Literatures

Primary Site >> Pancreatic Cancer

Gene >> SRC

1.
Journal:	Biochem Biophys Res Commun. 1998 Feb 13;243(2):503-8.
Title:	Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma.
Author:	Lutz, M P\|Esser, I B\|Flossmann-Kast, B B\|Vogelmann, R\|Luhrs, H\|Friess, H\|Buchler, M W\|Adler, G
PMID:	9480838

2.
Journal:	Cancer Res. 1998 Aug 15;58(16):3551-4.
Title:	Src stimulates insulin-like growth factor I (IGF-I)-dependent cell proliferation by increasing IGF-I receptor number in human pancreatic carcinoma cells.
Author:	Flossmann-Kast, B B\|Jehle, P M\|Hoeflich, A\|Adler, G\|Lutz, M P
PMID:	9721859

3.
Journal:	Cancer Res. 2001 Jan 15;61(2):589-93.
Title:	AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.
Author:	Tanno, S\|Tanno, S\|Mitsuuchi, Y\|Altomare, D A\|Xiao, G H\|Testa, J R
PMID:	11212254

4.
Journal:	Ann Oncol. 2001;12 Suppl 2:S13-7.
Title:	Oncogenes, growth factors, receptor expression and proliferation markers in digestive neuroendocrine tumours. A critical reappraisal.
Author:	Delle Fave, G\|Corleto, V D
PMID:	11762339

5.
Journal:	Biochem Biophys Res Commun. 2003 Feb 28;302(1):46-55.
Title:	Requirement of different signaling pathways mediated by insulin-like growth factor-I receptor for proliferation, invasion, and VPF/VEGF expression in a pancreatic carcinoma cell line.
Author:	Zeng, Huiyan\|Datta, Kaustubh\|Neid, Matthias\|Li, Jinping\|Parangi, Sareh\|Mukhopadhyay, Debabrata
PMID:	12593846

6.
Journal:	Cancer Res. 2003 May 15;63(10):2379-87.
Title:	Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.
Author:	Guha, Sushovan\|Lunn, J Adrian\|Santiskulvong, Chintda\|Rozengurt, Enrique
PMID:	12750255

7.
Journal:	J Biol Chem. 2003 Sep 26;278(39):38029-39. Epub 2003 Jun 27.
Title:	Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.
Author:	Wen, Yunfei\|Caffrey, Thomas C\|Wheelock, Margaret J\|Johnson, Keith R\|Hollingsworth, Michael A
PMID:	12832415

8.
Journal:	Cancer Metastasis Rev. 2003 Dec;22(4):337-58.
Title:	Src family kinases in tumor progression and metastasis.
Author:	Summy, Justin M\|Gallick, Gary E
PMID:	12884910

9.
Journal:	Surgery. 2003 Aug;134(2):221-6.
Title:	Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness.
Author:	Ito, Hiromichi\|Gardner-Thorpe, James\|Zinner, Michael J\|Ashley, Stanley W\|Whang, Edward E
PMID:	12947321

10.
Journal:	Dig Dis Sci. 2003 Oct;48(10):1972-8.
Title:	Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma.
Author:	Hakam, Ardeshir\|Fang, Quan\|Karl, Richard\|Coppola, Domenico
PMID:	14627343

11.
Journal:	Int J Mol Med. 2004 Mar;13(3):473-8.
Title:	Identification and characterization of human DIAPH3 gene in silico.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	14767582

12.
Journal:	J Biol Chem. 2004 Sep 24;279(39):40400-4. Epub 2004 Jul 29.
Title:	Agonist-independent activation of Src tyrosine kinase by a cholecystokinin-2 (CCK2) receptor splice variant.
Author:	Olszewska-Pazdrak, Barbara\|Townsend, Courtney M Jr\|Hellmich, Mark R
PMID:	15292208

13.
Journal:	Clin Cancer Res. 2004 Dec 1;10(23):8028-36.
Title:	Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice.
Author:	Yezhelyev, Maksim V\|Koehl, Gudrun\|Guba, Markus\|Brabletz, Thomas\|Jauch, Karl-Walter\|Ryan, Anderson\|Barge, Alan\|Green, Tim\|Fennell, Michael\|Bruns, Christiane J
PMID:	15585638

14.
Journal:	Cancer Res. 2005 Aug 15;65(16):7214-22.
Title:	Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.
Author:	Trevino, Jose G\|Summy, Justin M\|Gray, Michael J\|Nilsson, Monique B\|Lesslie, Donald P\|Baker, Cheryl H\|Gallick, Gary E
PMID:	16103072

15.
Journal:	Pancreas. 2005 Oct;31(3):263-74.
Title:	c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK.
Author:	Summy, Justin M\|Trevino, Jose G\|Baker, Cheryl H\|Gallick, Gary E
PMID:	16163059

16.
Journal:	Mol Cancer Ther. 2005 Dec;4(12):1900-11.
Title:	AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes.
Author:	Summy, Justin M\|Trevino, Jose G\|Lesslie, Donald P\|Baker, Cheryl H\|Shakespeare, William C\|Wang, Yihan\|Sundaramoorthi, Raji\|Metcalf, Chester A 3rd\|Keats, Jeffrey A\|Sawyer, Tomi K\|Gallick, Gary E
PMID:	16373705

17.
Journal:	J Biol Chem. 2006 Feb 24;281(8):4570-9.
Title:	Epithelial growth factor-induced phosphorylation of caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells.
Author:	Orlichenko, Lidiya\|Huang, Bing\|Krueger, Eugene\|McNiven, Mark A
PMID:	16332692

18.
Journal:	Am J Pathol. 2006 Mar;168(3):962-72.
Title:	Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.
Author:	Trevino, Jose G\|Summy, Justin M\|Lesslie, Donald P\|Parikh, Nila U\|Hong, David S\|Lee, Francis Y\|Donato, Nicholas J\|Abbruzzese, James L\|Baker, Cheryl H\|Gallick, Gary E
PMID:	16507911

19.
Journal:	Mol Cancer Ther. 2006 Mar;5(3):621-9.
Title:	Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.
Author:	Kotha, Anupama\|Sekharam, Madhavi\|Cilenti, Lucia\|Siddiquee, Khandaker\|Khaled, Annette\|Zervos, Antonis S\|Carter, Bradford\|Turkson, James\|Jove, Richard
PMID:	16546976

20.
Journal:	Drug Resist Updat. 2006 Feb-Apr;9(1-2):1-18. Epub 2006 Apr 18.
Title:	Tyrosine kinase inhibitors and gemcitabine: new treatment options in pancreatic cancer?
Author:	Kleespies, Axel\|Jauch, Karl-Walter\|Bruns, Christiane J
PMID:	16621676

21.
Journal:	Int J Oncol. 2006 Jul;29(1):125-38.
Title:	Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice.
Author:	Baker, Cheryl H\|Trevino, Jose G\|Summy, Justin M\|Zhang, Fahao\|Caron, Alexis\|Nesbit, Mark\|Gallick, Gary E\|Fidler, Isaiah J
PMID:	16773192

22.
Journal:	Angiogenesis. 2006;9(2):101-10. Epub 2006 Jul 27.
Title:	Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells.
Author:	Trevino, Jose G\|Gray, Michael J\|Nawrocki, Steffan T\|Summy, Justin M\|Lesslie, Donald P\|Evans, Douglas B\|Sawyer, Tomi K\|Shakespeare, William C\|Watowich, Stephanie S\|Chiao, Paul J\|McConkey, David J\|Gallick, Gary E
PMID:	16871430

23.
Journal:	World J Gastroenterol. 2006 Jul 28;12(28):4498-503.
Title:	Mechanism for Src activation by the CCK2 receptor: Patho-physiological functions of this receptor in pancreas.
Author:	Ferrand, Audrey\|Vatinel, Sebastien\|Kowalski-Chauvel, Aline\|Bertrand, Claudine\|Escrieut, Chantal\|Fourmy, Daniel\|Dufresne, Marlene\|Seva, Catherine
PMID:	16874861

24.
Journal:	J Med Chem. 2006 Nov 2;49(22):6465-88.
Title:	N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor.
Author:	Hennequin, Laurent F\|Allen, Jack\|Breed, Jason\|Curwen, Jon\|Fennell, Michael\|Green, Tim P\|Lambert-van der Brempt, Christine\|Morgentin, Remy\|Norman, Richard A\|Olivier, Annie\|Otterbein, Ludovic\|Ple, Patrick A\|Warin, Nicolas\|Costello, Gerard
PMID:	17064066

25.
Journal:	Int J Gastrointest Cancer. 2006;37(4):110-9.
Title:	Characterization of the CXCR4 signaling in pancreatic cancer cells.
Author:	Billadeau, Daniel D\|Chatterjee, Subrha\|Bramati, Patricia\|Sreekumar, Raghavakaimal\|Shah, Vijay\|Hedin, Karen\|Urrutia, Raul
PMID:	18175225

26.
Journal:	Cancer Lett. 2007 Jan 8;245(1-2):242-51. Epub 2006 Mar 15.
Title:	Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors).
Author:	Hirokawa, Yumiko\|Levitzki, Alexander\|Lessene, Guillaume\|Baell, Jonathan\|Xiao, Yi\|Zhu, Hongjian\|Maruta, Hiroshi
PMID:	16540233

27.
Journal:	Oncogene. 2007 Oct 18;26(48):6851-62. Epub 2007 Apr 30.
Title:	Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of caveolin-1.
Author:	Cordes, N\|Frick, S\|Brunner, T B\|Pilarsky, C\|Grutzmann, R\|Sipos, B\|Kloppel, G\|McKenna, W G\|Bernhard, E J
PMID:	17471232

28.
Journal:	Angiogenesis. 2007;10(3):167-82.
Title:	Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer.
Author:	Ischenko, Ivan\|Guba, Markus\|Yezhelyev, Maksim\|Papyan, Armine\|Schmid, Gerald\|Green, Tim\|Fennell, Michael\|Jauch, Karl-Walter\|Bruns, Christiane J
PMID:	17486419

29.
Journal:	Cancer Res. 2007 Nov 1;67(21):10309-16.
Title:	Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1.
Author:	Matsushita, Arikira\|Gotze, Tobias\|Korc, Murray
PMID:	17974973

30.
Journal:	Anticancer Agents Med Chem. 2007 Nov;7(6):651-9.
Title:	SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy.
Author:	Johnson, Faye M\|Gallick, Gary E
PMID:	18045060

31.
Journal:	Cancer Lett. 2008 Feb 18;260(1-2):155-62. Epub 2007 Dec 19.
Title:	Inhibition of Src reduces gemcitabine-induced cytotoxicity in human pancreatic cancer cell lines.
Author:	Ichihara, Naoto\|Kubota, Yoshitsugu\|Kitanaka, Akira\|Tanaka, Terukazu\|Taminato, Tomohiko
PMID:	18078709

32.
Journal:	Recent Results Cancer Res. 2008;177:179-85.
Title:	Src kinase and pancreatic cancer.
Author:	Hilbig, A
PMID:	18084959

33.
Journal:	Curr Med Chem. 2008;15(10):978-90.
Title:	ANTI-ADHESION evolves to a promising therapeutic concept in oncology.
Author:	Schmidmaier, R\|Baumann, P
PMID:	18393855

34.
Journal:	Oncogene. 2008 Dec 4;27(57):7212-22.
Title:	Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling.
Author:	Ischenko, I\|Camaj, P\|Seeliger, H\|Kleespies, A\|Guba, M\|De Toni, E N\|Schwarz, B\|Graeb, C\|Eichhorn, M E\|Jauch, K-W\|Bruns, C J
PMID:	18794807

35.
Journal:	Br J Cancer. 2008 Oct 7;99(7):1074-82.
Title:	Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.
Author:	Chang, Q\|Jorgensen, C\|Pawson, T\|Hedley, D W
PMID:	18797457

36.
Journal:	Expert Rev Gastroenterol Hepatol. 2008 Oct;2(5):673-96.
Title:	New treatment options for advanced pancreatic cancer.
Author:	Middleton, Gary\|Ghaneh, Paula\|Costello, Eithne\|Greenhalf, William\|Neoptolemos, John P
PMID:	19072345

37.
Journal:	Biologics. 2008 Dec;2(4):707-15.
Title:	Small molecule tyrosine kinase inhibitors in pancreatic cancer.
Author:	Gupta, Sachin\|El-Rayes, Bassel F
PMID:	19707451

38.
Journal:	Int J Cancer. 2009 Jan 15;124(2):280-6.
Title:	Activation of Src and Src-associated signaling pathways in relation to hypoxia in human cancer xenograft models.
Author:	Pham, Nhu-An\|Magalhaes, Joao M M M\|Do, Trevor\|Schwock, Joerg\|Dhani, Neesha\|Cao, Ping-Jiang\|Hill, Richard P\|Hedley, David W
PMID:	18924149

39.
Journal:	Biochem Biophys Res Commun. 2009 Feb 6;379(2):445-50.
Title:	EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2.
Author:	Binker, Marcelo G\|Binker-Cosen, Andres A\|Richards, Daniel\|Oliver, Brenda\|Cosen-Binker, Laura I
PMID:	19116140

40.
Journal:	Cancer Res. 2009 Feb 15;69(4):1383-91.
Title:	Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis.
Author:	Ricono, Jill M\|Huang, Miller\|Barnes, Leo A\|Lau, Steven K\|Weis, Sara M\|Schlaepfer, David D\|Hanks, Steven K\|Cheresh, David A
PMID:	19208836

41.
Journal:	Cancer Sci. 2009 Apr;100(4):770-7.
Title:	Phosphoinositide 3-kinase inhibitor (wortmannin) inhibits pancreatic cancer cell motility and migration induced by hyaluronan in vitro and peritoneal metastasis in vivo.
Author:	Teranishi, Futoshi\|Takahashi, Naoko\|Gao, Nan\|Akamo, Yoshimi\|Takeyama, Hiromitsu\|Manabe, Tadao\|Okamoto, Takashi
PMID:	19469020

42.
Journal:	Clin Cancer Res. 2009 Jun 15;15(12):4138-46.
Title:	Antitumor effects and biomarkers of activity of AZD0530, a Src inhibitor, in pancreatic cancer.
Author:	Rajeshkumar, N V\|Tan, Aik Choon\|De Oliveira, Elizabeth\|Womack, Chris\|Wombwell, Helen\|Morgan, Shethah\|Warren, Madhuri V\|Walker, Jill\|Green, Tim P\|Jimeno, Antonio\|Messersmith, Wells A\|Hidalgo, Manuel
PMID:	19509160

43.
Journal:	Mol Cancer Ther. 2009 Jun;8(6):1484-93.
Title:	Efficacy and pharmacodynamic effects of bosutinib (SKI-606), a Src/Abl inhibitor, in freshly generated human pancreas cancer xenografts.
Author:	Messersmith, Wells A\|Rajeshkumar, N V\|Tan, Aik Choon\|Wang, Xiao Fei\|Diesl, Veronica\|Choe, Sung E\|Follettie, Max\|Coughlin, Christina\|Boschelli, Frank\|Garcia-Garcia, Elena\|Lopez-Rios, Fernando\|Jimeno, Antonio\|Hidalgo, Manuel
PMID:	19509264

44.
Journal:	Nat Med. 2009 Oct;15(10):1163-9.
Title:	An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression.
Author:	Desgrosellier, Jay S\|Barnes, Leo A\|Shields, David J\|Huang, Miller\|Lau, Steven K\|Prevost, Nicolas\|Tarin, David\|Shattil, Sanford J\|Cheresh, David A
PMID:	19734908

45.
Journal:	Biochem Pharmacol. 2010 May 15;79(10):1398-409.
Title:	A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.
Author:	Zhang, Xiaolei\|Yue, Peibin\|Fletcher, Steven\|Zhao, Wei\|Gunning, Patrick T\|Turkson, James
PMID:	20067773

46.
Journal:	J Pharmacol Exp Ther. 2010 May;333(2):373-81.
Title:	Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.
Author:	Jaganathan, Soumya\|Yue, Peibin\|Turkson, James
PMID:	20100905

47.
Journal:	JOP. 2010 Mar 5;11(2):151-3.
Title:	Any second-line therapy for advanced pancreatic cancer? Highlights from the "2010 ASCO Gastrointestinal Cancers Symposium". Orlando, FL, USA. January 22-24, 2010.
Author:	Li, Jia\|Merl, Man Yee\|Saif, Muhammad Wasif
PMID:	20208325

48.
Journal:	PLoS One. 2010 Mar 4;5(3):e9430.
Title:	Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model.
Author:	Humbert, Martine\|Casteran, Nathalie\|Letard, Sebastien\|Hanssens, Katia\|Iovanna, Juan\|Finetti, Pascal\|Bertucci, Francois\|Bader, Thomas\|Mansfield, Colin D\|Moussy, Alain\|Hermine, Olivier\|Dubreuil, Patrice
PMID:	20209107

49.
Journal:	Curr Cancer Drug Targets. 2010 Aug;10(5):546-53.
Title:	Src tyrosine kinase inhibition suppresses lymphangiogenesis in vitro and in vivo.
Author:	Ischenko, I\|Seeliger, H\|Camaj, P\|Kleespies, A\|Guba, M\|Eichhorn, M E\|Jauch, K-W\|Bruns, C J
PMID:	20370688

50.
Journal:	J Biol Chem. 2010 Jul 23;285(30):23075-85.
Title:	Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.
Author:	Lazer, Galit\|Pe'er, Liron\|Farago, Marganit\|Machida, Kazuya\|Mayer, Bruce J\|Katzav, Shulamit
PMID:	20457609

51.
Journal:	Ann Surg Oncol. 2010 Oct;17(10):2619-27.
Title:	Higher expression of the heterogeneous nuclear ribonucleoprotein k in melanoma.
Author:	Wen, Fushi\|Shen, Alex\|Shanas, Renee\|Bhattacharyya, Achyut\|Lian, Fangru\|Hostetter, Galen\|Shi, Jiaqi
PMID:	20499280

52.
Journal:	Mol Cancer Ther. 2010 Aug;9(8):2322-32.
Title:	Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis.
Author:	Nagaraj, Nagathihalli S\|Smith, J Joshua\|Revetta, Frank\|Washington, M Kay\|Merchant, Nipun B
PMID:	20682659

53.
Journal:	Mol Carcinog. 2010 Dec;49(12):1007-21.
Title:	Loss of tyrosine phosphatase-dependent inhibition promotes activation of tyrosine kinase c-Src in detached pancreatic cells.
Author:	Connelly, Sarah F\|Isley, Beth A\|Baker, Cheryl H\|Gallick, Gary E\|Summy, Justin M
PMID:	20945416

54.
Journal:	Front Biosci (Elite Ed). 2011 Jan 1;3:750-6.
Title:	Focal adhesion kinase signaling and function in pancreatic cancer.
Author:	Ucar, Deniz A\|Dang, Long H\|Hochwald, Steven N
PMID:	21196348

55.
Journal:	Oncogene. 2011 May 5;30(18):2123-34.
Title:	Oncogenic Ras/Src cooperativity in pancreatic neoplasia.
Author:	Shields, D J\|Murphy, E A\|Desgrosellier, J S\|Mielgo, A\|Lau, S K M\|Barnes, L A\|Lesperance, J\|Huang, M\|Schmedt, C\|Tarin, D\|Lowy, A M\|Cheresh, D A
PMID:	21242978

56.
Journal:	Clin Cancer Res. 2011 Feb 1;17(3):483-93.
Title:	Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth.
Author:	Nagaraj, Nagathihalli S\|Washington, M Kay\|Merchant, Nipun B
PMID:	21266529

57.
Journal:	Transl Oncol. 2011 Apr 1;4(2):83-91.
Title:	Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer.
Author:	Yokoi, Kenji\|Hawke, David\|Oborn, Carol J\|Jang, Jin-Young\|Nishioka, Yasuhiko\|Fan, Dominic\|Kim, Seung Wook\|Kim, Sun-Jin\|Fidler, Isaiah J
PMID:	21461171

58.
Journal:	PLoS One. 2011 May 5;6(5):e19605.
Title:	A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.
Author:	Jaganathan, Soumya\|Yue, Peibin\|Paladino, David C\|Bogdanovic, Jelena\|Huo, Qun\|Turkson, James
PMID:	21573184

59.
Journal:	J Biol Chem. 2011 Jul 15;286(28):24776-84.
Title:	Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK).
Author:	Yuan, Kaiyu\|Jing, Gu\|Chen, Jianfeng\|Liu, Hui\|Zhang, Kui\|Li, Yuebin\|Wu, Hui\|McDonald, Jay M\|Chen, Yabing
PMID:	21613217

60.
Journal:	Mol Cancer Ther. 2011 Nov;10(11):2083-93.
Title:	Digitoxin-induced cytotoxicity in cancer cells is mediated through distinct kinase and interferon signaling networks.
Author:	Prassas, Ioannis\|Karagiannis, George S\|Batruch, Ihor\|Dimitromanolakis, Apostolos\|Datti, Alessandro\|Diamandis, Eleftherios P
PMID:	21859838

61.
Journal:	Oncology. 2011;81(3-4):259-72.
Title:	Molecular pathogenesis of pancreatic cancer and clinical perspectives.
Author:	Matthaios, D\|Zarogoulidis, P\|Balgouranidou, I\|Chatzaki, E\|Kakolyris, S
PMID:	22116519

62.
Journal:	Invest New Drugs. 2012 Apr;30(2):779-86.
Title:	A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer.
Author:	Renouf, Daniel J\|Moore, Malcolm J\|Hedley, David\|Gill, Sharlene\|Jonker, Derek\|Chen, Eric\|Walde, David\|Goel, Rakesh\|Southwood, Bernadette\|Gauthier, Isabelle\|Walsh, Wendy\|McIntosh, Lynn\|Seymour, Lesley
PMID:	21170669

63.
Journal:	Oncogene. 2012 Mar 8;31(10):1228-41.
Title:	Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma.
Author:	Eppinga, R D\|Krueger, E W\|Weller, S G\|Zhang, L\|Cao, H\|McNiven, M A
PMID:	21841817

64.
Journal:	Oncogene. 2012 May 31;31(22):2783-93.
Title:	EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation.
Author:	Huang, M\|Anand, S\|Murphy, E A\|Desgrosellier, J S\|Stupack, D G\|Shattil, S J\|Schlaepfer, D D\|Cheresh, D A
PMID:	21963850

65.
Journal:	Mol Cell Biochem. 2012 Mar;362(1-2):65-70.
Title:	The non-receptor tyrosine kinase c-Src mediates the PDGF-induced association between Furin and pro-MT1-MMP in HPAC pancreatic cells.
Author:	Shi, Chong\|Ma, Yongchao\|Liu, Hao\|Zhang, Yuxiang\|Wang, Zesheng\|Jia, Hongti
PMID:	22038627

66.
Journal:	Carcinogenesis. 2012 Jan;33(1):191-6.
Title:	Regulation of pancreatic cancer by neuropsychological stress responses: a novel target for intervention.
Author:	Schuller, Hildegard M\|Al-Wadei, Hussein A N\|Ullah, Mohammad F\|Plummer, Howard K 3rd
PMID:	22072614

67.
Journal:	Mol Cancer Res. 2012 Feb;10(2):239-49.
Title:	Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors alpha3, alpha5, and alpha7.
Author:	Al-Wadei, Mohammed H\|Al-Wadei, Hussein A N\|Schuller, Hildegard M
PMID:	22188668

68.
Journal:	Oncol Rep. 2012 Mar;27(3):628-36.
Title:	A study of the suppressive effect on human pancreatic adenocarcinoma cell proliferation and angiogenesis by stable plasmid-based siRNA silencing of c-Src gene expression.
Author:	Zhao, Xin\|Li, De-Chun\|Zhao, Hua\|Li, Zhi\|Wang, Jian-Xin\|Zhu, Dong-Ming\|Zhou, Jin\|Cen, Jian-Nong
PMID:	22200682

69.
Journal:	Carcinogenesis. 2012 Mar;33(3):555-62.
Title:	DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activating SRC/ERK/uPA.
Author:	He, Xiangyi\|Zheng, Zhong\|Li, Jianfang\|Ben, Qiwen\|Liu, Jun\|Zhang, Jianian\|Ji, Jun\|Yu, Beiqin\|Chen, Xuehua\|Su, Liping\|Zhou, Lin\|Liu, Bingya\|Yuan, Yaozong
PMID:	22223849

70.
Journal:	Mol Cancer. 2012 Apr 3;11:19.
Title:	Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype.
Author:	De Oliveira, Tiago\|Abiatari, Ivane\|Raulefs, Susanne\|Sauliunaite, Danguole\|Erkan, Mert\|Kong, Bo\|Friess, Helmut\|Michalski, Christoph W\|Kleeff, Jorg
PMID:	22471946

71.
Journal:	PLoS One. 2012;7(3):e33414.
Title:	The tyrosine kinase c-Src directly mediates growth factor-induced Notch-1 and Furin interaction and Notch-1 activation in pancreatic cancer cells.
Author:	Ma, Yong-Chao\|Shi, Chong\|Zhang, Yao-Nan\|Wang, Lan-Ge\|Liu, Hao\|Jia, Hong-Ti\|Zhang, Yu-Xiang\|Sarkar, Fazlul H\|Wang, Ze-Sheng
PMID:	22479394

72.
Journal:	Mol Cancer. 2012 Apr 26;11:24.
Title:	Nicotine, IFN-gamma and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades.
Author:	Kunigal, Sateesh\|Ponnusamy, Moorthy P\|Momi, Navneet\|Batra, Surinder K\|Chellappan, Srikumar P
PMID:	22537161

73.
Journal:	Cancer Res. 2012 May 15;72(10):2554-64.
Title:	KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.
Author:	Kelber, Jonathan A\|Reno, Theresa\|Kaushal, Sharmeela\|Metildi, Cristina\|Wright, Tracy\|Stoletov, Konstantin\|Weems, Jessica M\|Park, Frederick D\|Mose, Evangeline\|Wang, Yingchun\|Hoffman, Robert M\|Lowy, Andrew M\|Bouvet, Michael\|Klemke, Richard L
PMID:	22589274

74.
Journal:	Front Biosci (Landmark Ed). 2012 Jun 1;17:2059-69.
Title:	Src-mediated regulation of E-cadherin and EMT in pancreatic cancer.
Author:	Nagathihalli, Nagaraj S\|Merchant, Nipun B
PMID:	22652764

75.
Journal:	Cell Mol Life Sci. 2012 Nov;69(22):3863-79.
Title:	CD24 controls Src/STAT3 activity in human tumors.
Author:	Bretz, Niko P\|Salnikov, Alexei V\|Perne, Claudia\|Keller, Sascha\|Wang, Xiaoli\|Mierke, Claudia T\|Fogel, Mina\|Erbe-Hofmann, Natalie\|Schlange, Thomas\|Moldenhauer, Gerhard\|Altevogt, Peter
PMID:	22760497

76.
Journal:	PLoS One. 2012;7(6):e39684.
Title:	Concomitant targeting of EGF receptor, TGF-beta and SRC points to a novel therapeutic approach in pancreatic cancer.
Author:	Deharvengt, Sophie\|Marmarelis, Melina\|Korc, Murray
PMID:	22761868

77.
Journal:	Carcinogenesis. 2012 Sep;33(9):1745-53.
Title:	Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters.
Author:	Al-Wadei, Mohammed H\|Al-Wadei, Hussein A N\|Schuller, Hildegard M
PMID:	22791813

78.
Journal:	PLoS One. 2012;7(8):e43376.
Title:	Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice.
Author:	Al-Wadei, Hussein A N\|Al-Wadei, Mohammed H\|Ullah, Mohammad F\|Schuller, Hildegard M
PMID:	22916251

79.
Journal:	Cancer Genet. 2012 Nov;205(11):552-62.
Title:	Ror2-Src signaling in metastasis of mouse melanoma cells is inhibited by NRAGE.
Author:	Lai, Shan-Shan\|Xue, Bin\|Yang, Yang\|Zhao, Li\|Chu, Chao-Shun\|Hao, Jia-Yin\|Wen, Chuan-Jun
PMID:	23142633

80.
Journal:	Neoplasia. 2012 Dec;14(12):1102-14.
Title:	Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma.
Author:	Trevino, Jose G\|Pillai, Smitha\|Kunigal, Sateesh\|Singh, Sandeep\|Fulp, William J\|Centeno, Barbara A\|Chellappan, Srikumar P
PMID:	23308043

81.
Journal:	Cancer Med. 2012 Oct;1(2):207-17.
Title:	Biomarker-driven trial in metastatic pancreas cancer: feasibility in a multicenter study of saracatinib, an oral Src inhibitor, in previously treated pancreatic cancer.
Author:	Arcaroli, John\|Quackenbush, Kevin\|Dasari, Arvind\|Powell, Rebecca\|McManus, Martine\|Tan, Aik-Choon\|Foster, Nathan R\|Picus, Joel\|Wright, John\|Nallapareddy, Sujatha\|Erlichman, Charles\|Hidalgo, Manuel\|Messersmith, Wells A
PMID:	23342270

82.
Journal:	Eur J Cancer. 2013 Mar;49(5):1152-8.
Title:	Chronic nicotine inhibits the therapeutic effects of gemcitabine on pancreatic cancer in vitro and in mouse xenografts.
Author:	Banerjee, Jheelam\|Al-Wadei, Hussein A N\|Schuller, Hildegard M
PMID:	23146955

83.
Journal:	Mol Oncol. 2013 Jun;7(3):369-78.
Title:	Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.
Author:	Nam, Sangkil\|Wen, Wei\|Schroeder, Anne\|Herrmann, Andreas\|Yu, Hua\|Cheng, Xinlai\|Merz, Karl-Heinz\|Eisenbrand, Gerhard\|Li, Hongzhi\|Yuan, Yate-Ching\|Jove, Richard
PMID:	23206899

84.
Journal:	Carcinogenesis. 2013 Mar;34(3):694-702.
Title:	Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells.
Author:	Park, Eun Hye\|Kim, Seokho\|Jo, Ji Yoon\|Kim, Su Jin\|Hwang, Yeonsil\|Kim, Jin-Man\|Song, Si Young\|Lee, Dong-Ki\|Koh, Sang Seok
PMID:	23222813

85.
Journal:	Pancreas. 2013 Jul;42(5):795-806.
Title:	Targeting the yin and the yang: combined inhibition of the tyrosine kinase c-Src and the tyrosine phosphatase SHP-2 disrupts pancreatic cancer signaling and biology in vitro and tumor formation in vivo.
Author:	Gomes, Evan G\|Connelly, Sarah F\|Summy, Justin M
PMID:	23271399

86.
Journal:	Invest New Drugs. 2013 Aug;31(4):967-73.
Title:	A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies.
Author:	Naing, Aung\|Cohen, Roger\|Dy, Grace K\|Hong, David S\|Dyster, Lyn\|Hangauer, David G\|Kwan, Rudolf\|Fetterly, Gerald\|Kurzrock, Razelle\|Adjei, Alex A
PMID:	23361621

87.
Journal:	PLoS One. 2013 May 1;8(5):e61532.
Title:	Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice.
Author:	Mackenzie, Gerardo G\|Huang, Liqun\|Alston, Ninche\|Ouyang, Nengtai\|Vrankova, Kvetoslava\|Mattheolabakis, George\|Constantinides, Panayiotis P\|Rigas, Basil
PMID:	23650499

88.
Journal:	Cancer Res. 2013 Aug 1;73(15):4674-86.
Title:	Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer.
Author:	Nobis, Max\|McGhee, Ewan J\|Morton, Jennifer P\|Schwarz, Juliane P\|Karim, Saadia A\|Quinn, Jean\|Edward, Mike\|Campbell, Andrew D\|McGarry, Lynn C\|Evans, T R Jeffry\|Brunton, Valerie G\|Frame, Margaret C\|Carragher, Neil O\|Wang, Yingxiao\|Sansom, Owen J\|Timpson, Pau
PMID:	23749641

89.
Journal:	J Thromb Haemost. 2013 Oct;11(10):1892-902.
Title:	Protease-activated receptor-2 induces migration of pancreatic cancer cells in an extracellular ATP-dependent manner.
Author:	Shi, K\|Queiroz, K C S\|Stap, J\|Richel, D J\|Spek, C A
PMID:	23899344

90.
Journal:	Cancer Lett. 2013 Dec 1;341(2):166-77.
Title:	Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.
Author:	Macha, Muzafar A\|Rachagani, Satyanarayana\|Gupta, Suprit\|Pai, Priya\|Ponnusamy, Moorthy P\|Batra, Surinder K\|Jain, Maneesh
PMID:	23920124

91.
Journal:	PLoS One. 2013 Dec 5;8(12):e79654.
Title:	Quantitative proteomic profiling identifies DPYSL3 as pancreatic ductal adenocarcinoma-associated molecule that regulates cell adhesion and migration by stabilization of focal adhesion complex.
Author:	Kawahara, Takeo\|Hotta, Naoe\|Ozawa, Yukiko\|Kato, Seiichi\|Kano, Keiko\|Yokoyama, Yukihiro\|Nagino, Masato\|Takahashi, Takashi\|Yanagisawa, Kiyoshi
PMID:	24339867

92.
Journal:	Curr Biol. 2014 Jan 6;24(1):86-93.
Title:	Vav1 as a central regulator of invadopodia assembly.
Author:	Razidlo, Gina L\|Schroeder, Barbara\|Chen, Jing\|Billadeau, Daniel D\|McNiven, Mark A
PMID:	24332539

93.
Journal:	J Clin Invest. 2014 Jan;124(1):338-52.
Title:	Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-beta to promote proliferation.
Author:	Gore, A Jesse\|Deitz, Samantha L\|Palam, Lakshmi Reddy\|Craven, Kelly E\|Korc, Murray
PMID:	24334458

94.
Journal:	Oncologist. 2014 Feb;19(2):211.
Title:	Src inhibition is still a relevant target in pancreatic cancer.
Author:	George, Thomas J Jr\|Trevino, Jose G\|Liu, Chen
PMID:	24457377

95.
Journal:	Mol Cancer. 2014 Jan 27;13:15.
Title:	CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis.
Author:	Ding, Qiang\|Miyazaki, Yumi\|Tsukasa, Koichiro\|Matsubara, Shyuichiro\|Yoshimitsu, Makoto\|Takao, Sonshin
PMID:	24468059

96.
Journal:	Int J Oncol. 2014 Jun;44(6):2132-8.
Title:	Combination of dasatinib and gemcitabine reduces the ALDH1A1 expression and the proliferation of gemcitabine-resistant pancreatic cancer MIA PaCa-2 cells.
Author:	Duong, Hong-Quan\|Yi, Yong Weon\|Kang, Hyo Jin\|Bae, Insoo\|Jang, Young-Joo\|Kwak, Sahng-June\|Seong, Yeon-Sun
PMID:	24676703

97.
Journal:	Pancreas. 2014 Jul;43(5):768-76.
Title:	The inhibition of SRC family kinase suppresses pancreatic cancer cell proliferation, migration, and invasion.
Author:	Je, Dong Wook\|O, Young Moon\|Ji, Young Geon\|Cho, Yunkyung\|Lee, Dong Hyeon
PMID:	24763074

98.
Journal:	Cell Cycle. 2014;13(14):2172-91.
Title:	Re-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpoints.
Author:	Beeharry, Neil\|Banina, Eugenia\|Hittle, James\|Skobeleva, Natalia\|Khazak, Vladimir\|Deacon, Sean\|Andrake, Mark\|Egleston, Brian L\|Peterson, Jeffrey R\|Astsaturov, Igor\|Yen, Timothy J
PMID:	24955955

99.
Journal:	PLoS One. 2014 Aug 29;9(8):e105245.
Title:	Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
Author:	Gurbuz, Nilgun\|Ashour, Ahmed A\|Alpay, S Neslihan\|Ozpolat, Bulent
PMID:	25170871

100.
Journal:	J Cell Mol Med. 2014 Nov;18(11):2235-51.
Title:	Elongation factor-2 kinase regulates TG2/beta1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasion.
Author:	Ashour, Ahmed A\|Gurbuz, Nilgun\|Alpay, Sultan Neslihan\|Abdel-Aziz, Abdel-Aziz H\|Mansour, Ahmed M\|Huo, Longfei\|Ozpolat, Bulent
PMID:	25215932

101.
Journal:	PLoS One. 2014 Sep 30;9(9):e110067.
Title:	Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
Author:	Gurbuz, Nilgun\|Ashour, Ahmed A\|Alpay, S Neslihan\|Ozpolat, Bulent
PMID:	25268648

102.
Journal:	Cell Adh Migr. 2014;8(5):478-86.
Title:	Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging.
Author:	Nobis, Max\|McGhee, Ewan J\|Herrmann, David\|Magenau, Astrid\|Morton, Jennifer P\|Anderson, Kurt I\|Timpson, Paul
PMID:	25482620

103.
Journal:	Br J Pharmacol. 2015 Jan;172(1):50-63.
Title:	Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells.
Author:	Pathania, Divya\|Kuang, Yuting\|Sechi, Mario\|Neamati, Nouri
PMID:	25047070

104.
Journal:	Mol Cancer Ther. 2015 Feb;14(2):407-18.
Title:	A preclinical evaluation of SKLB261, a multikinase inhibitor of EGFR/Src/VEGFR2, as a therapeutic agent against pancreatic cancer.
Author:	Pan, Youli\|Zheng, Mingwu\|Zhong, Lei\|Yang, Jiao\|Zhou, Shu\|Qin, Ya\|Xiang, Rong\|Chen, Yuzong\|Yang, Sheng-Yong
PMID:	25519702

105.
Journal:	Mol Pharmacol. 2015;87(3):543-60.
Title:	Novel thiosemicarbazones regulate the signal transducer and activator of transcription 3 (STAT3) pathway: inhibition of constitutive and interleukin 6-induced activation by iron depletion.
Author:	Lui, Goldie Y L\|Kovacevic, Zaklina\|V Menezes, Sharleen\|Kalinowski, Danuta S\|Merlot, Angelica M\|Sahni, Sumit\|Richardson, Des R
PMID:	25561562

106.
Journal:	J Hepatobiliary Pancreat Sci. 2015 Aug;22(8):594-601.
Title:	Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendocrine tumors.
Author:	Capurso, Gabriele\|Archibugi, Livia\|Delle Fave, Gianfranco
PMID:	25619712

107.
Journal:	Sci Rep. 2015 Feb 13;5:8453.
Title:	S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase.
Author:	Che, Pulin\|Yang, Youfeng\|Han, Xiaosi\|Hu, Meng\|Sellers, Jeffery C\|Londono-Joshi, Angelina I\|Cai, Guo-Qiang\|Buchsbaum, Donald J\|Christein, John D\|Tang, Qinjiu\|Chen, Dongquan\|Li, Qianjun\|Grizzle, William E\|Lu, Yin Ying\|Ding, Qiang
PMID:	25677816

108.
Journal:	Oncoscience. 2015 Mar 14;2(3):285-93.
Title:	N of 1 case reports of exceptional responders accrued from pancreatic cancer patients enrolled in first-in-man studies from 2002 through 2012.
Author:	Garrido-Laguna, Ignacio\|Tometich, Danielle\|Hu, Nan\|Ying, Jian\|Geiersbach, Katherine\|Whisenant, Jonathan\|Wang, Kai\|Ross, Jeffrey S\|Sharma, Sunil
PMID:	25897431

109.
Journal:	Sci Rep. 2015 Jun 12;5:10867.
Title:	Caveolin-1 is Associated with Tumor Progression and Confers a Multi-Modality Resistance Phenotype in Pancreatic Cancer.
Author:	Chatterjee, Moumita\|Ben-Josef, Edgar\|Thomas, Dafydd G\|Morgan, Meredith A\|Zalupski, Mark M\|Khan, Gazala\|Andrew Robinson, Charles\|Griffith, Kent A\|Chen, Ching-Shih\|Ludwig, Thomas\|Bekaii-Saab, Tanios\|Chakravarti, Arnab\|Williams, Terence M
PMID:	26065715

110.
Journal:	Oncotarget. 2015 Sep 22;6(28):25308-19.
Title:	Calmodulin antagonists promote TRA-8 therapy of resistant pancreatic cancer.
Author:	Yuan, Kaiyu\|Yong, Sun\|Xu, Fei\|Zhou, Tong\|McDonald, Jay M\|Chen, Yabing
PMID:	26320171

111.
Journal:	Oncotarget. 2015 Nov 24;6(37):39521-37.
Title:	Novel agents for advanced pancreatic cancer.
Author:	Akinleye, Akintunde\|Iragavarapu, Chaitanya\|Furqan, Muhammad\|Cang, Shundong\|Liu, Delong
PMID:	26369833

112.
Journal:	Int J Clin Exp Med. 2015 Nov 15;8(11):20349-54. eCollection 2015.
Title:	Role of sphingosine 1-phosphate in human pancreatic cancer cells proliferation and migration.
Author:	Guo, Yun-Xia\|Ma, Ying-Jie\|Han, Li\|Wang, Yu-Jie\|Han, Ji-Ao\|Zhu, Ying
PMID:	26884951

113.
Journal:	Oncotarget. 2016 Feb 9;7(6):7253-67.
Title:	A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer.
Author:	Paladino, David\|Yue, Peibin\|Furuya, Hideki\|Acoba, Jared\|Rosser, Charles J\|Turkson, James
PMID:	26695438

114.
Journal:	Bioorg Med Chem Lett. 2016 Feb 15;26(4):1237-44.
Title:	Identification of initial leads directed at the calmodulin-binding region on the Src-SH2 domain that exhibit anti-proliferation activity against pancreatic cancer.
Author:	Tzou, Ywh-Min\|Bailey, Sarah K\|Yuan, Kaiyu\|Shin, Ronald\|Zhang, Wei\|Chen, Yabing\|Singh, Raj K\|Shevde, Lalita A\|Krishna, N Rama
PMID:	26803204

115.
Journal:	Mol Med Rep. 2016 Jun;13(6):4774-8.
Title:	Src/STAT3 signaling pathways are involved in KAI1-induced downregulation of VEGF-C expression in pancreatic cancer.
Author:	Liu, Xu\|Guo, Xiaozhong\|Li, Hongyu\|Chen, Jiang\|Qi, Xingshun
PMID:	27082851

116.
Journal:	PLoS One. 2016 May 13;11(5):e0155264.
Title:	Kaempferol Inhibits Pancreatic Cancer Cell Growth and Migration through the Blockade of EGFR-Related Pathway In Vitro.
Author:	Lee, Jungwhoi\|Kim, Jae Hoon
PMID:	27175782

117.
Journal:	Mol Cell Biol. 2016 Sep 26;36(20):2596-611.
Title:	Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells.
Author:	Li, Chunhui\|MacDonald, James I S\|Talebian, Asghar\|Leuenberger, Jennifer\|Seah, Claudia\|Pasternak, Stephen H\|Michnick, Stephen W\|Meakin, Susan O
PMID:	27503856

118.
Journal:	PLoS One. 2016 Oct 19;11(10):e0162821.
Title:	Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells.
Author:	Ma, Yong-Chao\|Wang, Zhi-Xin\|Jin, Shao-Ju\|Zhang, Yan-Xin\|Hu, Guo-Qiang\|Cui, Dong-Tao\|Wang, Jiang-Shuan\|Wang, Min\|Wang, Fu-Qing\|Zhao, Zhi-Jun
PMID:	27760157

119.
Journal:	Cancer Res. 2017 Jan 1;77(1):41-52.
Title:	Heterogeneous Stromal Signaling within the Tumor Microenvironment Controls the Metastasis of Pancreatic Cancer.
Author:	Rucki, Agnieszka A\|Foley, Kelly\|Zhang, Pingbo\|Xiao, Qian\|Kleponis, Jennifer\|Wu, Annie A\|Sharma, Rajni\|Mo, Guanglan\|Liu, Angen\|Van Eyk, Jennifer\|Jaffee, Elizabeth M\|Zheng, Lei
PMID:	27821486

120.
Journal:	Theranostics. 2017 Jan 11;7(3):594-613.
Title:	Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity.
Author:	Ahn, Hye-Mi\|Ryu, Jihye\|Song, Jin Myeong\|Lee, Yunhee\|Kim, Hye-Jin\|Ko, Dongjoon\|Choi, Inpyo\|Kim, Sang Jick\|Lee, Jung Weon\|Kim, Semi
PMID:	28255353

121.
Journal:	Biochem Pharmacol. 2017 Sep 15;140:1-7.
Title:	Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.
Author:	Rohira, Aarti D\|Lonard, David M
PMID:	28390937

122.
Journal:	Cell Rep. 2017 Jul 25;20(4):999-1015.
Title:	A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution.
Author:	Anderson, Grace R\|Winter, Peter S\|Lin, Kevin H\|Nussbaum, Daniel P\|Cakir, Merve\|Stein, Elizabeth M\|Soderquist, Ryan S\|Crawford, Lorin\|Leeds, Jim C\|Newcomb, Rachel\|Stepp, Priya\|Yip, Catherine\|Wardell, Suzanne E\|Tingley, Jennifer P\|Ali, Moiez\|Xu, Mengmeng\|Ry
PMID:	28746882

123.
Journal:	Invest New Drugs. 2018 Jun;36(3):442-450.
Title:	Dual Src and EGFR inhibition in combination with gemcitabine in advanced pancreatic cancer: phase I results : A phase I clinical trial.
Author:	Cardin, Dana B\|Goff, Laura W\|Chan, Emily\|Whisenant, Jennifer G\|Dan Ayers, G\|Takebe, Naoko\|Arlinghaus, Lori R\|Yankeelov, Thomas E\|Berlin, Jordan\|Merchant, Nipun
PMID:	28990119

124.
Journal:	Int J Mol Med. 2018 May;41(5):2813-2831.
Title:	Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification.
Author:	He, Rong-Quan\|Wu, Pei-Rong\|Xiang, Xue-Lian\|Yang, Xia\|Liang, Hai-Wei\|Qiu, Xiao-Hui\|Yang, Li-Hua\|Peng, Zhi-Gang\|Chen, Gang
PMID:	29484429

125.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2018 Aug 1;315(2):G302-G317.
Title:	P21-activated kinase 4 in pancreatic acinar cells is activated by numerous gastrointestinal hormones/neurotransmitters and growth factors by novel signaling, and its activation stimulates secretory/growth cascades.
Author:	Ramos-Alvarez, Irene\|Jensen, R T
PMID:	29672153

126.
Journal:	Cell Death Dis. 2018 May 1;9(5):538.
Title:	Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways.
Author:	Li, Yang\|Xi, Zhichao\|Chen, Xiaoqiong\|Cai, Shuangfan\|Liang, Chen\|Wang, Zhen\|Li, Yingyi\|Tan, Hongsheng\|Lao, Yuanzhi\|Xu, Hongxi
PMID:	29749405

127.
Journal:	Yonsei Med J. 2018 Aug;59(6):727-735.
Title:	Synergistic Anti-Cancer Effects of AKT and SRC Inhibition in Human Pancreatic Cancer Cells.
Author:	Ahn, Kang\|O, Young Moon\|Ji, Young Geon\|Cho, Han Jun\|Lee, Dong Hyeon
PMID:	29978609

128.
Journal:	Adv Biol Regul. 2018 Aug;69:16-34.
Title:	Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals.
Author:	Abrams, Stephen L\|Lertpiriyapong, Kvin\|Yang, Li V\|Martelli, Alberto M\|Cocco, Lucio\|Ratti, Stefano\|Falasca, Marco\|Murata, Ramiro M\|Rosalen, Pedro L\|Lombardi, Paolo\|Libra, Massimo\|Candido, Saverio\|Montalto, Giuseppe\|Cervello, Melchiorre\|Steelman, Linda S\|Mc
PMID:	29980405

129.
Journal:	Clin Exp Metastasis. 2018 Jul 9. pii: 10.1007/s10585-018-9919-5.
Title:	The therapeutic targeting of the FGFR1/Src/NF-kappaB signaling axis inhibits pancreatic ductal adenocarcinoma stemness and oncogenicity.
Author:	Lai, Shiue-Wei\|Bamodu, Oluwaseun Adebayo\|Tsai, Wen-Chiuan\|Chang, Yi-Ming\|Lee, Wei-Hwa\|Yeh, Chi-Tai\|Chao, Tsu-Yi
PMID:	29987671

130.
Journal:	Oncol Rep. 2018 Nov;40(5):3060-3068.
Title:	Allergenremoved Rhus verniciflua Stokes suppresses invasion and migration of pancreatic cancer cells through downregulation of the JAK/STAT and Src/FAK signaling pathways.
Author:	Kang, Youra\|Yoon, Seong Woo\|Park, Byoungduck
PMID:	30226611

131.
Journal:	Mol Oncol. 2018 Oct 20.
Title:	Gemcitabine exhibits a suppressive effect on pancreatic cancer cell growth by regulating processing of PVT1 to miR1207.
Author:	You, Lei\|Wang, Huanyu\|Yang, Gang\|Zhao, Fangyu\|Zhang, Jingcheng\|Liu, Ziwen\|Zhang, Taiping\|Liang, Zhiyong\|Liu, Changzheng\|Zhao, Yupei
PMID:	30341811