Primary Site >> Colorectal Cancer

Gene >> SUZ12

Journal: Genes Dev. 2004 Jul 1;18(13):1592-605.
Title: Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.
Author: Kirmizis, Antonis|Bartley, Stephanie M|Kuzmichev, Andrei|Margueron, Raphael|Reinberg, Danny|Green, Roland|Farnham, Peggy J
PMID: 15231737
Journal: Pathology. 2007 Feb;39(1):46-54.
Title: Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium.
Author: Lax, Sigurd F
PMID: 17365822
Journal: Cancer Res. 2011 Oct 15;71(20):6320-6.
Title: Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.
Author: Kogo, Ryunosuke|Shimamura, Teppei|Mimori, Koshi|Kawahara, Kohichi|Imoto, Seiya|Sudo, Tomoya|Tanaka, Fumiaki|Shibata, Kohei|Suzuki, Akira|Komune, Shizuo|Miyano, Satoru|Mori, Masaki
PMID: 21862635
Journal: J Cell Physiol. 2013 Apr;228(4):764-72.
Title: Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
Author: Benoit, Yannick D|Laursen, Kristian B|Witherspoon, Mavee S|Lipkin, Steven M|Gudas, Lorraine J
PMID: 23001792
Journal: Exp Cell Res. 2013 Jun 10;319(10):1463-70.
Title: Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.
Author: Benoit, Yannick D|Witherspoon, Mavee S|Laursen, Kristian B|Guezguez, Amel|Beausejour, Marco|Beaulieu, Jean-Francois|Lipkin, Steven M|Gudas, Lorraine J
PMID: 23588203
Journal: PLoS One. 2014 Sep 22;9(9):e108265.
Title: Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer.
Author: Benard, Anne|Goossens-Beumer, Ines J|van Hoesel, Anneke Q|Horati, Hamed|Putter, Hein|Zeestraten, Eliane C M|van de Velde, Cornelis J H|Kuppen, Peter J K
PMID: 25243792
Journal: Exp Cell Res. 2015 Nov 1;338(2):214-21.
Title: Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells.
Author: Wang, Haibo|Ge, Shengfang|Qian, Guanxiang|Li, Wei|Cui, Jiuwei|Wang, Guanjun|Hoffman, Andrew R|Hu, Ji-Fan
PMID: 26407907
Journal: Carcinogenesis. 2015 Mar;36(3):355-67.
Title: Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer.
Author: Toden, Shusuke|Okugawa, Yoshinaga|Jascur, Thomas|Wodarz, Dominik|Komarova, Natalia L|Buhrmann, Constanze|Shakibaei, Mehdi|Boland, C Richard|Goel, Ajay
PMID: 25653233
Journal: Int J Oncol. 2015 Apr;46(4):1788-800.
Title: Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer.
Author: Liao, Mei-Ying|Kuo, Mark Yen-Ping|Lu, Tung-Ying|Wang, Yi-Ping|Wu, Han-Chung
PMID: 25652097
Journal: J Cancer Res Clin Oncol. 2015 Apr;141(4):661-9.
Title: Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer.
Author: Liu, Yan-Long|Gao, Xu|Jiang, Yang|Zhang, Gan|Sun, Zi-Cheng|Cui, Bin-Bin|Yang, Yan-Mei
PMID: 25326896
Journal: Cancer Res. 2016 Jan 15;76(2):275-82.
Title: PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer.
Author: Nagarsheth, Nisha|Peng, Dongjun|Kryczek, Ilona|Wu, Ke|Li, Wei|Zhao, Ende|Zhao, Lili|Wei, Shuang|Frankel, Timothy|Vatan, Linda|Szeliga, Wojciech|Dou, Yali|Owens, Scott|Marquez, Victor|Tao, Kaixiong|Huang, Emina|Wang, Guobin|Zou, Weiping
PMID: 26567139
Journal: Oncotarget. 2016 Mar 29;7(13):16158-71.
Title: Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer.
Author: Toden, Shusuke|Tran, Hanh-My|Tovar-Camargo, Oscar A|Okugawa, Yoshinaga|Goel, Ajay
PMID: 26930714
Journal: Oncoimmunology. 2015 Sep 2;5(8):e1082704.
Title: Th22 cells control colon tumorigenesis through STAT3 and Polycomb Repression complex 2 signaling.
Author: Sun, Danfeng|Lin, Yanwei|Hong, Jie|Chen, Haoyan|Nagarsheth, Nisha|Peng, Dongjun|Wei, Shuang|Huang, Emina|Fang, Jingyuan|Kryczek, Ilona|Zou, Weiping
PMID: 27622053
Journal: Oncotarget. 2017 Apr 25;8(17):29138-29150.
Title: Brain-derived neurotrophic factor involved epigenetic repression of UGT2B7 in colorectal carcinoma: A mechanism to alter morphine glucuronidation in tumor.
Author: Yang, Zi-Zhao|Li, Li|Xu, Ming-Cheng|Ju, Hai-Xing|Hao, Miao|Gu, Jing-Kai|Jim Wang, Zai-Jie|Jiang, Hui-Di|Yu, Lu-Shan|Zeng, Su
PMID: 28418861
Journal: Cancer Res. 2017 Jun 15;77(12):3194-3206.
Title: tRF/miR-1280 Suppresses Stem Cell-like Cells and Metastasis in Colorectal Cancer.
Author: Huang, Bingqing|Yang, Huipeng|Cheng, Xixi|Wang, Dan|Fu, Shuyu|Shen, Wencui|Zhang, Qi|Zhang, Lijuan|Xue, Zhenyi|Li, Yan|Da, Yurong|Yang, Qing|Li, Zesong|Liu, Li|Qiao, Liang|Kong, Ying|Yao, Zhi|Zhao, Peng|Li, Min|Zhang, Rongxin
PMID: 28446464
Journal: Cancer Res. 2017 Oct 15;77(20):5464-5478.
Title: STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway.
Author: Jin, Lin|Vu, Trung|Yuan, Guandou|Datta, Pran K
PMID: 28827371
Journal: Genes Cancer. 2017 Jul;8(7-8):673-681.
Title: Deregulated expression of microRNA-200b/c and SUZ12, a Polycomb repressive complex 2 subunit, in chemoresistant colorectal cancer cells.
Author: San, KayKay|Horita, Megan|Ganapathy, Aravinda|Chinnadurai, G|Ezekiel, Uthayashanker R
PMID: 28966728
Journal: Int J Cancer. 2018 Jan 15;142(2):308-321.
Title: Tumor-suppressive miR-145 co-repressed by TCF4-beta-catenin and PRC2 complexes forms double-negative regulation loops with its negative regulators in colorectal cancer.
Author: Wang, Wei|Xiao, Xin|Chen, Xu|Huo, Yi|Xi, Wen-Jin|Lin, Zhi-Feng|Zhang, Dan|Li, Yu-Fang|Yang, Fan|Wen, Wei-Hong|Yang, An-Gang|Wang, Tao
PMID: 28921929