Primary Site >> Colorectal Cancer

Gene >> SQSTM1

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Ref: An isolated enriched organ-specific cancer neoantigen of human lung cancer for leukocyte adherence inhibition assays.
PMID: 3886136
Ref: Alteration and enhanced expression of the c-myc oncogene in human colorectal carcinomas.
PMID: 2188234
Ref: Immunohistochemical demonstration of altered intracellular localization of the C-Myc oncogene product in human colorectal neoplasms.
PMID: 2193134
Ref: Lack of prognostic value of immunoreactivity for p62 oncoprotein in colorectal carcinoma.
PMID: 8409682
Ref: DNA ploidy, c-myc oncoprotein p62 and v-H-ras oncoprotein p21 in colorectal carcinoma.
PMID: 8461612
Ref: [Expression of epithelial oncoproteins in large intestine neoplasms].
PMID: 12400211
Ref: Recursive partitioning as an approach to selection of immune markers for tumor diagnosis.
PMID: 14613989
Ref: p62 Expression in primary carcinomas of the digestive system.
PMID: 15793865
Ref: Evaluation of tumour-associated antigen (TAA) miniarray in immunodiagnosis of colon cancer.
PMID: 19140877
Ref: Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells.
PMID: 20104024
Ref: Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model.
PMID: 20231086
Ref: Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death.
PMID: 20930850
Ref: Autophagy is active in normal colon mucosa.
PMID: 22652752
Ref: DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.
PMID: 23011180
Ref: Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy.
PMID: 23192274
Ref: Humoral autoimmune response to IGF2 mRNA-binding protein (IMP2/p62) and its tissue-specific expression in colon cancer.
PMID: 23421499
Ref: Reduced expression of SM22 is correlated with low autophagy activity in human colorectal cancer.
PMID: 23538046
Ref: Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models.
PMID: 23664889
Ref: Knockdown of p62/sequestosome 1 attenuates autophagy and inhibits colorectal cancer cell growth.
PMID: 24065390
Ref: WIN induces apoptotic cell death in human colon cancer cells through a block of autophagic flux dependent on PPARgamma down-regulation.
PMID: 24696378
Ref: AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.
PMID: 25080976
Ref: Autophagy activity in pulmonary metastatic tumor tissues from colorectal cancer: a pilot study.
PMID: 25323883
Ref: Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
PMID: 25216025
Ref: Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis.
PMID: 25584615
Ref: Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro.
PMID: 25832431
Ref: P62/Ubiquitin IHC Expression Correlated with Clinicopathologic Parameters and Outcome in Gastrointestinal Carcinomas.
PMID: 25870850
Ref: Celecoxib increases EGF signaling in colon tumor associated fibroblasts, modulating EGFR expression and degradation.
PMID: 25987127
Ref: A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomal degradation pathway in HT-29 cells.
PMID: 26772983
Ref: BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
PMID: 26802026
Ref: Non-Photoinduced Biological Properties of Verteporfin.
PMID: 26980565
Ref: Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells.
PMID: 27064730
Ref: Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status.
PMID: 27444698
Ref: Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer.
PMID: 27463016
Ref: Autophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells.
PMID: 28031534
Ref: Continuous treatment with FTS confers resistance to apoptosis and affects autophagy.
PMID: 28151959
Ref: Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1).
PMID: 28183697
Ref: TEOA, a triterpenoid from Actinidia eriantha, induces autophagy in SW620 cells via endoplasmic reticulum stress and ROS-dependent mitophagy.
PMID: 28211011
Ref: Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.
PMID: 28405513
Ref: p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation.
PMID: 28544335
Ref: Combination of rapamycin and garlic-derived S-allylmercaptocysteine induces colon cancer cell apoptosis and suppresses tumor growth in xenograft nude mice through autophagy/p62/Nrf2 pathway.
PMID: 28737825
Ref: Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer.
PMID: 28903368
Ref: Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.
PMID: 28943451
Ref: Alisol B 23-acetate induces autophagic-dependent apoptosis in human colon cancer cells via ROS generation and JNK activation.
PMID: 29050275
Ref: Phosphoinositide-specific phospholipase Cgamma1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
PMID: 29066806
Ref: Autophagy-mediated upregulation of cytoplasmic claudin 1 stimulates the degradation of SQSTM1/p62 under starvation.
PMID: 29307823
Ref: Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of beta-catenin in colon cancer stem cells.
PMID: 29457276
Ref: Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.
PMID: 29492901
Ref: Wogonoside inhibits cell growth and induces mitochondrial-mediated autophagy-related apoptosis in human colon cancer cells through the PI3K/AKT/mTOR/p70S6K signaling pathway.
PMID: 29541215
Ref: Crosstalk Between Apoptosis and Autophagy Is Regulated by the Arginylated BiP/Beclin-1/p62 Complex.
PMID: 29669822
Ref: Multi-panel assay of serum autoantibodies in colorectal cancer.
PMID: 29691673
Ref: High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling.
PMID: 30166520
Ref: XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation.
PMID: 30275562
Ref: Induction of apoptotic but not autophagic cell death by Cinnamomum cassia extracts on human oral cancer cells.
PMID: 30317581
Ref: The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death.
PMID: 30318510
Ref: Isoliquiritigenin-mediated p62/SQSTM1 induction regulates apoptotic potential through attenuation of caspase-8 activation in colorectal cancer cells.
PMID: 30339814