Primary Site >> Colorectal Cancer

Gene >> SQSTM1

Journal: Cancer Res. 1985 Jun;45(6):2661-9.
Title: An isolated enriched organ-specific cancer neoantigen of human lung cancer for leukocyte adherence inhibition assays.
Author: Dubois, A E|Thomson, D M|Sutherland, M E|Scanzano, R
PMID: 3886136
Journal: Pathol Res Pract. 1990 Apr;186(2):205-11.
Title: Alteration and enhanced expression of the c-myc oncogene in human colorectal carcinomas.
Author: Matsumura, T|Dohi, K|Takanashi, A|Ito, H|Tahara, E
PMID: 2188234
Journal: J Pathol. 1990 Apr;160(4):287-93.
Title: Immunohistochemical demonstration of altered intracellular localization of the C-Myc oncogene product in human colorectal neoplasms.
Author: Williams, A R|Piris, J|Wyllie, A H
PMID: 2193134
Journal: Int J Colorectal Dis. 1993 Jul;8(2):103-5.
Title: Lack of prognostic value of immunoreactivity for p62 oncoprotein in colorectal carcinoma.
Author: Matsumoto, K|Yamamoto, J|Miura, T
PMID: 8409682
Journal: Surg Today. 1993;23(1):89-91.
Title: DNA ploidy, c-myc oncoprotein p62 and v-H-ras oncoprotein p21 in colorectal carcinoma.
Author: Teranishi, T|Matsumoto, K|Ishijima, N|Miura, T|Suzuki, H
PMID: 8461612
Journal: Clin Ter. 2002 Jul-Aug;153(4):243-5.
Title: [Expression of epithelial oncoproteins in large intestine neoplasms].
Author: Bufo, P|Losacco, T|Greco, L|Gagliardi, S|Logrieco, S|Santacroce, L
PMID: 12400211
Journal: Clin Cancer Res. 2003 Nov 1;9(14):5120-6.
Title: Recursive partitioning as an approach to selection of immune markers for tumor diagnosis.
Author: Koziol, James A|Zhang, Jian-Ying|Casiano, Carlos A|Peng, Xuan-Xian|Shi, Fu-Dong|Feng, Anne C|Chan, Edward K L|Tan, Eng M
PMID: 14613989
Journal: World J Gastroenterol. 2005 Mar 28;11(12):1788-92.
Title: p62 Expression in primary carcinomas of the digestive system.
Author: Qian, Hong-Liu|Peng, Xuan-Xian|Chen, Shou-Hui|Ye, Hui-Ming|Qiu, Jing-Hua
PMID: 15793865
Journal: Scand J Immunol. 2009 Jan;69(1):57-63.
Title: Evaluation of tumour-associated antigen (TAA) miniarray in immunodiagnosis of colon cancer.
Author: Liu, W|Wang, P|Li, Z|Xu, W|Dai, L|Wang, K|Zhang, J
PMID: 19140877
Journal: Autophagy. 2010 Feb;6(2):256-69. Epub 2010 Feb 6.
Title: Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells.
Author: Huang, Shengbing|Sinicrope, Frank A
PMID: 20104024
Journal: Eur J Cancer. 2010 Jul;46(10):1900-9.
Title: Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model.
Author: Li, Jie|Hou, Ni|Faried, Ahmad|Tsutsumi, Soichi|Kuwano, Hiroyuki
PMID: 20231086
Journal: Cell Death Differ. 2011 Apr;18(4):602-18.
Title: Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death.
Author: Tang, Y|Chen, Y|Jiang, H|Nie, D
PMID: 20930850
Journal: Autophagy. 2012 Jun;8(6):893-902.
Title: Autophagy is active in normal colon mucosa.
Author: Groulx, Jean-Francois|Khalfaoui, Taoufik|Benoit, Yannick D|Bernatchez, Gerald|Carrier, Julie C|Basora, Nuria|Beaulieu, Jean-Francois
PMID: 22652752
Journal: Apoptosis. 2012 Dec;17(12):1300-15.
Title: DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.
Author: Gandesiri, Muktheshwar|Chakilam, Saritha|Ivanovska, Jelena|Benderska, Natalya|Ocker, Matthias|Di Fazio, Pietro|Feoktistova, Maria|Gali-Muhtasib, Hala|Rave-Frank, Margret|Prante, Olaf|Christiansen, Hans|Leverkus, Martin|Hartmann, Arndt|Schneider-Stock, Reg
PMID: 23011180
Journal: Scand J Immunol. 2013 Apr;77(4):255-60.
Title: Humoral autoimmune response to IGF2 mRNA-binding protein (IMP2/p62) and its tissue-specific expression in colon cancer.
Author: Liu, W|Li, Z|Xu, W|Wang, Q|Yang, S
PMID: 23421499
Journal: Cancer Lett. 2013 Sep 1;337(2):254-65.
Title: Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models.
Author: Adiseshaiah, Pavan P|Clogston, Jeffrey D|McLeland, Christopher B|Rodriguez, Jamie|Potter, Timothy M|Neun, Barry W|Skoczen, Sarah L|Shanmugavelandy, Sriram S|Kester, Mark|Stern, Stephan T|McNeil, Scott E
PMID: 23664889
Journal: Pathol Res Pract. 2013 Apr;209(4):237-43.
Title: Reduced expression of SM22 is correlated with low autophagy activity in human colorectal cancer.
Author: Xie, Xiao-Li|Liu, Ya-Bin|Liu, Yue-Ping|Du, Bin-Liang|Li, Yang|Han, Mei|Li, Bing-Hui
PMID: 23538046
Journal: Cancer Biol Ther. 2013 Feb;14(2):100-7.
Title: Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy.
Author: Park, Jae Myung|Huang, Shengbing|Wu, Tsung-Teh|Foster, Nathan R|Sinicrope, Frank A
PMID: 23192274
Journal: Mol Cell Biochem. 2014 Jan;385(1-2):95-102.
Title: Knockdown of p62/sequestosome 1 attenuates autophagy and inhibits colorectal cancer cell growth.
Author: Ren, Feng|Shu, Guoshun|Liu, Ganglei|Liu, Dongcai|Zhou, Jiapeng|Yuan, Lianwen|Zhou, Jianping
PMID: 24065390
Journal: Apoptosis. 2014 Jun;19(6):1029-42.
Title: WIN induces apoptotic cell death in human colon cancer cells through a block of autophagic flux dependent on PPARgamma down-regulation.
Author: Pellerito, Ornella|Notaro, Antonietta|Sabella, Selenia|De Blasio, Anna|Vento, Renza|Calvaruso, Giuseppe|Giuliano, Michela
PMID: 24696378
Journal: Nat Commun. 2014 Aug 1;5:4557.
Title: AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.
Author: Mojallal, Mahdi|Zheng, Yujuan|Hultin, Sara|Audebert, Stephane|van Harn, Tanja|Johnsson, Per|Lenander, Claes|Fritz, Nicolas|Mieth, Christin|Corcoran, Martin|Lembo, Frederique|Hallstrom, Marja|Hartman, Johan|Mazure, Nathalie M|Weide, Thomas|Grander, Dan|Bor
PMID: 25080976
Journal: Yonsei Med J. 2014 Nov;55(6):1484-8.
Title: Autophagy activity in pulmonary metastatic tumor tissues from colorectal cancer: a pilot study.
Author: Kim, Young Sam|Shin, Ju Hye|Bae, Mi Kyung|Lee, Chang Young|Kim, Dae Joon|Chung, Kyung Young|Lee, Jin Gu
PMID: 25323883
Journal: J Cell Physiol. 2015 Apr;230(4):930-46.
Title: Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
Author: Won, Shen-Jeu|Yen, Cheng-Hsin|Liu, Hsiao-Sheng|Wu, Shan-Ying|Lan, Sheng-Hui|Jiang-Shieh, Ya-Fen|Lin, Chun-Nan|Su, Chun-Li
PMID: 25216025
Journal: Int J Mol Sci. 2015 Jan 9;16(1):1544-61.
Title: Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis.
Author: Amin, Amr|Bajbouj, Khuloud|Koch, Adrian|Gandesiri, Muktheshwar|Schneider-Stock, Regine
PMID: 25584615
Journal: Acta Pharmacol Sin. 2015 Apr;36(4):517-27.
Title: Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro.
Author: Ma, Yi-ming|Han, Wei|Li, Jia|Hu, Li-hong|Zhou, Yu-bo
PMID: 25832431
Journal: Front Oncol. 2015 Mar 30;5:70.
Title: P62/Ubiquitin IHC Expression Correlated with Clinicopathologic Parameters and Outcome in Gastrointestinal Carcinomas.
Author: Mohamed, Amr|Ayman, Alkhoder|Deniece, Johnson|Wang, Tengteng|Kovach, Charles|Siddiqui, Momin T|Cohen, Cynthia
PMID: 25870850
Journal: Oncotarget. 2015 May 20;6(14):12310-25.
Title: Celecoxib increases EGF signaling in colon tumor associated fibroblasts, modulating EGFR expression and degradation.
Author: Vene, Roberta|Tosetti, Francesca|Minghelli, Simona|Poggi, Alessandro|Ferrari, Nicoletta|Benelli, Roberto
PMID: 25987127
Journal: BMC Cancer. 2016 Jan 16;16:23.
Title: A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomal degradation pathway in HT-29 cells.
Author: Dutta, Debasmita|Chakraborty, Biswajit|Sarkar, Ankita|Chowdhury, Chinmay|Das, Padma
PMID: 26772983
Journal: Oncotarget. 2016 Sep 13;7(37):59087-59097.
Title: Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer.
Author: Patel, Sukeshi|Hurez, Vincent|Nawrocki, Steffan T|Goros, Martin|Michalek, Joel|Sarantopoulos, John|Curiel, Tyler|Mahalingam, Devalingam
PMID: 27463016
Journal: World J Surg Oncol. 2016 Jul 22;14(1):189.
Title: Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status.
Author: Schmitz, Klaus Juergen|Ademi, Ceflije|Bertram, Stefanie|Schmid, Kurt Werner|Baba, Hideo Andreas
PMID: 27444698
Journal: Curr Med Chem. 2016;23(11):1171-84.
Title: Non-Photoinduced Biological Properties of Verteporfin.
Author: Gibault, Floriane|Corvaisier, Matthieu|Bailly, Fabrice|Huet, Guillemette|Melnyk, Patricia|Cotelle, Philippe
PMID: 26980565
Journal: Oncotarget. 2016 Feb 23;7(8):9188-221.
Title: BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Author: Goulielmaki, Maria|Koustas, Evangelos|Moysidou, Eirini|Vlassi, Margarita|Sasazuki, Takehiko|Shirasawa, Senji|Zografos, George|Oikonomou, Eftychia|Pintzas, Alexander
PMID: 26802026
Journal: J Nat Prod. 2016 Apr 22;79(4):1097-104.
Title: Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells.
Author: Kim, Won Kyung|Pyee, Yuna|Chung, Hwa-Jin|Park, Hyen Joo|Hong, Ji-Young|Son, Kun Ho|Lee, Sang Kook
PMID: 27064730
Journal: Oncotarget. 2017 Jul 26;8(41):70239-70249.
Title: Alisol B 23-acetate induces autophagic-dependent apoptosis in human colon cancer cells via ROS generation and JNK activation.
Author: Zhao, Yueliang|Li, Edmund T S|Wang, Mingfu
PMID: 29050275
Journal: Sci Rep. 2017 Oct 24;7(1):13912.
Title: Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Author: Dai, Lianzhi|Chen, Xiaolei|Lu, Xiaohong|Wang, Fen|Zhan, Yanyan|Song, Gang|Hu, Tianhui|Xia, Chun|Zhang, Bing
PMID: 29066806
Journal: Cancer Lett. 2017 Dec 1;410:139-157.
Title: Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.
Author: Yagdi Efe, Esma|Mazumder, Aloran|Lee, Jin-Young|Gaigneaux, Anthoula|Radogna, Flavia|Nasim, Muhammad Jawad|Christov, Christo|Jacob, Claus|Kim, Kyu-Won|Dicato, Mario|Chaimbault, Patrick|Cerella, Claudia|Diederich, Marc
PMID: 28943451
Journal: Oncotarget. 2017 May 2;8(33):54604-54615.
Title: Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer.
Author: Niklaus, Monique|Adams, Olivia|Berezowska, Sabina|Zlobec, Inti|Graber, Franziska|Slotta-Huspenina, Julia|Nitsche, Ulrich|Rosenberg, Robert|Tschan, Mario P|Langer, Rupert
PMID: 28903368
Journal: Oncol Rep. 2017 Sep;38(3):1637-1644.
Title: Combination of rapamycin and garlic-derived S-allylmercaptocysteine induces colon cancer cell apoptosis and suppresses tumor growth in xenograft nude mice through autophagy/p62/Nrf2 pathway.
Author: Li, Siying|Yang, Guang|Zhu, Xiaosong|Cheng, Lin|Sun, Yueyue|Zhao, Zhongxi
PMID: 28737825
Journal: Oncoimmunology. 2017 Jan 31;6(3):e1284720.
Title: Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.
Author: Kosumi, Keisuke|Masugi, Yohei|Yang, Juhong|Qian, Zhi Rong|Kim, Sun A|Li, Wanwan|Shi, Yan|da Silva, Annacarolina|Hamada, Tsuyoshi|Liu, Li|Gu, Mancang|Twombly, Tyler S|Cao, Yin|Barbie, David A|Nosho, Katsuhiko|Baba, Hideo|Garrett, Wendy S|Meyerhardt, Jeffer
PMID: 28405513
Journal: Arch Pharm Res. 2017 May;40(5):579-591.
Title: TEOA, a triterpenoid from Actinidia eriantha, induces autophagy in SW620 cells via endoplasmic reticulum stress and ROS-dependent mitophagy.
Author: Zhang, Dandan|Gao, Cuixia|Li, Ruyi|Zhang, Lin|Tian, Jingkui
PMID: 28211011
Journal: Cancer Discov. 2017 Apr;7(4):400-409.
Title: Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1).
Author: Drilon, Alexander|Siena, Salvatore|Ou, Sai-Hong Ignatius|Patel, Manish|Ahn, Myung Ju|Lee, Jeeyun|Bauer, Todd M|Farago, Anna F|Wheler, Jennifer J|Liu, Stephen V|Doebele, Robert|Giannetta, Laura|Cerea, Giulio|Marrapese, Giovanna|Schirru, Michele|Amatu, Ales
PMID: 28183697
Journal: PLoS One. 2017 Feb 2;12(2):e0171351.
Title: Continuous treatment with FTS confers resistance to apoptosis and affects autophagy.
Author: Schmukler, Eran|Wolfson, Eya|Elazar, Zvulun|Kloog, Yoel|Pinkas-Kramarski, Ronit
PMID: 28151959
Journal: Oncotarget. 2017 Jan 24;8(4):6419-6432.
Title: Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells.
Author: Xiong, Li|Liu, Zhipeng|Ouyang, Guoqing|Lin, Liangwu|Huang, He|Kang, Hongxiang|Chen, Wei|Miao, Xiongying|Wen, Yu
PMID: 28031534
Journal: Cancer Med. 2017 Jun;6(6):1264-1274.
Title: p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation.
Author: Nakayama, Shun|Karasawa, Hideaki|Suzuki, Takashi|Yabuuchi, Shinichi|Takagi, Kiyoshi|Aizawa, Takashi|Onodera, Yoshiaki|Nakamura, Yasuhiro|Watanabe, Mika|Fujishima, Fumiyoshi|Yoshida, Hiroshi|Morikawa, Takanori|Sase, Tomohiko|Naitoh, Takeshi|Unno, Michiaki|
PMID: 28544335
Journal: Eur J Pharmacol. 2018 Oct 16. pii: S0014-2999(18)30591-0.
Title: Isoliquiritigenin-mediated p62/SQSTM1 induction regulates apoptotic potential through attenuation of caspase-8 activation in colorectal cancer cells.
Author: Jin, Hao|Seo, Geom Seog|Lee, Sung Hee
PMID: 30339814
Journal: Br J Cancer. 2018 Oct 15. pii: 10.1038/s41416-018-0232-5.
Title: The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death.
Author: Kaliszczak, Maciej|van Hechanova, Erich|Li, Yunqing|Alsadah, Hibah|Parzych, Katarzyna|Auner, Holger W|Aboagye, Eric O
PMID: 30318510
Journal: J Cell Physiol. 2018 Oct 14.
Title: Induction of apoptotic but not autophagic cell death by Cinnamomum cassia extracts on human oral cancer cells.
Author: Yu, Ching-Han|Chu, Shu-Chen|Yang, Shun-Fa|Hsieh, Yih-Shou|Lee, Chih-Yi|Chen, Pei-Ni
PMID: 30317581
Journal: Oncogene. 2018 Oct 1. pii: 10.1038/s41388-018-0513-8.
Title: XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation.
Author: Huang, Xing|Wang, Xiao-Nan|Yuan, Xiao-Dong|Wu, Wen-Yong|Lobie, Peter E|Wu, Zhengsheng
PMID: 30275562
Journal: Cell Death Dis. 2018 Aug 30;9(9):896.
Title: High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling.
Author: Kim, Donghyeok|Choi, Bo-Hyun|Ryoo, In-Geun|Kwak, Mi-Kyoung
PMID: 30166520
Journal: Int J Clin Oncol. 2018 Oct;23(5):917-923.
Title: Multi-panel assay of serum autoantibodies in colorectal cancer.
Author: Ushigome, Mitsunori|Nabeya, Yoshihiro|Soda, Hiroaki|Takiguchi, Nobuhiro|Kuwajima, Akiko|Tagawa, Masatoshi|Matsushita, Kazuyuki|Koike, Junichi|Funahashi, Kimihiko|Shimada, Hideaki
PMID: 29691673
Journal: Mol Cancer Res. 2018 Jul;16(7):1077-1091.
Title: Crosstalk Between Apoptosis and Autophagy Is Regulated by the Arginylated BiP/Beclin-1/p62 Complex.
Author: Song, Xinxin|Lee, Dae-Hee|Dilly, Ashok-Kumar|Lee, Young-Sun|Choudry, Haroon Asif|Kwon, Yong Tae|Bartlett, David L|Lee, Yong J
PMID: 29669822
Journal: Oncol Lett. 2018 Apr;15(4):4463-4470.
Title: Wogonoside inhibits cell growth and induces mitochondrial-mediated autophagy-related apoptosis in human colon cancer cells through the PI3K/AKT/mTOR/p70S6K signaling pathway.
Author: Han, Chengzheng|Xing, Guozheng|Zhang, Mengying|Zhong, Min|Han, Zhen|He, Chiyi|Liu, Xiaoping
PMID: 29541215
Journal: Cell Oncol (Dordr). 2018 Jun;41(3):297-317.
Title: Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.
Author: Gurkan, Ajda Coker|Arisan, Elif Damla|Yerlikaya, Pinar Obakan|Ilhan, Halime|Unsal, Narcin Palavan
PMID: 29492901
Journal: Mol Carcinog. 2018 May;57(5):664-677.
Title: Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of beta-catenin in colon cancer stem cells.
Author: Panda, Prashanta K|Naik, Prajna P|Praharaj, Prakash P|Meher, Biswa R|Gupta, Piyush K|Verma, Rama S|Maiti, Tapas K|Shanmugam, Muthu K|Chinnathambi, Arunachalam|Alharbi, Sulaiman A|Sethi, Gautam|Agarwal, Rajesh|Bhutia, Sujit K
PMID: 29457276
Journal: Biochem Biophys Res Commun. 2018 Jan 29;496(1):159-166.
Title: Autophagy-mediated upregulation of cytoplasmic claudin 1 stimulates the degradation of SQSTM1/p62 under starvation.
Author: Kim, Jaewhan|Choi, Sunkyung|Kim, Jong Ok|Kim, Kee K
PMID: 29307823