Primary Site >> Colorectal Cancer
Gene >> STAT6
| 1. | |||||||||||
| Journal: | J Immunol. 1996 Apr 15;156(8):2972-8. | ||||||||||
| Title: | IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. | ||||||||||
| Author: | Murata, T|Noguchi, P D|Puri, R K | ||||||||||
| PMID: | 8609418 | ||||||||||
| 2. | |||||||||||
| Journal: | Endocrinology. 1999 Oct;140(10):4573-84. | ||||||||||
| Title: | Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines. | ||||||||||
| Author: | Gingras, S|Simard, J | ||||||||||
| PMID: | 10499513 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2000 Apr 7;275(14):10212-7. | ||||||||||
| Title: | Interleukin-4 mediates cell growth inhibition through activation of Stat1. | ||||||||||
| Author: | Chang, T L|Peng, X|Fu, X Y | ||||||||||
| PMID: | 10744706 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Cell Endocrinol. 2001 Jan 22;171(1-2):25-40. | ||||||||||
| Title: | Crucial role of cytokines in sex steroid formation in normal and tumoral tissues. | ||||||||||
| Author: | Simard, J|Gingras, S | ||||||||||
| PMID: | 11165008 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Lett. 2006 Nov 8;243(1):38-46. Epub 2006 Jan 4. | ||||||||||
| Title: | STAT6 specific shRNA inhibits proliferation and induces apoptosis in colon cancer HT-29 cells. | ||||||||||
| Author: | Zhang, Mingsheng|Zhou, Yunfeng|Xie, Conghua|Zhou, Fuxiang|Chen, Yun|Han, Guang|Zhang, Wen Jie | ||||||||||
| PMID: | 16387423 | ||||||||||
| 6. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2006 Jan 10;86(2):76-81. | ||||||||||
| Title: | [Impact of STAT6 signaling pathway blockade on apoptosis of human colon cancer cells]. | ||||||||||
| Author: | Zhang, Ming-sheng|Zhou, Yun-feng|Xie, Cong-Hua|Zhang, Wen-jie|Zhou, Fu-xiang|Qu, Xue-ju | ||||||||||
| PMID: | 16620708 | ||||||||||
| 7. | |||||||||||
| Journal: | Chin Med J (Engl). 2006 May 20;119(10):801-8. | ||||||||||
| Title: | Apoptosis induced by short hairpin RNA-mediated STAT6 gene silencing in human colon cancer cells. | ||||||||||
| Author: | Zhang, Ming-sheng|Zhou, Yun-feng|Zhang, Wen-jie|Zhang, Xiao-lian|Pan, Qin|Ji, Xue-mei|Luo, Zhi-guo|Wu, Jian-ping | ||||||||||
| PMID: | 16732981 | ||||||||||
| 8. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2008 May 2;369(2):554-60. | ||||||||||
| Title: | IL-4/Stat6 activities correlate with apoptosis and metastasis in colon cancer cells. | ||||||||||
| Author: | Li, Ben Hui|Yang, Xian Zi|Li, Pin Dong|Yuan, Qin|Liu, Xiao Hong|Yuan, Jia|Zhang, Wen Jie | ||||||||||
| PMID: | 18294957 | ||||||||||
| 9. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2009 Jan;135(1):131-40. | ||||||||||
| Title: | Differential IL-4/Stat6 activities correlate with differential expression of regulatory genes SOCS-1, SHP-1, and PP2A in colon cancer cells. | ||||||||||
| Author: | Yuan, Qin|Li, Pin Dong|Li, Ben Hui|Yang, Xian Zi|Xu, Shuang Bing|Liu, Xiao Hong|Zhou, Fu Xiang|Zhang, Wen Jie | ||||||||||
| PMID: | 18536936 | ||||||||||
| 10. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2009 Dec;135(12):1791-8. | ||||||||||
| Title: | DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. | ||||||||||
| Author: | Xu, Shuang Bing|Liu, Xiao Hong|Li, Ben Hui|Zhang, Yan|Yuan, Jia|Yuan, Qin|Li, Pin Dong|Yang, Xian Zi|Li, Feng|Zhang, Wen Jie | ||||||||||
| PMID: | 19551406 | ||||||||||
| 11. | |||||||||||
| Journal: | J Interferon Cytokine Res. 2009 Dec;29(12):809-16. | ||||||||||
| Title: | Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells. | ||||||||||
| Author: | Liu, Xiao Hong|Xu, Shuang Bing|Yuan, Jia|Li, Ben Hui|Zhang, Yan|Yuan, Qin|Li, Pin Dong|Li, Feng|Zhang, Wen Jie | ||||||||||
| PMID: | 19929568 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Cancer. 2010 Apr 1;126(7):1666-74. | ||||||||||
| Title: | Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells. | ||||||||||
| Author: | Takaku, Shun|Terabe, Masaki|Ambrosino, Elena|Peng, Judy|Lonning, Scott|McPherson, John M|Berzofsky, Jay A | ||||||||||
| PMID: | 19830696 | ||||||||||
| 13. | |||||||||||
| Journal: | Inflamm Bowel Dis. 2010 May;16(5):753-64. | ||||||||||
| Title: | Elevated IL-13Ralpha2 in intestinal epithelial cells from ulcerative colitis or colorectal cancer initiates MAPK pathway. | ||||||||||
| Author: | Mandal, Debasmita|Levine, Alan D | ||||||||||
| PMID: | 20014020 | ||||||||||
| 14. | |||||||||||
| Journal: | World J Gastroenterol. 2010 May 21;16(19):2421-7. | ||||||||||
| Title: | EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis. | ||||||||||
| Author: | Wang, Cheng-Gang|Ye, Ying-Jiang|Yuan, Jing|Liu, Fang-Fang|Zhang, Hui|Wang, Shan | ||||||||||
| PMID: | 20480530 | ||||||||||
| 15. | |||||||||||
| Journal: | J Cell Physiol. 2010 Nov;225(2):555-61. | ||||||||||
| Title: | Survivin is regulated by interleukin-4 in colon cancer stem cells. | ||||||||||
| Author: | Di Stefano, A B|Iovino, F|Lombardo, Y|Eterno, V|Hoger, T|Dieli, F|Stassi, G|Todaro, M | ||||||||||
| PMID: | 20506498 | ||||||||||
| 16. | |||||||||||
| Journal: | Eur J Immunol. 2012 Aug;42(8):2052-9. | ||||||||||
| Title: | Tumor-induced myeloid-derived suppressor cell function is independent of IFN-gamma and IL-4Ralpha. | ||||||||||
| Author: | Sinha, Pratima|Parker, Katherine H|Horn, Lucas|Ostrand-Rosenberg, Suzanne | ||||||||||
| PMID: | 22673957 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Lett. 2012 Sep 1;322(1):92-7. | ||||||||||
| Title: | Interleukin-12 inhibits the survival of human colon cancer stem cells in vitro and their tumor initiating capacity in mice. | ||||||||||
| Author: | Yin, Xiao-ling|Wang, Ning|Wei, Xing|Xie, Gan-feng|Li, Jian-jun|Liang, Hou-jie | ||||||||||
| PMID: | 22366581 | ||||||||||
| 18. | |||||||||||
| Journal: | Cell Signal. 2012 Mar;24(3):718-25. | ||||||||||
| Title: | Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo. | ||||||||||
| Author: | Li, Ben Hui|Xu, Shuang Bing|Li, Feng|Zou, Xiao Guang|Saimaiti, Abudukeyoumu|Simayi, Dilixia|Wang, Ying Hong|Zhang, Yan|Yuan, Jia|Zhang, Wen Jie | ||||||||||
| PMID: | 22108090 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Carcinog. 2013 Feb;52(2):155-66. | ||||||||||
| Title: | JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Kadlubar, Susan A|Bondurant, Kristina L|Wolff, Roger K | ||||||||||
| PMID: | 22121102 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncotarget. 2016 Sep 20;7(38):61183-61198. | ||||||||||
| Title: | IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells. | ||||||||||
| Author: | Cao, Hui|Zhang, Jing|Liu, Hong|Wan, Ledong|Zhang, Honghe|Huang, Qiong|Xu, Enping|Lai, Maode | ||||||||||
| PMID: | 27533463 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 29;7(48):78726-78735. | ||||||||||
| Title: | MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway. | ||||||||||
| Author: | Chen, Wankun|Xu, Yajun|Zhong, Jing|Wang, Huihui|Weng, Meilin|Cheng, Qian|Wu, Qichao|Sun, Zhirong|Jiang, Hui|Zhu, Minmin|Ren, Yu|Xu, Pingbo|Chen, Jiawei|Miao, Changhong | ||||||||||
| PMID: | 27783989 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Lett. 2017 Mar 1;388:43-53. | ||||||||||
| Title: | The involvement of M2 macrophage polarization inhibition in fenretinide-mediated chemopreventive effects on colon cancer. | ||||||||||
| Author: | Dong, Rong|Gong, Yanling|Meng, Wen|Yuan, Meng|Zhu, Hong|Ying, Meidan|He, Qiaojun|Cao, Ji|Yang, Bo | ||||||||||
| PMID: | 27913199 | ||||||||||
| 23. | |||||||||||
| Journal: | Biochimie. 2017 Apr;135:154-163. | ||||||||||
| Title: | Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells. | ||||||||||
| Author: | Mohamad Fairus, A K|Choudhary, B|Hosahalli, S|Kavitha, N|Shatrah, O | ||||||||||
| PMID: | 28196676 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Immunol Res. 2017 May;5(5):385-396. | ||||||||||
| Title: | Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer. | ||||||||||
| Author: | Leon-Cabrera, Sonia A|Molina-Guzman, Emmanuel|Delgado-Ramirez, Yael G|Vazquez-Sandoval, Armando|Ledesma-Soto, Yadira|Perez-Plasencia, Carlos G|Chirino, Yolanda I|Delgado-Buenrostro, Norma L|Rodriguez-Sosa, Miriam|Vaca-Paniagua, Felipe|Avila-Moreno, Federi | ||||||||||
| PMID: | 28385737 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Cell. 2017 Apr 10;31(4):563-575.e5. | ||||||||||
| Title: | Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. | ||||||||||
| Author: | Poh, Ashleigh R|Love, Christopher G|Masson, Frederick|Preaudet, Adele|Tsui, Cary|Whitehead, Lachlan|Monard, Simon|Khakham, Yelena|Burstroem, Lotta|Lessene, Guillaume|Sieber, Oliver|Lowell, Clifford|Putoczki, Tracy L|O'Donoghue, Robert J J|Ernst, Matthias | ||||||||||
| PMID: | 28399411 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):38113-38135. | ||||||||||
| Title: | Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells. | ||||||||||
| Author: | Liu, Han|Antony, Smitha|Roy, Krishnendu|Juhasz, Agnes|Wu, Yongzhong|Lu, Jiamo|Meitzler, Jennifer L|Jiang, Guojian|Polley, Eric|Doroshow, James H | ||||||||||
| PMID: | 28498822 | ||||||||||
| 27. | |||||||||||
| Journal: | Neoplasia. 2017 Aug;19(8):595-605. | ||||||||||
| Title: | Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response. | ||||||||||
| Author: | Jayakumar, Asha|Bothwell, Alfred L M | ||||||||||
| PMID: | 28654863 | ||||||||||
| 28. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2017 Sep 9;491(1):159-165. | ||||||||||
| Title: | Inhibition of IL-6/STAT3 signaling in human cancer cells using Evista. | ||||||||||
| Author: | Shi, Wei|Yan, Dan|Zhao, Chongqiang|Xiao, Miaomiao|Wang, Yina|Ma, Haiyan|Liu, Tianshu|Qin, Hua|Zhang, Cuntai|Li, Chenglong|Lin, Jiayuh|Li, Sheng|Lv, Jiagao|Lin, Li | ||||||||||
| PMID: | 28711499 | ||||||||||
| 29. | |||||||||||
| Journal: | J Crohns Colitis. 2018 Apr 27;12(5):589-599. | ||||||||||
| Title: | CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease. | ||||||||||
| Author: | Salvador, Pedro|Macias-Ceja, Dulce Carolina|Gisbert-Ferrandiz, Laura|Hernandez, Carlos|Bernardo, David|Alos, Rafael|Navarro-Vicente, Francisco|Esplugues, Juan Vicente|Ortiz-Masia, Dolores|Barrachina, Maria Dolores|Calatayud, Sara | ||||||||||
| PMID: | 29304229 | ||||||||||
| 30. | |||||||||||
| Journal: | Cell Physiol Biochem. 2018;45(2):808-818. | ||||||||||
| Title: | Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells. | ||||||||||
| Author: | Wu, Zhong|Liu, Jie|Hu, Siyuan|Zhu, Yuchang|Li, Shaohua | ||||||||||
| PMID: | 29414823 | ||||||||||
| 31. | |||||||||||
| Journal: | Cell Biol Int. 2018 Aug;42(8):985-993. | ||||||||||
| Title: | Propofol prevents IL-13-induced epithelial-mesenchymal transition in human colorectal cancer cells. | ||||||||||
| Author: | Xu, Kejia|Tao, Weimin|Su, Zhe | ||||||||||
| PMID: | 29569786 | ||||||||||
| 32. | |||||||||||
| Journal: | Int J Oncol. 2018 Aug;53(2):567-578. | ||||||||||
| Title: | E2F1/SP3/STAT6 axis is required for IL-4-induced epithelial-mesenchymal transition of colorectal cancer cells. | ||||||||||
| Author: | Chen, Jiaoe|Gong, Chaoju|Mao, Huiqin|Li, Zhaoyun|Fang, Zejun|Chen, Qiang|Lin, Min|Jiang, Xiang|Hu, Yanyan|Wang, Wei|Zhang, Xiaomin|Chen, Xianjun|Li, Hongzhang | ||||||||||
| PMID: | 29901191 | ||||||||||