Primary Site >> Colorectal Cancer

Gene >> SRC

Journal: Prog Clin Biol Res. 1983;115:201-16.
Title: Cultured cells transformed by Rous sarcoma virus: a genetically defined model and its phenotype.
Author: Weber, M J|Nakamura, K D|Martinez, R
PMID: 6190185
Journal: Int J Cancer. 1984 Nov 15;34(5):725-30.
Title: Human tumor xenografts transplanted under the renal capsule of conventional mice. Growth rates and host immune response.
Author: Aamdal, S|Fodstad, O|Pihl, A
PMID: 6500747
Journal: J Biol Chem. 1986 Oct 15;261(29):13754-9.
Title: Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues.
Author: Rosen, N|Bolen, J B|Schwartz, A M|Cohen, P|DeSeau, V|Israel, M A
PMID: 3093483
Journal: Proc Natl Acad Sci U S A. 1987 Apr;84(8):2251-5.
Title: Activation of pp60c-src protein kinase activity in human colon carcinoma.
Author: Bolen, J B|Veillette, A|Schwartz, A M|DeSeau, V|Rosen, N
PMID: 2436227
Journal: J Cell Biochem. 1987 Oct;35(2):113-28.
Title: Analysis of pp60c-src tyrosine kinase activity and phosphotyrosyl phosphatase activity in human colon carcinoma and normal human colon mucosal cells.
Author: DeSeau, V|Rosen, N|Bolen, J B
PMID: 2448318
Journal: Oncogene Res. 1987 Jul;1(2):149-68.
Title: Analysis of pp60c-src in human colon carcinoma and normal human colon mucosal cells.
Author: Bolen, J B|Veillette, A|Schwartz, A M|Deseau, V|Rosen, N
PMID: 2453014
Journal: Anticancer Res. 1988 Sep-Oct;8(5A):1005-13.
Title: Phenotypic and genetic alterations in pre-cancerous cells in the colon.
Author: Lundy, J|Chen, J|Wang, P|Fromowitz, F|Schuss, A|Lynch, S|Brugge, J|Viola, M V
PMID: 3052255
Journal: Int J Cancer. 1988 Feb 15;41(2):287-96.
Title: Biological characterization and oncogene expression in human colorectal carcinoma cell lines.
Author: Trainer, D L|Kline, T|McCabe, F L|Faucette, L F|Feild, J|Chaikin, M|Anzano, M|Rieman, D|Hoffstein, S|Li, D J
PMID: 3338874
Journal: Oncogene Res. 1989;5(1):13-23.
Title: Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells.
Author: Foss, F M|Veillette, A|Sartor, O|Rosen, N|Bolen, J B
PMID: 2476706
Journal: J Clin Invest. 1989 Jun;83(6):2025-33.
Title: pp60c-src activation in human colon carcinoma.
Author: Cartwright, C A|Kamps, M P|Meisler, A I|Pipas, J M|Eckhart, W
PMID: 2498394
Journal: Proc Natl Acad Sci U S A. 1990 Jan;87(2):558-62.
Title: Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis.
Author: Cartwright, C A|Meisler, A I|Eckhart, W
PMID: 2105487
Journal: Am Rev Respir Dis. 1990 Dec;142(6 Pt 2):S54-6.
Title: src expression in small-cell lung carcinoma and other neuroendocrine malignancies.
Author: Pahlman, S|Hammerling, U
PMID: 2174663
Journal: Biochem Biophys Res Commun. 1990 Dec 31;173(3):894-901.
Title: Human cellular src gene product: identification of the myristoylated pp60c-src and blockage of its myristoyl acylation with N-fatty acyl compounds resulted in the suppression of colony formation.
Author: Shoji, S|Kurosawa, T|Inoue, H|Funakoshi, T|Kubota, Y
PMID: 2268350
Journal: Oncogene. 1991 Nov;6(11):1983-9.
Title: Effect of herbimycin A on growth and pp60c-src activity in human colon tumor cell lines.
Author: Garcia, R|Parikh, N U|Saya, H|Gallick, G E
PMID: 1719464
Journal: Oncogene. 1991 Feb;6(2):303-9.
Title: Preneoplastic lesions induced by myc and src oncogenes in a heterotopic rat colon.
Author: D'Emilia, J C|Mathey-Prevot, B|Jaros, K|Wolf, B|Steele, G Jr|Summerhayes, I C
PMID: 2000223
Journal: Anticancer Res. 1992 Sep-Oct;12(5):1721-4.
Title: Expression of the gene coding for the light chain of calpactin I (annexin II) in cell lines DiFi, HT-29, and WI-38.
Author: Wildrick, D M|Priebe-Malven, M|Boman, B M
PMID: 1280033
Journal: J Immunother (1991). 1992 Apr;11(3):159-68.
Title: Growth inhibition of human colorectal carcinoma cell lines by tumor necrosis factor-alpha correlates with reduced activity of pp60c-src.
Author: Novotny-Smith, C L|Gallick, G E
PMID: 1381217
Journal: Cancer. 1992 Sep 1;70(5 Suppl):1216-21.
Title: Molecular genetics of colorectal carcinoma.
Author: Hamilton, S R
PMID: 1511369
Journal: Cancer. 1992 Mar 15;69(6 Suppl):1589-91.
Title: Molecular genetic alterations as potential prognostic indicators in colorectal carcinoma.
Author: Hamilton, S R
PMID: 1540900
Journal: J Clin Invest. 1993 Jan;91(1):53-60.
Title: Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer.
Author: Talamonti, M S|Roh, M S|Curley, S A|Gallick, G E
PMID: 7678609
Journal: J Biol Chem. 1993 Apr 15;268(11):8181-7.
Title: Signal transduction through extracellular signal-regulated kinase-like pp57 blocked in differentiated colon carcinoma cells having low levels of c-src kinase.
Author: Lee, H|Hsu, S|Winawer, S|Friedman, E
PMID: 7681838
Journal: J Surg Res. 1993 Apr;54(4):293-8.
Title: Site-specific differences in pp60c-src activity in human colorectal metastases.
Author: Termuhlen, P M|Curley, S A|Talamonti, M S|Saboorian, M H|Gallick, G E
PMID: 7687314
Journal: Oncogene. 1993 Oct;8(10):2627-35.
Title: c-Yes tyrosine kinase activity in human colon carcinoma.
Author: Park, J|Meisler, A I|Cartwright, C A
PMID: 7690925
Journal: EXS. 1993;65:107-30.
Title: Signal transduction in c-met mediated motogenesis.
Author: Faletto, D L|Kaplan, D R|Halverson, D O|Rosen, E M|Vande Woude, G F
PMID: 8380734
Journal: J Clin Invest. 1994 Feb;93(2):509-15.
Title: Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis.
Author: Cartwright, C A|Coad, C A|Egbert, B M
PMID: 7509341
Journal: J Biol Chem. 1994 Dec 16;269(50):31711-9.
Title: Peptide inhibitors of src SH3-SH2-phosphoprotein interactions.
Author: Gilmer, T|Rodriguez, M|Jordan, S|Crosby, R|Alligood, K|Green, M|Kimery, M|Wagner, C|Kinder, D|Charifson, P
PMID: 7527393
Journal: Cancer Biochem Biophys. 1994 Oct;14(3):171-5.
Title: Activity of pp60c-src in 60 different cell lines derived from human tumors.
Author: Budde, R J|Ke, S|Levin, V A
PMID: 7537173
Journal: Oncol Rep. 1994 May;1(3):603-6.
Title: Immunohistochemically demonstrable pp60(c-SRC) in human breast-cancer.
Author: Partanen, S
PMID: 21607411
Journal: Oncogene. 1995 Nov 16;11(10):1955-62.
Title: Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association.
Author: Peng, Z Y|Cartwright, C A
PMID: 7478513
Journal: Oncogene. 1995 Oct 19;11(8):1649-55.
Title: Association of pp60c-src with biliary glycoprotein (CD66a), an adhesion molecule of the carcinoembryonic antigen family downregulated in colorectal carcinomas.
Author: Brummer, J|Neumaier, M|Gopfert, C|Wagener, C
PMID: 7478590
Journal: J Biol Chem. 1995 Feb 3;270(5):2298-304.
Title: Cell spreading in Colo 201 by staurosporin is alpha 3 beta 1 integrin-mediated with tyrosine phosphorylation of Src and tensin.
Author: Yoshimura, M|Nishikawa, A|Nishiura, T|Ihara, Y|Kanayama, Y|Matsuzawa, Y|Taniguchi, N
PMID: 7530722
Journal: Jpn J Clin Oncol. 1995 Feb;25(1):5-9.
Title: Expression of C-terminal src kinase in human colorectal cancer cell lines.
Author: Watanabe, N|Matsuda, S|Kuramochi, S|Tsuzuku, J|Yamamoto, T|Endo, K
PMID: 7533218
Journal: Mol Cell Biol. 1995 May;15(5):2374-82.
Title: Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells.
Author: Park, J|Cartwright, C A
PMID: 7739521
Journal: J Biol Chem. 1995 Jun 30;270(26):15591-7.
Title: Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha.
Author: Stover, D R|Becker, M|Liebetanz, J|Lydon, N B
PMID: 7797556
Journal: Eur J Surg Oncol. 1995 Feb;21(1):96-100.
Title: The genetic basis of colorectal cancer--clinical implications.
Author: Tsiotou, A G|Krespis, E N|Sakorafas, G H|Krespi, A E
PMID: 7851569
Journal: Inflamm Bowel Dis. 1995 Summer;1(2):142-58.
Title: Colon carcinogenesis in inflammatory bowel disease.
Author: Itzkowitz, S H|Greenwald, B|Meltzer, S J
PMID: 23282306
Journal: Dig Dis Sci. 1996 Apr;41(4):660-9.
Title: Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease.
Author: Alexander, R J|Panja, A|Kaplan-Liss, E|Mayer, L|Raicht, R F
PMID: 8674385
Journal: Br J Cancer. 1996 Aug;74(3):423-31.
Title: Syndecan-1 alterations during the tumorigenic progression of human colonic Caco-2 cells induced by human Ha-ras or polyoma middle T oncogenes.
Author: Levy, P|Munier, A|Baron-Delage, S|Di Gioia, Y|Gespach, C|Capeau, J|Cherqui, G
PMID: 8695359
Journal: Cancer Res. 1996 Oct 1;56(19):4516-21.
Title: Estradiol activation of human colon carcinoma-derived Caco-2 cell growth.
Author: Di Domenico, M|Castoria, G|Bilancio, A|Migliaccio, A|Auricchio, F
PMID: 8813150
Journal: Surg Oncol. 1996 Oct-Dec;5(5-6):201-10.
Title: The role of Src family kinases in the normal and neoplastic gastrointestinal tract.
Author: Banker, N|Evers, B M|Hellmich, M R|Townsend, C M Jr
PMID: 9129132
Journal: Clin Cancer Res. 1996 Aug;2(8):1397-404.
Title: Differential activation of pp60(c-src) and pp62(c-yes) in human colorectal carcinoma liver metastases.
Author: Han, N M|Curley, S A|Gallick, G E
PMID: 9816313
Journal: Int J Oncol. 1996 Aug;9(2):327-35.
Title: Genetics of colorectal cancer (Review).
Author: Peddanna, N|Mendis, R|Holt, S|Verma, R
PMID: 21541519
Journal: Int J Oncol. 1996 Sep;9(3):427-31.
Title: Effect of cytochrome P450 inducers on expression of oncogenes and a tumor suppressor gene in human colon cancer cells.
Author: Vasquez, H|Strobel, H
PMID: 21541530
Journal: Br J Cancer. 1997;75(2):241-50.
Title: Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion.
Author: Empereur, S|Djelloul, S|Di Gioia, Y|Bruyneel, E|Mareel, M|Van Hengel, J|Van Roy, F|Comoglio, P|Courtneidge, S|Paraskeva, C|Chastre, E|Gespach, C
PMID: 9010033
Journal: Cell Growth Differ. 1997 Mar;8(3):269-74.
Title: Decreased tumorigenicity of a human colon adenocarcinoma cell line by an antisense expression vector specific for c-Src.
Author: Staley, C A|Parikh, N U|Gallick, G E
PMID: 9056668
Journal: Oncogene. 1997 Apr 3;14(13):1589-600.
Title: Down-regulation of NF-kappaB activity and NF-kappaB p65 subunit expression by ras and polyoma middle T oncogenes in human colonic Caco-2 cells.
Author: Cadoret, A|Bertrand, F|Baron-Delage, S|Levy, P|Courtois, G|Gespach, C|Capeau, J|Cherqui, G
PMID: 9129150
Journal: Ann Surg Oncol. 1997 Apr-May;4(3):264-8.
Title: Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation.
Author: Han, N M|Fleming, R Y|Curley, S A|Gallick, G E
PMID: 9142389
Journal: Int J Cancer. 1997 May 16;71(4):645-53.
Title: Adhesion of HT-29 colon carcinoma cells to E-selectin results in increased tyrosine phosphorylation and decreased activity of c-src.
Author: Soltesz, S A|Powers, E A|Geng, J G|Fisher, C
PMID: 9178821
Journal: Bull Cancer. 1997 Mar;84(3):235-7.
Title: [Oncogenic activation of p21ras or pp60c-src in human colonic Caco-2 cells induces post-translation alterations of syndecan-1].
Author: Levy, P|Munier, A|Baron-Delage, S|Chastre, E|Gespach, C|Capeau, J|Cherqui, G
PMID: 9207867
Journal: Surgery. 1997 Aug;122(2):180-5; discussion 185-6.
Title: Src-mediated activation of the human neurotensin/neuromedin N promoter.
Author: Banker, N A|Hellmich, M R|Kim, H J|Townsend, C M Jr|Evers, B M
PMID: 9288121
Journal: Surgery. 1997 Aug;122(2):501-7.
Title: Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by activity of src kinase.
Author: Fleming, R Y|Ellis, L M|Parikh, N U|Liu, W|Staley, C A|Gallick, G E
PMID: 9288158
Journal: Cell Growth Differ. 1997 Dec;8(12):1287-95.
Title: Overexpression of normal c-Src in poorly metastatic human colon cancer cells enhances primary tumor growth but not metastatic potential.
Author: Irby, R|Mao, W|Coppola, D|Jove, R|Gamero, A|Cuthbertson, D|Fujita, D J|Yeatman, T J
PMID: 9419417
Journal: Oncogene. 1997 Dec 18;15(25):3083-90.
Title: Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential.
Author: Mao, W|Irby, R|Coppola, D|Fu, L|Wloch, M|Turner, J|Yu, H|Garcia, R|Jove, R|Yeatman, T J
PMID: 9444956
Journal: Oncol Rep. 1997 Mar-Apr;4(2):451-3.
Title: Changes in c-src activity in a human colon cancer cell line during differentiation.
Author: Sovova, V|Kucerova, D|Liskova, M|Sloncova, E|Tuhackova, Z
PMID: 21590078
Journal: J Biol Chem. 1998 Jan 9;273(2):1052-7.
Title: Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src.
Author: Ellis, L M|Staley, C A|Liu, W|Fleming, R Y|Parikh, N U|Bucana, C D|Gallick, G E
PMID: 9422768
Journal: Lab Invest. 1998 Mar;78(3):365-71.
Title: Elevated c-Src protein expression is an early event in colonic neoplasia.
Author: Iravani, S|Mao, W|Fu, L|Karl, R|Yeatman, T|Jove, R|Coppola, D
PMID: 9520949
Journal: Cancer Chemother Pharmacol. 1998;41(5):417-22.
Title: Geldanamycin-induced cytotoxicity in human colon-cancer cell lines: evidence against the involvement of c-Src or DT-diaphorase.
Author: Brunton, V G|Steele, G|Lewis, A D|Workman, P
PMID: 9523739
Journal: Int J Cancer. 1998 Mar 30;76(1):91-8.
Title: De novo expression of the alpha5beta1-fibronectin receptor in HT29 colon-cancer cells reduces activity of C-SRC. Increase of C-SRC activity by attachment on fibronectin.
Author: Schmidt, R|Streit, M|Kaiser, R|Herzberg, F|Schirner, M|Schramm, K|Kaufmann, C|Henneken, M|Schafer-Korting, M|Thiel, E|Kreuser, E D
PMID: 9533767
Journal: Dig Dis Sci. 1998 Jul;43(7):1454-64.
Title: Analysis of signaling protein kinases in human colon or colorectal carcinomas.
Author: Licato, L L|Brenner, D A
PMID: 9690379
Journal: Antisense Nucleic Acid Drug Dev. 1998 Oct;8(5):391-400.
Title: The human c-Src proto-oncogene promoter contains multiple targets for triplex-forming oligonucleotides.
Author: Ritchie, S|Bonham, K
PMID: 9826266
Journal: Nat Genet. 1999 Feb;21(2):187-90.
Title: Activating SRC mutation in a subset of advanced human colon cancers.
Author: Irby, R B|Mao, W|Coppola, D|Kang, J|Loubeau, J M|Trudeau, W|Karl, R|Fujita, D J|Jove, R|Yeatman, T J
PMID: 9988270
Journal: J Biol Chem. 1999 Jun 25;274(26):18428-37.
Title: Transcriptional induction of the urokinase receptor gene by a constitutively active Src. Requirement of an upstream motif (-152/-135) bound with Sp1.
Author: Allgayer, H|Wang, H|Gallick, G E|Crabtree, A|Mazar, A|Jones, T|Kraker, A J|Boyd, D D
PMID: 10373450
Journal: Acta Pharm Hung. 1999 Jun;69(3):115-22.
Title: [Preparation and characterization of potential antineoplastic agents].
Author: Orfi, L|Waczek, F|Szabo, M|Kovesdi, I|Meszaros, G|Idei, M|Horvath, A|Hollosy, F|Mak, M|Szegedi, Z|Szende, B|Keri, G|Noszal, B
PMID: 10401154
Journal: Cancer Res. 1999 Sep 1;59(17):4222-4.
Title: Absence of genetic alteration at codon 531 of the human c-src gene in 479 advanced colorectal cancers from Japanese and Caucasian patients.
Author: Daigo, Y|Furukawa, Y|Kawasoe, T|Ishiguro, H|Fujita, M|Sugai, S|Nakamori, S|Liefers, G J|Tollenaar, R A|van de Velde, C J|Nakamura, Y
PMID: 10485460
Journal: Curr Biol. 1999 Sep 23;9(18):1039-42.
Title: Ubiquitin-dependent degradation of active Src.
Author: Hakak, Y|Martin, G S
PMID: 10508617
Journal: Cancer Res. 1999 Dec 15;59(24):6145-52.
Title: Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest.
Author: Moasser, M M|Srethapakdi, M|Sachar, K S|Kraker, A J|Rosen, N
PMID: 10626805
Journal: Cancer Lett. 2000 Mar 31;150(2):201-4.
Title: No evidence of correlation between mutation at codon 531 of src and the risk of colon cancer in Chinese.
Author: Wang, N M|Yeh, K T|Tsai, C H|Chen, S J|Chang, J G
PMID: 10704743
Journal: Jpn J Cancer Res. 2000 Apr;91(4):395-8.
Title: Mutation of the SRC gene in endometrial carcinoma.
Author: Sugimura, M|Kobayashi, K|Sagae, S|Nishioka, Y|Ishioka, S|Terasawa, K|Tokino, T|Kudo, R
PMID: 10804287
Journal: Biochem Biophys Res Commun. 2000 Jul 5;273(2):425-30.
Title: Deregulation of the cytoplasmic tyrosine kinase cSrc in the absence of a truncating mutation at codon 531 in human bladder carcinoma.
Author: Benistant, C|Chapuis, H|Mottet, N|Noletti, J|Crapez, E|Bali, J P|Roche, S
PMID: 10873622
Journal: Biochem Biophys Res Commun. 2000 Jul 14;273(3):1116-20.
Title: Expression of N-myristoyltransferase inhibitor protein and its relationship to c-Src levels in human colon cancer cell lines.
Author: Rajala, R V|Dehm, S|Bi, X|Bonham, K|Sharma, R K
PMID: 10891381
Journal: Cancer Genet Cytogenet. 2000 Aug;121(1):94-5.
Title: Lack of activating c-SRC mutations at codon 531 in rectal cancer.
Author: Nilbert, M|Fernebro, E
PMID: 10958949
Journal: Biochem Pharmacol. 2000 Oct 1;60(7):885-98.
Title: Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors.
Author: Kraker, A J|Hartl, B G|Amar, A M|Barvian, M R|Showalter, H D|Moore, C W
PMID: 10974196
Journal: Int J Cancer. 2000 Nov 1;88(3):384-91.
Title: Overexpression of the csk gene suppresses tumor metastasis in vivo.
Author: Nakagawa, T|Tanaka, S|Suzuki, H|Takayanagi, H|Miyazaki, T|Nakamura, K|Tsuruo, T
PMID: 11054667
Journal: FASEB J. 2001 Feb;15(2):351-61.
Title: Induction of scattering and cellular invasion by trefoil peptides in src- and RhoA-transformed kidney and colonic epithelial cells.
Author: Emami, S|Le Floch , N|Bruyneel, E|Thim, L|May, F|Westley, B|Rio, M|Mareel, M|Gespach, C
PMID: 11156951
Journal: Br J Cancer. 2001 Jan;84(2):196-8.
Title: Lack of mutation at codon 531 of SRC in advanced colorectal cancers from Italian patients.
Author: Laghi, L|Bianchi, P|Orbetegli, O|Gennari, L|Roncalli, M|Malesci, A
PMID: 11161376
Journal: FEBS Lett. 2001 Jan 5;487(3):367-71.
Title: SRC transcriptional activation in a subset of human colon cancer cell lines.
Author: Dehm, S|Senger, M A|Bonham, K
PMID: 11163360
Journal: FASEB J. 2001 Jul;15(9):1517-28.
Title: Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase- and thromboxane A2 receptor-dependent signaling pathways.
Author: Rodrigues, S|Nguyen, Q D|Faivre, S|Bruyneel, E|Thim, L|Westley, B|May, F|Flatau, G|Mareel, M|Gespach, C|Emami, S
PMID: 11427483
Journal: Cancer. 2001 Jul 1;92(1):61-70.
Title: Reduced C-terminal Src kinase activity is correlated inversely with pp60(c-src) activity in colorectal carcinoma.
Author: Cam, W R|Masaki, T|Shiratori, Y|Kato, N|Ikenoue, T|Okamoto, M|Igarashi, K|Sano, T|Omata, M
PMID: 11443610
Journal: J Biol Chem. 2001 Oct 5;276(40):37273-9. Epub 2001 Aug 3.
Title: Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells.
Author: Rosen, K|Coll, M L|Li, A|Filmus, J
PMID: 11487584
Journal: Gastroenterology. 2002 Feb;122(2):331-9.
Title: Tumor necrosis factor alpha stimulates invasion of Src-activated intestinal cells.
Author: Kawai, Naoki|Tsuji, Shingo|Tsujii, Masahiko|Ito, Toshifumi|Yasumaru, Masakazu|Kakiuchi, Yoshimi|Kimura, Arata|Komori, Masato|Sasaki, Yutaka|Hayashi, Norio|Kawano, Sunao|Dubois, Raymond|Hori, Masatsugu
PMID: 11832448
Journal: Nat Med. 2002 Mar;8(3):289-93.
Title: Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy.
Author: Pai, Rama|Soreghan, Brian|Szabo, Imre L|Pavelka, Meredith|Baatar, Dolgor|Tarnawski, Andrzej S
PMID: 11875501
Journal: Cancer. 2002 Jan 15;94(2):344-51.
Title: Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis.
Author: Aligayer, Heike|Boyd, Douglas D|Heiss, Markus M|Abdalla, Eddie K|Curley, Steven A|Gallick, Gary E
PMID: 11900220
Journal: Cancer Res. 2002 May 1;62(9):2669-74.
Title: Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells.
Author: Irby, Rosalyn B|Yeatman, Timothy J
PMID: 11980666
Journal: Nat Cell Biol. 2002 Aug;4(8):632-8.
Title: Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.
Author: Avizienyte, Egle|Wyke, Anne W|Jones, Robert J|McLean, Gordon W|Westhoff, M Andrew|Brunton, Valerie G|Frame, Margaret C
PMID: 12134161
Journal: Oncogene. 2002 Sep 12;21(41):6340-7.
Title: The ubiquitous and tissue specific promoters of the human SRC gene are repressed by inhibitors of histone deacetylases.
Author: Kostyniuk, Calley L|Dehm, Scott M|Batten, Danielle|Bonham, Keith
PMID: 12214274
Journal: Oncogene. 2002 Oct 17;21(47):7256-65.
Title: Identification of Src transformation fingerprint in human colon cancer.
Author: Malek, Renae L|Irby, Rosalyn B|Guo, Qingbin M|Lee, Kerry|Wong, Sylvia|He, Mei|Tsai, Jennifer|Frank, Bryan|Liu, Edison T|Quackenbush, John|Jove, Richard|Yeatman, Timothy J|Lee, Norman H
PMID: 12370817
Journal: Br J Cancer. 2002 Nov 4;87(10):1128-35.
Title: Elevated c-Src is linked to altered cell-matrix adhesion rather than proliferation in KM12C human colorectal cancer cells.
Author: Jones, R J|Avizienyte, E|Wyke, A W|Owens, D W|Brunton, V G|Frame, M C
PMID: 12402152
Journal: J Exp Ther Oncol. 2002 Jul-Aug;2(4):237-45.
Title: Src protein kinase pp60c-src influences adhesion stabilization of HT-29 colon carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow.
Author: Haier, Jorg|Gallick, Garry E|Nicolson, Garth L
PMID: 12416028
Journal: Oncogene. 2002 Nov 7;21(51):7797-807.
Title: Src activation regulates anoikis in human colon tumor cell lines.
Author: Windham, T Christopher|Parikh, Nila U|Siwak, Doris R|Summy, Justin M|McConkey, David J|Kraker, Alan J|Gallick, Gary E
PMID: 12420216
Journal: Pharmacogenomics. 2002 Nov;3(6):763-80.
Title: Pharmacogenomic strategies for developing customized chemotherapy in non-small cell lung cancer.
Author: Sarries, Carme|Haura, Eric B|Roig, Barbara|Taron, Miquel|Abad, Albert|Scagliotti, Giorgio|Rosell, Rafael
PMID: 12437479
Journal: Nucleic Acids Res. 2003 Mar 1;31(5):1502-13.
Title: Identification of the SRC pyrimidine-binding protein (SPy) as hnRNP K: implications in the regulation of SRC1A transcription.
Author: Ritchie, Shawn A|Pasha, Mohammed K|Batten, Danielle J P|Sharma, Rajendra K|Olson, Douglas J H|Ross, Andrew R S|Bonham, Keith
PMID: 12595559
Journal: J Cell Sci. 2003 Apr 1;116(Pt 7):1187-97.
Title: Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells.
Author: Hollande, Frederic|Lee, Debra J|Choquet, Armelle|Roche, Serge|Baldwin, Graham S
PMID: 12615962
Journal: Cancer Res. 2003 May 1;63(9):2330-4.
Title: Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1.
Author: Fukuda, Ryo|Kelly, Brian|Semenza, Gregg L
PMID: 12727858
Journal: Mol Cancer Ther. 2003 May;2(5):461-9.
Title: Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tu
Author: Laird, A Douglas|Li, Guangmin|Moss, Katherine G|Blake, Robert A|Broome, Martin A|Cherrington, Julie M|Mendel, Dirk B
PMID: 12748308
Journal: Anticancer Res. 2003 Mar-Apr;23(2B):1517-24.
Title: Insulin-like growth factor 1 receptor activates c-SRC and modifies transformation and motility of colon cancer in vitro.
Author: Sekharam, Madhavi|Nasir, Aejaz|Kaiser, Hans E|Coppola, Domenico
PMID: 12820418
Journal: J Biol Chem. 2003 Sep 12;278(37):35451-7. Epub 2003 Jun 24.
Title: Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor.
Author: Buchanan, F Gregory|Wang, Dingzhi|Bargiacchi, Francesca|DuBois, Raymond N
PMID: 12824187
Journal: Cell Physiol Biochem. 2003;13(3):135-46.
Title: Absence of adhesion triggers differential FAK and SAPKp38 signals in SW620 human colon cancer cells that may inhibit adhesiveness and lead to cell death.
Author: Walsh, Mary F|Thamilselvan, Vijayalakshmi|Grotelueschen, Rainer|Farhana, Lulu|Basson, Marc
PMID: 12876384
Journal: Mol Cancer Res. 2003 Aug;1(10):755-64.
Title: Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.
Author: Golubovskaya, Vita M|Gross, Steven|Kaur, Aparna S|Wilson, Richard I|Xu, Li-Hui|Yang, Xi Hui|Cance, William G
PMID: 12939401
Journal: Gastroenterology. 2004 Jan;126(1):8-18.
Title: Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling.
Author: Thamilselvan, Vijayalakshmi|Basson, Marc D
PMID: 14699482
Journal: J Biol Chem. 2004 Apr 30;279(18):19335-49. Epub 2004 Feb 12.
Title: Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.
Author: Bedirian, Arda|Baldwin, Cindy|Abe, Jun-ichi|Takano, Tomoko|Lemay, Serge
PMID: 14963042
Journal: Clin Cancer Res. 2004 Feb 15;10(4):1545-55.
Title: Combination of an SRC kinase inhibitor with a novel pharmacological antagonist of the urokinase receptor diminishes in vitro colon cancer invasiveness.
Author: Boyd, Douglas D|Wang, Heng|Avila, Hector|Parikh, Nila U|Kessler, Horst|Magdolen, Victor|Gallick, Gary E
PMID: 14977859
Journal: J Biol Chem. 2004 May 14;279(20):20927-34. Epub 2004 Mar 9.
Title: Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
Author: Darmoul, Dalila|Gratio, Valerie|Devaud, Helene|Laburthe, Marc
PMID: 15010475
Journal: Biochem Cell Biol. 2004 Apr;82(2):263-74.
Title: SRC gene expression in human cancer: the role of transcriptional activation.
Author: Dehm, Scott M|Bonham, Keith
PMID: 15060621
Journal: Mol Biol Cell. 2004 Jun;15(6):2794-803. Epub 2004 Apr 9.
Title: Src SH3/2 domain-mediated peripheral accumulation of Src and phospho-myosin is linked to deregulation of E-cadherin and the epithelial-mesenchymal transition.
Author: Avizienyte, Egle|Fincham, Valerie J|Brunton, Valerie G|Frame, Margaret C
PMID: 15075377
Journal: Gene. 2004 Aug 4;337:141-50.
Title: Regulation of alternative SRC promoter usage in HepG2 hepatocellular carcinoma cells.
Author: Dehm, Scott M|Bonham, Keith
PMID: 15276210
Journal: Steroids. 2004 Aug;69(8-9):517-22.
Title: Rapid signalling pathway activation by androgens in epithelial and stromal cells.
Author: Castoria, Gabriella|Lombardi, Maria|Barone, Maria Vittoria|Bilancio, Antonio|Di Domenico, Marina|De Falco, Antonietta|Varricchio, Lilian|Bottero, Daniela|Nanayakkara, Merlin|Migliaccio, Antimo|Auricchio, Ferdinando
PMID: 15288763
Journal: J Biol Chem. 2004 Sep 24;279(39):40400-4.
Title: Agonist-independent activation of Src tyrosine kinase by a cholecystokinin-2 (CCK2) receptor splice variant.
Author: Olszewska-Pazdrak, Barbara|Townsend, Courtney M Jr|Hellmich, Mark R
PMID: 15292208
Journal: J Biol Chem. 2004 Oct 29;279(44):46113-21. Epub 2004 Aug 23.
Title: Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.
Author: Griffiths, Gareth J|Koh, Mei Yee|Brunton, Valerie G|Cawthorne, Christopher|Reeves, Natalie A|Greaves, Martin|Tilby, Michael J|Pearson, D Graham|Ottley, Christopher J|Workman, Paul|Frame, Margaret C|Dive, Caroline
PMID: 15326164
Journal: Biochem Biophys Res Commun. 2004 Sep 24;322(3):1012-7.
Title: Expression of methionine aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29.
Author: Selvakumar, Ponniah|Lakshmikuttyamma, Ashakumary|Lawman, Zoe|Bonham, Keith|Dimmock, Jonathan R|Sharma, Rajendra K
PMID: 15336565
Journal: Mol Cancer Res. 2004 Sep;2(9):514-22.
Title: Activation of proteinase-activated receptor 1 promotes human colon cancer cell proliferation through epidermal growth factor receptor transactivation.
Author: Darmoul, Dalila|Gratio, Valerie|Devaud, Helene|Peiretti, Franck|Laburthe, Marc
PMID: 15383630
Journal: Am J Surg. 2004 Nov;188(5):467-73.
Title: Extracellular pressure stimulates colon cancer cell adhesion in vitro and to surgical wounds by Src (sarcoma protein) activation.
Author: van der Voort van Zyp, Jochem|Thamilselvan, Vijayalakshmi|Walsh, Mary|Polin, Lisa|Basson, Marc D
PMID: 15546552
Journal: Cell Prolif. 2004 Dec;37(6):427-41.
Title: Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals.
Author: Walsh, M F|Woo, R K-Y|Gomez, R|Basson, M D
PMID: 15548175
Journal: Clin Cancer Res. 2004 Dec 1;10(23):8028-36.
Title: Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice.
Author: Yezhelyev, Maksim V|Koehl, Gudrun|Guba, Markus|Brabletz, Thomas|Jauch, Karl-Walter|Ryan, Anderson|Barge, Alan|Green, Tim|Fennell, Michael|Bruns, Christiane J
PMID: 15585638
Journal: J Cell Biochem. 2005 Apr 1;94(5):917-43.
Title: Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.
Author: Jurutka, Peter W|Thompson, Paul D|Whitfield, G Kerr|Eichhorst, Kristina R|Hall, Neal|Dominguez, Carlos Encinas|Hsieh, Jui-Cheng|Haussler, Carol A|Haussler, Mark R
PMID: 15578590
Journal: J Cell Biochem. 2005 Apr 15;94(6):1148-62.
Title: Construction and characterization of multiple human colon cancer cell lines for inducibly regulated gene expression.
Author: Welman, Arkadiusz|Cawthorne, Christopher|Barraclough, Jane|Smith, Nigel|Griffiths, Gareth J|Cowen, Rachel L|Williams, Judith C|Stratford, Ian J|Dive, Caroline
PMID: 15669025
Journal: Cancer Res. 2005 Feb 15;65(4):1335-42.
Title: Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior.
Author: Brunton, Valerie G|Avizienyte, Egle|Fincham, Valerie J|Serrels, Bryan|Metcalf, Chester A 3rd|Sawyer, Tomi K|Frame, Margaret C
PMID: 15735019
Journal: Cancer Res. 2005 Mar 1;65(5):1814-21.
Title: Iterative microarray and RNA interference-based interrogation of the SRC-induced invasive phenotype.
Author: Irby, Rosalyn B|Malek, Renae L|Bloom, Greg|Tsai, Jennifer|Letwin, Noah|Frank, Bryan C|Verratti, Kathleen|Yeatman, Timothy J|Lee, Norman H
PMID: 15753379
Journal: World J Gastroenterol. 2005 Apr 21;11(15):2351-3.
Title: c-src activating mutation analysis in Chinese patients with colorectal cancer.
Author: Tan, Ye-Xiong|Wang, Han-Tao|Zhang, Peng|Yan, Zhong-Hua|Dai, Guan-Long|Wu, Meng-Chao|Wang, Hong-Yang
PMID: 15818752
Journal: Carcinogenesis. 2005 Oct;26(10):1687-97. Epub 2005 May 25.
Title: The role of the cytoskeleton in differentially regulating pressure-mediated effects on malignant colonocyte focal adhesion signaling and cell adhesion.
Author: Thamilselvan, Vijayalakshmi|Basson, Marc D
PMID: 15917311
Journal: Cells Tissues Organs. 2005;179(1-2):73-80.
Title: The SRC-induced mesenchymal state in late-stage colon cancer cells.
Author: Avizienyte, Egle|Brunton, Valerie G|Fincham, Valerie J|Frame, Margaret C
PMID: 15942195
Journal: Cancer Res. 2005 Jun 15;65(12):5358-64.
Title: SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models.
Author: Golas, Jennifer M|Lucas, Judy|Etienne, Carlo|Golas, Jonathan|Discafani, Carolyn|Sridharan, Latha|Boghaert, Erwin|Arndt, Kim|Ye, Fei|Boschelli, Diane H|Li, Fangbiao|Titsch, Craig|Huselton, Christine|Chaudhary, Inder|Boschelli, Frank
PMID: 15958584
Journal: FEBS Lett. 2005 Jul 4;579(17):3497-502.
Title: Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation.
Author: Kunte, Dhananjay P|Wali, Ramesh K|Koetsier, Jennifer L|Hart, John|Kostjukova, Maria N|Kilimnik, Anna Y|Pyatkin, Ilia G|Strelnikova, Svetlana R|Roy, Hemant K
PMID: 15961079
Journal: Mol Carcinog. 2005 Aug;43(4):207-14.
Title: Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells.
Author: Lee, Jenq-Chang|Maa, Ming-Chei|Yu, Hsiu-Shan|Wang, Jung-Hui|Yen, Chia-Kuang|Wang, Shan-Tair|Chen, Yen-Jen|Liu, Yuan|Jin, Ying-Tai|Leu, Tzeng-Horng
PMID: 16001424
Journal: Cancer Res. 2005 Jul 15;65(14):6159-66.
Title: The novel gene EG-1 stimulates cellular proliferation.
Author: Lu, Ming|Zhang, Liping|Maul, Raymond Scott|Sartippour, Maryam R|Norris, Andrew|Whitelegge, Julian|Rao, Jian Yu|Brooks, Mai N
PMID: 16024617
Journal: J Cell Biochem. 2005 Sep 1;96(1):155-69.
Title: Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells.
Author: Liao, Chiung-Ho|Sang, Shengmin|Ho, Chi-Tang|Lin, Jen-Kun
PMID: 16052481
Journal: Int J Cancer. 2006 Feb 1;118(3):547-54.
Title: Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells.
Author: Hirsch, Calley L|Smith-Windsor, Erin L|Bonham, Keith
PMID: 16094635
Journal: Exp Cell Res. 2006 Feb 15;312(4):387-400.
Title: Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.
Author: Carothers, Adelaide M|Javid, Sara H|Moran, Amy E|Hunt, Daniel H|Redston, Mark|Bertagnolli, Monica M
PMID: 16368433
Journal: J Cell Sci. 2006 Jan 1;119(Pt 1):47-55.
Title: FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5.
Author: Li, Weiquan|Aurandt, Jennifer|Jurgensen, Claudia|Rao, Yi|Guan, Kun-Liang
PMID: 16371650
Journal: Biochim Biophys Acta. 2006 Apr;1765(2):148-54. Epub 2005 Dec 7.
Title: Methionine aminopeptidase 2 and cancer.
Author: Selvakumar, Ponniah|Lakshmikuttyamma, Ashakumary|Dimmock, Jonathan R|Sharma, Rajendra K
PMID: 16386852
Journal: Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1492-7. Epub 2006 Jan 23.
Title: Role of beta-arrestin 1 in the metastatic progression of colorectal cancer.
Author: Buchanan, F Gregory|Gorden, D Lee|Matta, Pranathi|Shi, Qiong|Matrisian, Lynn M|DuBois, Raymond N
PMID: 16432186
Journal: Cancer Res. 2006 Feb 15;66(4):2279-86.
Title: SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling.
Author: Coluccia, Addolorata Maria Luce|Benati, Daniela|Dekhil, Hafedh|De Filippo, Annamaria|Lan, Cathy|Gambacorti-Passerini, Carlo
PMID: 16489032
Journal: J Cell Biochem. 2006 Aug 15;98(6):1450-6.
Title: Functional role of VDR in the activation of p27Kip1 by the VDR/Sp1 complex.
Author: Cheng, Hsuen-Tsen|Chen, Jing-Yi|Huang, Yu-Chun|Chang, Hui-Chiu|Hung, Wen-Chun
PMID: 16518840
Journal: Biochimie. 2006 Sep;88(9):1209-16.
Title: Copper(II) and manganese(III) complexes of N'-[(2-hydroxy phenyl) carbonothioyl] pyridine-2-carbohydrazide: novel therapeutic agents for cancer.
Author: Shrivastav, Anuraag|Singh, Nand K|Tripathi, Pratibha|George, Theresa|Dimmock, Jonathan R|Sharma, Rajendra K
PMID: 16600465
Journal: World J Gastroenterol. 2006 Mar 28;12(12):1859-64.
Title: Glycine-extended gastrin activates two independent tyrosine-kinases in upstream of p85/p110 phosphatidylinositol 3-kinase in human colonic tumour cells.
Author: Ferrand, Audrey|Kowalski-Chauvel, Aline|Pannequin, Julie|Bertrand, Claudine|Fourmy, Daniel|Dufresne, Marlene|Seva, Catherine
PMID: 16609991
Journal: EMBO J. 2006 May 3;25(9):1895-905.
Title: Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression.
Author: Cursi, Silvia|Rufini, Alessandra|Stagni, Venturina|Condo, Ivano|Matafora, Vittoria|Bachi, Angela|Bonifazi, Antonio Paniccia|Coppola, Luigi|Superti-Furga, Giulio|Testi, Roberto|Barila, Daniela
PMID: 16619028
Journal: Br J Cancer. 2006 Jun 5;94(11):1710-7.
Title: Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases.
Author: Lesslie, D P|Summy, J M|Parikh, N U|Fan, F|Trevino, J G|Sawyer, T K|Metcalf, C A|Shakespeare, W C|Hicklin, D J|Ellis, L M|Gallick, G E
PMID: 16685275
Journal: Cancer Biol Ther. 2006 Sep;5(9):1169-78. Epub 2006 Sep 6.
Title: Extracellular pressure stimulates tumor cell adhesion in vitro by paxillin activation.
Author: van Zyp, J van der Voort|Conway, W C|Craig, D H|van Zyp, N van der Voort|Thamilselvan, V|Basson, M D
PMID: 16855384
Journal: Gan To Kagaku Ryoho. 2006 Jun;33 Suppl 1:4-18.
Title: [Timeline from discovery of 5-FU to development of an oral anticancer agent S-1 and its drug concept].
Author: Shirasaka, Tetsuhiko|Taguchi, Tetsuo
PMID: 16897967
Journal: Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1100-12. Epub 2006 Aug
Title: Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2.
Author: Khare, Sharad|Holgren, Cory|Samarel, Allen M
PMID: 16920701
Journal: J Cell Physiol. 2006 Dec;209(3):950-8.
Title: Alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells.
Author: Broom, Oliver Jay|Massoumi, Ramin|Sjolander, Anita
PMID: 16972245
Journal: Neoplasia. 2006 Nov;8(11):905-16.
Title: Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo.
Author: Welman, Arkadiusz|Cawthorne, Christopher|Ponce-Perez, Lourdes|Barraclough, Jane|Danson, Sarah|Murray, Stephen|Cummings, Jeff|Allen, Terry D|Dive, Caroline
PMID: 17132222
Journal: Mol Cancer Ther. 2006 Dec;5(12):3014-22. Epub 2006 Dec 5.
Title: Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib.
Author: Serrels, Alan|Macpherson, Iain R J|Evans, T R Jeffry|Lee, Francis Y|Clark, Edwin A|Sansom, Owen J|Ashton, Gabrielle H|Frame, Margaret C|Brunton, Valerie G
PMID: 17148760
Journal: Oncogene. 2007 May 3;26(20):2914-24. Epub 2006 Oct 30.
Title: RACK1 inhibits colonic cell growth by regulating Src activity at cell cycle checkpoints.
Author: Mamidipudi, V|Dhillon, N K|Parman, T|Miller, L D|Lee, K C|Cartwright, C A
PMID: 17072338
Journal: J Biol Chem. 2007 Feb 23;282(8):5413-9. Epub 2006 Dec 27.
Title: PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation.
Author: Liang, Fubo|Liang, Jiao|Wang, Wei-Qing|Sun, Jin-Peng|Udho, Eshwar|Zhang, Zhong-Yin
PMID: 17192274
Journal: FASEB J. 2007 Jun;21(8):1730-41. Epub 2007 Feb 22.
Title: FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway.
Author: Thamilselvan, Vijayalakshmi|Craig, David H|Basson, Marc D
PMID: 17317726
Journal: Clin Cancer Res. 2007 Feb 15;13(4):1123-32.
Title: Analysis of specific transcriptional regulators as early predictors of independent prognostic relevance in resected colorectal cancer.
Author: Maurer, Gabriele D|Leupold, Joerg H|Schewe, Denis M|Biller, Tobias|Kates, Ronald E|Hornung, Hans-Martin|Lau-Werner, Ulla|Post, Stefan|Allgayer, Heike
PMID: 17317820
Journal: Cell Signal. 2007 Aug;19(8):1722-32. Epub 2007 Mar 28.
Title: Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells.
Author: Grijelmo, Clara|Rodrigue, Christelle|Svrcek, Magalie|Bruyneel, Erik|Hendrix, An|de Wever, Olivier|Gespach, Christian
PMID: 17478078
Journal: J Biol Chem. 2007 Jul 6;282(27):19399-409. Epub 2007 May 12.
Title: Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase.
Author: Maa, Ming-Chei|Lee, Jenq-Chang|Chen, Yen-Jen|Chen, Yun-Ju|Lee, Yuch-Ching|Wang, Shan-Tair|Huang, Ching-Chung|Chow, Nan-Haw|Leu, Tzeng-Horng
PMID: 17496330
Journal: Mol Cancer Res. 2007 May;5(5):485-96.
Title: Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer.
Author: Leupold, Jorg H|Asangani, Irfan|Maurer, Gabriele D|Lengyel, Ernst|Post, Stefan|Allgayer, Heike
PMID: 17510314
Journal: J Exp Ther Oncol. 2007;6(3):205-17.
Title: Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells.
Author: Herynk, Matthew H|Zhang, Jing|Parikh, Nila U|Gallick, Gary E
PMID: 17552361
Journal: Genomics Proteomics Bioinformatics. 2007 Feb;5(1):15-24.
Title: Analysis of pathway activity in primary tumors and NCI60 cell lines using gene expression profiling data.
Author: Feng, Xing-Dong|Huang, Shu-Guang|Shou, Jian-Yong|Liao, Bi-Rong|Yingling, Jonathan M|Ye, Xiang|Lin, Xi|Gelbert, Lawrence M|Su, Eric W|Onyia, Jude E|Li, Shu-Yu
PMID: 17572360
Journal: Exp Cell Res. 2007 Sep 10;313(15):3175-88. Epub 2007 May 24.
Title: An active Src kinase-beta-actin association is linked to actin dynamics at the periphery of colon cancer cells.
Author: Avizienyte, Egle|Keppler, Melanie|Sandilands, Emma|Brunton, Valerie G|Winder, Steve J|Ng, Tony|Frame, Margaret C
PMID: 17651734
Journal: Cancer Res. 2007 Aug 1;67(15):7368-77.
Title: Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death.
Author: Lluis, Josep M|Buricchi, Francesca|Chiarugi, Paola|Morales, Albert|Fernandez-Checa, Jose C
PMID: 17671207
Journal: Pharmacol Res. 2007 Sep;56(3):248-53.
Title: Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro.
Author: Rossi, Lorena|Bonmassar, Enzo|Faraoni, Isabella
PMID: 17702597
Journal: Cancer Res. 2007 Sep 1;67(17):8240-7.
Title: Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab.
Author: Lu, Yang|Li, Xinqun|Liang, Ke|Luwor, Rodney|Siddik, Zahid H|Mills, Gordon B|Mendelsohn, John|Fan, Zhen
PMID: 17804738
Journal: Zhonghua Yi Xue Za Zhi. 2007 Jun 26;87(24):1704-8.
Title: [Molecular mechanism of gastrin increasing colon cancer cells' invasion].
Author: Cao, Jun|Yu, Jie-ping|Zhou, Lan|Song, Wen-chong|Luo, He-sheng|Yu, Hong-gang
PMID: 17825155
Journal: Am J Physiol Cell Physiol. 2007 Dec;293(6):C1862-74. Epub 2007 Sep 26.
Title: Alpha-actinin-1 phosphorylation modulates pressure-induced colon cancer cell adhesion through regulation of focal adhesion kinase-Src interaction.
Author: Craig, David H|Haimovich, Beatrice|Basson, Marc D
PMID: 17898132
Journal: Neoplasia. 2007 Sep;9(9):745-54.
Title: Increases in c-Yes expression level and activity promote motility but not proliferation of human colorectal carcinoma cells.
Author: Barraclough, Jane|Hodgkinson, Cassandra|Hogg, Alison|Dive, Caroline|Welman, Arkadiusz
PMID: 17898870
Journal: Cancer Res. 2007 Nov 1;67(21):10129-37.
Title: PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation.
Author: Zhu, Shudong|Bjorge, Jeffrey D|Fujita, Donald J
PMID: 17974954
Journal: Int J Oncol. 2007 Dec;31(6):1501-8.
Title: Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion.
Author: Van Slambrouck, Severine|Grijelmo, Clara|De Wever, Olivier|Bruyneel, Erik|Emami, Shahin|Gespach, Christian|Steelant, Wim F A
PMID: 17982677
Journal: J Enzyme Inhib Med Chem. 2007 Oct;22(5):638-46.
Title: Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells.
Author: Atatreh, Noor|Barraclough, Jane|Welman, Arkadiusz|Cawthorne, Christopher|Bryce, Richard A|Dive, Caroline|Freeman, Sally
PMID: 18035832
Journal: Anticancer Agents Med Chem. 2007 Nov;7(6):651-9.
Title: SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy.
Author: Johnson, Faye M|Gallick, Gary E
PMID: 18045060
Journal: Gastrointest Cancer Res. 2007;1(4 Suppl 2):S37-41.
Title: Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic.
Author: Kopetz, Scott
PMID: 19360146
Journal: Oncogene. 2008 Mar 27;27(14):2027-34. Epub 2007 Oct 15.
Title: Decreased CHK protein levels are associated with Src activation in colon cancer cells.
Author: Zhu, S|Bjorge, J D|Cheng, H C|Fujita, D J
PMID: 17934522
Journal: J Biol Chem. 2008 Feb 22;283(8):5023-33. Epub 2007 Dec 17.
Title: Suppression of v-Src transformation by andrographolide via degradation of the v-Src protein and attenuation of the Erk signaling pathway.
Author: Liang, Fong-Pin|Lin, Chao-Hsiung|Kuo, Cheng-Deng|Chao, Hsueh-Ping|Fu, Shu-Ling
PMID: 18086662
Journal: Int J Cancer. 2008 May 1;122(9):1999-2007.
Title: Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi.
Author: Zheng, Xinmin|Resnick, Ross J|Shalloway, David
PMID: 18183590
Journal: Cancer Res. 2008 Feb 1;68(3):815-25.
Title: The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition.
Author: Vigneron, Arnaud|Gamelin, Erick|Coqueret, Olivier
PMID: 18245483
Journal: Neurosignals. 2008;16(2-3):235-45.
Title: Tyrosine phosphorylation of netrin receptors in netrin-1 signaling.
Author: Ren, Xiu-Rong|Hong, Yan|Feng, Zhu|Yang, Hong-Mei|Mei, Lin|Xiong, Wen-Cheng
PMID: 18253061
Journal: Int J Cancer. 2008 Jun 15;122(12):2665-73.
Title: Src kinase induces tumor formation in the c-SRC C57BL/6 mouse.
Author: Kline, Christina Leah B|Jackson, Rosalind|Engelman, Robert|Pledger, Warren Jack|Yeatman, Timothy J|Irby, Rosalyn B
PMID: 18351644
Journal: Cancer Res. 2008 Apr 1;68(7):2250-8.
Title: Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer.
Author: Gautschi, Oliver|Tepper, Clifford G|Purnell, Phillip R|Izumiya, Yoshihiro|Evans, Christopher P|Green, Tim P|Desprez, Pierre Y|Lara, Primo N|Gandara, David R|Mack, Philip C|Kung, Hsing-Jien
PMID: 18381431
Journal: Curr Med Chem. 2008;15(10):978-90.
Title: ANTI-ADHESION evolves to a promising therapeutic concept in oncology.
Author: Schmidmaier, R|Baumann, P
PMID: 18393855
Journal: Clin Cancer Res. 2008 Apr 15;14(8):2253-62.
Title: Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model.
Author: Dougherty, Urszula|Sehdev, Amikar|Cerda, Sonia|Mustafi, Reba|Little, Nathaniel|Yuan, Weihua|Jagadeeswaran, Sujatha|Chumsangsri, Anusara|Delgado, Jorge|Tretiakova, Maria|Joseph, Loren|Hart, John|Cohen, Ezra E W|Aluri, Lata|Fichera, Alessandro|Bissonnette,
PMID: 18413814
Journal: Mol Biol Cell. 2008 Jul;19(7):2984-94.
Title: The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.
Author: Gianni, Davide|Bohl, Ben|Courtneidge, Sara A|Bokoch, Gary M
PMID: 18463161
Journal: Nat Clin Pract Gastroenterol Hepatol. 2008 Jun;5(6):306-7.
Title: Is Src the key to understanding metastasis and developing new treatments for colon cancer?
Author: Chen, Jiezhong
PMID: 18477987
Journal: J Biol Chem. 2008 Aug 15;283(33):22709-22.
Title: Potential molecular mechanism for c-Src kinase-mediated regulation of intestinal cell migration.
Author: Mathew, Sijo|George, Sudeep P|Wang, Yaohong|Siddiqui, Mohammad Rizwan|Srinivasan, Kamalakkannan|Tan, Langzhu|Khurana, Seema
PMID: 18482983
Journal: Bioorg Med Chem. 2008 Jun 1;16(11):5890-8.
Title: Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase.
Author: Cao, Xin|You, Qi-Dong|Li, Zhi-Yu|Guo, Qing-Long|Shang, Jing|Yan, Ming|Chern, Ji-Wang|Chen, Men-Ling
PMID: 18485715
Journal: Cancer Biomark. 2008;4(2):83-91.
Title: Identification of a functional EGF-R/p60c-src/STAT3 pathway in colorectal carcinoma: analysis of its long-term prognostic value.
Author: Hbibi, A Tadlaoui|Lagorce, C|Wind, P|Spano, J P|Des Guetz, G|Milano, G|Benamouzig, R|Rixe, O|Morere, J-F|Breau, J-L|Martin, A|Fagard, R
PMID: 18503159
Journal: Anticancer Res. 2008 Mar-Apr;28(2A):895-906.
Title: Rosiglitazone induces caveolin-1 by PPARgamma-dependent and PPRE-independent mechanisms: the role of EGF receptor signaling and its effect on cancer cell drug resistance.
Author: Tencer, Lilach|Burgermeister, Elke|Ebert, Matthias P|Liscovitch, Mordechai
PMID: 18507034
Journal: Eur J Surg Oncol. 2008 Nov;34(11):1253-61.
Title: Combined expression of the non-receptor protein tyrosine kinases FAK and Src in primary colorectal cancer is associated with tumor recurrence and metastasis formation.
Author: de Heer, P|Koudijs, M M|van de Velde, C J H|Aalbers, R I J M|Tollenaar, R A E M|Putter, H|Morreau, J|van de Water, B|Kuppen, P J K
PMID: 18556171
Journal: Eur J Cell Biol. 2008 Sep;87(8-9):569-79.
Title: Focal adhesion kinase is not required for Src-induced formation of invadopodia in KM12C colon cancer cells and can interfere with their assembly.
Author: Vitale, Sebastien|Avizienyte, Egle|Brunton, Valerie G|Frame, Margaret C
PMID: 18562041
Journal: Mol Cancer Ther. 2008 Jun;7(6):1376-85.
Title: Eps8 decreases chemosensitivity and affects survival of cervical cancer patients.
Author: Chen, Yun-Ju|Shen, Meng-Ru|Chen, Yen-Jen|Maa, Ming-Chei|Leu, Tzeng-Horng
PMID: 18566210
Journal: Mol Cancer Ther. 2008 Jul;7(7):1797-806.
Title: Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.
Author: Kunte, Dhananjay P|Wali, Ramesh K|Koetsier, Jennifer L|Roy, Hemant K
PMID: 18644992
Journal: J Clin Invest. 2008 Sep;118(9):3170-80.
Title: Colchicine inhibits pressure-induced tumor cell implantation within surgical wounds and enhances tumor-free survival in mice.
Author: Craig, David H|Owen, Cheri R|Conway, William C|Walsh, Mary F|Downey, Christina|Basson, Marc D
PMID: 18704196
Journal: Mol Cancer Ther. 2008 Sep;7(9):3064-70.
Title: Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells.
Author: Fan, Fan|Gray, Michael J|Dallas, Nikolaos A|Yang, Anthony D|Van Buren, George 2nd|Camp, E Ramsay|Ellis, Lee M
PMID: 18790786
Journal: Cancer Res. 2008 Oct 15;68(20):8210-20.
Title: Phosphorylated caveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration and invasion.
Author: Joshi, Bharat|Strugnell, Scott S|Goetz, Jacky G|Kojic, Liliana D|Cox, Michael E|Griffith, Obi L|Chan, Simon K|Jones, Steven J|Leung, Sher-Ping|Masoudi, Hamid|Leung, Samuel|Wiseman, Sam M|Nabi, Ivan R
PMID: 18922892
Journal: Cancer Res. 2008 Oct 15;68(20):8312-21.
Title: Src and ADAM-17-mediated shedding of transforming growth factor-alpha is a mechanism of acute resistance to TRAIL.
Author: Van Schaeybroeck, Sandra|Kelly, Donal M|Kyula, Joan|Stokesberry, Susan|Fennell, Dean A|Johnston, Patrick G|Longley, Daniel B
PMID: 18922903
Journal: Chem Biol. 2008 Oct 20;15(10):1029-34.
Title: Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor.
Author: Eelen, Guy|Valle, Noelia|Sato, Yoshiteru|Rochel, Natacha|Verlinden, Lieve|De Clercq, Pierre|Moras, Dino|Bouillon, Roger|Munoz, Alberto|Verstuyf, Annemieke
PMID: 18940664
Journal: Mol Carcinog. 2009 Feb;48(2):156-66.
Title: Src transformation of colonic epithelial cells: enhanced anchorage-independent growth in an Apc(+/min) background.
Author: Constancio-Lund, Sabata S|Brabek, Jan|Hanks, Steven K
PMID: 18613032
Journal: Clin Exp Metastasis. 2009;26(2):77-87.
Title: Src activity alters alpha3 integrin expression in colon tumor cells.
Author: Kline, Christina Leah B|Olson, Thomas L|Irby, Rosalyn B
PMID: 18839319
Journal: Int J Cancer. 2009 Apr 1;124(7):1517-25.
Title: Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase.
Author: Gratio, Valerie|Walker, Francine|Lehy, Therese|Laburthe, Marc|Darmoul, Dalila
PMID: 19058300
Journal: Int J Cancer. 2009 Apr 15;124(8):1990-6.
Title: Valproic acid enhances bosutinib cytotoxicity in colon cancer cells.
Author: Mologni, Luca|Cleris, Loredana|Magistroni, Vera|Piazza, Rocco|Boschelli, Frank|Formelli, Franca|Gambacorti-Passerini, Carlo
PMID: 19123474
Journal: BMC Cancer. 2009 Jan 12;9:12.
Title: Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.
Author: Sachdev, Sanjay|Bu, Yahao|Gelman, Irwin H
PMID: 19138410
Journal: DNA Repair (Amst). 2009 Mar 1;8(3):390-9.
Title: HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
Author: Ferrandiz, Nuria|Martin-Perez, Jorge|Blanco, Rosa|Donertas, Derya|Weber, Axel|Eilers, Martin|Dotto, Paolo|Delgado, M Dolores|Leon, Javier
PMID: 19150257
Journal: Cancer Res. 2009 Mar 15;69(6):2279-86.
Title: Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells.
Author: Leroy, Cedric|Fialin, Camille|Sirvent, Audrey|Simon, Valerie|Urbach, Serge|Poncet, Joel|Robert, Bruno|Jouin, Patrick|Roche, Serge
PMID: 19276381
Journal: Biochemistry. 2009 Jun 9;48(22):4780-8.
Title: Bimolecular fluorescence complementation demonstrates that the c-Fes protein-tyrosine kinase forms constitutive oligomers in living cells.
Author: Shaffer, Jonathan M|Hellwig, Sabine|Smithgall, Thomas E
PMID: 19382747
Journal: Cancer Res. 2009 May 1;69(9):3842-9.
Title: Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress.
Author: Kopetz, Scott|Lesslie, Donald P|Dallas, Nikolas A|Park, Serk I|Johnson, Marjorie|Parikh, Nila U|Kim, Michael P|Abbruzzese, James L|Ellis, Lee M|Chandra, Joya|Gallick, Gary E
PMID: 19383922
Journal: Yao Xue Xue Bao. 2009 Mar;44(3):288-95.
Title: [The design, synthesis and anticancer activity of 4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS].
Author: Cao, Xin|You, Qi-dong|Li, Zhi-yu|Guo, Qing-long|Yang, Yong|Shang, Jing|Yan, Ming|Chen, Ji-wang|Chen, Meng-ling
PMID: 19449526
Journal: Cancer Biol Ther. 2009 Jul;8(14):1313-7. Epub 2009 Jul 11.
Title: The signal pathways in azoxymethane-induced colon cancer and preventive implications.
Author: Chen, Jiezhong|Huang, Xu-Feng
PMID: 19502780
Journal: J Oncol. 2009;2009:896407.
Title: Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors.
Author: Egloff, Ann Marie|Grandis, Jennifer Rubin
PMID: 19636423
Journal: Mol Cell Proteomics. 2009 Oct;8(10):2382-95.
Title: Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays.
Author: Babel, Ingrid|Barderas, Rodrigo|Diaz-Uriarte, Ramon|Martinez-Torrecuadrada, Jorge Luis|Sanchez-Carbayo, Marta|Casal, J Ignacio
PMID: 19638618
Journal: Mol Cancer. 2009 Aug 24;8:65.
Title: NC2213: a novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells.
Author: Selvakumar, Ponniah|Lakshmikuttyamma, Ashakumary|Das, Umashankar|Pati, Hari N|Dimmock, Jonathan R|Sharma, Rajendra K
PMID: 19703310
Journal: Oncogene. 2009 Dec 17;28(50):4421-33.
Title: A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways.
Author: Mamidipudi, V|Cartwright, C A
PMID: 19767770
Journal: Transl Oncol. 2009 Dec;2(4):281-90.
Title: Focal adhesion kinase functions as an akt downstream target in migration of colorectal cancer cells.
Author: Tureckova, Jolana|Vojtechova, Martina|Krausova, Michaela|Sloncova, Eva|Korinek, Vladimir
PMID: 19956390
Journal: Carcinogenesis. 2010 Apr;31(4):597-606.
Title: TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways.
Author: Kim, Semi|Kang, Hee Young|Nam, Eun-Hee|Choi, Myung-Sook|Zhao, Xue-Feng|Hong, Chang Soo|Lee, Jung Weon|Lee, Jae Hyuk|Park, Young-Kyu
PMID: 20118200
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Apr;298(4):G551-62.
Title: Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.
Author: Singh, Pomila|Sarkar, Shubhashish|Umar, Shahid|Rengifo-Cam, William|Singh, Amar P|Wood, Thomas G
PMID: 20133951
Journal: Thromb Res. 2010 Jun;125(6):e323-8.
Title: Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation.
Author: Borensztajn, Keren|Peppelenbosch, Maikel P|Spek, C Arnold
PMID: 20347121
Journal: Int J Clin Exp Med. 2010 Feb 22;3(1):69-83.
Title: Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines.
Author: Pastor, Danielle M|Poritz, Lisa S|Olson, Thomas L|Kline, Christina L|Harris, Leonard R|Koltun, Walter A|Chinchilli, Vernon M|Irby, Rosalyn B
PMID: 20369042
Journal: Clin Colorectal Cancer. 2010 Apr;9(2):89-94.
Title: The SRC family of protein tyrosine kinases: a new and promising target for colorectal cancer therapy.
Author: Lieu, Christopher|Kopetz, Scott
PMID: 20378502
Journal: Mol Cell Biol. 2010 Jul;30(13):3262-74.
Title: Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.
Author: Tsygankova, Oxana M|Ma, Changqing|Tang, Waixing|Korch, Christopher|Feldman, Michael D|Lv, Yu|Brose, Marcia S|Meinkoth, Judy L
PMID: 20439492
Journal: Oncogene. 2010 Jun 24;29(25):3677-90.
Title: p140Cap dual regulation of E-cadherin/EGFR cross-talk and Ras signalling in tumour cell scatter and proliferation.
Author: Damiano, L|Di Stefano, P|Camacho Leal, M P|Barba, M|Mainiero, F|Cabodi, S|Tordella, L|Sapino, A|Castellano, I|Canel, M|Frame, M|Turco, E|Defilippi, P
PMID: 20453886
Journal: Mol Biol Cell. 2010 Jul 1;21(13):2338-54.
Title: A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.
Author: Ghosh, Pradipta|Beas, Anthony O|Bornheimer, Scott J|Garcia-Marcos, Mikel|Forry, Erin P|Johannson, Carola|Ear, Jason|Jung, Barbara H|Cabrera, Betty|Carethers, John M|Farquhar, Marilyn G
PMID: 20462955
Journal: PLoS One. 2010 Jun 4;5(6):e10966.
Title: Hypoxia activates the K-ras proto-oncogene to stimulate angiogenesis and inhibit apoptosis in colon cancer cells.
Author: Zeng, Min|Kikuchi, Hirotoshi|Pino, Maria S|Chung, Daniel C
PMID: 20532039
Journal: Genes Cells. 2010 Jun;15(7):711-724.
Title: Extracellular domain dependence of PTPalpha transforming activity.
Author: Tremper-Wells, Barbara|Resnick, Ross J|Zheng, Xinmin|Holsinger, Leslie J|Shalloway, David
PMID: 20545765
Journal: Clin Cancer Res. 2010 Aug 15;16(16):4165-77.
Title: Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.
Author: Arcaroli, John J|Touban, Basel M|Tan, Aik Choon|Varella-Garcia, Marileila|Powell, Rebecca W|Eckhardt, S Gail|Elvin, Paul|Gao, Dexiang|Messersmith, Wells A
PMID: 20682712
Journal: Curr Cancer Drug Targets. 2010 Dec;10(8):824-33.
Title: Strategies for overcoming inherent and acquired resistance to EGFR inhibitors by targeting downstream effectors in the RAS/PI3K pathway.
Author: Weickhardt, Andrew J|Tebbutt, Niall C|Mariadason, John M
PMID: 20718704
Journal: Genes Cells. 2010 Oct;15(10):1051-62.
Title: Purvalanol A, a CDK inhibitor, effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src.
Author: Hikita, Tomoya|Oneyama, Chitose|Okada, Masato
PMID: 20825494
Journal: Mol Biol Cell. 2010 Dec;21(23):4287-98.
Title: c-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells.
Author: Gianni, Davide|Taulet, Nicolas|DerMardirossian, Celine|Bokoch, Gary M
PMID: 20943948
Journal: J Cell Biochem. 2010 Dec 1;111(5):1082-6.
Title: Activation of signal pathways and the resistance to anti-EGFR treatment in colorectal cancer.
Author: Chen, Jiezhong|Huang, Xu-Feng|Katsifis, Andrew
PMID: 21053280
Journal: PLoS One. 2010 Nov 30;5(11):e14143.
Title: Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers.
Author: Kruewel, Thomas|Schenone, Silvia|Radi, Marco|Maga, Giovanni|Rohrbeck, Astrid|Botta, Maurizio|Borlak, Juergen
PMID: 21152443
Journal: Int J Cancer. 2011 Feb 15;128(4):951-61.
Title: Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.
Author: Nautiyal, Jyoti|Banerjee, Sanjeev|Kanwar, Shailender S|Yu, Yingjie|Patel, Bhaumik B|Sarkar, Fazlul H|Majumdar, Adhip P N
PMID: 20473900
Journal: Curr Drug Targets. 2011 Apr;12(4):563-78.
Title: Dasatinib: an anti-tumour agent via Src inhibition.
Author: Gnoni, Antonio|Marech, Ilaria|Silvestris, Nicola|Vacca, Angelo|Lorusso, Vito
PMID: 21226671
Journal: J Natl Cancer Inst. 2011 Mar 2;103(5):407-24.
Title: The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer.
Author: Baker, Ann-Marie|Cox, Thomas R|Bird, Demelza|Lang, Georgina|Murray, Graeme I|Sun, Xiao-Feng|Southall, Stacey M|Wilson, Jon R|Erler, Janine T
PMID: 21282564
Journal: Am J Physiol Cell Physiol. 2011 May;300(5):C1155-63.
Title: Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells.
Author: Chen, Min|Sastry, Sarita K|O'Connor, Kathleen L
PMID: 21289293
Journal: PLoS One. 2011 Feb 24;6(2):e17237.
Title: Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.
Author: Sancier, Florence|Dumont, Aurelie|Sirvent, Audrey|Paquay de Plater, Ludmilla|Edmonds, Thomas|David, Geraldine|Jan, Michel|de Montrion, Catherine|Coge, Francis|Leonce, Stephane|Burbridge, Michael|Bruno, Alain|Boutin, Jean A|Lockhart, Brian|Roche, Serge|Cru
PMID: 21390316
Journal: J Proteome Res. 2011 Jul 1;10(7):3200-11.
Title: Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer.
Author: Organ, Shawna L|Tong, Jiefei|Taylor, Paul|St-Germain, Jonathan R|Navab, Roya|Moran, Michael F|Tsao, Ming-Sound
PMID: 21609022
Journal: Clin Cancer Res. 2011 Sep 1;17(17):5546-52.
Title: Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
Author: Montero, Juan Carlos|Seoane, Samuel|Ocana, Alberto|Pandiella, Atanasio
PMID: 21670084
Journal: J Mol Signal. 2011 Jul 20;6:7.
Title: Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells.
Author: Nautiyal, Jyoti|Kanwar, Shailender S|Yu, Yingjie|Majumdar, Adhip Pn
PMID: 21774804
Journal: Apoptosis. 2011 Dec;16(12):1285-94.
Title: The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU.
Author: Kline, Christina Leah B|Irby, Rosalyn B
PMID: 21910008
Journal: Cancer Res. 2011 Nov 15;71(22):7010-20.
Title: ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression.
Author: Kim, Sun-Hee|Park, Yun-Yong|Kim, Sang-Wook|Lee, Ju-Seog|Wang, Dingzhi|DuBois, Raymond N
PMID: 21937683
Journal: Eur J Pharmacol. 2011 Dec 5;671(1-3):7-17.
Title: Lysophosphatidic acid induces a migratory phenotype through a crosstalk between RhoA-Rock and Src-FAK signalling in colon cancer cells.
Author: Leve, Fernanda|Marcondes, Taline Guimaraes Correa|Bastos, Lilian Goncalves R|Rabello, Sarah Vieira|Tanaka, Marcelo Neves|Morgado-Diaz, Jose Andres
PMID: 21968138
Journal: J Biol Chem. 2011 Dec 9;286(49):42303-15.
Title: Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734.
Author: Wortmann, Andreas|He, Yaowu|Christensen, Melinda E|Linn, Mayla|Lumley, John W|Pollock, Pamela M|Waterhouse, Nigel J|Hooper, John D
PMID: 21994943
Journal: Int J Mol Epidemiol Genet. 2011;2(4):300-15. Epub 2011 Dec 3.
Title: Genetic variability in EGFR, Src and HER2 and risk of colorectal adenoma and cancer.
Author: Poole, Elizabeth M|Curtin, Karen|Hsu, Li|Kulmacz, Richard J|Duggan, David J|Makar, Karen W|Xiao, Liren|Carlson, Christopher S|Slattery, Martha L|Caan, Bette J|Potter, John D|Ulrich, Cornelia M
PMID: 22199994
Journal: Chin J Cancer Res. 2011 Sep;23(3):229-31.
Title: SRC is dephosphorylated at tyrosine 530 in human colon carcinomas.
Author: Zhu, Shudong|Bjorge, Jeffrey D|Fujita, Donald J
PMID: 23467908
Journal: Oncogene. 2012 Jan 19;31(3):376-89.
Title: Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis.
Author: Swaminathan, G|Cartwright, C A
PMID: 21685945
Journal: Oncogene. 2012 Mar 8;31(10):1217-27.
Title: Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death.
Author: Ratushny, V|Pathak, H B|Beeharry, N|Tikhmyanova, N|Xiao, F|Li, T|Litwin, S|Connolly, D C|Yen, T J|Weiner, L M|Godwin, A K|Golemis, E A
PMID: 21785464
Journal: Oncogene. 2012 Mar 29;31(13):1623-35.
Title: MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression.
Author: Oneyama, C|Morii, E|Okuzaki, D|Takahashi, Y|Ikeda, J|Wakabayashi, N|Akamatsu, H|Tsujimoto, M|Nishida, T|Aozasa, K|Okada, M
PMID: 21860426
Journal: Int J Oncol. 2012 Apr;40(4):1267-76.
Title: Blockade of irradiation-induced autophagosome formation impairs proliferation but does not enhance cell death in HCT-116 human colorectal carcinoma cells.
Author: de Albuquerque-Xavier, Ana Cristina|Bastos, Lilian Goncalves R|de Freitas, Julio Cesar Madureira Jr|Leve, Fernanda|de Souza, Waldemir Fernandez|de Araujo, Wallace Martins|Wanderley, Joao Luiz Mendes|Tanaka, Marcelo Neves|de Souza, Wanderley|Morgado-Diaz,
PMID: 22246348
Journal: FASEB J. 2012 May;26(5):2049-59.
Title: A crucial role for Nox 1 in redox-dependent regulation of Wnt-beta-catenin signaling.
Author: Kajla, Seheli|Mondol, Abdus S|Nagasawa, Atsushi|Zhang, Yugen|Kato, Masayoshi|Matsuno, Kuniharu|Yabe-Nishimura, Chihiro|Kamata, Tohru
PMID: 22278940
Journal: Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2302-7.
Title: Src tyrosine kinase phosphorylation of nuclear receptor HNF4alpha correlates with isoform-specific loss of HNF4alpha in human colon cancer.
Author: Chellappa, Karthikeyani|Jankova, Lucy|Schnabl, Jake M|Pan, Songqin|Brelivet, Yann|Fung, Caroline L-S|Chan, Charles|Dent, Owen F|Clarke, Stephen J|Robertson, Graham R|Sladek, Frances M
PMID: 22308320
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G1006-15.
Title: Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation.
Author: Xie, Guofeng|Peng, Zhongsheng|Raufman, Jean-Pierre
PMID: 22361730
Journal: Cancer Res. 2012 Jun 1;72(11):2780-90.
Title: High expression of IL-13 receptor alpha2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis.
Author: Barderas, Rodrigo|Bartolome, Ruben A|Fernandez-Acenero, Maria Jesus|Torres, Sofia|Casal, J Ignacio
PMID: 22505647
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G111-9.
Title: Epidermal growth factor receptor transactivation is required for proteinase-activated receptor-2-induced COX-2 expression in intestinal epithelial cells.
Author: Hirota, Christina L|Moreau, France|Iablokov, Vadim|Dicay, Michael|Renaux, Bernard|Hollenberg, Morley D|MacNaughton, Wallace K
PMID: 22517768
Journal: Biochimie. 2012 Aug;94(8):1754-63.
Title: The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells.
Author: Limami, Youness|Pinon, Aline|Leger, David Yannick|Pinault, Emilie|Delage, Christiane|Beneytout, Jean-Louis|Simon, Alain|Liagre, Bertrand
PMID: 22521508
Journal: Clin Cancer Res. 2012 May 1;18(9):2704-14.
Title: Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib.
Author: Arcaroli, John J|Quackenbush, Kevin S|Powell, Rebecca W|Pitts, Todd M|Spreafico, Anna|Varella-Garcia, Marileila|Bemis, Lynne|Tan, Aik Choon|Reinemann, Jaclyn M|Touban, Basel M|Dasari, Arvind|Eckhardt, S Gail|Messersmith, Wells A
PMID: 22553375
Journal: Biol Pharm Bull. 2012;35(7):1054-63.
Title: (1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-olide, a cembrenolide diterpene from soft coral Lobophytum sp., inhibits growth and induces apoptosis in human colon cancer cells through reactive oxygen species generation.
Author: Hong, Ji-Young|Boo, Hye-Jin|Kang, Jung-Il|Kim, Min-Kyoung|Yoo, Eun-Sook|Hyun, Jin-Won|Koh, Young-Sang|Kim, Gi Young|Maeng, Young Hee|Hyun, Chang Lim|Chang, Weon Young|Kim, Young Ho|Kim, Young Ree|Kang, Hee-Kyoung
PMID: 22791152
Journal: Asian Pac J Cancer Prev. 2012;13(5):2235-40.
Title: c-Src antisense complexed with PAMAM denderimes decreases of c-Src expression and EGFR-dependent downstream genes in the human HT-29 colon cancer cell line.
Author: Nourazarian, Ali Reza|Pashaei-Asl, Roghiyeh|Omidi, Yadollah|Najar, Ahmad Gholamhoseinian
PMID: 22901200
Journal: Carcinogenesis. 2012 Dec;33(12):2538-47.
Title: Claudin-1 expression confers resistance to anoikis in colon cancer cells in a Src-dependent manner.
Author: Singh, Amar B|Sharma, Ashok|Dhawan, Punita
PMID: 22941059
Journal: Mol Cell Proteomics. 2012 Dec;11(12):1937-50.
Title: Analysis of SRC oncogenic signaling in colorectal cancer by stable isotope labeling with heavy amino acids in mouse xenografts.
Author: Sirvent, Audrey|Vigy, Oana|Orsetti, Beatrice|Urbach, Serge|Roche, Serge
PMID: 23023324
Journal: PLoS One. 2012;7(10):e48461.
Title: Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis.
Author: Peng, Zhongsheng|Raufman, Jean-Pierre|Xie, Guofeng
PMID: 23119029
Journal: Asian Pac J Cancer Prev. 2012;13(9):4751-6.
Title: Combined EGFR and c-Src antisense oligodeoxynucleotides encapsulated with PAMAM Denderimers inhibit HT-29 colon cancer cell proliferation.
Author: Nourazarian, Ali Reza|Najar, Ahmad Gholamhoseinian|Farajnia, Safar|Khosroushahi, Ahmad Yari|Pashaei-Asl, Roghiyeh|Omidi, Yadollah
PMID: 23167414
Journal: J Transl Med. 2012 Dec 24;10:254.
Title: Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo.
Author: Fan, Chung-Wei|Chen, Chun-Yu|Chen, Kuei-Tien|Shen, Chia-Rui|Kuo, Yung-Bin|Chen, Ya-Shan|Chou, Yeh-Pin|Wei, Wei-Shan|Chan, Err-Cheng
PMID: 23259795
Journal: Oncogene. 2013 Apr 4;32(14):1863-8.
Title: Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.
Author: Baker, A-M|Bird, D|Lang, G|Cox, T R|Erler, J T
PMID: 22641216
Journal: Oncogene. 2013 Apr 18;32(16):2087-95.
Title: Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14.
Author: Zhang, P|Guo, A|Possemato, A|Wang, C|Beard, L|Carlin, C|Markowitz, S D|Polakiewicz, R D|Wang, Z
PMID: 22710723
Journal: J Crohns Colitis. 2013 Jun;7(5):403-11.
Title: Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer.
Author: Gillespie, Earl|Leeman, Susan E|Watts, Luisa A|Coukos, Jennifer A|O'Brien, Michael J|Cerda, Sandra R|Farraye, Francis A|Stucchi, Arthur F
PMID: 22921465
Journal: J Steroid Biochem Mol Biol. 2013 Jul;136:120-4.
Title: Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1alpha,25-dihydroxyvitamin D3-responsive genes.
Author: Meyer, Mark B|Pike, J Wesley
PMID: 22944139
Journal: Curr Pharm Des. 2013;19(5):958-64.
Title: Irinotecan resistance is accompanied by upregulation of EGFR and Src signaling in human cancer models.
Author: Petitprez, Amelie|Larsen, Annette K
PMID: 22973964
Journal: Oncogene. 2013 Sep 5;32(36):4304-12.
Title: Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
Author: Zheng, Y|Gierut, J|Wang, Z|Miao, J|Asara, J M|Tyner, A L
PMID: 23027128
Journal: Cancer Biol Ther. 2013 Feb;14(2):175-83.
Title: Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migration.
Author: Ierano, Caterina|Basseville, Agnes|To, Kenneth K W|Zhan, Zhirong|Robey, Robert W|Wilkerson, Julia|Bates, Susan E|Scala, Stefania
PMID: 23192271
Journal: Anticancer Drugs. 2013 Mar;24(3):237-50.
Title: Dual inhibition of alphaV integrins and Src kinase activity as a combination therapy strategy for colorectal cancer.
Author: Jia, Jingquan|Starodub, Alex|Cushman, Ian|Liu, Yingmiao|Marshall, Deborah J|Hurwitz, Herbert I|Nixon, Andrew B
PMID: 23275294
Journal: Bioorg Med Chem. 2013 Feb 1;21(3):693-702.
Title: Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists.
Author: Batie, Shane|Lee, Jamie H|Jama, Rabia A|Browder, Drew O|Montano, Luis A|Huynh, Chanh C|Marcus, Lisa M|Tsosie, Dorian G|Mohammed, Zeynab|Trang, Vu|Marshall, Pamela A|Jurutka, Peter W|Wagner, Carl E
PMID: 23276449
Journal: Int J Cancer. 2013 Jul;133(1):43-57.
Title: Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis.
Author: Basu Roy, Upal K|Henkhaus, Rebecca S|Loupakis, Fotios|Cremolini, Chiara|Gerner, Eugene W|Ignatenko, Natalia A
PMID: 23280667
Journal: Cell Rep. 2013 Jan 31;3(1):173-85.
Title: DCC expression by neurons regulates synaptic plasticity in the adult brain.
Author: Horn, Katherine E|Glasgow, Stephen D|Gobert, Delphine|Bull, Sarah-Jane|Luk, Tamarah|Girgis, Jacklyn|Tremblay, Marie-Eve|McEachern, Danielle|Bouchard, Jean-Francois|Haber, Michael|Hamel, Edith|Krimpenfort, Paul|Murai, Keith K|Berns, Anton|Doucet, Guy|Chapm
PMID: 23291093
Journal: Food Chem Toxicol. 2013 May;55:424-33.
Title: Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells.
Author: Park, Eun-Jung|Chung, Hwa-Jin|Park, Hyen Joo|Kim, Gi Dae|Ahn, Yong-Hyun|Lee, Sang Kook
PMID: 23333577
Journal: PLoS One. 2013;8(2):e57218.
Title: Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways.
Author: Shakibaei, Mehdi|Mobasheri, Ali|Lueders, Cora|Busch, Franziska|Shayan, Paviz|Goel, Ajay
PMID: 23451189
Journal: PLoS One. 2013;8(3):e59563.
Title: CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a.
Author: Muppala, Santoshi|Mudduluru, Giridhar|Leupold, Jorg H|Buergy, Daniel|Sleeman, Jonathan P|Allgayer, Heike
PMID: 23533633
Journal: Proteomics. 2013 May;13(10-11):1672-86.
Title: Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.
Author: Ji, Hong|Greening, David W|Barnes, Thomas W|Lim, Justin W|Tauro, Bow J|Rai, Alin|Xu, Rong|Adda, Christopher|Mathivanan, Suresh|Zhao, Wei|Xue, Yanhong|Xu, Tao|Zhu, Hong-Jian|Simpson, Richard J
PMID: 23585443
Journal: PLoS One. 2013 May 17;8(5):e64309.
Title: Src-mediated phosphorylation of the tyrosine phosphatase PRL-3 is required for PRL-3 promotion of Rho activation, motility and invasion.
Author: Fiordalisi, James J|Dewar, Brian J|Graves, Lee M|Madigan, James P|Cox, Adrienne D
PMID: 23691193
Journal: PLoS One. 2013 May 16;8(5):e63695.
Title: FGFR4 role in epithelial-mesenchymal transition and its therapeutic value in colorectal cancer.
Author: Pelaez-Garcia, Alberto|Barderas, Rodrigo|Torres, Sofia|Hernandez-Varas, Pablo|Teixido, Joaquin|Bonilla, Felix|de Herreros, Antonio Garcia|Casal, J Ignacio
PMID: 23696849
Journal: Cancer Biol Ther. 2013 Aug;14(8):761-72.
Title: Focal adhesion kinase autophosphorylation inhibition decreases colon cancer cell growth and enhances the efficacy of chemotherapy.
Author: Heffler, Melissa|Golubovskaya, Vita M|Dunn, Kelli M Bullard|Cance, William
PMID: 23792569
Journal: Cancer Res. 2013 Sep 1;73(17):5473-84.
Title: Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and beta-catenin.
Author: Saud, Shakir M|Young, Matthew R|Jones-Hall, Yava L|Ileva, Lilia|Evbuomwan, Moses O|Wise, Jennifer|Colburn, Nancy H|Kim, Young S|Bobe, Gerd
PMID: 23824743
Journal: Oncotarget. 2013 Jul;4(7):1037-49.
Title: Blockade of the PDGFR family together with SRC leads to diminished proliferation of colorectal cancer cells.
Author: Kaulfuss, Silke|Seemann, Henning|Kampe, Rovena|Meyer, Julia|Dressel, Ralf|Konig, Britta|Scharf, Jens-Gerd|Burfeind, Peter
PMID: 23900414
Journal: BMC Gastroenterol. 2013 Aug 9;13:126.
Title: High expression level and nuclear localization of Sam68 are associated with progression and poor prognosis in colorectal cancer.
Author: Liao, Wen-Ting|Liu, Jun-Ling|Wang, Zheng-Gen|Cui, Yan-Mei|Shi, Ling|Li, Ting-Ting|Zhao, Xiao-Hui|Chen, Xiu-Ting|Ding, Yan-Qing|Song, Li-Bing
PMID: 23937454
Journal: Cell Commun Signal. 2013 Aug 15;11:59.
Title: Activation state-dependent interaction between Galphaq subunits and the Fhit tumor suppressor.
Author: Zuo, Hao|Chan, Grace P W|Zhu, Jing|Yeung, Wendy W S|Chan, Anthony S L|Ammer, Hermann|Wong, Yung H
PMID: 23947369
Journal: Am J Pathol. 2013 Nov;183(5):1667-78.
Title: Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells.
Author: Abe, Hitoshi|Mochizuki, Satsuki|Ohara, Kentaro|Ueno, Mari|Ochiai, Hiroki|Kitagawa, Yuko|Hino, Okio|Sato, Hiroshi|Okada, Yasunori
PMID: 24007880
Journal: PLoS One. 2013 Nov 11;8(11):e80300.
Title: MiR-424/503-mediated Rictor upregulation promotes tumor progression.
Author: Oneyama, Chitose|Kito, Yoriko|Asai, Rei|Ikeda, Jun-ichiro|Yoshida, Takuya|Okuzaki, Daisuke|Kokuda, Rie|Kakumoto, Kyoko|Takayama, Ken-ichi|Inoue, Satoshi|Morii, Eiichi|Okada, Masato
PMID: 24244675
Journal: PLoS One. 2013 Nov 18;8(11):e79335.
Title: CRF2 signaling is a novel regulator of cellular adhesion and migration in colorectal cancer cells.
Author: Ducarouge, Benjamin|Pelissier-Rota, Marjolaine|Laine, Michele|Cristina, Nadine|Vachez, Yvan|Scoazec, Jean-Yves|Bonaz, Bruno|Jacquier-Sarlin, Muriel
PMID: 24260200
Journal: PLoS One. 2013 Nov 8;8(11):e80207.
Title: Global phosphotyrosine proteomics identifies PKCdelta as a marker of responsiveness to Src inhibition in colorectal cancer.
Author: McKinley, Eliot T|Liu, Huiling|McDonald, W Hayes|Luo, Weifeng|Zhao, Ping|Coffey, Robert J|Hanks, Steven K|Manning, H Charles
PMID: 24260357
Journal: Oncogene. 2014 Apr 17;33(16):2123-33.
Title: Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.
Author: Cardoso, A P|Pinto, M L|Pinto, A T|Oliveira, M I|Pinto, M T|Goncalves, R|Relvas, J B|Figueiredo, C|Seruca, R|Mantovani, A|Mareel, M|Barbosa, M A|Oliveira, M J
PMID: 23644655
Journal: Int J Cancer. 2014 May 1;134(9):2019-29.
Title: The molecular rationale of Src inhibition in colorectal carcinomas.
Author: Gargalionis, Antonios N|Karamouzis, Michalis V|Papavassiliou, Athanasios G
PMID: 23733480
Journal: Clin Colorectal Cancer. 2014 Mar;13(1):5-13.
Title: The role of Src in colon cancer and its therapeutic implications.
Author: Chen, Jiezhong|Elfiky, Aymen|Han, Mei|Chen, Chen|Saif, M Wasif
PMID: 24361441
Journal: J Biol Chem. 2014 Feb 28;289(9):5904-13.
Title: Protein-tyrosine phosphatase 4A3 (PTP4A3) promotes vascular endothelial growth factor signaling and enables endothelial cell motility.
Author: Zimmerman, Mark W|McQueeney, Kelley E|Isenberg, Jeffrey S|Pitt, Bruce R|Wasserloos, Karla A|Homanics, Gregg E|Lazo, John S
PMID: 24403062
Journal: Cell Death Dis. 2014 Jan 9;5:e983.
Title: Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation.
Author: Fu, Y|Yang, G|Zhu, F|Peng, C|Li, W|Li, H|Kim, H-G|Bode, A M|Dong, Z|Dong, Z
PMID: 24407236
Journal: Nat Commun. 2014;5:3159.
Title: SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.
Author: Naudin, Cecile|Sirvent, Audrey|Leroy, Cedric|Larive, Romain|Simon, Valerie|Pannequin, Julie|Bourgaux, Jean-Francois|Pierre, Josiane|Robert, Bruno|Hollande, Frederic|Roche, Serge
PMID: 24457997
Journal: Hepatology. 2014 Jun;59(6):2238-50.
Title: Functional genomics identified a novel protein tyrosine phosphatase receptor type F-mediated growth inhibition in hepatocarcinogenesis.
Author: Bera, Rabindranath|Chiou, Chih-Yung|Yu, Ming-Chin|Peng, Jei-Ming|He, Chung-Ru|Hsu, Chih-Yun|Huang, Hsiao-Ling|Ho, Uda Y|Lin, Shi-Ming|Lin, Yu-Jr|Hsieh, Sen-Yung
PMID: 24470239
Journal: Int J Oncol. 2014 Apr;44(4):1309-15.
Title: Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
Author: Park, Ki-Woong|Kundu, Juthika|Chae, In-Gyeong|Kim, Do-Hee|Yu, Mi-Hee|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24481553
Journal: Cancer Res. 2014 Apr 1;74(7):2062-72.
Title: Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-alpha: impact on gastrointestinal cancers driven by secondary bile acids.
Author: Nagathihalli, Nagaraj S|Beesetty, Yugandhar|Lee, Wooin|Washington, M Kay|Chen, Xi|Lockhart, A Craig|Merchant, Nipun B
PMID: 24520077
Journal: Int J Mol Sci. 2014 Apr 4;15(4):5838-51.
Title: Cetuximab-induced MET activation acts as a novel resistance mechanism in colon cancer cells.
Author: Song, Na|Liu, Shizhou|Zhang, Jingdong|Liu, Jing|Xu, Ling|Liu, Yunpeng|Qu, Xiujuan
PMID: 24714091
Journal: Cancer Cell. 2014 Apr 14;25(4):469-83.
Title: MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.
Author: Valeri, Nicola|Braconi, Chiara|Gasparini, Pierluigi|Murgia, Claudio|Lampis, Andrea|Paulus-Hock, Viola|Hart, Jonathan R|Ueno, Lynn|Grivennikov, Sergei I|Lovat, Francesca|Paone, Alessio|Cascione, Luciano|Sumani, Khlea M|Veronese, Angelo|Fabbri, Muller|Caras
PMID: 24735923
Journal: EMBO J. 2014 Jul 1;33(13):1474-91.
Title: c-Src drives intestinal regeneration and transformation.
Author: Cordero, Julia B|Ridgway, Rachel A|Valeri, Nicola|Nixon, Colin|Frame, Margaret C|Muller, William J|Vidal, Marcos|Sansom, Owen J
PMID: 24788409
Journal: Oncol Rep. 2014 Aug;32(2):821-8.
Title: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase.
Author: Kundu, Juthika|Choi, Bu Young|Jeong, Chul-Ho|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24890449
Journal: Med Sci (Paris). 2014 May;30(5):558-66.
Title: [Analysis of oncogenic signaling induced by tyrosine kinases in tumors by SILAC-based quantitative proteomic approach].
Author: Sirvent, Audrey|Urbach, Serge|Roche, Serge
PMID: 24939544
Journal: Oxid Med Cell Longev. 2014;2014:193523.
Title: PELP1 suppression inhibits colorectal cancer through c-Src downregulation.
Author: Ning, Zhifeng|Zhang, Youzhi|Chen, Hanwei|Wu, Jiliang|Song, Tieshan|Wu, Qian|Liu, Fuxing
PMID: 24967003
Journal: Nature. 2014 Sep 18;513(7518):382-7.
Title: Proteogenomic characterization of human colon and rectal cancer.
Author: Zhang, Bing|Wang, Jing|Wang, Xiaojing|Zhu, Jing|Liu, Qi|Shi, Zhiao|Chambers, Matthew C|Zimmerman, Lisa J|Shaddox, Kent F|Kim, Sangtae|Davies, Sherri R|Wang, Sean|Wang, Pei|Kinsinger, Christopher R|Rivers, Robert C|Rodriguez, Henry|Townsend, R Reid|Ellis,
PMID: 25043054
Journal: Toxicol Appl Pharmacol. 2014 Dec 1;281(2):166-73.
Title: Dioscin inhibits colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK signaling pathways.
Author: Tong, Qingyi|Qing, Yong|Wu, Yang|Hu, Xiaojuan|Jiang, Lei|Wu, Xiaohua
PMID: 25111127
Journal: PLoS One. 2014 Aug 14;9(8):e104891.
Title: Epidermal growth factor stimulates nuclear factor-kappaB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.
Author: Lien, Gi-Shih|Wu, Ming-Shun|Bien, Mauo-Ying|Chen, Chien-Hsin|Lin, Chien-Huang|Chen, Bing-Chang
PMID: 25122478
Journal: BMC Cancer. 2014 Sep 10;14:660.
Title: Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer.
Author: Kopetz, Scott|Morris, Van K|Parikh, Nila|Overman, Michael J|Jiang, Zhi-Qin|Maru, Dipen|Elvin, Paul|Gallick, Gary
PMID: 25208577
Journal: Cell Physiol Biochem. 2014;34(4):1402-12.
Title: Membrane androgen receptor down-regulates c-src-activity and beta-catenin transcription and triggers GSK-3beta-phosphorylation in colon tumor cells.
Author: Gu, Shuchen|Honisch, Sabina|Kounenidakis, Michalis|Alkahtani, Saad|Alarifi, Saud|Alevizopoulos, Konstantinos|Stournaras, Christos|Lang, Florian
PMID: 25301365
Journal: Oncotarget. 2014 Oct 30;5(20):10070-83.
Title: The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling.
Author: Asbagh, Layka Abbasi|Vazquez, Iria|Vecchione, Loredana|Budinska, Eva|De Vriendt, Veerle|Baietti, Maria Francesca|Steklov, Mikhail|Jacobs, Bart|Hoe, Nicholas|Singh, Sharat|Imjeti, Naga-Sailaja|Zimmermann, Pascale|Sablina, Anna|Tejpar, Sabine
PMID: 25301722
Journal: Asian Pac J Cancer Prev. 2014;15(21):9271-5.
Title: Prognostic analysis of schistosomal rectal cancer.
Author: Wang, Meng|Zhang, Yuan-Chuan|Yang, Xu-Yang|Wang, Zi-Qiang
PMID: 25422211
Journal: Cell Death Differ. 2015 May;22(5):779-89.
Title: Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer.
Author: Wu, D-W|Huang, C-C|Chang, S-W|Chen, T-H|Lee, H
PMID: 25323586
Journal: J Cell Mol Med. 2015 Feb;19(2):383-95.
Title: A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway.
Author: Dai, Fujun|Chen, Yihua|Huang, Li|Wang, Jinhua|Zhang, Tao|Li, Jingjie|Tong, Weiguang|Liu, Mingyao|Yi, Zhengfang
PMID: 25351103
Journal: J Cell Mol Med. 2015 Feb;19(2):474-84.
Title: Diallyl trisulfide inhibits migration, invasion and angiogenesis of human colon cancer HT-29 cells and umbilical vein endothelial cells, and suppresses murine xenograft tumour growth.
Author: Lai, Kuang-Chi|Hsu, Shu-Chun|Yang, Jai-Sing|Yu, Chien-Chih|Lein, Jin-Cherng|Chung, Jing-Gung
PMID: 25403643
Journal: Oncotarget. 2015 Feb 20;6(5):3123-35.
Title: Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/beta-catenin pathway.
Author: Zhang, Qian-Qian|Zhou, Da-Lei|Lei, Yan|Zheng, Li|Chen, Sheng-Xia|Gou, Hong-Ju|Gu, Qu-Liang|He, Xiao-Dong|Lan, Tian|Qi, Cui-Ling|Li, Jiang-Chao|Ding, Yan-Qing|Qiao, Liang|Wang, Li-Jing
PMID: 25605242
Journal: Cancer Lett. 2015 Apr 10;359(2):218-25.
Title: PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer.
Author: Liu, Hongbing|Wu, Ying|Zhu, Suhua|Liang, Wenjun|Wang, Zhaofeng|Wang, Yunfen|Lv, Tangfeng|Yao, Yanwen|Yuan, Dongmei|Song, Yong
PMID: 25617799
Journal: Phytomedicine. 2015 Jan 15;22(1):103-10.
Title: Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling.
Author: Guan, Ying-Yun|Liu, Hai-Jun|Luan, Xin|Xu, Jian-Rong|Lu, Qin|Liu, Ya-Rong|Gao, Yun-Ge|Zhao, Mei|Chen, Hong-Zhuan|Fang, Chao
PMID: 25636878
Journal: Nature. 2015 Mar 5;519(7541):57-62.
Title: A gp130-Src-YAP module links inflammation to epithelial regeneration.
Author: Taniguchi, Koji|Wu, Li-Wha|Grivennikov, Sergei I|de Jong, Petrus R|Lian, Ian|Yu, Fa-Xing|Wang, Kepeng|Ho, Samuel B|Boland, Brigid S|Chang, John T|Sandborn, William J|Hardiman, Gary|Raz, Eyal|Maehara, Yoshihiko|Yoshimura, Akihiko|Zucman-Rossi, Jessica|Guan
PMID: 25731159
Journal: Am J Pathol. 2015 Apr;185(4):1135-44.
Title: Methionine adenosyltransferase 2B-GIT1 complex serves as a scaffold to regulate Ras/Raf/MEK1/2 activity in human liver and colon cancer cells.
Author: Peng, Hui|Li, Tony W H|Yang, Heping|Moyer, Mary P|Mato, Jose M|Lu, Shelly C
PMID: 25794709
Journal: Int J Biochem Cell Biol. 2015 Jul;64:45-57.
Title: Human enhancer of filamentation 1-induced colorectal cancer cell migration: Role of serine phosphorylation and interaction with the breast cancer anti-estrogen resistance 3 protein.
Author: Ibrahim, Rama|Lemoine, Antoinette|Bertoglio, Jacques|Raingeaud, Joel
PMID: 25817040
Journal: Int J Oncol. 2015;46(6):2621-8.
Title: Inhibitory effects of proton beam irradiation on integrin expression and signaling pathway in human colon carcinoma HT29 cells.
Author: Ha, Byung Geun|Park, Jung-Eun|Cho, Hyun-Jung|Lim, Young-Bin|Shon, Yun Hee
PMID: 25845382
Journal: BMC Cancer. 2015 Apr 12;15:275.
Title: Loss of AF-6/afadin induces cell invasion, suppresses the formation of glandular structures and might be a predictive marker of resistance to chemotherapy in endometrial cancer.
Author: Yamamoto, Takuro|Mori, Taisuke|Sawada, Morio|Matsushima, Hiroshi|Ito, Fumitake|Akiyama, Makoto|Kitawaki, Jo
PMID: 25879875
Journal: J Transl Med. 2015 Feb 12;13:57.
Title: Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib.
Author: Wong, Andrea Li Ann|Lim, Joline Si Jing|Sinha, Arvind|Gopinathan, Anil|Lim, Robert|Tan, Chee-Seng|Soh, Thomas|Venkatesh, Sudhakar|Titin, Christina|Sapari, Nur Sabrina|Lee, Soo-Chin|Yong, Wei-Peng|Tan, David Shao Ping|Pang, Brendan|Wang, Ting-Ting|Zee, Yin
PMID: 25889309
Journal: Cancer Res. 2015 Jun 15;75(12):2434-44.
Title: IL13 Receptor alpha2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.
Author: Bartolome, Ruben A|Garcia-Palmero, Irene|Torres, Sofia|Lopez-Lucendo, Maria|Balyasnikova, Irina V|Casal, J Ignacio
PMID: 25896327
Journal: BMC Cancer. 2015 Jun 5;15:456.
Title: Matrix metalloproteases as maestros for the dual role of LPS- and IL-10-stimulated macrophages in cancer cell behaviour.
Author: Cardoso, Ana P|Pinto, Marta L|Pinto, Ana T|Pinto, Marta T|Monteiro, Catia|Oliveira, Marta I|Santos, Susana G|Relvas, Joao B|Seruca, Raquel|Mantovani, Alberto|Mareel, Marc|Barbosa, Mario A|Oliveira, Maria J
PMID: 26043921
Journal: Sci Rep. 2015 Jun 9;5:11187.
Title: Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRalpha/c-SRC/ERK1/2/NFkappaB/TP53 pathway: in vitro and in vivo studies.
Author: Kuo, Chun-Ting|Chang, Chieh|Lee, Wen-Sen
PMID: 26056802
Journal: Exp Cell Res. 2015 Oct 15;338(1):10-21.
Title: Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells.
Author: Coskun, Deniz|Obakan, Pinar|Arisan, Elif Damla|Coker-Gurkan, Ajda|Palavan-Unsal, Narcin
PMID: 26318418
Journal: Cell Death Differ. 2015 Oct;22(10):1700-13.
Title: Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer.
Author: Francescangeli, F|Contavalli, P|De Angelis, M L|Baiocchi, M|Gambara, G|Pagliuca, A|Fiorenzano, A|Prezioso, C|Boe, A|Todaro, M|Stassi, G|Castro, N P|Watanabe, K|Salomon, D S|De Maria, R|Minchiotti, G|Zeuner, A
PMID: 26343543
Journal: Bioorg Chem. 2015 Dec;63:1-12.
Title: Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran-pyrazole derivatives as anticancer agents.
Author: Abd El-Karim, Somaia S|Anwar, Manal M|Mohamed, Neama A|Nasr, Tamer|Elseginy, Samia A
PMID: 26368040
Journal: Oncotarget. 2015 Oct 20;6(32):32622-33.
Title: Acquired resistance to 5-fluorouracil via HSP90/Src-mediated increase in thymidylate synthase expression in colon cancer.
Author: Ahn, Ji-Young|Lee, Ji-Sun|Min, Hye-Young|Lee, Ho-Young
PMID: 26416450
Journal: Clin Cancer Drugs. 2015 Feb;2(2):100-111.
Title: Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies.
Author: Johnson, Benny|Mahadevan, Daruka
PMID: 27595061
Journal: Mol Carcinog. 2016 Jun;55(6):1096-110.
Title: Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells.
Author: Kim, Do-Hee|Park, Ki-Woong|Chae, In Gyeong|Kundu, Juthika|Kim, Eun-Hee|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 26152521
Journal: Oncogene. 2016 Jun 9;35(23):2991-3003.
Title: SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.
Author: Barbachano, A|Fernandez-Barral, A|Pereira, F|Segura, M F|Ordonez-Moran, P|Carrillo-de Santa Pau, E|Gonzalez-Sancho, J M|Hanniford, D|Martinez, N|Costales-Carrera, A|Real, F X|Palmer, H G|Rojas, J M|Hernando, E|Munoz, A
PMID: 26455323
Journal: Cancer Sci. 2016 Jan;107(1):28-35.
Title: MicroRNA-27b suppresses tumor progression by regulating ARFGEF1 and focal adhesion signaling.
Author: Matsuyama, Rei|Okuzaki, Daisuke|Okada, Masato|Oneyama, Chitose
PMID: 26473412
Journal: Cell Death Differ. 2016 Apr;23(4):707-22.
Title: DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.
Author: Alam, S K|Yadav, V K|Bajaj, S|Datta, A|Dutta, S K|Bhattacharyya, M|Bhattacharya, S|Debnath, S|Roy, S|Boardman, L A|Smyrk, T C|Molina, J R|Chakrabarti, S|Chowdhury, S|Mukhopadhyay, D|Roychoudhury, S
PMID: 26494468
Journal: Am J Pathol. 2016 Apr;186(4):899-911.
Title: Dynamic Change of Polarity in Primary Cultured Spheroids of Human Colorectal Adenocarcinoma and Its Role in Metastasis.
Author: Okuyama, Hiroaki|Kondo, Jumpei|Sato, Yumi|Endo, Hiroko|Nakajima, Aya|Piulats, Jose M|Tomita, Yasuhiko|Fujiwara, Takeshi|Itoh, Yu|Mizoguchi, Akira|Ohue, Masayuki|Inoue, Masahiro
PMID: 26878211
Journal: FEBS J. 2016 May;283(9):1669-88.
Title: Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line.
Author: Broecker, Felix|Hardt, Christopher|Herwig, Ralf|Timmermann, Bernd|Kerick, Martin|Wunderlich, Andrea|Schweiger, Michal R|Borsig, Lubor|Heikenwalder, Mathias|Lehrach, Hans|Moelling, Karin
PMID: 26919036
Journal: Oncotarget. 2016 Apr 26;7(17):24483-94.
Title: Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon.
Author: Xiao, Juanjuan|Duan, Qiuhong|Wang, Zhe|Yan, Wei|Sun, Huimin|Xue, Peipei|Fan, Xiaoming|Zeng, Xiaoyu|Chen, Juan|Shao, Chen|Zhu, Feng
PMID: 27016416
Journal: Biochim Biophys Acta. 2016 Jul;1861(7):663-70.
Title: Deoxycholic acid mediates non-canonical EGFR-MAPK activation through the induction of calcium signaling in colon cancer cells.
Author: Centuori, Sara M|Gomes, Cecil J|Trujillo, Jesse|Borg, Jamie|Brownlee, Joshua|Putnam, Charles W|Martinez, Jesse D
PMID: 27086143
Journal: Oncotarget. 2016 May 31;7(22):33111-24.
Title: Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src.
Author: Perez, Marco|Lucena-Cacace, Antonio|Marin-Gomez, Luis Miguel|Padillo-Ruiz, Javier|Robles-Frias, Maria Jose|Saez, Carmen|Garcia-Carbonero, Rocio|Carnero, Amancio
PMID: 27105527
Journal: Ann Coloproctol. 2016 Apr;32(2):58-65.
Title: Prognostic Impact of Microsatellite Instability in Colorectal Cancer Presenting With Mucinous, Signet-Ring, and Poorly Differentiated Cells.
Author: Jung, Sang Hun|Kim, So Hyun|Kim, Jae Hwang
PMID: 27218096
Journal: Bioorg Med Chem Lett. 2016 Aug 15;26(16):3963-7.
Title: Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and beta-catenin signaling pathways.
Author: Jung, Okkeun|Lee, Jongsung|Lee, Yu Jin|Yun, Jung-Mi|Son, Young-Jin|Cho, Jae Youl|Ryou, Chongsuk|Lee, Sang Yeol
PMID: 27422337
Journal: BMC Cancer. 2016 Aug 25;16(1):683.
Title: High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.
Author: Padhan, Narendra|Nordling, Torbjorn E M|Sundstrom, Magnus|Akerud, Peter|Birgisson, Helgi|Nygren, Peter|Nelander, Sven|Claesson-Welsh, Lena
PMID: 27562229
Journal: Oncotarget. 2016 Sep 20;7(38):62559-62571.
Title: Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation.
Author: Jung, Sung-Hoon|Kim, Su-Min|Lee, Choong-Eun
PMID: 27613835
Journal: Oncogenesis. 2016 Sep 12;5(9):e258.
Title: The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial-mesenchymal transition.
Author: Komiya, Y|Onodera, Y|Kuroiwa, M|Nomimura, S|Kubo, Y|Nam, J-M|Kajiwara, K|Nada, S|Oneyama, C|Sabe, H|Okada, M
PMID: 27617642
Journal: Toxicol Appl Pharmacol. 2016 Nov 15;311:106-112.
Title: Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells.
Author: Dai, Jin|Van Wie, Peter G|Fai, Leonard Yenwong|Kim, Donghern|Wang, Lei|Poyil, Pratheeshkumar|Luo, Jia|Zhang, Zhuo
PMID: 27664007
Journal: Oncotarget. 2016 Nov 8;7(45):73402-73413.
Title: Asporin enhances colorectal cancer metastasis through activating the EGFR/src/cortactin signaling pathway.
Author: Wu, Huo|Jing, Xiaoqian|Cheng, Xi|He, Yonggang|Hu, Lei|Wu, Haoxuan|Ye, Feng|Zhao, Ren
PMID: 27705916
Journal: Exp Cell Res. 2016 Nov 15;349(1):119-127.
Title: Claudin-1 promotes TNF-alpha-induced epithelial-mesenchymal transition and migration in colorectal adenocarcinoma cells.
Author: Bhat, Ajaz A|Ahmad, Rizwan|Uppada, SrijayaPrakash B|Singh, Amar B|Dhawan, Punita
PMID: 27742576
Journal: Mol Cancer. 2016 Oct 18;15(1):63.
Title: Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author: Kovaleva, Valentina|Geissler, Anna-Lena|Lutz, Lisa|Fritsch, Ralph|Makowiec, Frank|Wiesemann, Sebastian|Hopt, Ulrich T|Passlick, Bernward|Werner, Martin|Lassmann, Silke
PMID: 27756406
Journal: PLoS One. 2016 Nov 17;11(11):e0166538.
Title: Cell Transformation by PTP1B Truncated Mutants Found in Human Colon and Thyroid Tumors.
Author: Mei, Wenhan|Wang, Kemin|Huang, Jian|Zheng, Xinmin
PMID: 27855221
Journal: Oncotarget. 2016 Nov 22;7(47):78219.
Title: Correction: Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src.
Author: Perez, Marco|Lucena-Cacace, Antonio|Marin-Gomez, Luis Miguel|Padillo-Ruiz, Javier|Robles-Frias, Maria Jose|Saez, Carmen|Garcia-Carbonero, Rocio|Carnero, Amancio
PMID: 28074043
Journal: Oncotarget. 2017 Jul 25;8(30):48782-48793.
Title: Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis.
Author: Zhao, Yiqing|Scott, Anthony|Zhang, Peng|Hao, Yujun|Feng, Xiujing|Somasundaram, Saigopal|Khalil, Ahmad M|Willis, Joseph|Wang, Zhenghe
PMID: 27447856
Journal: Oncotarget. 2017 Apr 4;8(14):22460-22476.
Title: HMGCS2 enhances invasion and metastasis via direct interaction with PPARalpha to activate Src signaling in colorectal cancer and oral cancer.
Author: Chen, Shih-Wen|Chou, Chiang-Ting|Chang, Cheng-Chi|Li, Yue-Ju|Chen, Szu-Ta|Lin, I-Ching|Kok, Sang-Heng|Cheng, Shih-Jung|Lee, Jang-Jaer|Wu, Tai-Sheng|Kuo, Min-Liang|Lin, Been-Ren
PMID: 27816970
Journal: J Cell Physiol. 2017 Jul;232(7):1914-1921.
Title: Cytoplasmic Localization of RUNX3 via Histone Deacetylase-Mediated SRC Expression in Oxidative-Stressed Colon Cancer Cells.
Author: Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Maeng, Young Hee|Hyun, Jin Won
PMID: 27990641
Journal: Biochem J. 2017 Feb 20;474(5):647-665.
Title: Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.
Author: Said, Anan H|Hu, Shien|Abutaleb, Ameer|Watkins, Tonya|Cheng, Kunrong|Chahdi, Ahmed|Kuppusamy, Panjamurthy|Saxena, Neeraj|Xie, Guofeng|Raufman, Jean-Pierre
PMID: 28008134
Journal: Oncogene. 2017 Jun 1;36(22):3104-3118.
Title: Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis.
Author: Agarwal, E|Robb, C M|Smith, L M|Brattain, M G|Wang, J|Black, J D|Chowdhury, S
PMID: 28068324
Journal: Mol Cancer Res. 2017 Jun;15(6):708-713.
Title: Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival.
Author: Ptashkin, Ryan N|Pagan, Carlos|Yaeger, Rona|Middha, Sumit|Shia, Jinru|O'Rourke, Kevin P|Berger, Michael F|Wang, Lu|Cimera, Robert|Wang, Jiajing|Klimstra, David S|Saltz, Leonard|Ladanyi, Marc|Zehir, Ahmet|Hechtman, Jaclyn F
PMID: 28184012
Journal: Oncotarget. 2017 Apr 4;8(14):22674-22684.
Title: MicroRNA-146a promote cell migration and invasion in human colorectal cancer via carboxypeptidase M/src-FAK pathway.
Author: Lu, Di|Yao, Qunyan|Zhan, Cheng|Le-Meng, Zhang|Liu, Hongchun|Cai, Yu|Tu, Chuantao|Li, Xi|Zou, Yanting|Zhang, Shuncai
PMID: 28186967
Journal: Theranostics. 2017 Jan 11;7(3):594-613.
Title: Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity.
Author: Ahn, Hye-Mi|Ryu, Jihye|Song, Jin Myeong|Lee, Yunhee|Kim, Hye-Jin|Ko, Dongjoon|Choi, Inpyo|Kim, Sang Jick|Lee, Jung Weon|Kim, Semi
PMID: 28255353
Journal: Clin Cancer Res. 2017 Aug 1;23(15):4146-4154.
Title: Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author: Parseghian, Christine M|Parikh, Nila U|Wu, Ji Yuan|Jiang, Zhi-Qin|Henderson, Laura|Tian, Feng|Pastor, Brice|Ychou, Marc|Raghav, Kanwal|Dasari, Arvind|Fogelman, David R|Katsiampoura, Anastasia D|Menter, David G|Wolff, Robert A|Eng, Cathy|Overman, Michael J
PMID: 28280091
Journal: Biochem Biophys Res Commun. 2017 May 13;486(4):1062-1068.
Title: Phosphorylation of ETV4 at Ser73 by ERK kinase could block ETV4 ubiquitination degradation in colorectal cancer.
Author: Xiao, Jie|Yang, Shu|Shen, Ping|Wang, Yaxi|Sun, Haimei|Ji, Fengqing|Zhou, Deshan
PMID: 28373072
Journal: Int J Oncol. 2017 May;50(5):1555-1566.
Title: Overexpression of Srcin1 contributes to the growth and metastasis of colorectal cancer.
Author: Zhang, Mengnan|Ma, Feng|Xie, Ruyi|Wu, Yao|Wu, Meiyan|Zhang, Pei|Peng, Ying|Zhao, Jinjun|Xiong, Jing|Li, Aimin|Kequan, Cheng|Zhang, Yali|Liu, Side|Wang, Jide|Chen, Xueqing
PMID: 28393242
Journal: Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1246-1259.
Title: A crosstalk between muscarinic and CRF2 receptors regulates cellular adhesion properties of human colon cancer cells.
Author: Pelissier-Rota, M|Chartier, N T|Bonaz, B|Jacquier-Sarlin, M R
PMID: 28432022
Journal: Chem Biodivers. 2017 May 6.
Title: Systematic Identification and Competitive Disruption of Securin-Binding Partners in the Gene Diversity Space of Human Colorectal Cancer.
Author: Zhang, Yinguang|Zhang, Yongwang|Zhang, Yuxiang
PMID: 28477416
Journal: J Cancer. 2017 Apr 10;8(7):1229-1237.
Title: The Prognostic Value of Tyrosine Kinase SRC Expression in Locally Advanced Rectal Cancer.
Author: Ruhlmann, Felix|Nietert, Manuel|Sprenger, Thilo|Wolff, Hendrik A|Homayounfar, Kia|Middel, Peter|Bohnenberger, Hanibal|Beissbarth, Tim|Ghadimi, B Michael|Liersch, Torsten|Conradi, Lena-Christin
PMID: 28607598
Journal: Am J Pathol. 2017 Jul;187(7):1633-1647.
Title: Differentiation Affects the Release of Exosomes from Colon Cancer Cells and Their Ability to Modulate the Behavior of Recipient Cells.
Author: Lucchetti, Donatella|Calapa, Federica|Palmieri, Valentina|Fanali, Caterina|Carbone, Federica|Papa, Alfredo|De Maria, Ruggero|De Spirito, Marco|Sgambato, Alessandro
PMID: 28619275
Journal: Oncotarget. 2017 Jul 18;8(29):47931-47942.
Title: TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Author: Wang, Yuhui|Wu, Nan|Pang, Bo|Tong, Dandan|Sun, Donglin|Sun, Haiming|Zhang, Chunyu|Sun, Wenjing|Meng, Xiangning|Bai, Jing|Chen, Feng|Geng, Jingshu|Fu, Songbin|Jin, Yan
PMID: 28624785
Journal: Cell Rep. 2017 Jul 25;20(4):999-1015.
Title: A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution.
Author: Anderson, Grace R|Winter, Peter S|Lin, Kevin H|Nussbaum, Daniel P|Cakir, Merve|Stein, Elizabeth M|Soderquist, Ryan S|Crawford, Lorin|Leeds, Jim C|Newcomb, Rachel|Stepp, Priya|Yip, Catherine|Wardell, Suzanne E|Tingley, Jennifer P|Ali, Moiez|Xu, Mengmeng|Ry
PMID: 28746882
Journal: Cell Commun Signal. 2017 Aug 7;15(1):29.
Title: Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine.
Author: Advani, Gahana|Lim, Ya Chee|Catimel, Bruno|Lio, Daisy Sio Seng|Ng, Nadia L Y|Chueh, Anderly C|Tran, Mai|Anasir, Mohd Ishtiaq|Verkade, Heather|Zhu, Hong-Jian|Turk, Benjamin E|Smithgall, Thomas E|Ang, Ching-Seng|Griffin, Michael|Cheng, Heung-Chin
PMID: 28784162
Journal: Exp Ther Med. 2017 Aug;14(2):1357-1366.
Title: Dual inhibition of MET and SRC kinase activity as a combined targeting strategy for colon cancer.
Author: Song, Na|Qu, Xiujuan|Liu, Shizhou|Zhang, Simeng|Liu, Jing|Qu, Jinglei|Zheng, Huachuan|Liu, Yunpeng|Che, Xiaofang
PMID: 28810597
Journal: J Biol Chem. 2017 Oct 13;292(41):17046-17056.
Title: Hypoxia-inducible factor 2alpha (HIF-2alpha) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.
Author: Ma, Xiaoya|Zhang, Huabing|Xue, Xiang|Shah, Yatrik M
PMID: 28848049
Journal: Sci Rep. 2017 Sep 5;7(1):10463.
Title: Deep Phospho- and Phosphotyrosine Proteomics Identified Active Kinases and Phosphorylation Networks in Colorectal Cancer Cell Lines Resistant to Cetuximab.
Author: Abe, Yuichi|Nagano, Maiko|Kuga, Takahisa|Tada, Asa|Isoyama, Junko|Adachi, Jun|Tomonaga, Takeshi
PMID: 28874695
Journal: J Mol Graph Model. 2017 Sep 2;77:259-262.
Title: Transcriptome-wide identification and competitive disruption of sacum-binding partners in human colorectal cancer.
Author: Zhang, Yinguang|Zhang, Yongwang|Zhang, Yuxiang
PMID: 28898789
Journal: Cancer Lett. 2017 Dec 1;410:32-40.
Title: SRC activates TAZ for intestinal tumorigenesis and regeneration.
Author: Byun, Mi Ran|Hwang, Jun-Ha|Kim, A Rum|Kim, Kyung Min|Park, Jung Il|Oh, Ho Taek|Hwang, Eun Sook|Hong, Jeong-Ho
PMID: 28939028
Journal: PLoS One. 2017 Nov 1;12(11):e0187173.
Title: Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.
Author: Scott, Aaron J|Song, Eun-Kee|Bagby, Stacey|Purkey, Alicia|McCarter, Martin|Gajdos, Csaba|Quackenbush, Kevin S|Cross, Benjamin|Pitts, Todd M|Tan, Aik Choon|Eckhardt, S Gail|Fenton, Hubert|Arcaroli, John|Messersmith, Wells A
PMID: 29091939
Journal: Br J Cancer. 2017 Dec 5;117(12):1777-1786.
Title: Nuclear IGF-1R predicts chemotherapy and targeted therapy resistance in metastatic colorectal cancer.
Author: Codony-Servat, Jordi|Cuatrecasas, Miriam|Asensio, Elena|Montironi, Carla|Martinez-Cardus, Anna|Marin-Aguilera, Mercedes|Horndler, Carlos|Martinez-Balibrea, Eva|Rubini, Michele|Jares, Pedro|Reig, Oscar|Victoria, Ivan|Gaba, Lydia|Martin-Richard, Marta|Alons
PMID: 29123263
Journal: Ann Coloproctol. 2017 Dec;33(6):232-238.
Title: Clinical Significance of Signet-Ring-Cell Colorectal Cancer as a Prognostic Factor.
Author: Yun, Sang-Oh|Cho, Yong Beom|Lee, Woo Yong|Kim, Hee Cheol|Yun, Seong Hyeon|Park, Yoon Ah|Huh, Jung Wook
PMID: 29354606
Journal: Gan To Kagaku Ryoho. 2017 Nov;44(12):1757-1759.
Title: [Two Cases of Colorectal Cancer with SRC Amplification].
Author: Oyanagi, Hidehito|Shimada, Yoshifumi|Yagi, Ryoma|Tajima, Yosuke|Ichikawa, Hiroshi|Nakano, Mae|Nakano, Masato|Nagahashi, Masayuki|Sakata, Jun|Kameyama, Hitoshi|Kobayashi, Takashi|Nogami, Hitoshi|Maruyama, Satoshi|Takii, Yasumasa|Wakai, Toshifumi
PMID: 29394766
Journal: Gastroenterol Hepatol Bed Bench. 2017 Winter;10(Suppl1):S93-S101.
Title: Common and differential genetically pathways between ulcerative colitis and colon adenocarcinoma.
Author: Akbari, Somayeh|Hosseini, Mostafa|Rezaei-Tavirani, Majid|Rezaei-Tavirani, Mostafa|Salehi, Seyed Hamid|Alemrajabi, Mahdi|Vaseghi-Maghvan, Padina|Jahani-Sherafat, Somayeh
PMID: 29511478
Journal: Oncogene. 2018 Feb 1;37(5):663-672.
Title: 'MCC' protein interacts with E-cadherin and beta-catenin strengthening cell-cell adhesion of HCT116 colon cancer cells.
Author: Benthani, F A|Herrmann, D|Tran, P N|Pangon, L|Lucas, M C|Allam, A H|Currey, N|Al-Sohaily, S|Giry-Laterriere, M|Warusavitarne, J|Timpson, P|Kohonen-Corish, M R J
PMID: 29035389
Journal: J Mol Graph Model. 2018 Mar;80:48-51.
Title: Transcriptome-wide identification and competitive disruption of sacum-binding partners in human colorectal cancer.
Author: Zhang, Yinguang|Zhang, Yongwang|Zhang, Yuxiang
PMID: 29328992
Journal: Oncotarget. 2017 Dec 8;9(5):5979-5992.
Title: Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action.
Author: Kim, Mi Seon|Yoo, Byong Chul|Yang, Woo Seok|Han, Sang Yun|Jeong, Deok|Song, Jun Min|Kim, Kyung Hee|Aravinthan, Adithan|Kim, Ji Hye|Kim, Jong-Hoon|Kim, Seung Cheol|Cho, Jae Youl
PMID: 29464048
Journal: Acta Biochim Biophys Sin (Shanghai). 2018 Apr 1;50(4):355-361.
Title: BRAF and EGFR inhibitors synergize to increase cytotoxic effects and decrease stem cell capacities in BRAF(V600E)-mutant colorectal cancer cells.
Author: Wu, Zhenhua|Huang, Mingzhu|Gong, Yiwei|Lin, Chen|Guo, Weijian
PMID: 29534162
Journal: Cancer Biomark. 2018;22(1):89-99.
Title: Potential biomarkers for the early diagnosis of colorectal adenocarcinoma - transcriptomic analysis of four clinical stages.
Author: Janikowska, Grazyna|Janikowski, Tomasz|Pyka-Pajak, Alina|Mazurek, Urszula|Janikowski, Marcin|Gonciarz, Maciej|Lorenc, Zbigniew
PMID: 29562499
Journal: J Agric Food Chem. 2018 May 23;66(20):5139-5148.
Title: Andrographolide Antagonizes TNF-alpha-Induced IL-8 via Inhibition of NADPH Oxidase/ROS/NF-kappaB and Src/MAPKs/AP-1 Axis in Human Colorectal Cancer HCT116 Cells.
Author: Yuan, Miaomiao|Meng, Wei|Liao, Wenzhen|Lian, Sen
PMID: 29672044
Journal: Int J Mol Med. 2018 Jul;42(1):368-380.
Title: Inflammatory genes are novel prognostic biomarkers for colorectal cancer.
Author: Jiang, Hao|Dong, Li|Gong, Fangyan|Gu, Yuping|Zhang, Henghun|Fan, Dong|Sun, Zhiguo
PMID: 29693170
Journal: Oncotarget. 2018 Apr 3;9(25):17443-17454.
Title: IL-6 influences the polarization of macrophages and the formation and growth of colorectal tumor.
Author: Chen, Lechuang|Wang, Shuren|Wang, Yu|Zhang, Weina|Ma, Kai|Hu, Chenfei|Zhu, Hongxia|Liang, Shufang|Liu, Mei|Xu, Ningzhi
PMID: 29707119
Journal: Cell Death Dis. 2018 Apr 1;9(4):438.
Title: MicroRNA-181a promotes angiogenesis in colorectal cancer by targeting SRCIN1 to promote the SRC/VEGF signaling pathway.
Author: Sun, Wu|Wang, Xiaojun|Li, Jialu|You, Chaoying|Lu, Pan|Feng, Huijin|Kong, Yan|Zhang, Haiyang|Liu, Yanqing|Jiao, Ruihua|Chen, Xi|Ba, Yi
PMID: 29739921
Journal: Sci Rep. 2018 May 8;8(1):7238.
Title: Molecular targets of Chinese herbs: a clinical study of metastatic colorectal cancer based on network pharmacology.
Author: Zhu, Hongxu|Hao, Jian|Niu, Yangyang|Liu, Dan|Chen, Dan|Wu, Xiongzhi
PMID: 29740162
Journal: Oncotarget. 2018 Apr 17;9(29):20426-20438.
Title: Hotspot KRAS exon 2 mutations in CD166 positive colorectal cancer and colorectal adenoma cells.
Author: Wong, Hung Lai|Ng, Lawrence Po Wah|Koh, Su Pin|Chan, Lawrence Wing Chi|Wong, Evelyn Yin Kwan|Xue, Vivian Weiwen|Tsang, Hin Fung Andy|Chan, Amanda Kit Ching|Chiu, Ka Yue|Cheuk, Wah|Wong, Sze Chuen Cesar
PMID: 29755662
Journal: Onco Targets Ther. 2018 May 15;11:2843-2852.
Title: NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation.
Author: Li, Ting|Sun, Ruochuan|Lu, Mingdian|Chang, Jiacong|Meng, Xiangling|Wu, Huo
PMID: 29844682
Journal: Cell Death Discov. 2018 May 23;4:61.
Title: Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation.
Author: Fu, Yang|Yang, Ge|Xue, Peipei|Guo, Luwei|Yin, Yuhan|Ye, Zhiqiang|Peng, Sanfei|Qin, Yanru|Duan, Qiuhong|Zhu, Feng
PMID: 29844931
Journal: Genes Cells. 2018 Jul 2.
Title: MicroRNA-137-mediated Src oncogenic signaling promotes cancer progression.
Author: Kokuda, Rie|Watanabe, Risayo|Okuzaki, Daisuke|Akamatsu, Hiroki|Oneyama, Chitose
PMID: 29962093
Journal: Mol Cell Endocrinol. 2018 Jul 21. pii: S0303-7207(18)30221-1.
Title: Potential therapeutic targets for growth arrest of colorectal cancer cells exposed to PTHrP.
Author: Martin, Maria Julia|Gigola, Graciela|Zwenger, Ariel|Carriquiriborde, Martin|Gentil, Florencia|Gentili, Claudia
PMID: 30009852
Journal: Sci Rep. 2018 Jul 26;8(1):11285.
Title: Annexin A2 overexpression associates with colorectal cancer invasiveness and TGF-ss induced epithelial mesenchymal transition via Src/ANXA2/STAT3.
Author: Rocha, Murilo R|Barcellos-de-Souza, Pedro|Sousa-Squiavinato, Annie Cristhine M|Fernandes, Priscila V|de Oliveira, Ivanir M|Boroni, Mariana|Morgado-Diaz, Jose A
PMID: 30050103
Journal: Anticancer Res. 2018 Aug;38(8):4667-4676.
Title: Investigation into Enhancing Capecitabine Efficacy in Colorectal Cancer by Inhibiting Focal Adhesion Kinase Signaling.
Author: Sim, Jae Jun|Park, Min Hee|Baek, Jeong-Heum|Lee, Haejun|Jeong, Keun-Yeong|Kim, Hwan Mook
PMID: 30061234
Journal: Tumour Biol. 2018 Aug;40(8):1010428318794217.
Title: TP53-dependence on the effect of doxorubicin and Src inhibitor combination therapy.
Author: Lee, Yun Sun|Choi, Ji-Yoon|Lee, Jeeyun|Shim, Da Mi|Kim, Jaesoo|Park, Woong-Yang|Nam, Do-Hyun|Seo, Sung Wook
PMID: 30124118
Journal: Sci Rep. 2018 Aug 20;8(1):12424.
Title: The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway.
Author: Ta, Ngoc Ly|Chakrabandhu, Krittalak|Huault, Sebastien|Hueber, Anne-Odile
PMID: 30127519
Journal: Cell Death Dis. 2018 Aug 29;9(9):877.
Title: Novel beta-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer.
Author: Kim, Su Jin|Noh, Tae Hwan|Son, Sujin|Kim, Do Hyun|Kim, Wooseong|Lee, Yunna|Choo, Jieun|Heo, Gwangbeom|Kim, Min Jae|Chung, Hae Young|Jung, Yunjin|Jung, Jee Hyung|Moon, Hyung Ryong|Im, Eunok
PMID: 30158525
Journal: Histopathology. 2018 Aug 30.
Title: Associations Among Histologic Characteristics and Patient Outcomes in Colorectal Carcinoma with a Mucinous Component.
Author: Gonzalez, Raul S|Cates, Justin M M|Washington, Kay
PMID: 30160323
Journal: J Drug Target. 2018 Sep 12:1-19.
Title: The roles and mechanisms of G3BP1 in tumour promotion.
Author: Zhang, Cong-Hui|Wang, Jun-Xia|Cai, Mei-Lian|Shao, Rongguang|Liu, Hong|Zhao, Wu-Li
PMID: 30207743
Journal: Cancer Biol Ther. 2018 Oct 25:1-9.
Title: RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-kappaB pathway.
Author: Lu, Peifen|Chen, Junjun|Yan, Lihong|Yang, Lijun|Zhang, Litao|Dai, Jie|Hao, Zixuan|Bai, Tao|Xi, Yanfeng|Li, Yahui|Kang, Zhiming|Xv, Jun|Sun, Gongqin|Yang, Tao
PMID: 30359168
Journal: World J Gastrointest Oncol. 2018 Oct 15;10(10):290-292.
Title: Inhibiting focal adhesion kinase: A potential target for enhancing therapeutic efficacy in colorectal cancer therapy.
Author: Jeong, Keun-Yeong
PMID: 30364839