Primary Site >> Colorectal Cancer

Gene >> SSSCA1

Journal: Mol Carcinog. 1999 Nov;26(3):172-9.
Title: Reduced expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in human colon cancer.
Author: Sgambato, A|Ratto, C|Faraglia, B|Merico, M|Ardito, R|Schinzari, G|Romano, G|Cittadini, A R
PMID: 10559792
Journal: Mod Pathol. 1999 Aug;12(8):751-5.
Title: Levels of expression of p27KIP1 protein in human prostate and prostate cancer: an immunohistochemical analysis.
Author: Erdamar, S|Yang, G|Harper, J W|Lu, X|Kattan, M W|Thompson, T C|Wheeler, T M
PMID: 10463475
Journal: J Clin Lab Anal. 1999;13(6):291-5.
Title: p27 cell-cycle inhibitor is inversely correlated with lymph node metastases in right-sided colon cancer.
Author: Liu, D F|Ferguson, K|Cooper, G S|Grady, W M|Willis, J
PMID: 10633297
Journal: J Surg Res. 2000 Jul;92(1):78-84.
Title: p27(kip1) expression in rectal cancer correlates with disease-free survival.
Author: Gunther, K|Jung, A|Volker, U|Meyer, M|Brabletz, T|Matzel, K E|Reymond, M A|Kirchner, T|Hohenberger, W
PMID: 10864486
Journal: Urology. 2000 Oct 1;56(4):689-95.
Title: Cyclin-dependent kinase inhibitor P27(KIP1) is expressed preferentially in early stages of urothelial carcinoma.
Author: Franke, K H|Miklosi, M|Goebell, P|Clasen, S|Steinhoff, C|Anastasiadis, A G|Gerharz, C|Schulz, W A
PMID: 11018640
Journal: Biomarkers. 2000;5(3):225-34.
Title: Expression of p27(Kip1) and bcl-2, cigarette smoking, and colorectal cancer risk.
Author: Ishibe, N|Freedman, A N|Michalek, A M|Iacobuziodonahue, C|Mettlin, C J|Petrelli, N J|Asirwatham, J E|Hamilton, S R
PMID: 23889224
Journal: Biochem Biophys Res Commun. 2001 Apr 27;283(1):80-5.
Title: 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression.
Author: Gaschott, T|Wachtershauser, A|Steinhilber, D|Stein, J
PMID: 11322770
Journal: Biochem Biophys Res Commun. 2002 Jan 11;290(1):504-9.
Title: ZK 156718, a low calcemic, antiproliferative, and prodifferentiating vitamin D analog.
Author: Gaschott, Tanja|Steinmeyer, Andreas|Steinhilber, Dieter|Stein, Jurgen
PMID: 11779200
Journal: Cancer Cell. 2002 May;1(4):355-68.
Title: Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice.
Author: Philipp-Staheli, Jeannette|Kim, Kyung-Hoon|Payne, Shannon R|Gurley, Kay E|Liggitt, Denny|Longton, Gary|Kemp, Christopher J
PMID: 12086850
Journal: J Clin Endocrinol Metab. 2002 Oct;87(10):4728-35.
Title: Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth.
Author: Martelli, Maria Luisa|Iuliano, Rodolfo|Le Pera, Ilaria|Sama', Irene|Monaco, Carmen|Cammarota, Simona|Kroll, Todd|Chiariotti, Lorenzo|Santoro, Massimo|Fusco, Alfredo
PMID: 12364466
Journal: Eur J Cancer. 2002 Dec;38(18):2446-54.
Title: Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest.
Author: Murillo, G|Salti, G I|Kosmeder, J W 2nd|Pezzuto, J M|Mehta, R G
PMID: 12460790
Journal: Oncol Rep. 2003 Jul-Aug;10(4):827-31.
Title: Prognostic significance of p27/kip1 and apoptosis in patients with colorectal carcinoma.
Author: Noguchi, Tsuyoshi|Kikuchi, Ryuichi|Ono, Kiyoshi|Takeno, Shinsuke|Moriyama, Hatsuo|Uchida, Yuzo
PMID: 12792730
Journal: J Surg Res. 2003 Aug;113(2):179-88.
Title: P27 does not predict histopathological response to radiochemotherapy in rectal cancer.
Author: Gunther, Klaus|Dimmler, Arno|Rodel, Franz|Reulbach, Udo|Merkel, Susanne|Bittorf, Birgit R|Matzel, Klaus E|Papadopoulos, Thomas|Hohenberger, Werner|Sauer, Rolf|Rodel, Claus
PMID: 12957127
Journal: J Cancer Res Clin Oncol. 2003 Aug;129(8):449-55.
Title: Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum.
Author: Mitomi, Hiroyuki|Sada, Miwa|Kobayashi, Kiyonori|Igarashi, Masahiro|Mori, Akio|Kanazawa, Hideki|Nishiyama, Yasuhiko|Ihara, Atsushi|Otani, Yoshimasa
PMID: 12884030
Journal: Clin Cancer Res. 2003 Jul;9(7):2457-64.
Title: A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.
Author: Daneshmand, Manijeh|Parolin, Doris A E|Hirte, Holger W|Major, Pierre|Goss, Glenwood|Stewart, David|Batist, Gerald|Miller, Wilson H Jr|Matthews, Sarah|Seymour, Lesley|Lorimer, Ian A J
PMID: 12855618
Journal: Am J Pharmacogenomics. 2003;3(2):73-88.
Title: Implications of genetic testing in the management of colorectal cancer.
Author: Stoehlmacher, Jan|Lenz, Heinz-Josef
PMID: 12749725
Journal: J Gene Med. 2003 Apr;5(4):287-99.
Title: 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells.
Author: Uchida, Hiroaki|Shinoura, Nobusada|Kitayama, Joji|Watanabe, Toshiaki|Nagawa, Hirokazu|Hamada, Hirofumi
PMID: 12692863
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: Cancer Invest. 2004;22(5):762-73.
Title: Tailored chemotherapy for colorectal cancer: a new approach to therapy.
Author: Iqbal, Syma|Stoehlmacher, Jan|Lenz, Heinz-Josef
PMID: 15581057
Journal: Eur J Med Chem. 2005 Jan;40(1):85-92.
Title: Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines.
Author: Mahboobi, Siavosh|Sellmer, Andreas|Eichhorn, Emerich|Beckers, Thomas|Fiebig, Heinz-Herbert|Kelter, Gerhard
PMID: 15642413
Journal: Anticancer Drugs. 2006 Jun;17(5):521-6.
Title: N-methylformamide and 9-hydroxystearic acid: two anti-proliferative and differentiating agents with different modes of action in colon cancer cells.
Author: Pagnotta, Eleonora|Calonghi, Natalia|Boga, Carla|Masotti, Lanfranco
PMID: 16702808
Journal: Cancer. 2006 Aug 15;107(4):668-75.
Title: Prognostic role of p27Kip1 deregulation in colorectal cancer.
Author: Hershko, Dan D|Shapira, Ma'anit
PMID: 16826582
Journal: J Med Chem. 2006 Sep 21;49(19):5769-76.
Title: [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
Author: Mahboobi, Siavosh|Sellmer, Andreas|Hocher, Heymo|Eichhorn, Emerich|Bar, Thomas|Schmidt, Mathias|Maier, Thomas|Stadlwieser, Josef F|Beckers, Thomas L
PMID: 16970401
Journal: World J Gastroenterol. 2006 Oct 21;12(39):6299-304.
Title: Cytoplasmic expression of p27(kip1) is associated with a favourable prognosis in colorectal cancer patients.
Author: Watson, Nicholas F S|Durrant, Lindy G|Scholefield, John H|Madjd, Zahra|Scrimgeour, Duncan|Spendlove, Ian|Ellis, Ian O|Patel, Poulam M
PMID: 17072952
Journal: Oncology. 2007;73(1-2):52-7.
Title: Colorectal cancer or colon and rectal cancer? Clinicopathological comparison between colonic and rectal carcinomas.
Author: Li, M|Li, J Y|Zhao, A L|Gu, J
PMID: 18334831
Journal: Int J Oncol. 2007 Sep;31(3):633-41.
Title: The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.
Author: Fedier, Andre|Dedes, Konstantin J|Imesch, Patrick|Von Bueren, Andre O|Fink, Daniel
PMID: 17671692
Journal: Dis Colon Rectum. 2007 Nov;50(11):1887-98.
Title: Survival stratification panel of colorectal carcinoma with combined expression of carcinoembryonic antigen, matrix metalloproteinases-2, and p27 kip1.
Author: Li, Ming|Li, Ji-You|Zhao, Ai-Lian|He, Jing-Sheng|Zhou, Li-Xin|Li, Ying-Ai|Gu, Jin
PMID: 17882488
Journal: Int J Cancer. 2008 May 1;122(9):2115-24.
Title: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
Author: Xiao, Hang|Zhang, Qiang|Lin, Yong|Reddy, Bandaru S|Yang, Chung S
PMID: 18172863
Journal: Ann Surg Oncol. 2008 May;15(5):1429-39.
Title: Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features.
Author: Leopoldo, Sarli|Lorena, Bottarelli|Cinzia, Azzoni|Gabriella, Di Cola|Angela Luciana, Barilli|Renato, Costi|Antonio, Mazzeo|Carlo, Salvemini|Cristina, Porrini|Stefano, Cecchini|Maurizio, Taglia|Luigi, Roncoroni|Cesare, Bordi
PMID: 18301950
Journal: Am J Pathol. 2008 Jul;173(1):217-28.
Title: Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis.
Author: Fujita, Takeo|Liu, Weijun|Doihara, Hiroyoshi|Wan, Yong
PMID: 18535175
Journal: World J Gastroenterol. 2008 Oct 14;14(38):5827-33.
Title: Antitumor bioactivity of adenovirus-mediated p27mt in colorectal cancer cell line SW480.
Author: Sun, Ze-Qun|Deng, Chang-Sheng|Xu, Shao-Yong|Du, Yong
PMID: 18855981
Journal: Clin Cancer Res. 2009 Mar 15;15(6):2116-22.
Title: p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803.
Author: Bertagnolli, Monica M|Warren, Robert S|Niedzwiecki, Donna|Mueller, Elke|Compton, Carolyn C|Redston, Mark|Hall, Margaret|Hahn, Hejin P|Jewell, Scott D|Mayer, Robert J|Goldberg, Richard M|Saltz, Leonard B|Loda, Massimo
PMID: 19276255
Journal: Cancer Res. 2010 Feb 15;70(4):1469-78.
Title: NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer.
Author: Sikandar, Shaheen S|Pate, Kira T|Anderson, Scott|Dizon, Diana|Edwards, Robert A|Waterman, Marian L|Lipkin, Steven M
PMID: 20145124
Journal: Int J Colorectal Dis. 2010 Jul;25(7):795-804.
Title: Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib.
Author: Voutsadakis, Ioannis A|Patrikidou, Anna|Tsapakidis, Konstantinos|Karagiannaki, Aristea|Hatzidaki, Eleana|Stathakis, Nikolaos E|Papandreou, Christos N
PMID: 20397022
Journal: Mol Cancer Res. 2010 May;8(5):798-805.
Title: STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells.
Author: Wang, Shuo|Raven, Jennifer F|Koromilas, Antonis E
PMID: 20407011
Journal: Anticancer Drugs. 2010 Oct;21(9):850-60.
Title: Isoprenoid geranylgeranylacetone inhibits human colon cancer cells through induction of apoptosis and cell cycle arrest.
Author: Yoshikawa, Naoyuki|Tsuno, Nelson H|Okaji, Yurai|Kawai, Kazushige|Shuno, Yasutaka|Nagawa, Hirokazu|Oshima, Noriko|Takahashi, Koki
PMID: 20724917
Journal: J Surg Res. 2011 May 15;167(2):231-6.
Title: Do young patients with colorectal cancer have a poorer prognosis than old patients?
Author: Li, Ming|Li, Ji-You|Zhao, Ai-Lian|Gu, Jin
PMID: 21316708
Journal: PLoS One. 2011;6(7):e21651.
Title: EZH2 depletion blocks the proliferation of colon cancer cells.
Author: Fussbroich, Bettina|Wagener, Nina|Macher-Goeppinger, Stephan|Benner, Axel|Falth, Maria|Sultmann, Holger|Holzer, Angela|Hoppe-Seyler, Karin|Hoppe-Seyler, Felix
PMID: 21765901
Journal: Oncogene. 2012 Sep 13;31(37):4128-38.
Title: Involvement of the SKP2-p27(KIP1) pathway in suppression of cancer cell proliferation by RECK.
Author: Yoshida, Y|Ninomiya, K|Hamada, H|Noda, M
PMID: 22158033
Journal: Hum Pathol. 2013 Apr;44(4):591-7.
Title: Expression of p27, COX-2, MLH1, and MSH2 in young patients with colon carcinoma and correlation with morphologic findings.
Author: Kenney, Barton|Deng, Yanhong|Mitchell, Kisha
PMID: 23084580
Journal: Cancer Gene Ther. 2013 Dec;20(12):690-4.
Title: S-phase kinase-associated protein 2 knockdown blocks colorectal cancer growth via regulation of both p27 and p16 expression.
Author: Xu, S-Y|Wang, F|Wei, G|Wang, B|Yang, J-Y|Huang, Y-Z|Zhang, L|Zheng, F|Guo, L-Y|Wang, J-N|Tang, J-M
PMID: 24336114
Journal: Cancer Epidemiol Biomarkers Prev. 2013 Jun;22(6):1142-52.
Title: Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer.
Author: Yamauchi, Mai|Lochhead, Paul|Imamura, Yu|Kuchiba, Aya|Liao, Xiaoyun|Qian, Zhi Rong|Nishihara, Reiko|Morikawa, Teppei|Shima, Kaori|Wu, Kana|Giovannucci, Edward|Meyerhardt, Jeffrey A|Fuchs, Charles S|Chan, Andrew T|Ogino, Shuji
PMID: 23629521
Journal: Free Radic Biol Med. 2013 Apr;57:162-75.
Title: Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts.
Author: Doroshow, James H|Gaur, Shikha|Markel, Susan|Lu, Jiamo|van Balgooy, Josephus|Synold, Timothy W|Xi, Bixin|Wu, Xiwei|Juhasz, Agnes
PMID: 23314043
Journal: Int J Cancer. 2014 Dec 1;135(11):2528-36.
Title: Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer.
Author: Ishikawa, S|Hayashi, H|Kinoshita, K|Abe, M|Kuroki, H|Tokunaga, R|Tomiyasu, S|Tanaka, H|Sugita, H|Arita, T|Yagi, Y|Watanabe, M|Hirota, M|Baba, H
PMID: 24346863
Journal: Mol Med Rep. 2014 Aug;10(2):1129-35.
Title: Interference of Skp2 effectively inhibits the development and metastasis of colon carcinoma.
Author: Chen, Haijin|Mo, Xiaodong|Yu, Jinlong|Huang, Shuxin|Huang, Zonghai|Gao, Liping
PMID: 24913024
Journal: RNA Biol. 2015;12(3):276-89.
Title: microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs.
Author: Pan, Yi|Liang, Hongwei|Chen, Weixu|Zhang, Hongjie|Wang, Nan|Wang, Feng|Zhang, Suyang|Liu, Yanqing|Zhao, Chihao|Yan, Xin|Zhang, Junfeng|Zhang, Chen-Yu|Gu, Hongwei|Zen, Ke|Chen, Xi
PMID: 25826661
Journal: Mol Carcinog. 2016 May;55(5):671-87.
Title: Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis.
Author: Bian, Benjamin|Mongrain, Sebastien|Cagnol, Sebastien|Langlois, Marie-Josee|Boulanger, Jim|Bernatchez, Gerald|Carrier, Julie C|Boudreau, Francois|Rivard, Nathalie
PMID: 25808857
Journal: Int J Oncol. 2016 Mar;48(3):1305.
Title: [Corrigendum] Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells.
Author: Izutani, Yasuyuki|Yogosawa, Shingo|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 26718100
Journal: Clin Cancer Res. 2016 Oct 1;22(19):4766-4775.
Title: Physical Activity and Cancer Outcomes: A Precision Medicine Approach.
Author: Friedenreich, Christine M|Neilson, Heather K|Farris, Megan S|Courneya, Kerry S
PMID: 27407093
Journal: J BUON. 2017 Sep-Oct;22(5):1122-1130.
Title: The prognostic role of Skp2 and the tumor suppressor protein p27 in colorectal cancer.
Author: Vasile Bochis, Ovidiu|Achimas-Cadariu, Patriciu|Vlad, Catalin|Fetica, Bogdan|Corneliu Leucuta, Daniel|Ioan Busuioc, Constantin|Irimie, Alexandru
PMID: 29135092
Journal: Exp Mol Med. 2017 Nov 24;49(11):e399.
Title: Therapeutic inhibition of SGK1 suppresses colorectal cancer.
Author: Liang, Xuchun|Lan, Chunling|Jiao, Guanming|Fu, Wencheng|Long, Xuesha|An, Yu|Wang, Kejin|Zhou, Jinzhe|Chen, Ting|Li, Yongqin|Xu, Jiahong|Huang, Qi|Xu, Bin|Xiao, Junjie
PMID: 29170478
Journal: Cell Physiol Biochem. 2018;46(5):2138-2148.
Title: Tumor Suppressive Role of ARHGAP17 in Colon Cancer Through Wnt/beta-Catenin Signaling.
Author: Pan, Shengli|Deng, Yingying|Fu, Jun|Zhang, Yuhao|Zhang, Zhijin|Ru, Xiaokun|Qin, Xianju
PMID: 29730655
Journal: Oncol Lett. 2018 Oct;16(4):5275-5281.
Title: Increased EZH2 expression during the adenoma-carcinoma sequence in colorectal cancer.
Author: Ohuchi, Mayuko|Sakamoto, Yasuo|Tokunaga, Ryuma|Kiyozumi, Yuki|Nakamura, Kenichi|Izumi, Daisuke|Kosumi, Keisuke|Harada, Kazuto|Kurashige, Junji|Iwatsuki, Masaaki|Baba, Yoshifumi|Miyamoto, Yuji|Yoshida, Naoya|Shono, Takashi|Naoe, Hideaki|Sasaki, Yutaka|Baba
PMID: 30214616