Primary Site >> Colorectal Cancer
Gene >> SSSCA1
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Ref: Levels of expression of p27KIP1 protein in human prostate and prostate cancer: an immunohistochemical analysis. PMID: 10463475 Ref: Reduced expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in human colon cancer. PMID: 10559792 Ref: p27 cell-cycle inhibitor is inversely correlated with lymph node metastases in right-sided colon cancer. PMID: 10633297 |
Ref: p27(kip1) expression in rectal cancer correlates with disease-free survival. PMID: 10864486 Ref: Cyclin-dependent kinase inhibitor P27(KIP1) is expressed preferentially in early stages of urothelial carcinoma. PMID: 11018640 Ref: Expression of p27(Kip1) and bcl-2, cigarette smoking, and colorectal cancer risk. PMID: 23889224 |
Ref: 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression. PMID: 11322770 |
Ref: ZK 156718, a low calcemic, antiproliferative, and prodifferentiating vitamin D analog. PMID: 11779200 Ref: Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice. PMID: 12086850 Ref: Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth. PMID: 12364466 Ref: Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. PMID: 12460790 |
Ref: 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells. PMID: 12692863 Ref: Implications of genetic testing in the management of colorectal cancer. PMID: 12749725 Ref: Prognostic significance of p27/kip1 and apoptosis in patients with colorectal carcinoma. PMID: 12792730 Ref: A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. PMID: 12855618 Ref: Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum. PMID: 12884030 Ref: P27 does not predict histopathological response to radiochemotherapy in rectal cancer. PMID: 12957127 |
Ref: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. PMID: 15526363 Ref: Tailored chemotherapy for colorectal cancer: a new approach to therapy. PMID: 15581057 |
Ref: Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines. PMID: 15642413 |
Ref: N-methylformamide and 9-hydroxystearic acid: two anti-proliferative and differentiating agents with different modes of action in colon cancer cells. PMID: 16702808 Ref: Prognostic role of p27Kip1 deregulation in colorectal cancer. PMID: 16826582 Ref: [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines. PMID: 16970401 Ref: Cytoplasmic expression of p27(kip1) is associated with a favourable prognosis in colorectal cancer patients. PMID: 17072952 |
Ref: The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells. PMID: 17671692 Ref: Survival stratification panel of colorectal carcinoma with combined expression of carcinoembryonic antigen, matrix metalloproteinases-2, and p27 kip1. PMID: 17882488 Ref: Colorectal cancer or colon and rectal cancer? Clinicopathological comparison between colonic and rectal carcinomas. PMID: 18334831 |
Ref: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells. PMID: 18172863 Ref: Two subtypes of mucinous adenocarcinoma of the colorectum: clinicopathological and genetic features. PMID: 18301950 Ref: Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis. PMID: 18535175 Ref: Antitumor bioactivity of adenovirus-mediated p27mt in colorectal cancer cell line SW480. PMID: 18855981 |
Ref: p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803. PMID: 19276255 |
Ref: NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. PMID: 20145124 Ref: Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. PMID: 20397022 Ref: STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells. PMID: 20407011 Ref: Isoprenoid geranylgeranylacetone inhibits human colon cancer cells through induction of apoptosis and cell cycle arrest. PMID: 20724917 |
Ref: Do young patients with colorectal cancer have a poorer prognosis than old patients? PMID: 21316708 Ref: EZH2 depletion blocks the proliferation of colon cancer cells. PMID: 21765901 |
Ref: Involvement of the SKP2-p27(KIP1) pathway in suppression of cancer cell proliferation by RECK. PMID: 22158033 |
Ref: Expression of p27, COX-2, MLH1, and MSH2 in young patients with colon carcinoma and correlation with morphologic findings. PMID: 23084580 Ref: Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts. PMID: 23314043 Ref: Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer. PMID: 23629521 Ref: S-phase kinase-associated protein 2 knockdown blocks colorectal cancer growth via regulation of both p27 and p16 expression. PMID: 24336114 |
Ref: Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer. PMID: 24346863 Ref: Interference of Skp2 effectively inhibits the development and metastasis of colon carcinoma. PMID: 24913024 |
Ref: microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs. PMID: 25826661 |
Ref: Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis. PMID: 25808857 Ref: [Corrigendum] Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells. PMID: 26718100 Ref: Physical Activity and Cancer Outcomes: A Precision Medicine Approach. PMID: 27407093 |
Ref: The prognostic role of Skp2 and the tumor suppressor protein p27 in colorectal cancer. PMID: 29135092 Ref: Therapeutic inhibition of SGK1 suppresses colorectal cancer. PMID: 29170478 |
Ref: Tumor Suppressive Role of ARHGAP17 in Colon Cancer Through Wnt/beta-Catenin Signaling. PMID: 29730655 Ref: Increased EZH2 expression during the adenoma-carcinoma sequence in colorectal cancer. PMID: 30214616 |