Literatures

Primary Site >> Pancreatic Cancer

Gene >> STAT3

1.
Journal:	Ann Surg Oncol. 1998 Oct-Nov;5(7):642-9.
Title:	Interferon-mediated activation of the STAT signaling pathway in a human carcinoid tumor.
Author:	Wang, S\|Tyring, S K\|Townsend, C M Jr\|Evers, B M
PMID:	9831114

2.
Journal:	FASEB J. 2001 Mar;15(3):562-4. Epub 2001 Jan 19.
Title:	Proteolysis-inducing factor regulates hepatic gene expression via the transcription factors NF-(kappa)B and STAT3.
Author:	Watchorn, T M\|Waddell, I\|Dowidar, N\|Ross, J A
PMID:	11259367

3.
Journal:	Gastroenterology. 2002 Dec;123(6):2052-63.
Title:	Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis.
Author:	Greten, Florian R\|Weber, Christoph K\|Greten, Tim F\|Schneider, Gunter\|Wagner, Martin\|Adler, Guido\|Schmid, Roland M
PMID:	12454861

4.
Journal:	Oncogene. 2003 Jan 23;22(3):319-29.
Title:	Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
Author:	Wei, Daoyan\|Le, Xiangdong\|Zheng, Leizhen\|Wang, Liwei\|Frey, Jennifer A\|Gao, Allen C\|Peng, Zhihai\|Huang, Suyun\|Xiong, Henry Q\|Abbruzzese, James L\|Xie, Keping
PMID:	12545153

5.
Journal:	Gastroenterology. 2003 Sep;125(3):891-905.
Title:	Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer.
Author:	Scholz, Arne\|Heinze, Sandra\|Detjen, Katharina M\|Peters, Michael\|Welzel, Martina\|Hauff, Peter\|Schirner, Michael\|Wiedenmann, Bertram\|Rosewicz, Stefan
PMID:	12949733

6.
Journal:	Cancer Lett. 2003 Nov 10;201(1):107-16.
Title:	Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
Author:	Toyonaga, Takayuki\|Nakano, Kenji\|Nagano, Masahiro\|Zhao, Gang\|Yamaguchi, Koji\|Kuroki, Syoji\|Eguchi, Takashi\|Chijiiwa, Kazuo\|Tsuneyoshi, Masazumi\|Tanaka, Masao
PMID:	14580692

7.
Journal:	Oncogene. 2003 Oct 30;22(49):7781-95.
Title:	Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
Author:	DeArmond, Daniel\|Brattain, Michael G\|Jessup, John Milburn\|Kreisberg, Jeffrey\|Malik, Shazli\|Zhao, Shujie\|Freeman, James W
PMID:	14586404

8.
Journal:	Anticancer Res. 2004 Jan-Feb;24(1):133-7.
Title:	Modulation of the constitutive activated STAT3 transcription factor in pancreatic cancer prevention: effects of indole-3-carbinol (I3C) and genistein.
Author:	Lian, Jian P\|Word, Beverly\|Taylor, Skeetora\|Hammons, George J\|Lyn-Cook, Beverly D
PMID:	15015587

9.
Journal:	J Biol Chem. 2005 Mar 18;280(11):10710-5. Epub 2005 Jan 7.
Title:	A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models.
Author:	Ferrand, Audrey\|Kowalski-Chauvel, Aline\|Bertrand, Claudine\|Escrieut, Chantal\|Mathieu, Anne\|Portolan, Ghislaine\|Pradayrol, Lucien\|Fourmy, Daniel\|Dufresne, Marlene\|Seva, Catherine
PMID:	15640156

10.
Journal:	Br J Cancer. 2005 Mar 14;92(5):921-8.
Title:	Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions.
Author:	Prokopchuk, O\|Liu, Y\|Henne-Bruns, D\|Kornmann, M
PMID:	15714203

11.
Journal:	Cancer Res. 2005 Feb 15;65(4):1497-504.
Title:	Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenograf
Author:	Yau, Cindy Y F\|Wheeler, Jeffery J\|Sutton, Kymberley L\|Hedley, David W
PMID:	15735038

12.
Journal:	Cancer Res. 2005 Apr 1;65(7):2861-71.
Title:	Farnesyl transferase inhibitor (R115777)-induced inhibition of STAT3(Tyr705) phosphorylation in human pancreatic cancer cell lines require extracellular signal-regulated kinases.
Author:	Venkatasubbarao, Kolaparthi\|Choudary, Ahsan\|Freeman, James W
PMID:	15805288

13.
Journal:	Mol Ther. 2005 May;11(5):724-33.
Title:	mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
Author:	Chada, Sunil\|Bocangel, Dora\|Ramesh, Rajagopal\|Grimm, Elizabeth A\|Mumm, John B\|Mhashilkar, Abner M\|Zheng, Mingzhong
PMID:	15851011

14.
Journal:	Cytokine Growth Factor Rev. 2006 Jun;17(3):147-56.
Title:	Transcriptional anti-angiogenesis therapy of human pancreatic cancer.
Author:	Xie, Keping\|Wei, Daoyan\|Huang, Suyun
PMID:	16516532

15.
Journal:	Mol Cancer Ther. 2006 Mar;5(3):621-9.
Title:	Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.
Author:	Kotha, Anupama\|Sekharam, Madhavi\|Cilenti, Lucia\|Siddiquee, Khandaker\|Khaled, Annette\|Zervos, Antonis S\|Carter, Bradford\|Turkson, James\|Jove, Richard
PMID:	16546976

16.
Journal:	Genes Dev. 2006 Jun 1;20(11):1435-40.
Title:	Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation.
Author:	Miyatsuka, Takeshi\|Kaneto, Hideaki\|Shiraiwa, Toshihiko\|Matsuoka, Taka-aki\|Yamamoto, Kaoru\|Kato, Ken\|Nakamura, Yumiko\|Akira, Shizuo\|Takeda, Kiyoshi\|Kajimoto, Yoshitaka\|Yamasaki, Yoshimitsu\|Sandgren, Eric P\|Kawaguchi, Yoshiya\|Wright, Christopher V E\|Fujitan
PMID:	16751181

17.
Journal:	Angiogenesis. 2006;9(2):101-10. Epub 2006 Jul 27.
Title:	Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells.
Author:	Trevino, Jose G\|Gray, Michael J\|Nawrocki, Steffan T\|Summy, Justin M\|Lesslie, Donald P\|Evans, Douglas B\|Sawyer, Tomi K\|Shakespeare, William C\|Watowich, Stephanie S\|Chiao, Paul J\|McConkey, David J\|Gallick, Gary E
PMID:	16871430

18.
Journal:	Anticancer Drugs. 2006 Oct;17(9):1045-56.
Title:	RP101 improves the efficacy of chemotherapy in pancreas carcinoma cell lines and pancreatic cancer patients.
Author:	Fahrig, Rudolf\|Quietzsch, Detlef\|Heinrich, Jorg-Christian\|Heinemann, Volker\|Boeck, Stefan\|Schmid, Roland M\|Praha, Christian\|Liebert, Andreas\|Sonntag, Denise\|Krupitza, Georg\|Hanel, Mathias
PMID:	17001178

19.
Journal:	Cancer Sci. 2006 Dec;97(12):1417-23. Epub 2006 Oct 19.
Title:	Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro.
Author:	Huang, Chen\|Cao, Jun\|Huang, Ke J\|Zhang, Fang\|Jiang, Tao\|Zhu, Lin\|Qiu, Zheng J
PMID:	17054436

20.
Journal:	Zhonghua Zhong Liu Za Zhi. 2006 Dec;28(12):890-3.
Title:	[Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro].
Author:	Huang, Chen\|Qiu, Zheng-Jun\|Cao, Jun\|Huang, Ke-Jian\|Zhang, Fang\|Jiang, Tao\|Zhu, Lin\|Liu, Jun
PMID:	17533737

21.
Journal:	Int J Mol Med. 2007 Feb;19(2):273-8.
Title:	STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review).
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	17203201

22.
Journal:	Int J Oncol. 2007 Apr;30(4):977-83.
Title:	Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression.
Author:	Kamohara, Hidenobu\|Ogawa, Michio\|Ishiko, Takatoshi\|Sakamoto, Kiyoshi\|Baba, Hideo
PMID:	17332938

23.
Journal:	Cancer Biol Ther. 2007 Apr;6(4):548-54.
Title:	ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib.
Author:	Frolov, Andrey\|Schuller, Kyle\|Tzeng, Ching-Wei D\|Cannon, Emily E\|Ku, Brandon C\|Howard, J Harrison\|Vickers, Selwyn M\|Heslin, Martin J\|Buchsbaum, Donald J\|Arnoletti, J Pablo
PMID:	17457047

24.
Journal:	Cancer Sci. 2007 Jul;98(7):1099-106. Epub 2007 Apr 23.
Title:	RNA interference-mediated signal transducers and activators of transcription 3 gene silencing inhibits invasion and metastasis of human pancreatic cancer cells.
Author:	Qiu, Zhengjun\|Huang, Chen\|Sun, Jing\|Qiu, Wei\|Zhang, Jufeng\|Li, Huiming\|Jiang, Tao\|Huang, Kejian\|Cao, Jun
PMID:	17459060

25.
Journal:	Cancer Biol Ther. 2007 Aug;6(8):1173-80. Epub 2007 Apr 29.
Title:	Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion.
Author:	Fukasawa, Mitsuharu\|Matsushita, Akira\|Korc, Murray
PMID:	17726369

26.
Journal:	Ann Surg Oncol. 2007 Dec;14(12):3620-8.
Title:	Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells.
Author:	Hering, Justin\|Garrean, Sean\|Dekoj, Thomas R\|Razzak, Anthony\|Saied, Abdul\|Trevino, Jose\|Babcock, Tricia A\|Espat, N Joseph
PMID:	17896154

27.
Journal:	Clin Cancer Res. 2007 Nov 1;13(21):6459-68.
Title:	Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotop
Author:	Lang, Sven A\|Moser, Christian\|Gaumann, Andreas\|Klein, Dagmar\|Glockzin, Gabriel\|Popp, Felix C\|Dahlke, Marc H\|Piso, Pompiliu\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	17975158

28.
Journal:	BMC Cancer. 2008 Feb 6;8:43.
Title:	Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis.
Author:	Pham, Nhu-An\|Schwock, Joerg\|Iakovlev, Vladimir\|Pond, Greg\|Hedley, David W\|Tsao, Ming-Sound
PMID:	18254976

29.
Journal:	Eur J Cancer. 2008 Jul;44(11):1577-86.
Title:	Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis.
Author:	Moser, Christian\|Schachtschneider, Philipp\|Lang, Sven A\|Gaumann, Andreas\|Mori, Akira\|Zimmermann, Johann\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	18445520

30.
Journal:	Cancer Res. 2008 Jun 1;68(11):4221-8.
Title:	Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells.
Author:	Zhao, Shujie\|Venkatasubbarao, Kolaparthi\|Lazor, Jillian W\|Sperry, Jane\|Jin, Changqing\|Cao, Lin\|Freeman, James W
PMID:	18519681

31.
Journal:	Mol Cancer Ther. 2008 Jun;7(6):1543-50.
Title:	STAT3 inhibition in prostate and pancreatic cancer lines by STAT3 binding sequence oligonucleotides: differential activity between 5' and 3' ends.
Author:	Lewis, H Dan\|Winter, Ashley\|Murphy, Thomas F\|Tripathi, Snehlata\|Pandey, Virendra N\|Barton, Beverly E
PMID:	18566225

32.
Journal:	Mol Cancer Ther. 2008 Nov;7(11):3509-18.
Title:	Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes.
Author:	Lang, Sven A\|Schachtschneider, Philipp\|Moser, Christian\|Mori, Akira\|Hackl, Christina\|Gaumann, Andreas\|Batt, David\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	19001434

33.
Journal:	Mol Cancer Res. 2008 Nov;6(11):1755-65.
Title:	Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3.
Author:	Bharadwaj, Uddalak\|Li, Min\|Chen, Changyi\|Yao, Qizhi
PMID:	19010822

34.
Journal:	Zhonghua Wai Ke Za Zhi. 2008 Jul 1;46(13):1010-3.
Title:	[Effect of RNAi-mediated STAT3 gene inhibition on metastasis of human pancreatic cancer cells].
Author:	Gao, Zhen\|Huang, Chen\|Qiu, Zheng-Jun\|Jiang, Tao\|Zhu, Lin\|Cao, Jun\|Zhang, Fang\|Huang, Ke-Jian
PMID:	19035205

35.
Journal:	Int J Cancer. 2009 Jan 15;124(2):280-6.
Title:	Activation of Src and Src-associated signaling pathways in relation to hypoxia in human cancer xenograft models.
Author:	Pham, Nhu-An\|Magalhaes, Joao M M M\|Do, Trevor\|Schwock, Joerg\|Dhani, Neesha\|Cao, Ping-Jiang\|Hill, Richard P\|Hedley, David W
PMID:	18924149

36.
Journal:	Invest New Drugs. 2009 Dec;27(6):491-502.
Title:	The fungal secondary metabolite trichodimerol inhibits TGF-beta dependent cellular effects and tube formation of MDA-MB-231 cells.
Author:	Serwe, Annegret\|Anke, Timm\|Erkel, Gerhard
PMID:	19009233

37.
Journal:	Int J Mol Med. 2009 Jun;23(6):763-9.
Title:	Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	19424602

38.
Journal:	Biochem Biophys Res Commun. 2009 Aug 14;386(1):35-9.
Title:	Endocrine glands-derived vascular endothelial growth factor protects pancreatic cancer cells from apoptosis via upregulation of the myeloid cell leukemia-1 protein.
Author:	Ren, Li-Nan\|Li, Qing-Fang\|Xiao, Feng-Jun\|Yan, Jun\|Yang, Yue-Feng\|Wang, Li-Sheng\|Guo, Xiao-Zhong\|Wang, Hua
PMID:	19523441

39.
Journal:	Cancer Res. 2009 Jul 15;69(14):5876-84.
Title:	Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.
Author:	Thoennissen, Nils H\|Iwanski, Gabriela B\|Doan, Ngan B\|Okamoto, Ryoko\|Lin, Patricia\|Abbassi, Sam\|Song, Jee Hoon\|Yin, Dong\|Toh, Melvin\|Xie, Wei Dong\|Said, Jonathan W\|Koeffler, H Phillip
PMID:	19605406

40.
Journal:	World J Gastroenterol. 2009 Aug 14;15(30):3757-66.
Title:	Lentivirus-mediated shRNA interference targeting STAT3 inhibits human pancreatic cancer cell invasion.
Author:	Yang, Guang\|Huang, Chen\|Cao, Jun\|Huang, Ke-Jian\|Jiang, Tao\|Qiu, Zheng-Jun
PMID:	19673016

41.
Journal:	Cancer Cell Int. 2009 Aug 27;9:24.
Title:	Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells.
Author:	Hutzen, Brian\|Willis, William\|Jones, Sarah\|Cen, Ling\|Deangelis, Stephanie\|Fuh, Beng\|Lin, Jiayuh
PMID:	19712481

42.
Journal:	Int J Oncol. 2009 Oct;35(4):813-21.
Title:	LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells.
Author:	Unno, Jun\|Satoh, Kennichi\|Hirota, Morihisa\|Kanno, Atsushi\|Hamada, Shin\|Ito, Hiromichi\|Masamune, Atsushi\|Tsukamoto, Nobukazu\|Motoi, Fuyuhiko\|Egawa, Shinichi\|Unno, Michiaki\|Horii, Akira\|Shimosegawa, Tooru
PMID:	19724917

43.
Journal:	Int J Oncol. 2009 Oct;35(4):867-72.
Title:	Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas.
Author:	Hutzen, Brian\|Friedman, Lauren\|Sobo, Matthew\|Lin, Li\|Cen, Ling\|De Angelis, Stephanie\|Yamakoshi, Hiroyuki\|Shibata, Hiroyuki\|Iwabuchi, Yoshiharu\|Lin, Jiayuh
PMID:	19724924

44.
Journal:	Mol Ther. 2010 Jan;18(1):188-97.
Title:	G-rich oligonucleotides inhibit HIF-1alpha and HIF-2alpha and block tumor growth.
Author:	Guan, Yongli\|Reddy, Kavitha Ramasamy\|Zhu, Qiqing\|Li, Yifei\|Lee, KangAe\|Weerasinghe, Priya\|Prchal, Josef\|Semenza, Gregg L\|Jing, Naijie
PMID:	19755960

45.
Journal:	J Cancer Res Clin Oncol. 2010 Apr;136(4):603-10.
Title:	Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling.
Author:	Sun, Chunyan\|Zhang, Meixia\|Shan, Xiaolei\|Zhou, Xueying\|Yang, Jiao\|Wang, Yanli\|Li-Ling, Jesse\|Deng, Yihui
PMID:	19816711

46.
Journal:	Biochem Pharmacol. 2010 May 15;79(10):1398-409.
Title:	A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.
Author:	Zhang, Xiaolei\|Yue, Peibin\|Fletcher, Steven\|Zhao, Wei\|Gunning, Patrick T\|Turkson, James
PMID:	20067773

47.
Journal:	J Pharmacol Exp Ther. 2010 May;333(2):373-81.
Title:	Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.
Author:	Jaganathan, Soumya\|Yue, Peibin\|Turkson, James
PMID:	20100905

48.
Journal:	Cancer Invest. 2010 Feb;28(2):166-71.
Title:	Curcumin inhibits constitutive STAT3 phosphorylation in human pancreatic cancer cell lines and downregulation of survivin/BIRC5 gene expression.
Author:	Glienke, W\|Maute, L\|Wicht, J\|Bergmann, L
PMID:	20121547

49.
Journal:	Clin Cancer Res. 2010 Mar 1;16(5):1423-30.
Title:	ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB.
Author:	Zhang, Yuqing\|Bharadwaj, Uddalak\|Logsdon, Craig D\|Chen, Changyi\|Yao, Qizhi\|Li, Min
PMID:	20160059

50.
Journal:	Pancreas. 2010 Aug;39(6):923-9.
Title:	Inhibition of pancreatic cancer cell growth by cucurbitacin B through modulation of signal transducer and activator of transcription 3 signaling.
Author:	Zhang, Meixia\|Sun, Chunyan\|Shan, Xiaolei\|Yang, Xiaolin\|Li-Ling, Jesse\|Deng, Yihui
PMID:	20182390

51.
Journal:	Mol Cancer Ther. 2010 Mar;9(3):742-50.
Title:	Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells.
Author:	Huang, Shengbing\|Sinicrope, Frank A
PMID:	20197401

52.
Journal:	J Exp Clin Cancer Res. 2010 May 19;29:51.
Title:	Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro.
Author:	Huang, Chen\|Yang, Guang\|Jiang, Tao\|Huang, Kejian\|Cao, Jun\|Qiu, Zhengjun
PMID:	20482858

53.
Journal:	Hum Gene Ther. 2010 Dec;21(12):1723-34.
Title:	MicroRNA-20a overexpression inhibited proliferation and metastasis of pancreatic carcinoma cells.
Author:	Yan, Haijiao\|Wu, Jiangxue\|Liu, Wensong\|Zuo, Yufang\|Chen, Shupeng\|Zhang, Shineng\|Zeng, Musheng\|Huang, Wenlin
PMID:	20583868

54.
Journal:	Int J Mol Med. 2010 Aug;26(2):185-91.
Title:	Suppression of cell death by the secretory form of N-terminal ERC/mesothelin.
Author:	Wang, Tegexibaiyin\|Kajino, Kazunori\|Abe, Masaaki\|Tan, Ke\|Maruo, Masumi\|Sun, Guodong\|Hagiwara, Yoshiaki\|Maeda, Masahiro\|Hino, Okio
PMID:	20596597

55.
Journal:	Mol Cancer Ther. 2010 Sep;9(9):2478-87.
Title:	PIM kinase inhibitors downregulate STAT3(Tyr705) phosphorylation.
Author:	Chang, Marisa\|Kanwar, Nisha\|Feng, Eric\|Siu, Allan\|Liu, Xiujie\|Ma, Dawei\|Jongstra, Jan
PMID:	20667852

56.
Journal:	Mol Cancer Ther. 2010 Aug;9(8):2322-32.
Title:	Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis.
Author:	Nagaraj, Nagathihalli S\|Smith, J Joshua\|Revetta, Frank\|Washington, M Kay\|Merchant, Nipun B
PMID:	20682659

57.
Journal:	Cancer Prev Res (Phila). 2010 Nov;3(11):1379-81.
Title:	Breaking the NF-kappaB and STAT3 alliance inhibits inflammation and pancreatic tumorigenesis.
Author:	Surh, Young-Joon\|Bode, Ann M\|Dong, Zigang
PMID:	20978116

58.
Journal:	Genes Cancer. 2010 Aug;1(8):859-67.
Title:	Involvement of interleukin-6 and androgen receptor signaling in pancreatic cancer.
Author:	Okitsu, Kohichiroh\|Kanda, Tatsuo\|Imazeki, Fumio\|Yonemitsu, Yutaka\|Ray, Ratna B\|Chang, Chawnshang\|Yokosuka, Osamu
PMID:	21779469

59.
Journal:	Tumour Biol. 2011 Jun;32(3):493-500.
Title:	Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines.
Author:	Glienke, Wolfgang\|Hausmann, Eva\|Bergmann, Lothar
PMID:	21174186

60.
Journal:	ACS Med Chem Lett. 2011 Jan 13;2(1):79-84.
Title:	Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies.
Author:	Shahani, Vijay M\|Yue, Peibin\|Haftchenary, Sina\|Zhao, Wei\|Lukkarila, Julie L\|Zhang, Xiaolei\|Ball, Daniel\|Nona, Christina\|Gunning, Patrick T\|Turkson, James
PMID:	21243039

61.
Journal:	Ann N Y Acad Sci. 2011 Jan;1215:150-60.
Title:	Chemosensitization of tumors by resveratrol.
Author:	Gupta, Subash C\|Kannappan, Ramaswamy\|Reuter, Simone\|Kim, Ji Hye\|Aggarwal, Bharat B
PMID:	21261654

62.
Journal:	Clin Cancer Res. 2011 Feb 1;17(3):483-93.
Title:	Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth.
Author:	Nagaraj, Nagathihalli S\|Washington, M Kay\|Merchant, Nipun B
PMID:	21266529

63.
Journal:	Pancreas. 2011 Mar;40(2):323-4.
Title:	Targeting STAT3 signaling in pancreatic cancer promotes antiapoptotic gene expression.
Author:	Glienke, Wolfgang\|Hausmann, Eva\|Bergmann, Lothar
PMID:	21311318

64.
Journal:	Int J Oncol. 2011 Jun;38(6):1637-44.
Title:	STAT3-targeting RNA interference inhibits pancreatic cancer angiogenesis in vitro and in vivo.
Author:	Huang, Chen\|Jiang, Tao\|Zhu, Lin\|Liu, Jun\|Cao, Jun\|Huang, Ke-Jian\|Qiu, Zheng-Jun
PMID:	21479358

65.
Journal:	Cancer Cell. 2011 Apr 12;19(4):456-69.
Title:	Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer.
Author:	Lesina, Marina\|Kurkowski, Magdalena U\|Ludes, Katharina\|Rose-John, Stefan\|Treiber, Matthias\|Kloppel, Gunter\|Yoshimura, Akihiko\|Reindl, Wolfgang\|Sipos, Bence\|Akira, Shizuo\|Schmid, Roland M\|Algul, Hana
PMID:	21481788

66.
Journal:	PLoS One. 2011 May 5;6(5):e19605.
Title:	A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.
Author:	Jaganathan, Soumya\|Yue, Peibin\|Paladino, David C\|Bogdanovic, Jelena\|Huo, Qun\|Turkson, James
PMID:	21573184

67.
Journal:	Cancer Prev Res (Phila). 2011 Jul;4(7):1041-51.
Title:	Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer.
Author:	Lashinger, Laura M\|Malone, Lauren M\|Brown, Graham W\|Daniels, Elizabeth A\|Goldberg, Jason A\|Otto, Glen\|Fischer, Susan M\|Hursting, Stephen D
PMID:	21593197

68.
Journal:	Anticancer Res. 2011 Jun;31(6):2029-35.
Title:	LLL12 inhibits endogenous and exogenous interleukin-6-induced STAT3 phosphorylation in human pancreatic cancer cells.
Author:	Liu, Aiguo\|Liu, Yan\|Li, Pui-Kai\|Li, Chenglong\|Lin, Jiayuh
PMID:	21737619

69.
Journal:	Neoplasma. 2011;58(5):396-405.
Title:	The effects and mechanisms of blockage of STAT3 signaling pathway on IL-6 inducing EMT in human pancreatic cancer cells in vitro.
Author:	Huang, C\|Yang, G\|Jiang, T\|Zhu, G\|Li, H\|Qiu, Z
PMID:	21744993

70.
Journal:	World J Gastroenterol. 2011 Jul 7;17(25):2992-3001.
Title:	Down-regulation of STAT3 expression by vector-based small interfering RNA inhibits pancreatic cancer growth.
Author:	Huang, Chen\|Yang, Guang\|Jiang, Tao\|Cao, Jun\|Huang, Ke-Jian\|Qiu, Zheng-Jun
PMID:	21799645

71.
Journal:	PLoS One. 2011;6(10):e25941.
Title:	STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice.
Author:	Li, Hai dong\|Huang, Chen\|Huang, Ke jian\|Wu, Wei dong\|Jiang, Tao\|Cao, Jun\|Feng, Zhen zhong\|Qiu, Zheng jun
PMID:	21991388

72.
Journal:	Oncology. 2011;81(3-4):259-72.
Title:	Molecular pathogenesis of pancreatic cancer and clinical perspectives.
Author:	Matthaios, D\|Zarogoulidis, P\|Balgouranidou, I\|Chatzaki, E\|Kakolyris, S
PMID:	22116519

73.
Journal:	Neoplasma. 2012;59(1):52-61.
Title:	The expression and clinical significance of pSTAT3, VEGF and VEGF-C in pancreatic adenocarcinoma.
Author:	Huang, C\|Huang, R\|Chang, W\|Jiang, T\|Huang, K\|Cao, J\|Sun, X\|Qiu, Z
PMID:	22082308

74.
Journal:	Metab Brain Dis. 2012 Mar;27(1):91-100.
Title:	High level interleukin-6 in the medium of human pancreatic cancer cell culture suppresses production of neurotransmitters by PC12 cell line.
Author:	Li, Rong\|Hou, Jian\|Xu, Qing\|Liu, Qing-Jun\|Shen, Yi-Jun\|Rodin, Gary\|Li, Madeline
PMID:	22109853

75.
Journal:	Pancreas. 2012 Jul;41(5):773-81.
Title:	IL-6 stimulates STAT3 and Pim-1 kinase in pancreatic cancer cell lines.
Author:	Block, Katherine M\|Hanke, Neale T\|Maine, Erin A\|Baker, Amanda F
PMID:	22273698

76.
Journal:	Int J Cancer. 2012 Nov 1;131(9):2175-86.
Title:	Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-kappaB signaling pathways.
Author:	Hafeez, Bilal Bin\|Jamal, Mohammad Sarwar\|Fischer, Joseph W\|Mustafa, Ala\|Verma, Ajit Kumar
PMID:	22322442

77.
Journal:	Cytokine Growth Factor Rev. 2012 Feb-Apr;23(1-2):25-35.
Title:	Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesis.
Author:	Huang, Chen\|Xie, Keping
PMID:	22342309

78.
Journal:	PLoS One. 2012;7(2):e31067.
Title:	EGCG enhances the therapeutic potential of gemcitabine and CP690550 by inhibiting STAT3 signaling pathway in human pancreatic cancer.
Author:	Tang, Su-Ni\|Fu, Junsheng\|Shankar, Sharmila\|Srivastava, Rakesh K
PMID:	22348037

79.
Journal:	J Gastrointest Surg. 2012 Jun;16(6):1136-43.
Title:	Genomic analysis of pterostilbene predicts its antiproliferative effects against pancreatic cancer in vitro and in vivo.
Author:	McCormack, Denise Elizabeth\|Mannal, Patrick\|McDonald, Debbie\|Tighe, Scott\|Hanson, Joshua\|McFadden, David
PMID:	22450950

80.
Journal:	Proc Natl Acad Sci U S A. 2012 May 1;109(18):7031-6.
Title:	The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia.
Author:	Kang, Rui\|Loux, Tara\|Tang, Daolin\|Schapiro, Nicole E\|Vernon, Philip\|Livesey, Kristen M\|Krasinskas, Alyssa\|Lotze, Michael T\|Zeh, Herbert J 3rd
PMID:	22509024

81.
Journal:	Autophagy. 2012 Jun;8(6):989-91.
Title:	AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway.
Author:	Kang, Rui\|Tang, Daolin\|Lotze, Michael T\|Zeh, Herbert J 3rd
PMID:	22722139

82.
Journal:	PLoS One. 2012;7(6):e38625.
Title:	YM155 induces EGFR suppression in pancreatic cancer cells.
Author:	Na, Young-Soon\|Yang, Soo-Jin\|Kim, Seung-Mi\|Jung, Kyung-Ah\|Moon, Jai-Hee\|Shin, Jae-Sik\|Yoon, Dok Hyun\|Hong, Yong Sang\|Ryu, Min-Hee\|Lee, Jae-Lyun\|Lee, Jung Shin\|Kim, Tae Won
PMID:	22723871

83.
Journal:	Cell Mol Life Sci. 2012 Nov;69(22):3863-79.
Title:	CD24 controls Src/STAT3 activity in human tumors.
Author:	Bretz, Niko P\|Salnikov, Alexei V\|Perne, Claudia\|Keller, Sascha\|Wang, Xiaoli\|Mierke, Claudia T\|Fogel, Mina\|Erbe-Hofmann, Natalie\|Schlange, Thomas\|Moldenhauer, Gerhard\|Altevogt, Peter
PMID:	22760497

84.
Journal:	Cancer Cell. 2012 Sep 11;22(3):318-30.
Title:	EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Author:	Navas, Carolina\|Hernandez-Porras, Isabel\|Schuhmacher, Alberto J\|Sibilia, Maria\|Guerra, Carmen\|Barbacid, Mariano
PMID:	22975375

85.
Journal:	J Clin Invest. 2012 Nov;122(11):4118-29.
Title:	Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans.
Author:	Ochi, Atsuo\|Graffeo, Christopher S\|Zambirinis, Constantinos P\|Rehman, Adeel\|Hackman, Michael\|Fallon, Nina\|Barilla, Rocky M\|Henning, Justin R\|Jamal, Mohsin\|Rao, Raghavendra\|Greco, Stephanie\|Deutsch, Michael\|Medina-Zea, Marco V\|Bin Saeed, Usama\|Ego-Osuala,
PMID:	23023703

86.
Journal:	Carcinogenesis. 2012 Dec;33(12):2467-76.
Title:	Transcriptional regulation of the interleukin-11 gene by oncogenic Ras.
Author:	Shin, Soon Young\|Choi, Chan\|Lee, Hong Ghi\|Lim, Yoongho\|Lee, Young Han
PMID:	23027619

87.
Journal:	J Org Chem. 2012 Nov 2;77(21):9659-67.
Title:	Total synthesis and biological activity of the proposed structure of phaeosphaeride A.
Author:	Chatzimpaloglou, Anthoula\|Yavropoulou, Maria P\|Rooij, Karien E\|Biedermann, Ralf\|Mueller, Uwe\|Kaskel, Stefan\|Sarli, Vasiliki
PMID:	23050677

88.
Journal:	PLoS One. 2012;7(10):e46624.
Title:	XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells.
Author:	Liu, Aiguo\|Liu, Yan\|Jin, Zhigang\|Hu, Qun\|Lin, Li\|Jou, David\|Yang, Jing\|Xu, Zhenghu\|Wang, Hong\|Li, Chenglong\|Lin, Jiayuh
PMID:	23056374

89.
Journal:	Front Oncol. 2012 Oct 2;2:137.
Title:	Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration.
Author:	Ishii, Isao\|Harada, Yasuo\|Kasahara, Tadashi
PMID:	23061049

90.
Journal:	PLoS One. 2012;7(10):e47462.
Title:	APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival.
Author:	Cardoso, Angelo A\|Jiang, Yanlin\|Luo, Meihua\|Reed, April M\|Shahda, Safi\|He, Ying\|Maitra, Anirban\|Kelley, Mark R\|Fishel, Melissa L
PMID:	23094050

91.
Journal:	Gut Liver. 2012 Oct;6(4):417-22.
Title:	Role of janus kinase/signal transducers and activators of transcription in the pathogenesis of pancreatitis and pancreatic cancer.
Author:	Yu, Ji Hoon\|Kim, Hyeyoung
PMID:	23170143

92.
Journal:	PLoS One. 2012;7(11):e47520.
Title:	Pan-Bcl-2 inhibitor AT-101 enhances tumor cell killing by EGFR targeted T cells.
Author:	Thakur, Archana\|Lum, Lawrence G\|Schalk, Dana\|Azmi, Asfar\|Banerjee, Sanjeev\|Sarkar, Fazlul H\|Mohommad, Ramzi
PMID:	23185240

93.
Journal:	Molecules. 2012 Dec 11;17(12):14733-47.
Title:	MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway.
Author:	Guo, Rong\|Wang, Yi\|Shi, Wei-Ye\|Liu, Bin\|Hou, Sheng-Qi\|Liu, Li
PMID:	23519249

94.
Journal:	Oncogene. 2013 Mar 14;32(11):1384-95.
Title:	Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha7nAChR-mediated MUC4 upregulation.
Author:	Momi, N\|Ponnusamy, M P\|Kaur, S\|Rachagani, S\|Kunigal, S S\|Chellappan, S\|Ouellette, M M\|Batra, S K
PMID:	22614008

95.
Journal:	Oncogene. 2013 May 23;32(21):2690-5.
Title:	Requirement of NEMO/IKKgamma for effective expansion of KRAS-induced precancerous lesions in the pancreas.
Author:	Maier, H J\|Wagner, M\|Schips, T G\|Salem, H H\|Baumann, B\|Wirth, T
PMID:	22751123

96.
Journal:	Mol Oncol. 2013 Jun;7(3):369-78.
Title:	Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.
Author:	Nam, Sangkil\|Wen, Wei\|Schroeder, Anne\|Herrmann, Andreas\|Yu, Hua\|Cheng, Xinlai\|Merz, Karl-Heinz\|Eisenbrand, Gerhard\|Li, Hongzhi\|Yuan, Yate-Ching\|Jove, Richard
PMID:	23206899

97.
Journal:	Cancer Res. 2013 Feb 1;73(3):1128-41.
Title:	Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses.
Author:	Mitchem, Jonathan B\|Brennan, Donal J\|Knolhoff, Brett L\|Belt, Brian A\|Zhu, Yu\|Sanford, Dominic E\|Belaygorod, Larisa\|Carpenter, Danielle\|Collins, Lynne\|Piwnica-Worms, David\|Hewitt, Stephen\|Udupi, Girish Mallya\|Gallagher, William M\|Wegner, Craig\|West, Brian
PMID:	23221383

98.
Journal:	Mol Cancer Ther. 2013 Mar;12(3):264-73.
Title:	Interaction of the sympathetic nerve with pancreatic cancer cells promotes perineural invasion through the activation of STAT3 signaling.
Author:	Guo, Kun\|Ma, Qingyong\|Li, Junhui\|Wang, Zheng\|Shan, Tao\|Li, Wei\|Xu, Qinhong\|Xie, Keping
PMID:	23288783

99.
Journal:	Eur J Med Chem. 2013 Apr;62:498-507.
Title:	Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy.
Author:	Chen, Haijun\|Yang, Zhengduo\|Ding, Chunyong\|Chu, Lili\|Zhang, Yusong\|Terry, Kristin\|Liu, Huiling\|Shen, Qiang\|Zhou, Jia
PMID:	23416191

100.
Journal:	J Biol Chem. 2013 Apr 26;288(17):11786-94.
Title:	Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation.
Author:	Mills, Lisa D\|Zhang, Yaqing\|Marler, Ronald J\|Herreros-Villanueva, Marta\|Zhang, Lizhi\|Almada, Luciana L\|Couch, Fergus\|Wetmore, Cynthia\|Pasca di Magliano, Marina\|Fernandez-Zapico, Martin E
PMID:	23482563

101.
Journal:	Cancer Res. 2013 May 15;73(10):3007-18.
Title:	Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner.
Author:	Mace, Thomas A\|Ameen, Zeenath\|Collins, Amy\|Wojcik, Sylwia\|Mair, Markus\|Young, Gregory S\|Fuchs, James R\|Eubank, Tim D\|Frankel, Wendy L\|Bekaii-Saab, Tanios\|Bloomston, Mark\|Lesinski, Gregory B
PMID:	23514705

102.
Journal:	PLoS One. 2013 Apr 16;8(4):e61977.
Title:	Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae.
Author:	Aravindan, Sheeja\|Delma, Caroline R\|Thirugnanasambandan, Somasundaram S\|Herman, Terence S\|Aravindan, Natarajan
PMID:	23613993

103.
Journal:	PLoS One. 2013 May 1;8(5):e61532.
Title:	Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice.
Author:	Mackenzie, Gerardo G\|Huang, Liqun\|Alston, Ninche\|Ouyang, Nengtai\|Vrankova, Kvetoslava\|Mattheolabakis, George\|Constantinides, Panayiotis P\|Rigas, Basil
PMID:	23650499

104.
Journal:	Oncol Rep. 2013 Sep;30(3):1223-30.
Title:	Regulation of miR-155 affects pancreatic cancer cell invasiveness and migration by modulating the STAT3 signaling pathway through SOCS1.
Author:	Huang, Chen\|Li, Haidong\|Wu, Weidong\|Jiang, Tao\|Qiu, Zhengjun
PMID:	23817566

105.
Journal:	Toxicol Lett. 2013 Sep 12;222(1):23-35.
Title:	Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer.
Author:	Bao, Guo-Qing\|Shen, Bai-Yong\|Pan, Chun-Peng\|Zhang, Ya-Jing\|Shi, Min-Min\|Peng, Cheng-Hong
PMID:	23845849

106.
Journal:	Cancer Res. 2013 Sep 15;73(18):5682-94.
Title:	Reg3beta deficiency impairs pancreatic tumor growth by skewing macrophage polarization.
Author:	Gironella, Meritxell\|Calvo, Carlos\|Fernandez, Anna\|Closa, Daniel\|Iovanna, Juan L\|Rosello-Catafau, Joan\|Folch-Puy, Emma
PMID:	23867474

107.
Journal:	Br J Cancer. 2013 Oct 1;109(7):1795-804.
Title:	PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cells.
Author:	Chien, W\|Lee, K L\|Ding, L W\|Wuensche, P\|Kato, H\|Doan, N B\|Poellinger, L\|Said, J W\|Koeffler, H P
PMID:	24002598

108.
Journal:	PLoS One. 2013 Aug 28;8(8):e72061.
Title:	Protein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanism.
Author:	Butler, Amanda M\|Scotti Buzhardt, Michele L\|Li, Shuhua\|Smith, Kristin E\|Fields, Alan P\|Murray, Nicole R
PMID:	24015205

109.
Journal:	Mol Cancer. 2013 Sep 11;12(1):104.
Title:	Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer.
Author:	Venkatasubbarao, Kolaparthi\|Peterson, Lindsay\|Zhao, Shujie\|Hill, Ping\|Cao, Lin\|Zhou, Qing\|Nawrocki, Steffan T\|Freeman, James W
PMID:	24025152

110.
Journal:	PLoS One. 2013 Sep 10;8(9):e73803.
Title:	MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreatic cancer through targeting STAT3.
Author:	Zhao, Gang\|Zhang, Jun-gang\|Shi, Ying\|Qin, Qi\|Liu, Yang\|Wang, Bo\|Tian, Kui\|Deng, Shi-chang\|Li, Xiang\|Zhu, Shuai\|Gong, Qiong\|Niu, Yi\|Wang, Chun-you
PMID:	24040078

111.
Journal:	Oncoimmunology. 2013 Jul 1;2(7):e24891.
Title:	Pancreatic cancer-associated stellate cells: A viable target for reducing immunosuppression in the tumor microenvironment.
Author:	Mace, Thomas A\|Bloomston, Mark\|Lesinski, Gregory B
PMID:	24073373

112.
Journal:	Clin Cancer Res. 2013 Dec 15;19(24):6703-15.
Title:	HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.
Author:	Li, Ling\|Tang, Wenhua\|Wu, Xiaoqing\|Karnak, David\|Meng, Xiaojie\|Thompson, Rachel\|Hao, Xinbao\|Li, Yongmin\|Qiao, Xiaotan T\|Lin, Jiayuh\|Fuchs, James\|Simeone, Diane M\|Chen, Zhi-Nan\|Lawrence, Theodore S\|Xu, Liang
PMID:	24132924

113.
Journal:	Neoplasia. 2013 Oct;15(10):1184-95.
Title:	A novel Ras inhibitor (MDC-1016) reduces human pancreatic tumor growth in mice.
Author:	Mackenzie, Gerardo G\|Bartels, Lauren E\|Xie, Gang\|Papayannis, Ioannis\|Alston, Ninche\|Vrankova, Kvetoslava\|Ouyang, Nengtai\|Rigas, Basil
PMID:	24204197

114.
Journal:	J Mol Biochem. 2013 Feb 20;2(1):18-26.
Title:	STAT3 Inhibition Induces Apoptosis in Cancer Cells Independent of STAT1 or STAT2.
Author:	Shodeinde, Adetola\|Ginjupalli, Kalyani\|Lewis, H Dan\|Riaz, Sheraz\|Barton, Beverly E
PMID:	25364701

115.
Journal:	J Gastrointest Cancer. 2014 Mar;45(1):1-11.
Title:	Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?
Author:	O'Sullivan, Katie E\|Reynolds, John V\|O'Hanlon, Ciara\|O'Sullivan, Jacintha N\|Lysaght, Joanne
PMID:	24163144

116.
Journal:	APMIS. 2014 Jun;122(6):476-81.
Title:	Phosphorylation of STAT3 correlates with HER2 status, but not with survival in pancreatic ductal adenocarcinoma.
Author:	Koperek, Oskar\|Aumayr, Klaus\|Schindl, Martin\|Werba, Gregor\|Soleiman, Afschin\|Schoppmann, Sebastian\|Sahora, Klaus\|Birner, Peter
PMID:	24164699

117.
Journal:	Carcinogenesis. 2014 Apr;35(4):859-66.
Title:	Combined inhibition of Notch and JAK/STAT is superior to monotherapies and impairs pancreatic cancer progression.
Author:	Palagani, Vindhya\|Bozko, Przemyslaw\|El Khatib, Mona\|Belahmer, Hanane\|Giese, Nathalia\|Sipos, Bence\|Malek, Nisar P\|Plentz, Ruben R
PMID:	24293409

118.
Journal:	PLoS One. 2014 Jan 3;9(1):e83618.
Title:	Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle.
Author:	Johns, Neil\|Hatakeyama, Shinji\|Stephens, Nathan A\|Degen, Martin\|Degen, Simone\|Frieauff, Wilfried\|Lambert, Christian\|Ross, James A\|Roubenoff, Ronenn\|Glass, David J\|Jacobi, Carsten\|Fearon, Kenneth C H
PMID:	24404136

119.
Journal:	Bioorg Med Chem. 2014 Feb 15;22(4):1496-505.
Title:	A perylene derivative regulates HIF-1alpha and Stat3 signaling pathways.
Author:	Chen, Han\|Guan, Yongli\|Yuan, Gu\|Zhang, Qiang\|Jing, Naijie
PMID:	24485121

120.
Journal:	Cancer Lett. 2014 May 28;347(1):54-64.
Title:	MicroRNA let-7 downregulates STAT3 phosphorylation in pancreatic cancer cells by increasing SOCS3 expression.
Author:	Patel, Kripa\|Kollory, Anita\|Takashima, Asami\|Sarkar, Sibaji\|Faller, Douglas V\|Ghosh, Sajal K
PMID:	24491408

121.
Journal:	PLoS One. 2014 Feb 5;9(2):e87868.
Title:	Antitumor efficacy of alpha-solanine against pancreatic cancer in vitro and in vivo.
Author:	Lv, Chongqing\|Kong, Hongru\|Dong, Guohua\|Liu, Lewei\|Tong, Kun\|Sun, Hongwei\|Chen, Bicheng\|Zhang, Chunwu\|Zhou, Mengtao
PMID:	24505326

122.
Journal:	Cancer Prev Res (Phila). 2014 Apr;7(4):388-97.
Title:	Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment.
Author:	Yue, Wen\|Yang, Chung S\|DiPaola, Robert S\|Tan, Xiang-Lin
PMID:	24520038

123.
Journal:	Clin Cancer Res. 2014 Mar 1;20(5):1259-73.
Title:	Combined targeting of STAT3/NF-kappaB/COX-2/EP4 for effective management of pancreatic cancer.
Author:	Gong, Jingjing\|Xie, Jianping\|Bedolla, Roble\|Rivas, Paul\|Chakravarthy, Divya\|Freeman, James W\|Reddick, Robert\|Kopetz, Scott\|Peterson, Amanda\|Wang, Huamin\|Fischer, Susan M\|Kumar, Addanki P
PMID:	24520096

124.
Journal:	Semin Immunol. 2014 Feb;26(1):80-7.
Title:	Interleukin-6 in inflammatory and malignant diseases of the pancreas.
Author:	Lesina, Marina\|Wormann, Sonja Maria\|Neuhofer, Patrick\|Song, Liang\|Algul, Hana
PMID:	24572992

125.
Journal:	J Cell Physiol. 2014 Oct;229(10):1437-43.
Title:	Pancreatic cancer-induced cachexia is Jak2-dependent in mice.
Author:	Gilabert, Marine\|Calvo, Ezequiel\|Airoldi, Ana\|Hamidi, Tewfik\|Moutardier, Vincent\|Turrini, Olivier\|Iovanna, Juan
PMID:	24648112

126.
Journal:	Cancer Immunol Immunother. 2014 May;63(5):513-28.
Title:	Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer.
Author:	Panni, Roheena Z\|Sanford, Dominic E\|Belt, Brian A\|Mitchem, Jonathan B\|Worley, Lori A\|Goetz, Brian D\|Mukherjee, Pinku\|Wang-Gillam, Andrea\|Link, Daniel C\|Denardo, David G\|Goedegebuure, S Peter\|Linehan, David C
PMID:	24652403

127.
Journal:	Mol Med Rep. 2014 Jun;9(6):2400-4.
Title:	Downregulation of LKB1 suppresses Stat3 activity to promote the proliferation of esophageal carcinoma cells.
Author:	Wang, Yu-Qi\|Dai, Wei-Min\|Chu, Xiang-Yang\|Yang, Bo\|Zhao, Ming\|Sun, Yu'e
PMID:	24676538

128.
Journal:	Cancer Discov. 2014 Jun;4(6):688-701.
Title:	Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.
Author:	Baumgart, Sandra\|Chen, Nai-Ming\|Siveke, Jens T\|Konig, Alexander\|Zhang, Jin-San\|Singh, Shiv K\|Wolf, Elmar\|Bartkuhn, Marek\|Esposito, Irene\|Hessmann, Elisabeth\|Reinecke, Johanna\|Nikorowitsch, Julius\|Brunner, Marius\|Singh, Garima\|Fernandez-Zapico, Martin E\|Sm
PMID:	24694735

129.
Journal:	Exp Cell Res. 2014 Jun 10;324(2):157-71.
Title:	SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.
Author:	Gill, Roop M S\|Michael, Andreas\|Westley, Leah\|Kocher, Hemant M\|Murphy, Joshua I\|Dhoot, Gurtej K
PMID:	24726914

130.
Journal:	Mol Cancer Ther. 2014 Jul;13(7):1758-71.
Title:	Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling.
Author:	Balic, Anamaria\|Sorensen, Morten Draeby\|Trabulo, Sara Maria\|Sainz, Bruno Jr\|Cioffi, Michele\|Vieira, Catarina R\|Miranda-Lorenzo, Irene\|Hidalgo, Manuel\|Kleeff, Joerg\|Erkan, Mert\|Heeschen, Christopher
PMID:	24785258

131.
Journal:	PLoS One. 2014 May 1;9(5):e96060.
Title:	PTK6 promotes cancer migration and invasion in pancreatic cancer cells dependent on ERK signaling.
Author:	Ono, Hiroaki\|Basson, Marc D\|Ito, Hiromichi
PMID:	24788754

132.
Journal:	Oncotarget. 2014 May 15;5(9):2529-41.
Title:	STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth.
Author:	Gong, Jingjing\|Munoz, Amanda R\|Chan, Daniel\|Ghosh, Rita\|Kumar, Addanki P
PMID:	24796733

133.
Journal:	Biochim Biophys Acta. 2014 Aug;1846(1):152-60.
Title:	Molecular mechanisms of oncogene-induced inflammation and inflammation-sustained oncogene activation in gastrointestinal tumors: an under-appreciated symbiotic relationship.
Author:	Dibra, Denada\|Mishra, Lopa\|Li, Shulin
PMID:	24821201

134.
Journal:	J Pathol. 2014 Oct;234(2):214-27.
Title:	Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer.
Author:	Martinez-Bosch, Neus\|Iglesias, Mar\|Munne-Collado, Jessica\|Martinez-Caceres, Carlos\|Moreno, Mireia\|Guerra, Carmen\|Yelamos, Jose\|Navarro, Pilar
PMID:	24889936

135.
Journal:	Eur J Med Chem. 2014 Jul 23;82:195-203.
Title:	Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3).
Author:	Chen, Haijun\|Yang, Zhengduo\|Ding, Chunyong\|Xiong, Ailian\|Wild, Christopher\|Wang, Lili\|Ye, Na\|Cai, Guoshuai\|Flores, Rudolfo M\|Ding, Ye\|Shen, Qiang\|Zhou, Jia
PMID:	24904966

136.
Journal:	Neoplasia. 2014 Jun;16(6):463-70.
Title:	Chronic pancreatitis and systemic inflammatory response syndrome prevent impact of chemotherapy with gemcitabine in a genetically engineered mouse model of pancreatic cancer.
Author:	Knoop, Richard F\|Sparn, Moritz\|Waldmann, Jens\|Plassmeier, Lars\|Bartsch, Detlef K\|Lauth, Matthias\|Hudemann, Christoph\|Fendrich, Volker
PMID:	24953430

137.
Journal:	J Mol Med (Berl). 2014 Dec;92(12):1257-69.
Title:	SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in pancreatic cancer.
Author:	Wang, Jun\|Zhou, Hong\|Han, Yong\|Liu, Xiulan\|Wang, Min\|Wang, Xin\|Yin, Guoxiao\|Li, Xu\|Xiang, Ming
PMID:	24996521

138.
Journal:	Cancer Lett. 2014 Nov 28;354(2):407-16.
Title:	Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells.
Author:	Peng, Meiyu\|Huang, Bingqing\|Zhang, Qi\|Fu, Shuyu\|Wang, Dan\|Cheng, Xixi\|Wu, Xi\|Xue, Zhenyi\|Zhang, Lijuan\|Zhang, Da\|Da, Yurong\|Dai, Yun\|Yang, Qing\|Yao, Zhi\|Qiao, Liang\|Zhang, Rongxin
PMID:	25128650

139.
Journal:	J Clin Invest. 2014 Oct;124(10):4335-50.
Title:	Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization.
Author:	Magrini, Elena\|Villa, Alessandra\|Angiolini, Francesca\|Doni, Andrea\|Mazzarol, Giovanni\|Rudini, Noemi\|Maddaluno, Luigi\|Komuta, Mina\|Topal, Baki\|Prenen, Hans\|Schachner, Melitta\|Confalonieri, Stefano\|Dejana, Elisabetta\|Bianchi, Fabrizio\|Mazzone, Massimiliano\|
PMID:	25157817

140.
Journal:	Oncotarget. 2014 Oct 15;5(19):9150-68.
Title:	Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer.
Author:	Yan, Hong Hua\|Jung, Kyung Hee\|Son, Mi Kwon\|Fang, Zhenghuan\|Kim, Soo Jung\|Ryu, Ye-Lim\|Kim, Juyoung\|Kim, Mi-Hyun\|Hong, Soon-Sun
PMID:	25193856

141.
Journal:	Oncol Rep. 2014 Dec;32(6):2824-30.
Title:	MicroRNA-216a inhibits pancreatic cancer by directly targeting Janus kinase 2.
Author:	Wang, Siliang\|Chen, Xiaodong\|Tang, Meiyue
PMID:	25220761

142.
Journal:	J Natl Cancer Inst. 2014 Oct 18;106(12). pii: dju332.
Title:	Macrophage polarization in pancreatic carcinoma: role of heparanase enzyme.
Author:	Hermano, Esther\|Meirovitz, Amichay\|Meir, Karen\|Nussbaum, Gabriel\|Appelbaum, Limor\|Peretz, Tamar\|Elkin, Michael
PMID:	25326645

143.
Journal:	Br J Pharmacol. 2015 Jan;172(1):50-63.
Title:	Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells.
Author:	Pathania, Divya\|Kuang, Yuting\|Sechi, Mario\|Neamati, Nouri
PMID:	25047070

144.
Journal:	Carcinogenesis. 2015 Jan;36(1):142-50.
Title:	STAT3 induces anoikis resistance, promotes cell invasion and metastatic potential in pancreatic cancer cells.
Author:	Fofaria, Neel M\|Srivastava, Sanjay K
PMID:	25411359

145.
Journal:	Cancer Lett. 2015 Jan 28;356(2 Pt B):962-70.
Title:	MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer.
Author:	Jiang, Jianxin\|Li, Zhu\|Yu, Chao\|Chen, Meiyuan\|Tian, Se\|Sun, Chengyi
PMID:	25444909

146.
Journal:	Mol Cancer Ther. 2015 Feb;14(2):407-18.
Title:	A preclinical evaluation of SKLB261, a multikinase inhibitor of EGFR/Src/VEGFR2, as a therapeutic agent against pancreatic cancer.
Author:	Pan, Youli\|Zheng, Mingwu\|Zhong, Lei\|Yang, Jiao\|Zhou, Shu\|Qin, Ya\|Xiang, Rong\|Chen, Yuzong\|Yang, Sheng-Yong
PMID:	25519702

147.
Journal:	Mol Pharmacol. 2015;87(3):543-60.
Title:	Novel thiosemicarbazones regulate the signal transducer and activator of transcription 3 (STAT3) pathway: inhibition of constitutive and interleukin 6-induced activation by iron depletion.
Author:	Lui, Goldie Y L\|Kovacevic, Zaklina\|V Menezes, Sharleen\|Kalinowski, Danuta S\|Merlot, Angelica M\|Sahni, Sumit\|Richardson, Des R
PMID:	25561562

148.
Journal:	J Cell Physiol. 2015 Sep;230(9):2212-23.
Title:	LB-1 Exerts Antitumor Activity in Pancreatic Cancer by Inhibiting HIF-1alpha and Stat3 Signaling.
Author:	Niu, Fei\|Li, Yan\|Lai, Fang-Fang\|Ni, Lin\|Ji, Ming\|Jin, Jing\|Yang, Han-Ze\|Wang, Chao\|Zhang, Dong-Ming\|Chen, Xiao-Guang
PMID:	25655308

149.
Journal:	Bioorg Med Chem. 2015 Mar 15;23(6):1348-55.
Title:	Design, synthesis and evaluation of XZH-5 analogues as STAT3 inhibitors.
Author:	Daka, Philias\|Liu, Aiguo\|Karunaratne, Chamini\|Csatary, Erika\|Williams, Cameron\|Xiao, Hui\|Lin, Jiayuh\|Xu, Zhenghu\|Page, Richard C\|Wang, Hong
PMID:	25698618

150.
Journal:	Oncotarget. 2015 Apr 10;6(10):7504-21.
Title:	TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis.
Author:	Gore, Jesse\|Craven, Kelly E\|Wilson, Julie L\|Cote, Gregory A\|Cheng, Monica\|Nguyen, Hai V\|Cramer, Harvey M\|Sherman, Stuart\|Korc, Murray
PMID:	25762644

151.
Journal:	Cancer Lett. 2015 Jun 28;362(1):45-60.
Title:	REG3A accelerates pancreatic cancer cell growth under IL-6-associated inflammatory condition: Involvement of a REG3A-JAK2/STAT3 positive feedback loop.
Author:	Liu, Xiulan\|Wang, Jun\|Wang, Hongjie\|Yin, Guoxiao\|Liu, Yang\|Lei, Xiang\|Xiang, Ming
PMID:	25779676

152.
Journal:	Pancreas. 2015 May;44(4):636-47.
Title:	Metformin suppresses pancreatic tumor growth with inhibition of NFkappaB/STAT3 inflammatory signaling.
Author:	Tan, Xiang-Lin\|Bhattacharyya, Kalyan K\|Dutta, Shamit K\|Bamlet, William R\|Rabe, Kari G\|Wang, Enfeng\|Smyrk, Thomas C\|Oberg, Ann L\|Petersen, Gloria M\|Mukhopadhyay, Debabrata
PMID:	25875801

153.
Journal:	Oncotarget. 2015 May 10;6(13):10940-9.
Title:	LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy.
Author:	Zuo, Mingxin\|Li, Chenglong\|Lin, Jiayuh\|Javle, Milind
PMID:	25883212

154.
Journal:	Oncotarget. 2015 Jun 20;6(17):15297-310.
Title:	A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion.
Author:	Butler, Amanda M\|Scotti Buzhardt, Michele L\|Erdogan, Eda\|Li, Shuhua\|Inman, Kristin S\|Fields, Alan P\|Murray, Nicole R
PMID:	25915428

155.
Journal:	Oncotarget. 2015 Jun 30;6(18):16120-34.
Title:	Leptin signaling enhances cell invasion and promotes the metastasis of human pancreatic cancer via increasing MMP-13 production.
Author:	Fan, Yingchao\|Gan, Yu\|Shen, Yuling\|Cai, Xiaojin\|Song, Yanfang\|Zhao, Fangyu\|Yao, Ming\|Gu, Jianren\|Tu, Hong
PMID:	25948792

156.
Journal:	Oncotarget. 2015 Jun 10;6(16):14472-87.
Title:	Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells.
Author:	Zhao, Chengguang\|Xiao, Hui\|Wu, Xiaojuan\|Li, Chenglong\|Liang, Guang\|Yang, Shulin\|Lin, Jiayuh
PMID:	25961376

157.
Journal:	PLoS One. 2015 May 29;10(5):e0127356.
Title:	Prognostic Role of Phospho-STAT3 in Patients with Cancers of the Digestive System: A Systematic Review and Meta-Analysis.
Author:	Li, Mu-xing\|Bi, Xin-yu\|Huang, Zhen\|Zhao, Jian-jun\|Han, Yue\|Li, Zhi-Yu\|Zhang, Ye-fan\|Li, Yuan\|Chen, Xiao\|Hu, Xu-hui\|Zhao, Hong\|Cai, Jian-qiang
PMID:	26024373

158.
Journal:	Cancer Res. 2015 Jun 1;75(11):2305-15.
Title:	Pancreatic Cancer Combination Therapy Using a BH3 Mimetic and a Synthetic Tetracycline.
Author:	Quinn, Bridget A\|Dash, Rupesh\|Sarkar, Siddik\|Azab, Belal\|Bhoopathi, Praveen\|Das, Swadesh K\|Emdad, Luni\|Wei, Jun\|Pellecchia, Maurizio\|Sarkar, Devanand\|Fisher, Paul B
PMID:	26032425

159.
Journal:	Oncotarget. 2015 Aug 28;6(25):21208-24.
Title:	Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.
Author:	Yue, Wen\|Zheng, Xi\|Lin, Yong\|Yang, Chung S\|Xu, Qing\|Carpizo, Darren\|Huang, Huarong\|DiPaola, Robert S\|Tan, Xiang-Lin
PMID:	26056043

160.
Journal:	Dig Dis Sci. 2015 Dec;60(12):3656-68.
Title:	Reg3g Promotes Pancreatic Carcinogenesis in a Murine Model of Chronic Pancreatitis.
Author:	Yin, Guoxiao\|Du, Jiao\|Cao, Hui\|Liu, Xiulan\|Xu, Qianqian\|Xiang, Ming
PMID:	26182900

161.
Journal:	Biomed Pharmacother. 2015 Jul;73:40-7.
Title:	The inhibitory effects of xanthohumol, a prenylated chalcone derived from hops, on cell growth and tumorigenesis in human pancreatic cancer.
Author:	Jiang, Weiliang\|Zhao, Senlin\|Xu, Ling\|Lu, Yingying\|Lu, Zhanjun\|Chen, Congying\|Ni, Jianbo\|Wan, Rong\|Yang, Lijuan
PMID:	26211581

162.
Journal:	Gastroenterology. 2015 Dec;149(7):1932-1943.e9.
Title:	Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
Author:	Nagathihalli, Nagaraj S\|Castellanos, Jason A\|Shi, Chanjuan\|Beesetty, Yugandhar\|Reyzer, Michelle L\|Caprioli, Richard\|Chen, Xi\|Walsh, Alex J\|Skala, Melissa C\|Moses, Harold L\|Merchant, Nipun B
PMID:	26255562

163.
Journal:	Cancer Res. 2015 Nov 15;75(22):4852-62.
Title:	IL17 Functions through the Novel REG3beta-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.
Author:	Loncle, Celine\|Bonjoch, Laia\|Folch-Puy, Emma\|Lopez-Millan, Maria Belen\|Lac, Sophie\|Molejon, Maria Ines\|Chuluyan, Eduardo\|Cordelier, Pierre\|Dubus, Pierre\|Lomberk, Gwen\|Urrutia, Raul\|Closa, Daniel\|Iovanna, Juan L
PMID:	26404002

164.
Journal:	Mol Med Rep. 2015 Nov;12(5):7782-8.
Title:	Cryptotanshinone suppresses the proliferation and induces the apoptosis of pancreatic cancer cells via the STAT3 signaling pathway.
Author:	Ge, Yuqing\|Yang, Bo\|Chen, Zhe\|Cheng, Rubin
PMID:	26459366

165.
Journal:	Oncotarget. 2015 Dec 1;6(38):41146-61.
Title:	Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth.
Author:	Shukla, Surendra K\|Dasgupta, Aneesha\|Mehla, Kamiya\|Gunda, Venugopal\|Vernucci, Enza\|Souchek, Joshua\|Goode, Gennifer\|King, Ryan\|Mishra, Anusha\|Rai, Ibha\|Nagarajan, Sangeetha\|Chaika, Nina V\|Yu, Fang\|Singh, Pankaj K
PMID:	26510913

166.
Journal:	Gastroenterology. 2015 Dec;149(7):1685-8.
Title:	A New Scalpel for the Treatment of Pancreatic Cancer: Targeting Stromal-Derived STAT3 Signaling.
Author:	Cowan, Robert W\|Maitra, Anirban\|Rhim, Andrew D
PMID:	26526714

167.
Journal:	Onco Targets Ther. 2015 Oct 19;8:2989-3001.
Title:	Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial-mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells.
Author:	Huang, Xince\|Dai, Shengjie\|Dai, Juji\|Xiao, Yuwu\|Bai, Yongyu\|Chen, Bicheng\|Zhou, Mengtao
PMID:	26527884

168.
Journal:	Sci Rep. 2015 Nov 4;5:16067.
Title:	Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer.
Author:	Niu, Zheyu\|Wang, Mengyi\|Zhou, Li\|Yao, Lutian\|Liao, Quan\|Zhao, Yupei
PMID:	26530532

169.
Journal:	Oncotarget. 2015 Dec 29;6(42):44509-22.
Title:	Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
Author:	Mace, Thomas A\|Shakya, Reena\|Elnaggar, Omar\|Wilson, Kristin\|Komar, Hannah M\|Yang, Jennifer\|Pitarresi, Jason R\|Young, Gregory S\|Ostrowski, Michael C\|Ludwig, Thomas\|Bekaii-Saab, Tanios\|Bloomston, Mark\|Lesinski, Gregory B
PMID:	26575024

170.
Journal:	PLoS One. 2015 Dec 7;10(12):e0141392.
Title:	Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages.
Author:	Incio, Joao\|Suboj, Priya\|Chin, Shan M\|Vardam-Kaur, Trupti\|Liu, Hao\|Hato, Tai\|Babykutty, Suboj\|Chen, Ivy\|Deshpande, Vikram\|Jain, Rakesh K\|Fukumura, Dai
PMID:	26641266

171.
Journal:	Cancer Lett. 2016 Jan 28;370(2):260-7.
Title:	p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling.
Author:	Tyagi, Nikhil\|Marimuthu, Saravanakumar\|Bhardwaj, Arun\|Deshmukh, Sachin K\|Srivastava, Sanjeev K\|Singh, Ajay P\|McClellan, Steven\|Carter, James E\|Singh, Seema
PMID:	26546043

172.
Journal:	Eur J Cancer. 2016 Jan;52:109-19.
Title:	Targeting the Janus-activated kinase-2-STAT3 signalling pathway in pancreatic cancer using the HSP90 inhibitor ganetespib.
Author:	Nagaraju, Ganji Purnachandra\|Mezina, Anya\|Shaib, Walid L\|Landry, Jerome\|El-Rayes, Bassel F
PMID:	26682870

173.
Journal:	Gene. 2016 Mar 10;578(2):263-73.
Title:	Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Author:	Xu, Qianqian\|Fu, Rong\|Yin, Guoxiao\|Liu, Xiulan\|Liu, Yang\|Xiang, Ming
PMID:	26719042

174.
Journal:	Int J Oncol. 2016 Mar;48(3):908-18.
Title:	Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition.
Author:	Ioannou, Nikolaos\|Seddon, Alan M\|Dalgleish, Angus\|Mackintosh, David\|Solca, Flavio\|Modjtahedi, Helmout
PMID:	26781210

175.
Journal:	Mol Cancer Ther. 2016 Mar;15(3):491-502.
Title:	GSK-3beta Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression.
Author:	Baumgart, Sandra\|Chen, Nai-Ming\|Zhang, Jin-San\|Billadeau, Daniel D\|Gaisina, Irina N\|Kozikowski, Alan P\|Singh, Shiv K\|Fink, Daniel\|Strobel, Philipp\|Klindt, Caroline\|Zhang, Lizhi\|Bamlet, William R\|Koenig, Alexander\|Hessmann, Elisabeth\|Gress, Thomas M\|Ellenr
PMID:	26823495

176.
Journal:	J Exp Clin Cancer Res. 2016 Feb 4;35:27.
Title:	Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis.
Author:	Huang, Li\|Hu, Bin\|Ni, Jianbo\|Wu, Jianghong\|Jiang, Weiliang\|Chen, Congying\|Yang, Lijuan\|Zeng, Yue\|Wan, Rong\|Hu, Guoyong\|Wang, Xingpeng
PMID:	26847351

177.
Journal:	Mol Cancer Ther. 2016 May;15(5):794-805.
Title:	Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics.
Author:	Arpin, Carolyn C\|Mac, Stephen\|Jiang, Yanlin\|Cheng, Huiwen\|Grimard, Michelle\|Page, Brent D G\|Kamocka, Malgorzata M\|Haftchenary, Sina\|Su, Han\|Ball, Daniel P\|Rosa, David A\|Lai, Ping-Shan\|Gomez-Biagi, Rodolfo F\|Ali, Ahmed M\|Rana, Rahul\|Hanenberg, Helmut\|Kerma
PMID:	26873728

178.
Journal:	Oncotarget. 2016 Mar 8;7(10):11708-23.
Title:	Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling.
Author:	Wu, Xiaoqing\|Tang, Wenhua\|Marquez, Rebecca T\|Li, Ke\|Highfill, Chad A\|He, Fengtian\|Lian, Jiqin\|Lin, Jiayuh\|Fuchs, James R\|Ji, Min\|Li, Ling\|Xu, Liang
PMID:	26887043

179.
Journal:	Oncotarget. 2016 Mar 15;7(11):13182-96.
Title:	Ursolic acid inhibits the growth of human pancreatic cancer and enhances the antitumor potential of gemcitabine in an orthotopic mouse model through suppression of the inflammatory microenvironment.
Author:	Prasad, Sahdeo\|Yadav, Vivek R\|Sung, Bokyung\|Gupta, Subash C\|Tyagi, Amit K\|Aggarwal, Bharat B
PMID:	26909608

180.
Journal:	Oncotarget. 2016 Apr 12;7(15):19863-83.
Title:	Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis.
Author:	Wu, Pin\|Wu, Dang\|Zhao, Lufeng\|Huang, Lijian\|Shen, Gang\|Huang, Jian\|Chai, Ying
PMID:	26959884

181.
Journal:	Gastroenterology. 2016 Jul;151(1):180-193.e12.
Title:	Loss of P53 Function Activates JAK2-STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival.
Author:	Wormann, Sonja M\|Song, Liang\|Ai, Jiaoyu\|Diakopoulos, Kalliope N\|Kurkowski, Magdalena U\|Gorgulu, Kivanc\|Ruess, Dietrich\|Campbell, Andrew\|Doglioni, Claudio\|Jodrell, Duncan\|Neesse, Albrecht\|Demir, Ihsan E\|Karpathaki, Angelica-Phaedra\|Barenboim, Maxim\|Hageman
PMID:	27003603

182.
Journal:	Oncogenesis. 2016 Apr 11;5:e217.
Title:	A natural food sweetener with anti-pancreatic cancer properties.
Author:	Liu, C\|Dai, L-H\|Dou, D-Q\|Ma, L-Q\|Sun, Y-X
PMID:	27065453

183.
Journal:	Mol Med Rep. 2016 Jun;13(6):4774-8.
Title:	Src/STAT3 signaling pathways are involved in KAI1-induced downregulation of VEGF-C expression in pancreatic cancer.
Author:	Liu, Xu\|Guo, Xiaozhong\|Li, Hongyu\|Chen, Jiang\|Qi, Xingshun
PMID:	27082851

184.
Journal:	Cancer Lett. 2016 Jul 1;376(2):387-98.
Title:	HIC1 attenuates invasion and metastasis by inhibiting the IL-6/STAT3 signalling pathway in human pancreatic cancer.
Author:	Hu, Bin\|Zhang, Kundong\|Li, Shaobo\|Li, Hao\|Yan, Zhaowen\|Huang, Li\|Wu, Jianghong\|Han, Xiao\|Jiang, Weiliang\|Mulatibieke, Tunike\|Zheng, Lin\|Wan, Rong\|Wang, Xingpeng\|Hu, Guoyong
PMID:	27085461

185.
Journal:	Nat Med. 2016 May;22(5):497-505.
Title:	Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Author:	Laklai, Hanane\|Miroshnikova, Yekaterina A\|Pickup, Michael W\|Collisson, Eric A\|Kim, Grace E\|Barrett, Alex S\|Hill, Ryan C\|Lakins, Johnathon N\|Schlaepfer, David D\|Mouw, Janna K\|LeBleu, Valerie S\|Roy, Nilotpal\|Novitskiy, Sergey V\|Johansen, Julia S\|Poli, Valer
PMID:	27089513

186.
Journal:	World J Gastrointest Oncol. 2016 Apr 15;8(4):380-8.
Title:	Targeting inflammation in pancreatic cancer: Clinical translation.
Author:	Steele, Colin William\|Kaur Gill, Nina Angharad\|Jamieson, Nigel Balfour\|Carter, Christopher Ross
PMID:	27096033

187.
Journal:	Gastroenterology. 2016 Sep;151(3):526-39.
Title:	YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.
Author:	Gruber, Ralph\|Panayiotou, Richard\|Nye, Emma\|Spencer-Dene, Bradley\|Stamp, Gordon\|Behrens, Axel
PMID:	27215660

188.
Journal:	Evid Based Complement Alternat Med. 2016;2016:8680372.
Title:	Ovatodiolide of Anisomeles indica Exerts the Anticancer Potential on Pancreatic Cancer Cell Lines through STAT3 and NF-kappaB Regulation.
Author:	Hsieh, Ya-Ju\|Tseng, Sung-Pin\|Kuo, Yu-Hsuan\|Cheng, Tain-Lu\|Chiang, Chiao-Yu\|Tzeng, Yew-Min\|Tsai, Wan-Chi
PMID:	27242913

189.
Journal:	Sci Rep. 2016 Jun 9;6:27794.
Title:	LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo.
Author:	Huang, Han-Li\|Chao, Min-Wu\|Chen, Chung-Chun\|Cheng, Chun-Chun\|Chen, Mei-Chuan\|Lin, Chao-Feng\|Liou, Jing-Ping\|Teng, Che-Ming\|Pan, Shiow-Lin
PMID:	27278358

190.
Journal:	Tumour Biol. 2016 Sep;37(9):12455-12464.
Title:	Aphanin, a triterpenoid from Amoora rohituka inhibits K-Ras mutant activity and STAT3 in pancreatic carcinoma cells.
Author:	Rabi, Thangaiyan\|Catapano, Carlo V
PMID:	27333990

191.
Journal:	Onco Targets Ther. 2016 Jul 11;9:4225-37.
Title:	Interleukin-32alpha inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells.
Author:	Chen, Jingfeng\|Wang, Silu\|Su, Jiadong\|Chu, Guanyu\|You, Heyi\|Chen, Zongjing\|Sun, Hongwei\|Chen, Bicheng\|Zhou, Mengtao
PMID:	27471397

192.
Journal:	Mol Cancer Res. 2016 Nov;14(11):1147-1158.
Title:	Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow.
Author:	Grunwald, Barbara\|Vandooren, Jennifer\|Gerg, Michael\|Ahomaa, Kaarin\|Hunger, Annique\|Berchtold, Sonja\|Akbareian, Sophia\|Schaten, Susanne\|Knolle, Percy\|Edwards, Dylan R\|Opdenakker, Ghislain\|Kruger, Achim
PMID:	27489361

193.
Journal:	Cancer Res. 2016 Sep 15;76(18):5395-404.
Title:	Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation.
Author:	Xiao, Qian\|Zhou, Donger\|Rucki, Agnieszka A\|Williams, Jamila\|Zhou, Jiaojiao\|Mo, Guanglan\|Murphy, Adrian\|Fujiwara, Kenji\|Kleponis, Jennifer\|Salman, Bulent\|Wolfgang, Christopher L\|Anders, Robert A\|Zheng, Shu\|Jaffee, Elizabeth M\|Zheng, Lei
PMID:	27496707

194.
Journal:	Oncotarget. 2016 Sep 20;7(38):61469-61484.
Title:	Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.
Author:	Yamamoto, Keisuke\|Tateishi, Keisuke\|Kudo, Yotaro\|Hoshikawa, Mayumi\|Tanaka, Mariko\|Nakatsuka, Takuma\|Fujiwara, Hiroaki\|Miyabayashi, Koji\|Takahashi, Ryota\|Tanaka, Yasuo\|Ijichi, Hideaki\|Nakai, Yousuke\|Isayama, Hiroyuki\|Morishita, Yasuyuki\|Aoki, Taku\|Sakamoto
PMID:	27528027

195.
Journal:	Mol Cancer Ther. 2016 Nov;15(11):2722-2732.
Title:	Regulation of HIF1alpha under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.
Author:	Logsdon, Derek P\|Grimard, Michelle\|Luo, Meihua\|Shahda, Safi\|Jiang, Yanlin\|Tong, Yan\|Yu, Zhangsheng\|Zyromski, Nicholas\|Schipani, Ernestina\|Carta, Fabrizio\|Supuran, Claudiu T\|Korc, Murray\|Ivan, Mircea\|Kelley, Mark R\|Fishel, Melissa L
PMID:	27535970

196.
Journal:	Mol Cancer Ther. 2016 Nov;15(11):2609-2619.
Title:	Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy.
Author:	Wu, Xiaojuan\|Cao, Yang\|Xiao, Hui\|Li, Chenglong\|Lin, Jiayuh
PMID:	27535971

197.
Journal:	Sci Rep. 2016 Aug 19;6:31672.
Title:	In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis, and STAT3 and NFkappaB signaling in pancreatic cancer cells.
Author:	Duan, JingJing\|Yue, Wen\|E, JianYu\|Malhotra, Jyoti\|Lu, Shou-En\|Gu, Jun\|Xu, Feng\|Tan, Xiang-Lin
PMID:	27539371

198.
Journal:	Oncotarget. 2016 Sep 20;7(38):62177-62193.
Title:	Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling.
Author:	Xu, Bao-Qing\|Fu, Zhi-Guang\|Meng, Yao\|Wu, Xiao-Qing\|Wu, Bo\|Xu, Liang\|Jiang, Jian-Li\|Li, Ling\|Chen, Zhi-Nan
PMID:	27556697

199.
Journal:	Cancer Lett. 2016 Nov 1;382(1):53-63.
Title:	Gemcitabine treatment promotes pancreatic cancer stemness through the Nox/ROS/NF-kappaB/STAT3 signaling cascade.
Author:	Zhang, Zhengle\|Duan, Qingke\|Zhao, Hengqiang\|Liu, Tao\|Wu, Heshui\|Shen, Qiang\|Wang, Chunyou\|Yin, Tao
PMID:	27576197

200.
Journal:	Oncotarget. 2016 Sep 20;7(38):62305-62311.
Title:	A single nucleotide polymorphism in the 3'-UTR of STAT3 regulates its expression and reduces risk of pancreatic cancer in a Chinese population.
Author:	Zhu, Beibei\|Zhu, Ying\|Lou, Jiao\|Ke, Juntao\|Zhang, Yi\|Li, Jiaoyuan\|Gong, Yajie\|Yang, Yang\|Tian, Jianbo\|Peng, Xiating\|Zou, Danyi\|Zhong, Rong\|Gong, Jing\|Chang, Jiang\|Li, Lu\|Miao, Xiaoping
PMID:	27577070

201.
Journal:	Oncotarget. 2016 Oct 4;7(40):65982-65992.
Title:	Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells.
Author:	Nagathihalli, Nagaraj S\|Castellanos, Jason A\|VanSaun, Michael N\|Dai, Xizi\|Ambrose, Mahogany\|Guo, Qiaozhi\|Xiong, Yanhua\|Merchant, Nipun B
PMID:	27602757

202.
Journal:	J Transl Med. 2016 Sep 29;14(1):282.
Title:	Gemcitabine reduces MDSCs, tregs and TGFbeta-1 while restoring the teff/treg ratio in patients with pancreatic cancer.
Author:	Eriksson, Emma\|Wenthe, Jessica\|Irenaeus, Sandra\|Loskog, Angelica\|Ullenhag, Gustav
PMID:	27687804

203.
Journal:	Int J Oncol. 2016 Dec;49(6):2265-2274.
Title:	STAT3 as a potential therapeutic target in ALDH+ and CD44+/CD24+ stem cell-like pancreatic cancer cells.
Author:	Lin, Li\|Jou, David\|Wang, Yina\|Ma, Haiyan\|Liu, Tianshu\|Fuchs, James\|Li, Pui-Kai\|Lu, Jiagao\|Li, Chenglong\|Lin, Jiayuh
PMID:	27748818

204.
Journal:	J Biol Chem. 2016 Dec 30;291(53):27122-27133.
Title:	Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer.
Author:	Kasiappan, Ravi\|Jutooru, Indira\|Karki, Keshav\|Hedrick, Erik\|Safe, Stephen
PMID:	27875298

205.
Journal:	Mol Carcinog. 2017 Feb;56(2):402-411.
Title:	Downregulation of STAT3/NF-kappaB potentiates gemcitabine activity in pancreatic cancer cells.
Author:	Gong, Jingjing\|Munoz, Amanda R\|Pingali, Subramanya\|Payton-Stewart, Florastina\|Chan, Daniel E\|Freeman, James W\|Ghosh, Rita\|Kumar, Addanki P
PMID:	27208550

206.
Journal:	Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):296-306.
Title:	Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells.
Author:	Wu, Yuan Seng\|Chung, Ivy\|Wong, Won Fen\|Masamune, Atsushi\|Sim, Maw Shin\|Looi, Chung Yeng
PMID:	27750041

207.
Journal:	Cancer Lett. 2017 Mar 28;389:41-48.
Title:	SRI36160 is a specific inhibitor of Wnt/beta-catenin signaling in human pancreatic and colorectal cancer cells.
Author:	Li, Yonghe\|Oliver, Patsy G\|Lu, Wenyan\|Pathak, Vibha\|Sridharan, Sivaram\|Augelli-Szafran, Corinne E\|Buchsbaum, Donald J\|Suto, Mark J
PMID:	28043913

208.
Journal:	Mol Cancer Res. 2017 Apr;15(4):478-488.
Title:	Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer.
Author:	Smigiel, Jacob M\|Parameswaran, Neetha\|Jackson, Mark W
PMID:	28053127

209.
Journal:	Anticancer Drugs. 2017 Apr;28(4):392-400.
Title:	A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells.
Author:	Hu, Yan\|Zhao, Chengguang\|Zheng, Hailun\|Lu, Kongqin\|Shi, Dengjian\|Liu, Zhiguo\|Dai, Xuanxuan\|Zhang, Yi\|Zhang, Xiuhua\|Hu, Wanle\|Liang, Guang
PMID:	28067673

210.
Journal:	Oncol Rep. 2017 Feb;37(2):1189-1195.
Title:	Downregulation of the N-myc downstream regulated gene 1 is related to enhanced proliferation, invasion and migration of pancreatic cancer.
Author:	Cen, Gang\|Zhang, Kundong\|Cao, Jun\|Qiu, Zhengjun
PMID:	28075464

211.
Journal:	PLoS One. 2017 Jan 23;12(1):e0170390.
Title:	The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation.
Author:	Jahny, Elisabeth\|Yang, Hai\|Liu, Bin\|Jahnke, Beatrix\|Lademann, Franziska\|Knosel, Thomas\|Rummele, Petra\|Grutzmann, Robert\|Aust, Daniela E\|Pilarsky, Christian\|Denz, Axel
PMID:	28114355

212.
Journal:	Autophagy. 2017 Apr 3;13(4):703-714.
Title:	MIR506 induces autophagy-related cell death in pancreatic cancer cells by targeting the STAT3 pathway.
Author:	Sun, Longhao\|Hu, Limei\|Cogdell, David\|Lu, Li\|Gao, Chao\|Tian, Weijun\|Zhang, Zhixiang\|Kang, Ya'an\|Fleming, Jason B\|Zhang, Wei
PMID:	28121485

213.
Journal:	Anticancer Res. 2017 Feb;37(2):547-553.
Title:	The Antiproliferative and Colony-suppressive Activities of STAT3 Inhibitors in Human Cancer Cells Is Compromised Under Hypoxic Conditions.
Author:	Tian, Jilai\|Xiao, Hui\|Wu, Ruohan\|Cao, Yang\|Li, Chenglong\|Xu, Ronald\|Pierson, Christopher R\|Finlay, Jonathan L\|Yang, Fang\|Gu, Ning\|Lin, Jiayuh
PMID:	28179300

214.
Journal:	Oncoimmunology. 2016 Nov 2;6(1):e1252013.
Title:	Immunosuppressive CD14(+)HLA-DR(lo/neg) monocytes are elevated in pancreatic cancer and "primed" by tumor-derived exosomes.
Author:	Javeed, Naureen\|Gustafson, Michael P\|Dutta, Shamit K\|Lin, Yi\|Bamlet, William R\|Oberg, Ann L\|Petersen, Gloria M\|Chari, Suresh T\|Dietz, Allan B\|Mukhopadhyay, Debabrata
PMID:	28197368

215.
Journal:	Cancer Lett. 2017 May 28;394:76-87.
Title:	Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer.
Author:	Leal, Ana S\|Williams, Charlotte R\|Royce, Darlene B\|Pioli, Patricia A\|Sporn, Michael B\|Liby, Karen T
PMID:	28254412

216.
Journal:	World J Gastroenterol. 2017 Mar 7;23(9):1594-1601.
Title:	miR-1181 inhibits invasion and proliferation via STAT3 in pancreatic cancer.
Author:	Wang, Jie\|Guo, Xing-Jun\|Ding, You-Ming\|Jiang, Jian-Xin
PMID:	28321160

217.
Journal:	Sci Rep. 2017 Mar 21;7:44908.
Title:	Ultrasound mediated delivery of oxygen and LLL12 loaded stimuli responsive microdroplets for the treatment of hypoxic cancer cells.
Author:	Xu, Jinshun\|Yuan, Shuai\|Tian, Jilai\|Martin, Kyle A\|Song, Jinhua\|Li, Chenglong\|Wang, Zhigang\|Lin, Jiayuh\|Si, Ting\|Xu, Ronald X
PMID:	28322306

218.
Journal:	Cancer Res. 2017 Apr 15;77(8):1868-1879.
Title:	PanIN Neuroendocrine Cells Promote Tumorigenesis via Neuronal Cross-talk.
Author:	Sinha, Smrita\|Fu, Ya-Yuan\|Grimont, Adrien\|Ketcham, Maren\|Lafaro, Kelly\|Saglimbeni, Joseph A\|Askan, Gokce\|Bailey, Jennifer M\|Melchor, Jerry P\|Zhong, Yi\|Joo, Min Geol\|Grbovic-Huezo, Olivera\|Yang, In-Hong\|Basturk, Olca\|Baker, Lindsey\|Park, Young\|Kurtz, Rober
PMID:	28386018

219.
Journal:	Oncotarget. 2017 Jun 27;8(26):42621-42637.
Title:	EGFR-induced phosphorylation of type Igamma phosphatidylinositol phosphate kinase promotes pancreatic cancer progression.
Author:	Chen, Chunhua\|Wang, Xiangling\|Fang, Juemin\|Xue, Junli\|Xiong, Xunhao\|Huang, Yan\|Hu, Jinghua\|Ling, Kun
PMID:	28388589

220.
Journal:	Oncoimmunology. 2017 Feb 10;6(3):e1291106.
Title:	JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer.
Author:	Lu, Chunwan\|Talukder, Asif\|Savage, Natasha M\|Singh, Nagendra\|Liu, Kebin
PMID:	28405527

221.
Journal:	Oncotarget. 2017 Apr 25;8(17):29233-29246.
Title:	OSU-A9 inhibits pancreatic cancer cell lines by modulating p38-JAK-STAT3 signaling.
Author:	Tsai, Wan-Chi\|Bai, Li-Yuan\|Chen, Yi-Jin\|Chu, Po-Chen\|Hsu, Ya-Wen\|Sargeant, Aaron M\|Weng, Jing-Ru
PMID:	28418923

222.
Journal:	Biochem Biophys Res Commun. 2017 Jun 10;487(4):820-826.
Title:	Brusatol inhibits growth and induces apoptosis in pancreatic cancer cells via JNK/p38 MAPK/NF-kappab/Stat3/Bcl-2 signaling pathway.
Author:	Xiang, Yukai\|Ye, Wen\|Huang, Chaohao\|Lou, Bin\|Zhang, Jie\|Yu, Dinglai\|Huang, Xince\|Chen, Bicheng\|Zhou, Mengtao
PMID:	28455228

223.
Journal:	Pancreatology. 2017 Jul - Aug;17(4):635-641.
Title:	Tumour-associated macrophages activate migration and STAT3 in pancreatic ductal adenocarcinoma cells in co-cultures.
Author:	Salmiheimo, Aino\|Mustonen, Harri\|Vainionpaa, Sanna\|Shen, Zhanlong\|Kemppainen, Esko\|Puolakkainen, Pauli\|Seppanen, Hanna
PMID:	28476581

224.
Journal:	Sci Rep. 2017 May 11;7(1):1787.
Title:	Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo.
Author:	Komar, Hannah M\|Serpa, Gregory\|Kerscher, Claire\|Schwoegl, Erin\|Mace, Thomas A\|Jin, Ming\|Yang, Ming-Chen\|Chen, Ching-Shih\|Bloomston, Mark\|Ostrowski, Michael C\|Hart, Phil A\|Conwell, Darwin L\|Lesinski, Gregory B
PMID:	28496202

225.
Journal:	Cancer Lett. 2017 Aug 28;402:213-224.
Title:	BRM/SMARCA2 promotes the proliferation and chemoresistance of pancreatic cancer cells by targeting JAK2/STAT3 signaling.
Author:	Zhang, Zhengkui\|Wang, Feng\|Du, Chong\|Guo, Huahu\|Ma, Ling\|Liu, Xiaoran\|Kornmann, Marko\|Tian, Xiaodong\|Yang, Yinmo
PMID:	28602977

226.
Journal:	Mol Cancer Ther. 2017 Sep;16(9):1729-1738.
Title:	Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma.
Author:	Sahu, Nisebita\|Chan, Emily\|Chu, Felix\|Pham, Thinh\|Koeppen, Hartmut\|Forrest, William\|Merchant, Mark\|Settleman, Jeff
PMID:	28619758

227.
Journal:	Oncol Rep. 2017 Aug;38(2):1075-1082.
Title:	MicroRNA-448 suppresses metastasis of pancreatic ductal adenocarcinoma through targeting JAK1/STAT3 pathway.
Author:	Yu, Dan-Li\|Zhang, Tao\|Wu, Kun\|Li, Yan\|Wang, Juan\|Chen, Jun\|Li, Xiao-Quan\|Peng, Xing-Guo\|Wang, Jia-Ning\|Tan, Li-Guo
PMID:	28677798

228.
Journal:	Oncoimmunology. 2017 Apr 28;6(6):e1321185.
Title:	Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFNgamma signaling.
Author:	Penafuerte, Claudia\|Feldhammer, Matthew\|Mills, John R\|Vinette, Valerie\|Pike, Kelly A\|Hall, Anita\|Migon, Eva\|Karsenty, Gerard\|Pelletier, Jerry\|Zogopoulos, George\|Tremblay, Michel L
PMID:	28680757

229.
Journal:	Oncogenesis. 2017 Jul 10;6(7):e359.
Title:	Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells.
Author:	Huang, H-L\|Wu, H-Y\|Chu, P-C\|Lai, I-L\|Huang, P-H\|Kulp, S K\|Pan, S-L\|Teng, C-M\|Chen, C-S
PMID:	28692035

230.
Journal:	J Cancer. 2017 Jun 2;8(9):1530-1541.
Title:	Pim-3 Regulates Stemness of Pancreatic Cancer Cells via Activating STAT3 Signaling Pathway.
Author:	Li, Ting\|Wang, Zhen\|Hou, Yi-Feng\|Li, Ying-Yi
PMID:	28775772

231.
Journal:	Int J Oncol. 2017 Oct;51(4):1035-1044.
Title:	Phospho-valproic acid inhibits pancreatic cancer growth in mice: enhanced efficacy by its formulation in poly-(L)-lactic acid-poly(ethylene glycol) nanoparticles.
Author:	Mattheolabakis, George\|Wang, Ruixue\|Rigas, Basil\|Mackenzie, Gerardo G
PMID:	28849098

232.
Journal:	Cell Death Dis. 2017 Sep 7;8(9):e3033.
Title:	Acceleration of pancreatic tumorigenesis under immunosuppressive microenvironment induced by Reg3g overexpression.
Author:	Liu, Xiulan\|Zhou, Zhongshi\|Cheng, Qi\|Wang, Hongjie\|Cao, Hui\|Xu, Qianqian\|Tuo, Yali\|Jiang, Li\|Zou, You\|Ren, Hongyu\|Xiang, Ming
PMID:	28880262

233.
Journal:	Onco Targets Ther. 2017 Sep 25;10:4719-4729.
Title:	Quercetin inhibits epithelial-mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial-mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells.
Author:	Yu, Dinglai\|Ye, Tingting\|Xiang, Yukai\|Shi, Zhehao\|Zhang, Jie\|Lou, Bin\|Zhang, Fan\|Chen, Bicheng\|Zhou, Mengtao
PMID:	29026320

234.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Sep;33(9):1228-1233.
Title:	[Interleukin-9 promotes pancreatic cancer cell proliferation and migration via activation of STAT3 pathway].
Author:	Huang, Qiulan\|Lei, Rong'e\|Qin, Qinyi\|Qin, Shanyu\|Jiang, Haixing\|Hu, Bangli
PMID:	29089082

235.
Journal:	Oncotarget. 2017 Jul 22;8(44):76398-76407.
Title:	Suppression of pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer to gemcitabine and 5FU, and inhibits the formation of pancreatic cancer stem like cells.
Author:	Cho, Jae Hee\|Kim, Sun A\|Park, Soo Been\|Kim, Hee Man\|Song, Si Young
PMID:	29100320

236.
Journal:	Oncol Rep. 2017 Dec;38(6):3632-3638.
Title:	Ursodeoxycholic acid suppresses epithelial-mesenchymal transition and cancer stem cell formation by reducing the levels of peroxiredoxin II and reactive oxygen species in pancreatic cancer cells.
Author:	Kim, Yoon Jae\|Jeong, Seok Hoo\|Kim, Eun-Kyung\|Kim, Eui Joo\|Cho, Jae Hee
PMID:	29130098

237.
Journal:	Oncotarget. 2017 Aug 3;8(49):85378-85391.
Title:	Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth.
Author:	Messaggio, Fanuel\|Mendonsa, Alisha M\|Castellanos, Jason\|Nagathihalli, Nagaraj S\|Gorden, Lee\|Merchant, Nipun B\|VanSaun, Michael N
PMID:	29156726

238.
Journal:	Oncotarget. 2017 Sep 22;8(59):99693-99706.
Title:	Apolipoprotein A-I mimetic peptide 4F suppresses tumor-associated macrophages and pancreatic cancer progression.
Author:	Peng, Meiyu\|Zhang, Qi\|Cheng, Yingnan\|Fu, Shuyu\|Yang, Huipeng\|Guo, Xiangdong\|Zhang, Jieyou\|Wang, Lina\|Zhang, Lijuan\|Xue, Zhenyi\|Li, Yan\|Da, Yurong\|Yao, Zhi\|Qiao, Liang\|Zhang, Rongxin
PMID:	29245934

239.
Journal:	Onco Targets Ther. 2017 Dec 5;10:5783-5794.
Title:	CircRNA_100782 regulates pancreatic carcinoma proliferation through the IL6-STAT3 pathway.
Author:	Chen, Genwen\|Shi, Yanting\|Zhang, Yu\|Sun, Jianyong
PMID:	29255366

240.
Journal:	Oncotarget. 2017 Oct 9;8(61):103167-103181.
Title:	Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activities by suppressing EGFR, PI3K/Akt/mTOR, STAT3 and ERK signaling.
Author:	Zhou, Jingkai\|Zhao, Tiangang\|Ma, Linfeng\|Liang, Min\|Guo, Ying-Jie\|Zhao, Li-Mei
PMID:	29262554

241.
Journal:	Oncotarget. 2016 Jul 1;8(69):113295-113302.
Title:	TLR signaling inhibitor, phenylmethimazole, in combination with tamoxifen inhibits human breast cancer cell viability and migration.
Author:	Schwartz, Anthony L\|Dickerson, Eric\|Dagia, Nilesh\|Malgor, Ramiro\|McCall, Kelly D
PMID:	29371911

242.
Journal:	Cent Eur J Immunol. 2017;42(4):377-382.
Title:	Disorders noticed during development of pancreatic cancer: potential opportunities for early and effective diagnostics and therapy.
Author:	Balan, Barbara Joanna\|Zygmanowska, Ewa\|Radomska-Lesniewska, Dorota Magdalena
PMID:	29472816

243.
Journal:	Gastroenterology. 2018 Apr;154(5):1494-1508.e13.
Title:	Kruppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.
Author:	He, Ping\|Yang, Jong Won\|Yang, Vincent W\|Bialkowska, Agnieszka B
PMID:	29248441

244.
Journal:	Cancer Res. 2018 Feb 15;78(4):909-921.
Title:	LIF Drives Neural Remodeling in Pancreatic Cancer and Offers a New Candidate Biomarker.
Author:	Bressy, Christian\|Lac, Sophie\|Nigri, Jeremy\|Leca, Julie\|Roques, Julie\|Lavaut, Marie-Noelle\|Secq, Veronique\|Guillaumond, Fabienne\|Bui, Thi-Thien\|Pietrasz, Daniel\|Granjeaud, Samuel\|Bachet, Jean-Baptiste\|Ouaissi, Mehdi\|Iovanna, Juan\|Vasseur, Sophie\|Tomasini,
PMID:	29269518

245.
Journal:	Mol Med Rep. 2018 Mar;17(3):3681-3689.
Title:	Luteolin inhibits pancreatitisinduced acinarductal metaplasia, proliferation and epithelialmesenchymal transition of acinar cells.
Author:	Huang, Xince\|Bhugul, Pravin Avinash\|Fan, Gang\|Ye, Tingting\|Huang, Shihao\|Dai, Shengjie\|Chen, Bicheng\|Zhou, Mengtao
PMID:	29286098

246.
Journal:	Oncoimmunology. 2017 Nov 1;7(2):e1388485.
Title:	Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition.
Author:	Siddiqui, Imran\|Erreni, Marco\|Kamal, Mohammad Azhar\|Porta, Chiara\|Marchesi, Federica\|Pesce, Samantha\|Pasqualini, Fabio\|Schiarea, Silvia\|Chiabrando, Chiara\|Mantovani, Alberto\|Allavena, Paola
PMID:	29308316

247.
Journal:	Cancer Lett. 2018 Apr 1;418:167-175.
Title:	MUC16 C terminal-induced secretion of tumor-derived IL-6 contributes to tumor-associated Treg enrichment in pancreatic cancer.
Author:	Fan, Kun\|Yang, Chao\|Fan, Zhiyao\|Huang, Qiuyi\|Zhang, Yiyin\|Cheng, He\|Jin, Kaizhou\|Lu, Yu\|Wang, Zhengshi\|Luo, Guopei\|Yu, Xianjun\|Liu, Chen
PMID:	29337110

248.
Journal:	Oncol Rep. 2018 Apr;39(4):1892-1900.
Title:	Tyrphostin B42 attenuates trichostatin A-mediated resistance in pancreatic cancer cells by antagonizing IL-6/JAK2/STAT3 signaling.
Author:	Zhang, Xing\|Lu, Hong\|Hong, Weilong\|Liu, Leping\|Wang, Silu\|Zhou, Mengtao\|Chen, Bicheng\|Bai, Yongheng
PMID:	29393444

249.
Journal:	Mol Med Rep. 2018 Apr;17(4):5440-5448.
Title:	Ethyl acetate extract from Inula helenium L. inhibits the proliferation of pancreatic cancer cells by regulating the STAT3/AKT pathway.
Author:	Zhang, Bo\|Zeng, Jianmei\|Yan, Youyou\|Yang, Bo\|Huang, Mincong\|Wang, Linling\|Zhang, Qi\|Lin, Nengming
PMID:	29393456

250.
Journal:	Biochem Biophys Res Commun. 2018 Mar 18;497(4):963-970.
Title:	MiR-7-5p functions as a tumor suppressor by targeting SOX18 in pancreatic ductal adenocarcinoma.
Author:	Zhu, Weihua\|Wang, Yazhou\|Zhang, Dafang\|Yu, Xin\|Leng, Xisheng
PMID:	29408481

251.
Journal:	Phytomedicine. 2018 Jan 15;39:10-16.
Title:	Genistein induced anticancer effects on pancreatic cancer cell lines involves mitochondrial apoptosis, G0/G1cell cycle arrest and regulation of STAT3 signalling pathway.
Author:	Bi, Yi-Liang\|Min, Min\|Shen, Wei\|Liu, Yan
PMID:	29433670

252.
Journal:	Pancreatology. 2018 Apr;18(3):328-333.
Title:	Celecoxib suppresses proliferation and metastasis of pancreatic cancer cells by down-regulating STAT3 / NF-kB and L1CAM activities.
Author:	Zuo, Chaohui\|Hong, Yuan\|Qiu, Xiaoxin\|Yang, Darong\|Liu, Nianli\|Sheng, Xinyi\|Zhou, Kunyan\|Tang, Bo\|Xiong, Shuhan\|Ma, Min\|Liu, Zhuo
PMID:	29525378

253.
Journal:	Cancer Res. 2018 Jun 15;78(12):3293-3305.
Title:	IL22RA1/STAT3 Signaling Promotes Stemness and Tumorigenicity in Pancreatic Cancer.
Author:	He, Weizhi\|Wu, Jinghua\|Shi, Juanjuan\|Huo, Yan-Miao\|Dai, Wentao\|Geng, Jing\|Lu, Ping\|Yang, Min-Wei\|Fang, Yuan\|Wang, Wei\|Zhang, Zhi-Gang\|Habtezion, Aida\|Sun, Yong-Wei\|Xue, Jing
PMID:	29572224

254.
Journal:	Cancer Lett. 2018 Jul 10;426:25-36.
Title:	A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer.
Author:	Fang, Zhenghuan\|Han, Boreum\|Jung, Kyung Hee\|Lee, Ju-Hyeon\|El-Damasy, Ashraf Kareem\|Gadhe, Changdev G\|Kim, Soo Jung\|Yan, Hong Hua\|Park, Jung Hee\|Lee, Ji Eun\|Kang, Yeo Wool\|Pae, Ae Nim\|Keum, Gyochang\|Hong, Soon-Sun
PMID:	29605512

255.
Journal:	Cancer Manag Res. 2018 Mar 23;10:565-581.
Title:	L61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway.
Author:	Bai, Encheng\|Yang, Lehe\|Xiang, Youqun\|Hu, Wanle\|Li, Caleb\|Lin, Jiayuh\|Dai, Xuanxuan\|Liang, Guang\|Jin, Rong\|Zhao, Chengguang
PMID:	29606890

256.
Journal:	Integr Cancer Ther. 2018 Sep;17(3):707-716.
Title:	TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.
Author:	Wang, Feng-Jiao\|Wang, Peng\|Chen, Lian-Yu\|Geng, Ya-Wen\|Chen, Hao\|Meng, Zhi-Qiang\|Liu, Lu-Ming\|Chen, Zhen
PMID:	29681184

257.
Journal:	Mol Carcinog. 2018 Sep;57(9):1130-1143.
Title:	A novel tricarbonylmethane agent (CMC2.24) reduces human pancreatic tumor growth in mice by targeting Ras.
Author:	Mallangada, Naveen A\|Vargas, Joselin M\|Thomas, Swaroopa\|DiGiovanni, Matthew G\|Vaeth, Brandon M\|Nemesure, Matthew D\|Wang, Ruixue\|LaComb, Joseph F\|Williams, Jennie L\|Golub, Lorne M\|Johnson, Francis\|Mackenzie, Gerardo G
PMID:	29683208

258.
Journal:	Eur Rev Med Pharmacol Sci. 2018 Apr;22(7):1914-1921.
Title:	MiR-221 inhibits proliferation of pancreatic cancer cells via down regulation of SOCS3.
Author:	Xie, J\|Wen, J-T\|Xue, X-J\|Zhang, K-P\|Wang, X-Z\|Cheng, H-H
PMID:	29687843

259.
Journal:	Curr Cancer Drug Targets. 2018 Apr 30. pii: CCDT-EPUB-90071.
Title:	Blocking IL-6/GP130 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity in human pancreatic cancer cells.
Author:	Chen, Xiang\|Tian, Jilai\|Su, Gloria H\|Lin, Jiayuh
PMID:	29714141

260.
Journal:	Mol Oncol. 2018 Jun;12(7):1203-1215.
Title:	Matrine suppresses KRAS-driven pancreatic cancer growth by inhibiting autophagy-mediated energy metabolism.
Author:	Cho, Young-Ra\|Lee, Ji Hyeon\|Kim, Ji Hye\|Lee, So-Yeon\|Yoo, Suna\|Jung, Min-Kyo\|Kim, Su Jung\|Yoo, Hyun Ju\|Pack, Chang-Gi\|Rho, Jin Kyung\|Son, Jaekyoung
PMID:	29791786

261.
Journal:	J Biol Chem. 2018 Jul 13;293(28):11143-11153.
Title:	Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42.
Author:	Razidlo, Gina L\|Burton, Kevin M\|McNiven, Mark A
PMID:	29853638

262.
Journal:	Mol Ther Nucleic Acids. 2018 Jun 1;11:142-158.
Title:	miR-1266 Contributes to Pancreatic Cancer Progression and Chemoresistance by the STAT3 and NF-kappaB Signaling Pathways.
Author:	Zhang, Xin\|Ren, Dong\|Wu, Xianqiu\|Lin, Xi\|Ye, Liping\|Lin, Chuyong\|Wu, Shu\|Zhu, Jinrong\|Peng, Xinsheng\|Song, Libing
PMID:	29858050

263.
Journal:	J Cell Physiol. 2018 Jun 19.
Title:	EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis.
Author:	Hong, Guoju\|Kuek, Vincent\|Shi, Jiaxi\|Zhou, Lin\|Han, Xiaorui\|He, Wei\|Tickner, Jennifer\|Qiu, Heng\|Wei, Qiushi\|Xu, Jiake
PMID:	29923200

264.
Journal:	Cell Physiol Biochem. 2018;47(5):1751-1768.
Title:	Melatonin Synergizes with Sorafenib to Suppress Pancreatic Cancer via Melatonin Receptor and PDGFR-beta/STAT3 Pathway.
Author:	Fang, Zhenghuan\|Jung, Kyung Hee\|Yan, Hong Hua\|Kim, Soo-Jung\|Rumman, Marufa\|Park, Jung Hee\|Han, Boreum\|Lee, Ji Eun\|Kang, Yeo Wool\|Lim, Joo Han\|Hong, Soon Sun
PMID:	29953970

265.
Journal:	Cancers (Basel). 2018 Jul 31;10(8). pii: cancers10080254.
Title:	TGF-betaRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727.
Author:	Drubay, Vincent\|Skrypek, Nicolas\|Cordiez, Lucie\|Vasseur, Romain\|Schulz, Celine\|Boukrout, Nihad\|Duchene, Belinda\|Coppin, Lucie\|Van Seuningen, Isabelle\|Jonckheere, Nicolas
PMID:	30065235

266.
Journal:	J Cell Physiol. 2018 Aug 4.
Title:	Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor kappaB and STAT3 in vitro and in vivo.
Author:	Song, Yanlin\|Gao, Lei\|Tang, Zhongyuan\|Li, Hailong\|Sun, Bin\|Chu, Peng\|Qaed, Eskandar\|Ma, Xiaodong\|Peng, Jinyong\|Wang, Shisheng\|Hu, Min\|Tang, Zeyao
PMID:	30078206

267.
Journal:	Theranostics. 2018 Jun 13;8(14):3824-3840.
Title:	Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine.
Author:	Lankadasari, Manendra Babu\|Aparna, Jayasekharan S\|Mohammed, Sabira\|James, Shirley\|Aoki, Kazunori\|Binu, Valsalakumari S\|Nair, Sindhu\|Harikumar, Kuzhuvelil B
PMID:	30083262

268.
Journal:	Mol Med Rep. 2018 Oct;18(4):3769-3779.
Title:	EGFR may participate in immune evasion through regulation of B7H5 expression in nonsmall cell lung carcinoma.
Author:	Dong, Zhaohui\|Zhang, Lanying\|Xu, Wei\|Zhang, Gensheng
PMID:	30106102

269.
Journal:	Genes Dev. 2018 Sep 1;32(17-18):1175-1187.
Title:	STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis.
Author:	D'Amico, Stephen\|Shi, Jiaqi\|Martin, Benjamin L\|Crawford, Howard C\|Petrenko, Oleksi\|Reich, Nancy C
PMID:	30135074

270.
Journal:	Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0634.
Title:	Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.
Author:	Nagathihalli, Nagaraj S\|Castellanos, Jason\|Lamichhane, Purushottam\|Messaggio, Fanuel\|Shi, Chanjuan\|Dai, Xizi\|Rai, Priyamvada\|Chen, Xi\|VanSaun, Michael N\|Merchant, Nipun B
PMID:	30154150

271.
Journal:	Oncogene. 2018 Aug 31. pii: 10.1038/s41388-018-0458-y.
Title:	L1CAM induces perineural invasion of pancreas cancer cells by upregulation of metalloproteinase expression.
Author:	Na'ara, Shorook\|Amit, Moran\|Gil, Ziv
PMID:	30171263

272.
Journal:	Med Sci Monit. 2018 Oct 1;24:6975-6983.
Title:	Mahanimbine Exerts Anticancer Effects on Human Pancreatic Cancer Cells by Triggering Cell Cycle Arrest, Apoptosis, and Modulation of AKT/Mammalian Target of Rapamycin (mTOR) and Signal Transducer and Activator of Transcription 3 (STAT3) Signalling Pathway
Author:	Pei, Chenlin\|He, Qun\|Liang, Shuai\|Gong, Xuejun
PMID:	30273298

273.
Journal:	J Cell Physiol. 2018 Oct 14.
Title:	Resistin effects on pancreatic cancer progression and chemoresistance are mediated through its receptors CAP1 and TLR4.
Author:	Zhang, Min\|Yan, Li\|Wang, Gui-Jie\|Jin, Ronghui
PMID:	30317640

274.
Journal:	Int J Mol Sci. 2018 Oct 12;19(10). pii: ijms19103127.
Title:	Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism.
Author:	Kim, Young-Seon\|Lee, Yoon-Mi\|Oh, Taek-In\|Shin, Dong Hoon\|Kim, Geon-Hee\|Kan, Sang-Yeon\|Kang, Hyeji\|Kim, Ji Hyung\|Kim, Byeong Mo\|Yim, Woo Jong\|Lim, Ji-Hong
PMID:	30321984