Primary Site >> Esophagus Cancer

Gene >> STK11

Journal: Pharmacogenomics. 2010 Aug;11(8):1105-13.
Title: CUL2 and STK11 as novel response-predictive genes for neoadjuvant radiochemotherapy in esophageal cancer.
Author: Metzger, Ralf|Heukamp, Lukas|Drebber, Uta|Bollschweiler, Elfriede|Zander, Thomas|Hoelscher, Arnulf H|Warnecke-Eberz, Ute
PMID: 20712528
Journal: Oncogene. 2012 Jan 26;31(4):469-79.
Title: Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion.
Author: Gu, Y|Lin, S|Li, J-L|Nakagawa, H|Chen, Z|Jin, B|Tian, L|Ucar, D A|Shen, H|Lu, J|Hochwald, S N|Kaye, F J|Wu, L
PMID: 21706049
Journal: Tumour Biol. 2014 Feb;35(2):995-1002.
Title: The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma.
Author: Liu, Kai|Luo, Yue|Tian, Hui|Yu, Kai-Zhong|He, Jin-Xian|Shen, Wei-Yu
PMID: 24022664
Journal: Mol Med Rep. 2014 Jun;9(6):2400-4.
Title: Downregulation of LKB1 suppresses Stat3 activity to promote the proliferation of esophageal carcinoma cells.
Author: Wang, Yu-Qi|Dai, Wei-Min|Chu, Xiang-Yang|Yang, Bo|Zhao, Ming|Sun, Yu'e
PMID: 24676538
Journal: Oncol Rep. 2016 Jun;35(6):3559-65.
Title: Radiation-induced autophagy promotes esophageal squamous cell carcinoma cell survival via the LKB1 pathway.
Author: Lu, Chi|Xie, Conghua
PMID: 27109915
Journal: Mol Med Rep. 2017 Aug;16(2):2205-2210.
Title: LKB1 promotes radioresistance in esophageal cancer cells exposed to radiation, by suppression of apoptosis and activation of autophagy via the AMPK pathway.
Author: He, Qing|Li, Jing|Dong, Feng|Cai, Chuanshu|Zou, Xi
PMID: 28656285
Journal: J Thorac Cardiovasc Surg. 2018 Apr;155(4):1891-1899.
Title: LKB1 inactivation occurs in a subset of esophageal adenocarcinomas and is sufficient to drive tumor cell proliferation.
Author: Whitsett, Timothy G|Mittal, Sumeet K|Eschbacher, Jennifer M|Carson, Vashti M|Smith, Michael A|Bremner, Ross M|Inge, Landon J
PMID: 29370903