Literatures

Primary Site >> Colorectal Cancer

Gene >> STK11

1.
Journal:	Curr Opin Genet Dev. 1998 Jun;8(3):298-303.
Title:	The genetics of hereditary common cancers.
Author:	de la Chapelle, A\|Peltomaki, P
PMID:	9690990

2.
Journal:	Cancer Res. 1998 May 15;58(10):2087-90.
Title:	Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors.
Author:	Avizienyte, E\|Roth, S\|Loukola, A\|Hemminki, A\|Lothe, R A\|Stenwig, A E\|Fossa, S D\|Salovaara, R\|Aaltonen, L A
PMID:	9605748

3.
Journal:	Cancer Res. 1998 Dec 1;58(23):5267-70.
Title:	Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.
Author:	Gruber, S B\|Entius, M M\|Petersen, G M\|Laken, S J\|Longo, P A\|Boyer, R\|Levin, A M\|Mujumdar, U J\|Trent, J M\|Kinzler, K W\|Vogelstein, B\|Hamilton, S R\|Polymeropoulos, M H\|Offerhaus, G J\|Giardiello, F M
PMID:	9850045

4.
Journal:	Cancer Res. 1998 Nov 1;58(21):4799-801.
Title:	STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer.
Author:	Resta, N\|Simone, C\|Mareni, C\|Montera, M\|Gentile, M\|Susca, F\|Gristina, R\|Pozzi, S\|Bertario, L\|Bufo, P\|Carlomagno, N\|Ingrosso, M\|Rossini, F P\|Tenconi, R\|Guanti, G
PMID:	9809980

5.
Journal:	Cancer Res. 1998 Sep 1;58(17):3787-90.
Title:	Frequent somatic mutations in serine/threonine kinase 11/Peutz-Jeghers syndrome gene in left-sided colon cancer.
Author:	Dong, S M\|Kim, K M\|Kim, S Y\|Shin, M S\|Na, E Y\|Lee, S H\|Park, W S\|Yoo, N J\|Jang, J J\|Yoon, C Y\|Kim, J W\|Kim, S Y\|Yang, Y M\|Kim, S H\|Kim, C S\|Lee, J Y
PMID:	9731485

6.
Journal:	Am J Pathol. 1998 Aug;153(2):363-6.
Title:	Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes.
Author:	Wang, Z J\|Taylor, F\|Churchman, M\|Norbury, G\|Tomlinson, I
PMID:	9708796

7.
Journal:	Am J Pathol. 1999 Mar;154(3):677-81.
Title:	LKB1 somatic mutations in sporadic tumors.
Author:	Avizienyte, E\|Loukola, A\|Roth, S\|Hemminki, A\|Tarkkanen, M\|Salovaara, R\|Arola, J\|Butzow, R\|Husgafvel-Pursiainen, K\|Kokkola, A\|Jarvinen, H\|Aaltonen, L A
PMID:	10079245

8.
Journal:	J Invest Dermatol. 1999 Apr;112(4):509-11.
Title:	Somatic mutations in the Peutz-Jeghers (LKB1/STKII) gene in sporadic malignant melanomas.
Author:	Rowan, A\|Bataille, V\|MacKie, R\|Healy, E\|Bicknell, D\|Bodmer, W\|Tomlinson, I
PMID:	10201537

9.
Journal:	J Pathol. 1999 May;188(1):9-13.
Title:	Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence.
Author:	Wang, Z J\|Ellis, I\|Zauber, P\|Iwama, T\|Marchese, C\|Talbot, I\|Xue, W H\|Yan, Z Y\|Tomlinson, I
PMID:	10398133

10.
Journal:	Jpn J Cancer Res. 1999 Jun;90(6):633-7.
Title:	Frameshift mutation of the STK11 gene in a sporadic gastrointestinal cancer with microsatellite instability.
Author:	Nakagawa, H\|Koyama, K\|Nakamori, S\|Kameyama, M\|Imaoka, S\|Monden, M\|Nakamura, Y
PMID:	10429655

11.
Journal:	Oncogene. 2000 Jan 6;19(1):164-8.
Title:	Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome.
Author:	Esteller, M\|Avizienyte, E\|Corn, P G\|Lothe, R A\|Baylin, S B\|Aaltonen, L A\|Herman, J G
PMID:	10644993

12.
Journal:	Cancer Res. 2000 Feb 1;60(3):546-8.
Title:	No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas.
Author:	Launonen, V\|Avizienyte, E\|Loukola, A\|Laiho, P\|Salovaara, R\|Jarvinen, H\|Mecklin, J P\|Oku, A\|Shimane, M\|Kim, H C\|Kim, J C\|Nezu, J\|Aaltonen, L A
PMID:	10676634

13.
Journal:	Gut. 2000 Aug;47(2):272-6.
Title:	5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer.
Author:	Trojan, J\|Brieger, A\|Raedle, J\|Esteller, M\|Zeuzem, S
PMID:	10896921

14.
Journal:	J Clin Pathol. 2001 Feb;54(2):126-31.
Title:	Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome.
Author:	Entius, M M\|Keller, J J\|Westerman, A M\|van Rees, B P\|van Velthuysen, M L\|de Goeij, A F\|Wilson, J H\|Giardiello, F M\|Offerhaus, G J
PMID:	11215281

15.
Journal:	Br J Cancer. 2001 May 18;84(10):1314-6.
Title:	CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers.
Author:	Woodford-Richens, K L\|Halford, S\|Rowan, A\|Bevan, S\|Aaltonen, L A\|Wasan, H\|Bicknell, D\|Bodmer, W F\|Houlston, R S\|Tomlinson, I P
PMID:	11355940

16.
Journal:	Hum Mol Genet. 2001 Dec 15;10(26):3001-7.
Title:	DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.
Author:	Esteller, M\|Fraga, M F\|Guo, M\|Garcia-Foncillas, J\|Hedenfalk, I\|Godwin, A K\|Trojan, J\|Vaurs-Barriere, C\|Bignon, Y J\|Ramus, S\|Benitez, J\|Caldes, T\|Akiyama, Y\|Yuasa, Y\|Launonen, V\|Canal, M J\|Rodriguez, R\|Capella, G\|Peinado, M A\|Borg, A\|Aaltonen, L A\|Ponder,
PMID:	11751682

17.
Journal:	J Gastroenterol. 2002;37(5):376-80.
Title:	Duodenal cancer in a patient with Peutz-Jeghers syndrome: molecular analysis.
Author:	Nakamura, Toshio\|Suzuki, Shohachi\|Yokoi, Yoshihiro\|Kashiwabara, Hidefumi\|Maruyama, Keiji\|Baba, Satoshi\|Nakagawa, Hidewaki\|Nakamura, Satoshi
PMID:	12051537

18.
Journal:	Am J Med Genet A. 2003 Nov 1;122A(4):303-14.
Title:	Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
Author:	Cohen, M Michael Jr
PMID:	14518068

19.
Journal:	Hum Mutat. 2005 Oct;26(4):291-7.
Title:	Mutations in the human LKB1/STK11 gene.
Author:	Launonen, Virpi
PMID:	16110486

20.
Journal:	Korean J Gastroenterol. 2005 Feb;45(2):78-87.
Title:	[Hereditary colorectal cancer].
Author:	Park, Jae-Gahb\|Kim, Il-Jin
PMID:	15725711

21.
Journal:	Mod Pathol. 2005 Feb;18(2):170-8.
Title:	Progressive methylation during the serrated neoplasia pathway of the colorectum.
Author:	Dong, Seung M\|Lee, Eui J\|Jeon, Eun S\|Park, Cheol K\|Kim, Kyoung-Mee
PMID:	15389252

22.
Journal:	Magy Onkol. 2006;50(4):349-59. Epub 2007 Jan 10.
Title:	[Developments in cancer management by innovative genomics. 2006 report of the National Cancer Consortium].
Author:	Timar, Jozsef\|Kasler, Miklos\|Katai, Jozsef\|Soos, Miklos\|Mathiasz, Dora\|Romany, Anna\|Patthy, Laszlo\|Kovacs, Gabor\|Jozsa, Adrienn\|Szilak, Laszlo\|Forrai, Tamas
PMID:	17216011

23.
Journal:	Keio J Med. 2007 Mar;56(1):14-20.
Title:	Genetic testing in colorectal cancer: who, when, how and why.
Author:	Davidson, Nicholas O
PMID:	17392593

24.
Journal:	Cancer Res. 2007 Jun 15;67(12):5622-7.
Title:	LKB1 catalytically deficient mutants enhance cyclin D1 expression.
Author:	Scott, Kristine D\|Nath-Sain, Suchita\|Agnew, Meghan D\|Marignani, Paola A
PMID:	17575127

25.
Journal:	Br J Cancer. 2007 Nov 5;97(9):1305-9.
Title:	National study of colorectal cancer genetics.
Author:	Penegar, S\|Wood, W\|Lubbe, S\|Chandler, I\|Broderick, P\|Papaemmanuil, E\|Sellick, G\|Gray, R\|Peto, J\|Houlston, R
PMID:	17895893

26.
Journal:	Cancer Biol Ther. 2007 Oct;6(10):1627-31. Epub 2007 Jul 24.
Title:	Novel splice isoforms of STRADalpha differentially affect LKB1 activity, complex assembly and subcellular localization.
Author:	Marignani, P A\|Scott, K D\|Bagnulo, R\|Cannone, D\|Ferrari, E\|Stella, A\|Guanti, G\|Simone, C\|Resta, N
PMID:	17921699

27.
Journal:	Mol Cancer Ther. 2008 Jun;7(6):1337-46.
Title:	In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Author:	Ikediobi, Ogechi N\|Reimers, Mark\|Durinck, Steffen\|Blower, Paul E\|Futreal, Andrew P\|Stratton, Michael R\|Weinstein, John N
PMID:	18524847

28.
Journal:	J Gastrointest Surg. 2008 Oct;12(10):1745-53.
Title:	Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.
Author:	Dhir, Mashaal\|Montgomery, Elizabeth A\|Glockner, Sabine C\|Schuebel, Kornel E\|Hooker, Craig M\|Herman, James G\|Baylin, Stephen B\|Gearhart, Susan L\|Ahuja, Nita
PMID:	18716850

29.
Journal:	Cancer Res. 2008 Sep 15;68(18):7270-7.
Title:	LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins.
Author:	Zhong, Diansheng\|Liu, Xiuju\|Khuri, Fadlo R\|Sun, Shi-Yong\|Vertino, Paula M\|Zhou, Wei
PMID:	18794113

30.
Journal:	Cancer Prev Res (Phila). 2009 Nov;2(11):922-30.
Title:	Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiology.
Author:	Slattery, Martha L\|Fitzpatrick, F A
PMID:	19892662

31.
Journal:	J Biol Chem. 2010 Jun 11;285(24):18283-90.
Title:	LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain.
Author:	Deguchi, Atsuko\|Miyoshi, Hiroyuki\|Kojima, Yasushi\|Okawa, Katsuya\|Aoki, Masahiro\|Taketo, Makoto M
PMID:	20400510

32.
Journal:	Carcinogenesis. 2010 Sep;31(9):1604-11.
Title:	Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Author:	Slattery, Martha L\|Herrick, Jennifer S\|Lundgreen, Abbie\|Fitzpatrick, Francis A\|Curtin, Karen\|Wolff, Roger K
PMID:	20622004

33.
Journal:	Fam Cancer. 2011 Jun;10(2):323-30.
Title:	German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.
Author:	Schneider, Ralph\|Slater, Emily P\|Sina, Mercede\|Habbe, Nils\|Fendrich, Volker\|Matthai, Elvira\|Langer, Peter\|Bartsch, Detlef K
PMID:	21207249

34.
Journal:	BMC Med Genet. 2011 Dec 14;12:161.
Title:	A novel mutation in STK11 gene is associated with Peutz-Jeghers syndrome in Chinese patients.
Author:	Wang, Zhiqing\|Chen, Yulan\|Wu, Baoping\|Zheng, Haoxuan\|He, Jiman\|Jiang, Bo
PMID:	22168747

35.
Journal:	Gastroenterol Hepatol. 2012 Jun-Jul;35(6):395-9.
Title:	[Coexistence of Peutz-Jeghers' syndrome and Lynch's syndrome in the same patient].
Author:	Martinez Amate, Eva\|Carreno Gonzalez, Rocio\|Jorge Cerrudo, Jaime\|Esteban Carretero, Juan
PMID:	22516349

36.
Journal:	Oncol Rep. 2012 Sep;28(3):855-61.
Title:	Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy.
Author:	Saigusa, Susumu\|Tanaka, Koji\|Toiyama, Yuji\|Matsushita, Kohei\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Hiro, Junichiro\|Inoue, Yasuhiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22711167

37.
Journal:	BMC Evol Biol. 2012 Jul 12;12:114.
Title:	Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions.
Author:	Morgan, Claire C\|Shakya, Kabita\|Webb, Andrew\|Walsh, Thomas A\|Lynch, Mark\|Loscher, Christine E\|Ruskin, Heather J\|O'Connell, Mary J
PMID:	22788692

38.
Journal:	Asian Pac J Cancer Prev. 2013;14(6):3631-4.
Title:	MicroRNA-451 inhibits growth of human colorectal carcinoma cells via downregulation of Pi3k/Akt pathway.
Author:	Li, Hong-Yan\|Zhang, Yan\|Cai, Jian-Hui\|Bian, Hong-Lei
PMID:	23886157

39.
Journal:	Endocr Relat Cancer. 2013 Oct 24;20(6):849-59.
Title:	Adiponectin and metformin additively attenuate IL1beta-induced malignant potential of colon cancer.
Author:	Moon, Hyun-Seuk\|Mantzoros, Christos S
PMID:	24157941

40.
Journal:	Asian Pac J Cancer Prev. 2013;14(10):5609-14.
Title:	Genes and SNPs associated with non-hereditary and hereditary colorectal cancer.
Author:	Nassiri, Mohammadreza\|Kooshyar, Mohammad Mahdi\|Roudbar, Zahra\|Mahdavi, Morteza\|Doosti, Mohammad
PMID:	24289550

41.
Journal:	Gut. 2013 Apr;62(4):561-70.
Title:	Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice.
Author:	Moon, Hyun-Seuk\|Liu, Xiaowen\|Nagel, Jutta M\|Chamberland, John P\|Diakopoulos, Kalliope N\|Brinkoetter, Mary T\|Hatziapostolou, Maria\|Wu, Yan\|Robson, Simon C\|Iliopoulos, Dimitrios\|Mantzoros, Christos S
PMID:	22735569

42.
Journal:	J Nutr Biochem. 2013 Jun;24(6):1096-104.
Title:	20-O-beta-d-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginseng, inhibits colon cancer growth by targeting TRPC channel-mediated calcium influx.
Author:	Hwang, Jeong Ah\|Hwang, Mun Kyung\|Jang, Yongwoo\|Lee, Eun Jung\|Kim, Jong-Eun\|Oh, Mi Hyun\|Shin, Dong Joo\|Lim, Semi\|Ji, Geun og\|Oh, Uhtaek\|Bode, Ann M\|Dong, Zigang\|Lee, Ki Won\|Lee, Hyong Joo
PMID:	23318138

43.
Journal:	Scand J Gastroenterol. 2013 Jun;48(6):672-8.
Title:	Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients.
Author:	Tanskanen, Tomas\|Gylfe, Alexandra E\|Katainen, Riku\|Taipale, Minna\|Renkonen-Sinisalo, Laura\|Mecklin, Jukka-Pekka\|Jarvinen, Heikki\|Tuupanen, Sari\|Kilpivaara, Outi\|Vahteristo, Pia\|Aaltonen, Lauri A
PMID:	23544471

44.
Journal:	J Cancer Res Clin Oncol. 2013 Jan;139(1):131-8.
Title:	Significant correlation between LKB1 and LGR5 gene expression and the association with poor recurrence-free survival in rectal cancer after preoperative chemoradiotherapy.
Author:	Saigusa, Susumu\|Inoue, Yasuhiro\|Tanaka, Koji\|Toiyama, Yuji\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Okigami, Masato\|Hiro, Junichiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22986809

45.
Journal:	Ann Surg Oncol. 2014 Aug;21(8):2642-9.
Title:	The frequencies and clinical implications of mutations in 33 kinase-related genes in locally advanced rectal cancer: a pilot study.
Author:	Abdul-Jalil, Khairun I\|Sheehan, Katherine M\|Toomey, Sinead\|Schmid, Jasmin\|Prehn, Jochen\|O'Grady, Anthony\|Cummins, Robert\|O'Neill, Brian\|McNamara, Deborah A\|Deasy, Joseph\|Breathnach, Oscar\|Grogan, Liam\|Rogers, Ailin\|Doherty, Glen\|Winter, Des\|Ryan, John\|El-
PMID:	24700299

46.
Journal:	Ann Surg Oncol. 2014 Dec;21 Suppl 4:S634-9.
Title:	Genetic variations in STK11, PRKAA1, and TSC1 associated with prognosis for patients with colorectal cancer.
Author:	Lee, Soo Jung\|Kang, Byung Woog\|Chae, Yee Soo\|Kim, Hye Jin\|Park, Su Yeon\|Park, Jun Seok\|Choi, Gyu Seog\|Jeon, Hyo-Sung\|Lee, Won Kee\|Kim, Jong Gwang
PMID:	24770722

47.
Journal:	Ann Surg Oncol. 2014 Dec;21 Suppl 4:S703-10.
Title:	LKB1 loss at transcriptional level promotes tumor malignancy and poor patient outcomes in colorectal cancer.
Author:	He, Tsung-Ying\|Tsai, Lung-Hung\|Huang, Chi-Chou\|Chou, Ming-Chih\|Lee, Huei
PMID:	24879590

48.
Journal:	Br J Cancer. 2014 Jul 8;111(1):25-32.
Title:	Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab.
Author:	Zulato, E\|Bergamo, F\|De Paoli, A\|Griguolo, G\|Esposito, G\|De Salvo, G L\|Mescoli, C\|Rugge, M\|Nardin, M\|Di Grazia, L\|Lonardi, S\|Indraccolo, S\|Zagonel, V
PMID:	24892446

49.
Journal:	Int J Mol Epidemiol Genet. 2014 May 29;5(2):100-11. eCollection 2014.
Title:	Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.
Author:	Slattery, Martha L\|Lundgreen, Abbie\|Mullany, Lila E\|Penney, Rosalind B\|Wolff, Roger K
PMID:	24959314

50.
Journal:	Bull Cancer. 2014 Sep;101(9):813-22.
Title:	[Hereditary predisposition to cancers of the digestive tract, breast, gynecological and gonadal: focus on the Peutz-Jeghers].
Author:	Turpin, Anthony\|Cattan, Stephane\|Leclerc, Julie\|Wacrenier, Agnes\|Manouvrier-Hanu, Sylvie\|Buisine, Marie-Pierre\|Lejeune-Dumoulin, Sophie
PMID:	25036236

51.
Journal:	Mol Carcinog. 2015 Oct;54(10):1096-109.
Title:	Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
Author:	Li, Weidong\|Hua, Baojin\|Saud, Shakir M\|Lin, Hongsheng\|Hou, Wei\|Matter, Matthias S\|Jia, Libin\|Colburn, Nancy H\|Young, Matthew R
PMID:	24838344

52.
Journal:	Gynecol Oncol. 2015 Jan;136(1):3-7.
Title:	Society of Gynecologic Oncology statement on risk assessment for inherited gynecologic cancer predispositions.
Author:	Lancaster, Johnathan M\|Powell, C Bethan\|Chen, Lee-May\|Richardson, Debra L
PMID:	25238946

53.
Journal:	Gastroenterology. 2015 Mar;148(3):556-64.
Title:	Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author:	Grant, Robert C\|Selander, Iris\|Connor, Ashton A\|Selvarajah, Shamini\|Borgida, Ayelet\|Briollais, Laurent\|Petersen, Gloria M\|Lerner-Ellis, Jordan\|Holter, Spring\|Gallinger, Steven
PMID:	25479140

54.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):498-513. eCollection 2015.
Title:	ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma.
Author:	Tang, Yi\|Li, Ming\|Wang, Ya-Lan\|Threadgill, Michael D\|Xiao, Ming\|Mou, Chun-Feng\|Song, Guang-Lin\|Kuang, Jing\|Yang, Xi\|Yang, Li\|Gao, Xing-Jie\|Wang, Ya-Ping\|Meng, Yun-Peng
PMID:	25973293

55.
Journal:	Ann Clin Biochem. 2015 Nov;52(Pt 6):690-2.
Title:	The Mendelian colorectal cancer syndromes.
Author:	Tomlinson, Ian
PMID:	26169059

56.
Journal:	Mol Cancer. 2016 Oct 18;15(1):63.
Title:	Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author:	Kovaleva, Valentina\|Geissler, Anna-Lena\|Lutz, Lisa\|Fritsch, Ralph\|Makowiec, Frank\|Wiesemann, Sebastian\|Hopt, Ulrich T\|Passlick, Bernward\|Werner, Martin\|Lassmann, Silke
PMID:	27756406

57.
Journal:	Oncoimmunology. 2016 Mar 10;5(7):e1151591.
Title:	Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.
Author:	Vila-Leahey, Ava\|Oldford, Sharon A\|Marignani, Paola A\|Wang, Jun\|Haidl, Ian D\|Marshall, Jean S
PMID:	27622015

58.
Journal:	Med Oncol. 2016 Oct;33(10):106.
Title:	Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author:	Jauhri, Mayank\|Bhatnagar, Akanksha\|Gupta, Satish\|Shokeen, Yogender\|Minhas, Sachin\|Aggarwal, Shyam
PMID:	27568332

59.
Journal:	Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title:	Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author:	Pfarr, Nicole\|Penzel, Roland\|Klauschen, Frederick\|Heim, Daniel\|Brandt, Regine\|Kazdal, Daniel\|Jesinghaus, Moritz\|Herpel, Esther\|Schirmacher, Peter\|Warth, Arne\|Weichert, Wilko\|Endris, Volker\|Stenzinger, Albrecht
PMID:	27218826

60.
Journal:	Oncotarget. 2016 May 24;7(21):31336-49.
Title:	Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer.
Author:	Kan, Jung-Yu\|Yen, Meng-Chi\|Wang, Jaw-Yuan\|Wu, Deng-Chyang\|Chiu, Yen-Jung\|Ho, Ya-Wen\|Kuo, Po-Lin
PMID:	27150059

61.
Journal:	J Clin Pathol. 2016 Sep;69(9):767-71.
Title:	Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.
Author:	Malapelle, Umberto\|Pisapia, Pasquale\|Sgariglia, Roberta\|Vigliar, Elena\|Biglietto, Maria\|Carlomagno, Chiara\|Giuffre, Giuseppe\|Bellevicine, Claudio\|Troncone, Giancarlo
PMID:	26797410

62.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):27-38.
Title:	RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.
Author:	Fang, Bingliang
PMID:	26350096

63.
Journal:	Vascul Pharmacol. 2017 Mar;90:27-35.
Title:	Camptothecin promotes the production of nitric oxide that triggers subsequent S-nitrosoproteome-mediated signaling cascades in endothelial cells.
Author:	Huang, Bin\|Cheng, Jen-Kun\|Wu, Chien-Yi\|Chen, Ping-Ho\|Tu, Po-Shu\|Fu, Yaw-Syan\|Wu, Chien-Hsing
PMID:	26239883

64.
Journal:	Biochem Biophys Res Commun. 2017 Jan 22;482(4):1037-1041.
Title:	Par3L enhances colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway.
Author:	Li, Taiyuan\|Liu, Dongning\|Lei, Xiong\|Jiang, Qunguang
PMID:	27908725

65.
Journal:	Tumour Biol. 2017 Apr;39(4):1010428317698393.
Title:	High expression of partitioning defective 3-like protein is associated with malignancy in colorectal cancer.
Author:	Li, Taiyuan\|Liu, Xiaoyang\|Jiang, Qunguang\|Lei, Xiong\|Liu, Dongning
PMID:	28443499

66.
Journal:	Cold Spring Harb Mol Case Stud. 2017 May;3(3):a001610.
Title:	Genetic and epigenetic profiling of a solitary Peutz-Jeghers colon polyp.
Author:	Linhart, Heinz\|Bormann, Felix\|Hutter, Barbara\|Brors, Benedikt\|Lyko, Frank
PMID:	28487883

67.
Journal:	Cell Death Dis. 2017 May 11;8(5):e2789.
Title:	Halofuginone dually regulates autophagic flux through nutrient-sensing pathways in colorectal cancer.
Author:	Chen, Guo-Qing\|Gong, Rui-Hong\|Yang, Da-Jian\|Zhang, Ge\|Lu, Ai-Ping\|Yan, Siu-Cheong\|Lin, Shu-Hai\|Bian, Zhao-Xiang
PMID:	28492544

68.
Journal:	Am J Med Sci. 2017 Sep;354(3):246-251.
Title:	Metformin Has Positive Therapeutic Effects in Colon Cancer and Lung Cancer.
Author:	Henderson, DeAnna\|Frieson, Danielle\|Zuber, Jeffrey\|Solomon, Solomon S
PMID:	28918830

69.
Journal:	BMC Med Genet. 2017 Nov 15;18(1):130.
Title:	Sanger sequencing in exonic regions of STK11 gene uncovers a novel de-novo germline mutation (c.962_963delCC) associated with Peutz-Jeghers syndrome and elevated cancer risk: case report of a Chinese patient.
Author:	Zhao, Zi-Ye\|Jiang, Yu-Liang\|Li, Bai-Rong\|Yang, Fu\|Li, Jing\|Jin, Xiao-Wei\|Ning, Shou-Bin\|Sun, Shu-Han
PMID:	29141581

70.
Journal:	Asian J Surg. 2018 Sep;41(5):480-485.
Title:	Clinical manifestations and STK11 germline mutations in Taiwanese patients with Peutz-Jeghers syndrome.
Author:	Chiang, Jy-Ming\|Chen, Tse-Ching
PMID:	28869103

71.
Journal:	Surg Today. 2018 Aug;48(8):765-772.
Title:	APC:T1556fs and STK11 mutations in duodenal adenomas and adenocarcinomas.
Author:	Kojima, Yohei\|Ohtsuka, Kouki\|Ohnishi, Hiroaki\|Abe, Nobutsugu\|Furuse, Junji\|Watanabe, Takashi\|Sugiyama, Masanori
PMID:	29525853

72.
Journal:	Oncol Lett. 2018 Jul;16(1):1291-1297.
Title:	Liver kinase B1/adenosine monophosphate-activated protein kinase signaling axis induces p21/WAF1 expression in a p53-dependent manner.
Author:	Ma, Qing\|Xiao, Ping\|Sun, Linlin\|Wang, Jing\|Zhong, Diansheng
PMID:	29963200

73.
Journal:	Eur J Hum Genet. 2018 Jul 2. pii: 10.1038/s41431-018-0207-2.
Title:	Optimization of the diagnosis of inherited colorectal cancer using NGS and capture of exonic and intronic sequences of panel genes.
Author:	Baert-Desurmont, Stephanie\|Coutant, Sophie\|Charbonnier, Francoise\|Macquere, Pierre\|Lecoquierre, Francois\|Schwartz, Mathias\|Blanluet, Maud\|Vezain, Myriam\|Lanos, Raphael\|Quenez, Olivier\|Bou, Jacqueline\|Bouvignies, Emilie\|Fourneaux, Steeve\|Manase, Sandrine\|V
PMID:	29967336

74.
Journal:	Cancer Biol Ther. 2018 Oct 25:1-11.
Title:	Metformin inhibited colitis and colitis-associated cancer (CAC) through protecting mitochondrial structures of colorectal epithelial cells in mice.
Author:	Wang, Shu-Qing\|Cui, Shu-Xiang\|Qu, Xian-Jun
PMID:	30359174

75.
Journal:	J Physiol Biochem. 2018 Oct 25. pii: 10.1007/s13105-018-0651-z.
Title:	Sodium butyrate induces autophagy in colorectal cancer cells through LKB1/AMPK signaling.
Author:	Luo, Shunli\|Li, Ziyin\|Mao, Lianzhi\|Chen, Siqiang\|Sun, Suxia
PMID:	30362049