Primary Site >> Colorectal Cancer
Gene >> TACR1
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Ref: Pronounced substance P innervation in irradiation-induced enteropathy--a study on human colon. PMID: 10706946 |
Ref: The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug. PMID: 19148578 Ref: The broad-spectrum antitumor action of cyclosporin A is due to its tachykinin receptor antagonist pharmacological profile. PMID: 20542069 Ref: Effect of a neurokinin-1 receptor antagonist in a rat model of colitis-associated colon cancer. PMID: 20944107 |
Ref: Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer. PMID: 21969570 |
Ref: Association of genetic variants in tachykinins pathway genes with colorectal cancer risk. PMID: 22733436 |
Ref: Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia. PMID: 25684939 Ref: Targeting the neurokinin-1 receptor inhibits growth of human colon cancer cells. PMID: 25998227 Ref: Neurokinin-2 receptor polymorphism predicts lymph node metastasis in colorectal cancer patients. PMID: 26137002 |
Ref: High expression of substance P and its receptor neurokinin-1 receptor in colorectal cancer is associated with tumor progression and prognosis. PMID: 27366097 |
Ref: Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations. PMID: 28919712 Ref: Difference in expression of two neurokinin-1 receptors in adenoma and carcinoma from patients that underwent radical surgery for colorectal carcinoma. PMID: 28927139 |