Primary Site >> Biliary tract Cancer
Gene >> STAT3
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Ref: Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells. PMID: 16317687 |
Ref: Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. PMID: 19821497 |
Ref: Treatment of biliary tract cancer with NVP-AEW541: mechanisms of action and resistance. PMID: 20066734 Ref: Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. PMID: 20545696 |
Ref: Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells. PMID: 21331764 |
Ref: Hepatitis B virus X (HBx) induces tumorigenicity of hepatic progenitor cells in 3,5-diethoxycarbonyl-1,4-dihydrocollidine-treated HBx transgenic mice. PMID: 21932402 |
Ref: Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma. PMID: 22875246 Ref: Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes. PMID: 23295441 Ref: Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies. PMID: 23318457 Ref: [Molecular mechanism of gamma-aminobutyric acid inhibitory on the growth of cholangiocarcinoma QBC939 cell line]. PMID: 23859331 |
Ref: Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma. PMID: 24037855 Ref: Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway. PMID: 24038588 Ref: Luteolin arrests cell cycling, induces apoptosis and inhibits the JAK/STAT3 pathway in human cholangiocarcinoma cells. PMID: 24998588 Ref: Differentiation therapy: sesamin as an effective agent in targeting cancer stem-like side population cells of human gallbladder carcinoma. PMID: 25038821 Ref: STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression. PMID: 25044480 Ref: miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator. PMID: 25239565 Ref: FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling. PMID: 25344679 |
Ref: Enhanced expression of suppresser of cytokine signaling 3 inhibits the IL-6-induced epithelial-to-mesenchymal transition and cholangiocarcinoma cell metastasis. PMID: 25744243 Ref: Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats. PMID: 26028817 |
Ref: Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines. PMID: 26935541 Ref: Anoikis-resistant cholangiocarcinoma cells display aggressive characteristics and increase STAT3 activation. PMID: 27107220 Ref: FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression. PMID: 27127878 Ref: Leptin promotes proliferation and metastasis of human gallbladder cancer through OB-Rb leptin receptor. PMID: 27211817 Ref: FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. PMID: 27216177 |
Ref: STAT3 overexpression promotes metastasis in intrahepatic cholangiocarcinoma and correlates negatively with surgical outcome. PMID: 28032598 Ref: Resistance Mechanism against Trastuzumab in HER2-Positive Cancer Cells and Its Negation by Src Inhibition. PMID: 28223426 Ref: Signaling pathways as therapeutic targets in biliary tract cancer. PMID: 28282502 Ref: JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling. PMID: 28337870 Ref: Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkappaB pathways in cholangiocarcinoma cells. PMID: 28670110 |
Ref: Molecular targets for the therapy of cancer associated with metabolic syndrome (transcription and growth factors). PMID: 29115033 Ref: Blocking of the EGFR-STAT3 signaling pathway through afatinib treatment inhibited the intrahepatic cholangiocarcinoma. PMID: 29805522 Ref: Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells. PMID: 30001777 Ref: Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy. PMID: 30015925 Ref: Long noncoding RNA HEGBC promotes tumorigenesis and metastasis of gallbladder cancer via forming a positive feedback loop with IL-11/STAT3 signaling pathway. PMID: 30086773 Ref: Clinical significance of interleukin-6 in diagnosis of lung, oral, esophageal, and gall bladder carcinomas. PMID: 30249899 |