Primary Site >> Colorectal Cancer

Gene >> TACR1

Journal: Regul Pept. 2000 Mar 17;88(1-3):1-13.
Title: Pronounced substance P innervation in irradiation-induced enteropathy--a study on human colon.
Author: Forsgren, S|Hockerfelt, U|Norrgard, O|Henriksson, R|Franzen, L
PMID: 10706946
Journal: Invest New Drugs. 2010 Apr;28(2):187-93.
Title: The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug.
Author: Munoz, Miguel|Rosso, Marisa
PMID: 19148578
Journal: Peptides. 2010 Sep;31(9):1643-8.
Title: The broad-spectrum antitumor action of cyclosporin A is due to its tachykinin receptor antagonist pharmacological profile.
Author: Munoz, Miguel|Rosso, Marisa|Gonzalez, Ana|Saenz, Javier|Covenas, Rafael
PMID: 20542069
Journal: Anticancer Res. 2010 Sep;30(9):3345-53.
Title: Effect of a neurokinin-1 receptor antagonist in a rat model of colitis-associated colon cancer.
Author: Pagan, Beatriz|Isidro, Angel A|Coppola, Domenico|Chen, Zhengming|Ren, Yuan|Wu, Jie|Appleyard, Caroline B
PMID: 20944107
Journal: Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17420-5.
Title: Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer.
Author: Gillespie, Earl|Leeman, Susan E|Watts, Luisa A|Coukos, Jennifer A|O'Brien, Michael J|Cerda, Sandra R|Farraye, Francis A|Stucchi, Arthur F|Becker, James M
PMID: 21969570
Journal: Int J Colorectal Dis. 2012 Nov;27(11):1429-36.
Title: Association of genetic variants in tachykinins pathway genes with colorectal cancer risk.
Author: Yu, Yunxian|Pan, Yifeng|Jin, Mingjuan|Zhang, Mingwu|Zhang, Shanchun|Li, Qilong|Jiang, Xia|Liu, Hui|Guo, Jing|Liu, He|Chen, Kun
PMID: 22733436
Journal: World J Gastroenterol. 2015 Feb 14;21(6):1749-58.
Title: Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia.
Author: Isidro, Raymond A|Cruz, Myrella L|Isidro, Angel A|Baez, Axel|Arroyo, Axel|Gonzalez-Marques, William A|Gonzalez-Keelan, Carmen|Torres, Esther A|Appleyard, Caroline B
PMID: 25684939
Journal: Int J Oncol. 2015 Jul;47(1):151-60.
Title: Targeting the neurokinin-1 receptor inhibits growth of human colon cancer cells.
Author: Garnier, Agnes|Vykoukal, Jody|Hubertus, Jochen|Alt, Eckhard|von Schweinitz, Dietrich|Kappler, Roland|Berger, Michael|Ilmer, Matthias
PMID: 25998227
Journal: Oncol Lett. 2015 May;9(5):2003-2006.
Title: Neurokinin-2 receptor polymorphism predicts lymph node metastasis in colorectal cancer patients.
Author: Fang, Weijia|Fu, Caiyun|Chen, Xiaogang|Mou, Xiaozhou|Liu, Fanlong|Qian, Jiong|Zhao, Peng|Zheng, Yulong|Zheng, Y I|Deng, Jing|Ye, Pingjiang|Wang, Yifei|Zheng, Shusen
PMID: 26137002
Journal: Onco Targets Ther. 2016 Jun 16;9:3595-602.
Title: High expression of substance P and its receptor neurokinin-1 receptor in colorectal cancer is associated with tumor progression and prognosis.
Author: Chen, Xiao-Yi|Ru, Guo-Qing|Ma, Ying-Yu|Xie, Jun|Chen, Wan-Yuan|Wang, Hui-Ju|Wang, Shi-Bing|Li, Li|Jin, Ke-Tao|He, Xiang-Lei|Mou, Xiao-Zhou
PMID: 27366097
Journal: Drug Des Devel Ther. 2017 Sep 5;11:2621-2629.
Title: Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations.
Author: Rapoport, Bernardo Leon|Aapro, Matti|Chasen, Martin R|Jordan, Karin|Navari, Rudolph M|Schnadig, Ian|Schwartzberg, Lee
PMID: 28919712
Journal: Oncol Lett. 2017 Sep;14(3):3729-3733.
Title: Difference in expression of two neurokinin-1 receptors in adenoma and carcinoma from patients that underwent radical surgery for colorectal carcinoma.
Author: Gao, Xia|Wang, Zhenjun
PMID: 28927139