Primary Site >> Colorectal Cancer
Gene >> STAT6
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Ref: IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. PMID: 8609418 |
Ref: Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines. PMID: 10499513 |
Ref: Interleukin-4 mediates cell growth inhibition through activation of Stat1. PMID: 10744706 |
Ref: Crucial role of cytokines in sex steroid formation in normal and tumoral tissues. PMID: 11165008 |
Ref: STAT6 specific shRNA inhibits proliferation and induces apoptosis in colon cancer HT-29 cells. PMID: 16387423 Ref: [Impact of STAT6 signaling pathway blockade on apoptosis of human colon cancer cells]. PMID: 16620708 Ref: Apoptosis induced by short hairpin RNA-mediated STAT6 gene silencing in human colon cancer cells. PMID: 16732981 |
Ref: IL-4/Stat6 activities correlate with apoptosis and metastasis in colon cancer cells. PMID: 18294957 |
Ref: Differential IL-4/Stat6 activities correlate with differential expression of regulatory genes SOCS-1, SHP-1, and PP2A in colon cancer cells. PMID: 18536936 Ref: DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. PMID: 19551406 Ref: Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells. PMID: 19929568 |
Ref: Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells. PMID: 19830696 Ref: Elevated IL-13Ralpha2 in intestinal epithelial cells from ulcerative colitis or colorectal cancer initiates MAPK pathway. PMID: 20014020 Ref: EZH2 and STAT6 expression profiles are correlated with colorectal cancer stage and prognosis. PMID: 20480530 Ref: Survivin is regulated by interleukin-4 in colon cancer stem cells. PMID: 20506498 |
Ref: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo. PMID: 22108090 Ref: Interleukin-12 inhibits the survival of human colon cancer stem cells in vitro and their tumor initiating capacity in mice. PMID: 22366581 Ref: Tumor-induced myeloid-derived suppressor cell function is independent of IFN-gamma and IL-4Ralpha. PMID: 22673957 |
Ref: JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. PMID: 22121102 |
Ref: IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells. PMID: 27533463 Ref: MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway. PMID: 27783989 |
Ref: The involvement of M2 macrophage polarization inhibition in fenretinide-mediated chemopreventive effects on colon cancer. PMID: 27913199 Ref: Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells. PMID: 28196676 Ref: Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer. PMID: 28385737 Ref: Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. PMID: 28399411 Ref: Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells. PMID: 28498822 Ref: Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response. PMID: 28654863 Ref: Inhibition of IL-6/STAT3 signaling in human cancer cells using Evista. PMID: 28711499 |
Ref: CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease. PMID: 29304229 Ref: Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells. PMID: 29414823 Ref: Propofol prevents IL-13-induced epithelial-mesenchymal transition in human colorectal cancer cells. PMID: 29569786 Ref: E2F1/SP3/STAT6 axis is required for IL-4-induced epithelial-mesenchymal transition of colorectal cancer cells. PMID: 29901191 |