Primary Site >> Esophagus Cancer

Gene >> STAT3

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Ref: Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1.
PMID: 12162406
Ref: Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways.
PMID: 14586407
Ref: [Expression and clinical significance of COX-2, p-Stat3, and p-Stat5 in esophageal carcinoma].
PMID: 17672932
Ref: beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma.
PMID: 18602747
Ref: Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells.
PMID: 21220916
Ref: Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells.
PMID: 22108192
Ref: The role of DNA methyltransferase 3b in esophageal squamous cell carcinoma.
PMID: 22213175
Ref: Phosphorylation of signal transducer and activator of transcription 3 (STAT3) correlates with Her-2 status, carbonic anhydrase 9 expression and prognosis in esophageal cancer.
PMID: 22484976
Ref: PSK induces apoptosis through the inhibition of activated STAT3 in human esophageal carcinoma cells.
PMID: 22552778
Ref: Let-7 expression is a significant determinant of response to chemotherapy through the regulation of IL-6/STAT3 pathway in esophageal squamous cell carcinoma.
PMID: 22847808
Ref: IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus.
PMID: 23561329
Ref: Inhibiting interleukin-19 activity ameliorates esophageal squamous cell carcinoma progression.
PMID: 24130695
Ref: Apurinic/apyrimidinic endonuclease-1 is associated with angiogenesis and VEGF production via upregulation of COX-2 expression in esophageal cancer tissues.
PMID: 24284961
Ref: Downregulation of LKB1 suppresses Stat3 activity to promote the proliferation of esophageal carcinoma cells.
PMID: 24676538
Ref: RNA-seq reveals determinants of sensitivity to chemotherapy drugs in esophageal carcinoma cells.
PMID: 24817948
Ref: STAT3 inhibitor NSC74859 radiosensitizes esophageal cancer via the downregulation of HIF-1alpha.
PMID: 24981247
Ref: ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways.
PMID: 25091467
Ref: Activating transcription factor 4 mediates a multidrug resistance phenotype of esophageal squamous cell carcinoma cells through transactivation of STAT3 expression.
PMID: 25130172
Ref: IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus.
PMID: 25238263
Ref: Nimesulide inhibits the growth of human esophageal carcinoma cells by inactivating the JAK2/STAT3 pathway.
PMID: 25724470
Ref: 1alpha,25-Dihydroxyvitamin D3 Inhibits Esophageal Squamous Cell Carcinoma Progression by Reducing IL6 Signaling.
PMID: 25824337
Ref: STAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells.
PMID: 25928665
Ref: Prognostic Role of Phospho-STAT3 in Patients with Cancers of the Digestive System: A Systematic Review and Meta-Analysis.
PMID: 26024373
Ref: Molecular characterization of antitumor effects of the rhizome extract from Curcuma zedoaria on human esophageal carcinoma cells.
PMID: 26498695
Ref: Expression of activated signal transducer and activator of transcription-3 as a predictive and prognostic marker in advanced esophageal squamous cell carcinoma.
PMID: 26553224
Ref: Reciprocal activation between STAT3 and miR-181b regulates the proliferation of esophageal cancer stem-like cells via the CYLD pathway.
PMID: 27189061
Ref: The Synthetic beta-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
PMID: 27875549
Ref: Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells.
PMID: 27900042
Ref: Nardilysin promotes hepatocellular carcinoma through activation of signal transducer and activator of transcription 3.
PMID: 28207963
Ref: Icariin exerts inhibitory effects on the growth and metastasis of KYSE70 human esophageal carcinoma cells via PI3K/AKT and STAT3 pathways.
PMID: 28667862
Ref: Constitutive activated STAT3 is an essential regulator and therapeutic target in esophageal squamous cell carcinoma.
PMID: 29179470
Ref: Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway.
PMID: 29197940
Ref: Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling.
PMID: 29339720
Ref: The effect of curcumin on cell adhesion of human esophageal cancer cell.
PMID: 29424917
Ref: Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells.
PMID: 29636641
Ref: IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment.
PMID: 29976575
Ref: TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway.
PMID: 30098109
Ref: The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2-STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells.
PMID: 30186159
Ref: Clinical significance of interleukin-6 in diagnosis of lung, oral, esophageal, and gall bladder carcinomas.
PMID: 30249899