Primary Site >> Colorectal Cancer

Gene >> SPINK1

Journal: Int J Pancreatol. 1988 Jul;3(5):323-31.
Title: The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
Author: Satake, K|Inui, A|Sogabe, T|Yoshii, Y|Nakata, B|Tanaka, H|Chung, Y S|Hiura, A|Umeyama, K
PMID: 2459273
Journal: Minerva Med. 1989 Mar;80(3):199-203.
Title: [Determination of tumor-associated trypsin inhibitor (TATI) in subjects with gastrointestinal diseases. Preliminary data].
Author: Piantino, P|Mosso, R|Polloni, R|Cerchier, A|Gennaretti, G|Daziano, E
PMID: 2717042
Journal: Jpn J Med. 1990 Jul-Aug;29(4):391-6.
Title: Rearrangement, amplification and overexpression of c-Ha Ras gene in premalignant lesion of Turcot's syndrome.
Author: Minami, T|Himeno, S|Shinomura, Y|Kariya, Y|Tarui, S|Sakurai, M
PMID: 1703248
Journal: Cancer. 1990 Nov 15;66(10):2144-9.
Title: Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
Author: Tomita, N|Doi, S|Higashiyama, M|Morimoto, H|Murotani, M|Kawasaki, Y|Monden, T|Shimano, T|Horii, A|Yokouchi, H
PMID: 2224769
Journal: Br J Cancer. 1990 Dec;62(6):954-8.
Title: Expression of pancreatic secretory trypsin inhibitor (PSTI) in colorectal cancer.
Author: Higashiyama, M|Monden, T|Tomita, N|Murotani, M|Kawasaki, Y|Morimoto, H|Murata, A|Shimano, T|Ogawa, M|Mori, T
PMID: 2257226
Journal: Cancer Res. 1991 Oct 1;51(19):5329-38.
Title: Folate-binding protein is a marker for ovarian cancer.
Author: Campbell, I G|Jones, T A|Foulkes, W D|Trowsdale, J
PMID: 1717147
Journal: Scand J Clin Lab Invest Suppl. 1991;207:25-32.
Title: Evaluation of TATI and other markers in solid tumors.
Author: Taccone, W|Mazzon, W|Belli, M
PMID: 1780686
Journal: Scand J Clin Lab Invest Suppl. 1991;207:43-6.
Title: Tumor-associated trypsin inhibitor (TATI) in patients with colorectal carcinoma. A critical comparison with CEA.
Author: Catarino, M|Conde, R
PMID: 1780689
Journal: Scand J Clin Lab Invest Suppl. 1991;207:67-9.
Title: Tumor-associated trypsin inhibitor, TATI, in gastrointestinal cancer and related benign diseases.
Author: Piantino, P|Arosaio, E
PMID: 1780697
Journal: Int J Cancer. 1991 Feb 20;47(4):592-6.
Title: Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen.
Author: Koivunen, E|Saksela, O|Itkonen, O|Osman, S|Huhtala, M L|Stenman, U H
PMID: 1995487
Journal: Cancer Res. 1991 Apr 15;51(8):2107-12.
Title: Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Author: Koivunen, E|Ristimaki, A|Itkonen, O|Osman, S|Vuento, M|Stenman, U H
PMID: 2009530
Journal: Biochem J. 1992 Aug 1;285 ( Pt 3):915-23.
Title: Sequence of the complete cDNA and the 5' structure of the human sucrase-isomaltase gene. Possible homology with a yeast glucoamylase.
Author: Chantret, I|Lacasa, M|Chevalier, G|Ruf, J|Islam, I|Mantei, N|Edwards, Y|Swallow, D|Rousset, M
PMID: 1353958
Journal: J Med Screen. 1994 Jan;1(1):60-4.
Title: Tumour markers and screening for gastrointestinal cancer: a follow up study in Finland.
Author: Hakama, M|Stenman, U H|Knekt, P|Jarvisalo, J|Leino, A|Hakulinen, T|Maatela, J|Aromaa, A
PMID: 8790487
Journal: Scand J Clin Lab Invest. 1995 Apr;55(2):119-24.
Title: Tumour-associated trypsin inhibitor (TATI) in patients with colorectal cancer: a comparison with CEA, CA 50 and CA 242.
Author: Pasanen, P|Eskelinen, M|Kulju, A|Penttila, I|Janatuinen, E|Alhava, E
PMID: 7667604
Journal: Histol Histopathol. 2003 Oct;18(4):1181-8.
Title: Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Author: Solakidi, S|Tiniakos, D G|Petraki, K|Stathopoulos, G P|Markaki, I|Androulakis, G|Sekeris, C E
PMID: 12973686
Journal: Cancer Biol Ther. 2003 Nov-Dec;2(6):652-5.
Title: Polymorphisms of SPINK1 N34S and CFTR in patients with sporadic and familial pancreatic cancer.
Author: Matsubayashi, Hiroyuki|Fukushima, Noriyoshi|Sato, Norihiro|Brune, Kieran|Canto, Marcia|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E|Goggins, Michael
PMID: 14688470
Journal: Clin Biochem. 2004 Jan;37(1):56-60.
Title: Tumour-associated trypsin inhibitor, carcinoembryonic antigen and acute-phase reactant proteins CRP and alpha1-antitrypsin in patients with gastrointestinal malignancies.
Author: Solakidi, Sylvia|Dessypris, Athanassios|Stathopoulos, George P|Androulakis, George|Sekeris, Constantine E
PMID: 14675563
Journal: Zhonghua Yu Fang Yi Xue Za Zhi. 2004 May;38(3):162-6.
Title: [Genetic polymorphism in cytochrome P450 2E1, salted food and colorectal cancer susceptibility: a case-control study].
Author: Yu, Wei-ping|Chen, Kun|Ma, Xin-yuan|Yao, Kai-yan|Jiang, Qin-ting|Zou, Yan|Zhou, Hai-guang
PMID: 15182482
Journal: Oncogene. 2008 Jul 3;27(29):4024-33.
Title: Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Author: Gouyer, V|Fontaine, D|Dumont, P|de Wever, O|Fontayne-Devaud, H|Leteurtre, E|Truant, S|Delacour, D|Drobecq, H|Kerckaert, J-P|de Launoit, Y|Bracke, M|Gespach, C|Desseyn, J-L|Huet, G
PMID: 18317448
Journal: Br J Cancer. 2009 May 19;100(10):1540-8.
Title: High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Author: Gaber, A|Johansson, M|Stenman, U-H|Hotakainen, K|Ponten, F|Glimelius, B|Bjartell, A|Jirstrom, K|Birgisson, H
PMID: 19384300
Journal: World J Gastroenterol. 2010 Jun 21;16(23):2949-53.
Title: CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis.
Author: Zhou, Guo-Wu|Hu, Jia|Li, Qiang
PMID: 20556843
Journal: BMC Cancer. 2010 Sep 17;10:498.
Title: Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
Author: Gaber, Alexander|Nodin, Bjorn|Hotakainen, Kristina|Nilsson, Elise|Stenman, Ulf-Hakan|Bjartell, Anders|Birgisson, Helgi|Jirstrom, Karin
PMID: 20849596
Journal: Radiat Oncol. 2011 Aug 24;6:100.
Title: Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
Author: Gaber, Alexander|Stene, Christina|Hotakainen, Kristina|Nodin, Bjorn|Palmquist, Ingrid|Bjartell, Anders|Stenman, Ulf-Hakan|Jeppsson, Bengt|Johnson, Louis B|Jirstrom, Karin
PMID: 21864386
Journal: Oncology. 2012;82(4):234-41.
Title: Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer.
Author: Koskensalo, Selja|Hagstrom, Jaana|Louhimo, Johanna|Stenman, Ulf-Hakan|Haglund, Caj
PMID: 22508321
Journal: PLoS One. 2013 Oct 25;8(10):e76906.
Title: Concomitant tumor expression of EGFR and TATI/SPINK1 associates with better prognosis in colorectal cancer.
Author: Koskensalo, Selja|Louhimo, Johanna|Hagstrom, Jaana|Lundin, Mikael|Stenman, Ulf-Hakan|Haglund, Caj
PMID: 24204699
Journal: Mol Cancer Res. 2015 Jul;13(7):1130-8.
Title: SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.
Author: Ida, Satoshi|Ozaki, Nobuyuki|Araki, Kimi|Hirashima, Kotaro|Zaitsu, Yoko|Taki, Katsunobu|Sakamoto, Yasuo|Miyamoto, Yuji|Oki, Eiji|Morita, Masaru|Watanabe, Masayuki|Maehara, Yoshihiko|Yamamura, Ken-Ichi|Baba, Hideo|Ohmuraya, Masaki
PMID: 25804623
Journal: Pathol Oncol Res. 2015 Sep;21(4):1201-8.
Title: Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
Author: Chen, Yi-Ting|Tsao, Shu-Chuan|Yuan, Shyng-Shiou F|Tsai, Hung-Pei|Chai, Chee-Yin
PMID: 26037168
Journal: Oncogenesis. 2015 Aug 10;4:e162.
Title: SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression.
Author: Tiwari, R|Pandey, S K|Goel, S|Bhatia, V|Shukla, S|Jing, X|Dhanasekaran, S M|Ateeq, B
PMID: 26258891
Journal: Genet Mol Res. 2015 Dec 22;14(4):17856-63.
Title: A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer.
Author: Proenca, M A|Fernandes, G M M|Russo, A|Lelis, R B|Netinho, J G|Cunrath, G S|Silva, A E|Goloni-Bertollo, E M|Pavarino, E C
PMID: 26782431
Journal: Mol Carcinog. 2016 Dec;55(12):2010-2023.
Title: Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.
Author: Rasanen, Kati|Lehtinen, Elina|Nokelainen, Kristiina|Kuopio, Teijo|Hautala, Laura|Itkonen, Outi|Stenman, Ulf-Hakan|Koistinen, Hannu
PMID: 26663388
Journal: J Clin Pathol. 2016 Apr 22. pii: jclinpath-2016-203638.
Title: Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
Author: Chen, Yi-Ting|Tsao, Shu-Chuan|Tsai, Hung-Pei|Wang, Jaw-Yuan|Chai, Chee-Yin
PMID: 27107100
Journal: Mol Oncol. 2018 Feb;12(2):224-238.
Title: MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.
Author: Rasanen, Kati|Dang, Kien X|Mustonen, Harri|Ho, Tho H|Lintula, Susanna|Koistinen, Hannu|Stenman, Ulf-Hakan|Haglund, Caj|Stenman, Jakob
PMID: 29193645
Journal: Tumour Biol. 2018 Jan;40(1):1010428317752944.
Title: Postoperative CEA is a better prognostic marker than CA19-9, hCGbeta or TATI after resection of colorectal liver metastases.
Author: Peltonen, Reetta|Osterlund, Pia|Lempinen, Marko|Nordin, Arno|Stenman, Ulf-Hakan|Isoniemi, Helena
PMID: 29378497