Primary Site >> Colorectal Cancer

Gene >> STAT5A

Journal: J Immunol. 1996 Apr 15;156(8):2972-8.
Title: IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling.
Author: Murata, T|Noguchi, P D|Puri, R K
PMID: 8609418
Journal: Zhonghua Yi Xue Za Zhi. 2005 Sep 21;85(36):2566-9.
Title: [Molecular mechanism of cyclooxygenase-2 inhibitor in inhibition of proliferation of colon cancer cells by modulating Stat5 signal transduction pathway].
Author: Ma, Xiang-tao|Yu, Li-wei|Wang, Shan|Zhang, Hui|Du, Ru-yu|Cui, Zhi-rong
PMID: 16321305
Journal: Gut. 2007 Jan;56(1):73-81. Epub 2006 Jun 15.
Title: Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis.
Author: Han, X|Benight, N|Osuntokun, B|Loesch, K|Frank, S J|Denson, L A
PMID: 16777921
Journal: Lab Invest. 2009 Jun;89(6):717-25.
Title: Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells.
Author: Xiong, Hua|Su, Wen-Yu|Liang, Qin-Chuan|Zhang, Zhi-Gang|Chen, Hui-Min|Du, Wan|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 19290007
Journal: J Cell Mol Med. 2009 Sep;13(9B):3668-79.
Title: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.
Author: Xiong, Hua|Chen, Zhao-Fei|Liang, Qin-Chuan|Du, Wan|Chen, Hui-Min|Su, Wen-Yu|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan
PMID: 20196786
Journal: Eur J Immunol. 2010 May;40(5):1396-407.
Title: Interleukin-4 downregulates CD127 expression and activity on human thymocytes and mature CD8+ T cells.
Author: Crawley, Angela M|Vranjkovic, Agatha|Young, Charlene|Angel, Jonathan B
PMID: 20201040
Journal: Mol Biol Cell. 2010 Jul 1;21(13):2338-54.
Title: A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.
Author: Ghosh, Pradipta|Beas, Anthony O|Bornheimer, Scott J|Garcia-Marcos, Mikel|Forry, Erin P|Johannson, Carola|Ear, Jason|Jung, Barbara H|Cabrera, Betty|Carethers, John M|Farquhar, Marilyn G
PMID: 20462955
Journal: Int J Colorectal Dis. 2011 Jan;26(1):29-35.
Title: Expression of phosphorylated Stat5 predicts expression of cyclin D1 and correlates with poor prognosis of colonic adenocarcinoma.
Author: Mao, Yinling|Li, Zhiwei|Lou, Changjie|Zhang, Yanqiao
PMID: 21079973
Journal: Pathol Oncol Res. 2011 Jun;17(2):333-9.
Title: Phospho-STAT5 expression is associated with poor prognosis of human colonic adenocarcinoma.
Author: Mao, Yin-Ling|Li, Zhi-Wei|Lou, Chang-Jie|Pang, Da|Zhang, Yan-Qiao
PMID: 21234733
Journal: J Cell Physiol. 2012 Jun;227(6):2421-9.
Title: STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.
Author: Du, Wan|Wang, Ying-Chao|Hong, Jie|Su, Wen-Yu|Lin, Yan-Wei|Lu, Rong|Xiong, Hua|Fang, Jing-Yuan
PMID: 21826656
Journal: Mol Cancer Ther. 2012 Apr;11(4):984-93.
Title: Therapeutic efficacy of CEP-33779, a novel selective JAK2 inhibitor, in a mouse model of colitis-induced colorectal cancer.
Author: Seavey, Matthew M|Lu, Lily D|Stump, Kristine L|Wallace, Nate H|Hockeimer, William|O'Kane, Teresa M|Ruggeri, Bruce A|Dobrzanski, Pawel
PMID: 22334590
Journal: Mol Med Rep. 2012 May;5(5):1215-9.
Title: STAT5a-targeting miRNA enhances chemosensitivity to cisplatin and 5-fluorouracil in human colorectal cancer cells.
Author: Hong, Xuan|Chen, Gongyan|Wang, Meng|Lou, Changjie|Mao, Yinling|Li, Zhiwei|Zhang, Yanqiao
PMID: 22367509
Journal: Mol Cancer. 2012 Jun 8;11:38.
Title: Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer.
Author: Nelson, Laura D|Bender, Christian|Mannsperger, Heiko|Buergy, Daniel|Kambakamba, Patryk|Mudduluru, Giridhar|Korf, Ulrike|Hughes, Dennis|Van Dyke, Michael W|Allgayer, Heike
PMID: 22682314
Journal: Cancer Cell. 2012 Jul 10;22(1):91-105.
Title: Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway.
Author: Wolf, Monika Julia|Hoos, Alexandra|Bauer, Judith|Boettcher, Steffen|Knust, Markus|Weber, Achim|Simonavicius, Nicole|Schneider, Christoph|Lang, Matthias|Sturzl, Michael|Croner, Roland S|Konrad, Andreas|Manz, Markus G|Moch, Holger|Aguzzi, Adriano|van Loo, G
PMID: 22789541
Journal: Asian Pac J Cancer Prev. 2012;13(5):2235-40.
Title: c-Src antisense complexed with PAMAM denderimes decreases of c-Src expression and EGFR-dependent downstream genes in the human HT-29 colon cancer cell line.
Author: Nourazarian, Ali Reza|Pashaei-Asl, Roghiyeh|Omidi, Yadollah|Najar, Ahmad Gholamhoseinian
PMID: 22901200
Journal: Asian Pac J Cancer Prev. 2012;13(9):4751-6.
Title: Combined EGFR and c-Src antisense oligodeoxynucleotides encapsulated with PAMAM Denderimers inhibit HT-29 colon cancer cell proliferation.
Author: Nourazarian, Ali Reza|Najar, Ahmad Gholamhoseinian|Farajnia, Safar|Khosroushahi, Ahmad Yari|Pashaei-Asl, Roghiyeh|Omidi, Yadollah
PMID: 23167414
Journal: Acta Biochim Pol. 2012;59(4):467-74. Epub 2012 Nov 21.
Title: The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment.
Author: Tokarz, Paulina|Blasiak, Janusz
PMID: 23173124
Journal: Mol Carcinog. 2013 Feb;52(2):155-66.
Title: JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Kadlubar, Susan A|Bondurant, Kristina L|Wolff, Roger K
PMID: 22121102
Journal: Asian Pac J Cancer Prev. 2013;14(1):495-8.
Title: EGFR antisense oligonucleotides encapsulated with nanoparticles decrease EGFR, MAPK1 and STAT5 expression in a human colon cancer cell line.
Author: Najar, Ahmad Gholamhoseinian|Pashaei-Asl, Roghiyeh|Omidi, Yadollah|Farajnia, Safar|Nourazarian, Ali Reza
PMID: 23534780
Journal: J Gastroenterol. 2014 Oct;49(10):1378-91.
Title: Functions and regulation of MUC13 mucin in colon cancer cells.
Author: Gupta, Brij K|Maher, Diane M|Ebeling, Mara C|Stephenson, Phillip D|Puumala, Susan E|Koch, Michael R|Aburatani, Hiroyuki|Jaggi, Meena|Chauhan, Subhash C
PMID: 24097071
Journal: Carcinogenesis. 2014 Jun;35(6):1330-40.
Title: IL-23 selectively promotes the metastasis of colorectal carcinoma cells with impaired Socs3 expression via the STAT5 pathway.
Author: Zhang, Le|Li, Jun|Li, Li|Zhang, Jie|Wang, Xiaodong|Yang, Chuanhua|Li, Yanyan|Lan, Feng|Lin, Ping
PMID: 24464786
Journal: Int J Mol Med. 2014 Apr;33(4):1019-26.
Title: Integrative genomic analyses of the histamine H1 receptor and its role in cancer prediction.
Author: Wang, Minghai|Wei, Xiaolong|Shi, Lianghui|Chen, Bin|Zhao, Guohai|Yang, Haiwei
PMID: 24535227
Journal: Carcinogenesis. 2014 Jun;35(6):1389-98.
Title: Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, beta-catenin and EZH2.
Author: Weng, Yu-Rong|Yu, Ya-Nan|Ren, Lin-Lin|Cui, Yun|Lu, You-Yong|Chen, Hao-Yan|Ma, Xiong|Qin, Wen-Xin|Cao, Weibiao|Hong, Jie|Fang, Jing-Yuan
PMID: 24608043
Journal: Cancer Res. 2014 Nov 1;74(21):6341-51.
Title: Holo-retinol-binding protein and its receptor STRA6 drive oncogenic transformation.
Author: Berry, Daniel C|Levi, Liraz|Noy, Noa
PMID: 25237067
Journal: Oncotarget. 2015 Oct 13;6(31):32013-26.
Title: Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment.
Author: Yu, Ya-Nan|Yu, Ta-Chung|Zhao, Hui-Jun|Sun, Tian-Tian|Chen, Hui-Min|Chen, Hao-Yan|An, Hui-Fang|Weng, Yu-Rong|Yu, Jun|Li, Min|Qin, Wen-Xin|Ma, Xiong|Shen, Nan|Hong, Jie|Fang, Jing-Yuan
PMID: 26397137
Journal: Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1548-55.
Title: Expressional STAT3/STAT5 Ratio is an Independent Prognostic Marker in Colon Carcinoma.
Author: Klupp, Fee|Diers, Johannes|Kahlert, Christoph|Neumann, Lena|Halama, Niels|Franz, Clemens|Schmidt, Thomas|Lasitschka, Felix|Warth, Arne|Weitz, Juergen|Koch, Moritz|Schneider, Martin|Ulrich, Alexis
PMID: 25773877
Journal: Mol Cancer Res. 2015 Feb;13(2):281-92.
Title: Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis.
Author: Hu, Ying|Chau, Thinh|Liu, Hui-Xin|Liao, Degui|Keane, Ryan|Nie, Yuqiang|Yang, Hui|Wan, Yu-Jui Yvonne
PMID: 25232032
Journal: Oncogene. 2016 Feb 25;35(8):939-51.
Title: Targeting JAK kinase in solid tumors: emerging opportunities and challenges.
Author: Buchert, M|Burns, C J|Ernst, M
PMID: 25982279
Journal: Hum Immunol. 2017 Feb;78(2):129-137.
Title: Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E2.
Author: Moltu, Kristine|Henjum, Karen|Oberprieler, Nikolaus G|Bjornbeth, Bjorn A|Tasken, Kjetil
PMID: 27769746
Journal: Open Biol. 2017 Nov;7(11). pii: rsob.170169.
Title: Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions.
Author: Yuan, Ruoshi|Zhang, Suzhan|Yu, Jiekai|Huang, Yanqin|Lu, Demin|Cheng, Runtan|Huang, Sui|Ao, Ping|Zheng, Shu|Hood, Leroy|Zhu, Xiaomei
PMID: 29118272
Journal: Oncoimmunology. 2017 Nov 13;7(2):e1393597.
Title: Enhancement of antibody-dependent cellular cytotoxicity of cetuximab by a chimeric protein encompassing interleukin-15.
Author: Ochoa, Maria Carmen|Minute, Luna|Lopez, Ascension|Perez-Ruiz, Elisabeth|Gomar, Celia|Vasquez, Marcos|Inoges, Susana|Etxeberria, Inaki|Rodriguez, Inmaculada|Garasa, Saray|Mayer, Jan-Peter Andreas|Wirtz, Peter|Melero, Ignacio|Berraondo, Pedro
PMID: 29308327
Journal: Cell Physiol Biochem. 2018;45(2):808-818.
Title: Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells.
Author: Wu, Zhong|Liu, Jie|Hu, Siyuan|Zhu, Yuchang|Li, Shaohua
PMID: 29414823
Journal: Nat Med. 2018 Mar;24(3):262-270.
Title: DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation.
Author: Xiao, Qian|Wu, Jibo|Wang, Wei-Jia|Chen, Shiyang|Zheng, Yingxia|Yu, Xiaoqing|Meeth, Katrina|Sahraei, Mahnaz|Bothwell, Alfred L M|Chen, Lieping|Bosenberg, Marcus|Chen, Jianfeng|Sexl, Veronika|Sun, Le|Li, Lin|Tang, Wenwen|Wu, Dianqing
PMID: 29431745
Journal: FASEB J. 2018 Oct;32(10):5365-5377.
Title: Angiogenin and the MMP9-TIMP2 axis are up-regulated in proangiogenic, decidual NK-like cells from patients with colorectal cancer.
Author: Bruno, Antonino|Bassani, Barbara|D'Urso, Davide Giuseppe|Pitaku, Ilvana|Cassinotti, Elisa|Pelosi, Giuseppe|Boni, Luigi|Dominioni, Lorenzo|Noonan, Douglas M|Mortara, Lorenzo|Albini, Adriana
PMID: 29763380
Journal: J Immunol Res. 2018 Jun 14;2018:6985031.
Title: STAT5 and TET2 Cooperate to Regulate FOXP3-TSDR Demethylation in CD4(+) T Cells of Patients with Colorectal Cancer.
Author: Ma, Hulin|Gao, Weishi|Sun, Xiaoxia|Wang, Weixing
PMID: 30013992