Primary Site >> Liver Cancer
Gene >> STAT3
| 1. | |||||||||||
| Journal: | J Immunol. 1996 Jul 1;157(1):284-90. | ||||||||||
| Title: | Complex of the soluble IL-11 receptor and IL-11 acts as IL-6-type cytokine in hepatic and nonhepatic cells. | ||||||||||
| Author: | Baumann, H|Wang, Y|Morella, K K|Lai, C F|Dams, H|Hilton, D J|Hawley, R G|Mackiewicz, A | ||||||||||
| PMID: | 8683127 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 1998 Sep 25;273(39):25510-5. | ||||||||||
| Title: | HBx protein of hepatitis B virus activates Jak1-STAT signaling. | ||||||||||
| Author: | Lee, Y H|Yun, Y | ||||||||||
| PMID: | 9738022 | ||||||||||
| 3. | |||||||||||
| Journal: | J Immunol. 1999 Dec 15;163(12):6651-8. | ||||||||||
| Title: | Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130. | ||||||||||
| Author: | Hermanns, H M|Radtke, S|Haan, C|Schmitz-Van de Leur, H|Tavernier, J|Heinrich, P C|Behrmann, I | ||||||||||
| PMID: | 10586060 | ||||||||||
| 4. | |||||||||||
| Journal: | Hunan Yi Ke Da Xue Xue Bao. 2001 Feb 28;26(1):17-9. | ||||||||||
| Title: | [Effects of Stat3 phosphorylation and expression of c-fos and c-jun proteins on hepatocarcinogenesis]. | ||||||||||
| Author: | Feng, D Y|Zheng, H|Jiang, H Y | ||||||||||
| PMID: | 12536605 | ||||||||||
| 5. | |||||||||||
| Journal: | J Exp Med. 2002 Sep 2;196(5):641-53. | ||||||||||
| Title: | Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation. | ||||||||||
| Author: | Yoshida, Takafumi|Hanada, Toshikatsu|Tokuhisa, Takeshi|Kosai, Ken-ichiro|Sata, Michio|Kohara, Michinori|Yoshimura, Akihiko | ||||||||||
| PMID: | 12208879 | ||||||||||
| 6. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1016-21. | ||||||||||
| Title: | Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2. | ||||||||||
| Author: | Leung, K C|Doyle, N|Ballesteros, M|Sjogren, K|Watts, C K W|Low, T H|Leong, G M|Ross, R J M|Ho, K K Y | ||||||||||
| PMID: | 12552091 | ||||||||||
| 7. | |||||||||||
| Journal: | Hepatology. 2003 Aug;38(2):314-25. | ||||||||||
| Title: | A common set of immediate-early response genes in liver regeneration and hyperplasia. | ||||||||||
| Author: | Locker, Joseph|Tian, Jianmin|Carver, Robert|Concas, Danilo|Cossu, Costanza|Ledda-Columbano, Giovanna M|Columbano, Amedeo | ||||||||||
| PMID: | 12883475 | ||||||||||
| 8. | |||||||||||
| Journal: | FEBS Lett. 2003 Dec 18;555(3):528-32. | ||||||||||
| Title: | Expression of hepatitis C virus non-structural 5A protein in the liver of transgenic mice. | ||||||||||
| Author: | Majumder, Mainak|Steele, Robert|Ghosh, Asish K|Zhou, Xiao Yan|Thornburg, Larry|Ray, Ranjit|Phillips, Nancy J|Ray, Ratna B | ||||||||||
| PMID: | 14675768 | ||||||||||
| 9. | |||||||||||
| Journal: | Clin Cancer Res. 2004 Feb 1;10(3):1130-40. | ||||||||||
| Title: | Effects of acyclic retinoid on growth, cell cycle control, epidermal growth factor receptor signaling, and gene expression in human squamous cell carcinoma cells. | ||||||||||
| Author: | Shimizu, Masahito|Suzui, Masumi|Deguchi, Atsuko|Lim, Jin T E|Weinstein, I Bernard | ||||||||||
| PMID: | 14871993 | ||||||||||
| 10. | |||||||||||
| Journal: | Virology. 2004 Apr 25;322(1):51-60. | ||||||||||
| Title: | Hepatitis C virus NS5A mediated STAT3 activation requires co-operation of Jak1 kinase. | ||||||||||
| Author: | Sarcar, Bhaswati|Ghosh, Asish K|Steele, Robert|Ray, Ranjit|Ray, Ratna B | ||||||||||
| PMID: | 15063116 | ||||||||||
| 11. | |||||||||||
| Journal: | Hepatology. 2004 May;39(5):1332-42. | ||||||||||
| Title: | Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. | ||||||||||
| Author: | Radaeva, Svetlana|Sun, Rui|Pan, Hong-Na|Hong, Feng|Gao, Bin | ||||||||||
| PMID: | 15122762 | ||||||||||
| 12. | |||||||||||
| Journal: | Br J Cancer. 2004 Oct 4;91(7):1335-41. | ||||||||||
| Title: | Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line. | ||||||||||
| Author: | To, K F|Chan, M W Y|Leung, W K|Ng, E K W|Yu, J|Bai, A H C|Lo, A W I|Chu, S H|Tong, J H M|Lo, K W|Sung, J J Y|Chan, F K L | ||||||||||
| PMID: | 15354212 | ||||||||||
| 13. | |||||||||||
| Journal: | J Biol Chem. 2005 Feb 25;280(8):6409-15. | ||||||||||
| Title: | Des-gamma-carboxy prothrombin is a potential autologous growth factor for hepatocellular carcinoma. | ||||||||||
| Author: | Suzuki, Mayumi|Shiraha, Hidenori|Fujikawa, Tatsuya|Takaoka, Nobuyuki|Ueda, Naoki|Nakanishi, Yutaka|Koike, Kazuko|Takaki, Akinobu|Shiratori, Yasushi | ||||||||||
| PMID: | 15582995 | ||||||||||
| 14. | |||||||||||
| Journal: | Liver Int. 2005 Apr;25(2):445-57. | ||||||||||
| Title: | Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma. | ||||||||||
| Author: | Moran, Diarmuid M|Mayes, Nicholas|Koniaris, Leonidas G|Cahill, Paul A|McKillop, Iain H | ||||||||||
| PMID: | 15780071 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncogene. 2005 Sep 22;24(42):6406-17. | ||||||||||
| Title: | Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. | ||||||||||
| Author: | Niwa, Yasuharu|Kanda, Hiroaki|Shikauchi, Yuko|Saiura, Akio|Matsubara, Kenichi|Kitagawa, Tomoyuki|Yamamoto, Junji|Kubo, Takahiko|Yoshikawa, Hirohide | ||||||||||
| PMID: | 16007195 | ||||||||||
| 16. | |||||||||||
| Journal: | Gastroenterology. 2005 Jul;129(1):285-302. | ||||||||||
| Title: | Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver. | ||||||||||
| Author: | Tan, Xinping|Apte, Udayan|Micsenyi, Amanda|Kotsagrelos, Emorphia|Luo, Jian-Hua|Ranganathan, Sarangarajan|Monga, Dulabh K|Bell, Aaron|Michalopoulos, George K|Monga, Satdarshan P S | ||||||||||
| PMID: | 16012954 | ||||||||||
| 17. | |||||||||||
| Journal: | Gastroenterology. 2005 Nov;129(5):1616-32. | ||||||||||
| Title: | STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen. | ||||||||||
| Author: | Ray, Sutapa|Boldogh, Istvan|Brasier, Allan R | ||||||||||
| PMID: | 16285960 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncogene. 2006 Apr 20;25(17):2520-30. | ||||||||||
| Title: | Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production. | ||||||||||
| Author: | Ogata, H|Chinen, T|Yoshida, T|Kinjyo, I|Takaesu, G|Shiraishi, H|Iida, M|Kobayashi, T|Yoshimura, A | ||||||||||
| PMID: | 16474852 | ||||||||||
| 19. | |||||||||||
| Journal: | Ai Zheng. 2006 Mar;25(3):269-74. | ||||||||||
| Title: | [Effects of STAT3 antisense oligodeoxynucleotides on apoptosis and proliferation of mouse melanoma cell line B16]. | ||||||||||
| Author: | Tang, Gu-Sheng|Cai, Jian-Ming|Ni, Jin|Xiang, Ying-Song|Cui, Jian-Guo|Zhu, Dan|Dong, Jun-Rui | ||||||||||
| PMID: | 16536977 | ||||||||||
| 20. | |||||||||||
| Journal: | Virology. 2006 Jun 5;349(2):347-58. | ||||||||||
| Title: | Microarray analyses and molecular profiling of Stat3 signaling pathway induced by hepatitis C virus core protein in human hepatocytes. | ||||||||||
| Author: | Basu, Arnab|Meyer, Keith|Lai, Keith K|Saito, Kousuke|Di Bisceglie, Adrian M|Grosso, Leonard E|Ray, Ratna B|Ray, Ranjit | ||||||||||
| PMID: | 16545852 | ||||||||||
| 21. | |||||||||||
| Journal: | Biochem J. 2006 Sep 15;398(3):577-83. | ||||||||||
| Title: | Functional expression of a biologically active fragment of soluble gp130 as an ELP-fusion protein in transgenic plants: purification via inverse transition cycling. | ||||||||||
| Author: | Lin, Meng|Rose-John, Stefan|Grotzinger, Joachim|Conrad, Udo|Scheller, Jurgen | ||||||||||
| PMID: | 16716147 | ||||||||||
| 22. | |||||||||||
| Journal: | World J Gastroenterol. 2006 Jun 14;12(22):3512-22. | ||||||||||
| Title: | Biliary wound healing, ductular reactions, and IL-6/gp130 signaling in the development of liver disease. | ||||||||||
| Author: | Demetris, A-J|Lunz, John-G 3rd|Specht, Susan|Nozaki, Isao | ||||||||||
| PMID: | 16773708 | ||||||||||
| 23. | |||||||||||
| Journal: | Gastroenterology. 2006 Jul;131(1):179-93. | ||||||||||
| Title: | Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. | ||||||||||
| Author: | Ogata, Hisanobu|Kobayashi, Takashi|Chinen, Takatoshi|Takaki, Hiromi|Sanada, Takahito|Minoda, Yasumasa|Koga, Keiko|Takaesu, Giichi|Maehara, Yoshihiko|Iida, Mitsuo|Yoshimura, Akihiko | ||||||||||
| PMID: | 16831601 | ||||||||||
| 24. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2006 Jul;9(4):349-51. | ||||||||||
| Title: | [Relationship of hypoxia-induced factor with tumor angiogenesis in early liver metastasis in colonic cancer]. | ||||||||||
| Author: | Liang, Hao-hui|Wang, Cheng-you|Xu, Min|Cheng, Shu-bang | ||||||||||
| PMID: | 16886122 | ||||||||||
| 25. | |||||||||||
| Journal: | Hepatology. 2006 Oct;44(4):936-44. | ||||||||||
| Title: | HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice. | ||||||||||
| Author: | Kawamura, Hiroki|Govindarajan, Sugantha|Aswad, Fred|Machida, Keigo|Lai, Michael M C|Sung, Vicky M-H|Dennert, Gunther | ||||||||||
| PMID: | 17006910 | ||||||||||
| 26. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2006 Dec 8;351(1):253-8. | ||||||||||
| Title: | The interaction of hepatitis B virus X protein and protein phosphatase type 2 Calpha and its effect on IL-6. | ||||||||||
| Author: | Kim, Ji Su|Rho, Bo young|Lee, Tae Ho|Lee, Jae Myun|Kim, Se Jong|Park, Jeon Han | ||||||||||
| PMID: | 17055456 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Transplant. 2006;15(8-9):785-98. | ||||||||||
| Title: | Microencapsulation of engineered cells to deliver sustained high circulating levels of interleukin-6 to study hepatocellular carcinoma progression. | ||||||||||
| Author: | Moran, Diarmuid M|Koniaris, Leonidas G|Jablonski, Elizabeth M|Cahill, Paul A|Halberstadt, Craig R|McKillop, Iain H | ||||||||||
| PMID: | 17269449 | ||||||||||
| 28. | |||||||||||
| Journal: | J Clin Pathol. 2007 Jun;60(6):642-8. | ||||||||||
| Title: | Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma. | ||||||||||
| Author: | Yang, Sheau-Fang|Wang, Shen-Nien|Wu, Chih-Fung|Yeh, Yao-Tsung|Chai, Chee-Yin|Chunag, Shih-Chang|Sheen, Maw-Chang|Lee, King-Teh | ||||||||||
| PMID: | 16901975 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncogene. 2007 Mar 22;26(13):1941-8. | ||||||||||
| Title: | Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals. | ||||||||||
| Author: | Evans, M K|Yu, C-R|Lohani, A|Mahdi, R M|Liu, X|Trzeciak, A R|Egwuagu, C E | ||||||||||
| PMID: | 17001312 | ||||||||||
| 30. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2007 Mar;133(3):145-52. | ||||||||||
| Title: | Roles of EGFR-Stat3 signal pathway in carcinogenesis of experimental hepatoma in rats. | ||||||||||
| Author: | Yu, Xiao Tang|Zhu, Shi Neng|Xu, Zu De|Hu, Xi Qi|Zhu, Teng Fang|Chen, Jie Qing|Lu, Shi Lun | ||||||||||
| PMID: | 17031671 | ||||||||||
| 31. | |||||||||||
| Journal: | Braz J Med Biol Res. 2007 May;40(5):621-31. | ||||||||||
| Title: | TIMP-1 mediates the inhibitory effect of interleukin-6 on the proliferation of a hepatocarcinoma cell line in a STAT3-dependent manner. | ||||||||||
| Author: | Guo, S-Y|Shen, X|Yang, J|Yuan, J|Yang, R-L|Mao, K|Zhao, D-H|Li, C-J | ||||||||||
| PMID: | 17464423 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Biol Ther. 2007 Dec;6(12):1900-7. Epub 2007 Sep 1. | ||||||||||
| Title: | Inhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma. | ||||||||||
| Author: | Lau, Chi Keung|Yang, Zhen Fan|Lam, Shuk Pik|Lam, Chi Tat|Ngai, Patricia|Tam, Ka Ho|Poon, Ronnie Tung-Ping|Fan, Sheung Tat | ||||||||||
| PMID: | 18059167 | ||||||||||
| 33. | |||||||||||
| Journal: | J Surg Res. 2008 Jun 1;147(1):23-33. | ||||||||||
| Title: | Interleukin-6 mediates G(0)/G(1) growth arrest in hepatocellular carcinoma through a STAT 3-dependent pathway. | ||||||||||
| Author: | Moran, Dairmuid M|Mattocks, M Adrian|Cahill, Paul A|Koniaris, Leonidas G|McKillop, Iain H | ||||||||||
| PMID: | 17574577 | ||||||||||
| 34. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2008 May;134(5):551-9. | ||||||||||
| Title: | Stat3 up-regulates expression of nicotinamide N-methyltransferase in human cancer cells. | ||||||||||
| Author: | Tomida, Mikio|Ohtake, Hideki|Yokota, Takashi|Kobayashi, Yasuhito|Kurosumi, Masafumi | ||||||||||
| PMID: | 17922140 | ||||||||||
| 35. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2445-50. | ||||||||||
| Title: | Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling. | ||||||||||
| Author: | Tang, Yi|Kitisin, Krit|Jogunoori, Wilma|Li, Cuiling|Deng, Chu-Xia|Mueller, Susette C|Ressom, Habtom W|Rashid, Asif|He, Aiwu Ruth|Mendelson, Jonathan S|Jessup, John M|Shetty, Kirti|Zasloff, Michael|Mishra, Bibhuti|Reddy, E P|Johnson, Lynt|Mishra, Lopa | ||||||||||
| PMID: | 18263735 | ||||||||||
| 36. | |||||||||||
| Journal: | Langenbecks Arch Surg. 2008 May;393(3):333-41. | ||||||||||
| Title: | Dual inhibition of Raf and VEGFR2 reduces growth and vascularization of hepatocellular carcinoma in an experimental model. | ||||||||||
| Author: | Lang, Sven Arke|Brecht, Isabel|Moser, Christian|Obed, Aiman|Batt, David|Schlitt, Hans Juergen|Geissler, Edward Kenneth|Stoeltzing, Oliver | ||||||||||
| PMID: | 18297306 | ||||||||||
| 37. | |||||||||||
| Journal: | Clin Cancer Res. 2008 May 1;14(9):2806-12. | ||||||||||
| Title: | Synergistic growth inhibition by 9-cis-retinoic acid plus trastuzumab in human hepatocellular carcinoma cells. | ||||||||||
| Author: | Tatebe, Hideharu|Shimizu, Masahito|Shirakami, Yohei|Tsurumi, Hisashi|Moriwaki, Hisataka | ||||||||||
| PMID: | 18451248 | ||||||||||
| 38. | |||||||||||
| Journal: | Hepatol Res. 2008 Jun;38(6):601-13. | ||||||||||
| Title: | Angiotensin II and epidermal growth factor receptor cross-talk mediated by a disintegrin and metalloprotease accelerates tumor cell proliferation of hepatocellular carcinoma cell lines. | ||||||||||
| Author: | Itabashi, Hidenori|Maesawa, Chihaya|Oikawa, Hiroki|Kotani, Koji|Sakurai, Eiichi|Kato, Kuniyuki|Komatsu, Hideaki|Nitta, Hiroyuki|Kawamura, Hidenobu|Wakabayashi, Go|Masuda, Tomoyuki | ||||||||||
| PMID: | 18452483 | ||||||||||
| 39. | |||||||||||
| Journal: | BMC Cancer. 2008 Jul 23;8:206. | ||||||||||
| Title: | ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo. | ||||||||||
| Author: | Moser, Christian|Lang, Sven A|Mori, Akira|Hellerbrand, Claus|Schlitt, Hans J|Geissler, Edward K|Fogler, William E|Stoeltzing, Oliver | ||||||||||
| PMID: | 18651980 | ||||||||||
| 40. | |||||||||||
| Journal: | J Virol. 2008 Nov;82(22):11066-72. | ||||||||||
| Title: | Hepatitis C virus core protein augments androgen receptor-mediated signaling. | ||||||||||
| Author: | Kanda, Tatsuo|Steele, Robert|Ray, Ranjit|Ray, Ratna B | ||||||||||
| PMID: | 18768969 | ||||||||||
| 41. | |||||||||||
| Journal: | Cell Cycle. 2008 Oct;7(20):3202-10. | ||||||||||
| Title: | Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats. | ||||||||||
| Author: | Bagnyukova, Tetyana V|Tryndyak, Volodymyr P|Muskhelishvili, Levan|Ross, Sharon A|Beland, Frederick A|Pogribny, Igor P | ||||||||||
| PMID: | 18843197 | ||||||||||
| 42. | |||||||||||
| Journal: | Intervirology. 2008;51(6):432-43. | ||||||||||
| Title: | Subcellular mislocalization of mutant hepatitis B X proteins contributes to modulation of STAT/SOCS signaling in hepatocellular carcinoma. | ||||||||||
| Author: | Bock, C-Thomas|Toan, Nguyen L|Koeberlein, Bernd|Song, Le H|Chin, Ruth|Zentgraf, Hanswalter|Kandolf, Reinhard|Torresi, Joseph | ||||||||||
| PMID: | 19321929 | ||||||||||
| 43. | |||||||||||
| Journal: | Gastrointest Cancer Res. 2008 Jul;2(4 Suppl):S27-30. | ||||||||||
| Title: | Liver stem cells and tgf-Beta in hepatic carcinogenesis. | ||||||||||
| Author: | Amin, Rupen|Mishra, Lopa | ||||||||||
| PMID: | 19343145 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Res Treat. 2008 Jun;40(2):53-61. | ||||||||||
| Title: | Cytoplasmic trapping of CXCR4 in hepatocellular carcinoma cell lines. | ||||||||||
| Author: | Kim, Seong-Woo|Kim, Ha-Yon|Song, Ik-Chan|Jin, Seon-Ah|Lee, Hyo-Jin|Yun, Hwan-Jung|Kim, Samyong|Jo, Deog-Yeon | ||||||||||
| PMID: | 19688049 | ||||||||||
| 45. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2009 Mar;63(4):635-42. | ||||||||||
| Title: | Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B. | ||||||||||
| Author: | Zhang, Meixia|Zhang, Hongliang|Sun, Chunyan|Shan, Xiaolei|Yang, Xiaolin|Li-Ling, Jesse|Deng, Yihui | ||||||||||
| PMID: | 18521604 | ||||||||||
| 46. | |||||||||||
| Journal: | Oncogene. 2009 Feb 5;28(5):638-50. | ||||||||||
| Title: | ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression. | ||||||||||
| Author: | Lahsnig, C|Mikula, M|Petz, M|Zulehner, G|Schneller, D|van Zijl, F|Huber, H|Csiszar, A|Beug, H|Mikulits, W | ||||||||||
| PMID: | 19015638 | ||||||||||
| 47. | |||||||||||
| Journal: | Ann N Y Acad Sci. 2009 Feb;1155:206-21. | ||||||||||
| Title: | Inflammation and liver cancer: new molecular links . | ||||||||||
| Author: | Berasain, C|Castillo, J|Perugorria, M J|Latasa, M U|Prieto, J|Avila, M A | ||||||||||
| PMID: | 19250206 | ||||||||||
| 48. | |||||||||||
| Journal: | J Biol Chem. 2009 May 15;284(20):13335-47. | ||||||||||
| Title: | Specific expression and regulation of hepassocin in the liver and down-regulation of the correlation of HNF1alpha with decreased levels of hepassocin in human hepatocellular carcinoma. | ||||||||||
| Author: | Yu, Hai-Tao|Yu, Miao|Li, Chang-Yan|Zhan, Yi-Qun|Xu, Wang-Xiang|Li, Yong-Hui|Li, Wei|Wang, Zhi-Dong|Ge, Chang-Hui|Yang, Xiao-Ming | ||||||||||
| PMID: | 19304666 | ||||||||||
| 49. | |||||||||||
| Journal: | J Exp Med. 2009 Apr 13;206(4):819-31. | ||||||||||
| Title: | Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation. | ||||||||||
| Author: | Hosui, Atsushi|Kimura, Akiko|Yamaji, Daisuke|Zhu, Bing-mei|Na, Risu|Hennighausen, Lothar | ||||||||||
| PMID: | 19332876 | ||||||||||
| 50. | |||||||||||
| Journal: | J Proteome Res. 2009 Aug;8(8):3977-86. | ||||||||||
| Title: | Identifying apoptosis-evasion proteins/pathways in human hepatoma cells via induction of cellular hormesis by UV irradiation. | ||||||||||
| Author: | Hsieh, Sen-Yung|Hsu, Chih-Yun|He, Jung-Ru|Liu, Chiung-Liang|Lo, Shao-Jung|Chen, Ying-Ching|Huang, Hui-Yu | ||||||||||
| PMID: | 19545154 | ||||||||||
| 51. | |||||||||||
| Journal: | J Pathol. 2009 Oct;219(2):253-62. | ||||||||||
| Title: | Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice. | ||||||||||
| Author: | Wang, Ai-Guo|Lee, Dong-Seok|Moon, Hyung-Bae|Kim, Jin-Man|Cho, Kyung-Hyun|Choi, Soo-Ho|Ha, Hye-Lin|Han, Ying-Hao|Kim, Dae-Ghon|Hwang, Soon B|Yu, Dae-Yeul | ||||||||||
| PMID: | 19621337 | ||||||||||
| 52. | |||||||||||
| Journal: | Cancer Biol Ther. 2009 Sep;8(18):1691-8. | ||||||||||
| Title: | Cancer stem cells and hepatocellular carcinoma. | ||||||||||
| Author: | Yao, Zhixing|Mishra, Lopa | ||||||||||
| PMID: | 19901516 | ||||||||||
| 53. | |||||||||||
| Journal: | Int J Cancer. 2010 Mar 1;126(5):1263-74. | ||||||||||
| Title: | High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer. | ||||||||||
| Author: | Jiang, Runqiu|Xia, Yongxiang|Li, Jun|Deng, Lei|Zhao, Liang|Shi, Jian|Wang, Xuehao|Sun, Beicheng | ||||||||||
| PMID: | 19728335 | ||||||||||
| 54. | |||||||||||
| Journal: | Cytokine Growth Factor Rev. 2010 Feb;21(1):11-9. | ||||||||||
| Title: | Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. | ||||||||||
| Author: | Grivennikov, Sergei I|Karin, Michael | ||||||||||
| PMID: | 20018552 | ||||||||||
| 55. | |||||||||||
| Journal: | J Endocrinol. 2010 Mar;204(3):299-309. | ||||||||||
| Title: | GH modulates hepatic epidermal growth factor signaling in the mouse. | ||||||||||
| Author: | Gonzalez, Lorena|Diaz, Ma Eugenia|Miquet, Johanna G|Sotelo, Ana I|Fernandez, Diego|Dominici, Fernando P|Bartke, Andrzej|Turyn, Daniel | ||||||||||
| PMID: | 20032199 | ||||||||||
| 56. | |||||||||||
| Journal: | Cancer Lett. 2010 Jun 28;292(2):197-207. | ||||||||||
| Title: | Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. | ||||||||||
| Author: | Li, Feng|Fernandez, Prasana Priscilla|Rajendran, Peramaiyan|Hui, Kam M|Sethi, Gautam | ||||||||||
| PMID: | 20053498 | ||||||||||
| 57. | |||||||||||
| Journal: | Histol Histopathol. 2010 Mar;25(3):299-307. | ||||||||||
| Title: | Survivin overexpression in HCC and liver cirrhosis differentially correlates with p-STAT3 and E-cadherin. | ||||||||||
| Author: | Peroukides, Stavros|Bravou, Vasiliki|Alexopoulos, Alexandros|Varakis, John|Kalofonos, Haralabos|Papadaki, Helen | ||||||||||
| PMID: | 20054802 | ||||||||||
| 58. | |||||||||||
| Journal: | Cell. 2010 Jan 22;140(2):197-208. | ||||||||||
| Title: | Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. | ||||||||||
| Author: | Park, Eek Joong|Lee, Jun Hee|Yu, Guann-Yi|He, Guobin|Ali, Syed Raza|Holzer, Ryan G|Osterreicher, Christoph H|Takahashi, Hiroyuki|Karin, Michael | ||||||||||
| PMID: | 20141834 | ||||||||||
| 59. | |||||||||||
| Journal: | Cancer Lett. 2010 Aug 1;294(1):118-24. | ||||||||||
| Title: | Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration. | ||||||||||
| Author: | Chan, Kin Tak|Meng, Fan Yan|Li, Qian|Ho, Cheong Yip|Lam, Tsz Shan|To, Yu|Lee, Wai Him|Li, Miao|Chu, Kee Hung|Toh, Melvin | ||||||||||
| PMID: | 20153103 | ||||||||||
| 60. | |||||||||||
| Journal: | Cancer Biother Radiopharm. 2010 Feb;25(1):81-8. | ||||||||||
| Title: | Antitumor activity of the aqueous extract from Sedum sarmentosum Bunge in vitro. | ||||||||||
| Author: | Huang, Dandan|Zhang, Weiyun|Huang, Danqing|Wu, Jianyong | ||||||||||
| PMID: | 20187800 | ||||||||||
| 61. | |||||||||||
| Journal: | Cancer Cell. 2010 Mar 16;17(3):286-97. | ||||||||||
| Title: | Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. | ||||||||||
| Author: | He, Guobin|Yu, Guann-Yi|Temkin, Vladislav|Ogata, Hisanobu|Kuntzen, Christian|Sakurai, Toshiharu|Sieghart, Wolfgang|Peck-Radosavljevic, Markus|Leffert, Hyam L|Karin, Michael | ||||||||||
| PMID: | 20227042 | ||||||||||
| 62. | |||||||||||
| Journal: | Eur J Gastroenterol Hepatol. 2010 Sep;22(9):1106-10. | ||||||||||
| Title: | Tolerance and outcome of patients with unresectable hepatocellular carcinoma treated with sorafenib. | ||||||||||
| Author: | Ozenne, Violaine|Paradis, Valerie|Pernot, Simon|Castelnau, Corinne|Vullierme, Marie-Pierre|Bouattour, Mohamed|Valla, Dominique|Farges, Olivier|Degos, Francoise | ||||||||||
| PMID: | 20300004 | ||||||||||
| 63. | |||||||||||
| Journal: | PLoS One. 2010 Mar 23;5(3):e8649. | ||||||||||
| Title: | Hepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3. | ||||||||||
| Author: | Kim, KyeongJin|Kim, Kook Hwan|Cheong, JaeHun | ||||||||||
| PMID: | 20351777 | ||||||||||
| 64. | |||||||||||
| Journal: | Mol Cell Biochem. 2010 Oct;343(1-2):155-62. | ||||||||||
| Title: | Expression of Oct4 in HCC and modulation to wnt/beta-catenin and TGF-beta signal pathways. | ||||||||||
| Author: | Yuan, FangJun|Zhou, Wenbo|Zou, Can|Zhang, Zhiyun|Hu, Hongsheng|Dai, Zongqing|Zhang, YouShun | ||||||||||
| PMID: | 20549546 | ||||||||||
| 65. | |||||||||||
| Journal: | J Biol Chem. 2010 Aug 27;285(35):27429-39. | ||||||||||
| Title: | Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells. | ||||||||||
| Author: | Liu, Yan|Li, Pui-Kai|Li, Chenglong|Lin, Jiayuh | ||||||||||
| PMID: | 20562100 | ||||||||||
| 66. | |||||||||||
| Journal: | Int J Mol Med. 2010 Aug;26(2):185-91. | ||||||||||
| Title: | Suppression of cell death by the secretory form of N-terminal ERC/mesothelin. | ||||||||||
| Author: | Wang, Tegexibaiyin|Kajino, Kazunori|Abe, Masaaki|Tan, Ke|Maruo, Masumi|Sun, Guodong|Hagiwara, Yoshiaki|Maeda, Masahiro|Hino, Okio | ||||||||||
| PMID: | 20596597 | ||||||||||
| 67. | |||||||||||
| Journal: | Aliment Pharmacol Ther. 2010 Jul;32(2):304-5. | ||||||||||
| Title: | Role of IL-6 activated STAT3 and TNF expression in obesity-associated hepatocellular carcinoma. | ||||||||||
| Author: | Beyazit, Y|Kekilli, M|Kurt, M|Sayilir, A|Tas, A|Onal, I K | ||||||||||
| PMID: | 20636625 | ||||||||||
| 68. | |||||||||||
| Journal: | Hepatology. 2010 Aug;52(2):480-92. | ||||||||||
| Title: | c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair. | ||||||||||
| Author: | Machida, Keigo|Tsukamoto, Hidekazu|Liu, Jian-Chang|Han, Yuan-Ping|Govindarajan, Sugantha|Lai, Michael M C|Akira, Shizuo|Ou, Jing-Hsiung James | ||||||||||
| PMID: | 20683948 | ||||||||||
| 69. | |||||||||||
| Journal: | BMC Cancer. 2010 Aug 19;10:442. | ||||||||||
| Title: | Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase. | ||||||||||
| Author: | Stefanou, Nikolaos|Papanikolaou, Vassilis|Furukawa, Yoichi|Nakamura, Yusuke|Tsezou, Aspasia | ||||||||||
| PMID: | 20723213 | ||||||||||
| 70. | |||||||||||
| Journal: | Oncol Rep. 2010 Oct;24(4):1093-9. | ||||||||||
| Title: | beta-catenin siRNA regulation of apoptosis- and angiogenesis-related gene expression in hepatocellular carcinoma cells: potential uses for gene therapy. | ||||||||||
| Author: | Wang, Xin-Hong|Sun, Xun|Meng, Xiang-Wei|Lv, Zhi-Wu|Du, Ya-Ju|Zhu, Yan|Chen, Jing|Kong, De-Xia|Jin, Shi-Zhu | ||||||||||
| PMID: | 20811694 | ||||||||||
| 71. | |||||||||||
| Journal: | Clin Cancer Res. 2010 Nov 1;16(21):5189-99. | ||||||||||
| Title: | Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3. | ||||||||||
| Author: | Chen, Kuen-Feng|Tai, Wei-Tien|Liu, Tsung-Hao|Huang, Hsiang-Po|Lin, Yu-Chin|Shiau, Chung-Wai|Li, Pui-Kai|Chen, Pei-Jer|Cheng, Ann-Lii | ||||||||||
| PMID: | 20884624 | ||||||||||
| 72. | |||||||||||
| Journal: | Oncol Res. 2010;18(11-12):561-74. | ||||||||||
| Title: | Ad.mda-7 (IL-24) selectively induces apoptosis in hepatocellular carcinoma cell lines, suppresses metastasis, and enhances the effect of doxorubicin on xenograft tumors. | ||||||||||
| Author: | Wang, Cong-Jun|Zhang, Hui|Chen, Kun|Zheng, Jian-Wei|Xiao, Chao-Wen|Ji, Wen-Wei|Yu, Yuan|Hu, Hui-Yi|Li, Yan|Xue, Xin-Bo | ||||||||||
| PMID: | 20939432 | ||||||||||
| 73. | |||||||||||
| Journal: | Hepatology. 2010 Nov;52(5):1713-22. | ||||||||||
| Title: | Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis. | ||||||||||
| Author: | Sharma, Dipali|Wang, Jason|Fu, Ping P|Sharma, Shvetank|Nagalingam, Arumugam|Mells, Jamie|Handy, Jeffrey|Page, Andrew J|Cohen, Cynthia|Anania, Frank A|Saxena, Neeraj K | ||||||||||
| PMID: | 20941777 | ||||||||||
| 74. | |||||||||||
| Journal: | Zhonghua Gan Zang Bing Za Zhi. 2010 Sep;18(9):672-5. | ||||||||||
| Title: | [The role and significance of Wnt/beta-catenin signaling pathway regulating the signaling molecules in hepatocellular carcinoma]. | ||||||||||
| Author: | Wang, Xin-hong|Sun, Xun|Meng, Xiang-wei|Lu, Zhi-wu|Liu, Min-na|Pei, Feng-hua | ||||||||||
| PMID: | 20943078 | ||||||||||
| 75. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Mar 15;17(6):1425-39. | ||||||||||
| Title: | Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo. | ||||||||||
| Author: | Rajendran, Peramaiyan|Ong, Tina H|Chen, Luxi|Li, Feng|Shanmugam, Muthu K|Vali, Shireen|Abbasi, Taher|Kapoor, Shweta|Sharma, Ashish|Kumar, Alan Prem|Hui, Kam M|Sethi, Gautam | ||||||||||
| PMID: | 21131551 | ||||||||||
| 76. | |||||||||||
| Journal: | Cell Res. 2011 Jan;21(1):159-68. | ||||||||||
| Title: | NF-kappaB and STAT3 - key players in liver inflammation and cancer. | ||||||||||
| Author: | He, Guobin|Karin, Michael | ||||||||||
| PMID: | 21187858 | ||||||||||
| 77. | |||||||||||
| Journal: | Neoplasma. 2011;58(2):158-71. | ||||||||||
| Title: | Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy. | ||||||||||
| Author: | Wang, X H|Liu, B R|Qu, B|Xing, H|Gao, S L|Yin, J M|Wang, X F|Cheng, Y Q | ||||||||||
| PMID: | 21275467 | ||||||||||
| 78. | |||||||||||
| Journal: | J Biol Chem. 2011 Mar 25;286(12):10847-55. | ||||||||||
| Title: | Extracellular hepatitis C virus core protein activates STAT3 in human monocytes/macrophages/dendritic cells via an IL-6 autocrine pathway. | ||||||||||
| Author: | Tacke, Robert S|Tosello-Trampont, Annie|Nguyen, Virginia|Mullins, David W|Hahn, Young S | ||||||||||
| PMID: | 21282107 | ||||||||||
| 79. | |||||||||||
| Journal: | Future Oncol. 2011 Feb;7(2):161-4. | ||||||||||
| Title: | Blocking the IL-6-STAT3 signaling pathway: potential liver cancer therapy. | ||||||||||
| Author: | Liu, Yan|Lin, Jiayuh | ||||||||||
| PMID: | 21345134 | ||||||||||
| 80. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2011 Mar;4(3):396-403. | ||||||||||
| Title: | Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice. | ||||||||||
| Author: | Shimizu, Masahito|Sakai, Hiroyasu|Shirakami, Yohei|Yasuda, Yoichi|Kubota, Masaya|Terakura, Daishi|Baba, Atsushi|Ohno, Tomohiko|Hara, Yukihiko|Tanaka, Takuji|Moriwaki, Hisataka | ||||||||||
| PMID: | 21372039 | ||||||||||
| 81. | |||||||||||
| Journal: | Int J Oncol. 2011 May;38(5):1395-402. | ||||||||||
| Title: | Regulation of cancer cell proliferation by caveolin-2 down-regulation and re-expression. | ||||||||||
| Author: | Lee, Sangho|Kwon, Hayeong|Jeong, Kyuho|Pak, Yunbae | ||||||||||
| PMID: | 21373752 | ||||||||||
| 82. | |||||||||||
| Journal: | J Cell Physiol. 2011 Jun;226(6):1632-41. | ||||||||||
| Title: | Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation. | ||||||||||
| Author: | Carlisi, Daniela|D'Anneo, Antonella|Angileri, Liliana|Lauricella, Marianna|Emanuele, Sonia|Santulli, Andrea|Vento, Renza|Tesoriere, Giovanni | ||||||||||
| PMID: | 21413021 | ||||||||||
| 83. | |||||||||||
| Journal: | HPB (Oxford). 2011 Apr;13(4):225-33. | ||||||||||
| Title: | |||||||||||