Primary Site >> Colorectal Cancer
Gene >> STAT5A
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Ref: IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. PMID: 8609418 |
Ref: [Molecular mechanism of cyclooxygenase-2 inhibitor in inhibition of proliferation of colon cancer cells by modulating Stat5 signal transduction pathway]. PMID: 16321305 |
Ref: Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis. PMID: 16777921 |
Ref: Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells. PMID: 19290007 Ref: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling. PMID: 20196786 |
Ref: Interleukin-4 downregulates CD127 expression and activity on human thymocytes and mature CD8+ T cells. PMID: 20201040 Ref: A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate. PMID: 20462955 |
Ref: Expression of phosphorylated Stat5 predicts expression of cyclin D1 and correlates with poor prognosis of colonic adenocarcinoma. PMID: 21079973 Ref: Phospho-STAT5 expression is associated with poor prognosis of human colonic adenocarcinoma. PMID: 21234733 |
Ref: STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species. PMID: 21826656 Ref: Therapeutic efficacy of CEP-33779, a novel selective JAK2 inhibitor, in a mouse model of colitis-induced colorectal cancer. PMID: 22334590 Ref: STAT5a-targeting miRNA enhances chemosensitivity to cisplatin and 5-fluorouracil in human colorectal cancer cells. PMID: 22367509 Ref: Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer. PMID: 22682314 Ref: Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway. PMID: 22789541 Ref: c-Src antisense complexed with PAMAM denderimes decreases of c-Src expression and EGFR-dependent downstream genes in the human HT-29 colon cancer cell line. PMID: 22901200 Ref: Combined EGFR and c-Src antisense oligodeoxynucleotides encapsulated with PAMAM Denderimers inhibit HT-29 colon cancer cell proliferation. PMID: 23167414 Ref: The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment. PMID: 23173124 |
Ref: JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. PMID: 22121102 Ref: EGFR antisense oligonucleotides encapsulated with nanoparticles decrease EGFR, MAPK1 and STAT5 expression in a human colon cancer cell line. PMID: 23534780 |
Ref: Functions and regulation of MUC13 mucin in colon cancer cells. PMID: 24097071 Ref: IL-23 selectively promotes the metastasis of colorectal carcinoma cells with impaired Socs3 expression via the STAT5 pathway. PMID: 24464786 Ref: Integrative genomic analyses of the histamine H1 receptor and its role in cancer prediction. PMID: 24535227 Ref: Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, beta-catenin and EZH2. PMID: 24608043 Ref: Holo-retinol-binding protein and its receptor STRA6 drive oncogenic transformation. PMID: 25237067 |
Ref: Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis. PMID: 25232032 Ref: Expressional STAT3/STAT5 Ratio is an Independent Prognostic Marker in Colon Carcinoma. PMID: 25773877 Ref: Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment. PMID: 26397137 |
Ref: Targeting JAK kinase in solid tumors: emerging opportunities and challenges. PMID: 25982279 |
Ref: Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E2. PMID: 27769746 Ref: Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions. PMID: 29118272 |
Ref: Enhancement of antibody-dependent cellular cytotoxicity of cetuximab by a chimeric protein encompassing interleukin-15. PMID: 29308327 Ref: Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells. PMID: 29414823 Ref: DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation. PMID: 29431745 Ref: Angiogenin and the MMP9-TIMP2 axis are up-regulated in proangiogenic, decidual NK-like cells from patients with colorectal cancer. PMID: 29763380 Ref: STAT5 and TET2 Cooperate to Regulate FOXP3-TSDR Demethylation in CD4(+) T Cells of Patients with Colorectal Cancer. PMID: 30013992 |