 20;6(2):1049-63.
Title: ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA.
Author: Ma, Hongxin|Yue, Xuetian|Gao, Lifen|Liang, Xiaohong|Yan, Wenjiang|Zhang, Zhenyu|Shan, Haixia|Zhang, Hualin|Spear, Brett T|Ma, Chunhong
PMID: 25473899
Journal: Tumour Biol. 2015 May;36(5):3995-4003.
Title: Silencing clusterin gene transcription on effects of multidrug resistance reversing of human hepatoma HepG2/ADM cells.
Author: Zheng, Wenjie|Sai, Wenli|Yao, Min|Gu, Hongbin|Yao, Yao|Qian, Qi|Yao, Dengfu
PMID: 25600802
Journal: J Cell Mol Med. 2015 Jun;19(6):1410-7.
Title: Mitochondria of a human multidrug-resistant hepatocellular carcinoma cell line constitutively express inducible nitric oxide synthase in the inner membrane.
Author: Fantappie, Ornella|Sassoli, Chiara|Tani, Alessia|Nosi, Daniele|Marchetti, Serena|Formigli, Lucia|Mazzanti, Roberto
PMID: 25691007
Journal: Mol Cancer Ther. 2015 Aug;14(8):1805-15.
Title: Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells.
Author: Chen, Bryan Wei|Chen, Wei|Liang, Hui|Liu, Hao|Liang, Chao|Zhi, Xiao|Hu, Li-Qiang|Yu, Xia-Zhen|Wei, Tao|Ma, Tao|Xue, Fei|Zheng, Lei|Zhao, Bin|Feng, Xin-Hua|Bai, Xue-Li|Liang, Ting-Bo
PMID: 26026051
Journal: Toxicol Sci. 2015 Oct;147(2):412-24.
Title: Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.
Author: Sison-Young, Rowena L C|Mitsa, Dimitra|Jenkins, Rosalind E|Mottram, David|Alexandre, Eliane|Richert, Lysiane|Aerts, Helene|Weaver, Richard J|Jones, Robert P|Johann, Esther|Hewitt, Philip G|Ingelman-Sundberg, Magnus|Goldring, Christopher E P|Kitteringham,
PMID: 26160117
Journal: Biochem Pharmacol. 2015 Dec 15;98(4):703-17.
Title: Protein kinase C-dependent regulation of human hepatic drug transporter expression.
Author: Mayati, Abdullah|Le Vee, Marc|Moreau, Amelie|Jouan, Elodie|Bucher, Simon|Stieger, Bruno|Denizot, Claire|Parmentier, Yannick|Fardel, Olivier
PMID: 26462574
Journal: Int J Clin Exp Pathol. 2015 Sep 1;8(9):11934-44. eCollection 2015.
Title: Annonaceous acetogenins reverses drug resistance of human hepatocellular carcinoma BEL-7402/5-FU and HepG2/ADM cell lines.
Author: Qian, Jun-Qiang|Sun, Pei|Pan, Zhan-Yu|Fang, Zhi-Zhong
PMID: 26617951
Journal: Zhonghua Gan Zang Bing Za Zhi. 2015 Nov;23(11):844-8.
Title: [Down-regulated clusterin expression enhances sensitivity of hepatoma cells to anti-cancer drugs].
Author: Zheng, Wen-Jie|Sai, Wen-Li|Yao, Min|Cai, Yin|Pan, Liu-Hong|Gu, Juan-Juan|Wu, Wei|Yao, Deng-Fu
PMID: 26743245
Journal: Oncotarget. 2016 Feb 9;7(6):7207-15.
Title: MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma.
Author: Tomonari, Tetsu|Takeishi, Shunsaku|Taniguchi, Tatsuya|Tanaka, Takahiro|Tanaka, Hironori|Fujimoto, Shota|Kimura, Tetsuo|Okamoto, Koichi|Miyamoto, Hiroshi|Muguruma, Naoki|Takayama, Tetsuji
PMID: 26769852
Journal: Eur Rev Med Pharmacol Sci. 2016;20(6):1098-108.
Title: Inhibition of the JNK signaling pathway increases sensitivity of hepatocellular carcinoma cells to cisplatin by down-regulating expression of P-glycoprotein.
Author: Liu, X-Y|Liu, S-P|Jiang, J|Zhang, X|Zhang, T
PMID: 27049263
Journal: Anticancer Res. 2016 Jun;36(6):2675-82.
Title: siRNA Targeting of MDR1 Reverses Multidrug Resistance in a Nude Mouse Model of Doxorubicin-resistant Human Hepatocellular Carcinoma.
Author: Yang, Haitao|Ding, Rui|Tong, Zhong|Huang, Jun|Shen, Lei|Sun, Y U|Liao, Jing|Yang, Zhijian|Hoffman, Robert M|Wang, Chenghong|Meng, Xiangling
PMID: 27272776
Journal: Zhonghua Gan Zang Bing Za Zhi. 2016 Jul 20;24(7):493-499.
Title: [Role of inhibition of nuclear factor-kappa B gene transcription by specific miRNA in reversing multi-drug resistance of liver cancer].
Author: Wang, L|Cai, Y|Shi, Y|Yao, M|Pan, L H|Gu, J J|Yang, X L|Wu, W|Yao, D F
PMID: 27784426
Journal: EXCLI J. 2016 Nov 11;15:687-698.
Title: Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis.
Author: Bogaerts, Eliene|Paridaens, Annelies|Verhelst, Xavier|Carmeliet, Peter|Geerts, Anja|Van Vlierberghe, Hans|Devisscher, Lindsey
PMID: 28337100
Journal: Oncotarget. 2017 Jan 24;8(4):6718-6729.
Title: Positive feedback loop of IL-1beta/Akt/RARalpha/Akt signaling mediates oncogenic property of RARalpha in gastric carcinoma.
Author: Ren, Hong-Yue|Liu, Fan|Huang, Gui-Li|Liu, Yu|Shen, Jin-Xing|Zhou, Pan|Liu, Wen-Ming|Shen, Dong-Yan
PMID: 28035062
Journal: J Pharm Pharmacol. 2017 Jun;69(6):743-752.
Title: Astragaloside II sensitizes human hepatocellular carcinoma cells to 5-fluorouracil via suppression of autophagy.
Author: Wang, Meng|Huang, Can|Su, Yong|Yang, Cui|Xia, Quan|Xu, Du-Juan
PMID: 28266023
Journal: Cell Cycle. 2017 Apr 3;16(7):685-692.
Title: Oncogenic retinoic acid receptor gamma knockdown reverses multi-drug resistance of human colorectal cancer via Wnt/beta-catenin pathway.
Author: Huang, Gui-Li|Song, Wei|Zhou, Pan|Fu, Qi-Rui|Lin, Chen-Lu|Chen, Qing-Xi|Shen, Dong-Yan
PMID: 28272990
Journal: Environ Pollut. 2017 Jun;225:610-619.
Title: Altered cellular metabolism of HepG2 cells caused by microcystin-LR.
Author: Ma, Junguo|Feng, Yiyi|Jiang, Siyu|Li, Xiaoyu
PMID: 28336091
Journal: Oncotarget. 2017 Apr 11;8(15):24728-24740.
Title: USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt.
Author: Zhang, Jing|Luo, Nan|Tian, Yu|Li, Jiazhi|Yang, Xiaozhou|Yin, Huimin|Xiao, Congshu|Sheng, Jie|Li, Yang|Tang, Bo|Li, Rongkuan
PMID: 28445968
Journal: Int J Oncol. 2018 Jan;52(1):189-200.
Title: Apoptosis in human liver carcinoma caused by gold nanoparticles in combination with carvedilol is mediated via modulation of MAPK/Akt/mTOR pathway and EGFR/FAAD proteins.
Author: De Araujo, Raimundo F Jr|Pessoa, Jonas B|Cruz, Luis J|Chan, Alan B|De Castro Miguel, Emilio|Cavalcante, Romulo S|Brito, Gerly Anne C|Silva, Heloiza Fernada O|Gasparotto, Luiz H S|Guedes, Paulo M M|Araujo, Aurigena A
PMID: 29115423
Journal: Curr Med Chem. 2018 Jan 4. pii: CMC-EPUB-87731.
Title: ABC transporters: Regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma.
Author: Ceballos, Maria Paula|Rigalli, Juan Pablo|Cere, Lucila Ines|Semeniuk, Mariana|Catania, Viviana Alicia|Ruiz, Maria Laura
PMID: 29303075
Journal: Front Pharmacol. 2018 Mar 6;9:194.
Title: SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression.
Author: Xia, Yang Q|Hua, Ren J|Juan, Chen|Zhong, Zhou H|Tao, Cheng S|Fang, Ren|Lin, He|Rui, Gong|Yong, Chen
PMID: 29563873
Journal: J Cell Mol Med. 2018 Jun;22(6):3238-3245.
Title: LncRNA NR2F1-AS1 regulates hepatocellular carcinoma oxaliplatin resistance by targeting ABCC1 via miR-363.
Author: Huang, Hai|Chen, Jie|Ding, Cheng-Ming|Jin, Xin|Jia, Ze-Ming|Peng, Jian
PMID: 29602203
Journal: Biochem Biophys Res Commun. 2018 Jul 12;502(2):194-201.
Title: Effect of long non-coding RNA H19 on oxidative stress and chemotherapy resistance of CD133+ cancer stem cells via the MAPK/ERK signaling pathway in hepatocellular carcinoma.
Author: Ding, Kai|Liao, Yannian|Gong, Dinghao|Zhao, Xin|Ji, Wu
PMID: 29800569
Journal: Biochem Biophys Res Commun. 2018 Sep 18;503(4):2400-2406.
Title: Long non-coding RNA KCNQ1OT1 modulates oxaliplatin resistance in hepatocellular carcinoma through miR-7-5p/ ABCC1 axis.
Author: Hu, Huiqin|Yang, Li|Li, Lijun|Zeng, Changchun
PMID: 29966655