Primary Site >> Pancreatic Cancer
Gene >> STAT1
| 1. | |||||||||||
| Journal: | Ann Surg Oncol. 1998 Oct-Nov;5(7):642-9. | ||||||||||
| Title: | Interferon-mediated activation of the STAT signaling pathway in a human carcinoid tumor. | ||||||||||
| Author: | Wang, S|Tyring, S K|Townsend, C M Jr|Evers, B M | ||||||||||
| PMID: | 9831114 | ||||||||||
| 2. | |||||||||||
| Journal: | J Leukoc Biol. 2004 Aug;76(2):314-21. | ||||||||||
| Title: | The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain. | ||||||||||
| Author: | Donnelly, Raymond P|Sheikh, Faruk|Kotenko, Sergei V|Dickensheets, Harold | ||||||||||
| PMID: | 15123776 | ||||||||||
| 3. | |||||||||||
| Journal: | Oncogene. 2005 Jan 6;24(1):199-211. | ||||||||||
| Title: | Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway. | ||||||||||
| Author: | Missiaglia, Edoardo|Donadelli, Massimo|Palmieri, Marta|Crnogorac-Jurcevic, Tatjana|Scarpa, Aldo|Lemoine, Nicholas R | ||||||||||
| PMID: | 15637593 | ||||||||||
| 4. | |||||||||||
| Journal: | Cell Signal. 2007 Apr;19(4):782-90. Epub 2006 Nov 20. | ||||||||||
| Title: | Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression. | ||||||||||
| Author: | Fitzner, Brit|Brock, Peter|Nechutova, Hana|Glass, Anne|Karopka, Thomas|Koczan, Dirk|Thiesen, Hans-Jurgen|Sparmann, Gisela|Emmrich, Jorg|Liebe, Stefan|Jaster, Robert | ||||||||||
| PMID: | 17116388 | ||||||||||
| 5. | |||||||||||
| Journal: | Int J Cancer. 2008 Oct 15;123(8):1751-60. | ||||||||||
| Title: | Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases. | ||||||||||
| Author: | Muerkoster, Susanne Sebens|Werbing, Veronika|Koch, Dorothee|Sipos, Bence|Ammerpohl, Ole|Kalthoff, Holger|Tsao, Ming-Sound|Folsch, Ulrich R|Schafer, Heiner | ||||||||||
| PMID: | 18649362 | ||||||||||
| 6. | |||||||||||
| Journal: | Invest New Drugs. 2009 Dec;27(6):491-502. | ||||||||||
| Title: | The fungal secondary metabolite trichodimerol inhibits TGF-beta dependent cellular effects and tube formation of MDA-MB-231 cells. | ||||||||||
| Author: | Serwe, Annegret|Anke, Timm|Erkel, Gerhard | ||||||||||
| PMID: | 19009233 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Biol Rep. 2010 Jul;37(6):2797-802. | ||||||||||
| Title: | Transcriptional regulation of human mucin gene MUC4 in pancreatic cancer cells. | ||||||||||
| Author: | Zhang, Jingjing|Zhang, Xiongfei|Zhu, Yi|Chen, Zheng|Xu, Zekuan|Miao, Yi | ||||||||||
| PMID: | 19757157 | ||||||||||
| 8. | |||||||||||
| Journal: | Mol Cancer. 2011 Feb 10;10(1):13. | ||||||||||
| Title: | Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach. | ||||||||||
| Author: | Lange, Falko|Rateitschak, Katja|Fitzner, Brit|Pohland, Ralf|Wolkenhauer, Olaf|Jaster, Robert | ||||||||||
| PMID: | 21310022 | ||||||||||
| 9. | |||||||||||
| Journal: | J Biol Chem. 2011 Apr 8;286(14):12245-56. | ||||||||||
| Title: | Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines. | ||||||||||
| Author: | Wu, Yongzhong|Antony, Smitha|Juhasz, Agnes|Lu, Jiamo|Ge, Yun|Jiang, Guojian|Roy, Krishnendu|Doroshow, James H | ||||||||||
| PMID: | 21321110 | ||||||||||
| 10. | |||||||||||
| Journal: | J Immunol. 2011 Jun 15;186(12):6933-44. | ||||||||||
| Title: | Novel TGF-beta antagonist inhibits tumor growth and angiogenesis by inducing IL-2 receptor-driven STAT1 activation. | ||||||||||
| Author: | Penafuerte, Claudia|Bautista-Lopez, Norma|Bouchentouf, Manaf|Birman, Elena|Forner, Kathy|Galipeau, Jacques | ||||||||||
| PMID: | 21551368 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer. 2012 Apr 26;11:24. | ||||||||||
| Title: | Nicotine, IFN-gamma and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades. | ||||||||||
| Author: | Kunigal, Sateesh|Ponnusamy, Moorthy P|Momi, Navneet|Batra, Surinder K|Chellappan, Srikumar P | ||||||||||
| PMID: | 22537161 | ||||||||||
| 12. | |||||||||||
| Journal: | IET Syst Biol. 2012 Jun;6(3):73-85. | ||||||||||
| Title: | Mathematical modelling unravels regulatory mechanisms of interferon-gamma-induced STAT1 serine-phosphorylation and MUC4 expression in pancreatic cancer cells. | ||||||||||
| Author: | Kossow, C|Jose, D|Jaster, R|Wolkenhauer, O|Rateitschak, K | ||||||||||
| PMID: | 22757586 | ||||||||||
| 13. | |||||||||||
| Journal: | Gut Liver. 2012 Oct;6(4):417-22. | ||||||||||
| Title: | Role of janus kinase/signal transducers and activators of transcription in the pathogenesis of pancreatitis and pancreatic cancer. | ||||||||||
| Author: | Yu, Ji Hoon|Kim, Hyeyoung | ||||||||||
| PMID: | 23170143 | ||||||||||
| 14. | |||||||||||
| Journal: | PLoS One. 2012;7(11):e47520. | ||||||||||
| Title: | Pan-Bcl-2 inhibitor AT-101 enhances tumor cell killing by EGFR targeted T cells. | ||||||||||
| Author: | Thakur, Archana|Lum, Lawrence G|Schalk, Dana|Azmi, Asfar|Banerjee, Sanjeev|Sarkar, Fazlul H|Mohommad, Ramzi | ||||||||||
| PMID: | 23185240 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS Comput Biol. 2012;8(12):e1002815. | ||||||||||
| Title: | Parameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cells. | ||||||||||
| Author: | Rateitschak, Katja|Winter, Felix|Lange, Falko|Jaster, Robert|Wolkenhauer, Olaf | ||||||||||
| PMID: | 23284277 | ||||||||||
| 16. | |||||||||||
| Journal: | J Mol Biochem. 2013 Feb 20;2(1):18-26. | ||||||||||
| Title: | STAT3 Inhibition Induces Apoptosis in Cancer Cells Independent of STAT1 or STAT2. | ||||||||||
| Author: | Shodeinde, Adetola|Ginjupalli, Kalyani|Lewis, H Dan|Riaz, Sheraz|Barton, Beverly E | ||||||||||
| PMID: | 25364701 | ||||||||||
| 17. | |||||||||||
| Journal: | Cell Signal. 2013 Dec;25(12):2587-603. | ||||||||||
| Title: | A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer. | ||||||||||
| Author: | Gilmour, Alanna M|Abdulkhalek, Samar|Cheng, Timothy S W|Alghamdi, Farah|Jayanth, Preethi|O'Shea, Leah K|Geen, Olivia|Arvizu, Luis A|Szewczuk, Myron R | ||||||||||
| PMID: | 23993964 | ||||||||||
| 18. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2013 Feb;17(3):311-7. | ||||||||||
| Title: | Expression profiles analysis of pancreatic cancer. | ||||||||||
| Author: | Yang, D|Zhu, Z|Wang, W|Shen, P|Wei, Z|Wang, C|Cai, Q | ||||||||||
| PMID: | 23426533 | ||||||||||
| 19. | |||||||||||
| Journal: | J Immunol. 2013 Feb 15;190(4):1859-72. | ||||||||||
| Title: | Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-gamma and lipopolysaccharide in human pancreatic cancer cell lines. | ||||||||||
| Author: | Wu, Yongzhong|Lu, Jiamo|Antony, Smitha|Juhasz, Agnes|Liu, Han|Jiang, Guojian|Meitzler, Jennifer L|Hollingshead, Melinda|Haines, Diana C|Butcher, Donna|Roy, Krishnendu|Doroshow, James H | ||||||||||
| PMID: | 23296709 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Res. 2013 Jan 15;73(2):885-96. | ||||||||||
| Title: | Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma. | ||||||||||
| Author: | Shakya, Reena|Gonda, Tamas|Quante, Michael|Salas, Martha|Kim, Samuel|Brooks, Jenna|Hirsch, Steffen|Davies, Justine|Cullo, Angelica|Olive, Kenneth|Wang, Timothy C|Szabolcs, Matthias|Tycko, Benjamin|Ludwig, Thomas | ||||||||||
| PMID: | 23204224 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2013 May 15;73(10):3007-18. | ||||||||||
| Title: | Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner. | ||||||||||
| Author: | Mace, Thomas A|Ameen, Zeenath|Collins, Amy|Wojcik, Sylwia|Mair, Markus|Young, Gregory S|Fuchs, James R|Eubank, Tim D|Frankel, Wendy L|Bekaii-Saab, Tanios|Bloomston, Mark|Lesinski, Gregory B | ||||||||||
| PMID: | 23514705 | ||||||||||
| 22. | |||||||||||
| Journal: | Pancreas. 2014 May;43(4):619-23. | ||||||||||
| Title: | Differential expression of STAT1 and p21 proteins predicts pancreatic cancer progression and prognosis. | ||||||||||
| Author: | Sun, Yu|Yang, Shaoshi|Sun, Ning|Chen, Jianqiu | ||||||||||
| PMID: | 24658320 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncotarget. 2015 Feb 20;6(5):3306-18. | ||||||||||
| Title: | Overexpression of IFN-induced protein with tetratricopeptide repeats 3 (IFIT3) in pancreatic cancer: cellular "pseudoinflammation" contributing to an aggressive phenotype. | ||||||||||
| Author: | Niess, Hanno|Camaj, Peter|Mair, Ruth|Renner, Andrea|Zhao, Yue|Jackel, Carsten|Nelson, Peter J|Jauch, Karl-Walter|Bruns, Christiane J | ||||||||||
| PMID: | 25650658 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncotarget. 2015 Mar 10;6(7):5164-81. | ||||||||||
| Title: | Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer. | ||||||||||
| Author: | Seshacharyulu, Parthasarathy|Ponnusamy, Moorthy P|Rachagani, Satyanarayana|Lakshmanan, Imayavaramban|Haridas, Dhanya|Yan, Ying|Ganti, Apar K|Batra, Surinder K | ||||||||||
| PMID: | 25686822 | ||||||||||
| 25. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2015 Apr 3;459(2):313-318. | ||||||||||
| Title: | Pancreatic adenocarcinoma upregulated factor (PAUF) confers resistance to pancreatic cancer cells against oncolytic parvovirus H-1 infection through IFNA receptor-mediated signaling. | ||||||||||
| Author: | Kaowinn, Sirichat|Cho, Il-Rae|Moon, Jeong|Jun, Seung Won|Kim, Chang Seok|Kang, Ho Young|Kim, Manbok|Koh, Sang Seok|Chung, Young-Hwa | ||||||||||
| PMID: | 25727013 | ||||||||||
| 26. | |||||||||||
| Journal: | Virology. 2015 Nov;485:340-54. | ||||||||||
| Title: | Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1. | ||||||||||
| Author: | Cataldi, Marcela|Shah, Nirav R|Felt, Sebastien A|Grdzelishvili, Valery Z | ||||||||||
| PMID: | 26331681 | ||||||||||
| 27. | |||||||||||
| Journal: | Nat Genet. 2016 Jul;48(7):747-57. | ||||||||||
| Title: | Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation. | ||||||||||
| Author: | Zheng, Jian|Huang, Xudong|Tan, Wen|Yu, Dianke|Du, Zhongli|Chang, Jiang|Wei, Lixuan|Han, Yaling|Wang, Chengfeng|Che, Xu|Zhou, Yifeng|Miao, Xiaoping|Jiang, Guoliang|Yu, Xianjun|Yang, Xianghong|Cao, Guangwen|Zuo, Chaohui|Li, Zhaoshen|Wang, Chunyou|Cheung, Si | ||||||||||
| PMID: | 27213290 | ||||||||||
| 28. | |||||||||||
| Journal: | Mol Cancer Ther. 2016 Nov;15(11):2609-2619. | ||||||||||
| Title: | Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy. | ||||||||||
| Author: | Wu, Xiaojuan|Cao, Yang|Xiao, Hui|Li, Chenglong|Lin, Jiayuh | ||||||||||
| PMID: | 27535971 | ||||||||||
| 29. | |||||||||||
| Journal: | Clin Cancer Res. 2017 Jan 15;23(2):489-502. | ||||||||||
| Title: | IL-21 Enhances Natural Killer Cell Response to Cetuximab-Coated Pancreatic Tumor Cells. | ||||||||||
| Author: | McMichael, Elizabeth L|Jaime-Ramirez, Alena Cristina|Guenterberg, Kristan D|Luedke, Eric|Atwal, Lakhvir S|Campbell, Amanda R|Hu, Zhiwei|Tatum, Armika S|Kondadasula, Sri Vidya|Mo, Xiaokui|Tridandapani, Susheela|Bloomston, Mark|Ellison, E Christopher|Willia | ||||||||||
| PMID: | 27435400 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncol Rep. 2017 Mar;37(3):1545-1554. | ||||||||||
| Title: | The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines. | ||||||||||
| Author: | Doi, Toshifumi|Ishikawa, Takeshi|Okayama, Tetsuya|Oka, Kaname|Mizushima, Katsura|Yasuda, Tomoyo|Sakamoto, Naoyuki|Katada, Kazuhiro|Kamada, Kazuhiro|Uchiyama, Kazuhiko|Handa, Osamu|Takagi, Tomohisa|Naito, Yuji|Itoh, Yoshito | ||||||||||
| PMID: | 28112370 | ||||||||||
| 31. | |||||||||||
| Journal: | Pancreatology. 2017 Jul - Aug;17(4):635-641. | ||||||||||
| Title: | Tumour-associated macrophages activate migration and STAT3 in pancreatic ductal adenocarcinoma cells in co-cultures. | ||||||||||
| Author: | Salmiheimo, Aino|Mustonen, Harri|Vainionpaa, Sanna|Shen, Zhanlong|Kemppainen, Esko|Puolakkainen, Pauli|Seppanen, Hanna | ||||||||||
| PMID: | 28476581 | ||||||||||
| 32. | |||||||||||
| Journal: | Oncoimmunology. 2017 Apr 28;6(6):e1321185. | ||||||||||
| Title: | Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFNgamma signaling. | ||||||||||
| Author: | Penafuerte, Claudia|Feldhammer, Matthew|Mills, John R|Vinette, Valerie|Pike, Kelly A|Hall, Anita|Migon, Eva|Karsenty, Gerard|Pelletier, Jerry|Zogopoulos, George|Tremblay, Michel L | ||||||||||
| PMID: | 28680757 | ||||||||||
| 33. | |||||||||||
| Journal: | Sci Rep. 2017 Nov 13;7(1):15424. | ||||||||||
| Title: | Nitric oxide mediated inhibition of antigen presentation from DCs to CD4(+) T cells in cancer and measurement of STAT1 nitration. | ||||||||||
| Author: | Markowitz, Joseph|Wang, Jiang|Vangundy, Zach|You, Jia|Yildiz, Vedat|Yu, Lianbo|Foote, Isaac P|Branson, Owen E|Stiff, Andrew R|Brooks, Taylor R|Biesiadecki, Brandon|Olencki, Thomas|Tridandapani, Susheela|Freitas, Michael A|Papenfuss, Tracey|Phelps, Mitch A | ||||||||||
| PMID: | 29133913 | ||||||||||
| 34. | |||||||||||
| Journal: | Gastroenterology. 2018 Feb;154(3):675-688. | ||||||||||
| Title: | Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice. | ||||||||||
| Author: | Huang, Chongbiao|Li, Zengxun|Li, Na|Li, Yang|Chang, Antao|Zhao, Tiansuo|Wang, Xiuchao|Wang, Hongwei|Gao, Song|Yang, Shengyu|Hao, Jihui|Ren, He | ||||||||||
| PMID: | 28989066 | ||||||||||
| 35. | |||||||||||
| Journal: | Cancer Manag Res. 2018 Mar 23;10:565-581. | ||||||||||
| Title: | L61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway. | ||||||||||
| Author: | Bai, Encheng|Yang, Lehe|Xiang, Youqun|Hu, Wanle|Li, Caleb|Lin, Jiayuh|Dai, Xuanxuan|Liang, Guang|Jin, Rong|Zhao, Chengguang | ||||||||||
| PMID: | 29606890 | ||||||||||