Primary Site >> Esophagus Cancer
Gene >> STAT3
| 1. | |||||||||||
| Journal: | J Gastroenterol. 2002;37(7):497-503. | ||||||||||
| Title: | Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1. | ||||||||||
| Author: | Ichiba, Makoto|Miyazaki, Yoshiji|Kitamura, Shinji|Kiyohara, Tatsuya|Shinomura, Yasuhisa|Matsuzawa, Yuji | ||||||||||
| PMID: | 12162406 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2003 Oct 30;22(49):7809-18. | ||||||||||
| Title: | Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. | ||||||||||
| Author: | Leu, Chuen-Miin|Wong, Fen-Hwa|Chang, Chungming|Huang, Shiu-Feng|Hu, Cheng-po | ||||||||||
| PMID: | 14586407 | ||||||||||
| 3. | |||||||||||
| Journal: | Ai Zheng. 2007 May;26(5):458-62. | ||||||||||
| Title: | [Expression and clinical significance of COX-2, p-Stat3, and p-Stat5 in esophageal carcinoma]. | ||||||||||
| Author: | Liu, Jun-Ru|Wang, Yuan|Zuo, Lian-Fu|Li, Feng-Lin|Wang, Ying|Liu, Jia-Lin | ||||||||||
| PMID: | 17672932 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Lett. 2008 Nov 18;271(1):85-97. | ||||||||||
| Title: | beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma. | ||||||||||
| Author: | Yan, Shuang|Zhou, Cuiqi|Zhang, Wei|Zhang, Guo|Zhao, Xuejian|Yang, Shangbin|Wang, Yihua|Lu, Ning|Zhu, Hongxia|Xu, Ningzhi | ||||||||||
| PMID: | 18602747 | ||||||||||
| 5. | |||||||||||
| Journal: | Cell Physiol Biochem. 2010;26(6):849-58. | ||||||||||
| Title: | Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells. | ||||||||||
| Author: | Chen, Qing-Jiang|Zhang, Ming-Zhi|Wang, Le-Xin | ||||||||||
| PMID: | 21220916 | ||||||||||
| 6. | |||||||||||
| Journal: | Gastroenterology. 2012 Mar;142(3):521-530.e3. | ||||||||||
| Title: | Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells. | ||||||||||
| Author: | Zhang, Yu|Du, Xiao-Li|Wang, Cheng-Ji|Lin, De-Chen|Ruan, Xia|Feng, Yan-Bin|Huo, Yan-Qiu|Peng, Haiyong|Cui, Jing-Lu|Zhang, Tong-Tong|Wang, Yong-Quan|Zhang, Hongbing|Zhan, Qi-Min|Wang, Ming-Rong | ||||||||||
| PMID: | 22108192 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer. 2012 Aug 15;118(16):4074-89. | ||||||||||
| Title: | The role of DNA methyltransferase 3b in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Chen, Miao-Fen|Lu, Ming-Shian|Lin, Paul-Yang|Chen, Ping-Tsung|Chen, Wen-Cheng|Lee, Kuan-Der | ||||||||||
| PMID: | 22213175 | ||||||||||
| 8. | |||||||||||
| Journal: | Clin Exp Metastasis. 2012 Aug;29(6):615-24. | ||||||||||
| Title: | Phosphorylation of signal transducer and activator of transcription 3 (STAT3) correlates with Her-2 status, carbonic anhydrase 9 expression and prognosis in esophageal cancer. | ||||||||||
| Author: | Schoppmann, Sebastian F|Jesch, Bettina|Friedrich, Julia|Jomrich, Gerd|Maroske, Florian|Birner, Peter | ||||||||||
| PMID: | 22484976 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Oncol. 2012 Jul;41(1):61-6. | ||||||||||
| Title: | PSK induces apoptosis through the inhibition of activated STAT3 in human esophageal carcinoma cells. | ||||||||||
| Author: | Umehara, Seiji|Fujiwara, Hitoshi|Shiozaki, Atsushi|Todo, Momoko|Furutani, Akinobu|Yoneda, Masayuki|Ikai, Atsushi|Tada, Hiroyuki|Komatsu, Shuhei|Ichikawa, Daisuke|Okamoto, Kazuma|Ochiai, Toshiya|Kokuba, Yukihito|Otsuji, Eigo | ||||||||||
| PMID: | 22552778 | ||||||||||
| 10. | |||||||||||
| Journal: | Clin Cancer Res. 2012 Sep 15;18(18):5144-53. | ||||||||||
| Title: | Let-7 expression is a significant determinant of response to chemotherapy through the regulation of IL-6/STAT3 pathway in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Sugimura, Keijiro|Miyata, Hiroshi|Tanaka, Koji|Hamano, Rie|Takahashi, Tsuyoshi|Kurokawa, Yukinori|Yamasaki, Makoto|Nakajima, Kiyokazu|Takiguchi, Shuji|Mori, Masaki|Doki, Yuichiro | ||||||||||
| PMID: | 22847808 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS One. 2013 Oct 9;8(10):e75254. | ||||||||||
| Title: | Inhibiting interleukin-19 activity ameliorates esophageal squamous cell carcinoma progression. | ||||||||||
| Author: | Hsing, Chung-Hsi|Kwok, Franky Antonius|Cheng, Hung-Chi|Li, Chien-Feng|Chang, Ming-Shi | ||||||||||
| PMID: | 24130695 | ||||||||||
| 12. | |||||||||||
| Journal: | Mol Cancer. 2013 Apr 5;12:26. | ||||||||||
| Title: | IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus. | ||||||||||
| Author: | Chen, Miao-Fen|Chen, Ping-Tsung|Lu, Ming Shian|Lin, Paul Yang|Chen, Wen-Cheng|Lee, Kuan-Der | ||||||||||
| PMID: | 23561329 | ||||||||||
| 13. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2014 Feb;306(3):G183-90. | ||||||||||
| Title: | Apurinic/apyrimidinic endonuclease-1 is associated with angiogenesis and VEGF production via upregulation of COX-2 expression in esophageal cancer tissues. | ||||||||||
| Author: | Nagoya, Hiroyuki|Futagami, Seiji|Shimpuku, Mayumi|Tatsuguchi, Atsushi|Wakabayashi, Taiga|Yamawaki, Hiroshi|Kodaka, Yasuhiro|Kawagoe, Tetsuro|Watarai, Yasuhiko|Makino, Hiroshi|Miyashita, Masao|Tsuchiya, Shinichi|Crowe, Sheila E|Sakamoto, Choitsu | ||||||||||
| PMID: | 24284961 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Med Rep. 2014 Jun;9(6):2400-4. | ||||||||||
| Title: | Downregulation of LKB1 suppresses Stat3 activity to promote the proliferation of esophageal carcinoma cells. | ||||||||||
| Author: | Wang, Yu-Qi|Dai, Wei-Min|Chu, Xiang-Yang|Yang, Bo|Zhao, Ming|Sun, Yu'e | ||||||||||
| PMID: | 24676538 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2014 Mar 15;7(4):1524-33. eCollection 2014. | ||||||||||
| Title: | RNA-seq reveals determinants of sensitivity to chemotherapy drugs in esophageal carcinoma cells. | ||||||||||
| Author: | Yang, Li-Xin|Li, Bai-Ling|Liu, Xiao-Hong|Yuan, Yang|Lu, Chao-Jing|Chen, Rui|Zhao, Jian | ||||||||||
| PMID: | 24817948 | ||||||||||
| 16. | |||||||||||
| Journal: | Tumour Biol. 2014 Oct;35(10):9793-9. | ||||||||||
| Title: | STAT3 inhibitor NSC74859 radiosensitizes esophageal cancer via the downregulation of HIF-1alpha. | ||||||||||
| Author: | Zhang, Chi|Yang, Xi|Zhang, Qu|Guo, Qing|He, Jia|Qin, Qin|Zhu, Hongcheng|Liu, Jia|Zhan, Liangliang|Lu, Jing|Liu, Zheming|Xu, Liping|Ma, Jianxin|Dai, Shengbin|Cheng, Hongyan|Sun, Xinchen | ||||||||||
| PMID: | 24981247 | ||||||||||
| 17. | |||||||||||
| Journal: | J Mol Med (Berl). 2014 Nov;92(11):1209-23. | ||||||||||
| Title: | ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways. | ||||||||||
| Author: | Fichter, Christiane D|Gudernatsch, Verena|Przypadlo, Camilla M|Follo, Marie|Schmidt, Gudula|Werner, Martin|Lassmann, Silke | ||||||||||
| PMID: | 25091467 | ||||||||||
| 18. | |||||||||||
| Journal: | Cancer Lett. 2014 Nov 1;354(1):142-52. | ||||||||||
| Title: | Activating transcription factor 4 mediates a multidrug resistance phenotype of esophageal squamous cell carcinoma cells through transactivation of STAT3 expression. | ||||||||||
| Author: | Zhu, Hongwu|Chen, Xiong|Chen, Bin|Chen, Bei|Fan, Jianyong|Song, Weibing|Xie, Ziying|Jiang, Dan|Li, Qiuqiong|Zhou, Meihua|Sun, Dayong|Zhao, Yagang | ||||||||||
| PMID: | 25130172 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncotarget. 2014 Sep 30;5(18):8716-28. | ||||||||||
| Title: | IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus. | ||||||||||
| Author: | Chen, Miao-Fen|Kuan, Feng-Che|Yen, Tzu-Chen|Lu, Ming-Shian|Lin, Paul-Yang|Chung, Yi-Hsiu|Chen, Wen-Cheng|Lee, Kuan-Der | ||||||||||
| PMID: | 25238263 | ||||||||||
| 20. | |||||||||||
| Journal: | Pathol Res Pract. 2015 Jun;211(6):426-34. | ||||||||||
| Title: | Nimesulide inhibits the growth of human esophageal carcinoma cells by inactivating the JAK2/STAT3 pathway. | ||||||||||
| Author: | Liu, Jun-Ru|Wu, Wen-Juan|Liu, Shu-Xia|Zuo, Lian-Fu|Wang, Yuan|Yang, Jian-Zhu|Nan, Yue-Min | ||||||||||
| PMID: | 25724470 | ||||||||||
| 21. | |||||||||||
| Journal: | World J Surg Oncol. 2015 Nov 9;13:314. | ||||||||||
| Title: | Expression of activated signal transducer and activator of transcription-3 as a predictive and prognostic marker in advanced esophageal squamous cell carcinoma. | ||||||||||
| Author: | Huang, Chuying|Wang, Li|Yang, Xibiao|Lai, Lin|Chen, Dian|Duan, Chunyan | ||||||||||
| PMID: | 26553224 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Oncol. 2015 Dec;47(6):2255-63. | ||||||||||
| Title: | Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells. | ||||||||||
| Author: | Hadisaputri, Yuni Elsa|Miyazaki, Tatsuya|Suzuki, Shigemasa|Kubo, Norio|Zuhrotun, Ade|Yokobori, Takehiko|Abdulah, Rizky|Yazawa, Shin|Kuwano, Hiroyuki | ||||||||||
| PMID: | 26498695 | ||||||||||
| 23. | |||||||||||
| Journal: | BMC Cancer. 2015 Apr 19;15:306. | ||||||||||
| Title: | STAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells. | ||||||||||
| Author: | Cheng, Yan|Li, Yang|Nian, Yuanyuan|Liu, Dong|Dai, Fei|Zhang, Jun | ||||||||||
| PMID: | 25928665 | ||||||||||
| 24. | |||||||||||
| Journal: | Mol Cancer Ther. 2015 Jun;14(6):1365-75. | ||||||||||
| Title: | 1alpha,25-Dihydroxyvitamin D3 Inhibits Esophageal Squamous Cell Carcinoma Progression by Reducing IL6 Signaling. | ||||||||||
| Author: | Chen, Ping-Tsung|Hsieh, Ching-Chuan|Wu, Chun-Te|Yen, Tzu-Chen|Lin, Paul-Yang|Chen, Wen-Cheng|Chen, Miao-Fen | ||||||||||
| PMID: | 25824337 | ||||||||||
| 25. | |||||||||||
| Journal: | PLoS One. 2015 May 29;10(5):e0127356. | ||||||||||
| Title: | Prognostic Role of Phospho-STAT3 in Patients with Cancers of the Digestive System: A Systematic Review and Meta-Analysis. | ||||||||||
| Author: | Li, Mu-xing|Bi, Xin-yu|Huang, Zhen|Zhao, Jian-jun|Han, Yue|Li, Zhi-Yu|Zhang, Ye-fan|Li, Yuan|Chen, Xiao|Hu, Xu-hui|Zhao, Hong|Cai, Jian-qiang | ||||||||||
| PMID: | 26024373 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Cancer. 2016 May 17;15(1):40. | ||||||||||
| Title: | Reciprocal activation between STAT3 and miR-181b regulates the proliferation of esophageal cancer stem-like cells via the CYLD pathway. | ||||||||||
| Author: | Xu, Dan-Dan|Zhou, Peng-Jun|Wang, Ying|Zhang, Li|Fu, Wu-Yu|Ruan, Bi-Bo|Xu, Hai-Peng|Hu, Chao-Zhi|Tian, Lu|Qin, Jin-Hong|Wang, Sheng|Wang, Xiao|Li, Yi-Cheng|Liu, Qiu-Ying|Ren, Zhe|Zhang, Rong|Wang, Yi-Fei | ||||||||||
| PMID: | 27189061 | ||||||||||
| 27. | |||||||||||
| Journal: | PLoS One. 2016 Nov 22;11(11):e0166453. | ||||||||||
| Title: | The Synthetic beta-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways. | ||||||||||
| Author: | Chiu, Wen-Chin|Lee, Yi-Chen|Su, Yu-Han|Wang, Yen-Yun|Tsai, Chun-Hao|Hou, Yi-An|Wang, Chie-Hong|Huang, Ying-Fong|Huang, Chih-Jen|Chou, Shah-Hwa|Hsieh, Pei-Wen|Yuan, Shyng-Shiou F | ||||||||||
| PMID: | 27875549 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncol Lett. 2016 Nov;12(5):3598-3608. Epub 2016 Sep 5. | ||||||||||
| Title: | Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells. | ||||||||||
| Author: | Lu, Qiu-Ping|Chen, Wen-Dan|Peng, Jie-Ren|Xu, Yao-Dong|Cai, Qian|Feng, Gong-Kan|Ding, Ke|Zhu, Xiao-Feng|Guan, Zhong | ||||||||||
| PMID: | 27900042 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncotarget. 2017 Sep 12;8(51):88719-88729. | ||||||||||
| Title: | Constitutive activated STAT3 is an essential regulator and therapeutic target in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Tian, Fang|Yang, Xiawen|Liu, Ying|Yuan, Xiao|Fan, Tianli|Zhang, Fanmiao|Zhao, Jimin|Lu, Jing|Jiang, Yanan|Dong, Ziming|Yang, Yili | ||||||||||
| PMID: | 29179470 | ||||||||||
| 30. | |||||||||||
| Journal: | Environ Toxicol Pharmacol. 2017 Sep;54:7-13. | ||||||||||
| Title: | Icariin exerts inhibitory effects on the growth and metastasis of KYSE70 human esophageal carcinoma cells via PI3K/AKT and STAT3 pathways. | ||||||||||
| Author: | Gu, Zhen-Fang|Zhang, Zi-Teng|Wang, Jun-Ye|Xu, Bao-Bin | ||||||||||
| PMID: | 28667862 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Sci. 2017 May;108(5):910-917. | ||||||||||
| Title: | Nardilysin promotes hepatocellular carcinoma through activation of signal transducer and activator of transcription 3. | ||||||||||
| Author: | Kasai, Yosuke|Toriguchi, Kan|Hatano, Etsuro|Nishi, Kiyoto|Ohno, Mikiko|Yoh, Tomoaki|Fukuyama, Keita|Nishio, Takahiro|Okuno, Masayuki|Iwaisako, Keiko|Seo, Satoru|Taura, Kojiro|Kurokawa, Masato|Kunichika, Makoto|Uemoto, Shinji|Nishi, Eiichiro | ||||||||||
| PMID: | 28207963 | ||||||||||
| 32. | |||||||||||
| Journal: | Dig Dis Sci. 2018 Jan;63(1):126-134. | ||||||||||
| Title: | Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway. | ||||||||||
| Author: | Hu, Xue|Ma, Jingjing|Vikash, Vikash|Li, Jiao|Wu, Dandan|Liu, Ya|Zhang, Jixiang|Dong, Weiguo | ||||||||||
| PMID: | 29197940 | ||||||||||
| 33. | |||||||||||
| Journal: | Cell Death Dis. 2018 Jan 16;9(2):17. | ||||||||||
| Title: | Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling. | ||||||||||
| Author: | Cao, Ying-Ya|Yu, Jing|Liu, Ting-Ting|Yang, Kai-Xia|Yang, Li-Yan|Chen, Qun|Shi, Feng|Hao, Jia-Jie|Cai, Yan|Wang, Ming-Rong|Lu, Wei-Hua|Zhang, Yu | ||||||||||
| PMID: | 29339720 | ||||||||||
| 34. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2018 Jan;22(2):551-560. | ||||||||||
| Title: | The effect of curcumin on cell adhesion of human esophageal cancer cell. | ||||||||||
| Author: | Zheng, B-Z|Liu, T-D|Chen, G|Zhang, J-X|Kang, X | ||||||||||
| PMID: | 29424917 | ||||||||||
| 35. | |||||||||||
| Journal: | Cancer Cell Int. 2018 Apr 4;18:53. | ||||||||||
| Title: | Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells. | ||||||||||
| Author: | Zhou, Chao|Ma, Jie|Su, Mengyuan|Shao, Dan|Zhao, Jianan|Zhao, Tongjian|Song, Zhuoyao|Meng, Yan|Jiao, Ping | ||||||||||
| PMID: | 29636641 | ||||||||||
| 36. | |||||||||||
| Journal: | Cancer Res. 2018 Sep 1;78(17):4957-4970. | ||||||||||
| Title: | IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment. | ||||||||||
| Author: | Karakasheva, Tatiana A|Lin, Eric W|Tang, Qiaosi|Qiao, Edmund|Waldron, Todd J|Soni, Monica|Klein-Szanto, Andres J|Sahu, Varun|Basu, Devraj|Ohashi, Shinya|Baba, Kiichiro|Giaccone, Zachary T|Walker, Sarah R|Frank, David A|Wileyto, E Paul|Long, Qi|Dunagin, Ma | ||||||||||
| PMID: | 29976575 | ||||||||||
| 37. | |||||||||||
| Journal: | Cancer Sci. 2018 Aug 10. | ||||||||||
| Title: | TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway. | ||||||||||
| Author: | Xiong, Dian|Jin, Chun|Ye, Xudong|Qiu, Baiquan|Jianjun, Xu|Zhu, Shuqiang|Xiang, Long|Wu, Haibo|Yongbing, Wu | ||||||||||
| PMID: | 30098109 | ||||||||||
| 38. | |||||||||||
| Journal: | Front Pharmacol. 2018 Aug 21;9:820. | ||||||||||
| Title: | The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2-STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells. | ||||||||||
| Author: | Wang, Ying|Zhou, Pengjun|Qin, Shurong|Xu, Dandan|Liu, Yukun|Fu, Wuyu|Ruan, Bibo|Zhang, Li|Zhang, Yi|Wang, Xiao|Pan, Yuwei|Wang, Sheng|Yan, Haizhao|Qin, Jinhong|Wang, Xiaoyan|Liu, Qiuying|Du, Zhiyun|Liu, Zhong|Wang, Yifei | ||||||||||
| PMID: | 30186159 | ||||||||||
| 39. | |||||||||||
| Journal: | J Cancer Res Ther. 2018 Sep;14(Supplement):S758-S760. | ||||||||||
| Title: | Clinical significance of interleukin-6 in diagnosis of lung, oral, esophageal, and gall bladder carcinomas. | ||||||||||
| Author: | Vinocha, Anjali|Grover, Rajesh K|Deepak, Rani | ||||||||||
| PMID: | 30249899 | ||||||||||