Primary Site >> Liver Cancer
Gene >> TBC1D9
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas. PMID: 2122232 |
Ref: Human hepatocellular carcinoma cell lines exhibit multidrug resistance unrelated to MRD1 gene expression. PMID: 1676033 |
Ref: Activation of multidrug resistance (P-glycoprotein) mdr3/mdr1a gene during the development of hepatocellular carcinoma in hepatitis B virus transgenic mice. PMID: 1356418 |
Ref: P-glycoprotein expression in hepatocellular carcinoma. PMID: 8095077 Ref: MDR1 (multidrug resistance) gene expression in human primary liver cancer and cirrhosis. PMID: 8409332 Ref: Effects of hyperthermia on multidrug-resistant human hepatocellular-carcinoma. PMID: 21573662 |
Ref: Constitutive expression of functional P-glycoprotein in rat hepatoma cells. PMID: 7905826 Ref: MDR1 gene expression: its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines. PMID: 7908989 Ref: Modulation of tumor cell response to chemotherapy by the organ environment. PMID: 7923551 |
Ref: Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms. PMID: 7473127 Ref: Cell-specific effects of RAS oncogene and protein kinase C agonist TPA on P-glycoprotein function. PMID: 7628641 Ref: Characterisation of high-level cisplatin-resistant cell lines established from a human hepatoma cell line and human KB adenocarcinoma cells: cross-resistance and protein changes. PMID: 7710928 |
Ref: Overexpression of a p-glycoprotein in hepatocellular carcinomas from woodchuck hepatitis virus-infected woodchucks (Marmota monax). PMID: 8666315 Ref: Expression of the low-density lipoprotein receptor, HMG-CoA reductase, and multidrug resistance (Mdr1) genes in colorectal carcinomas. PMID: 8678896 Ref: Expression of P-glycoprotein in hepatocellular carcinoma: a potential marker of prognosis. PMID: 8763260 |
Ref: Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis. PMID: 9288777 Ref: Effect of a xanthine analog on human hepatocellular carcinoma cells (Alexander) in culture and in xenografts in SCID mice. PMID: 9362362 |
Ref: Transactivation of the human MDR1 gene by hepatitis B virus X gene product. PMID: 9875632 |
Ref: Overexpression of multidrug resistance genes MDR1 and cMOAT in human hepatocellular carcinoma and hepatoblastoma cell lines. PMID: 10427140 |
Ref: Inhibition of P-glycoprotein expression and reversal of drug resistance of human hepatoma HepG2 cells by multidrug resistance gene (mdr1) antisense RNA. PMID: 11057761 Ref: Elevated expression of hepatic proliferative markers during early hepatocarcinogenesis in hepatitis-B virus transgenic mice lacking mdr1a-encoded P-glycoprotein. PMID: 11074607 |
Ref: Subcellular daunorubicin distribution and its relation to multidrug resistance phenotype in drug-resistant cell line SMMC-7721/R. PMID: 12174371 Ref: Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MDR1 ribozymes. PMID: 12297834 Ref: Gene expression of ABC proteins in hepatocellular carcinoma, perineoplastic tissue, and liver diseases. PMID: 12428063 |
Ref: Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors. PMID: 12606785 Ref: [Selective myelo-protection by MDR1 and MnSOD genes regulated by a specific promoter]. PMID: 12678980 Ref: Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats. PMID: 12970066 Ref: [To set up a mdrl multidrug resistant model of orthotopic transplantation of liver carcinoma in nude mice]. PMID: 14680568 |
Ref: [MDR-reversing effect of two components of catechin on human hepatocellular carcinoma BEL-7404/Adr in vitro]. PMID: 15087027 Ref: Hypoxia-inducible factor 1alpha- mediated resistance to phenolic anticancer. PMID: 15272226 Ref: Nude mice model of human hepatocellular carcinoma via orthotopic implantation of histologically intact tissue. PMID: 15457553 Ref: Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes. PMID: 15492826 Ref: [Study on ligustrazine in reversing multidrug resistance of HepG2/ADM cell in vitro]. PMID: 15631086 |
Ref: Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells. PMID: 15765123 Ref: Increase of doxorubicin sensitivity by doxorubicin-loading into nanoparticles for hepatocellular carcinoma cells in vitro and in vivo. PMID: 15826724 Ref: [Hypoxia-inducible factor-1 alpha dependent expression and significance of the related multidrug resistance genes induced by hypoxia in human hepatocarcinoma cell]. PMID: 15842930 Ref: CIK cells from patients with HCC possess strong cytotoxicity to multidrug-resistant cell line Bel-7402/R. PMID: 15948236 Ref: [Synergistic effect of bromocriptine combining tumor necrosis factor-alpha on reversing multidrug resistance in a nude mouse model of liver neoplasm]. PMID: 16271222 Ref: [Construction of recombinant adeno-associated virus vectors carrying double gene of antisense multidrug resistance-associated protein and antisense multidrug resistance]. PMID: 16334547 Ref: Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells. PMID: 16471319 |
Ref: Increased CYP3A4 copy number in TONG/HCC cells but not in DNA from other humans. PMID: 16708050 Ref: [Reversion of multidrug resistance of hepatocellular carcinoma by antisense oligonucleotides and ultrasonic microbubble intensifier transfection combined with ultrasound irradiation]. PMID: 16732907 Ref: Effects of multidrug resistance, antisense RNA on the chemosensitivity of hepatocellular carcinoma cells. PMID: 17085341 Ref: [Chemosensitivity of mdr1 gene overexpressed multidrug resistant cancer cells to lidamycin]. PMID: 17290610 Ref: [Study on sensitivity to chemotherapy by combination therapy with tumor necrosis factor-alpha and bromocriptine in the multidrug resistant subcell line of HepG2]. PMID: 17359700 |
Ref: [Reversal of adriamycin resistance of hepatocellular carcinoma by targeting it with recombined adenovirus carrying antisense multidrug resistance gene 1 RNA]. PMID: 17407711 Ref: N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma. PMID: 17488527 Ref: P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines. PMID: 17510421 Ref: Establishment of hepatocellular carcinoma multidrug resistant monoclone cell line HepG2/mdr1. PMID: 17517188 Ref: Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs. PMID: 17704753 Ref: [The role of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance of hepatocellular carcinoma]. PMID: 17953842 Ref: The combination of glycyrrhizin and lamivudine can reverse the cisplatin resistance in hepatocellular carcinoma cells through inhibition of multidrug resistance-associated proteins. PMID: 17982673 |
Ref: Reversal effect of tyroservatide (YSV) tripeptide on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FU. PMID: 18538471 Ref: Cantharidin reverses multidrug resistance of human hepatoma HepG2/ADM cells via down-regulation of P-glycoprotein expression. PMID: 18703276 Ref: 64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics. PMID: 18763821 Ref: [Impact of epigallocatechin gallate on gene expression profiles of human hepatocellular carcinoma cell lines BEL7404/ADM and BEL7402/5-FU]. PMID: 18851785 Ref: Expression of multidrug resistance-associated protein 1 in hepatocellular carcinoma is associated with a more aggressive tumour phenotype and may reflect a progenitor cell origin. PMID: 19055643 Ref: Expression of CD147 mediates tumor cells invasion and multidrug resistance in hepatocellular carcinoma. PMID: 19093255 |
Ref: The effects of splicing variant of PXR PAR-2 on CYP3A4 and MDR1 mRNA expressions. PMID: 19232333 Ref: [Reversion of drug-resistant hepatocellular carcinoma cell line BEL-7402/FU by sorafenib]. PMID: 19351508 Ref: Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line. PMID: 19447220 |
Ref: Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line. PMID: 19685055 Ref: Synergism of hydroxyapatite nanoparticles and recombinant mutant human tumour necrosis factor-alpha in chemotherapy of multidrug-resistant hepatocellular carcinoma. PMID: 19780956 Ref: Establishment of a cisplatin-induced multidrug resistance cell line SK-Hep1/DDP. PMID: 20109345 Ref: Establishment of a human hepatoma multidrug resistant cell line in vitro. PMID: 20458768 Ref: Modulation of mitochondrial permeability transition pore affects multidrug resistance in human hepatocellular carcinoma cells. PMID: 21152118 |
Ref: P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. PMID: 21336967 Ref: The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma. PMID: 22096562 Ref: [Expressions and significance of COX-2 and P-gp in human hepatocellular carcinoma tissues]. PMID: 22409848 |
Ref: Reversal of P-glycoprotein-mediated multidrug resistance in human hepatoma cells by hedyotiscone A, a compound isolated from Hedyotis corymbosa. PMID: 22352391 Ref: Effect of environmental factors on chemoresistance of HepG2 cells by regulating hypoxia-inducible factor-1alpha. PMID: 22613537 Ref: Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro. PMID: 22784390 Ref: Downregulation of mdr1 and abcg2 genes is a mechanism of inhibition of efflux pumps mediated by polymeric amphiphiles. PMID: 23031592 Ref: Evaluation of the C3435T polymorphism in the MDR1 gene in patients with hepatocellular carcinoma. PMID: 23109454 Ref: Association of MDR1 gene polymorphisms with susceptibility to hepatocellular carcinoma in the Chinese population. PMID: 23317199 |
Ref: TFPI-2 downregulates multidrug resistance protein in 5-FU-resistant human hepatocellular carcinoma BEL-7402/5-FU cells. PMID: 23125179 Ref: Association analysis between MDR1 gene polymorphisms and risk of hepatocellular carcinoma in Chinese population. PMID: 23488625 Ref: Silencing the EZH2 gene by RNA interference reverses the drug resistance of human hepatic multidrug-resistant cancer cells to 5-Fu. PMID: 23562851 Ref: Interferon-alpha sensitizes HBx-expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx-mediated NF-kappaB activation. PMID: 23718853 Ref: MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/beta-catenin pathway in hepatocellular carcinoma cells. PMID: 24018051 Ref: Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and Pglycoprotein expression. PMID: 24145579 |
Ref: Reversing multidrug-resistant by RNA interference through silencing MDR1 gene in human hepatocellular carcinoma cells subline Bel-7402/ADM. PMID: 24327315 Ref: Knockdown of NANOG enhances chemosensitivity of liver cancer cells to doxorubicin by reducing MDR1 expression. PMID: 24647772 Ref: The expression of genes involved in hepatocellular carcinoma chemoresistance is affected by mitochondrial genome depletion. PMID: 24824514 Ref: Peptidylarginine deiminase IV promotes the development of chemoresistance through inducing autophagy in hepatocellular carcinoma. PMID: 25922661 |
Ref: Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents. PMID: 25462285 Ref: ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA. PMID: 25473899 Ref: Silencing clusterin gene transcription on effects of multidrug resistance reversing of human hepatoma HepG2/ADM cells. PMID: 25600802 Ref: Mitochondria of a human multidrug-resistant hepatocellular carcinoma cell line constitutively express inducible nitric oxide synthase in the inner membrane. PMID: 25691007 Ref: Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells. PMID: 26026051 Ref: Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication. PMID: 26160117 Ref: Protein kinase C-dependent regulation of human hepatic drug transporter expression. PMID: 26462574 Ref: Annonaceous acetogenins reverses drug resistance of human hepatocellular carcinoma BEL-7402/5-FU and HepG2/ADM cell lines. PMID: 26617951 Ref: [Down-regulated clusterin expression enhances sensitivity of hepatoma cells to anti-cancer drugs]. PMID: 26743245 |
Ref: MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma. PMID: 26769852 Ref: Inhibition of the JNK signaling pathway increases sensitivity of hepatocellular carcinoma cells to cisplatin by down-regulating expression of P-glycoprotein. PMID: 27049263 Ref: siRNA Targeting of MDR1 Reverses Multidrug Resistance in a Nude Mouse Model of Doxorubicin-resistant Human Hepatocellular Carcinoma. PMID: 27272776 Ref: [Role of inhibition of nuclear factor-kappa B gene transcription by specific miRNA in reversing multi-drug resistance of liver cancer]. PMID: 27784426 Ref: Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis. PMID: 28337100 |
Ref: Positive feedback loop of IL-1beta/Akt/RARalpha/Akt signaling mediates oncogenic property of RARalpha in gastric carcinoma. PMID: 28035062 Ref: Astragaloside II sensitizes human hepatocellular carcinoma cells to 5-fluorouracil via suppression of autophagy. PMID: 28266023 Ref: Oncogenic retinoic acid receptor gamma knockdown reverses multi-drug resistance of human colorectal cancer via Wnt/beta-catenin pathway. PMID: 28272990 Ref: Altered cellular metabolism of HepG2 cells caused by microcystin-LR. PMID: 28336091 Ref: USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt. PMID: 28445968 |
Ref: Apoptosis in human liver carcinoma caused by gold nanoparticles in combination with carvedilol is mediated via modulation of MAPK/Akt/mTOR pathway and EGFR/FAAD proteins. PMID: 29115423 Ref: ABC transporters: Regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma. PMID: 29303075 Ref: SIRT6 Depletion Sensitizes Human Hepatoma Cells to Chemotherapeutics by Downregulating MDR1 Expression. PMID: 29563873 Ref: LncRNA NR2F1-AS1 regulates hepatocellular carcinoma oxaliplatin resistance by targeting ABCC1 via miR-363. PMID: 29602203 Ref: Effect of long non-coding RNA H19 on oxidative stress and chemotherapy resistance of CD133+ cancer stem cells via the MAPK/ERK signaling pathway in hepatocellular carcinoma. PMID: 29800569 Ref: Long non-coding RNA KCNQ1OT1 modulates oxaliplatin resistance in hepatocellular carcinoma through miR-7-5p/ ABCC1 axis. PMID: 29966655 |