Primary Site >> Liver Cancer

Gene >> SPP1

1.
Journal: Gan To Kagaku Ryoho. 2000 Jul;27(8):1191-200.
Title: [Tumor microcirculation and selective enhancement of drug delivery--clinical applications based on pathophysiological experiments].
Author: Sato, H|Hori, K|Sugiyama, K|Tanda, S|Sato, Y
PMID: 10945016
2.
Journal: Pathol Int. 2002 Jan;52(1):19-24.
Title: Overexpression of osteopontin in hepatocellular carcinoma.
Author: Gotoh, Masahiro|Sakamoto, Michiie|Kanetaka, Kengo|Chuuma, Makoto|Hirohashi, Setsuo
PMID: 11940202
3.
Journal: Zhonghua Yi Xue Za Zhi. 2002 Jul 25;82(14):970-3.
Title: [Expression of osteopontin mRNA and its protein in colorectal cancer and liver metastatic tissues].
Author: Ding, Ling|Zheng, Shu|Cao, Jiang
PMID: 12181091
4.
Journal: Zhonghua Wai Ke Za Zhi. 2002 Oct;40(10):773-5.
Title: [Expression and clinical significance of osteopontin in colorectal cancer and liver metastatic tissues].
Author: Ding, Ling|Zheng, Shu
PMID: 12487883
5.
Journal: Cancer. 2003 Jul 1;98(1):119-27.
Title: Overexpression of osteopontin is associated with intrahepatic metastasis, early recurrence, and poorer prognosis of surgically resected hepatocellular carcinoma.
Author: Pan, Hung-Wei|Ou, Yueh-Hsing|Peng, Shian-Yang|Liu, Shu-Hsian|Lai, Po-Lin|Lee, Po-Hwaung|Sheu, Jin-Chuan|Chen, Chi-Ling|Hsu, Hey-Chi
PMID: 12833464
6.
Journal: Zhonghua Yi Xue Za Zhi. 2003 Nov 25;83(22):1980-3.
Title: [EGF/PI3K signaling pathway regulates the expression of osteopontin in liver cancer HepG2 cells].
Author: Zhang, Guo-xin|Zhao, Zhi-quan|Lin, Xiu-wen
PMID: 14703434
7.
Journal: World J Gastroenterol. 2004 Jan 15;10(2):205-8.
Title: Enhancement of osteopontin expression in HepG2 cells by epidermal growth factor via phosphatidylinositol 3-kinase signaling pathway.
Author: Zhang, Guo-Xin|Zhao, Zhi-Quan|Wang, Hong-Di|Hao, Bo
PMID: 14716823
8.
Journal: Nihon Rinsho. 2004 Aug;62 Suppl 8:74-8.
Title: [Hepatitis/hepatocellular carcinoma and OPN/Eta-1].
Author: Uede, Toshimitsu|Morimoto, Junko|Kon, Shigeyuki
PMID: 15453290
9.
Journal: Int J Oncol. 2005 Apr;26(4):1053-61.
Title: Aberrant expressions of annexin A10 short isoform, osteopontin and alpha-fetoprotein at chromosome 4q cooperatively contribute to progression and poor prognosis of hepatocellular carcinoma.
Author: Peng, Shian-Yang|Ou, Yueh-Hsing|Chen, Wei J|Li, Huei-Ying|Liu, Shu-Hsiang|Pan, Hung-Wei|Lai, Po-Lin|Jeng, Yung-Ming|Chen, David C P|Hsu, Hey-Chi
PMID: 15754002
10.
Journal: Dig Dis Sci. 2005 Jul;50(7):1288-98.
Title: Nitric oxide-dependent osteopontin expression induces metastatic behavior in HepG2 cells.
Author: Guo, Hongtao|Marroquin, Carlos E|Wai, Philip Y|Kuo, Paul C
PMID: 16047475
11.
Journal: Cancer Biol Ther. 2005 Nov;4(11):1192-4. Epub 2005 Nov 10.
Title: Elevated Serum Levels of Osteopontin in HCV-Associated Lymphoproliferative Disorders.
Author: Libra, Massimo|Indelicato, Manuela|De Re, Valli|Zignego, Anna Linda|Chiocchetti, Annalisa|Malaponte, Grazia|Dianzani, Umberto|Nicoletti, Ferdinando|Stivala, Franca|McCubrey, James A|Mazzarino, Maria C
PMID: 16177564
12.
Journal: Zhonghua Wai Ke Za Zhi. 2005 Aug 1;43(15):985-8.
Title: [The prognostic significance of preoperative plasma level of osteopontin in combination with intercellular adhesion molecule-1 for patients with hepatocellular carcinoma].
Author: Zhang, Hui|Ren, Ning|Ye, Qing-hai|Sun, Hui-chuan|Wang, Lu|Liu, Yin-kun|Tang, Zhao-you|Qin, Lun-xiu
PMID: 16194354
13.
Journal: J Surg Oncol. 2005 Dec 15;92(4):304-11.
Title: Loss of E-cadherin mRNA and gain of osteopontin mRNA are useful markers for detecting early recurrence of HCV-related hepatocellular carcinoma.
Author: Iso, Yukihiro|Sawada, Tokihiko|Okada, Toshie|Kubota, Keiichi
PMID: 16299806
14.
Journal: Gastroenterology. 2005 Dec;129(6):2064-75.
Title: Liver gene expression signature of mild fibrosis in patients with chronic hepatitis C.
Author: Asselah, Tarik|Bieche, Ivan|Laurendeau, Ingrid|Paradis, Valerie|Vidaud, Dominique|Degott, Claude|Martinot, Michelle|Bedossa, Pierre|Valla, Dominique|Vidaud, Michel|Marcellin, Patrick
PMID: 16344072
15.
Journal: FEBS Lett. 2006 Jun 26;580(15):3571-81.
Title: Correlation between genomic DNA copy number alterations and transcriptional expression in hepatitis B virus-associated hepatocellular carcinoma.
Author: Huang, Jian|Sheng, Hai-Hui|Shen, Ting|Hu, Yuan-Jie|Xiao, Hua-Sheng|Zhang, Qin|Zhang, Qing-Hua|Han, Ze-Guang
PMID: 16750200
16.
Journal: J Cancer Res Clin Oncol. 2006 Nov;132(11):709-17.
Title: The prognostic significance of preoperative plasma levels of osteopontin in patients with hepatocellular carcinoma.
Author: Zhang, Hui|Ye, Qing-Hai|Ren, Ning|Zhao, Lei|Wang, Yan-Fang|Wu, Xin|Sun, Hui-Chuan|Wang, Lu|Zhang, Bo-Heng|Liu, Yin-Kun|Tang, Zhao-You|Qin, Lun-Xiu
PMID: 16786357
17.
Journal: Ai Zheng. 2006 Jul;25(7):876-9.
Title: [Osteopontin as a potential biomarker of metastasis and recurrence for hepatocellular carcinoma].
Author: Cui, Bo-Kang|Zhang, Chang-Qing|Zhang, Ying|Yuan, Yun-Fei|Zhang, Ya-Qi|Shi, Ming|Chen, Min-Shan|Li, Sheng-Ping|Li, Jin-Qing
PMID: 16831281
18.
Journal: Am J Gastroenterol. 2006 Sep;101(9):2051-9.
Title: Elevated plasma osteopontin levels in patients with hepatocellular carcinoma.
Author: Kim, Jin|Ki, Seung S|Lee, Sang D|Han, Chul J|Kim, Yu C|Park, Sun H|Cho, Soo Y|Hong, Young-Joon|Park, Hyo Y|Lee, Myoungjin|Jung, Ha H|Lee, Kee H|Jeong, Sook-Hyang
PMID: 16848813
19.
Journal: Oncol Rep. 2006 Nov;16(5):1137-42.
Title: Different molecular pathways determining extrahepatic and intrahepatic recurrences of hepatocellular carcinoma.
Author: Iizuka, Norio|Tamesa, Takao|Sakamoto, Kazuhiko|Miyamoto, Takanobu|Hamamoto, Yoshihiko|Oka, Masaaki
PMID: 17016605
20.
Journal: Zhonghua Zhong Liu Za Zhi. 2006 Jun;28(6):404-7.
Title: [Knocking down osteopontin expression by specific siRNA reduces the in vitro invasiveness of human hepatocellular carcinoma cells].
Author: Zhu, Xiao-Qun|Ye, Qing-Hai|Lei, Ke-Feng|Chen, Jie|Qin, Lun-Xiu
PMID: 17152482
21.
Journal: Zhonghua Gan Zang Bing Za Zhi. 2007 Jan;15(1):37-40.
Title: [Osteopontin promotes the malignant phenotypes of human hepatocellular carcinoma cell line SMMC-7721].
Author: Chen, Rong-xin|Xue, Tong-chun|Ye, Sheng-long|Sun, Rui-xia|Zhao, Yan|Tang, Zhao-you
PMID: 17244457
22.
Journal: Oncogene. 2007 Sep 27;26(44):6361-71.
Title: An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma.
Author: Takafuji, V|Forgues, M|Unsworth, E|Goldsmith, P|Wang, X W
PMID: 17452979
23.
Journal: Int J Epidemiol. 2007 Oct;36(5):1001-8.
Title: SPP1 polymorphisms associated with HBV clearance and HCC occurrence.
Author: Shin, Hyoung Doo|Park, Byung Lae|Cheong, Hyun Sub|Yoon, Jung-Hwan|Kim, Yoon Jun|Lee, Hyo-Suk
PMID: 17496055
24.
Journal: Cancer Res. 2007 Jun 1;67(11):5141-7.
Title: Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells.
Author: Cheng, Jiasen|Huo, De-Hua|Kuang, Dong-Ming|Yang, Jine|Zheng, Limin|Zhuang, Shi-Mei
PMID: 17545592
25.
Journal: Cancer Biol Ther. 2007 Oct;6(10):1532-8. Epub 2007 Jul 5.
Title: Identification of candidate biomarkers for hepatocellular carcinoma through pre-cancerous expression analysis in an HBx transgenic mouse.
Author: Sun, Qiang|Zhang, Yingai|Liu, Fang|Zhao, Xiaohang|Yang, Xiao
PMID: 18245957
26.
Journal: Int J Clin Pract. 2008 Jul;62(7):1056-62.
Title: Elevated plasma osteopontin level is predictive of cirrhosis in patients with hepatitis B infection.
Author: Zhao, L|Li, T|Wang, Y|Pan, Y|Ning, H|Hui, X|Xie, H|Wang, J|Han, Y|Liu, Z|Fan, D
PMID: 17537188
27.
Journal: Toxicol Sci. 2008 May;103(1):4-13.
Title: Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer.
Author: Ramaiah, Shashi K|Rittling, Susan
PMID: 17890765
28.
Journal: Eur J Cancer. 2008 Apr;44(6):885-97.
Title: Molecular mapping of human hepatocellular carcinoma provides deeper biological insight from genomic data.
Author: Kittaka, Nobuyoshi|Takemasa, Ichiro|Takeda, Yutaka|Marubashi, Shigeru|Nagano, Hiroaki|Umeshita, Koji|Dono, Keizo|Matsubara, Kenichi|Matsuura, Nariaki|Monden, Morito
PMID: 18337085
29.
Journal: Hepatology. 2008 Jul;48(1):265-75.
Title: Thirty-kilodalton Tat-interacting protein suppresses tumor metastasis by inhibition of osteopontin transcription in human hepatocellular carcinoma.
Author: Zhao, Jian|Lu, Bin|Xu, Hao|Tong, Xin|Wu, Guobin|Zhang, Xia|Liang, Anmin|Cong, Wenming|Dai, Jianxin|Wang, Hao|Wu, Mengchao|Guo, Yajun
PMID: 18537194
30.
Journal: Surgery. 2008 Jun;143(6):803-12.
Title: RNA stability regulates differential expression of the metastasis protein, osteopontin, in hepatocellular cancer.
Author: Emani, Sirisha|Zhang, Jinping|Guo, Lucie|Guo, Hongtao|Kuo, Paul C
PMID: 18549897
31.
Journal: Cancer Biol Ther. 2008 Mar;7(3):387-91.
Title: High-resolution analysis of genomic profiles of hepatocellular carcinoma cells with differential osteopontin expression.
Author: Sun, Bingsheng|Wu, Jincai|Zhang, Ti|Wang, Changli
PMID: 18717013
32.
Journal: Hepatology. 2008 Dec;48(6):1834-42.
Title: Lentiviral-mediated miRNA against osteopontin suppresses tumor growth and metastasis of human hepatocellular carcinoma.
Author: Sun, Bing-Sheng|Dong, Qiong-Zhu|Ye, Qing-Hai|Sun, Hai-Jing|Jia, Hu-Liang|Zhu, Xiao-Qun|Liu, Dao-Yong|Chen, Jie|Xue, Qiong|Zhou, Hai-Jun|Ren, Ning|Qin, Lun-Xiu
PMID: 18972404
33.
Journal: Oncologist. 2008 Nov;13(11):1155-65.
Title: Osteopontin combined with CD44, a novel prognostic biomarker for patients with hepatocellular carcinoma undergoing curative resection.
Author: Yang, Guo-Huan|Fan, Jia|Xu, Yang|Qiu, Shuang-Jian|Yang, Xin-Rong|Shi, Guo-Ming|Wu, Bing|Dai, Zhi|Liu, Yin-Kun|Tang, Zhao-You|Zhou, Jian
PMID: 18997126
34.
Journal: Transplant Proc. 2008 Nov;40(9):3182-4.
Title: Role of osteopontin and CD44s expression for patients with hepatocellular carcinoma undergoing liver transplantation or resection.
Author: Beckebaum, S|Chen, X|Sotiropoulos, G C|Radtke, A|Daoudaki, M|Baba, H A|Wohlschlaeger, J|Broelsch, C E|Gerken, G|Cicinnati, V R
PMID: 19010227
35.
Journal: Zhonghua Gan Zang Bing Za Zhi. 2009 Jun;17(6):422-5.
Title: [Interference of osteopontin expression inhibits the invasion and metastasis of human hepatocellular carcinoma cell lines].
Author: Lin, Fan|Li, Yu-yuan|Xia, Jin-tang|Wen, Min-jie|Lai, Yue-yuan|Cai, Wen-song|Wu, Zhao-feng|Fan, Shao-feng
PMID: 19567019
36.
Journal: Korean J Hepatol. 2009 Sep;15(3):320-30.
Title: Prognostic value of serum osteopontin in hepatocellular carcinoma patients treated with transarterial chemoembolization.
Author: Kim, Sung Hoon|Chung, Young Hwa|Yang, Soo Hyun|Kim, Jeong A|Jang, Myoung Kuk|Kim, Sung Eun|Lee, Danbi|Lee, Sae Hwan|Lee, Don|Kim, Kang Mo|Lim, Young Suk|Lee, Han Chu|Lee, Yung Sang|Suh, Dong Jin
PMID: 19783881
37.
Journal: Int J Oncol. 2009 Dec;35(6):1409-16.
Title: Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines.
Author: Chae, Sujin|Jun, Hyoung-Oh|Lee, Eun Gyo|Yang, Suk-Jin|Lee, Dong Chul|Jung, Joon Ki|Park, Kyung Chan|Yeom, Young Il|Kim, Kyu-Won
PMID: 19885563
38.
Journal: J Cancer Res Clin Oncol. 2010 Apr;136(4):595-601.
Title: Genomic aberrations in hepatocellular carcinoma related to osteopontin expression detected by array-CGH.
Author: Wu, Jin-Cai|Sun, Bing-Sheng|Ren, Ning|Ye, Qing-Hai|Qin, Lun-Xiu
PMID: 19834740
39.
Journal: Hepatology. 2010 Jan;51(1):255-66.
Title: Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression.
Author: Quiles-Perez, Rosa|Munoz-Gamez, Jose Antonio|Ruiz-Extremera, Angeles|O'Valle, Francisco|Sanjuan-Nunez, Laura|Martin-Alvarez, Ana Belen|Martin-Oliva, David|Caballero, Trinidad|Munoz de Rueda, Paloma|Leon, Josefa|Gonzalez, Raul|Muntane, Jordi|Oliver, Franci
PMID: 20034026
40.
Journal: Surg Today. 2010 Apr;40(4):347-56.
Title: Inhibition of osteopontin reduces liver metastasis of human pancreatic cancer xenografts injected into the spleen in a mouse model.
Author: Ohno, Keisuke|Nishimori, Hidefumi|Yasoshima, Takahiro|Kamiguchi, Kenjiro|Hata, Fumitake|Fukui, Rika|Okuya, Koichi|Kimura, Yasutoshi|Denno, Ryuichi|Kon, Shigeyuki|Uede, Toshimitsu|Sato, Noriyuki|Hirata, Koichi
PMID: 20339989
41.
Journal: Cancer Sci. 2010 May;101(5):1314-9.
Title: Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection.
Author: Huang, Hua|Zhang, Xiao-Fei|Zhou, Hai-Jun|Xue, Yu-Hua|Dong, Qiong-Zhu|Ye, Qing-Hai|Qin, Lun-Xiu
PMID: 20345480
42.
Journal: Acta Pharmacol Sin. 2010 May;31(5):593-600.
Title: A mutant of hepatitis B virus X protein (HBx Delta 127) enhances hepatoma cell migration via osteopontin involving 5-lipoxygenase.
Author: Zhang, Xuan|Ye, Li-hong|Zhang, Xiao-dong
PMID: 20364155
43.
Journal: Proc Natl Acad Sci U S A. 2010 May 4;107(18):8357-62.
Title: Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma.
Author: Yoo, Byoung Kwon|Emdad, Luni|Gredler, Rachel|Fuller, Christine|Dumur, Catherine I|Jones, Kimberly H|Jackson-Cook, Colleen|Su, Zao-Zhong|Chen, Dong|Saxena, Utsav H|Hansen, Ulla|Fisher, Paul B|Sarkar, Devanand
PMID: 20404171
44.
Journal: World J Surg. 2010 Aug;34(8):1930-6.
Title: Increased osteopontin-positive macrophage expression in colorectal cancer stroma with synchronous liver metastasis.
Author: Imano, Motohiro|Okuno, Kiyokata|Itoh, Tatsuki|Ishimaru, Eizaburo|Satou, Takao|Shiozaki, Hitoshi
PMID: 20414778
45.
Journal: Surgery. 2010 Aug;148(2):291-7.
Title: Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines.
Author: Bhattacharya, Syamal D|Garrison, Juline|Guo, Hongtao|Mi, Zhiyong|Markovic, Jovan|Kim, Victoria M|Kuo, Paul C
PMID: 20576283
46.
Journal: J Gastroenterol Hepatol. 2010 Aug;25(8):1435-42.
Title: Osteopontin, a single marker for predicting the prognosis of patients with tumor-node-metastasis stage I hepatocellular carcinoma after surgical resection.
Author: Chen, Rong-Xin|Xia, Yun-Hong|Cui, Jie-Feng|Xue, Tong-Chun|Ye, Sheng-Long
PMID: 20659235
47.
Journal: Hepatology. 2010 Dec;52(6):2012-22.
Title: Thrombin is a therapeutic target for metastatic osteopontin-positive hepatocellular carcinoma.
Author: Xue, Yu-Hua|Zhang, Xiao-Fei|Dong, Qiong-Zhu|Sun, Jian|Dai, Chun|Zhou, Hai-Jun|Ren, Ning|Jia, Hu-Liang|Ye, Qin-Hai|Qin, Lun-Xiu
PMID: 20890897
48.
Journal: Arch Med Res. 2010 Oct;41(7):541-7.
Title: Clinical significance of plasma osteopontin level in Egyptian patients with hepatitis C virus-related hepatocellular carcinoma.
Author: El-Din Bessa, Sahar Saad|Elwan, Nadia Mohamed|Suliman, Ghada Abdul Moemen|El-Shourbagy, Safinaz Hamdy
PMID: 21167394
49.
Journal: J Exp Clin Cancer Res. 2010 Dec 30;29:172.
Title: Transcription factor c-Myb promotes the invasion of hepatocellular carcinoma cells via increasing osteopontin expression.
Author: Chen, Rong-Xin|Xia, Yun-Hong|Xue, Tong-Chun|Ye, Sheng-Long
PMID: 21190594
50.
Journal: J Hepatol. 2011 Jan;54(1):89-97.
Title: Osteopontin expression predicts overall survival after liver transplantation for hepatocellular carcinoma in patients beyond the Milan criteria.
Author: Sieghart, Wolfgang|Wang, Xiaowei|Schmid, Katharina|Pinter, Matthias|Konig, Franz|Bodingbauer, Martin|Wrba, Fritz|Rasoul-Rockenschaub, Susanne|Peck-Radosavljevic, Markus
PMID: 20970216
51.
Journal: Mol Biol Rep. 2011 Aug;38(6):3671-7.
Title: Osteopontin promotes hepatocellular carcinoma invasion by up-regulating MMP-2 and uPA expression.
Author: Chen, Rong-Xin|Xia, Yun-Hong|Xue, Tong-Chun|Ye, Sheng-Long
PMID: 21104439
52.
Journal: Oncol Rep. 2011 Mar;25(3):803-8.
Title: Down-regulation of osteopontin inhibits metastasis of hepatocellular carcinoma cells via a mechanism involving MMP-2 and uPA.
Author: Chen, Rong-Xin|Xia, Yun-Hong|Xue, Tong-Chun|Zhang, Hong|Ye, Sheng-Long
PMID: 21174062
53.
Journal: Mol Biol Rep. 2011 Nov;38(8):5205-10.
Title: Overexpression of osteopontin in hepatocellular carcinoma and its relationships with metastasis, invasion of tumor cells.
Author: Lin, Fan|Li, Yuyuan|Cao, Jie|Fan, Shaofeng|Wen, Jifeng|Zhu, Guanghui|Du, Hong|Liang, Yanxiao
PMID: 21188534
54.
Journal: Zhonghua Gan Zang Bing Za Zhi. 2011 Jan;19(1):48-51.
Title: [Relative analysis of OPN and its related signal molecules in hepatocellular carcinoma].
Author: Zhang, Lan|Li, Hai-yu|Yin, Xiao-lu|Xu, Yan-ping|Chen, Yi|Xie, Xiao-ying|Shen, Yue-fang|Ye, Qing-hai|Ren, Zheng-gang
PMID: 21272459
55.
Journal: Surgery. 2011 Jun;149(6):783-91.
Title: Specific expression of osteopontin and S100A6 in hepatocellular carcinoma.
Author: Hua, Zhan|Chen, Jingzhou|Sun, Baishun|Zhao, Gonghua|Zhang, Yuanchun|Fong, Yuman|Jia, Zhengeng|Yao, Li
PMID: 21310450
56.
Journal: Tohoku J Exp Med. 2011 May;224(1):29-39.
Title: Osteopontin as a key mediator for vasculogenic mimicry in hepatocellular carcinoma.
Author: Liu, Wenbin|Xu, Geliang|Ma, Jinliang|Jia, Weidong|Li, Jiansheng|Chen, Ke|Wang, Wei|Hao, Chen|Wang, Yongcang|Wang, Xiujun
PMID: 21512310
57.
Journal: Ann Hepatol. 2011 Jul-Sep;10(3):296-305.
Title: Diagnostic significance of plasma osteopontin in hepatitis C virus-related hepatocellular carcinoma.
Author: Abu El Makarem, Mona A|Abdel-Aleem, Ashraf|Ali, Ahmed|Saber, Rafet|Shatat, Mohammed|Rahem, Doaa Abdel|Sayed, Douaa
PMID: 21677331
58.
Journal: Oncol Rep. 2011 Oct;26(4):825-31.
Title: Serum levels of beta-catenin as a potential marker for genotype 4/hepatitis C-associated hepatocellular carcinoma.
Author: Zekri, Abdel-Rahman N|Bahnassy, Abeer A|Alam El-Din, Hanaa M|Morsy, Heba M|Shaarawy, Sabry|Moharram, Nagia Z|Daoud, Sayed S
PMID: 21701780
59.
Journal: J Hepatol. 2011 Dec;55(6):1317-24.
Title: c-Met activation through a novel pathway involving osteopontin mediates oncogenesis by the transcription factor LSF.
Author: Yoo, Byoung Kwon|Gredler, Rachel|Chen, Dong|Santhekadur, Prasanna K|Fisher, Paul B|Sarkar, Devanand
PMID: 21703197
60.
Journal: Zhonghua Gan Zang Bing Za Zhi. 2011 Dec;19(12):904-7.
Title: [Identification of metastasis-related osteopontin expression and glycosylation in hepatocellular carcinoma].
Author: Sun, Hai-yan|Li, Yan|Guo, Kun|Kang, Xiao-nan|Sun, Chun|Liu, Yin-kun
PMID: 22525502
61.
Journal: Int J Cancer. 2012 Jun 1;130(11):2685-92.
Title: Prognostic significance of osteopontin in hepatocellular carcinoma: a meta-analysis.
Author: Zhang, Chuan-Hai|Xu, Ge-Liang|Jia, Wei-Dong|Ge, Yong-Sheng|Li, Jian-Sheng|Ma, Jin-Liang|Ren, Wei-Hua
PMID: 21780114
62.
Journal: Ann Surg Oncol. 2012 Jul;19 Suppl 3:S455-63.
Title: Recurrence and poor prognosis following resection of small hepatitis B-related hepatocellular carcinoma lesions are associated with aberrant tumor expression profiles of glypican 3 and osteopontin.
Author: Yu, Ming-Chin|Lee, Yun-Shien|Lin, Sey-En|Wu, Hsiang-Yao|Chen, Tse-Ching|Lee, Wei-Chen|Chen, Miin-Fu|Tsai, Chi-Neu
PMID: 21822558
63.
Journal: Hepatology. 2012 Feb;55(2):483-90.
Title: Identification of osteopontin as a novel marker for early hepatocellular carcinoma.
Author: Shang, Sufen|Plymoth, Amelie|Ge, Shaokui|Feng, Ziding|Rosen, Hugo R|Sangrajrang, Suleeporn|Hainaut, Pierre|Marrero, Jorge A|Beretta, Laura
PMID: 21953299
64.
Journal: Ann Surg. 2012 Feb;255(2):319-25.
Title: Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model.
Author: Bhattacharya, Syamal D|Mi, Zhiyong|Kim, Victoria M|Guo, Hongtao|Talbot, Lindsay J|Kuo, Paul C
PMID: 22241292
65.
Journal: BMC Med Genomics. 2012 Jan 27;5:5.
Title: Global analysis of DNA methylation in early-stage liver fibrosis.
Author: Komatsu, Yoko|Waku, Tsuyoshi|Iwasaki, Naoya|Ono, Wakana|Yamaguchi, Chie|Yanagisawa, Junn
PMID: 22281153
66.
Journal: PLoS One. 2012;7(2):e31458.
Title: Hepatitis B virus X protein drives multiple cross-talk cascade loops involving NF-kappaB, 5-LOX, OPN and Capn4 to promote cell migration.
Author: Zhang, Xuan|You, Xiaona|Wang, Qi|Zhang, Tao|Du, Yumei|Lv, Na|Zhang, Zhao|Zhang, Shuai|Shan, Changliang|Ye, Lihong|Zhang, Xiaodong
PMID: 22355367
67.
Journal: J Exp Clin Cancer Res. 2012 Mar 23;31:26.
Title: Osteopontin induces growth of metastatic tumors in a preclinical model of non-small lung cancer.
Author: Shojaei, Farbod|Scott, Nathan|Kang, Xiaolin|Lappin, Patrick B|Fitzgerald, Amanda A|Karlicek, Shannon|Simmons, Brett H|Wu, Aidong|Lee, Joseph H|Bergqvist, Simon|Kraynov, Eugenia
PMID: 22444159
68.
Journal: Mol Cancer. 2012 May 8;11:31.
Title: Interferon-alpha enhances antitumor activities of oncolytic adenovirus-mediated IL-24 expression in hepatocellular carcinoma.
Author: Wang, Cong-Jun|Xiao, Chao-Wen|You, Tian-Geng|Zheng, Ya-Xin|Gao, Wei|Zhou, Zhu-Qing|Chen, Jun|Xue, Xin-Bo|Fan, Jia|Zhang, Hui
PMID: 22569271
69.
Journal: Am J Cancer Res. 2012;2(3):269-85. Epub 2012 Apr 21.
Title: The transcription factor LSF: a novel oncogene for hepatocellular carcinoma.
Author: Santhekadur, Prasanna K|Rajasekaran, Devaraja|Siddiq, Ayesha|Gredler, Rachel|Chen, Dong|Schaus, Scott E|Hansen, Ulla|Fisher, Paul B|Sarkar, Devanand
PMID: 22679558
70.
Journal: World J Gastroenterol. 2012 Jul 14;18(26):3389-99.
Title: Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner.
Author: Phillips, Renee J|Helbig, Karla J|Van der Hoek, Kylie H|Seth, Devanshi|Beard, Michael R
PMID: 22807608
71.
Journal: Semin Oncol. 2012 Aug;39(4):410-33.
Title: Hepatocellualar carcinoma serum markers.
Author: Bertino, Gaetano|Ardiri, Annalisa|Malaguarnera, Michele|Malaguarnera, Giulia|Bertino, Nicoletta|Calvagno, Giuseppe Stefano
PMID: 22846859
72.
Journal: World J Gastroenterol. 2012 Aug 14;18(30):3923-30.
Title: Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers.
Author: Cao, Dong-Xing|Li, Zhi-Jie|Jiang, Xiao-Ou|Lum, Yick Liang|Khin, Ester|Lee, Nikki P|Wu, Guo-Hao|Luk, John M
PMID: 22912540
73.
Journal: PLoS One. 2012;7(8):e42976.
Title: Breast cancer metastasis suppressor 1 regulates hepatocellular carcinoma cell apoptosis via suppressing osteopontin expression.
Author: Wu, Yanhua|Jiang, Wenjun|Wang, Yingming|Wu, Jun|Saiyin, Hexige|Qiao, Xiaojing|Mei, Xinyu|Guo, Bin|Fang, Xiao|Zhang, Lu|Lou, Huiling|Wu, Chaoqun|Qiao, Shouyi
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Journal: Chin J Physiol. 2012 Dec 31;55(6):412-20.
Title: Association between Osteopontin and EGFR Expression with Clinicopathological Parameters in Hepatocellular Carcinoma.
Author: Tsai, Wen-Chiuan|Tsai, Wen-Chiuan|Lee, Herng-Sheng|Jin, Jong-Shiaw|Gao, Hong-Wei|Chao, Tai-Kuang|Chen, Ann|Nieh, Shi|Chan, De-Chuan|Chang, Fei-Ni|Lin, Chih-Kung
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75.
Journal: Hepatology. 2013 Mar;57(3):1024-34.
Title: Osteopontin promoter polymorphisms at locus -443 significantly affect the metastasis and prognosis of human hepatocellular carcinoma.
Author: Dong, Qiong-Zhu|Zhang, Xiao-Fei|Zhao, Yue|Jia, Hu-Liang|Zhou, Hai-Jun|Dai, Chun|Sun, Hai-Jing|Qin, Yi|Zhang, Wei-De|Ren, Ning|Ye, Qing-Hai|Qin, Lun-Xiu
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Journal: J Vet Med Sci. 2013;75(3):299-307. Epub 2012 Oct 30.
Title: Canonical Wnt signaling pathway plays an essential role in N-methyl-N-nitrosurea induced gastric tumorigenesis of mice.
Author: Heo, Seung-Ho|Jeong, Eui-Suk|Lee, Kyoung-Sun|Seo, Jin-Hee|Jeong, Dong-Gu|Won, Young-Suk|Kwon, Hyo-Jung|Kim, Hyoung-Chin|Kim, Dae-Yong|Choi, Yang-Kyu
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77.
Journal: Ann Surg Oncol. 2013 Mar;20(3):929-37.
Title: Postoperative serum osteopontin level is a novel monitor for treatment response and tumor recurrence after resection of hepatitis B-related hepatocellular carcinoma.
Author: Zhou, Chuang|Zhou, Hai-Jun|Zhang, Xiao-Fei|Lou, Li-Li|Ye, Qing-Hai|Zheng, Yan|Wang, Ji|Zhu, Hai-Tao|Dong, Qiong-Zhu|Jia, Hu-Liang|Zhu, Wen-Wei|Guo, Lei|Zhao, Yue|Gao, Dong-Mei|Qin, Lun-Xiu
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Journal: J Cell Biochem. 2013 Sep;114(9):1987-96.
Title: Suppressive effect of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) on hepatitis C virus replication.
Author: Sato, Ayami|Saito, Yoshimasa|Sugiyama, Kazuo|Sakasegawa, Noriko|Muramatsu, Toshihide|Fukuda, Shinya|Yoneya, Mikiko|Kimura, Masaki|Ebinuma, Hirotoshi|Hibi, Toshifumi|Ikeda, Masanori|Kato, Nobuyuki|Saito, Hidetsugu
PMID: 23519646
79.
Journal: Liver Int. 2013 Aug;33(7):1100-12.
Title: Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma.
Author: Tomimaru, Yoshito|Koga, Hironori|Yano, Hirohisa|de la Monte, Suzanne|Wands, Jack R|Kim, Miran
PMID: 23651211
80.
Journal: Exp Ther Med. 2013 May;5(5):1403-1407.
Title: Effect of thalidomide on the proliferation of hepatoma cells assessed by osteopontin levels in nude mice.
Author: Lin, Fan|Cao, Jie|Huang, Zhiming|Pei, Zhenghao|Gu, Weili|Fan, Shaofeng|Li, Kunping|Weng, Jiefeng
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Journal: Clin Exp Metastasis. 2013 Oct;30(7):903-18.
Title: Development and characterization of a reliable mouse model of colorectal cancer metastasis to the liver.
Author: Zhang, Yu|Davis, Celestia|Ryan, James|Janney, Cory|Pena, Maria Marjorette O
PMID: 23748471
82.
Journal: Sci China Life Sci. 2013 Jul;56(7):638-46.
Title: Secretory/releasing proteome-based identification of plasma biomarkers in HBV-associated hepatocellular carcinoma.
Author: Yang, Lei|Rong, Weiqi|Xiao, Ting|Zhang, Ying|Xu, Bin|Liu, Yu|Wang, Liming|Wu, Fan|Qi, Jun|Zhao, Xiuying|Wang, Hongxia|Han, Naijun|Guo, Suping|Wu, Jianxiong|Gao, Yanning|Cheng, Shujun
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Journal: Oncol Rep. 2013 Dec;30(6):2795-803.
Title: Correlation and prognostic value of osteopontin and Bcl-2 in hepatocellular carcinoma patients after curative resection.
Author: Deng, Biao|Zhang, Xiao-Fei|Zhu, Xu-Chao|Huang, Hua|Jia, Hu-Liang|Ye, Qing-Hai|Dong, Qiong-Zhu|Qin, Lun-Xiu
PMID: 24065086
84.
Journal: Eur J Med Res. 2013 Sep 30;18:34.
Title: Effect of bone-marrow-derived mesenchymal stem cells on high-potential hepatocellular carcinoma in mouse models: an intervention study.
Author: Li, Tianran|Song, Bin|Du, Xiangke|Wei, Zhengmao|Huo, Tianlong
PMID: 24079479
85.
Journal: J Biol Chem. 2013 Dec 27;288(52):36994-7009.
Title: Mechanism of hepatitis C virus (HCV)-induced osteopontin and its role in epithelial to mesenchymal transition of hepatocytes.
Author: Iqbal, Jawed|McRae, Steven|Banaudha, Krishna|Mai, Thi|Waris, Gulam
PMID: 24240095
86.
Journal: Hepatol Int. 2013 Jun;7(2):683-92.
Title: SNPs in the promoter region of the osteopontin gene as a possible host factor for sex difference in hepatocellular carcinoma development in patients with HCV.
Author: Hamaoka, Kazuhiro|Nagoshi, Sumiko|Sugawara, Kayoko|Naiki, Kayoko|Uchida, Yoshihito|Inao, Mie|Nakayama, Nobuaki|Fujiwara, Kenji|Mochida, Satoshi
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Journal: Gastroenterology Res. 2013 Oct;6(5):191-199.
Title: Clinical Significance of Plasma Osteopontin Level as a Biomarker of Hepatocellular Carcinoma.
Author: Salem, Mona|Atti, Sahar Abdel|Raziky, Maisa El|Darweesh, Samar Kamal|Sharkawy, Marwa El
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Journal: Hepatol Res. 2014 Jan;44(1):22-30.
Title: Osteopontin: Versatile modulator of liver diseases.
Author: Nagoshi, Sumiko
PMID: 23701387
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Journal: J Clin Gastroenterol. 2014 Oct;48(9):806-14.
Title: Meta-analysis of the prognostic and diagnostic significance of serum/plasma osteopontin in hepatocellular carcinoma.
Author: Cheng, JiWen|Wang, WanLi|Sun, CaiHong|Li, MuXing|Wang, Bo|Lv, Yi
PMID: 24247813
90.
Journal: Ann Surg Oncol. 2014 Apr;21(4):1304-13.
Title: Combination of osteopontin with peritumoral infiltrating macrophages is associated with poor prognosis of early-stage hepatocellular carcinoma after curative resection.
Author: Zhu, Wenwei|Guo, Lei|Zhang, Bo|Lou, Lili|Lin, Zhenghai|Zhu, Xiaodong|Ren, Ning|Dong, Qiongzhu|Ye, Qinghai|Qin, Lunxiu
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Journal: Front Med. 2014 Mar;8(1):24-32.
Title: Osteopontin is a promoter for hepatocellular carcinoma metastasis: a summary of 10 years of studies.
Author: Qin, Lunxiu
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92.
Journal: PLoS One. 2014 Jan 31;9(1):e87464.
Title: Role of hepatitis C virus induced osteopontin in epithelial to mesenchymal transition, migration and invasion of hepatocytes.
Author: Iqbal, Jawed|McRae, Steven|Mai, Thi|Banaudha, Krishna|Sarkar-Dutta, Mehuli|Waris, Gulam
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Journal: PLoS One. 2014 Feb 3;9(2):e87930.
Title: OPN and alphavbeta3 expression are predictors of disease severity and worse prognosis in hepatocellular carcinoma.
Author: Jin, Yi|Chen, Jian-ning|Feng, Zhi-ying|Zhang, Zhi-gang|Fan, Wen-zhe|Wang, Yu|Li, Jia-ping
PMID: 24498405
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Journal: PLoS One. 2014 Mar 10;9(3):e88543.
Title: Dynamic expression patterns of differential proteins during early invasion of hepatocellular carcinoma.
Author: Chen, Rong-Xin|Song, Hai-Yan|Dong, Yin-Ying|Hu, Chao|Zheng, Qiong-Dan|Xue, Tong-Chun|Liu, Xiao-Hui|Zhang, Yang|Chen, Jie|Ren, Zheng-Gang|Liu, Yin-Kun|Cui, Jie-Feng
PMID: 24614035
95.
Journal: Gut Liver. 2014 Mar;8(2):177-85.
Title: Clinical utility of plasma glypican-3 and osteopontin as biomarkers of hepatocellular carcinoma.
Author: Lee, Hyun Jung|Yeon, Jong Eun|Suh, Sang Jun|Lee, Sun Jae|Yoon, Eileen L|Kang, Keunhee|Yoo, Yang Jae|Kim, Ji Hoon|Seo, Yeon Seok|Yim, Hyung Joon|Byun, Kwan Soo
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96.
Journal: Hepatobiliary Surg Nutr. 2014 Apr;3(2):57-9.
Title: Can combination of osteopontin and peritumor-infiltrating macrophages be a prognostic marker of early-stage hepatocellular carcinoma?
Author: Lee, Yoo Jin|Jang, Byoung Kuk
PMID: 24812596
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Journal: Hepatobiliary Surg Nutr. 2014 Apr;3(2):98-101.
Title: Importance of tumor/stroma interactions in prognosis of hepatocellular carcinoma.
Author: Eiro, Noemi|Vizoso, Francisco J
PMID: 24812604
98.
Journal: Hepatogastroenterology. 2014 Mar-Apr;61(130):405-9.
Title: Long-term outcome of laparoscopic hepatectomy in patients with hepatocellular carcinoma.
Author: Kamiyama, Toshiya|Tahara, Munenori|Nakanishi, Kazuaki|Yokoo, Hideki|Kamachi, Hirofumi|Kakisaka, Tatsuhiko|Tsuruga, Yosuke|Matsushita, Michiaki|Todo, Satoru
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Journal: Int J Clin Exp Pathol. 2014 Apr 15;7(5):2527-35. eCollection 2014.
Title: Screening candidate metastasis-associated genes in three-dimensional HCC spheroids with different metastasis potential.
Author: Chen, Rongxin|Dong, Yinying|Xie, Xiaoying|Chen, Jie|Gao, Dongmei|Liu, Yinkun|Ren, Zhenggang|Cui, Jiefeng
PMID: 24966965
100.
Journal: Biochim Biophys Acta. 2014 Sep;1839(9):837-48.
Title: Osteopontin enhances the expression of HOTAIR in cancer cells via IRF1.
Author: Yang, Guang|Zhang, Shenghong|Gao, Fei|Liu, Zhenyin|Lu, Mingjian|Peng, Sheng|Zhang, Tao|Zhang, Fujun
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Journal: Hepatobiliary Surg Nutr. 2014 Jun;3(3):112-4.
Title: OPN sesame.
Author: Liang, Kung-Hao|Yeh, Chau-Ting
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Journal: Clin Res Hepatol Gastroenterol. 2014 Dec;38(6):706-14.
Title: Comparison osteopontin vs AFP for the diagnosis of HCC: a meta-analysis.
Author: Wan, Hao-Guang|Xu, Hao|Gu, Yu-Ming|Wang, Hui|Xu, Wei|Zu, Mao-Heng
PMID: 25034355
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Journal: Oncol Rep. 2014 Oct;32(4):1550-6.
Title: Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma.
Author: Ying, Xia|Zhao, Yue|Wang, Jun-Lan|Zhou, Xia|Zhao, Jing|He, Chen-Chen|Guo, Xi-Jing|Jin, Gui-Hua|Wang, Li-Juan|Zhu, Qing|Han, Su-Xia
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Journal: Int J Oncol. 2014 Nov;45(5):1883-90.
Title: Spatial localization of the JAG1/Notch1/osteopontin cascade modulates extrahepatic metastasis in hepatocellular carcinoma.
Author: Xue, Tong-Chun|Zou, Jing-Huai|Chen, Rong-Xin|Cui, Jie-Feng|Tang, Zhao-You|Ye, Sheng-Long
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Journal: Arab J Gastroenterol. 2014 Sep-Dec;15(3-4):103-7.
Title: Significance of plasma osteopontin in diagnosis of hepatitis C virus-related hepatocellular carcinoma.
Author: Nabih, Mona I|Aref, Wael M|Fathy, Mona M
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Journal: Int J Cancer. 2015 Jan 1;136(1):172-81.
Title: Osteopontin and latent-TGF beta binding-protein 2 as potential diagnostic markers for HBV-related hepatocellular carcinoma.
Author: da Costa, Andre Nogueira|Plymoth, Amelie|Santos-Silva, Daniela|Ortiz-Cuaran, Sandra|Camey, Suzy|Guilloreau, Paule|Sangrajrang, Suleeporn|Khuhaprema, Thiravud|Mendy, Maimuna|Lesi, Olufunmilayo A|Chang, Hee-Kyung|Oh, Jin-Kyoung|Lee, Duk-Hee|Shin, Hai-Rim|Ki
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Journal: Drug Dev Ind Pharm. 2015;41(7):1193-203.
Title: A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment.
Author: Bao, Xu|Gao, Meng|Xu, Hong|Liu, Ke-Xin|Zhang, Cheng-Hong|Jiang, Ni|Chu, Qiu-Chen|Guan, Xin|Tian, Yan
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Journal: Cancer Res. 2015 Jan 1;75(1):86-97.
Title: Intracellular Osteopontin inhibits toll-like receptor signaling and impedes liver carcinogenesis.
Author: Fan, Xiaoyu|He, Chunyan|Jing, Wei|Zhou, Xuyu|Chen, Rui|Cao, Lei|Zhu, Minhui|Jia, Rongjie|Wang, Hao|Guo, Yajun|Zhao, Jian
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Journal: Cancer Lett. 2015 Jan 28;356(2 Pt B):713-20.
Title: Hepatic stellate cells activated by acidic tumor microenvironment promote the metastasis of hepatocellular carcinoma via osteopontin.
Author: Song, Jin|Ge, Zhouhong|Yang, Xinrong|Luo, Qin|Wang, Cun|You, Haiyan|Ge, Tianxiang|Deng, Yun|Lin, Hechun|Cui, Yongqi|Chu, Wei|Yao, Ming|Zhang, Zhigang|Gu, Jianren|Fan, Jia|Qin, Wenxin
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Journal: Med Oncol. 2015 Mar;32(3):59.
Title: Diagnostic values of alpha-fetoprotein, dickkopf-1, and osteopontin for hepatocellular carcinoma.
Author: Ge, Tianxiang|Shen, Qiujin|Wang, Ning|Zhang, Yurong|Ge, Zhouhong|Chu, Wei|Lv, Xiufang|Zhao, Fengbo|Zhao, Weifeng|Fan, Jia|Qin, Wenxin
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Journal: Genet Mol Res. 2015 Feb 20;14(1):1502-7.
Title: Multivariate analysis of molecular markers in peripheral blood associated with recurrence and metastasis of hepatocellular carcinoma.
Author: Liu, X J|Wang, B|Jiang, W G|Li, Y J|Liu, J B|Zhang, M
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112.
Journal: Oncotarget. 2015 Mar 30;6(9):6627-40.
Title: Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin-NF-kappaB-HIF-1alpha pathway.
Author: Cao, Lei|Fan, Xiaoyu|Jing, Wei|Liang, Yingchao|Chen, Rui|Liu, Yingying|Zhu, Minhui|Jia, Rongjie|Wang, Hao|Zhang, Xueguang|Zhang, Yanyun|Zhou, Xuyu|Zhao, Jian|Guo, Yajun
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Journal: PLoS One. 2015 Mar 11;10(3):e0118744.
Title: Serum osteopontin predicts degree of hepatic fibrosis and serves as a biomarker in patients with hepatitis C virus infection.
Author: Matsue, Yasuhiro|Tsutsumi, Mikihiro|Hayashi, Nobuhiko|Saito, Takashi|Tsuchishima, Mutsumi|Toshikuni, Nobuyuki|Arisawa, Tomiyasu|George, Joseph
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Journal: Anticancer Res. 2015 Apr;35(4):2021-8.
Title: Gene expression analysis for evaluation of potential biomarkers in hepatocellular carcinoma.
Author: Hass, Holger G|Jobst, Juergen|Scheurlen, Michael|Vogel, Ulrich|Nehls, Oliver
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Journal: Eur J Med Res. 2015 May 24;20:56.
Title: Effects of transforming growth factor beta-1 infected human bone marrow mesenchymal stem cells on high- and low-metastatic potential hepatocellular carcinoma.
Author: Li, Tianran|Zhao, Shaohong|Song, Bin|Wei, Zhengmao|Lu, Guangming|Zhou, Jun|Huo, Tianlong
PMID: 26003220
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Journal: Stem Cells. 2015 Dec;33(12):3569-80.
Title: Osteopontin Promotes Hepatic Progenitor Cell Expansion and Tumorigenicity via Activation of beta-Catenin in Mice.
Author: Liu, Yingying|Cao, Lei|Chen, Rui|Zhou, Xuyu|Fan, Xiaoyu|Liang, Yingchao|Jia, Rongjie|Wang, Hao|Liu, Guoke|Guo, Yajun|Zhao, Jian
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Journal: BMC Gastroenterol. 2015 Jun 30;15:73.
Title: Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis, not for hepatocellular carcinoma screening.
Author: Simao, Adelia|Madaleno, Joao|Silva, Nuno|Rodrigues, Fernando|Caseiro, Paula|Costa, Jose Nascimento|Carvalho, Armando
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Journal: Surgery. 2015 Oct;158(4):1039-47; discussion 1047-8.
Title: Green tea component epigallocatechin-3-gallate decreases expression of osteopontin via a decrease in mRNA half-life in cell lines of metastatic hepatocellular carcinoma.
Author: Zapf, Matthew A C|Kothari, Anai N|Weber, Cynthia E|Arffa, Matthew L|Wai, Phillip Y|Driver, Joseph|Gupta, Gopal N|Kuo, Paul C|Mi, Zhiyong
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Journal: PLoS One. 2015 Aug 17;10(8):e0134243.
Title: Higher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin beta1/GSK3beta/beta-Catenin Signaling Pathway.
Author: You, Yang|Zheng, Qiongdan|Dong, Yinying|Wang, Yaohui|Zhang, Lan|Xue, Tongchun|Xie, Xiaoying|Hu, Chao|Wang, Zhiming|Chen, Rongxin|Wang, Yanhong|Cui, Jiefeng|Ren, Zhenggang
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Journal: Oncol Rep. 2015 Dec;34(6):3297-303.
Title: Overexpression of osteopontin promotes resistance to cisplatin treatment in HCC.
Author: Ding, Kun|Fan, Lu|Chen, Shijun|Wang, Yanna|Yu, Haifeng|Sun, Yanni|Yu, Jiguang|Wang, Li|Liu, Xiangzhong|Liu, Youde
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Journal: Hepat Mon. 2015 Sep 1;15(9):e30753.
Title: Plasma Osteopontin Level in Chronic Liver Disease and Hepatocellular Carcinoma.
Author: Fouad, Shawky Abdelhamid|Mohamed, Nagwa Abdel Ghaffar|Fawzy, Mary Wadie|Moustafa, Doaa Ali
PMID: 26500684
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Journal: Asian Pac J Cancer Prev. 2015;16(16):7211-7.
Title: Diagnostic and Prognostic Roles of Serum Osteopontin and Osteopontin Promoter Polymorphisms in Hepatitis B-related Hepatocellular Carcinoma.
Author: Chimparlee, Nitinan|Chuaypen, Natthaya|Khlaiphuengsin, Apichaya|Pinjaroen, Nutcha|Payungporn, Sunchai|Poovorawan, Yong|Tangkijvanich, Pisit
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Journal: Genet Mol Res. 2015 Nov 19;14(4):14440-7.
Title: Segment-specific targeting via RNA interference mediates down-regulation of OPN expression in hepatocellular carcinoma cells.
Author: Lin, F|Huang, C M|Cao, J|Pei, Z H|Gu, W L|Fan, S F|Li, K P|Lin, C M
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Journal: Cell Death Differ. 2016 Apr;23(4):576-82.
Title: The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice.
Author: Trierweiler, C|Hockenjos, B|Zatloukal, K|Thimme, R|Blum, H E|Wagner, E F|Hasselblatt, P
PMID: 26470729
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Journal: Cell Oncol (Dordr). 2016 Apr;39(2):119-28.
Title: Down-regulation of osteopontin mediates a novel mechanism underlying the cytostatic activity of TGF-beta.
Author: Zhang, Jing|Yamada, Osamu|Kida, Shinya|Matsushita, Yoshihisa|Hattori, Toshio
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Journal: Int J Oncol. 2016 Feb;48(2):533-40.
Title: Epigenetic regulation of proliferation and invasion in hepatocellular carcinoma cells by CBP/p300 histone acetyltransferase activity.
Author: Inagaki, Yuji|Shiraki, Katsuya|Sugimoto, Kazushi|Yada, Takazumi|Tameda, Masahiko|Ogura, Suguru|Yamamoto, Norihiko|Takei, Yoshiyuki|Ito, Masaaki
PMID: 26676548
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Journal: Oncotarget. 2016 Mar 15;7(11):12997-3012.
Title: Osteopontin promotes epithelial-mesenchymal transition of hepatocellular carcinoma through regulating vimentin.
Author: Dong, Qiongzhu|Zhu, Xuchao|Dai, Chun|Zhang, Xiaofei|Gao, Xiaomei|Wei, Jinwang|Sheng, Yuanyuan|Zheng, Yan|Yu, Jian|Xie, Lu|Qin, Yi|Qiao, Peng|Zhou, Chuang|Yu, Xinxin|Jia, Huliang|Ren, Ning|Zhou, Haijun|Ye, Qinghai|Qin, Lunxiu
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Journal: Asian Pac J Cancer Prev. 2016;17(1):201-5.
Title: Clinicopathological Significance of Osteopontin in Cholangiocarcinoma Cases.
Author: Laohaviroj, Marut|Chamgramol, Yaovalux|Pairojkul, Chawalit|Mulvenna, Jason|Sripa, Banchob
PMID: 26838210
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Journal: PLoS One. 2016 Mar 17;11(3):e0151069.
Title: Diagnostic Performance of Alpha-Fetoprotein, Protein Induced by Vitamin K Absence, Osteopontin, Dickkopf-1 and Its Combinations for Hepatocellular Carcinoma.
Author: Jang, Eun Sun|Jeong, Sook-Hyang|Kim, Jin-Wook|Choi, Yun Suk|Leissner, Philippe|Brechot, Christian
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Journal: PLoS One. 2016 May 24;11(5):e0155800.
Title: Midkine Increases Diagnostic Yield in AFP Negative and NASH-Related Hepatocellular Carcinoma.
Author: Vongsuvanh, Roslyn|van der Poorten, David|Iseli, Tristan|Strasser, Simone I|McCaughan, Geoffrey W|George, Jacob
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Journal: Cancer Prev Res (Phila). 2016 Sep;9(9):758-65.
Title: Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population.
Author: Duarte-Salles, Talita|Misra, Sandeep|Stepien, Magdalena|Plymoth, Amelie|Muller, David|Overvad, Kim|Olsen, Anja|Tjonneland, Anne|Baglietto, Laura|Severi, Gianluca|Boutron-Ruault, Marie-Christine|Turzanski-Fortner, Renee|Kaaks, Rudolf|Boeing, Heiner|Aleksan
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Journal: Genet Test Mol Biomarkers. 2016 Sep;20(9):535-43.
Title: Risk Factors for Hepatocellular Carcinoma in Cirrhotic Patients with Chronic Hepatitis B.
Author: Zhang, Yuan-Qing|Peng, Li-Jun|Cao, Yi-Rong|Zeng, Zhi-Ping|Wu, Yu-Jing|Shi, Hong|Cheng, Shi-Yao|Wang, Ji-Yao|Friedman, Scott L|Sninsky, John J|Guo, Jin-Sheng
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Journal: Sci Rep. 2016 Jul 26;6:30489.
Title: SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma.
Author: Kawai, Takayuki|Yasuchika, Kentaro|Ishii, Takamichi|Miyauchi, Yuya|Kojima, Hidenobu|Yamaoka, Ryoya|Katayama, Hokahiro|Yoshitoshi, Elena Yukie|Ogiso, Satoshi|Kita, Sadahiko|Yasuda, Katsutaro|Fukumitsu, Ken|Komori, Junji|Hatano, Etsuro|Kawaguchi, Yoshiya|Ue
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Journal: Int J Biol Sci. 2016 Aug 6;12(9):1121-8.
Title: Role of Osteopontin in Liver Diseases.
Author: Wen, Yankai|Jeong, Seogsong|Xia, Qiang|Kong, Xiaoni
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Journal: J Genet. 2016 Sep;95(3):741-50.
Title: Comparative analysis of gene expression profiles of OPN signaling pathway in four kinds of liver diseases.
Author: Wang, Gaiping|Chen, Shasha|Zhao, Congcong|Li, Xiaofang|Zhao, Weiming|Yang, Jing|Chang, Cuifang|Xu, Cunshuan
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Journal: Cancer Lett. 2016 Dec 28;383(2):171-182.
Title: Osteopontin induces autophagy to promote chemo-resistance in human hepatocellular carcinoma cells.
Author: Liu, Guoke|Fan, Xiaoyu|Tang, Min|Chen, Rui|Wang, Hao|Jia, Rongjie|Zhou, Xuyu|Jing, Wei|Wang, Huajing|Yang, Yang|Yin, Fan|Wei, Huafeng|Li, Bohua|Zhao, Jian
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Journal: Am J Cancer Res. 2016 Sep 1;6(9):1873-1889. eCollection 2016.
Title: Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression.
Author: Wang, Chao-Qun|Sun, Hao-Ting|Gao, Xiao-Mei|Ren, Ning|Sheng, Yuan-Yuan|Wang, Zheng|Zheng, Yan|Wei, Jin-Wang|Zhang, Kai-Li|Yu, Xin-Xin|Zhu, Yin|Luo, Qin|Yang, Lu-Yu|Dong, Qiong-Zhu|Qin, Lun-Xiu
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Journal: Anticancer Res. 2016 Oct;36(10):5087-5095.
Title: Gene-expression Analysis Identifies Specific Patterns of Dysregulated Molecular Pathways and Genetic Subgroups of Human Hepatocellular Carcinoma.
Author: Hass, Holger G|Vogel, Ulrich|Scheurlen, Michael|Jobst, Jurgen
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Journal: Oncotarget. 2016 Dec 27;7(52):87219-87231.
Title: Suppression of osteopontin inhibits chemically induced hepatic carcinogenesis by induction of apoptosis in mice.
Author: Lee, Su-Hyung|Park, Jun-Won|Woo, Sang-Ho|Go, Du-Min|Kwon, Hyo-Jung|Jang, Ja-June|Kim, Dae-Yong
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Journal: Electron Physician. 2017 Jan 25;9(1):3492-3498.
Title: Serum Midkine and Osteopontin Levels as Diagnostic Biomarkers of Hepatocellular Carcinoma.
Author: Hodeib, Hossam|ELshora, Ola|Selim, Amal|Sabry, Nesreen Mohammed|El-Ashry, Heba Mohamed
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Title: Diagnostic accuracy of osteopontin plus alpha-fetoprotein in the hepatocellular carcinoma: A meta-analysis.
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Journal: Int J Oncol. 2017 May;50(5):1760-1766.
Title: Characterization of DAPK1 as a novel transcriptional target of BRMS1.
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Journal: PLoS One. 2017 Apr 19;12(4):e0173376.
Title: Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.
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Journal: Asian Pac J Cancer Prev. 2017 Apr 1;18(4):863-872.
Title: Hepatocellular Carcinoma: a Comprehensive Review of Biomarkers, Clinical Aspects, and Therapy
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Journal: Gastroenterol Hepatol Bed Bench. 2017 Spring;10(2):97-101.
Title: Measuring levels of osteopontin as potential biomarker for hepatocellular carcinoma in Syrian patients.
Author: Al-Zoubi, Sara|Wassouf, Ahmad|Zetoune, Almoutassem Billah
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Title: Osteopontin in hepatocellular carcinoma: A possible biomarker for diagnosis and follow-up.
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Journal: Cancer Med. 2017 Aug;6(8):1976-1987.
Title: Transcriptome analysis in primary colorectal cancer tissues from patients with and without liver metastases using next-generation sequencing.
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Title: Osteopontin -- a promising biomarker for cancer therapy.
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Journal: Oncotarget. 2017 Jul 22;8(39):65789-65799.
Title: Up-regulation of brain-expressed X-linked 2 is critical for hepatitis B virus X protein-induced hepatocellular carcinoma development.
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Title: CCN3 is a therapeutic target relating enhanced stemness and coagulation in hepatocellular carcinoma.
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Journal: Chin Med J (Engl). 2017 Nov 5;130(21):2591-2600.
Title: Magnetic Resonance Gd-RGD Imaging Study of Hepatocellular Carcinoma with High and Low Metastatic Potential before and after Human Bone Marrow-derived Mesenchymal Stem Cell Intervention.
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Journal: Oncol Lett. 2017 Dec;14(6):6578-6584.
Title: Delisheng induces antiproliferation and apoptosis effects in Hep3B cells via modulation of angiogenic proteins.
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Journal: Oncol Lett. 2017 Dec;14(6):7045-7048.
Title: Improved treatment of early small hepatocellular carcinoma using sorafenib in combination with radiofrequency ablation.
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Journal: Brief Bioinform. 2018 Jan 1;19(1):101-108.
Title: Genome-wide DNA methylation analysis identifies candidate epigenetic markers and drivers of hepatocellular carcinoma.
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Journal: Cancer Sci. 2018 Mar;109(3):710-723.
Title: C-C chemokine receptor type 1 mediates osteopontin-promoted metastasis in hepatocellular carcinoma.
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Title: Regulator of G-protein signaling 5 enhances portal vein invasion in hepatocellular carcinoma.
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Journal: J Virol. 2018 Jun 13;92(13). pii: JVI.02116-17.
Title: Osteopontin Regulates Hepatitis C Virus (HCV) Replication and Assembly by Interacting with HCV Proteins and Lipid Droplets and by Binding to Receptors alphaVbeta3 and CD44.
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Title: Evaluation of Osteopontin as a Biomarker in Hepatocellular Carcinomas in Egyptian Patients with Chronic HCV Cirrhosis
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Title: A novel mechanism of the M1-M2 methionine adenosyltransferase switch-mediated hepatocellular carcinoma metastasis.
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Title: Long-term prognostic impact of osteopontin and Dickkopf-related protein 1 in patients with hepatocellular carcinoma after hepatectomy.
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Title: Post-surgical resection prognostic value of combined OPN, MMP7, and PSG9 plasma biomarkers in hepatocellular carcinoma.
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Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
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Title: Supervised learning reveals circulating biomarker levels diagnostic of hepatocellular carcinoma in a clinically relevant model of non-alcoholic steatohepatitis; An OAD to NASH.
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Title: Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44+ cancer stem cells to 5 azacytidine in hepatocellular carcinoma.
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Journal: Life Sci. 2018 Sep 15;209:259-266.
Title: Luteolin induces caspase-dependent apoptosis via inhibiting the AKT/osteopontin pathway in human hepatocellular carcinoma SK-Hep-1 cells.
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Journal: Sci Rep. 2018 Sep 3;8(1):13143.
Title: The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication.
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Journal: Oncotarget. 2018 Aug 24;9(66):32624-32641.
Title: Quantitative screening of serum protein biomarkers by reverse phase protein arrays.
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Title: A four-gene-based prognostic model predicts overall survival in patients with hepatocellular carcinoma.
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Title: Osteopontin promotes hepatocellular carcinoma progression via the PI3K/AKT/Twist signaling pathway.
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