Primary Site >> Biliary tract Cancer
Gene >> STAT3
| 1. | |||||||||||
| Journal: | Hepatology. 2005 Dec;42(6):1329-38. | ||||||||||
| Title: | Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells. | ||||||||||
| Author: | Isomoto, Hajime|Kobayashi, Shogo|Werneburg, Nathan W|Bronk, Steve F|Guicciardi, Maria Eugenia|Frank, David A|Gores, Gregory J | ||||||||||
| PMID: | 16317687 | ||||||||||
| 2. | |||||||||||
| Journal: | Hepatology. 2009 Dec;50(6):1861-70. | ||||||||||
| Title: | Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. | ||||||||||
| Author: | Blechacz, Boris R A|Smoot, Rory L|Bronk, Steven F|Werneburg, Nathan W|Sirica, Alphonse E|Gores, Gregory J | ||||||||||
| PMID: | 19821497 | ||||||||||
| 3. | |||||||||||
| Journal: | World J Gastroenterol. 2010 Jan 14;16(2):156-66. | ||||||||||
| Title: | Treatment of biliary tract cancer with NVP-AEW541: mechanisms of action and resistance. | ||||||||||
| Author: | Wolf, Samuel|Lorenz, Jana|Mossner, Joachim|Wiedmann, Marcus | ||||||||||
| PMID: | 20066734 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Sci. 2010 Aug;101(8):1913-9. | ||||||||||
| Title: | Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Hasita, Horlad|Komohara, Yoshihiro|Okabe, Hirohisa|Masuda, Toshiro|Ohnishi, Koji|Lei, Xiao F|Beppu, Toru|Baba, Hideo|Takeya, Motohiro | ||||||||||
| PMID: | 20545696 | ||||||||||
| 5. | |||||||||||
| Journal: | J Gastroenterol. 2011 Jun;46(6):779-89. | ||||||||||
| Title: | Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells. | ||||||||||
| Author: | Sugiyama, Hiroaki|Onuki, Kenichiro|Ishige, Kazunori|Baba, Nobue|Ueda, Tetsuya|Matsuda, Sachiko|Takeuchi, Kaoru|Onodera, Masafumi|Nakanuma, Yasuni|Yamato, Masayuki|Yamamoto, Masakazu|Hyodo, Ichinosuke|Shoda, Junichi | ||||||||||
| PMID: | 21331764 | ||||||||||
| 6. | |||||||||||
| Journal: | Hepatology. 2012 Jan;55(1):108-20. | ||||||||||
| Title: | Hepatitis B virus X (HBx) induces tumorigenicity of hepatic progenitor cells in 3,5-diethoxycarbonyl-1,4-dihydrocollidine-treated HBx transgenic mice. | ||||||||||
| Author: | Wang, Chao|Yang, Wen|Yan, He-Xin|Luo, Tao|Zhang, Jian|Tang, Liang|Wu, Fu-Quan|Zhang, Hui-Lu|Yu, Le-Xing|Zheng, Long-Yi|Li, Yu-Qiong|Dong, Wei|He, Ya-Qin|Liu, Qiong|Zou, Shan-Shan|Lin, Yan|Hu, Liang|Li, Zhong|Wu, Meng-Chao|Wang, Hong-Yang | ||||||||||
| PMID: | 21932402 | ||||||||||
| 7. | |||||||||||
| Journal: | Clin Exp Metastasis. 2013 Feb;30(2):177-87. | ||||||||||
| Title: | Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma. | ||||||||||
| Author: | Hong, Sun Mi|Park, Chang Wook|Cha, Hyung Jin|Kwon, Jung Hee|Yun, Young Sung|Lee, Nam Gyu|Kim, Dae-Ghon|Nam, Hong Gil|Choi, Kwan Yong | ||||||||||
| PMID: | 22875246 | ||||||||||
| 8. | |||||||||||
| Journal: | Gastroenterology. 2013 Apr;144(4):829-40. | ||||||||||
| Title: | Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes. | ||||||||||
| Author: | Sia, Daniela|Hoshida, Yujin|Villanueva, Augusto|Roayaie, Sasan|Ferrer, Joana|Tabak, Barbara|Peix, Judit|Sole, Manel|Tovar, Victoria|Alsinet, Clara|Cornella, Helena|Klotzle, Brandy|Fan, Jian-Bing|Cotsoglou, Christian|Thung, Swan N|Fuster, Josep|Waxman, Sam | ||||||||||
| PMID: | 23295441 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 2013 Oct 10;32(41):4861-70. | ||||||||||
| Title: | Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies. | ||||||||||
| Author: | Sia, D|Tovar, V|Moeini, A|Llovet, J M | ||||||||||
| PMID: | 23318457 | ||||||||||
| 10. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2013 Mar;51(3):261-5. | ||||||||||
| Title: | [Molecular mechanism of gamma-aminobutyric acid inhibitory on the growth of cholangiocarcinoma QBC939 cell line]. | ||||||||||
| Author: | Zhu, Cheng-lin|Huang, Qiang|Liu, Chen-hai|Xie, Fang|Zhu, Kai | ||||||||||
| PMID: | 23859331 | ||||||||||
| 11. | |||||||||||
| Journal: | Hepatology. 2014 Mar;59(3):935-46. | ||||||||||
| Title: | Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma. | ||||||||||
| Author: | Zheng, Tongsen|Hong, Xuehui|Wang, Jiabei|Pei, Tiemin|Liang, Yingjian|Yin, Dalong|Song, Ruipeng|Song, Xuan|Lu, Zhaoyang|Qi, Shuyi|Liu, Jiaren|Sun, Boshi|Xie, Changming|Pan, Shangha|Li, Yuejin|Luo, Xiaohe|Li, Shuai|Fang, Xiang|Bhatta, Nishant|Jiang, Hongchi | ||||||||||
| PMID: | 24037855 | ||||||||||
| 12. | |||||||||||
| Journal: | Phytother Res. 2014 Jun;28(6):841-8. | ||||||||||
| Title: | Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway. | ||||||||||
| Author: | Senggunprai, Laddawan|Kukongviriyapan, Veerapol|Prawan, Auemduan|Kukongviriyapan, Upa | ||||||||||
| PMID: | 24038588 | ||||||||||
| 13. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2014;15(12):5071-6. | ||||||||||
| Title: | Luteolin arrests cell cycling, induces apoptosis and inhibits the JAK/STAT3 pathway in human cholangiocarcinoma cells. | ||||||||||
| Author: | Aneknan, Ploypailin|Kukongviriyapan, Veerapol|Prawan, Auemduan|Kongpetch, Sarinya|Sripa, Banchob|Senggunprai, Laddawan | ||||||||||
| PMID: | 24998588 | ||||||||||
| 14. | |||||||||||
| Journal: | BMC Complement Altern Med. 2014 Jul 19;14:254. | ||||||||||
| Title: | Differentiation therapy: sesamin as an effective agent in targeting cancer stem-like side population cells of human gallbladder carcinoma. | ||||||||||
| Author: | Kong, Xiang|Ma, Ming-zhe|Zhang, Yan|Weng, Ming-zhe|Gong, Wei|Guo, Li-qun|Zhang, Jun-xiu|Wang, Guo-dong|Su, Qing|Quan, Zhi-wei|Yang, Jie-ren | ||||||||||
| PMID: | 25038821 | ||||||||||
| 15. | |||||||||||
| Journal: | J Hepatobiliary Pancreat Sci. 2014 Oct;21(10):767-76. | ||||||||||
| Title: | STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression. | ||||||||||
| Author: | Dokduang, Hasaya|Techasen, Anchalee|Namwat, Nisana|Khuntikeo, Narong|Pairojkul, Chawalit|Murakami, Yoshinori|Loilome, Watcharin|Yongvanit, Puangrat | ||||||||||
| PMID: | 25044480 | ||||||||||
| 16. | |||||||||||
| Journal: | Am J Pathol. 2014 Oct;184(10):2828-39. | ||||||||||
| Title: | miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator. | ||||||||||
| Author: | Zhu, Hanqing|Han, Chang|Lu, Dongdong|Wu, Tong | ||||||||||
| PMID: | 25239565 | ||||||||||
| 17. | |||||||||||
| Journal: | BMC Cancer. 2014 Oct 25;14:783. | ||||||||||
| Title: | FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling. | ||||||||||
| Author: | Lu, Zhaoyang|Wang, Jiabei|Zheng, Tongsen|Liang, Yingjian|Yin, Dalong|Song, Ruipeng|Pei, Tiemin|Pan, Shangha|Jiang, Hongchi|Liu, Lianxin | ||||||||||
| PMID: | 25344679 | ||||||||||
| 18. | |||||||||||
| Journal: | Med Oncol. 2015 Apr;32(4):105. | ||||||||||
| Title: | Enhanced expression of suppresser of cytokine signaling 3 inhibits the IL-6-induced epithelial-to-mesenchymal transition and cholangiocarcinoma cell metastasis. | ||||||||||
| Author: | Zhou, Qing-Xin|Jiang, Xing-Ming|Wang, Zhi-Dong|Li, Chun-Long|Cui, Yun-Fu | ||||||||||
| PMID: | 25744243 | ||||||||||
| 19. | |||||||||||
| Journal: | J Toxicol Pathol. 2015 Apr;28(2):79-87. | ||||||||||
| Title: | Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats. | ||||||||||
| Author: | Zhang, Fan|Li, Lianhong|Yang, Xingwu|Wang, Bo|Zhao, Jinyao|Lu, Shilun|Yu, Xiaotang | ||||||||||
| PMID: | 26028817 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Oncol. 2016 May;48(5):2025-34. | ||||||||||
| Title: | Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines. | ||||||||||
| Author: | Muller, Alena|Barat, Samarpita|Chen, Xi|Bui, Khac Cuong|Bozko, Przemyslaw|Malek, Nisar P|Plentz, Ruben R | ||||||||||
| PMID: | 26935541 | ||||||||||
| 21. | |||||||||||
| Journal: | J Hepatobiliary Pancreat Sci. 2016 Jul;23(7):397-405. | ||||||||||
| Title: | Anoikis-resistant cholangiocarcinoma cells display aggressive characteristics and increase STAT3 activation. | ||||||||||
| Author: | Huyen, Nguyen Thi Bich|Prachayasittikul, Virapong|Chan-On, Waraporn | ||||||||||
| PMID: | 27107220 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2016 Jun 7;7(23):34617-29. | ||||||||||
| Title: | FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression. | ||||||||||
| Author: | Wang, Wei|Zhan, Ming|Li, Qi|Chen, Wei|Chu, Huiling|Huang, Qihong|Hou, Zhaoyuan|Man, Mohan|Wang, Jian | ||||||||||
| PMID: | 27127878 | ||||||||||
| 23. | |||||||||||
| Journal: | Int J Oncol. 2016 Jul;49(1):197-206. | ||||||||||
| Title: | Leptin promotes proliferation and metastasis of human gallbladder cancer through OB-Rb leptin receptor. | ||||||||||
| Author: | Zou, Hao|Liu, Yunxia|Wei, Dong|Wang, Tao|Wang, Kun|Huang, Songquan|Liu, Lixin|Li, Yuehua|Ge, Jiayun|Li, Xiao|Zhu, Hong|Wang, Lianmin|Zhao, Songling|Zhang, Xiaowen|Wang, Lin | ||||||||||
| PMID: | 27211817 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Res. 2016 Jul 15;76(14):4124-35. | ||||||||||
| Title: | FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. | ||||||||||
| Author: | Yang, Xuguang|Lin, Yuli|Shi, Yinghong|Li, Bingji|Liu, Weiren|Yin, Wei|Dang, Yongjun|Chu, Yiwei|Fan, Jia|He, Rui | ||||||||||
| PMID: | 27216177 | ||||||||||
| 25. | |||||||||||
| Journal: | Expert Opin Ther Targets. 2017 May;21(5):485-498. | ||||||||||
| Title: | Signaling pathways as therapeutic targets in biliary tract cancer. | ||||||||||
| Author: | Yang, Jennifer|Farren, Matthew R|Ahn, Daniel|Bekaii-Saab, Tanios|Lesinski, Gregory B | ||||||||||
| PMID: | 28282502 | ||||||||||
| 26. | |||||||||||
| Journal: | Drug Des Devel Ther. 2017 Jun 15;11:1753-1766. | ||||||||||
| Title: | Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkappaB pathways in cholangiocarcinoma cells. | ||||||||||
| Author: | Ke, Fayong|Wang, Zheng|Song, Xiaoling|Ma, Qiang|Hu, Yunping|Jiang, Lin|Zhang, Yijian|Liu, Yingbin|Zhang, Yong|Gong, Wei | ||||||||||
| PMID: | 28670110 | ||||||||||
| 27. | |||||||||||
| Journal: | J Biol Regul Homeost Agents. 2017 Jan-Mar;31(1):51-58. | ||||||||||
| Title: | JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling. | ||||||||||
| Author: | Fu, L X|Lian, Q W|Pan, J D|Xu, Z L|Zhou, T M|Ye, B | ||||||||||
| PMID: | 28337870 | ||||||||||
| 28. | |||||||||||
| Journal: | Mol Cancer Ther. 2017 Jun;16(6):1145-1154. | ||||||||||
| Title: | Resistance Mechanism against Trastuzumab in HER2-Positive Cancer Cells and Its Negation by Src Inhibition. | ||||||||||
| Author: | Jin, Mei Hua|Nam, Ah-Rong|Park, Ji Eun|Bang, Ju-Hee|Bang, Yung-Jue|Oh, Do-Youn | ||||||||||
| PMID: | 28223426 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 31;8(5):7710-7721. | ||||||||||
| Title: | STAT3 overexpression promotes metastasis in intrahepatic cholangiocarcinoma and correlates negatively with surgical outcome. | ||||||||||
| Author: | Yang, Xin-Wei|Li, Liang|Hou, Guo-Jun|Yan, Xin-Zhou|Xu, Qin-Guo|Chen, Lei|Zhang, Bao-Hua|Shen, Feng | ||||||||||
| PMID: | 28032598 | ||||||||||
| 30. | |||||||||||
| Journal: | Asia Pac J Clin Oncol. 2018 Jun;14(3):134-140. | ||||||||||
| Title: | Molecular targets for the therapy of cancer associated with metabolic syndrome (transcription and growth factors). | ||||||||||
| Author: | Yunusova, Natalia V|Kondakova, Irina V|Kolomiets, Larisa A|Afanas'ev, Sergey G|Chernyshova, Alena L|Kudryavtsev, Igor V|Tsydenova, Anastasia A | ||||||||||
| PMID: | 29115033 | ||||||||||
| 31. | |||||||||||
| Journal: | Exp Ther Med. 2018 Jun;15(6):4995-5000. | ||||||||||
| Title: | Blocking of the EGFR-STAT3 signaling pathway through afatinib treatment inhibited the intrahepatic cholangiocarcinoma. | ||||||||||
| Author: | Zhang, Changhe|Xu, Hong|Zhou, Zhenping|Tian, Ye|Cao, Xiaofei|Cheng, Guochang|Liu, Qinghong | ||||||||||
| PMID: | 29805522 | ||||||||||
| 32. | |||||||||||
| Journal: | Pharmazie. 2018 Jul 1;73(7):413-417. | ||||||||||
| Title: | Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells. | ||||||||||
| Author: | Duan, Yi-Tao|Yang, Xiao-Ang|Fang, Lian-Ying|Wang, Jin-Han|Liu, Qiang | ||||||||||
| PMID: | 30001777 | ||||||||||
| 33. | |||||||||||
| Journal: | Int J Oncol. 2018 Sep;53(3):1215-1226. | ||||||||||
| Title: | Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy. | ||||||||||
| Author: | Hu, Ming-Tai|Wang, Jing-Han|Yu, Yong|Liu, Chen|Li, Bin|Cheng, Qing-Bao|Jiang, Xiao-Qing | ||||||||||
| PMID: | 30015925 | ||||||||||
| 34. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2018 Aug 7;37(1):186. | ||||||||||
| Title: | Long noncoding RNA HEGBC promotes tumorigenesis and metastasis of gallbladder cancer via forming a positive feedback loop with IL-11/STAT3 signaling pathway. | ||||||||||
| Author: | Yang, Liang|Gao, Qingxiang|Wu, Xiaoxiong|Feng, Feiling|Xu, Kaiyun | ||||||||||
| PMID: | 30086773 | ||||||||||
| 35. | |||||||||||
| Journal: | J Cancer Res Ther. 2018 Sep;14(Supplement):S758-S760. | ||||||||||
| Title: | Clinical significance of interleukin-6 in diagnosis of lung, oral, esophageal, and gall bladder carcinomas. | ||||||||||
| Author: | Vinocha, Anjali|Grover, Rajesh K|Deepak, Rani | ||||||||||
| PMID: | 30249899 | ||||||||||