Primary Site >> Esophagus Cancer
Gene >> STK11
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Ref: CUL2 and STK11 as novel response-predictive genes for neoadjuvant radiochemotherapy in esophageal cancer. PMID: 20712528 |
Ref: Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion. PMID: 21706049 |
Ref: The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma. PMID: 24022664 Ref: Downregulation of LKB1 suppresses Stat3 activity to promote the proliferation of esophageal carcinoma cells. PMID: 24676538 |
Ref: Radiation-induced autophagy promotes esophageal squamous cell carcinoma cell survival via the LKB1 pathway. PMID: 27109915 |
Ref: LKB1 promotes radioresistance in esophageal cancer cells exposed to radiation, by suppression of apoptosis and activation of autophagy via the AMPK pathway. PMID: 28656285 |
Ref: LKB1 inactivation occurs in a subset of esophageal adenocarcinomas and is sufficient to drive tumor cell proliferation. PMID: 29370903 |