Literatures

Primary Site >> Liver Cancer

Gene >> SQSTM1

1.
Journal:	Anticancer Res. 1989 May-Jun;9(3):715-21.
Title:	Expression of ras and myc oncogenes in human hepatocellular carcinoma and non-neoplastic liver tissues.
Author:	Tiniakos, D\|Spandidos, D A\|Kakkanas, A\|Pintzas, A\|Pollice, L\|Tiniakos, G
PMID:	2548435

2.
Journal:	Hepatogastroenterology. 1993 Feb;40(1):37-40.
Title:	Expression of ras and c-myc oncoproteins and hepatitis B surface antigen in human liver disease.
Author:	Tiniakos, D\|Spandidos, D A\|Yiagnisis, M\|Tiniakos, G
PMID:	8462926

3.
Journal:	Am J Pathol. 1999 Jun;154(6):1701-10.
Title:	Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent.
Author:	Stumptner, C\|Heid, H\|Fuchsbichler, A\|Hauser, H\|Mischinger, H J\|Zatloukal, K\|Denk, H
PMID:	10362795

4.
Journal:	Verh Dtsch Ges Pathol. 1999;83:254-9.
Title:	Identification of p62, a phosphotyrosine independent ligand of p56lck kinase, as a major component of intracytoplasmic hyaline bodies in hepatocellular carcinoma.
Author:	Stumptner, C\|Heid, H\|Zatloukal, K\|Fuchsbichler, A\|Hauser, H\|Denk, H
PMID:	10714219

5.
Journal:	Virchows Arch. 2001 Jun;438(6):567-73.
Title:	Expression of a glypican-related 62-kDa antigen is decreased in hepatocellular carcinoma in correspondence to the grade of tumor differentiation.
Author:	Lage, H\|Kellner, U\|Tannapfel, A\|Dietel, M
PMID:	11469688

6.
Journal:	Clin Exp Immunol. 2001 Jul;125(1):3-9.
Title:	De-novo humoral immune responses to cancer-associated autoantigens during transition from chronic liver disease to hepatocellular carcinoma.
Author:	Zhang, J Y\|Zhu, W\|Imai, H\|Kiyosawa, K\|Chan, E K\|Tan, E M
PMID:	11472419

7.
Journal:	Am J Pathol. 2001 Sep;159(3):945-53.
Title:	Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis.
Author:	Lu, M\|Nakamura, R M\|Dent, E D\|Zhang, J Y\|Nielsen, F C\|Christiansen, J\|Chan, E K\|Tan, E M
PMID:	11549587

8.
Journal:	Am J Pathol. 2002 Jan;160(1):255-63.
Title:	p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases.
Author:	Zatloukal, Kurt\|Stumptner, Cornelia\|Fuchsbichler, Andrea\|Heid, Hans\|Schnoelzer, Martina\|Kenner, Lukas\|Kleinert, Reinhold\|Prinz, Marco\|Aguzzi, Adriano\|Denk, Helmut
PMID:	11786419

9.
Journal:	Oncogene. 2002 Jul 25;21(32):5006-15.
Title:	Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Author:	Soo Hoo, Linda\|Zhang, Jianying Y\|Chan, Edward K L
PMID:	12118381

10.
Journal:	Autoimmun Rev. 2002 May;1(3):146-53.
Title:	Autoantibodies to IGF-II mRNA binding protein p62 and overexpression of p62 in human hepatocellular carcinoma.
Author:	Zhang, Jianying\|Chan, Edward K L
PMID:	12849008

11.
Journal:	Clin Cancer Res. 2003 Nov 1;9(14):5120-6.
Title:	Recursive partitioning as an approach to selection of immune markers for tumor diagnosis.
Author:	Koziol, James A\|Zhang, Jian-Ying\|Casiano, Carlos A\|Peng, Xuan-Xian\|Shi, Fu-Dong\|Feng, Anne C\|Chan, Edward K L\|Tan, Eng M
PMID:	14613989

12.
Journal:	Zhonghua Bing Li Xue Za Zhi. 2003 Aug;32(4):329-32.
Title:	[Significance of a novel fetal RNA-binding protein p62 expression in hepatocellular carcinoma].
Author:	Qian, Hong-liu\|Chen, Shou-hui\|Peng, Xuan-xian
PMID:	14514377

13.
Journal:	Oncogene. 2003 Sep 25;22(41):6319-31.
Title:	Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas.
Author:	Motiwala, Tasneem\|Ghoshal, Kalpana\|Das, Anindita\|Majumder, Sarmila\|Weichenhan, Dieter\|Wu, Yue-Zhong\|Holman, Kristen\|James, S Jill\|Jacob, Samson T\|Plass, Christoph
PMID:	14508512

14.
Journal:	Cancer Epidemiol Biomarkers Prev. 2003 Feb;12(2):136-43.
Title:	Enhancement of antibody detection in cancer using panel of recombinant tumor-associated antigens.
Author:	Zhang, Jian-Ying\|Casiano, Carlos A\|Peng, Xuan-Xian\|Koziol, James A\|Chan, Edward K L\|Tan, Eng M
PMID:	12582023

15.
Journal:	Int J Biochem Cell Biol. 2005 Mar;37(3):616-27.
Title:	Effect of all-trans-retinoic acid on mRNA binding protein p62 in human gastric cancer cells.
Author:	Ping, Shi\|Wang, Sanying\|Zhang, Jianying\|Peng, Xuanxian
PMID:	15618018

16.
Journal:	World J Gastroenterol. 2005 Mar 28;11(12):1788-92.
Title:	p62 Expression in primary carcinomas of the digestive system.
Author:	Qian, Hong-Liu\|Peng, Xuan-Xian\|Chen, Shou-Hui\|Ye, Hui-Ming\|Qiu, Jing-Hua
PMID:	15793865

17.
Journal:	Clin Immunol. 2005 Aug;116(2):118-23.
Title:	The diversity expression of p62 in digestive system cancers.
Author:	Su, Youxin\|Qian, Hongliu\|Zhang, Jianying\|Wang, Sanyin\|Shi, Ping\|Peng, Xuanxian
PMID:	15886058

18.
Journal:	J Pathol. 2006 Apr;208(5):653-61.
Title:	Are the Mallory bodies and intracellular hyaline bodies in neoplastic and non-neoplastic hepatocytes related?
Author:	Denk, H\|Stumptner, C\|Fuchsbichler, A\|Muller, T\|Farr, Gh\|Muller, W\|Terracciano, L\|Zatloukal, K
PMID:	16477590

19.
Journal:	J Hepatol. 2007 Jan;46(1):107-14.
Title:	Antibody detection using tumor-associated antigen mini-array in immunodiagnosing human hepatocellular carcinoma.
Author:	Zhang, Jian-Ying\|Megliorino, Roxanne\|Peng, Xuan-Xian\|Tan, Eng M\|Chen, Yao\|Chan, Edward K L
PMID:	17067715

20.
Journal:	Hepatology. 2007 Sep;46(3):851-60.
Title:	In vitro production of Mallory bodies and intracellular hyaline bodies: the central role of sequestosome 1/p62.
Author:	Stumptner, Conny\|Fuchsbichler, Andrea\|Zatloukal, Kurt\|Denk, Helmut
PMID:	17685470

21.
Journal:	Hepatology. 2010 Apr;51(4):1244-54.
Title:	Serotonin promotes tumor growth in human hepatocellular cancer.
Author:	Soll, Christopher\|Jang, Jae Hwi\|Riener, Marc-Oliver\|Moritz, Wolfgang\|Wild, Peter Johannes\|Graf, Rolf\|Clavien, Pierre-Alain
PMID:	20099302

22.
Journal:	Nat Cell Biol. 2010 Mar;12(3):213-23.
Title:	The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Author:	Komatsu, Masaaki\|Kurokawa, Hirofumi\|Waguri, Satoshi\|Taguchi, Keiko\|Kobayashi, Akira\|Ichimura, Yoshinobu\|Sou, Yu-Shin\|Ueno, Izumi\|Sakamoto, Ayako\|Tong, Kit I\|Kim, Mihee\|Nishito, Yasumasa\|Iemura, Shun-ichiro\|Natsume, Tohru\|Ueno, Takashi\|Kominami, Eiki\|Motoh
PMID:	20173742

23.
Journal:	Wei Sheng Wu Xue Bao. 2010 Dec;50(12):1651-6.
Title:	[Infection with hepatitis B virus enhances basal autophagy].
Author:	Wang, Juan\|Shi, Yingdi\|Yang, Huaiyi
PMID:	21365919

24.
Journal:	J Hepatol. 2011 May;54(5):994-1001.
Title:	Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype.
Author:	Tybl, Elisabeth\|Shi, Fu-Dong\|Kessler, Sonja M\|Tierling, Sascha\|Walter, Jorn\|Bohle, Rainer M\|Wieland, Stefan\|Zhang, Jianying\|Tan, Eng M\|Kiemer, Alexandra K
PMID:	21145819

25.
Journal:	Biochem J. 2011 Nov 15;440(1):63-71.
Title:	Induction of an incomplete autophagic response by cancer-preventive geranylgeranoic acid (GGA) in a human hepatoma-derived cell line.
Author:	Okamoto, Kyoko\|Sakimoto, Yoko\|Imai, Katsuyuki\|Senoo, Haruki\|Shidoji, Yoshihiro
PMID:	21787360

26.
Journal:	Gastroenterology. 2011 Sep;141(3):1080-1090.e1-7.
Title:	Cross beta-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.
Author:	Mahajan, Vineet\|Klingstedt, Therese\|Simon, Rozalyn\|Nilsson, K Peter R\|Thueringer, Andrea\|Kashofer, Karl\|Haybaeck, Johannes\|Denk, Helmut\|Abuja, Peter M\|Zatloukal, Kurt
PMID:	21699779

27.
Journal:	Autophagy. 2011 Sep;7(9):1088-90. Epub 2011 Sep 1.
Title:	Potential role of p62 in tumor development.
Author:	Komatsu, Masaaki
PMID:	21617386

28.
Journal:	J Cell Biol. 2011 Apr 18;193(2):275-84.
Title:	Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.
Author:	Inami, Yoshihiro\|Waguri, Satoshi\|Sakamoto, Ayako\|Kouno, Tsuguka\|Nakada, Kazuto\|Hino, Okio\|Watanabe, Sumio\|Ando, Jin\|Iwadate, Manabu\|Yamamoto, Masayuki\|Lee, Myung-Shik\|Tanaka, Keiji\|Komatsu, Masaaki
PMID:	21482715

29.
Journal:	J Proteome Res. 2011 Aug 5;10(8):3418-28.
Title:	iTRAQ-2DLC-ESI-MS/MS based identification of a new set of immunohistochemical biomarkers for classification of dysplastic nodules and small hepatocellular carcinoma.
Author:	Jin, Guang-Zhi\|Li, Yan\|Cong, Wen-Ming\|Yu, Hua\|Dong, Hui\|Shu, Hong\|Liu, Xiao-Hui\|Yan, Guo-Quan\|Zhang, Lei\|Zhang, Yang\|Kang, Xiao-Nan\|Guo, Kun\|Wang, Zhe-Dong\|Yang, Peng-Yuan\|Liu, Yin-Kun
PMID:	21631109

30.
Journal:	Cancer Sci. 2012 Apr;103(4):760-6.
Title:	Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma.
Author:	Inoue, Daisuke\|Suzuki, Takashi\|Mitsuishi, Yoichiro\|Miki, Yasuhiro\|Suzuki, Satoshi\|Sugawara, Shunichi\|Watanabe, Mika\|Sakurada, Akira\|Endo, Chiaki\|Uruno, Akira\|Sasano, Hironobu\|Nakagawa, Takayuki\|Satoh, Kennichi\|Tanaka, Nobuyuki\|Kubo, Hiroshi\|Motohashi, Hoz
PMID:	22320446

31.
Journal:	J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:10-4.
Title:	Obesity, autophagy and the pathogenesis of liver and pancreatic cancers.
Author:	Aghajan, Mariam\|Li, Ning\|Karin, Michael
PMID:	22320909

32.
Journal:	Int J Oncol. 2012 Jun;40(6):2049-57.
Title:	Emerging role of autophagy during ischemia-hypoxia and reperfusion in hepatocellular carcinoma.
Author:	Du, Hailei\|Yang, Weiping\|Chen, Lin\|Shen, Baiyong\|Peng, Chenghong\|Li, Hongwei\|Ann, David K\|Yen, Yun\|Qiu, Weihua
PMID:	22469951

33.
Journal:	Cancer. 2012 Nov 15;118(22):5560-71.
Title:	Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.
Author:	Hui, Bo\|Shi, Ying-Hong\|Ding, Zhen-Bin\|Zhou, Jian\|Gu, Cheng-Yu\|Peng, Yuan-Fei\|Yang, Hua\|Liu, Wei-Ren\|Shi, Guo-Ming\|Fan, Jia
PMID:	22517429

34.
Journal:	Autophagy. 2012 Dec;8(12):1859-61.
Title:	Autophagic flux, supported by toll-like receptor 2 activity, defends against the carcinogenesis of hepatocellular carcinoma.
Author:	Lin, Heng\|Hua, Fang\|Hu, Zhuo-Wei
PMID:	22996042

35.
Journal:	Autophagy. 2013 Apr;9(4):619-21.
Title:	Targeting NFKB by autophagy to polarize hepatoma-associated macrophage differentiation.
Author:	Chang, Chih-Peng\|Su, Yu-Chi\|Lee, Pei-Huan\|Lei, Huan-Yao
PMID:	23360732

36.
Journal:	Asian Pac J Cancer Prev. 2013;14(10):5849-54.
Title:	Blocking Bcl-2 leads to autophagy activation and cell death of the HEPG2 liver cancer cell line.
Author:	Du, Peng\|Cao, Hua\|Wu, Hao-Rong\|Zhu, Bao-Song\|Wang, Hao-Wei\|Gu, Chun-Wei\|Xing, Chun-Gen\|Chen, Wei
PMID:	24289588

37.
Journal:	Int J Mol Sci. 2013 Nov 25;14(12):23212-30.
Title:	Blocking autophagic flux enhances matrine-induced apoptosis in human hepatoma cells.
Author:	Wang, Li\|Gao, Chun\|Yao, Shukun\|Xie, Bushan
PMID:	24287900

38.
Journal:	PLoS One. 2013 Oct 2;8(10):e74130.
Title:	Antioxidant N-acetylcysteine attenuates hepatocarcinogenesis by inhibiting ROS/ER stress in TLR2 deficient mouse.
Author:	Lin, Heng\|Liu, Xiao-bo\|Yu, Jiao-jiao\|Hua, Fang\|Hu, Zhuo-wei
PMID:	24098333

39.
Journal:	Cancer Lett. 2013 Sep 1;337(2):254-65.
Title:	Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models.
Author:	Adiseshaiah, Pavan P\|Clogston, Jeffrey D\|McLeland, Christopher B\|Rodriguez, Jamie\|Potter, Timothy M\|Neun, Barry W\|Skoczen, Sarah L\|Shanmugavelandy, Sriram S\|Kester, Mark\|Stern, Stephan T\|McNeil, Scott E
PMID:	23664889

40.
Journal:	Cell Death Dis. 2013 May 2;4:e618.
Title:	Involvement of PPARgamma in the antitumoral action of cannabinoids on hepatocellular carcinoma.
Author:	Vara, D\|Morell, C\|Rodriguez-Henche, N\|Diaz-Laviada, I
PMID:	23640460

41.
Journal:	BMC Cancer. 2013 Mar 27;13:161.
Title:	A novel panel of biomarkers in distinction of small well-differentiated HCC from dysplastic nodules and outcome values.
Author:	Jin, Guang-Zhi\|Dong, Hui\|Yu, Wen-Long\|Li, Yan\|Lu, Xin-Yuan\|Yu, Hua\|Xian, Zhi-Hong\|Dong, Wei\|Liu, Yin-Kun\|Cong, Wen-Ming\|Wu, Meng-Chao
PMID:	23537217

42.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G328-36.
Title:	IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling.
Author:	Kessler, Sonja M\|Pokorny, Juliane\|Zimmer, Vincent\|Laggai, Stephan\|Lammert, Frank\|Bohle, Rainer M\|Kiemer, Alexandra K
PMID:	23257922

43.
Journal:	Cell Death Differ. 2013 Mar;20(3):515-23.
Title:	TLR2-dependent selective autophagy regulates NF-kappaB lysosomal degradation in hepatoma-derived M2 macrophage differentiation.
Author:	Chang, C-P\|Su, Y-C\|Hu, C-W\|Lei, H-Y
PMID:	23175187

44.
Journal:	Autophagy. 2014;10(12):2385-6.
Title:	Calcium channel blockers as potential therapeutics for obesity-associated autophagy defects and fatty liver pathologies.
Author:	Park, Hwan-Woo\|Lee, Jun Hee
PMID:	25484079

45.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2014 Jul;45(4):587-90.
Title:	[Feverfew lactone induces autophagic death of hepatocellular carcinoma SMMC 7721 cells].
Author:	Liu, Zhan-Pei\|Li, Yan-Yan\|Gao, Bo\|Li, Jun\|Gao, Jun-Ping\|Lin, Ping
PMID:	25286681

46.
Journal:	Acta Neuropathol Commun. 2014 May 3;2:50.
Title:	Phosphorylation of serine 349 of p62 in Alzheimer's disease brain.
Author:	Tanji, Kunikazu\|Miki, Yasuo\|Ozaki, Taku\|Maruyama, Atsushi\|Yoshida, Hidemi\|Mimura, Junsei\|Matsumiya, Tomoh\|Mori, Fumiaki\|Imaizumi, Tadaatsu\|Itoh, Ken\|Kakita, Akiyoshi\|Takahashi, Hitoshi\|Wakabayashi, Koichi
PMID:	24886973

47.
Journal:	Exp Mol Pathol. 2014 Apr;96(2):149-54.
Title:	Impaired autophagy response in human hepatocellular carcinoma.
Author:	Bao, Lili\|Chandra, Partha K\|Moroz, Krzysztof\|Zhang, Xuchen\|Thung, Swan N\|Wu, Tong\|Dash, Srikanta
PMID:	24369267

48.
Journal:	Autophagy. 2014 Jan;10(1):111-22.
Title:	Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma.
Author:	Liu, Xiao-Wen\|Cai, Tian-Yu\|Zhu, Hong\|Cao, Ji\|Su, Yi\|Hu, Yong-Zhou\|He, Qiao-Jun\|Yang, Bo
PMID:	24220190

49.
Journal:	Autophagy. 2014 Mar;10(3):416-30.
Title:	Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation.
Author:	Liu, Bo\|Fang, Mengdie\|Hu, Ye\|Huang, Baoshan\|Li, Ning\|Chang, Chunmei\|Huang, Rui\|Xu, Xiao\|Yang, Zhenggang\|Chen, Zhi\|Liu, Wei
PMID:	24401568

50.
Journal:	Int J Mol Sci. 2015 Oct 27;16(10):25744-58.
Title:	JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1.
Author:	Yang, Jiong\|Yao, Shukun
PMID:	26516844

51.
Journal:	Cell Death Dis. 2015 Nov 19;6:e1980.
Title:	Hepatitis B virus stimulates G6PD expression through HBx-mediated Nrf2 activation.
Author:	Liu, B\|Fang, M\|He, Z\|Cui, D\|Jia, S\|Lin, X\|Xu, X\|Zhou, T\|Liu, W
PMID:	26583321

52.
Journal:	Cell Death Dis. 2015 Oct 1;6:e1894.
Title:	IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.
Author:	Kessler, S M\|Laggai, S\|Barghash, A\|Schultheiss, C S\|Lederer, E\|Artl, M\|Helms, V\|Haybaeck, J\|Kiemer, A K
PMID:	26426686

53.
Journal:	Virchows Arch. 2015 Aug;467(2):237-45.
Title:	Hepatoid carcinoma of the pancreas with lymphoid stroma: first description of the clinical, morphological, immunohistochemical, and molecular characteristics of an unusual pancreatic carcinoma.
Author:	Vanoli, Alessandro\|Argenti, Francesca\|Vinci, Alessio\|La Rosa, Stefano\|Viglio, Alessandra\|Riboni, Roberta\|Necchi, Vittorio\|Pugliese, Luigi\|Sessa, Fausto\|Pietrabissa, Andrea\|Paulli, Marco
PMID:	25989715

54.
Journal:	Mol Med Rep. 2015 Aug;12(2):1677-84.
Title:	Sann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways.
Author:	Chuang, Wan-Ling\|Su, Chin-Cheng\|Lin, Ping-Yi\|Lin, Chi-Chen\|Chen, Yao-Li
PMID:	25847489

55.
Journal:	Oncotarget. 2015 Apr 20;6(11):9420-33.
Title:	PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis.
Author:	Zhang, Wenjie\|Hou, Jiajie\|Wang, Xiaochen\|Jiang, Runqiu\|Yin, Yin\|Ji, Jie\|Deng, Lei\|Huang, Xingxu\|Wang, Ke\|Sun, Beicheng
PMID:	25826083

56.
Journal:	Mol Carcinog. 2015 Oct;54(10):1194-204.
Title:	Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients.
Author:	Jiang, Xianhan\|Zhong, Weide\|Huang, Hai\|He, Huichan\|Jiang, Funeng\|Chen, Yanru\|Yue, Fei\|Zou, Jing\|Li, Xun\|He, Yongzhong\|You, Pan\|Yang, Weiqiang\|Lai, Yiming\|Wang, Fen\|Liu, Leyuan
PMID:	25043940

57.
Journal:	Sci Rep. 2016 Nov 15;6:37052.
Title:	Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways.
Author:	Yan, Yumei\|Jiang, Ke\|Liu, Peng\|Zhang, Xianbin\|Dong, Xin\|Gao, Jingchun\|Liu, Quentin\|Barr, Martin P\|Zhang, Quan\|Hou, Xiukun\|Meng, Songshu\|Gong, Peng
PMID:	27845389

58.
Journal:	Case Reports Hepatol. 2016;2016:2032714.
Title:	Hepatocellular Carcinoma with Prominent Intracytoplasmic Inclusions: A Report of Two Cases.
Author:	Chelliah, Adeline R\|Radhi, Jasim M
PMID:	27818805

59.
Journal:	Cancer Cell. 2016 Oct 10;30(4):595-609.
Title:	p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer.
Author:	Duran, Angeles\|Hernandez, Eloy D\|Reina-Campos, Miguel\|Castilla, Elias A\|Subramaniam, Shankar\|Raghunandan, Sindhu\|Roberts, Lewis R\|Kisseleva, Tatiana\|Karin, Michael\|Diaz-Meco, Maria T\|Moscat, Jorge
PMID:	27728806

60.
Journal:	Cancer Cell. 2016 Oct 10;30(4):509-510.
Title:	p62 in Liver Disease: Good Guy or Bad Guy?
Author:	Hu, Zexi\|Zender, Lars
PMID:	27728799

61.
Journal:	Autophagy. 2016 Dec;12(12):2271-2285.
Title:	Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy.
Author:	Chi, Hsiang-Cheng\|Chen, Shen-Liang\|Tsai, Chung-Ying\|Chuang, Wen-Yu\|Huang, Ya-Hui\|Tsai, Ming-Ming\|Wu, Sheng-Ming\|Sun, Cheng-Pu\|Yeh, Chau-Ting\|Lin, Kwang-Huei
PMID:	27653365

62.
Journal:	PLoS One. 2016 Aug 15;11(8):e0161083.
Title:	p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies.
Author:	Lahiri, Pooja\|Schmidt, Volker\|Smole, Claudia\|Kufferath, Iris\|Denk, Helmut\|Strnad, Pavel\|Rulicke, Thomas\|Frohlich, Leopold F\|Zatloukal, Kurt
PMID:	27526095

63.
Journal:	PLoS One. 2016 Aug 15;11(8):e0161025.
Title:	A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells.
Author:	Cao, Lili\|Zhang, Lijun\|Zhao, Xiang\|Zhang, Ye
PMID:	27525972

64.
Journal:	FEBS Lett. 2016 Aug;590(15):2375-97.
Title:	p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.
Author:	Taniguchi, Koji\|Yamachika, Shinichiro\|He, Feng\|Karin, Michael
PMID:	27404485

65.
Journal:	Oncotarget. 2016 Aug 2;7(31):49743-49750.
Title:	Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma.
Author:	Barghash, Ahmad\|Golob-Schwarzl, Nicole\|Helms, Volkhard\|Haybaeck, Johannes\|Kessler, Sonja M
PMID:	27391348

66.
Journal:	Int J Mol Sci. 2016 Jun 28;17(7). pii: ijms17071015.
Title:	A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells.
Author:	Chen, Yonglin\|Shi, Songshan\|Wang, Huijun\|Li, Ning\|Su, Juan\|Chou, Guixin\|Wang, Shunchun
PMID:	27367669

67.
Journal:	Nat Commun. 2016 Jun 27;7:12030.
Title:	p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.
Author:	Saito, Tetsuya\|Ichimura, Yoshinobu\|Taguchi, Keiko\|Suzuki, Takafumi\|Mizushima, Tsunehiro\|Takagi, Kenji\|Hirose, Yuki\|Nagahashi, Masayuki\|Iso, Tetsuro\|Fukutomi, Toshiaki\|Ohishi, Maki\|Endo, Keiko\|Uemura, Takefumi\|Nishito, Yasumasa\|Okuda, Shujiro\|Obata, Miki\|K
PMID:	27345495

68.
Journal:	J Hepatobiliary Pancreat Sci. 2016 Aug;23(8):467-71.
Title:	Accumulation of phosphorylated p62 is associated with NF-E2-related factor 2 activation in hepatocellular carcinoma.
Author:	Shimizu, Takayuki\|Inoue, Ken-Ichi\|Hachiya, Hiroyuki\|Shibuya, Norisuke\|Aoki, Taku\|Kubota, Keiichi
PMID:	27246794

69.
Journal:	J Cachexia Sarcopenia Muscle. 2016 Dec;7(5):555-566.
Title:	Megestrol acetate improves cardiac function in a model of cancer cachexia-induced cardiomyopathy by autophagic modulation.
Author:	Musolino, Vincenzo\|Palus, Sandra\|Tschirner, Anika\|Drescher, Cathleen\|Gliozzi, Micaela\|Carresi, Cristina\|Vitale, Cristiana\|Muscoli, Carolina\|Doehner, Wolfram\|von Haehling, Stephan\|Anker, Stefan D\|Mollace, Vincenzo\|Springer, Jochen
PMID:	27239419

70.
Journal:	Cancer Cell. 2016 Jun 13;29(6):935-948.
Title:	p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.
Author:	Umemura, Atsushi\|He, Feng\|Taniguchi, Koji\|Nakagawa, Hayato\|Yamachika, Shinichiro\|Font-Burgada, Joan\|Zhong, Zhenyu\|Subramaniam, Shankar\|Raghunandan, Sindhu\|Duran, Angeles\|Linares, Juan F\|Reina-Campos, Miguel\|Umemura, Shiori\|Valasek, Mark A\|Seki, Ekihiro\|Ya
PMID:	27211490

71.
Journal:	J Biol Chem. 2016 Sep 9;291(37):19299-311.
Title:	Mycotoxin Patulin Suppresses Innate Immune Responses by Mitochondrial Dysfunction and p62/Sequestosome-1-dependent Mitophagy.
Author:	Tsai, Wan-Ting\|Lo, Yin-Chiu\|Wu, Ming-Sian\|Li, Chia-Yang\|Kuo, Yi-Ping\|Lai, Yi-Hui\|Tsai, Yu\|Chen, Kai-Chieh\|Chuang, Tsung-Hsien\|Yao, Chun-Hsu\|Lee, Jinq-Chyi\|Hsu, Li-Chung\|Hsu, John T-A\|Yu, Guann-Yi
PMID:	27458013

72.
Journal:	Oncotarget. 2017 Sep 16;8(49):86227-86239.
Title:	Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling.
Author:	Han, Bing\|Yu, Yi-Qun\|Yang, Qi-Lian\|Shen, Chun-Ying\|Wang, Xiao-Juan
PMID:	29156790

73.
Journal:	Hepatology. 2017 Dec 18.
Title:	Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation.
Author:	Cho, Chun-Seok\|Park, Hwan-Woo\|Ho, Allison\|Semple, Ian A\|Kim, Boyoung\|Jang, Insook\|Park, Haeli\|Reilly, Shannon\|Saltiel, Alan R\|Lee, Jun Hee
PMID:	29251796

74.
Journal:	Oncotarget. 2017 Aug 1;8(54):91902-91913.
Title:	The autophagy marker LC3 strongly predicts immediate mortality after surgical resection for hepatocellular carcinoma.
Author:	Lin, Chih-Wen\|Lin, Chih-Che\|Lee, Po-Huang\|Lo, Gin-Ho\|Hsieh, Pei-Min\|Koh, Kah Wee\|Lee, Chih-Yuan\|Chen, Yao-Li\|Dai, Chia-Yen\|Huang, Jee-Fu\|Chuang, Wang-Long\|Chen, Yaw-Sen\|Yu, Ming-Lung
PMID:	29190884

75.
Journal:	Cell Death Dis. 2017 Oct 12;8(10):e3118.
Title:	The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.
Author:	Chen, Shuo\|Wu, Dan-Dan\|Sang, Xiu-Bo\|Wang, Li-Li\|Zong, Zhi-Hong\|Sun, Kai-Xuan\|Liu, Bo-Liang\|Zhao, Yang
PMID:	29022892

76.
Journal:	Cancer Lett. 2017 Dec 28;411:82-89.
Title:	Autophagy in the "inflammation-carcinogenesis" pathway of liver and HCC immunotherapy.
Author:	Yu, Sizhe\|Wang, Yu\|Jing, Li\|Claret, F X\|Li, Qing\|Tian, Tao\|Liang, Xuan\|Ruan, Zhiping\|Jiang, Lili\|Yao, Yu\|Nan, Kejun\|Lv, Yi\|Guo, Hui
PMID:	28987386

77.
Journal:	Ann Hepatol. 2017 Jul-Aug;16(4):607-618.
Title:	Hepatoprotective Effect of Curcumin on Hepatocellular Carcinoma Through Autophagic and Apoptic Pathways.
Author:	Elmansi, Ahmed\|El-Karef, Amro\|Shishtawy, Mamdouh\|Eissa, Laila
PMID:	28611265

78.
Journal:	Clin Transl Oncol. 2017 Dec;19(12):1507-1517.
Title:	Overexpression of dishevelled 2 is involved in tumor metastasis and is associated with poor prognosis in hepatocellular carcinoma.
Author:	Zhang, C\|Li, C\|Chen, X\|Zhou, Y\|Yin, B\|Ni, R\|Zhang, Y\|Liu, J
PMID:	28589433

79.
Journal:	Molecules. 2017 May 21;22(5). pii: molecules22050854.
Title:	A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating alpha-Tubulin Expression.
Author:	Chang, Wen-Tsan\|Liu, Wangta\|Chiu, Yi-Han\|Chen, Bing-Hung\|Chuang, Shih-Chang\|Chen, Yen-Chun\|Hsu, Yun-Tzh\|Lu, Mei-Jei\|Chiou, Shean-Jaw\|Chou, Chon-Kit\|Chiu, Chien-Chih
PMID:	28531143

80.
Journal:	Oncotarget. 2017 Jun 20;8(25):40019-40036.
Title:	Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma.
Author:	Chava, Srinivas\|Lee, Christine\|Aydin, Yucel\|Chandra, Partha K\|Dash, Asha\|Chedid, Milad\|Thung, Swan N\|Moroz, Krzysztof\|Wu, Tong\|Nayak, Nabeen C\|Dash, Srikanta
PMID:	28402954

81.
Journal:	Liver Int. 2017 Apr;37(4):600-610.
Title:	Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis.
Author:	Aigelsreiter, Ariane\|Neumann, Jens\|Pichler, Martin\|Halasz, Judith\|Zatloukal, Kurt\|Berghold, Andrea\|Douschan, Philipp\|Rainer, Florian\|Stauber, Rudolf\|Haybaeck, Johannes\|Denk, Helmut\|Lackner, Carolin
PMID:	27885796

82.
Journal:	Cancer Med. 2017 Oct;6(10):2357-2369.
Title:	Expression of P62 in hepatocellular carcinoma involving hepatitis B virus infection and aflatoxin B1 exposure.
Author:	Xiang, Xiao\|Qin, Hong-Gui\|You, Xue-Mei\|Wang, Yan-Yan\|Qi, Lu-Nan\|Ma, Liang\|Xiang, Bang-De\|Zhong, Jian-Hong\|Li, Le-Qun
PMID:	28941211

83.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Sep;49(5):689-693.
Title:	[Study on Autophagy and Apoptosis Induced by Amiodarone Combined with Glycyrrhetinic Acid in HepG2 Cells].
Author:	Wei, Qing-Zhu\|He, Li-Li\|Wang, Xiao-Yun\|Wu, Ling\|Gong, Lin-Hui\|Song, Xiang-Rong
PMID:	30378327

84.
Journal:	Hepatology. 2018 Oct 3.
Title:	DEAD Box Protein 5 Inhibits Liver Tumorigenesis by Stimulating Autophagy via Interaction with p62/SQSTM1.
Author:	Zhang, Hao\|Zhang, Yanqiu\|Zhu, Xiaoyun\|Chen, Chen\|Zhang, Chao\|Xia, Yuanzheng\|Zhao, Yucheng\|Andrisani, Ourania\|Kong, Lingyi
PMID:	30281815

85.
Journal:	Autophagy. 2018 Aug 21:1-21.
Title:	Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells.
Author:	Zhang, Zili\|Yao, Zhen\|Wang, Ling\|Ding, Hai\|Shao, Jiangjuan\|Chen, Anping\|Zhang, Feng\|Zheng, Shizhong
PMID:	30081711

86.
Journal:	Am J Pathol. 2018 Oct;188(10):2339-2355.
Title:	Chaperone-Mediated Autophagy Promotes Beclin1 Degradation in Persistently Infected Hepatitis C Virus Cell Culture.
Author:	Aydin, Yucel\|Stephens, Christopher M\|Chava, Srinivas\|Heidari, Zahra\|Panigrahi, Rajesh\|Williams, Donkita D\|Wiltz, Kylar\|Bell, Antoinette\|Wilson, Wallace\|Reiss, Krzysztof\|Dash, Srikanta
PMID:	30075149

87.
Journal:	Yakugaku Zasshi. 2018;138(8):1059-1065.
Title:	[Hit-to-Lead in Academia: Discovery of a Protein-Protein Interaction Inhibitor of Keap1-Nrf2].
Author:	Yasuda, Daisuke\|Obata, Rika\|Takahashi, Kyoko\|Ohe, Tomoyuki\|Mashino, Tadahiko
PMID:	30068847

88.
Journal:	Environ Toxicol. 2018 Sep;33(9):946-954.
Title:	Coronarin D induces apoptotic cell death through the JNK pathway in human hepatocellular carcinoma.
Author:	Lin, Hui-Wen\|Hsieh, Ming-Ju\|Yeh, Chao-Bin\|Hsueh, Kuan-Chun\|Hsieh, Yi-Hsien\|Yang, Shun-Fa
PMID:	29968959

89.
Journal:	Oncotarget. 2018 Jan 9;9(25):17368-17395.
Title:	An autophagy-related gene expression signature for survival prediction in multiple cohorts of hepatocellular carcinoma patients.
Author:	Lin, Peng\|He, Rong-Quan\|Dang, Yi-Wu\|Wen, Dong-Yue\|Ma, Jie\|He, Yun\|Chen, Gang\|Yang, Hong
PMID:	29707114

90.
Journal:	Biochem Biophys Res Commun. 2018 May 5;499(2):156-163.
Title:	Bigelovin, a sesquiterpene lactone, suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation in liver cancer.
Author:	Wang, Bei\|Zhou, Tan-Yang\|Nie, Chun-Hui\|Wan, Da-Long\|Zheng, Shu-Sen
PMID:	29548826

91.
Journal:	Eur J Pharmacol. 2018 Mar 15;823:58-64.
Title:	Aspirin induces Beclin-1-dependent autophagy of human hepatocellular carcinoma cell.
Author:	Huang, Zhenjun\|Fang, Weilun\|Liu, Weihua\|Wang, Li\|Liu, Bin\|Liu, Shiming\|Liu, Shaojun
PMID:	29408091

92.
Journal:	PLoS One. 2018 Jan 31;13(1):e0191805.
Title:	Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy.
Author:	Del Campo, Jose A\|Garcia-Valdecasas, Marta\|Gil-Gomez, Antonio\|Rojas, Angela\|Gallego, Paloma\|Ampuero, Javier\|Gallego-Duran, Rocio\|Pastor, Helena\|Grande, Lourdes\|Padillo, Francisco J\|Muntane, Jordi\|Romero-Gomez, Manuel
PMID:	29385181

93.
Journal:	Hepatology. 2018 Jul;68(1):141-154.
Title:	Hepatocellular carcinoma-related cyclin D1 is selectively regulated by autophagy degradation system.
Author:	Wu, Shan-Ying\|Lan, Sheng-Hui\|Wu, Shang-Rung\|Chiu, Yen-Chi\|Lin, Xi-Zhang\|Su, Ih-Jen\|Tsai, Ting-Fen\|Yen, Chia-Jui\|Lu, Tsung-Hsueh\|Liang, Fu-Wen\|Li, Chung-Yi\|Su, Huey-Jen\|Su, Chun-Li\|Liu, Hsiao-Sheng
PMID:	29328502

94.
Journal:	Sci Rep. 2018 Jan 8;8(1):106.
Title:	DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma.
Author:	Mizuno, Yuki\|Shimada, Shu\|Akiyama, Yoshimitsu\|Watanabe, Shuichi\|Aida, Tomomi\|Ogawa, Kosuke\|Ono, Hiroaki\|Mitsunori, Yusuke\|Ban, Daisuke\|Kudo, Atsushi\|Arii, Shigeki\|Yamaoka, Shoji\|Tanabe, Minoru\|Tanaka, Shinji
PMID:	29311600

95.
Journal:	Autophagy. 2018;14(4):671-684.
Title:	Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2).
Author:	Jiao, Lin\|Zhang, Hai-Liang\|Li, Dan-Dan\|Yang, Ke-Li\|Tang, Jun\|Li, Xuan\|Ji, Jiao\|Yu, Yan\|Wu, Rui-Yan\|Ravichandran, Senthilkumar\|Liu, Jian-Jun\|Feng, Gong-Kan\|Chen, Min-Shan\|Zeng, Yi-Xin\|Deng, Rong\|Zhu, Xiao-Feng
PMID:	28980855