Primary Site >> Colorectal Cancer
Gene >> STAT1
| 1. | |||||||||||
| Journal: | J Immunol. 1996 Apr 15;156(8):2972-8. | ||||||||||
| Title: | IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. | ||||||||||
| Author: | Murata, T|Noguchi, P D|Puri, R K | ||||||||||
| PMID: | 8609418 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 1998 Feb 20;273(8):4642-6. | ||||||||||
| Title: | Transcriptional silencing of perlecan gene expression by interferon-gamma. | ||||||||||
| Author: | Sharma, B|Iozzo, R V | ||||||||||
| PMID: | 9468523 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2000 Apr 7;275(14):10212-7. | ||||||||||
| Title: | Interleukin-4 mediates cell growth inhibition through activation of Stat1. | ||||||||||
| Author: | Chang, T L|Peng, X|Fu, X Y | ||||||||||
| PMID: | 10744706 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2000 Jun 15;60(12):3200-6. | ||||||||||
| Title: | Regrowth of 5-fluorouracil-treated human colon cancer cells is prevented by the combination of interferon gamma, indomethacin, and phenylbutyrate. | ||||||||||
| Author: | Huang, Y|Horvath, C M|Waxman, S | ||||||||||
| PMID: | 10866311 | ||||||||||
| 5. | |||||||||||
| Journal: | Exp Cell Res. 2001 Jan 15;262(2):154-69. | ||||||||||
| Title: | p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma. | ||||||||||
| Author: | Meng, R D|El-Deiry, W S | ||||||||||
| PMID: | 11139340 | ||||||||||
| 6. | |||||||||||
| Journal: | Exp Cell Res. 2002 Nov 15;281(1):19-27. | ||||||||||
| Title: | STAT1 is required for IFN-gamma-mediated gut-enriched Kruppel-like factor expression. | ||||||||||
| Author: | Chen, Zhi Y|Shie, Jue Lon|Tseng, Chi Chuan | ||||||||||
| PMID: | 12441126 | ||||||||||
| 7. | |||||||||||
| Journal: | J Biol Chem. 2003 Nov 21;278(47):46278-87. Epub 2003 Sep 12. | ||||||||||
| Title: | Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression. | ||||||||||
| Author: | Klampfer, Lidija|Huang, Jie|Corner, Georgia|Mariadason, John|Arango, Diego|Sasazuki, Takehiko|Shirasawa, Senji|Augenlicht, Leonard | ||||||||||
| PMID: | 12972432 | ||||||||||
| 8. | |||||||||||
| Journal: | J Biol Chem. 2004 Jul 16;279(29):30358-68. Epub 2004 May 3. | ||||||||||
| Title: | Requirement of histone deacetylase activity for signaling by STAT1. | ||||||||||
| Author: | Klampfer, Lidija|Huang, Jie|Swaby, Laurie-Anne|Augenlicht, Leonard | ||||||||||
| PMID: | 15123634 | ||||||||||
| 9. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2004 Jul 30;320(3):875-9. | ||||||||||
| Title: | NSAIDs activate PTEN and other phosphatases in human colon cancer cells: novel mechanism for chemopreventive action of NSAIDs. | ||||||||||
| Author: | Chu, Eric C|Chai, Jianyuan|Tarnawski, Andrzej S | ||||||||||
| PMID: | 15240129 | ||||||||||
| 10. | |||||||||||
| Journal: | Carcinogenesis. 2004 Nov;25(11):2247-55. | ||||||||||
| Title: | IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor. | ||||||||||
| Author: | Yuan, Hanna|Liddle, Forrester J|Mahajan, Sudipta|Frank, David A | ||||||||||
| PMID: | 15284182 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Pharmacol. 2005 Nov;68(5):1203-13. Epub 2005 Aug 2. | ||||||||||
| Title: | 15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal tra | ||||||||||
| Author: | Chen, Zhi Yi|Tseng, Chi-Chuan | ||||||||||
| PMID: | 16077033 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Res. 2005 Oct 1;65(19):8951-60. | ||||||||||
| Title: | Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer. | ||||||||||
| Author: | McDermott, Ultan|Longley, Daniel B|Galligan, Leeona|Allen, Wendy|Wilson, Timothy|Johnston, Patrick G | ||||||||||
| PMID: | 16204068 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Sci. 2006 Jan;97(1):57-63. | ||||||||||
| Title: | Strong HLA-DR antigen expression on cancer cells relates to better prognosis of colorectal cancer patients: Possible involvement of c-myc suppression by interferon-gamma in situ. | ||||||||||
| Author: | Matsushita, Kazuyuki|Takenouchi, Toshinao|Shimada, Hideaki|Tomonaga, Takeshi|Hayashi, Hideki|Shioya, Ayumi|Komatsu, Aki|Matsubara, Hisahiro|Ochiai, Takenori | ||||||||||
| PMID: | 16367922 | ||||||||||
| 14. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2006 Nov 15;217(1):35-42. Epub 2006 Jul 14. | ||||||||||
| Title: | Paeonol attenuates TNBS-induced colitis by inhibiting NF-kappaB and STAT1 transactivation. | ||||||||||
| Author: | Ishiguro, Kazuhiro|Ando, Takafumi|Maeda, Osamu|Hasegawa, Motofusa|Kadomatsu, Kenji|Ohmiya, Naoki|Niwa, Yasumasa|Xavier, Ramnik|Goto, Hidemi | ||||||||||
| PMID: | 16928387 | ||||||||||
| 15. | |||||||||||
| Journal: | J Exp Med. 2006 Jun 12;203(6):1391-7. Epub 2006 May 22. | ||||||||||
| Title: | IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice. | ||||||||||
| Author: | Hanada, Toshikatsu|Kobayashi, Takashi|Chinen, Takatoshi|Saeki, Kazuko|Takaki, Hiromi|Koga, Keiko|Minoda, Yasumasa|Sanada, Takahito|Yoshioka, Tomoko|Mimata, Hiromitsu|Kato, Seiya|Yoshimura, Akihiko | ||||||||||
| PMID: | 16717119 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncogene. 2007 Mar 29;26(14):2071-81. Epub 2006 Oct 2. | ||||||||||
| Title: | STAT1-independent inhibition of cyclooxygenase-2 expression by IFNgamma; a common pathway of IFNgamma-mediated gene repression but not gene activation. | ||||||||||
| Author: | Klampfer, L|Huang, J|Kaler, P|Sasazuki, T|Shirasawa, S|Augenlicht, L | ||||||||||
| PMID: | 17016440 | ||||||||||
| 17. | |||||||||||
| Journal: | J Biol Chem. 2007 Mar 30;282(13):9797-804. Epub 2007 Jan 24. | ||||||||||
| Title: | Essential role of the JAK/STAT1 signaling pathway in the expression of inducible nitric-oxide synthase in intestinal epithelial cells and its regulation by butyrate. | ||||||||||
| Author: | Stempelj, Mateja|Kedinger, Michele|Augenlicht, Leonard|Klampfer, Lidija | ||||||||||
| PMID: | 17251186 | ||||||||||
| 18. | |||||||||||
| Journal: | J Biol Chem. 2007 Jun 1;282(22):16006-15. Epub 2007 Apr 16. | ||||||||||
| Title: | The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells. | ||||||||||
| Author: | Ziesche, Elisabeth|Bachmann, Malte|Kleinert, Hartmut|Pfeilschifter, Josef|Muhl, Heiko | ||||||||||
| PMID: | 17438334 | ||||||||||
| 19. | |||||||||||
| Journal: | Gut. 2007 Sep;56(9):1257-65. Epub 2007 Apr 20. | ||||||||||
| Title: | Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease. | ||||||||||
| Author: | Dambacher, Julia|Beigel, Florian|Seiderer, Julia|Haller, Dirk|Goke, Burkhard|Auernhammer, Christoph J|Brand, Stephan | ||||||||||
| PMID: | 17449633 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Genomics Proteomics. 2007 Mar-Apr;4(2):93-7. | ||||||||||
| Title: | Diallyl disulfide induced signal transducer and activator of transcription 1 expression in human colon cancer colo 205 cells using differential display RT-PCR. | ||||||||||
| Author: | Lu, Hsu-Fung|Yang, Jai-Sing|Lin, Yuh-Tzy|Tan, Tzu-Wei|Ip, Siu-Wan|Li, Yu-Ching|Tsou, Mei-Fen|Chung, Jing-Gung | ||||||||||
| PMID: | 17804871 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2007 Sep 15;67(18):8477-85. | ||||||||||
| Title: | Histone deacetylase inhibitors induce cell death selectively in cells that harbor activated kRasV12: The role of signal transducers and activators of transcription 1 and p21. | ||||||||||
| Author: | Klampfer, Lidija|Huang, Jie|Shirasawa, Senji|Sasazuki, Takehiko|Augenlicht, Leonard | ||||||||||
| PMID: | 17875686 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Lett. 2008 Feb 18;260(1-2):62-71. Epub 2007 Nov 26. | ||||||||||
| Title: | Regulation of XAF1 expression in human colon cancer cell by interferon beta: activation by the transcription regulator STAT1. | ||||||||||
| Author: | Sun, Yunwei|Qiao, Liang|Xia, Harry Hua-Xiang|Lin, Marie C M|Zou, Bing|Yuan, Yaozong|Zhu, Senlin|Gu, Qing|Cheung, Ting Kin|Kung, Hsiang Fu|Yuen, Man Fung|Chan, Annie Oo|Wong, Benjamin C Y | ||||||||||
| PMID: | 18035482 | ||||||||||
| 23. | |||||||||||
| Journal: | PLoS Med. 2008 May 20;5(5):e94. | ||||||||||
| Title: | A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA. | ||||||||||
| Author: | Masuda, Kiyoshi|Teshima-Kondo, Shigetada|Mukaijo, Mina|Yamagishi, Naoko|Nishikawa, Yoshiko|Nishida, Kensei|Kawai, Tomoko|Rokutan, Kazuhito | ||||||||||
| PMID: | 18494554 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Cancer. 2008 Apr 1;122(7):1567-72. | ||||||||||
| Title: | HPP1-mediated tumor suppression requires activation of STAT1 pathways. | ||||||||||
| Author: | Elahi, Abul|Zhang, Li|Yeatman, Timothy J|Gery, Sigal|Sebti, Said|Shibata, David | ||||||||||
| PMID: | 18059030 | ||||||||||
| 25. | |||||||||||
| Journal: | Front Biosci. 2008 Jan 1;13:2888-99. | ||||||||||
| Title: | The role of signal transducers and activators of transcription in colon cancer. | ||||||||||
| Author: | Klampfer, Lidija | ||||||||||
| PMID: | 17981761 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Carcinog. 2008 Feb;47(2):75-9. | ||||||||||
| Title: | STAT1 expression is not required for polyp formation in Min mice. | ||||||||||
| Author: | Liddle, Forrester J|Frank, David A | ||||||||||
| PMID: | 17683066 | ||||||||||
| 27. | |||||||||||
| Journal: | J Cell Mol Med. 2009 Aug;13(8B):1987-94. | ||||||||||
| Title: | Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level. | ||||||||||
| Author: | Bachmann, Malte|Paulukat, Jens|Pfeilschifter, Josef|Muhl, Heiko | ||||||||||
| PMID: | 19046253 | ||||||||||
| 28. | |||||||||||
| Journal: | FEBS J. 2009 May;276(9):2505-15. | ||||||||||
| Title: | Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide--interference with interferon-gamma-STAT1-mediated killing. | ||||||||||
| Author: | Tadlaoui Hbibi, Ali|Laguillier, Christelle|Souissi, Ines|Lesage, Denis|Le Coquil, Stephanie|Cao, An|Metelev, Valeri|Baran-Marszak, Fanny|Fagard, Remi | ||||||||||
| PMID: | 19476491 | ||||||||||
| 29. | |||||||||||
| Journal: | Chem Biol Interact. 2009 Oct 30;181(3):440-6. | ||||||||||
| Title: | A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells. | ||||||||||
| Author: | Chen, Yu-Jen|Chang, Wei-Min|Liu, Yi-Wen|Lee, Chia-Yun|Jang, Yi-Hua|Kuo, Cheng-Deng|Liao, Hui-Fen | ||||||||||
| PMID: | 19616522 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncogene. 2009 Nov 5;28(44):3892-902. | ||||||||||
| Title: | Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: a crosstalk interrupted by vitamin D3. | ||||||||||
| Author: | Kaler, P|Augenlicht, L|Klampfer, L | ||||||||||
| PMID: | 19701245 | ||||||||||
| 31. | |||||||||||
| Journal: | J Immunol. 2010 Oct 15;185(8):4912-20. | ||||||||||
| Title: | IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. | ||||||||||
| Author: | Zaki, Mohammad Hasan|Vogel, Peter|Body-Malapel, Mathilde|Lamkanfi, Mohamed|Kanneganti, Thirumala-Devi | ||||||||||
| PMID: | 20855874 | ||||||||||
| 32. | |||||||||||
| Journal: | Mol Cancer. 2010 Aug 16;9:217. | ||||||||||
| Title: | A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells. | ||||||||||
| Author: | Lin, Li|Deangelis, Stephanie|Foust, Elizabeth|Fuchs, James|Li, Chenglong|Li, Pui-Kai|Schwartz, Eric B|Lesinski, Gregory B|Benson, Don|Lu, Jiagao|Hoyt, Dale|Lin, Jiayuh | ||||||||||
| PMID: | 20712901 | ||||||||||
| 33. | |||||||||||
| Journal: | Curr Med Chem. 2010;17(29):3303-8. | ||||||||||
| Title: | Anticancer properties of the IL-12 family--focus on colorectal cancer. | ||||||||||
| Author: | Engel, M A|Neurath, M F | ||||||||||
| PMID: | 20712574 | ||||||||||
| 34. | |||||||||||
| Journal: | Gut. 2010 Jul;59(7):926-33. | ||||||||||
| Title: | Intratumoral T cell infiltration, MHC class I and STAT1 as biomarkers of good prognosis in colorectal cancer. | ||||||||||
| Author: | Simpson, Jonathan A D|Al-Attar, Ahmad|Watson, Nicholas F S|Scholefield, John H|Ilyas, Mohammad|Durrant, Lindy G | ||||||||||
| PMID: | 20581241 | ||||||||||
| 35. | |||||||||||
| Journal: | Mol Cancer Res. 2010 May;8(5):798-805. | ||||||||||
| Title: | STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells. | ||||||||||
| Author: | Wang, Shuo|Raven, Jennifer F|Koromilas, Antonis E | ||||||||||
| PMID: | 20407011 | ||||||||||
| 36. | |||||||||||
| Journal: | PLoS One. 2010 Jan 21;5(1):e8836. | ||||||||||
| Title: | MicroRNA-145 targets YES and STAT1 in colon cancer cells. | ||||||||||
| Author: | Gregersen, Lea H|Jacobsen, Anders B|Frankel, Lisa B|Wen, Jiayu|Krogh, Anders|Lund, Anders H | ||||||||||
| PMID: | 20098684 | ||||||||||
| 37. | |||||||||||
| Journal: | Mol Genet Genomics. 2011 Oct;286(3-4):279-91. | ||||||||||
| Title: | Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns. | ||||||||||
| Author: | Bormann, Felix|Sers, Christine|Seliger, Barbara|Handke, Diana|Bergmann, Thomas|Seibt, Stephanie|Lehrach, Hans|Dahl, Andreas | ||||||||||
| PMID: | 21879293 | ||||||||||
| 38. | |||||||||||
| Journal: | Cancer Res. 2011 Nov 15;71(22):7010-20. | ||||||||||
| Title: | ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression. | ||||||||||
| Author: | Kim, Sun-Hee|Park, Yun-Yong|Kim, Sang-Wook|Lee, Ju-Seog|Wang, Dingzhi|DuBois, Raymond N | ||||||||||
| PMID: | 21937683 | ||||||||||
| 39. | |||||||||||
| Journal: | Mol Cancer. 2012 Mar 16;11:12. | ||||||||||
| Title: | A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line. | ||||||||||
| Author: | Souissi, Ines|Ladam, Patrick|Cognet, Jean A H|Le Coquil, Stephanie|Varin-Blank, Nadine|Baran-Marszak, Fanny|Metelev, Valeri|Fagard, Remi | ||||||||||
| PMID: | 22423663 | ||||||||||
| 40. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15;302(12):G1405-15. | ||||||||||
| Title: | Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. | ||||||||||
| Author: | Zimmerman, Mary A|Singh, Nagendra|Martin, Pamela M|Thangaraju, Muthusamy|Ganapathy, Vadivel|Waller, Jennifer L|Shi, Huidong|Robertson, Keith D|Munn, David H|Liu, Kebin | ||||||||||
| PMID: | 22517765 | ||||||||||
| 41. | |||||||||||
| Journal: | Eur J Immunol. 2012 Aug;42(8):2052-9. | ||||||||||
| Title: | Tumor-induced myeloid-derived suppressor cell function is independent of IFN-gamma and IL-4Ralpha. | ||||||||||
| Author: | Sinha, Pratima|Parker, Katherine H|Horn, Lucas|Ostrand-Rosenberg, Suzanne | ||||||||||
| PMID: | 22673957 | ||||||||||
| 42. | |||||||||||
| Journal: | Antiinflamm Antiallergy Agents Med Chem. 2012;11(3):221-9. | ||||||||||
| Title: | Interleukin-26, a highly cationic T-cell cytokine targeting epithelial cells. | ||||||||||
| Author: | Braum, Oliver|Pirzer, Heide|Fickenscher, Helmut | ||||||||||
| PMID: | 23106140 | ||||||||||
| 43. | |||||||||||
| Journal: | Oncol Lett. 2012 Sep;4(3):546-550. | ||||||||||
| Title: | (-)-Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells. | ||||||||||
| Author: | Ogawa, Kengo|Hara, Takeshi|Shimizu, Masahito|Nagano, Junji|Ohno, Tomohiko|Hoshi, Masato|Ito, Hiroyasu|Tsurumi, Hisashi|Saito, Kuniaki|Seishima, Mitsuru|Moriwaki, Hisataka | ||||||||||
| PMID: | 23741252 | ||||||||||
| 44. | |||||||||||
| Journal: | Mol Carcinog. 2013 Feb;52(2):155-66. | ||||||||||
| Title: | JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Kadlubar, Susan A|Bondurant, Kristina L|Wolff, Roger K | ||||||||||
| PMID: | 22121102 | ||||||||||
| 45. | |||||||||||
| Journal: | Front Oncol. 2013 Nov 25;3:288. | ||||||||||
| Title: | A Predictive Genetic Signature for Response to Fluoropyrimidine-Based Neoadjuvant Chemoradiation in Clinical Stage II and III Rectal Cancer. | ||||||||||
| Author: | Chan, Jason|Kinsella, Michael T|Willis, Joseph E|Hu, Huankai|Reynolds, Harry Jr|Delaney, Conor|McCulla, Andrea|Deharo, Steve|Ahdesmaki, Miika|Allen, Wendy Louise|Johnston, Patrick G|Kinsella, Timothy J | ||||||||||
| PMID: | 24324931 | ||||||||||
| 46. | |||||||||||
| Journal: | Int J Oncol. 2013 Oct;43(4):1111-6. | ||||||||||
| Title: | Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation. | ||||||||||
| Author: | Malilas, Waraporn|Koh, Sang Seok|Kim, Seokho|Srisuttee, Ratakorn|Cho, Il-Rae|Moon, Jeong|Yoo, Hwa-Seung|Oh, Sangtaek|Johnston, Randal N|Chung, Young-Hwa | ||||||||||
| PMID: | 23917355 | ||||||||||
| 47. | |||||||||||
| Journal: | Biochem Pharmacol. 2013 Feb 1;85(3):396-403. | ||||||||||
| Title: | IFNalpha converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets. | ||||||||||
| Author: | Bachmann, Malte|Ulziibat, Solongo|Hardle, Lorena|Pfeilschifter, Josef|Muhl, Heiko | ||||||||||
| PMID: | 23153456 | ||||||||||
| 48. | |||||||||||
| Journal: | Br J Cancer. 2013 Jul 9;109(1):138-46. | ||||||||||
| Title: | Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma. | ||||||||||
| Author: | Gordziel, C|Bratsch, J|Moriggl, R|Knosel, T|Friedrich, K | ||||||||||
| PMID: | 23756862 | ||||||||||
| 49. | |||||||||||
| Journal: | Front Oncol. 2014 Apr 30;4:88. | ||||||||||
| Title: | The Role of STAT1 for Crosstalk between Fibroblasts and Colon Cancer Cells. | ||||||||||
| Author: | Kaler, Pawan|Owusu, Benjamin Y|Augenlicht, Leonard|Klampfer, Lidija | ||||||||||
| PMID: | 24818101 | ||||||||||
| 50. | |||||||||||
| Journal: | J Clin Invest. 2014 Jun;124(6):2472-82. | ||||||||||
| Title: | Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis. | ||||||||||
| Author: | Choi, Sung Hee|Kim, Byung-Gyu|Robinson, Janet|Fink, Steve|Yan, Min|Sporn, Michael B|Markowitz, Sanford D|Letterio, John J | ||||||||||
| PMID: | 24837432 | ||||||||||
| 51. | |||||||||||
| Journal: | PLoS One. 2014 Oct 1;9(10):e109048. | ||||||||||
| Title: | Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach. | ||||||||||
| Author: | Serra, Diana|Rufino, Ana T|Mendes, Alexandrina F|Almeida, Leonor M|Dinis, Teresa C P | ||||||||||
| PMID: | 25271420 | ||||||||||
| 52. | |||||||||||
| Journal: | Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1548-55. | ||||||||||
| Title: | Expressional STAT3/STAT5 Ratio is an Independent Prognostic Marker in Colon Carcinoma. | ||||||||||
| Author: | Klupp, Fee|Diers, Johannes|Kahlert, Christoph|Neumann, Lena|Halama, Niels|Franz, Clemens|Schmidt, Thomas|Lasitschka, Felix|Warth, Arne|Weitz, Juergen|Koch, Moritz|Schneider, Martin|Ulrich, Alexis | ||||||||||
| PMID: | 25773877 | ||||||||||
| 53. | |||||||||||
| Journal: | DNA Cell Biol. 2015 Aug;34(8):541-9. | ||||||||||
| Title: | The Tumor Suppressive Effects of HPP1 Are Mediated Through JAK-STAT-Interferon Signaling Pathways. | ||||||||||
| Author: | Hernandez, Jonathan M|Elahi, Abul|Clark, Whalen|Humphries, Leigh Ann|Wang, Jian|Achille, Alex|Seto, Ed|Shibata, David | ||||||||||
| PMID: | 26061044 | ||||||||||
| 54. | |||||||||||
| Journal: | Cell Biosci. 2015 Sep 17;5:53. | ||||||||||
| Title: | Integrated transcriptional profiling and genomic analyses reveal RPN2 and HMGB1 as promising biomarkers in colorectal cancer. | ||||||||||
| Author: | Zhang, Jialing|Yan, Bin|Spath, Stephan Stanislaw|Qun, Hu|Cornelius, Shaleeka|Guan, Daogang|Shao, Jiaofang|Hagiwara, Koichi|Van Waes, Carter|Chen, Zhong|Su, Xiulan|Bi, Yongyi | ||||||||||
| PMID: | 26388988 | ||||||||||
| 55. | |||||||||||
| Journal: | Sci Rep. 2015 Sep 22;5:14301. | ||||||||||
| Title: | Tumour-promoting role of SOCS1 in colorectal cancer cells. | ||||||||||
| Author: | Tobelaim, William S|Beaurivage, Claudia|Champagne, Audrey|Pomerleau, Veronique|Simoneau, Aline|Chababi, Walid|Yeganeh, Mehdi|Thibault, Philippe|Klinck, Roscoe|Carrier, Julie C|Ferbeyre, Gerardo|Ilangumaran, Subburaj|Saucier, Caroline | ||||||||||
| PMID: | 26391193 | ||||||||||
| 56. | |||||||||||
| Journal: | Mol Cancer Ther. 2016 Dec;15(12):3055-3063. | ||||||||||
| Title: | STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A. | ||||||||||
| Author: | Wang, Shuo|Darini, Cedric|Desaubry, Laurent|Koromilas, Antonis E | ||||||||||
| PMID: | 27913706 | ||||||||||
| 57. | |||||||||||
| Journal: | Oncoimmunology. 2016 Aug 3;5(9):e1211219. | ||||||||||
| Title: | Tim-3 promotes tumor-promoting M2 macrophage polarization by binding to STAT1 and suppressing the STAT1-miR-155 signaling axis. | ||||||||||
| Author: | Jiang, Xingwei|Zhou, Tingting|Xiao, Yan|Yu, Jiahui|Dou, Shuaijie|Chen, Guojiang|Wang, Renxi|Xiao, He|Hou, Chunmei|Wang, Wei|Shi, Qingzhu|Feng, Jiannan|Ma, Yuanfang|Shen, Beifen|Li, Yan|Han, Gencheng | ||||||||||
| PMID: | 27757304 | ||||||||||
| 58. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 8;7(45):73003-73015. | ||||||||||
| Title: | Elevated level of interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3. | ||||||||||
| Author: | Ma, Yanhui|Chen, Lei|Xie, Guohua|Zhou, Yunlan|Yue, Chaoyan|Yuan, Xiangliang|Zheng, Yingxia|Wang, Weiwei|Deng, Lin|Shen, Lisong | ||||||||||
| PMID: | 27682874 | ||||||||||
| 59. | |||||||||||
| Journal: | J Med Chem. 2016 Oct 27;59(20):9337-9349. | ||||||||||
| Title: | Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening. | ||||||||||
| Author: | Czodrowski, Paul|Mallinger, Aurelie|Wienke, Dirk|Esdar, Christina|Poschke, Oliver|Busch, Michael|Rohdich, Felix|Eccles, Suzanne A|Ortiz-Ruiz, Maria-Jesus|Schneider, Richard|Raynaud, Florence I|Clarke, Paul A|Musil, Djordje|Schwarz, Daniel|Dale, Trevor|Urb | ||||||||||
| PMID: | 27490956 | ||||||||||
| 60. | |||||||||||
| Journal: | ACS Med Chem Lett. 2016 Mar 28;7(6):573-8. | ||||||||||
| Title: | 2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19. | ||||||||||
| Author: | Mallinger, Aurelie|Schiemann, Kai|Rink, Christian|Sejberg, Jimmy|Honey, Mark A|Czodrowski, Paul|Stubbs, Mark|Poeschke, Oliver|Busch, Michael|Schneider, Richard|Schwarz, Daniel|Musil, Djordje|Burke, Rosemary|Urbahns, Klaus|Workman, Paul|Wienke, Dirk|Clarke | ||||||||||
| PMID: | 27326329 | ||||||||||
| 61. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 9;7(32):51096-51106. | ||||||||||
| Title: | The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth. | ||||||||||
| Author: | Nivarthi, Harini|Gordziel, Claire|Themanns, Madeleine|Kramer, Nina|Eberl, Markus|Rabe, Bjorn|Schlederer, Michaela|Rose-John, Stefan|Knosel, Thomas|Kenner, Lukas|Freund, Patricia|Aberger, Fritz|Han, Xiaonan|Kralovics, Robert|Dolznig, Helmut|Jennek, Susanne | ||||||||||
| PMID: | 27191495 | ||||||||||
| 62. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 15;7(11):12917-26. | ||||||||||
| Title: | A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells. | ||||||||||
| Author: | Zhao, Chongqiang|Wang, Wenlong|Yu, Wenying|Jou, David|Wang, Yina|Ma, Haiyan|Xiao, Hui|Qin, Hua|Zhang, Cuntai|Lu, Jiagao|Li, Sheng|Li, Chenglong|Lin, Jiayuh|Lin, Li | ||||||||||
| PMID: | 26883202 | ||||||||||
| 63. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2016 Mar 1;26(5):1443-51. | ||||||||||
| Title: | Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophore. | ||||||||||
| Author: | Schiemann, Kai|Mallinger, Aurelie|Wienke, Dirk|Esdar, Christina|Poeschke, Oliver|Busch, Michael|Rohdich, Felix|Eccles, Suzanne A|Schneider, Richard|Raynaud, Florence I|Czodrowski, Paul|Musil, Djordje|Schwarz, Daniel|Urbahns, Klaus|Blagg, Julian | ||||||||||
| PMID: | 26852363 | ||||||||||
| 64. | |||||||||||
| Journal: | Sci Rep. 2016 Jan 13;6:19229. | ||||||||||
| Title: | FAS rs2234767 and rs1800682 polymorphisms jointly contributed to risk of colorectal cancer by affecting SP1/STAT1 complex recruitment to chromatin. | ||||||||||
| Author: | Wang, Shizhi|Wu, Shenshen|Meng, Qingtao|Li, Xiaobo|Zhang, Jinchun|Chen, Rui|Wang, Meilin | ||||||||||
| PMID: | 26759270 | ||||||||||
| 65. | |||||||||||
| Journal: | J Natl Cancer Inst. 2015 Dec 30;108(6):djv394. | ||||||||||
| Title: | Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer. | ||||||||||
| Author: | Santoro, Valeria|Jia, Ruochen|Thompson, Hannah|Nijhuis, Anke|Jeffery, Rosemary|Kiakos, Konstantinos|Silver, Andrew R|Hartley, John A|Hochhauser, Daniel | ||||||||||
| PMID: | 26719345 | ||||||||||
| 66. | |||||||||||
| Journal: | Oncol Rep. 2016 Mar;35(3):1273-80. | ||||||||||
| Title: | FAM172A modulates apoptosis and proliferation of colon cancer cells via STAT1 binding to its promoter. | ||||||||||
| Author: | Qian, Kai|Zhang, Jinqian|Lu, Jingbo|Liu, Wenjun|Yao, Xingxing|Chen, Qing|Lu, Shun|Xiang, Guoan|Liu, Hao | ||||||||||
| PMID: | 26676844 | ||||||||||
| 67. | |||||||||||
| Journal: | ACS Med Chem Lett. 2016 Jan 6;7(3):223-8. | ||||||||||
| Title: | Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells. | ||||||||||
| Author: | Koehler, Michael F T|Bergeron, Philippe|Blackwood, Elizabeth M|Bowman, Krista|Clark, Kevin R|Firestein, Ron|Kiefer, James R|Maskos, Klaus|McCleland, Mark L|Orren, Linda|Salphati, Laurent|Schmidt, Steve|Schneider, Elisabeth V|Wu, Jiansheng|Beresini, Mauree | ||||||||||
| PMID: | 26985305 | ||||||||||
| 68. | |||||||||||
| Journal: | Oncoimmunology. 2017 Feb 6;6(4):e1288330. | ||||||||||
| Title: | Digital analysis and epigenetic regulation of the signature of rejection in colorectal cancer. | ||||||||||
| Author: | Koelzer, Viktor H|Sokol, Lena|Zahnd, Stefan|Christe, Lucine|Dawson, Heather|Berger, Martin D|Inderbitzin, Daniel|Zlobec, Inti|Lugli, Alessandro | ||||||||||
| PMID: | 28507795 | ||||||||||
| 69. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 22;8(33):54838-54857. | ||||||||||
| Title: | Synergistic inhibition of colon cancer growth by the combination of methylglyoxal and silencing of glyoxalase I mediated by the STAT1 pathway. | ||||||||||
| Author: | Chen, Yuan|Fang, Lei|Li, Gefei|Zhang, Jiali|Li, Changxi|Ma, Mengni|Guan, Chen|Bai, Fumao|Lyu, Jianxin|Meng, Qing H | ||||||||||
| PMID: | 28903386 | ||||||||||
| 70. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2017 Sep 9;491(1):159-165. | ||||||||||
| Title: | Inhibition of IL-6/STAT3 signaling in human cancer cells using Evista. | ||||||||||
| Author: | Shi, Wei|Yan, Dan|Zhao, Chongqiang|Xiao, Miaomiao|Wang, Yina|Ma, Haiyan|Liu, Tianshu|Qin, Hua|Zhang, Cuntai|Li, Chenglong|Lin, Jiayuh|Li, Sheng|Lv, Jiagao|Lin, Li | ||||||||||
| PMID: | 28711499 | ||||||||||
| 71. | |||||||||||
| Journal: | Mediators Inflamm. 2017;2017:5958429. | ||||||||||
| Title: | Proinflammatory Cytokines IL-6 and TNF-alpha Increased Telomerase Activity through NF-kappaB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells. | ||||||||||
| Author: | Chung, Seyung S|Wu, Yong|Okobi, Quincy|Adekoya, Debbie|Atefi, Mohammad|Clarke, Orette|Dutta, Pranabananda|Vadgama, Jaydutt V | ||||||||||
| PMID: | 28676732 | ||||||||||
| 72. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 25;8(17):29101-29115. | ||||||||||
| Title: | The miR-124-p63 feedback loop modulates colorectal cancer growth. | ||||||||||
| Author: | Liu, Kuijie|Yao, Hongliang|Lei, Sanlin|Xiong, Li|Qi, Haizhi|Qian, Ke|Liu, Jiqiang|Wang, Peng|Zhao, Hua | ||||||||||
| PMID: | 28418858 | ||||||||||
| 73. | |||||||||||
| Journal: | Int J Mol Sci. 2017 Mar 9;18(3). pii: ijms18030570. | ||||||||||
| Title: | Blockage of Glyoxalase I Inhibits Colorectal Tumorigenesis and Tumor Growth via Upregulation of STAT1, p53, and Bax and Downregulation of c-Myc and Bcl-2. | ||||||||||
| Author: | Chen, Yuan|Fang, Lei|Zhang, Jiali|Li, Gefei|Ma, Mengni|Li, Changxi|Lyu, Jianxin|Meng, Qing H | ||||||||||
| PMID: | 28282916 | ||||||||||
| 74. | |||||||||||
| Journal: | Anticancer Res. 2017 Feb;37(2):445-453. | ||||||||||
| Title: | Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells. | ||||||||||
| Author: | Chung, Seyung S|Adekoya, Debbie|Enenmoh, Ikechukwu|Clarke, Orette|Wang, Piwen|Sarkyssian, Marianna|Wu, Yong|Vadgama, Jaydutt V | ||||||||||
| PMID: | 28179289 | ||||||||||
| 75. | |||||||||||
| Journal: | Biosci Trends. 2017 Mar 22;11(1):1-8. | ||||||||||
| Title: | Steering of carcinoma progression by the YIN/YANG interaction of STAT1/STAT3. | ||||||||||
| Author: | Friedrich, Karlheinz|Dolznig, Helmut|Han, Xiaonan|Moriggl, Richard | ||||||||||
| PMID: | 28154246 | ||||||||||
| 76. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 31;8(5):7586-7597. | ||||||||||
| Title: | T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. | ||||||||||
| Author: | Liu, Wen|Guo, Wenjie|Shen, Lihong|Chen, Zhen|Luo, Qiong|Luo, Xiaolin|Feng, GenSheng|Shu, Yongqian|Gu, Yanhong|Xu, Qiang|Sun, Yang | ||||||||||
| PMID: | 27935860 | ||||||||||
| 77. | |||||||||||
| Journal: | Oncogene. 2017 May 11;36(19):2655-2666. | ||||||||||
| Title: | The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network. | ||||||||||
| Author: | Jia, H|Song, L|Cong, Q|Wang, J|Xu, H|Chu, Y|Li, Q|Zhang, Y|Zou, X|Zhang, C|Chin, Y E|Zhang, X|Li, Z|Zhu, K|Wang, B|Peng, H|Hou, Z | ||||||||||
| PMID: | 27893714 | ||||||||||
| 78. | |||||||||||
| Journal: | Cell Mol Immunol. 2018 Feb;15(2):135-145. | ||||||||||
| Title: | HSP70L1-mediated intracellular priming of dendritic cell vaccination induces more potent CTL response against cancer. | ||||||||||
| Author: | Liu, Shuxun|Yi, Lin|Ling, Ma|Jiang, Jinxia|Song, Lijun|Liu, Juan|Cao, Xuetao | ||||||||||
| PMID: | 27345726 | ||||||||||
| 79. | |||||||||||
| Journal: | Gastroenterology. 2018 Feb;154(3):637-651.e7. | ||||||||||
| Title: | MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors. | ||||||||||
| Author: | Liu, Ronghua|Lu, Zhou|Gu, Jie|Liu, Jiajing|Huang, Enyu|Liu, Xiaoming|Wang, Luman|Yang, Jiao|Deng, Yuting|Qian, Jiawen|Luo, Feifei|Wang, Zhiming|Zhang, Hushan|Jiang, Xuechao|Zhang, Dan|Qian, Jing|Liu, Guangwei|Zhu, Hongguang|Qian, Youcun|Liu, Zhanju|Chu, Y | ||||||||||
| PMID: | 29031499 | ||||||||||
| 80. | |||||||||||
| Journal: | Clin Cancer Res. 2018 Jan 1;24(1):224-233. | ||||||||||
| Title: | KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer. | ||||||||||
| Author: | Lal, Neeraj|White, Brian S|Goussous, Ghaleb|Pickles, Oliver|Mason, Mike J|Beggs, Andrew D|Taniere, Philippe|Willcox, Benjamin E|Guinney, Justin|Middleton, Gary W | ||||||||||
| PMID: | 29061646 | ||||||||||
| 81. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2018 Feb;144(2):295-308. | ||||||||||
| Title: | The function of BTG3 in colorectal cancer cells and its possible signaling pathway. | ||||||||||
| Author: | Lv, Chi|Wang, Heling|Tong, Yuxin|Yin, Hongzhuan|Wang, Dalu|Yan, Zhaopeng|Liang, Yichao|Wu, Di|Su, Qi | ||||||||||
| PMID: | 29270670 | ||||||||||
| 82. | |||||||||||
| Journal: | Mol Oncol. 2018 Apr;12(4):514-528. | ||||||||||
| Title: | STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer. | ||||||||||
| Author: | Crncec, Ilija|Modak, Madhura|Gordziel, Claire|Svinka, Jasmin|Scharf, Irene|Moritsch, Stefan|Pathria, Paulina|Schlederer, Michaela|Kenner, Lukas|Timelthaler, Gerald|Muller, Mathias|Strobl, Birgit|Casanova, Emilio|Bayer, Editha|Mohr, Thomas|Stockl, Johannes | ||||||||||
| PMID: | 29419930 | ||||||||||